Publikationen

2013

2520  Albayrak O, Pütter C, Volckmar AL, Cichon S, Hoffmann P, Nöthen MM, Jöckel KH, Schreiber S, Wichmann HE, Faraone SV, Neale BM, Herpertz-Dahlmann B, Lehmkuhl G, Sinzig J, Renner TJ, Romanos M, Warnke A, Lesch KP, Reif A, Schimmelmann BG, Scherag A, Hebebrand J, Hinney A; Psychiatric GWAS Consortium: ADHD Subgroup.  Common obesity risk alleles in childhood attention-deficit/hyperactivity disorder.  Am J Med Genet B Neuropsychiatr Genet. 2013 Mar 26. doi: 10.1002/ajmg.b.32144. [Epub ahead of print] PubMed PMID: 23533005.

2519 Albers C, Leischner H, Verbeek M, Yu C, Illert AL, Peschel C, von Bubnoff N, Duyster J.  The secon dary FLT3-ITD F691L mutation induces resistance to AC220 in FLT3-ITD(+) AML but retains in vitro sensitivity to PKC412 and Sunitinib.  Leukemia. 2013;27(6): 1416-18.

2518 Alexandrov LB, Nik-Zainal S, Wedge DC, Aparicio SA, Behjati S, Biankin AV, Bignell GR, Bolli N, Borg A, Børresen-Dale AL, Boyault S, Burkhardt B, Butler AP, Caldas C, Davies HR, Desmedt C, Eils R, Eyfjörd JE, Foekens JA, Greaves M, Hosoda F, Hutter B, Ilicic T, Imbeaud S, Imielinski M, Jäger N, Jones DT, Jones D, Knappskog S, Kool M, Lakhani SR, López-Otín C, Martin S, Munshi NC, Nakamura H, Northcott PA, Pajic M, Papaemmanuil E, Paradiso A, Pearson JV, Puente XS, Raine K, Ramakrishna M, Richardson AL, Richter J, Rosenstiel P, Schlesner M, Schumacher TN, Span PN, Teague JW, Totoki Y, Tutt AN, Valdés-Mas R, van Buuren MM, van 't Veer L, Vincent-Salomon A, Waddell N, Yates LR; Australian Pancreatic Cancer Genome Initiative; ICGC Breast Cancer Consortium; ICGC MMML-Seq Consortium; ICGC PedBrain, Zucman-Rossi J, Futreal PA, McDermott U, Lichter P, Meyerson M, Grimmond SM, Siebert R, Campo E, Shibata T, Pfister SM, Campbell PJ, Stratton MR. Signatures of mutational processes in human cancer.Nature. 2013 Aug 22;500(7463):415-21. doi: 10.1038/nature12477. Epub 2013 Aug 14.

2517  Alvarez-Baron E, Michel K, Mittelstaedt T, Opitz T, Schmitz F, Beck H, Dietrich D, Becker AJ, Schoch S. RIM3? and RIM4? are key regulators of neuronal arborization. J Neurosci. 2013 Jan 9;33(2):824-39. doi: 10.1523/JNEUROSCI.2229-12.2013.PMID: 23303958.

2516  Anderson-Schmidt H, Adler L, Aly C, Anghelescu IG, Bauer M, Baumgärtner J, Becker J, Bianco R, Becker T, Bitter C, Bönsch D, Buckow K, Budde M, Bührig M, Deckert J, Demiroglu SY, Dietrich D, Dümpelmann M, Engelhardt U, Fallgatter AJ, Feldhaus D, Figge C, Folkerts H, Franz M, Gade K, Gaebel W, Grabe HJ, Gruber O, Gullatz V, Gusky L, Heilbronner U, Helbing K, Hegerl U, Heinz A, Hensch T, Hiemke C, Jäger M, Jahn-Brodmann A, Juckel G, Kandulski F, Kaschka WP, Kircher T, Koller M, Konrad C, Kornhuber J, Krause M, Krug A, Lee M, Leweke M, Lieb K, Mammes M, Meyer-Lindenberg A, Mühlbacher M, Müller MJ, Nieratschker V, Nierste B, Ohle J, Pfennig A, Pieper M, Quade M, Reich-Erkelenz D, Reif A, Reitt M, Reininghaus B, Reininghaus EZ, Riemenschneider M, Rienhoff O, Roser P, Rujescu D, Schennach R, Scherk H, Schmauss M, Schneider F, Schosser A, Schott BH, Schwab SG, Schwanke J, Skrowny D, Spitzer C, Stierl S, Stöckel J, Stübner S, Thiel A, Volz HP, von Hagen M, Walter H, Witt SH, Wobrock T, Zielasek J, Zimmermann J, Zitzelsberger A, Maier W, Falkai PG, Rietschel M, Schulze TG.  The 'DGPPN-Cohort': a national collaboration initiative by the German Association for Psychiatry and Psychotherapy (DGPPN) for establishing a large-scale cohort of psychiatric patients.  Eur Arch Psychiatry Clin Neurosci. 2013 Apr 3. [Epub ahead of print]

2515  Andreassen OA, Djurovic S, Thompson WK, Schork AJ, Kendler KS, O'Donovan MC, Rujescu D, Werge T, van de Bunt M, Morris AP, McCarthy MI; International Consortium for Blood Pressure GWAS; Diabetes Genetics Replication and Meta-analysis Consortium; Psychiatric Genomics Consortium Schizophrenia Working Group, Roddey JC, McEvoy LK, Desikan RS, Dale AM. Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.  Am J Hum Genet. 2013 Feb 7;92(2):197-209. doi: 10.1016/j.ajhg.2013.01.001.

2514  Antonchick A.P, S. López-Tosco, J. Parga, S. Sievers, M. Schürmann, H. Preut, S. Höing, H.R. Schöler, J. Sterneckert, D. Rauh, H. Waldmann.  Highly Enantioselective Catalytic Synthesis of Neurite Growth-Promoting Secoyohimbanes Chemistry & Biology, 2013, 20(4):500-9.

2513  Antony P, Diederich N, Krüger R, Balling R. The hallmarks of Parkinson's disease. FEBS J.2013 May 11. doi: 10.1111/febs.12335. [Epub ahead of print]

2512 Armacki M, Joodi G, Nimmagadda SC, de Kimpe L, PusapatiGV, Vandoninck S,  Van Lint J, Illing A and Seufferlein T.  A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growthby regulating angiogenesis,  Oncogene (2013), 1-14

2511 Aschoff M, Hotz-Wagenblatt A, Glatting KH, Fischer M, Eils R, König R. SplicingCompass: differential splicing detection using RNA-Seq data.  Bioinformatics. 2013 May 1;29(9):1141-8. doi: 10.1093/bioinformatics/btt101. Epub 2013 Feb 28.

2510  Bandapalli OR, Zimmermann M, Kox C, Stanulla M, Schrappe M, Ludwig WD, Koehler R, Muckenthaler MU, Kulozik AE NOTCH1 activation clinically antagonizes the unfavorable effect of PTEN inactivation in BFM-treated children with precursor T-cell acute lymphoblastic leukemia.  Haematologica. 2013 Jun;98(6):928-36. doi: 10.3324/haematol.2012.073585. Epub 2013 Jan 24.

2509 Baraniskin A, Nöpel-Dünnebacke S, Ahrens M, Jensen SG, Zöllner H, Maghnouj A, Wos A, Mayerle J, Munding J, Kost D, Reinacher-Schick A, Liffers S, Schroers R, Chromik AM, Meyer HE, Uhl W, Klein-Scory S, Weiss FU, Stephan C, Schwarte-Waldhoff I, Lerch MM, Tannapfel A, Schmiegel W, Andersen CL, Hahn SA.  Circulating U2 small nuclear RNA fragments as a novel diagnostic biomarker for pancreatic and colorectal adenocarcinoma.  Int J Cancer International Journal of Cancer 2013;132:E48-E57

2508  Bassik MC, Martin Kampmann, Robert Jan Lebbink, Shuyi Wang, Marco Y. Hein, Ina Poser, Jimena Weibezahn, Max A. Horlbeck, Siyuan Chen, Matthias Mann, Anthony A. Hyman, Emily M. LeProust, Michael T. McManus, Jonathan S. Weissman.  A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility.  Cell. 2013;152(4):909-22. doi:10.1016/j.cell.2013.01.030.

2507 Bauer RC, Sanger J, Peschel C, Duyster J, von Bubnoff N.  Sequential inhibitor therapy in CML: In vitro simulation elucidates the pattern of resistance mutations after second and third line treatment.  Clin Cancer Res. 2013;19(11):2962-72.

2506 Becker F, Schubert J, Striano P, Anttonen AK, Liukkonen E, Gaily E, Gerloff C, Müller S, Heußinger N, Kellinghaus C, Robbiano A, Polvi A, Zittel S, von Oertzen TJ, Rostasy K, Schöls L, Warner T, Münchau A, Lehesjoki AE, Zara F, Lerche H, Weber YG.  PRRT2-related disorders: further PKD and ICCA cases and review of the literature.  J Neurol. 2013 Jan 9. [Epub ahead of print] PMID: 23299620.

2505 Becker Kerstin, Claudia Vollbrecht, Ulrike Koitzsch, Katharina Koenig,Jana Fassunke, Sebastian Huss, Peter Nuernberg, Lukas C Heukamp,Reinhard Buettner, Margarete Odenthal, Janine Altmueller, Sabine Merkelbach-Bruse. Deep ion sequencing of amplicon adapter ligated libraries: a novel tool in molecular diagnostics of formalin fixed and paraffin embedded tissues. Journal of Clinical Pathology, jclinpath-2013-201549, in press.

2504 Beetz C, Johnson A, Schuh AL, Thakur S, Varga RE, Fothergill T, Hertel N, Bomba-Warczak E, Thiele H, Nürnberg G, Altmüller J, Saxena R, Chapman ER, Dent EW, Nürnberg P, Audhya A.  Inhibition of TFG function causes hereditary axon degeneration by impairing endoplasmic reticulum structure.  Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5091-6. doi: 10.1073/pnas.1217197110. Epub 2013 Mar 11.

2503  Beier CP, Kumar P, Meyer K, Leukel P, Bruttel V, Aschenbrenner I,Riemenschneider MJ, Fragoulis A, Rümmele P, Lamszus K, Schulz JB, Weis J, Bogdahn U, Wischhusen J, Hau P, Spang R, Beier D.  The cancer stem cell subtype determines immune infiltration of glioblastoma.  Stem Cells Dev. 2012 Oct 10;21(15):2753-61. doi: 10.1089/scd.2011.0660. Epub 2012 Jul 16. PubMed PMID: 22676416; PubMed Central PMCID: PMC3464079.

2502  Berger E, Soldati R, Huebener Nicole, Hohn O, Stermann A, Durmus T, Lobitz S, Zenclussen AC, Christiansen H, Lode HN, Fest S. Salmonella SL7207 application is the most effective DNA vaccine delivery method for successful tumor eradication in a murine model for neuroblastoma.  Cancer Lett. 2013 Jan 18. doi:pii: S0304-3835(13)00032-3. 10.1016/j.canlet.2012.12.026.

2501  Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR, Esko T, Fall T, Ferreira T, Gentilini D, Jackson AU, Luan J, Randall JC, Vedantam S, Willer CJ, Winkler TW, Wood AR, Workalemahu T, Hu YJ, Lee SH, Liang L, Lin DY, Min JL, Neale BM, Thorleifsson G, Yang J, Albrecht E, Amin N, Bragg-Gresham JL, Cadby G, den Heijer M, Eklund N, Fischer K, Goel A, Hottenga JJ, Huffman JE, Jarick I, Johansson A, Johnson T, Kanoni S, Kleber ME, König IR, Kristiansson K, Kutalik Z, Lamina C, Lecoeur C, Li G, Mangino M, McArdle WL, Medina-Gomez C, Müller-Nurasyid M, Ngwa JS, Nolte IM, Paternoster L, Pechlivanis S, Perola M, Peters MJ, Preuss M, Rose LM, Shi J, Shungin D, Smith AV, Strawbridge RJ, Surakka I, Teumer A, Trip MD, Tyrer J, Van Vliet-Ostaptchouk JV, Vandenput L, Waite LL, Zhao JH, Absher D, Asselbergs FW, Atalay M, Attwood AP, Balmforth AJ, Basart H, Beilby J, Bonnycastle LL, Brambilla P, Bruinenberg M, Campbell H, Chasman DI, Chines PS, Collins FS, Connell JM, Cookson WO, de Faire U, de Vegt F, Dei M, Dimitriou M, Edkins S, Estrada K, Evans DM, Farrall M, Ferrario MM, Ferrières J, Franke L, Frau F, Gejman PV, Grallert H, Grönberg H, Gudnason V, Hall AS, Hall P, Hartikainen AL, Hayward C, Heard-Costa NL, Heath AC, Hebebrand J, Homuth G, Hu FB, Hunt SE, Hyppönen E, Iribarren C, Jacobs KB, Jansson JO, Jula A, Kähönen M, Kathiresan S, Kee F, Khaw KT, Kivimäki M, Koenig W, Kraja AT, Kumari M, Kuulasmaa K, Kuusisto J, Laitinen JH, Lakka TA, Langenberg C, Launer LJ, Lind L, Lindström J, Liu J, Liuzzi A, Lokki ML, Lorentzon M, Madden PA, Magnusson PK, Manunta P, Marek D, März W, Mateo Leach I, McKnight B, Medland SE, Mihailov E, Milani L, Montgomery GW, Mooser V, Mühleisen TW, Munroe PB, Musk AW, Narisu N, Navis G, Nicholson G, Nohr EA, Ong KK, Oostra BA, Palmer CN, Palotie A, Peden JF, Pedersen N, Peters A, Polasek O, Pouta A, Pramstaller PP, Prokopenko I, Pütter C, Radhakrishnan A, Raitakari O, Rendon A, Rivadeneira F, Rudan I, Saaristo TE, Sambrook JG, Sanders AR, Sanna S, Saramies J, Schipf S, Schreiber S, Schunkert H, Shin SY, Signorini S, Sinisalo J, Skrobek B, Soranzo N, Stan?áková A, Stark K, Stephens JC, Stirrups K, Stolk RP, Stumvoll M, Swift AJ, Theodoraki EV, Thorand B, Tregouet DA, Tremoli E, Van der Klauw MM, van Meurs JB, Vermeulen SH, Viikari J, Virtamo J, Vitart V, Waeber G, Wang Z, Widén E, Wild SH, Willemsen G, Winkelmann BR, Witteman JC, Wolffenbuttel BH, Wong A, Wright AF, Zillikens MC, Amouyel P, Boehm BO, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Cupples LA, Cusi D, Dedoussis GV, Erdmann J, Eriksson JG, Franks PW, Froguel P, Gieger C, Gyllensten U, Hamsten A, Harris TB, Hengstenberg C, Hicks AA, Hingorani A, Hinney A, Hofman A, Hovingh KG, Hveem K, Illig T, Jarvelin MR, Jöckel KH, Keinanen-Kiukaanniemi SM, Kiemeney LA, Kuh D, Laakso M, Lehtimäki T, Levinson DF, Martin NG, Metspalu A, Morris AD, Nieminen MS, Njølstad I, Ohlsson C, Oldehinkel AJ, Ouwehand WH, Palmer LJ, Penninx B, Power C, Province MA, Psaty BM, Qi L, Rauramaa R, Ridker PM, Ripatti S, Salomaa V, Samani NJ, Snieder H, Sørensen TI, Spector TD, Stefansson K, Tönjes A, Tuomilehto J, Uitterlinden AG, Uusitupa M, van der Harst P, Vollenweider P, Wallaschofski H, Wareham NJ, Watkins H, Wichmann HE, Wilson JF, Abecasis GR, Assimes TL, Barroso I, Boehnke M, Borecki IB, Deloukas P, Fox CS, Frayling T, Groop LC, Haritunian T, Heid IM, Hunter D, Kaplan RC, Karpe F, Moffatt MF, Mohlke KL, O'Connell JR, Pawitan Y, Schadt EE, Schlessinger D, Steinthorsdottir V, Strachan DP, Thorsteinsdottir U, van Duijn CM, Visscher PM, Di Blasio AM, Hirschhorn JN, Lindgren CM, Morris AP, Meyre D, Scherag A, McCarthy MI, Speliotes EK, North KE, Loos RJ, Ingelsson E.   Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet. 2013;45(5):501-12.

2500  Berulava T, Ziehe M, Klein-Hitpass L, Mladenov E, Thomale J, Ruther U, Horsthemke B (2013)  FTO levels affect RNA modifications and the transcriptome.  Eur J Hum Genet 21: 317-323.

2499  Beuschlein F, Boulkroun S, Osswald A, Wieland T, Nielsen HN, Lichtenauer UD, Penton D, Schack VR, Amar L, Fischer E, Walther A, Tauber P, Schwarzmayr T, Diener S, Graf E, Allolio B, Samson-Couterie B, Benecke A, Quinkler M, Fallo F, Plouin PF, Mantero F, Meitinger T, Mulatero P, Jeunemaitre X, Warth R, Vilsen B, Zennaro MC, Strom TM, Reincke M. Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. Nat Genet. 2013 Apr;45(4):440-4

2498 Biancheri R, Cassandrini D, Pinto F, Trovato R, Di Rocco M, Mirabelli-Badenier M, Pedemonte M, Panicucci C, Trucks H, Sander T, Zara F, Rossi A, Striano P, Minetti C, Santorelli FM.  EXOSC3 mutations in isolated cerebellar hypoplasia and spinal anterior horn involvement.  J Neurol. 2013 Apr 7. [Epub ahead of print].

2497  Bigdeli TB, Fanous AH, Riley BP, Reimers M; The Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium (Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L, Visscher PM, Posthuma D, Ruderfer DM, Fanous A, Stefansson H, Steinberg S, Mowry BJ, Golimbet V, De Hert M, Jönsson EG, Bitter I, Pietiläinen OP, Collier DA, Tosato S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bergen SE, Black DW, Børglum AD, Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger CR, Cormican P, Craddock N, Danoy PA, Datta S, de Haan L, Demontis D, Dikeos D, Djurovic S, Donnelly P, Donohoe G, Duong L, Dwyer S, Fink-Jensen A, Freedman R, Freimer NB, Friedl M, Georgieva L, Giegling I, Gill M, Glenthøj B, Godard S, Hamshere M, Hansen M, Hansen T, Hartmann AM, Henskens FA, Hougaard DM, Hultman CM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jürgens G, Kahn RS, Keller MC, Kenis G, Kenny E, Kim Y, Kirov GK, Konnerth H, Konte B, Krabbendam L, Krasucki R, Lasseter VK, Laurent C, Lawrence J, Lencz T, Lerer FB, Liang KY, Lichtenstein P, Lieberman JA, Linszen DH, Lönnqvist J, Loughland CM, Maclean AW, Maher BS, Maier W, Mallet J, Malloy P, Mattheisen M, Mattingsdal M, McGhee KA, McGrath JJ, McIntosh A, McLean DE, McQuillin A, Melle I, Michie PT, Milanova V, Morris DW, Mors O, Mortensen PB, Moskvina V, Muglia P, Myin-Germeys I, Nertney DA, Nestadt G, Nielsen J, Nikolov I, Nordentoft M, Norton N, Nöthen MM, O'Dushlaine CT, Olincy A, Olsen L, O'Neill FA, Orntoft TF, Owen MJ, Pantelis C, Papadimitriou G, Pato MT, Peltonen L, Petursson H, Pickard B, Pimm J, Pulver AE, Puri V, Quested D, Quinn EM, Rasmussen HB, Réthelyi JM, Ribble R, Rietschel M, Riley BP, Ruggeri M, Schall U, Schulze TG, Schwab SG, Scott RJ, Shi J, Sigurdsson E, Silverman JM, Spencer CC, Stefansson K, Strange A, Strengman E, Stroup TS, Suvisaari J, Terenius L, Thirumalai S, Thygesen JH, Timm S, Toncheva D, van den Oord E, van Os J, van Winkel R, Veldink J, Walsh D, Wang AG, Wiersma D, Wildenauer DB, Williams HJ, Williams NM, Wormley B, Zammit S, Sullivan PF, O'Donovan MC, Daly MJ, Gejman PV), Chen X, Kendler KS, Bacanu SA.  On schizophrenia as a 'disease of humanity'.  Schizophr Res. 2013 Jan;143(1):223-4. doi: 10.1016/j.schres.2012.10.036.

2496 Binia A, Van Stiphout N, Liang L, Michel S, Bhavsar PK, Fan Chung K,Brightling CE, Barnes PJ, Kabesch M, Bush A, Cookson WO, Moffatt MF.  A Polymorphism Affecting MYB Binding within the Promoter of the PDCD4 Gene isAssociated with Severe Asthma in Children.  Hum Mutat. 2013 Apr 18. PMID: 23606399.

2495 Blanc, M., Hsieh, W.Y., Robertson, K.A., Kropp K.A., Forster, T., Shui, G., Lacaze, P., Watterson, S., Griffiths, S.J., Spann, N.J., Meljon, A., Talbot, S., Krishnan, K., Douglas F Covey, D.F., Wenk, M.R., Craigon, M., Ruzsics, Z., Haas, J., Angulo, A., Griffiths, W.J., Glass, C.K., Wang, Y., Ghazal, P.  The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response. Immunity. 2013 Jan 24;38(1):106-18. doi: 10.1016/j.immuni.2012.11.004. Epub 2012 Dec 27.

2494  Børglum AD, Demontis D, Grove J, Pallesen J, Hollegaard MV, Pedersen CB, Hedemand A,Mattheisen M; GROUP investigators, Uitterlinden A, Nyegaard M, Orntoft T, Wiuf C, Didriksen M, Nordentoft M, Nöthen MM, Rietschel M, Ophoff RA, Cichon S, Yolken RH, Hougaard DM, Mortensen PB, Mors O.  Genome-wide study of association and interaction with maternal cytomegalovirus infection suggests new schizophrenia loci.  Mol Psychiatry. 2013 Jan 29. doi: 10.1038/mp.2013.2.

2493 Bos M, Gardizi M, Schildhaus HU, Heukamp LC, Geist T, Kaminsky B, Zander T, Nogova L, Scheffler M, Dietlein M, Kobe C, Holstein A, Maintz D, Büttner R, Wolf J. Complete metabolic response in a patient with repeatedly relapsed non-small cell lung cancer harboring ros1 gene rearrangement after treatment with crizotinib. Lung Cancer 2013.

2492 Brand I., S. Fliegel, R. Spanagel, H.R. Noori.  Global Ethanol-Induced Enhancements of the Monoaminergic Neurotransmission: A Meta-Analysis, 2013.  Alcohol Clin Exp Res. 2013 Jun 28. doi: 10.1111/acer.12207. [Epub ahead of print]

2491 Brockmann M, Poon E, Berry T, Carstensen A, Deubzer HE, Rycak L, Jamin Y, Thway K, Robinson SP, Roels F, Witt O, Fischer M, Chesler L, Eilers M. Small molecule inhibitors of Aurora-A induce proteasomal degradation of N-Myc in childhood neuroblastoma.  Cancer Cell. 2013 Jun 19. pii: S1535-6108(13)00232-8. doi: 10.1016/j.ccr.2013.05.005. [Epub ahead of print].

2490 Brueckner LM, Hess EM, Schwab M, Savelyeva L. Instability at the FRA8I common fragile site disrupts the genomic integrity of the KIAA0146, CEBPD and PRKDC genes in colorectal cancer.  Cancer Lett. 2013 Apr 16. doi:pii: S0304-3835(13)00327-3. 10.1016/j.canlet.2013.04.007. PMID:23603433.

2489 Buske-Kirschbaum A, Schmitt J, Plessow F, Romanos M, Weidinger S, Roessner V.  Psychoendocrine and psychoneuroimmunological mechanisms in the comorbidity of atopic eczema and attention deficit/hyperactivity disorder.  Psychoneuroendocrinology 2013; 38:12-23.

2488 Büttner R, Wolf J, Thomas RK. Lessons learned from lung cancer genomics: The emerging concept of individualized diagnostics and treatment. J Clin Oncol 2013.

2487 Cacciaglia R, Nees F, Pohlack ST, Ruttorf M, Winkelmann T, Witt SH, Nieratschker V, Rietschel M, Flor H.  A risk variant for alcoholism in the NMDA receptor affects amygdala activity during fear conditioning in humans.  Biol Psychol. 2013 May 18. doi:pii: S0301-0511(13)00124-5. 10.1016/j.biopsycho.2013.05.006. [Epub ahead of print]

2486 Caldelari I, Chao Y, Romby P, Vogel J. Caldelari I, Chao Y, Romby P, Vogel J.  RNA-mediated regulation in pathogenic bacteria Bacterial Pathogens and Pathogenesis (eds. Cossart P, Maloy S), CSH Press, in press

2485 Caldwell JH, Klevanski M, Saar M, Müller UC.  Roles of the amyloid precursor protein family in the peripheral nervous system.  Mech Dev. 2012 Nov 29. pii: S0925-4773(12)00112-8. doi: 10.1016/j.mod.2012.11.001. [Epub ahead of print]

2484 Campa, D., Rizzato, C., Bauer, A.S., Werner, J., Capurso, G., Costello, E., Talar-Wojnarowska, R., Jamroziak, K., Pezzilli, R., Gazouli, M., Khaw, K.-T., Key, T.J., Bambi, F., Heller, A., Landi, L., Vodickova, L., Theodoropoulos, G., Bugert, P., Vodicka, P., Hoheisel, J.D., Neoptolemos, J.P., Soucek, P., Büchler, M.W., Giese, N. & Canzian, F.  Lack of replication of seven pancreatic cancer susceptibility loci identified in two Asian populations. Cancer Epidemiol. Biomarkers Prev., in press

2483 CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA, Stirrups K, König IR, Cazier JB, Johansson A, Hall AS, Lee JY, Willer CJ, Chambers JC, Esko T, Folkersen L, Goel A, Grundberg E, Havulinna AS, Ho WK, Hopewell JC, Eriksson N, Kleber ME, Kristiansson K, Lundmark P, Lyytikäinen LP, Rafelt S, Shungin D, Strawbridge RJ, Thorleifsson G, Tikkanen E, Van Zuydam N, Voight BF, Waite LL, Zhang W, Ziegler A, Absher D, Altshuler D, Balmforth AJ, Barroso I, Braund PS, Burgdorf C, Claudi-Boehm S, Cox D, Dimitriou M, Do R; DIAGRAM Consortium; CARDIOGENICS Consortium, Doney AS, El Mokhtari N, Eriksson P, Fischer K, Fontanillas P, Franco-Cereceda A, Gigante B, Groop L, Gustafsson S, Hager J, Hallmans G, Han BG, Hunt SE, Kang HM, Illig T, Kessler T, Knowles JW, Kolovou G, Kuusisto J, Langenberg C, Langford C, Leander K, Lokki ML, Lundmark A, McCarthy MI, Meisinger C, Melander O, Mihailov E, Maouche S, Morris AD, Müller-Nurasyid M; MuTHER Consortium, Nikus K, Peden JF, Rayner NW, Rasheed A, Rosinger S, Rubin D, Rumpf MP, Schäfer A, Sivananthan M, Song C, Stewart AF, Tan ST, Thorgeirsson G, van der Schoot CE, Wagner PJ; Wellcome Trust Case Control Consortium, Wells GA, Wild PS, Yang TP, Amouyel P, Arveiler D, Basart H, Boehnke M, Boerwinkle E, Brambilla P, Cambien F, Cupples AL, de Faire U, Dehghan A, Diemert P, Epstein SE, Evans A, Ferrario MM, Ferrières J, Gauguier D, Go AS, Goodall AH, Gudnason V, Hazen SL, Holm H, Iribarren C, Jang Y, Kähönen M, Kee F, Kim HS, Klopp N, Koenig W, Kratzer W, Kuulasmaa K, Laakso M, Laaksonen R, Lee JY, Lind L, Ouwehand WH, Parish S, Park JE, Pedersen NL, Peters A, Quertermous T, Rader DJ, Salomaa V, Schadt E, Shah SH, Sinisalo J, Stark K, Stefansson K, Trégouët DA, Virtamo J, Wallentin L, Wareham N, Zimmermann ME, Nieminen MS, Hengstenberg C, Sandhu MS, Pastinen T, Syvänen AC, Hovingh GK, Dedoussis G, Franks PW, Lehtimäki T, Metspalu A, Zalloua PA, Siegbahn A, Schreiber S, Ripatti S, Blankenberg S, Perola M, Clarke R, Boehm BO, O'Donnell C, Reilly MP, März W, Collins R, Kathiresan S, Hamsten A, Kooner JS, Thorsteinsdottir U, Danesh J, Palmer CN, Roberts R, Watkins H, Schunkert H, Samani NJ.  Large-scale association analysis identifies new risk loci for coronary artery disease.  Nat Genet. 2013 Jan; 45(1):25-33. doi: 10.1038/ng.2480. Epub 2012 Dec 2. PubMed PMID: 23202125.

2482 Carotenuto M, Pedone E, Diana D, de Antonellis P, D?eroski S, Marino N, Navas L, Di Dato V, Scoppettuolo MN, Cimmino F, Correale S, Pirone L, Monti SM, Bruder E, Zenko B, Slavkov I, Pastorino F, Ponzoni M, Schulte JH, Schramm A, Eggert A, Westermann F, Arrigoni G, Accordi B, Basso G, Saviano M, Fattorusso R, Zollo M.  Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction.  Sci Rep. 2013;3:1351. doi: 10.1038/srep01351. PubMed PMID: 23448979;PubMed Central PMCID: PMC3584926.

2481 Charlet K, Schlagenhauf F, Richter A, Naundorf K, Dornhof L, Weinfurtner C, König F, Walaszek B, Schubert F, Müller CA, Gutwinski S, Seissinger A, Schmitz L, Walter H, Beck A, Gallinat J, Kiefer F, Heinz A.  Neural activation during processing of aversive faces predicts treatment outcome in alcoholism.  Addict Biol. 2013 Mar 7. doi: 10.1111/adb.12045. [Epub ahead of print]

2480 Chatterjee S, Heukamp LC, Siobal M, Schöttle J, Wieczorek C, Peifer M, Frasca D, Koker M, König K, Meder L, Rauh D, Buettner R, Wolf J, Brekken RA, Neumaier B, Christofori G, Thomas RK, Ullrich RT.  Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer. J Clin Invest. 2013 Apr 1;123(4):1732-40.

2479 Che, X., Oliver, S.L., Reichelt, M., Sommer, M.H., Haas, J., Rovi? , T.L., Arvin A.M.  ORF11 Protein Interacts with the ORF9 Essential Tegument Protein in Varicella-Zoster Virus Infection.  J Virol. 2013 May;87(9):5106-17. doi: 10.1128/JVI.00102-13. Epub 2013 Feb 20.

2478 Chen, D. T., Jiang, X., Akula, N., Shugart, Y. Y., Wendland, J. R., Steele, C. J. M., Kassem, L., et al.  Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder.  Molecular psychiatry, 18(2), 195?205. doi:10.1038/mp.2011.157.

2477 Cheret C, Willem M, Fricker FR, Wende H, Wulf-Goldenberg A, Tahirovic S, Nave KA, Saftig P, Haass C, Garratt AN, Bennett DL, Birchmeier C. Bace1 and Neuregulin-1 (Nrg1) cooperate to control formation and maintenance of muscle spindles.  EMBO J. 2013 (in press) (Förderung durch BMBF/NGFN-Plus erwähnt).

2476 Chirasani SR, Leukel P, Gottfried E, Hochrein J, Stadler K, Neumann B, Oefner PJ, Gronwald W, Bogdahn U, Hau P, Kreutz M, Grauer OM.  Diclofenac inhibitslactate formation and efficiently counteracts local immune suppression in amurine glioma model.  Int J Cancer. 2013 Feb 15;132(4):843-53. doi: 10.1002/ijc.27712. Epub 2012 Jul 21. PubMed PMID: 22752934.

2475 Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL, Hottenga JJ, Fischer K, Esko T, Surakka I, Broer L, Nyholt DR, Mateo Leach I, Salo P, Hägg S, Matthews MK, Palmen J, Norata GD, O'Reilly PF, Saleheen D, Amin N, Balmforth AJ, Beekman M, de Boer RA, Böhringer S, Braund PS, Burton PR, Craen AJ, Denniff M, Dong Y, Douroudis K, Dubinina E, Eriksson JG, Garlaschelli K, Guo D, Hartikainen AL, Henders AK, Houwing-Duistermaat JJ, Kananen L, Karssen LC, Kettunen J, Klopp N, Lagou V, van Leeuwen EM, Madden PA, Mägi R, Magnusson PK, Männistö S, McCarthy MI, Medland SE, Mihailov E, Montgomery GW, Oostra BA, Palotie A, Peters A, Pollard H, Pouta A, Prokopenko I, Ripatti S, Salomaa V, Suchiman HE, Valdes AM, Verweij N, Viñuela A, Wang X, Wichmann HE, Widen E, Willemsen G, Wright MJ, Xia K, Xiao X, van Veldhuisen DJ, Catapano AL, Tobin MD, Hall AS, Blakemore AI, van Gilst WH, Zhu H, Consortium C, Erdmann J, Reilly MP, Kathiresan S, Schunkert H, Talmud PJ, Pedersen NL, Perola M, Ouwehand W, Kaprio J, Martin NG, van Duijn CM, Hovatta I, Gieger C, Metspalu A, Boomsma DI, Jarvelin MR, Slagboom PE, Thompson JR, Spector TD, van der Harst P, Samani NJ.  Identification of seven loci affecting mean telomere length and their association with disease.  Nat Genet. 2013 Apr;45(4):422-7. doi: 10.1038/ng.2528. PubMed PMID: 23535734.

2474 Conrad KD, Giering F, Erfurth C, Neumann A, Fehr C, Meister G, Niepmann M. MicroRNA-122 dependent binding of Ago2 protein to hepatitis C virus RNA is associated with enhanced RNA stability and translation stimulation.  PLOS One, 8(2):e56272.

2473  Couturier-Maillard A, Secher T, Rehman A, Normand S, De Arcangelis A, Haesler R, Huot L, Grandjean T, Bressenot A, Delanoye-Crespin A, Gaillot O, Schreiber S, Lemoine Y, Ryffel B, Hot D, Nùñez G, Chen G, Rosenstiel P*, Chamaillard M. NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.  J Clin Invest. 2013 Jan 2. doi:pii: 62236. 10.1172/JCI62236. [Epub ahead of print] PubMed PMID: 23281400; PubMed Central PMCID: PMC3561825 * denotes shared senior authorship.

2472  Cross-Disorder Group of the Psychiatric Genomics Consortium, Smoller JW, Craddock N, Kendler K, Lee PH, Neale BM, Nurnberger JI, Ripke S, Santangelo S, Sullivan PF.
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.  Lancet. 2013 Apr 20;381(9875):1371-9.

2471  Crotti L, Johnson CN, Graf E, De Ferrari GM, Cuneo BF, Ovadia M, Papagiannis J, Feldkamp MD, Rathi SG, Kunic JD, Pedrazzini M, Wieland T, Lichtner P, Beckmann BM, Clark T, Shaffer C, Benson DW, Kääb S, Meitinger T, Strom TM, Chazin WJ, Schwartz PJ, George AL Jr. Calmodulin mutations associated with recurrent cardiac arrest in infants. Circulation. 2013 Mar 5;127(9):1009-17.

2470 Daschkey S., Röttger S., Giri A., Bradtke J., Teigler-Sclegel A., Meister G., Borkhatdt A., Landgraf P.  MicroRNAs distinguish cytogenetic subgroups in pediatric AML and contribute to complex regulatory networks in AML-relevant pathways.  PLOS One, 8(2):e56334.

2469 de Groot JC, Weidner C, Krausze J, Kawamoto K, Schroeder FC, Sauer S, Büssow K.  Structural Characterization of Amorfrutins Bound to the Peroxisome Proliferator-Activated Receptor ?.  Journal of Medicinal Chemistry. 2013; 56(4):1535-1543

2468 Degenhardt F, Priebe L, Strohmaier J, Herms S, Hoffmann P, Mattheisen M,Mössner R, Nenadic I, Sauer H, Rujescu D, Maier W, Schulze TG, Rietschel M,Nöthen MM, Cichon S.  No evidence for an involvement of copy number variation in ABCA13 in schizophrenia, bipolar disorder, or major depressive disorder.  Psychiatr Genet. 2013 Feb;23(1):45-6.

2467 Deo M, Huang JL, Fuchs H, Hrabé de Angelis M, Van Raamsdonk CD.  Differential effects of neurofibromin gene dosage on melanocyte development.  J Invest Dermatol. 2013 Jan;133(1):49-58. doi: 10.1038/jid.2012.240.

2466 DEUBZER HE, Schier MC, Oehme I, Lodrini M, Haendler B, Sommer A, WITT O. HDAC11 is a novel drug target in carcinomas.  Int J Cancer. 2013 May 1;132(9):2200-8. doi: 10.1002/ijc.27876. Epub 2012 Oct 25.

2465 Diffner E, Beck D, Gudgin E, Thoms JA, Knezevic K, Pridans C, Foster S, Goode D, Lim WK, Boelen L, Metzeler KH, Micklem G, Bohlander SK, Buske C, Burnett A, Ottersbach K, Vassiliou GS, Olivier J, Wong JW, Göttgens B, Huntly BJ, Pimanda JE.  Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.  Blood. 2013;121:2289-2300.

2464 Dörge, P., Meissner, B., Zimmermann, M., Möricke, A., Schrauder, A., Bouquin, J.P., Schewe, J.P., Harbott,J., Teigler-Schlegel, A., Ratei, R., Ludwig, W.D., Koehler, R., Bartram, C.R., Schrappe, M, Stanulla, M., Cario, G.  IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.  Haematologica. 2013, 98:428-32.

2463 Dreidax D, Gogolin S, Schroeder C, Muth D, Brueckner LM, Hess EM, Zapatka M, Theißen J, Fischer M, Ehemann V, Schwab M, Savelyeva L, Westermann F. Low p14ARF expression in neuroblastoma cells is associated with repressed histone mark status, and enforced expression induces growth arrest and apoptosis.  Hum Mol Genet, 2013, 22(9): 1735-1745.

2462 Dudek J, Cheng I-F, Balleininger M, Vaz FM, Streckfuss-Bömeke K, Hübscher D, Vukotic M, Wanders RJA, Rehling P, Guan K.  Cardolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome.  Stem Cell Res. 2013; doi.10.1016/j.scr.2013.05.005.

2461 Eberl HC, Cornelia G. Spruijt, Christian D. Kelstrup, Michiel Vermeulen and Matthias Mann.  A map of general and specialized chromatin readers in mouse tissues generated by highly sensitive, label-free interaction proteomics.  Mol Cell. 2013; 49(2):368-78. doi:10.1016/j.molcel.2012.10.026.

2460 Ellinghaus D, Baurecht H, Esparza-Gordillo J, Rodríguez E, Matanovic A, Marenholz I, Hübner N, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, Heim K, Herder C, Hirota T, Tamari M, Kubo M, Takahashi A, Nakamura Y, Tsoi LC, Stuart P, Elder JT, Sun L, Zuo X, Yang S, Zhang X, Hoffmann P, Nöthen MM, Fölster-Holst R, Winkelmann J, Illig T, Boehm BO, Duerr RH, Büning C, Brand S, Glas J, McAleer MA, Fahy CM, Kabesch M, Brown S, McLean WH, Irvine AD, Schreiber S, Lee YA, Franke A, Weidinger S.  High-density genotyping study identifies four new susceptibility loci for atopic dermatitis.  Nat Genet. 2013 Jun 2. doi: 10.1038/ng.2642.

2459 Ellinghaus D, Zhang H, Zeissig S, Lipinski S, Till A, Jiang T, Stade B, Bromberg Y, Ellinghaus E, Keller A, Rivas MA, Skieceviciene J, Doncheva NT, Liu X, Liu Q, Jiang F, Forster M, Mayr G, Albrecht M, Hasler R, Boehm BO, Goodall J, Berzuini CR, Lee J, Andersen V, Vogel U, Kupcinskas L, Kayser M, Krawczak M, Nikolaus S, Weersma RK, Ponsioen CY, Sans M, Wijmenga C, Strachan DP, McArdle WL, Vermeire S, Rutgeerts P, Sanderson JD, Mathew CG, Vatn MH, Wang J, Nothen MM, Duerr RH, Buning C, Brand S, Glas J, Winkelmann J, Illig T, Latiano A, Annese V, Halfvarson J, Damato M, Daly MJ, Nothnagel M, Karlsen TH, Subramani S, Rosenstiel P, Schreiber S, Parkes M, Franke A (2013).  Association Between Variants of PRDM1 and NDP52 and Crohns Disease, Based on Exome Sequencing and Functional Studies.  Gastroenterology, Epub ahead of print.

2458 Enciso-Mora V et al.  Deciphering the 8q24.21 association for glioma.  Hum Mol Genet. Epub 2013 Feb 20.

2457 Esparza-Gordillo J, Schaarschmidt H, Liang L, Cookson WO, Bauerfeind A, Lee-Kirsch MA, Nemat K, Henderson J, Paternoster L, Harper JL, Mangold E, Nothen MM, Ruschendorf F, Kerscher T, Marenholz I, Matanovic A, Lau S, Keil T, Bauer CP, Kurek M, Ciechanowicz A, Macek M, Franke A, Kabesch M, Hubner N, Abecasis GR, Weidinger S, Moffatt MF, Lee YA.   A functional IL6R variant is a risk factor for persistent eczema. J Allergy Clin Immunol. 2013 Apr 9. doi:pii: S0091-6749(13)00322-9. 10.1016/j.jaci.2013.01.057.

2456 Fang Z., C. Grütter, D. Rauh. Strategies for the Selective Regulation of Kinases with Allosteric Modulators - Exploiting Exclusive Structural Features. ACS Chem Biol, 2013, 8(1):58-70.

2455 Fehr C, Sommerlad D, Sander T, Anghelescu I, Dahmen N, Szegedi A, Mueller C, Zill P, Soyka M, Preuss UW.  Association of VMAT2 gene polymorphisms with alcohol dependence.  J Neural Transm. 2013 Mar 17. [Epub ahead of print].

2454 Feldmann R, Fischer C, Kodelja V, Behrens S, Haas S, Vingron M, Timmermann B, Geikowski A, Sauer S.  Genome-wide analysis of LXR? activation reveals new transcriptional networks in human atherosclerotic foam cells.  Nucleic Acids Res. 2013 Apr 1;41(6):3518-31.

2453 Feldmann R, Geikowski A, Weidner C, Witzke A, Kodelja V, Schwarz T, Gabriel M, Erker T, Sauer S. Foam cell specific LXR? ligand.  PLoS One. 2013;8(2):e57311.

2452 Fernández-Rhodes L, Demerath EW, Cousminer DL, Tao R, Dreyfus JG, Esko T, Smith AV, Gudnason V, Harris TB, Launer L, McArdle PF, Yerges-Armstrong LM, Elks CE, Strachan DP, Kutalik Z, Vollenweider P, Feenstra B, Boyd HA, Metspalu A, Mihailov E, Broer L, Zillikens MC, Oostra B, van Duijn CM, Lunetta KL, Perry JR, Murray A, Koller DL, Lai D, Corre T, Toniolo D, Albrecht E, Stöckl D, Grallert H, Gieger C, Hayward C, Polasek O, Rudan I, Wilson JF, He C, Kraft P, Hu FB, Hunter DJ, Hottenga JJ, Willemsen G, Boomsma DI, Byrne EM, Martin NG, Montgomery GW, Warrington NM, Pennell CE, Stolk L, Visser JA, Hofman A, Uitterlinden AG, Rivadeneira F, Lin P, Fisher SL, Bierut LJ, Crisponi L, Porcu E, Mangino M, Zhai G, Spector TD, Buring JE, Rose LM, Ridker PM, Poole C, Hirschhorn JN, Murabito JM, Chasman DI, Widen E, North KE, Ong KK, Franceschini N.  Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent.  Am J Epidemiol. 2013 Apr 4. [Epub ahead of print].

2451  Filatova A, Acker T, Garvalov BK.  The cancer stem cell niche(s): the crosstalk between glioma stem cells and their microenvironment. Biochim Biophys Acta. 2013:1830(2):2496-508.

2450 Fleck D, van Bebber F, Colombo A, Galante C, Schwenk BM, Rabe L, Hampel H, Novak B, Kremmer E, Tahirovic S, Edbauer D, Lichtenthaler SF, Schmid B, Willem M, Haass C. Dual cleavage of Neuregulin 1 type III by BACE1 or ADAM17 liberates its EGF-like domain and allows paracrine signaling.  J Neurosci. 2013 May 1;33(18):7856-69. doi: 10.1523/JNEUROSCI.3372-12.2013.

2449 Fliegel S., I. Brand, R. Spanagel, H.R. Noori. Ethanol-Induced Alterations of the Extracellular Amino Acid Concentrations: A Meta-Analysis, 2013 Alcohol Clin Exp Res [in press]

2448 Forster M, Forster P, Elsharawy A, Hemmrich G, Kreck B, Wittig M, Thomsen I, Stade B, Barann M, Ellinghaus D, Petersen BS, May S, Melum E, Schilhabel MB, Keller A, Schreiber S, Rosenstiel P, Franke A.  From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software.  Nucleic Acids Res. 41(1): e16. Jan 2013.

2447 Fredebohm, J., Wolf, J., Hoheisel, J.D. & Böttcher, M. Depletion of RAD17 sensitizes pancreatic cancer cells to gemcitabine.  J Cell Sci., in press.

2446 Freunscht I, Popp B, Blank R, Endele S, Moog U, Petri H, Prott EC, Reis A, Rübo J, ZAbel B, Zenker M, Hebebrand J, Wieczorek D.  Behavioral phenotype in five individuals with de novo mutations within the GRIN2B gene.  Behav Brain Funct 2013, 29: 20.

2445 Ganesh SK, Tragante V, Guo W, Guo Y, Lanktree MB, Smith EN, Johnson T, Castillo BA, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Franceschini N, Gaunt TR, Gho JM, Gieger C, Gong Y, Isaacs A, Kleber ME, Leach IM, McDonough CW, Meijs MF, Mellander O, Molony CM, Nolte IM, Padmanabhan S, Price TS, Rajagopalan R, Shaffer J, Shah S, Shen H, Soranzo N, van der Most PJ, Van Iperen EP, Van Setten JA, Vonk JM, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Boer JM, Boerwinkle E, Burkley B, Burt A, Chakravarti A, Chen W, Cooper-Dehoff RM, Curtis SP, Dreisbach A, Duggan D, Ehret GB, Fabsitz RR, Fornage M, Fox E, Furlong CE, Gansevoort RT, Hofker MH, Hovingh GK, Kirkland SA, Kottke-Marchant K, Kutlar A, Lacroix AZ, Langaee TY, Li YR, Lin H, Liu K, Maiwald S, Malik R; CARDIOGRAM, METASTROKE, Murugesan G, Newton-Cheh C, O'Connell JR, Onland-Moret NC, Ouwehand WH, Palmas W, Penninx BW, Pepine CJ, Pettinger M, Polak JF, Ramachandran VS, Ranchalis J, Redline S, Ridker PM, Rose LM, Scharnag H, Schork NJ, Shimbo D, Shuldiner AR, Srinivasan SR, Stolk RP, Taylor HA, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Winkelmann BR, Wyatt S, Young JH, Boehm BO, Caulfield MJ, Chasman DI, Davidson KW, Doevendans PA, Fitzgerald GA, Gums JG, Hakonarson H, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W; LifeLines Cohort Study, März W, Mitchell BD, Murray SS, Oldehinkel AJ, Rader DJ, Reilly MP, Reiner AP, Schadt EE, Silverstein RL, Snieder H, Stanton AV, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Johnson AD, Munroe PB, de Bakker PI, Zhu X, Levy D, Keating BJ, Asselbergs FW. Loci influencing blood pressure identified using a cardiovascular gene-centric array. Hum Mol Genet. 2013 Feb 7. [Epub ahead of print]

2444 Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Zucknick M, Oakes C, Fleig V, Allegra D, Caudron-Herger M et al:  Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia correlates with downregulation in cis of a gene cluster regulating NF-kB.  PLoS Genet. 2013 Apr;9(4):e1003373. doi: 10.1371/journal.pgen.1003373. Epub 2013 Apr 4.

2443 Garnier S, Truong V, Brocheton J, Zeller T, Rovital M, Wild PS, Ziegler A; Cardiogenics Consortium, Munzel T, Tiret L, Blankenberg S, Deloukas P, Erdmann J, Hengstenberg C, Samani NJ, Schunkert H, Ouwehand WH, Goodall AH, Cambien F, Trégouët DA.  Genome-wide haplotype analysis of cis expression quantitative trait Loci in monocytes. PLoS Genet. 2013 Jan;9(1):e1003240.

2442 GENDEP Investigators; MARS Investigators; STAR*D Investigators; Collaborators: Uher R, Tansey KE, Rietschel M, Henigsberg N, Maier W, Mors O, Hauser J, Placentino A, Souery D, Farmer A, Aitchison KJ, Craig I, McGuffin P, Lewis CM, Ising M, Lucae S, Binder EB, Kloiber S, Holsboer F, Müller-Myhsok B, Ripke S, Hamilton SP, Soundy J, Laje G, McMahon FJ, Fava M, Rush A, Perlis RH.  Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.  Am J Psychiatry. 2013 Feb 1;170(2):207-17.

2441 Giatrakos S, Huse K, Kanni T, Tzanetakou V, Kramer M, Grech I, Papadavid E, Katoulis A, Stavrianeas N, Nothnagel M, Platzer M, Bauer M, Giamarellos-Bourboulis EJ (2013).  Haplotypes of IL-12R?1 impact on the clinical phenotype of hidradenitis suppurativa.  Cytokine 62(2):297-301.

2440 Giesert F, Hofmann A, Bürger A, Zerle J, Kloos K, Hafen U, Ernst L, Zhang J, Vogt-Weisenhorn DM, Wurst W. Expression analysis of lrrk1, lrrk2 and lrrk2 splice variants in mice.  PLoS One. 2013 May 10;8(5):e63778. doi: 10.1371/journal.pone.0063778. Print 2013.

2439 Gillardon F, Kremmer E, Froehlich T, Ueffing M, Hengerer B, Gloeckner CJ.  ATP-competitive LRRK2 inhibitors interfere with monoclonal antibody binding to the kinase domain of LRRK2 under native conditions.  J Neurosci Methods. 2013 Mar 30;214(1):62-8. doi: 10.1016/j.jneumeth.2012.12.015.

2438 Gogolin S, Ehemann V, Becker G, Brueckner LM, Dreidax D, Bannert S, Nolte I, Savelyeva L, Bell E, Westermann F.  CDK4 inhibition restores G?-S arrest inMYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage.  Cell Cycle. 2013 Apr 1;12(7):1091-104. doi: 10.4161/cc.24091. Epub 2013 Mar 5. PubMed PMID: 23462184.

2437 Gogolin, S., Batra, R., Harder, N., Ehemann, V., Pa hausen, T., Diessl, N.,Gade ,S., Nolte, I., Rohr, K., König, R., Westermann, F. MYCN-mediatedoverexpression of mitotic spindle regulatory genes and loss of p53-p21 functionjointly support the survival of tetraploid neuroblastoma cells.  CancerLetters, 331(1):35-45.

2436 Goubau C, Devriendt K, van der AA N, Crepel A, Wieczorek D, Kleefstra T, Willemsen MH, Rauch A, Tzschach A, de Ravel T, Leemans P, van Geet C, Buyse G, Freson K.  Platelet defecs in congenital variant of Rett syndrome patients with FOXG1 mutations or reduced expression due to a position effect at 14q12.  Eur J Hum Genet 2013, doi: 10.1038/ejhg.2013.86.

2435 Grathwohl SA, Jucker M.  Replacement of osmotic minipumps to extend the intracerebral infusion time of compounds into the mouse brain. Biotechniques Bio Techniques, accepted with minor revision.

2434 Gregor A, Oti M, Kouwenhoven EN, Hoyer J, Sticht H, Ekici AB, Kjaergaard S, Rauch A, Stunnenberg HG, Uebe S, Vasileiou G, Reis A, Zhou H, Zweier C. De Novo Mutations in the Genome Organizer CTCF Cause Intellectual Disability. Am J Hum Genet. 2013, 93(1):124-31.

2433  Gries J.,  D. Schumacher, J. Arand, P. Lutsik, M. Rivera-Markelova, I. Fichtner, J. Walter, C. Sers and S. Tierling. Bi-PROF: Bisulfite profiling of target regions using 454 GS FLX Titanium technology. Epigenetics. 2013 Jun 10;8(7). [Epub ahead of print]

2432  Grimm C., L. Chavez, M. Vilardell, A.L. Farrall, S. Tierling, J.W. Boehm, P. Grote, M. Lienhard, J. Dietrich, B. Timmermann, J. Walter, M.R. Schweiger, H. Lehrach, R. Herwig, B.G. Herrmann and M. Morkel. DNA-Methylome Analysis of Mouse Intestinal Adenoma Identifies a Tumour-Specific Signature That Is Partly Conserved in Human Colon Cancer. PLoS Genet. 2013 9(2):e1003250. doi:10.1371/journal.pgen.1003250.

2431  Grimm MO, Haupenthal VJ, Rothhaar TL, Zimmer VC, Grösgen S, Hundsdörfer B, Lehmann J, Grimm HS, Hartmann T Effect of Different Phospholipids on ?-Secretase Activity in the Non-Amyloidogenic Pathway of Alzheimer's Disease. Int J Mol Sci. 2013 Mar 13;14(3):5879-98.

2430 Guha S, Rees E, Darvasi A, Ivanov D, Ikeda M, Bergen SE, Magnusson PK,Cormican P, Morris D, Gill M, Cichon S, Rosenfeld JA, Lee A, Gregersen PK, Kane JM, Malhotra AK, Rietschel M, Nöthen MM, Degenhardt F, Priebe L, Breuer R, Strohmaier J, Ruderfer DM, Moran JL, Chambert KD, Sanders AR, Shi J, Kendler K, Riley B, O'Neill T, Walsh D, Malhotra D, Corvin A, Purcell S, Sklar P, Iwata N, Hultman CM, Sullivan PF, Sebat J, McCarthy S, Gejman PV, Levinson DF, Owen MJ, O'Donovan MC, Lencz T, Kirov G; Molecular Genetics of Schizophrenia Consortium; Wellcome Trust Case Control Consortium 2.  Implication of a rare deletion at distal 16p11.2 in schizophrenia. JAMA Psychiatry. 2013 Mar;70(3):253-60. doi: 10.1001/2013.jamapsychiatry.71.

2429 Guo Y, Lanktree MB, Taylor KC, Hakonarson H, Lange LA, Keating BJ; IBC 50K SNP array BMI Consortium. Gene-centric meta-analyses of 108 912 individuals confirm known body mass index loci and reveal three novel signals. Hum Mol Genet 2013;22:184-201.

2428 Haedel S, Wirth C, Rapp M, Gallinat J, Schubert F.  Effects of Age and Sex on the Concentrations of Glutamate and Glutamine in the Human Brain.  J Magn Reson Imaging. 2013 Apr 5. doi: 10.1002/jmri.24123. [Epub ahead of print]

2427 Haenisch B, Herms S, Mattheisen M, Steffens M, Breuer R, Strohmaier J, Degenhardt F, Schmäl C, Lucae S, Maier W, Rietschel M, Nöthen MM, Cichon S.  Genome-wide association data provide further support for an association between 5-HTTLPR and major depressive disorder.  J Affect Disord. 2013 Apr 25;146(3):438-40.

2426 Hagemann A, May TW, Nieder E, Witte-Bölt K, Pohlmann-Eden B, Elger CE, Tergau F, Schulze-Bonhage A, Straub HB, Arnold S, Brandt C. Quality of life, anxiety and depression in adult patients after add-on of levetiracetam and conversion to levetiracetam monotherapy. Epilepsy Res. 2013 Mar;104(1-2):140-50. doi: 10.1016/j.eplepsyres.2012.08.005. Epub 2012 Sep 6. PMID:22959715.

2425 Hämmerer D, Biele G, Müller V, Thiele H, Nürnberg P, Heekeren HR, Li SC.  Effects of PPP1R1B (DARPP-32) Polymorphism on Feedback-Related Brain Potentials Across the Life Span.  Front Psychol. 2013;4:89. doi: 10.3389/fpsyg.2013.00089. Epub 2013 Mar 4.

2424 Hauer K, Calzada-Wack J, Steiger K, Grunewald TG, Baumhoer D, Plehm S, Buch T, Prazeres da Costa O, Esposito I, Burdach S, Richter GH.  DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma.  Cancer Res. 2013 Jan 15;73(2):967-77. doi: 10.1158/0008-5472.

2423 Hauer K., Julia Calzada?Wack, Frauke Neff, Annette Fasan, Irene Esposito, Stefan Burdach and Günther HS Richter.  BRICHOS genes CHM1 and ITM2A control osteolysis and maintain an undifferentiated, invasive phenotype in Ewing sarcoma.  Frontiers in Oncology ISSN: 2234-943X in press.

2422 Hebebrand J, Hinney A, Knoll N, Volckmar AL, Scherag A. Molekulargenetische Aspekte der Körpergewichtsregulation. Dtsch Arztebl Int 2013; 110(19): 338-44.

2421 Heckman JA, Bardien S, Bozi M, Brice A, Brighina L , Van Broeckhoven C, Carr J, Chartier-Harlin MC, Dardiotis E , Dennis W. Dickson MD 2 , Diehl NN, Elbaz A , Ferrarese C , Ferraris A, Fiske B , Gibson J , Gibson R, Hadjigeorgiou GM,  Hattori N , Ioannidis JPA , Jasinska-Myga B, Jeon BS, Kim YJ, Klein C, Krüger R, Kyratzi  E, Lesage S, Lin CH, Lynch T,  Maraganore DMM, Mellick G, Mutez E,  Nilsson C, Opala G, Park SS, Puschmann A, Quattrone A, Sharma M,  Silburn PA,  Sohn  YA,  Stefanis L, Tadic J,  Theuns J, Tomiyama H , Uitti RJ, Valente EM,  van de Loo S, Vassilatis DK, Vilariño-Güell  C, White LR, Wirdefelt K, Wszolek ZK , Wu RM, Farrer MJ Ross OA on behalf of the Genetic Epidemiology Of Parkinson?s Disease (GEO-PD) consortium.  Population-specific frequencies for LRRK2 susceptibility variants.  Mov Disord (in press)

2420 Heinrich A, Lourdusamy A, Tzschoppe J, Vollstädt-Klein S, Bühler M, Steiner S, Bach C, Poustka L, Banaschewski T, Barker G, Büchel C, Conrod P, Garavan H, Gallinat J, Heinz A, Ittermann B, Loth E, Mann K, Martinot JL, Paus T, Pausova Z, Smolka M, Ströhle A, Struve M, Witt S, Flor H, Schumann G, Rietschel M, Nees F.  The risk variant in ODZ4 for bipolar disorder impacts on amygdala activation during reward processing.  Bipolar Disord. 2013 Apr 24. doi: 10.1111/bdi.12068.[Epub ahead of print]

2419 Heinrich A, Nees F, Lourdusamy A, Tzschoppe J, Meier S, Vollstädt-Klein S,Fauth-Bühler M, Steiner S, Bach C, Poustka L, Banaschewski T, Barker GJ, Büchel C, Conrod PJ, Garavan H, Gallinat J, Heinz A, Ittermann B, Loth E, Mann K, Artiges E, Paus T, Lawrence C, Pausova Z, Smolka MN, Ströhle A, Struve M, Witt SH, Schumann G, Flor H, Rietschel M; The IMAGEN consortium.  From gene to brain to behavior: schizophrenia-associated variation in AMBRA1 alters impulsivity-related traits.  Eur J Neurosci. 2013 Apr 2. doi: 10.1111/ejn.12201. [Epub ahead of print]

2418 Helmstaedter C, Mihov Y, Toliat MR, Thiele H, Nuernberg P, Schoch S, Surges R, Elger CE, Kunz WS, Hurlemann R.  Genetic variation in dopaminergic activity is associated with the risk for psychiatric side effects of levetiracetam.  Epilepsia. 2013 Jan;54(1):36-44. doi: 10.1111/j.1528-1167.2012.03603.x. Epub 2012 Aug 6.

2417 Helwig M, Herwig A, Heldmaier G, Barrett P, Mercer JG, Klingenspor M.  Photoperiod-dependent regulation of carboxypeptidase E affects the selective processing of neuropeptides in the seasonal Siberian hamster (Phodopus sungorus).  J Neuroendocrinol. 2013 Feb;25(2):190-7. doi: 10.1111/j.1365-2826.2012.02384.

2416 Herold C, Mattheisen M, Lacour A, Vaitsiakhovich T, Angisch M, Drichel D, Becker T.  Integrated genome-wide pathway association analysis with INTERSNP.  Hum Hered. 2012;73(2):63-72. doi: 10.1159/000336196.

2415 Hochrath K, Ehnert S, Ackert-Bicknell CL, Lau Y, Schmid A, Krawczyk M,Hengstler JG, Dunn J, Hiththetiya K, Rathkolb B, Micklich K, Hans W, Fuchs H,Gailus-Durner V, Wolf E, de Angelis MH, Dooley S, Paigen B, Wildemann B, Lammert F, Nüssler AK.  Modeling hepatic osteodystrophy in Abcb4 deficient mice.  Bone. 2013 Mar 29. doi:pii: S8756-3282(13)00129-4. 10.1016/j.bone.2013.03.012. [Epubahead of print] PubMed PMID: 23545228.

2414 Hoe, C. H., Raabe, C.A., Rozhdestvensky, T.F., Tang, T.H.  Bacterial sRNAs: Regulation in stress.  Int J Med Microbiol. 2013 Jul;303(5):217-29. doi: 10.1016/j.ijmm.2013.04.002. Epub 2013 Apr 11.
PMID:23660175[PubMed - in process]

2413 Hoffmann S, Berger IM, Glaser A, Bacon C, Li L, Gretz N, Steinbeisser H, Rottbauer W, Just S, Rappold G (2013)  Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia.  Basic Res Cardiol 108:339 doi:10.1007/s00395-013-0339-z.

2412 Hoheisel, J.D., Alhamdani, M.S.S. & Schröder, C. Affinity-based microarrays for proteomic analysis of cancer tissues.  Proteomics Clin. Appl. 7, 8-16. 

2411 Holland JD, Klaus A, Garratt AN, Birchmeier W.  Wnt signaling in stem and cancer stem cells.  Curr Opin Cell Biol. 2013, 2, 254-264 (NGFNPlus acknowledged).

2410 Holmans P, Moskvina V, Jones L, Sharma M; International Parkinson's Disease Genomics Consortium, Vedernikov A, Buchel F, Sadd M, Bras JM, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton AB, Nalls MA, Hardy J, Morris HR, Williams NM.  A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.  Human Molecular Genetics 2013 Mar 1;22(5):1039-49. doi: 10.1093/hmg/dds492.

2409 Holmqvist E, Vogel J. A small RNA serving both the Hfq and CsrA regulons Genes & Development 27:1073-1078

2408 Holzhauser S, Freiwald A, Weise C, Multhaup G, Han CT, Sauer S.  Discovery and Characterization of Protein-Modifying Natural Products by MALDI Mass Spectrometry Reveal Potent SIRT1 and p300 Inhibitors.  Angew Chem Int Ed Engl. 2013 May 3;52(19):5171-4.

2407  Hovestadt V, Remke M, Kool M, Pietsch T, Northcott PA, Fischer R, Cavalli FM, Ramaswamy V, Zapatka M, Reifenberger G, Rutkowski S, Schick M, Bewerunge-Hudler M, Korshunov A, Lichter P, Taylor MD, Pfister SM, Jones DT. Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays.  Acta Neuropathol. 2013 Jun;125(6):913-6. doi: 10.1007/s00401-013-1126-5.

2406 Huan T, Zhang B, Wang Z, Joehanes R, Zhu J, Johnson AD, Ying S, Munson PJ, Raghavachari N, Wang R, Liu P, Courchesne P, Hwang SJ, Assimes TL, McPherson R, Samani NJ, Schunkert H; Coronary ARteryDIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) Consortium, International Consortium for Blood Pressure GWAS (ICBP), Meng Q, Suver C, O'Donnell CJ, Derry J, Yang X, Levy D. A  Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease.  Arterioscler Thromb Vasc Biol. 2013 Mar 28. [Epub ahead of print] PubMed PMID: 23539213.

2405  Issa A, Gill JW, Heideman MR, Sahin O, Wiemann S, Dey JH, Hynes NE:  Combinatorial targeting of FGF and ErbB receptors blocks growth and metastatic spread of breast cancer models.  Breast Cancer Res 2013, 15(1):R8.

2404 Jaiswal M, Dvorsky R, Ahmadian MR. Deciphering the Molecular and Functional Basis of Dbl Family Proteins: A NOVEL SYSTEMATIC APPROACH TOWARD CLASSIFICATION OF SELECTIVE ACTIVATION OF THE Rho FAMILY PROTEINS.  J Biol Chem 288, 4486-4500. PMID: 23255595.

2403 Jing, L., Chong, T.M., Bruckner, J., Davies, D.H., Felgner, P.L., Wald, A., Haas, J., Verjans, G.M.G.M., Koelle, D.M. Memory CD4 T-cell responses in humans are independent of pathogen persistence and show prolonged maintenance of subdominant specificities. J Immunol. in press.

2402 Jones DTW, Hutter B, Jäger N, Korshunov A, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM. Recurrent FGFR1 hotspot mutations represent a novel therapeutic target in childhood astrocytoma.  Nat Genetics 2013 (accepted)

2401 Ju L, Wing J, Taylor E, Brandt R, Slijepcevic P, Horsch M, Rathkolb B, Rácz I, Becker L, Hans W, Adler T, Beckers J, Rozman J, Klingenspor M, Wolf E, Zimmer A, Klopstock T, Busch DH, Gailus-Durner V, Fuchs H, de Angelis MH, van der Horst G, Lehmann AR.   SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities. DNA Repair (Amst). 2013 May 1;12(5):356-66. doi: 10.1016/j.dnarep.2013.02.006.

2400 Judy JT, Seifuddin F, Pirooznia M, Mahon PB; Bipolar Genome Study Consortium, Jancic D, Goes FS, Schulze T, Cichon S, Noethen M, Rietschel M, Depaulo JR Jr, Potash JB, Zandi PP.  Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder.  Front Genet. 2013 May 17;4:87.

2399 Kacprowski T, Doncheva NT, Albrecht M.  NetworkPrioritizer: A versatile tool for network-based prioritization of candidate disease genes or other molecules.  Bioinformatics. 2013 Jun 1;29(11):1471-3.

2398 Kallenborn-Gerhardt W, Lu R, Syhr KM, Heidler J, von Melchner H, Geisslinger G, Bangsow T, Schmidtko A.  Antioxidant activity of Sestrin 2 controls neuropathic pain after peripheral nerve injury.  Antioxid Redox Signal. 2013 Epub ahead of print.

2397 Kamburov A, Stelzl U, Lehrach H, Herwig R.  The ConsensusPathDB interaction database: 2013 update.  Nucleic Acids Research, 2013; 41(Database issue):D793-800.

2396 Kamburov A, Stelzl U, Lehrach H, Herwig R.  The ConsensusPathDB interactiondatabase: 2013 update.  Nucleic Acids Res. 2013 Jan;41(Database issue):D793-800.

2395 Kappei D, Butter F, Benda C, Scheibe M, Dra?kovi? I, Stevense M, Novo CL, Basquin C, Araki M, Araki K, Krastev DB, Kittler R, Jessberger R, Londoño-Vallejo JA, Mann M, Buchholz F. HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment.  EMBO J. 2013 May 17. doi: 10.1038/emboj.2013.105.

2394 Keshav S, Va?ásek T, Niv Y, Petryka R, Howaldt S, Bafutto M, Rácz I, Hetzel D, Nielsen OH, Vermeire S, Reinisch W, Karlén P, Schreiber S, Schall TJ, Bekker P; Prospective Randomized Oral-Therapy Evaluation in Crohn?s Disease Trial-1 (PROTECT-1) Study Group A Randomized Controlled Trial of the Efficacy and Safety of CCX282-B, an Orally-Administered Blocker of Chemokine Receptor CCR9, for Patients with Crohn's Disease.<http://www.ncbi.nlm.nih.gov/pubmed/23527300>. PLoS One. 2013;8(3):e60094. doi: 10.1371/journal.pone.0060094. Epub 2013 Mar 20.

2393 Kieckbusch K, Beckers A, Odersky A, Mestdagh P, Köster J, Bray IM, Bryan K, Vandesompele J, Speleman F, Stallings RL, Schramm A, Eggert A, Sprüssel A, Schulte JH. MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.  Int J Cancer. 2013 Feb 7. doi: 10.1002/ijc.28091.

2392 Kienast T, Schlagenhauf F, Rapp M, Wrase J, Daig I, Buchholz HG, Smolka MN, Gründer G, Kumakura Y, Cumming P, Charlet K, Bartenstein P, Hariri A, Heinz A. Dopamine-modulated aversive emotion processing fails in alcohol-dependent patients.  Pharmacopsychiatry. 2013 Jun;46(4):130-6. doi: 10.1055/s-0032-1331747. Epub 2013 Jan 30.

2391 Klebe S, Golmard JL, Nalls M, Saad M, Singleton A, Bras J, Hardy J, Simon-Sanchez J, Heutink P, Kuhlenbäumer G, Charfi R, Klein C, Hagenah J, Gasser T, Wurster I, Lesage S, Lorenz D, Deuschl G, Durif F, Pollak P, Damier P, Tison F, Durr A, Amouyel P, Lambert JC, Tzourio C, Maubaret C, Charbonnier-Beaupel F, Tahiri K, Vidailhet M, Martinez M, Brice A, Corvol JC.  Impact of COMT rs4680 on age at onset in Parkinson Disease.  J Neurol Neurosurg Psychiatry, Epub ahead of print.


2390 Knoll N, Jarick I, Volckmar AL, Klingenspor M, Illig T, Grallert H, Gieger C, Wichmann HE, Peters A, Hebebrand J, Scherag A, Hinney A.  Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity.  PLoS One. 2013; 8(2): e55884. doi: 10.1371/journal.pone.0055884.

2389  Kocak H, Ackermann S, Hero B, Kahlert Y, Oberthuer A, Juraeva D, Roels F,Theissen J, Westermann F, Deubzer H, Ehemann V, Brors B, Odenthal M, Berthold F, Fischer M.  Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma.  Cell Death Dis. 2013 Apr 11;4:e586.

2388 Kornblum C, Nicholls TJ, Haack TB, Schöler S, Peeva V, Danhauser K, Hallmann K, Zsurka G, Rorbach J, Iuso A, Wieland T, Sciacco M, Ronchi D, Comi GP, Moggio M, Quinzii CM, DiMauro S, Calvo SE, Mootha VK, Klopstock T, Strom TM, Meitinger T, Minczuk M, Kunz WS, Prokisch H. Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. Nat Genet. 2013 Feb;45(2):214-9.

2387 Körner C, Keklikoglou I, Bender C, Wörner A, Münstermann E, Wiemann S:  microRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C epsilon (PKC{varepsilon}).  J Biol Chem 2013:Epub.

2386 Köttgen A, Albrecht E, Teumer A, Vitart V, Krumsiek J, Hundertmark C, Pistis G, Ruggiero D, O'Seaghdha CM, Haller T, Yang Q, Tanaka T, Johnson AD, Kutalik Z, Smith AV, Shi J, Struchalin M, Middelberg RP, Brown MJ, Gaffo AL, Pirastu N, Li G, Hayward C, Zemunik T, Huffman J, Yengo L, Zhao JH, Demirkan A, Feitosa MF, Liu X, Malerba G, Lopez LM, van der Harst P, Li X, Kleber ME, Hicks AA, Nolte IM, Johansson A, Murgia F, Wild SH, Bakker SJ, Peden JF, Dehghan A, Steri M, Tenesa A, Lagou V, Salo P, Mangino M, Rose LM, Lehtimäki T, Woodward OM, Okada Y, Tin A, Müller C, Oldmeadow C, Putku M, Czamara D, Kraft P, Frogheri L, Thun GA, Grotevendt A, Gislason GK, Harris TB, Launer LJ, McArdle P, Shuldiner AR, Boerwinkle E, Coresh J, Schmidt H, Schallert M, Martin NG, Montgomery GW, Kubo M, Nakamura Y, Tanaka T, Munroe PB, Samani NJ, Jacobs DR Jr, Liu K, D'Adamo P, Ulivi S, Rotter JI, Psaty BM, Vollenweider P, Waeber G, Campbell S, Devuyst O, Navarro P, Kolcic I, Hastie N, Balkau B, Froguel P, Esko T, Salumets A, Khaw KT, Langenberg C, Wareham NJ, Isaacs A, Kraja A, Zhang Q, Wild PS, Scott RJ, Holliday EG, Org E, Viigimaa M, Bandinelli S, Metter JE, Lupo A, Trabetti E, Sorice R, Döring A, Lattka E, Strauch K, Theis F, Waldenberger M, Wichmann HE, Davies G, Gow AJ, Bruinenberg M; LifeLines Cohort Study, Stolk RP, Kooner JS, Zhang W, Winkelmann BR, Boehm BO, Lucae S, Penninx BW, Smit JH, Curhan G, Mudgal P, Plenge RM, Portas L, Persico I, Kirin M, Wilson JF, Mateo Leach I, van Gilst WH, Goel A, Ongen H, Hofman A, Rivadeneira F, Uitterlinden AG, Imboden M, von Eckardstein A, Cucca F, Nagaraja R, Piras MG, Nauck M, Schurmann C, Budde K, Ernst F, Farrington SM, Theodoratou E, Prokopenko I, Stumvoll M, Jula A, Perola M, Salomaa V, Shin SY, Spector TD, Sala C, Ridker PM, Kähönen M, Viikari J, Hengstenberg C, Nelson CP; CARDIoGRAM Consortium; DIAGRAM Consortium; ICBP Consortium; MAGIC Consortium, Meschia JF, Nalls MA, Sharma P, Singleton AB, Kamatani N, Zeller T, Burnier M, Attia J, Laan M, Klopp N, Hillege HL, Kloiber S, Choi H, Pirastu M, Tore S, Probst-Hensch NM, Völzke H, Gudnason V, Parsa A, Schmidt R, Whitfield JB, Fornage M, Gasparini P, Siscovick DS, Pola?ek O, Campbell H, Rudan I, Bouatia-Naji N, Metspalu A, Loos RJ, van Duijn CM, Borecki IB, Ferrucci L, Gambaro G, Deary IJ, Wolffenbuttel BH, Chambers JC, März W, Pramstaller PP, Snieder H, Gyllensten U, Wright AF, Navis G, Watkins H, Witteman JC, Sanna S, Schipf S, Dunlop MG, Tönjes A, Ripatti S, Soranzo N, Toniolo D, Chasman DI, Raitakari O, Kao WH, Ciullo M, Fox CS, Caulfield M, Bochud M, Gieger C.  Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.  Nat Genet. 2013 Feb;45(2):145-54.

2385 Kragh CL, Fillon G, Gysbers A, Hansen HD, Neumann M, Richter-Landsberg C, Haass C, Zalc B, Lubetzki C, Gai WP, Halliday GM, Kahle PJ, Jensen PH.  FAS-dependent cell death in ?-synuclein transgenic oligodendrocyte models of multiple system atrophy.  PLoS One. 2013;8(1):e55243.

2384 Kreck B et al. (2013)   Base-pair resolution DNA methylome of the EBV-positive Endemic Burkitt lymphoma cell line DAUDI determined by SOLiD bisulfite-sequencing. Leukemia.doi: 10.1038/leu.2013.4. [Epub ahead of print].

2383 Kreiner G, Bierhoff H, Armentano M, Rodriguez Parkitna J, Bonfanti L, Grummt I, Schütz G, Parlato R.  A neuroprotective phase precedes striatal degeneration upon nucleolar stress Cell Death Differ. 2013 Jun 14. doi: 10.1038/cdd.2013.66. [Epub ahead of print].

2382 Krentz S, Hof J, Mendioroz A, Vaggopoulou R, Dörge P, Lottaz C, Engelmann JC, Groeneveld TW, Körner G, Seeger K, Hagemeier C, Henze G, Eckert C, von Stackelberg A, and Kirschner-Schwabe R.  Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia.  Leukemia 2013 Feb;27(2):295-304. doi: 10.1038/leu.2012.155. Epub 2012 Jun 13.

2381 Kugler JE, Horsch M, Huang D, Furusawa T, Rochman M, Garrett L, Becker L,Bohla A, Holter SM, Prehn C, Rathkolb B, Racz I, Aguilar-Pimentel JA, Adler T,Adamski J, Beckers J, Busch DH, Eickelberg O, Klopstock T, Ollert M, Stoeger T,Wolf E, Wurst W, Yildirim AO, Zimmer A, Gailus-Durner V, Fuchs H, Hrabe deAngelis M, Garfinkel B, Orly J, Ovcherenko I, Bustin M.  High mobility group N (HMGN) proteins modulate the fidelity of the cellular transcriptional profile in a tissue and variant specific manner.  J Biol Chem. 2013 Apr 24. [Epub ahead of print] PubMed PMID:23620591.

2380 Kumar K, Ramirez A, Göbel A, Kresojevic N, Svetel M, Lohmann K, Sue CM, Rolfs A, Mazzulli JR, Alcalay RN, Krainc D, Klein C, Kostic V, Grünewald A.  Glucocerebrosidase mutations in a Serbian Parkinson?s disease population.  Eur J Neurol 2013;20:402-405.

2379 Kumps C, Fieuw A, Mestdagh P, Menten B, Lefever S, Pattyn F, De Brouwer S,Sante T, Schulte JH, Schramm A, Van Roy N, Van Maerken T, Noguera R, Combaret V, Devalck C, Westermann F, Laureys G, Eggert A, Vandesompele J, De Preter K, Speleman F.  Focal DNA copy number changes in neuroblastoma target MYCN regulated genes.  PLoS One. 2013;8(1):e52321. doi: 10.1371/journal.pone.0052321. Epub 2013 Jan 4. PubMed PMID: 23308108; PubMed Central PMCID: PMC3537730.

2378 Ladewig, J.*, Koch, P.*, Brüstle, O. (2013) Leveling Waddington: the emergence of direct programming and the loss of cell fate hierarchies. Nat Rev Mol Cell Biol doi:10.1038/nrm3543.

2377 Lal D et al. Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy. Epilepsia. 2013;54:265-71.

2376 Lal D, Trucks H, Møller RS, Hjalgrim H, Koeleman BP, de Kovel CG, Visscher F, Weber YG, Lerche H, Becker F, Schankin CJ, Neubauer BA, Surges R, Kunz WS, Zimprich F, Franke A, Illig T, Ried JS, Leu C, Nürnberg P, Sander T; EMINet Consortium; EPICURE Consortium.  Rare exonic deletions of the RBFOX1 gene increase risk of idiopathic generalized epilepsy.  Epilepsia. 2013;54:265-71.

2375 Lambert JC, Grenier-Boley B, Harold D, Zelenika D, Chouraki V, Kamatani Y, Sleegers K, Ikram MA, Hiltunen M, Reitz C, Mateo I, Feulner T, Bullido M, Galimberti D, Concari L, Alvarez V, Sims R, Gerrish A, Chapman J, Deniz-Naranjo C, Solfrizzi V, Sorbi S, Arosio B, Spalletta G, Siciliano G, Epelbaum J, Hannequin D, Dartigues JF, Tzourio C, Berr C, Schrijvers EM, Rogers R, Tosto G, Pasquier F, Bettens K, Van Cauwenberghe C, Fratiglioni L, Graff C, Delepine M, Ferri R, Reynolds CA, Lannfelt L, Ingelsson M, Prince JA, Chillotti C, Pilotto A, Seripa D, Boland A, Mancuso M, Bossù P, Annoni G, Nacmias B, Bosco P, Panza F, Sanchez-Garcia F, Del Zompo M, Coto E, Owen M, O'Donovan M, Valdivieso F, Caffara P, Scarpini E, Combarros O, Buée L, Campion D, Soininen H, Breteler M, Riemenschneider M, Van Broeckhoven C, Alpérovitch A, Lathrop M, Trégouët DA, Williams J, Amouyel P.  Genome-wide haplotype association study identifies the FRMD4A gene as a risk locus for Alzheimer's disease. Molecular Psychiatry 2013;18, 461-470.  [Epub 2012].

2374  Lankisch P, H. Adler and A. Borkhardt Testing for herpesvirus infection is essential in children with chromosomal-instability syndromes.  J of Virology, 87 (2013): 3616-3617.

2373 Lascorz J, Bevier M, V Schönfels W, Kalthoff H, Aselmann H, Beckmann J, Egberts J, Buch S, Becker T, Schreiber S, Hampe J, Hemminki K, Schafmayer C, Försti A.  Association study identifying polymorphisms in CD47 and other extracellular matrix pathway genes as putative prognostic markers for colorectal cancer.  Int J Colorectal Dis 2013;28(2):173-81. doi: 10.1007/s00384-012-1541-4.

2372 Lausser L, Müssel C, Maucher M, Kestler HA.  Measuring and visualizing the stability of biomarker selection techniques.  Computational Statistics. 2013; 28(1):51-65.

2371 Lavebratt C, Olsson S, Backlund L, Frisén L, Sellgren C, Priebe L, Nikamo P, Träskman-Bendz L, Cichon S, Vawter MP, Osby U, Engberg G, Landén M, Erhardt S, Schalling M.  The KMO allele encoding Arg<sup>452</sup> is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression.  Mol Psychiatry. 2013 Mar 5. doi: 10.1038/mp.2013.11.

2370 Lee SG, Cho SY, Kim MJ, Oh SH, Cho EH, Lee S, Baek EJ, Choi JH, Bohlander SK, Lode L, Richebourg S, Yoon HJ, Marschalek R, Meyer C, Park TS.  Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias.  Haematologica. 2013;98:e55-e57.

2369 Lenac Roviš T, Bailer SM, Pothineni VR, Ouwendijk WJ, Šimi? H, Babi? M, Mikli? K, Mali? S, Verweij MC, Baiker A, Gonzalez O, von Brunn A, Zimmer R, Früh K, Verjans GM, Jonji? S, Haas J. A comprehensive analysis of Varicella Zoster virus (VZV) proteins using a monoclonal antibody collection.  J Virol In press

2368 Lennertz L, Franke PE, Grabe HJ, Rampacher F, Schulze-Rauschenbach S, Guttenthaler V, Ruhrmann S, Pukrop R, Klosterkötter J, Falkai P, Maier W, Wagner M, Mössner R The functional coding variant Asn107Ile of the neuropeptide S receptor gene (NPSR1) influences age at onset of obsessive-compulsive disorder. Int J Neuropsychopharmacol im Druck.

2367 Levinson DF, Shi J, Wang K, Oh S, Riley B, Pulver AE, Wildenauer DB, Laurent C, Mowry BJ, Gejman PV, Owen MJ, Kendler KS, Nestadt G, Schwab SG, Mallet J, Nertney D, Sanders AR, Williams NM, Wormley B, Lasseter VK, Albus M, Godard-Bauché S, Alexander M, Duan J, O'Donovan MC, Walsh D, O'Neill A, Papadimitriou GN, Dikeos D, Maier W, Lerer B, Campion D, Cohen D, Jay M, Fanous A, Eichhammer P, Silverman JM, Norton N, Zhang N, Hakonarson H, Gao C, Citri A, Hansen M, Ripke S; Schizophrenia Psychiatric GWAS Consortium (Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L, Visscher PM, Posthuma D, Ruderfer DM, Fanous A, Stefansson H, Steinberg S, Mowry BJ, Golimbet V, De Hert M, Jönsson EG, Bitter I, Pietiläinen OP, Collier DA, Tosato S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bergen SE, Black DW, Børglum AD, Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger CR, Cormican P, Craddock N, Danoy PA, Datta S, de Haan L, Demontis D, Dikeos D, Djurovic S, Donnelly P, Donohoe G, Duong L, Dwyer S, Fink-Jensen A, Freedman R, Freimer NB, Friedl M, Georgieva L, Giegling I, Gill M, Glenthøj B, Godard S, Hamshere M, Hansen M, Hansen T, Hartmann AM, Henskens FA, Hougaard DM, Hultman CM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jürgens G, Kahn RS, Keller MC, Kenis G, Kenny E, Kim Y, Kirov GK, Konnerth H, Konte B, Krabbendam L, Krasucki R, Lasseter VK, Laurent C, Lawrence J, Lencz T, Lerer FB, Liang KY, Lichtenstein P, Lieberman JA, Linszen DH, Lönnqvist J, Loughland CM, Maclean AW, Maher BS, Maier W, Mallet J, Malloy P, Mattheisen M, Mattingsdal M, McGhee KA, McGrath JJ, McIntosh A, McLean DE, McQuillin A, Melle I, Michie PT, Milanova V, Morris DW, Mors O, Mortensen PB, Moskvina V, Muglia P, Myin-Germeys I, Nertney DA, Nestadt G, Nielsen J, Nikolov I, Nordentoft M, Norton N, Nöthen MM, O'Dushlaine CT, Olincy A, Olsen L, O'Neill FA, Orntoft TF, Owen MJ, Pantelis C, Papadimitriou G, Pato MT, Peltonen L, Petursson H, Pickard B, Pimm J, Pulver AE, Puri V, Quested D, Quinn EM, Rasmussen HB, Réthelyi JM, Ribble R, Rietschel M, Riley BP, Ruggeri M, Schall U, Schulze TG, Schwab SG, Scott RJ, Shi J, Sigurdsson E, Silverman JM, Spencer CC, Stefansson K, Strange A, Strengman E, Stroup TS, Suvisaari J, Terenius L, Thirumalai S, Thygesen JH, Timm S, Toncheva D, van den Oord E, van Os J, van Winkel R, Veldink J, Walsh D, Wang AG, Wiersma D, Wildenauer DB, Williams HJ, Williams NM, Wormley B, Zammit S, Sullivan PF, O'Donovan MC, Daly MJ, Gejman PV), Dudbridge F, Holmans PA.  Genome-wide association study of multiplex schizophrenia pedigrees.  Am J Psychiatry 2012;169:963-973. Doi: 10.1176/appi.ajp.2012.11091423.

2366 Li M, Luo XJ, Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Arias Vasquez A, Hibar DP, Franke B,  Martin NG, Wright MJ; MooDS Bipolar Consortium, Strohmaier J, Breuer R, Meier S, Mühleisen TW, Degenhardt FA, Hoffmann P, Herms S, Schwarz M, Vedder H, Kammerer-Ciernioch J, Reif A, Sasse J, Bauer M, Zwick S, Hautzinger M, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Martin NG, Czerski PM, Hauser J, Schumacher J, Maier W, Propping P; The Swedish Bipolar Study Group, Backlund L, Frisén L, Lavebratt C, Schalling M, Osby U; The Alzheimer?s Disease Neuroimaging Initiative; ENIGMA Consortium; CHARGE Consortium, Su B.  Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility.  Mol Psychiatry. 2013 Apr 9. doi: 10.1038/mp.2013.37. [Epub ahead of print].

2365 Li Z, Herold T, He C, Valk PJ, Chen P, Jurinovic V, Mansmann U, Radmacher MD, Maharry KS, Sun M, Yang X, Huang H, Jiang X, Sauerland MC, Büchner T, Hiddemann W, Elkahloun A, Neilly MB, Zhang Y, Larson RA, Le Beau MM, Caligiuri MA, Döhner K, Bullinger L, Liu PP, Delwel R, Marcucci G, Lowenberg B, Bloomfield CD, Rowley JD, Bohlander SK, Chen J.  Identification of a 24-Gene Prognostic Signature That Improves the European LeukemiaNet Risk Classification of Acute Myeloid Leukemia: An International Collaborative Study.  J Clin Oncol. 2013;31:1172-1181.

2364 Lieb W, Jansen H, Loley C, Pencina MJ, Nelson CP, Newton-Cheh C, Kathiresan S, Reilly MP, Assimes TL, Boerwinkle E, Hall AS, Hengstenberg C, Laaksonen R, McPherson R, Thorsteinsdottir U, Ziegler A, Peters A, Thompson JR, König IR, Erdmann J, Samani NJ, Vasan RS, Schunkert H; on behalf of CARDIoGRAM.  Genetic Predisposition to Higher Blood Pressure Increases Coronary Artery Disease Risk.  Hypertension. 2013 Mar 11. [Epub ahead of print] PubMed PMID: 23478099.

2363 Liedén A, Winge MC, Sääf A, Kockum I, Ekelund E, Rodriguez E, Fölster-Holst R, Franke A, Illig T, Tengvall-Linder M, Baurecht H, Weidinger S, Wahlgren CF, Nordenskjöld M, Bradley M.  Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.  PLoS One 2012; 7:e49694.

2362 Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Srivastava B, Dalekos G, Nöthen MM, Herms S, Winkelmann J, Mitrovic M, Braun F, Ponsioen CY, Croucher PJ, Sterneck M, Teufel A, Mason AL, Saarela J, Leppa V, Dorfman R, Alvaro D, Floreani A, Onengut-Gumuscu S, Rich SS, Thompson WK, Schork AJ, Næss S, Thomsen I, Mayr G, König IR, Hveem K, Cleynen I, Gutierrez-Achury J, Ricaño-Ponce I, van Heel D, Björnsson E, Sandford RN, Durie PR, Melum E, Vatn MH, Silverberg MS, Duerr RH, Padyukov L, Brand S, Sans M, Annese V, Achkar JP, Boberg KM, Marschall HU, Chazouillères O, Bowlus CL, Wijmenga C, Schrumpf E, Vermeire S, Albrecht M; UK-PSCSC Consortium; International IBD Genetics Consortium, Rioux JD, Alexander G, Bergquist A, Cho J, Schreiber S, Manns MP, Färkkilä M, Dale AM, Chapman RW, Lazaridis KN; International PSC Study Group, Franke A, Anderson CA, Karlsen TH.  Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.  Nat Genet. 2013 Apr 21;45(6):670-5.

2361 LLudwig, K. U., P. Samann, M. Alexander, J. Becker, J. Bruder, K. Moll, D. Spieler, M. Czisch, A. Warnke, S. J. Docherty, O. S. Davis, R. Plomin, M. M. Nothen, K. Landerl, B. Muller-Myhsok, P. Hoffmann, J. Schumacher, G. Schulte-Korne, and D. Czamara.  A common variant in Myosin-18B contributes to mathematical abilities in children with dyslexia and intraparietal sulcus variability in adults.  Transl Psychiatry. 2013 Feb 19;3:e229. doi: 10.1038/tp.2012.148..

2360 Lodrini M, Oehme I, Schroeder C, Milde T, Schier MC, Kopp-Schneider A, Schulte JH, Fischer M, De Preter K, Pattyn F, Castoldi M, Muckenthaler MU, Kulozik AE, Westermann F, Witt O, Deubzer HE.  MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma. Nucleic Acids Res. 2013 Apr 26. [Epub ahead of print].

2359  Loedige I., Gaidatzis D., Sack R., Meister G. & Filipowicz W. The mammalian TRIM-NKL protein Trim71/LIN41 is a repressor of mRNA function.  Nucleic Acids Research, 1(2):141-55.

2358 Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigur.  A mega-analysis of genome-wide association studies for major depressive disorder.  Mol Psychiatry. 2013 Apr;18(4):497-511.

2357 Mäkelä KM, Seppälä I, Hernesniemi JA, Lyytikäinen LP, Oksala N, Kleber ME, Scharnagl H, Grammer TB, Baumert J, Thorand B, Jula A, Hutri-Kähönen N, Juonala M, Laitinen T, Laaksonen R, Karhunen PJ, Nikus KC, Nieminen T, Laurikka J, Kuukasjärvi P, Tarkka M, Viik J, Klopp N, Illig T, Kettunen J, Ahotupa M, Viikari JS, Kähönen M, Raitakari OT, Karakas M, Koenig W, Boehm BO, Winkelmann BR, März W, Lehtimäki T. Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events: AtheroRemo Consortium. Circ Cardiovasc Genet 2013;6:73-81.

2356 Martinelli-Boneschi F, Giacalone G, Magnani G, Biella G, Coppi E, Santangelo R, Brambilla P, Esposito F, Lupoli S, Clerici F, Benussi L, Ghidoni R, Galimberti D, Squitti R, Confaloni A, Bruno G, Pichler S, Mayhaus M, Riemenschneider M, Mariani C, Comi G, Scarpini E, Binetti G, Forloni G, Franceschi M, Albani D.  Pharmacogenomics in Alzheimer's disease: a genome-wide association study of response to cholinesterase inhibitors.  Neurobiol Aging. 2013;34(6):1711.e7-13. [Epub 2013].

2355 Mattheisen M, Mühleisen TW, Strohmaier J, Treutlein J, Nenadic I, Alblas M, Meier S, Degenhardt F, Herms S, Hoffmann P, Witt SH, Giegling I, Sauer H, Schulze TG, Rujescu D, Nöthen MM, Rietschel M, Cichon S.  Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia.  Schizophr Res. 2012 Nov;141(2-3):262-5. doi: 10.1016/j.schres.2012.08.027.

2354 Meier S, Strohmaier J, Breuer R, Mattheisen M, Degenhardt F, Mühleisen TW, Schulze TG, Nöthen MM, Cichon S, Rietschel M, Wüst S.  Neuregulin 3 is associated with attention deficits in schizophrenia and bipolar disorder.  Int J Neuropsychopharmacol. 2013 Apr;16(3):549-56. doi: 10.1017/S1461145712000697.

2353 Meinhardt MW, Hansson AC, Perreau-Lenz S, Bauder-Wenz C, Stählin O, Heilig M, Harper C, Drescher KU, Spanagel R, Sommer WH.  Rescue of Infralimbic mGluR2 Deficit Restores Control Over Drug-Seeking Behavior in Alcohol Dependence.  J Neurosci. 2013 Feb 13;33(7):2794-806.

2352 Melén E, Granell R, Kogevinas M, Strachan D, Gonzalez JR, Wjst M, Jarvis D,Ege M, Braun-Fahrländer C, Genuneit J, Horak E, Bouzigon E, Demenais F, KauffmannF, Siroux V, Michel S, von Berg A, Heinzmann A, Kabesch M, Probst-Hensch NM,Curjuric I, Imboden M, Rochat T, Henderson J, Sterne JA, McArdle WL, Hui J, JamesAL, William Musk A, Palmer LJ, Becker A, Kozyrskyj AL, Chan-Young M, Park JE,Leung A, Daley D, Freidin MB, Deev IA, Ogorodova LM, Puzyrev VP, Celedón JC,Brehm JM, Cloutier MM, Canino G, Acosta-Pérez E, Soto-Quiros M, Avila L,Bergström A, Magnusson J, Söderhäll C, Kull I, Scholtens S, Marike Boezen H,Koppelman GH, Wijga AH, Marenholz I, Esparza-Gordillo J, Lau S, Lee YA, Standl M,Tiesler CM, Flexeder C, Heinrich J, Myers RA, Ober C, Nicolae DL, Farrall M,Kumar A, Moffatt MF, Cookson WO, Lasky-Su J.  Genome-wide association study of body mass index in 23 000 individuals with and without asthma.  Clin Exp Allergy. 2013 Apr;43(4):463-74. doi: 10.1111/cea.12054. PubMed PMID: 23517042.

2351 Menke A, Klengel T, Rubel J, Brückl T, Pfister H, Lucae S, Uhr M, Holsboer F, Binder EB.  Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression.  Genes Brain Behav. 2013 Apr;12(3):289-96.

2350 Merkl C, Saalfrank A, Riesen N, Kühn R, Pertek A, Eser S, Hardt MS, Kind A, Saur D, Wurst W, Iglesias A, Schnieke A.  Efficient generation of rat induced pluripotent stem cells using a non-viral inducible vector. PLoS One. 2013;8(1):e55170. doi: 10.1371/journal.pone.0055170. Epub 2013 Jan 31.

2349 Michel S, Busato F, Genuneit J, Pekkanen J, Dalphin JC, Riedler J, Mazaleyrat N, Weber J, Karvonen AM, Hirvonen MR, Braun-Fahrländer C, Lauener R, von MutiusE, Kabesch M, Tost J; PASTURE study group. Farm exposure and time trends in earlychildhood may influence DNA methylation in genes related to asthma and allergy. Allergy. 2013 Mar;68(3):355-64. doi: 10.1111/all.12097. Epub 2013 Jan 25. PubMed PMID: 23346934.

2348 Møller RS, Weber YG, Klitten LL, Trucks H, Muhle H, Kunz WS, Mefford HC, Franke A, Kautza M, Wolf P, Dennig D, Schreiber S, Rückert IM, Wichmann HE, Ernst JP, Schurmann C, Grabe HJ, Tommerup N, Stephani U, Lerche H, Hjalgrim H, Helbig I, Sander T; EPICURE Consortium.  Exon-disrupting deletions of NRXN1 in idiopathic generalized epilepsy.Epilepsia.  Epilepsia. 2013;54:256-64.

2347 Mueller JC, Korsten P, Hermannstaedter C, Feulner T, Dingemanse NJ, Matthysen E, van Oers K, van Overveld T, Patrick SC, Quinn JL, Riemenschneider M, Tinbergen JM, Kempenaers B.  Haplotype structure, adaptive history and associations with exploratory behaviour of the DRD4 gene region in four great tit (Parus major) populations.  Mol Ecol. 2013;22(10):2797-809. [Epub 2013].

2346 Mühleisen TW, Mattheisen M, Strohmaier J, Degenhardt F, Priebe L, Schultz CC, Breuer R, Meier S, Hoffmann P; GROUP Investigators, Rivandeneira F, Hofman A, Uitterlinden AG, Moebus S, Gieger C, Emeny R, Ladwig KH, Wichmann HE, Schwarz M, Kammerer-Ciernioch J, Schlösser RG, Nenadic I, Sauer H, Mössner R, Maier W, Rujescu D, Lange C, Ophoff RA, Schulze TG, Rietschel M, Nöthen MM, Cichon S.  Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder.  Schizophr Res. 2012 Jun;138(1):69-73. doi: 10.1016/j.schres.2012.03.007.

2345 Müller SK, Bender A, Laub C, Högen T, Schlaudraff F, Liss B, Klopstock T, Elstner M.  Lewy body pathology is associated with mitochondrial DNA damage in Parkinson's disease.  Neurobiol Aging. 2013 Apr 6. pii: S0197-4580(13)00116-4. doi: 10.1016/j.neurobiolaging.2013.03.016.

2344  Müller-Rischart AK, Pilsl A, Beaudette P, Patra M, Hadian K, Funke M, Peis R, Deinlein A, Schweimer C, Kuhn PH, Lichtenthaler SF, Motori E, Hrelia S, Wurst W, Trümbach D, Langer T, Krappmann D, Dittmar G, Tatzelt J, Winklhofer KF.  The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO.  Mol Cell. 2013 Mar 7;49(5):908-21.

2343  Munding JB, Adai AT, Maghnouj A, Urbanik A, Zollner H, Liffers ST, Chromik AM, Uhl W, Szafranska-Schwarzbach A, Tannapfel A, Hahn SA.  Global microRNA expression profiling of microdissected tissues identifies miR-135b as a novel biomarker for pancreatic ductal adenocarcinoma.  Int J Cancer. 2012 Jul 15;131(2):E86-95. doi: 10.1002/ijc.26466. Epub 2011 Nov 19.

2342  Nakata S, Campos B, Bageritz J, Bermejo JL, Becker N, Engel F, Acker T, Momma S, Herold-Mende C, Lichter P, Radlwimmer B, Goidts V. LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells.  Brain Pathol. 2013 Jan;23(1):60-72.

2341 Nordström V, Monja Willershäuser M, Herzer S, Rozman J, von Bohlen und Halbach O, Sascha Meldner S, Rothermel U, Kaden S, Roth F, Waldeck C, Gretz N, Hrabé de Angelis M, Draguhn A, Klingenspor M, Gröne HJ, Jennemann R.  Neuronal expression of glucosylceramide synthase in centralnervous system regulates body weight and energy homeostasis.  PLoS Biol 11(3): e1001506. doi:10.1371/journal.pbio.1001506.

2340 Oates EC, Rossor AM, Hafezparast M, Gonzalez M, Speziani F, Macarthur DG, Lek M, Cottenie E, Scoto M, Foley AR, Hurles M, Houlden H, Greensmith L, Auer-Grumbach M, Pieber TR, Strom TM, Schule R, Herrmann DN, Sowden JE, Acsadi G, Menezes MP, Clarke NF, Züchner S; UK10K, Muntoni F, North KN, Reilly MM. Mutations in BICD2 Cause Dominant Congenital Spinal Muscular Atrophy and Hereditary Spastic Paraplegia. Am J Hum Genet. 2013 May 9. doi:pii: S0002-9297(13)00179-1.

2339 Otte DM, Barcena de Arellano ML, Bilkei-Gorzo A, Albayram O, Imbeault S, Jeung H, Alferink J, Zimmer A. Effects of chronic D-serine elevation on animal models of depression and anxiety-related behavior PLoS One. 2013 Jun 21;8(6):e67131. Print 2013.

2338 Over, B., S. Wetzel, C. Grütter, Y. Nakai, S. Renner, D. Rauh, H. Waldmann. Natural product derived fragments for fragment-based ligand discovery. Nat Chemistry, 2013, 5(1):21-8.

2337 Pandey RC, Michel S, Schieck M, Binia A, Liang L, Klopp N, Franke A, von Berg A, Bufe A, Rietschel E, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J,Illig T, Kabesch M.  Polymorphisms in extracellular signal-regulated kinase familyinfluence genetic susceptibility to asthma.  J Allergy Clin Immunol. 2013 Feb 2.doi:pii: S0091-6749(12)02676-0. 10.1016/j.jaci.2012.12.675. [Epub ahead of print]PubMed PMID: 23384682.

2336 Pandey RC, Michel S, Tesse R, Binia A, Schedel M, Liang L, Klopp N, Franke A, von Berg A, Bufe A, Rietschel E, Heinzmann A, Laub O, Simma B, Frischer T,Genuneit J, Illig T, Kabesch M.  Genetic variation in the Toll-like receptorsignaling pathway is associated with childhood asthma.  J Allergy Clin Immunol.2013 Feb;131(2):602-5. doi: 10.1016/j.jaci.2012.10.061. Epub 2012 Dec 28. PubMed PMID: 23273951.

2335 Papenfort K, Sun Y, Miyakoshi M, Vanderpool CK, Vogel J. Small RNA-mediated activation of sugar phosphatase mRNA regulates glucose homeostasis Cell 153:426-37

2334 Parzefall T, Shivatzki S, Lenz DR, Rathkolb B, Ushakov K, Karfunkel D, Shapira Y, Wolf M, Mohr M, Wolf E, Sabrautzki S, de Angelis MH, Frydman M, Brownstein Z, Avraham KB. (2013)  Cytoplasmic Mislocalization of POU3F4 Due to Novel Mutations Leads to Deafness in Humans and Mice.  Hum Mutat. doi: 10.1002/humu.22339. [Epub ahead of print].

2333 Paulus FM, Bedenbender J, Krach S, Pyka M, Krug A, Sommer J, Mette M, Nöthen MM, Witt SH, Rietschel M, Kircher T, Jansen A.  Association of rs1006737 in CACNA1C with alterations in prefrontal activation and fronto-hippocampal connectivity.  Hum Brain Mapp. 2013 Feb 13. doi: 10.1002/hbm.22244. [Epub ahead of print].

2332 Pechlivanis S, Mühleisen TW, Möhlenkamp S, Schadendorf D, Erbel R, Jöckel KH, Hoffmann P, Nöthen MM, Scherag A, Moebus S;Heinz Nixdorf Recall Study Investigative Group. Risk loci for coronary artery calcification replicated at 9p21 and 6q24 in the Heinz Nixdorf Recall Study.  BMC Med Genet. 2013 Feb 8;14:23.

2331  Peitz, M., Jungverdorben, J., Brüstle, O. (2013) Disease-specific iPS cell models in neuroscience. Curr Mol Med (in press).

2330 Pernhorst K, Herms S, Hoffmann P, Cichon S, Schulz H, Sander T, Schoch S, Becker AJ, Grote A.  TLR4, ATF-3 and IL8 inflammation mediator expression correlates with seizure frequency in human epileptic brain tissue.  Seizure. 2013 May 22. doi:pii: S1059-1311(13)00144-1. 10.1016/j.seizure.2013.04.023. [Epub ahead of print].

2329 Pernhorst K, van Loo KM, von Lehe M, Priebe L, Cichon S, Herms S, Hoffmann P, Helmstaedter C, Sander T, Schoch S, Becker AJ.  Rs6295 promoter variants of the serotonin type 1A receptor are differentially activated by c-Jun in vitro and correlate to transcript levels in human epileptic brain tissue.  Brain Res. 2013 Mar 7;1499:136-44. doi: 10.1016/j.brainres.2012.12.045. Epub 2013 Jan 16.PMID: 23333373.

2328  Petrakis S, Schaefer MH, Wanker EE, Andrade-Navarro MA Aggregation of polyQ-extended proteins is promoted by interaction with their natural coiled-coil partners.  BioEssays 35 (6): 503-507.

2327  Potaczek DP, Michel S, Sharma V, Zeilinger S, Vogelberg C, von Berg A, Bufe A,Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T, Genuneit J, Illig T,Kabesch M.  Different FCER1A polymorphisms influence IgE levels in asthmatics and  non-asthmatics.  Pediatr Allergy Immunol. 2013 Jun 3. PMID: 23725541.

2326 Pott W, Albayrak O, Hinney A, Hebebrand J, Pauli-Pott U.  Successful treatment with atomoxetine of an adolescent boy with attention deficit/hyperactivity disorder, extreme obesity, and reduced melanocortin 4 receptor function.  Obes Facts. 2013;6(1):109-15. doi: 10.1159/000348792. Epub 2013 Mar 6. PubMed PMID:23493066.

2325  Prinz A, Selesnew L, Liss B, Roeper J, Carlsson T.  Increased excitability of serotonin neurons in the dorsal raphe nucleus in the 6-OHDA mouse model of Parkinson's disease.  Experimental Neurology (Submitted).

2324 Puk O, Hrabe de Angelis M, Graw J.  Longitudinal fundus and retinal studies with SD-OCT - a comparison of five mouse inbred strains.  Mamm Genome 2013, [Epub ahead of print]. doi 10.1007/s00335-013-9457-z.

2323 Puk O, Yan X, Sabrautzki S, Fuchs H, Gailus-Durner V, Hrab? de Angelis M, Graw J.  Novel small-eye allele in paired box gene 6 (Pax6) is caused by a pointmutation in intron 7 and creates a new exon.  Mol Vis. 2013 Apr 12;19:877-84.Print 2013. PubMed PMID: 23592925; PubMed Central PMCID: PMC3626302.

2322 Rakovic A, Shurkewitsch K, Seibler P, Grünewald A, Zanon A, Hagenah J, Krainc D, Klein C.  PTEN-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem (iPS) cell-derived neurons. J Biol Chem 2013;25;288:2223-2237.

2321 Ramm Sander P, Hau P, Koch S, Schütze K, Bogdahn U, Kalbitzer HR, Aigner L.  Stem cell metabolic and spectroscopic profiling.  Trends Biotechnol. 2013Mar;31(3):204-13. doi: 10.1016/j.tibtech.2013.01.008. Epub 2013 Feb 4. PubMed PMID: 23384506.

2320  Rauh, D. Chemical Biology ? current and next challenges. ACS Chem Biol, 2013, 8(1):1-2.

2319  Reinhardt P, Schmid B, Burbulla LF, Schöndorf DC, Wagner L, Glatza M, Höing S, Hargus G, Heck SA, Dhingra A, Wu G, Müller S, Brockmann K, Kluba T Maisel M, Krüger R, Berg D, Tsytsyura Y, Thiel CS, Psathaki K, Drexler H, Klingauf J, Kuhlmann T, Klewin M, Müller H, Gasser T, Schöler H, Sterneckert J.  Gene-correction in iPSCs uncovers multiple pathogenic changes associated with LRRK2 G2019S. Cell Stem Cell. 2013 Mar 7;12(3):354-67. doi: 10.1016/j.stem.2013.01.008.

2318 Reuss DE, Piro RM, Jones DT, Simon M, Ketter R, Kool M, Becker A, Sahm F,Pusch S, Meyer J, Hagenlocher C, Schweizer L, Capper D, Kickingereder P, Mucha J, Koelsche C, Jäger N, Santarius T, Tarpey PS, Stephens PJ, Andrew Futreal P, Wellenreuther R, Kraus J, Lenartz D, Herold-Mende C, Hartmann C, Mawrin C, Giese N, Eils R, Collins VP, König R, Wiestler OD, Pfister SM, von Deimling A.  Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations.  Acta Neuropathol. 2013 Mar;125(3):351-8.

2317 Ried JS, Baurecht H, Stückler F, Krumsiek J, Gieger C, Heinrich J, Kabesch M, Prehn C, Peters A, Rodriguez E, Schulz H, Strauch K, Suhre K, Wang-Sattler R, Wichmann HE, Theis FJ, Illig T, Adamski J, Weidinger S.  Integrative genetic and metabolite profiling analysis suggests altered phosphatidylcholine metabolism in asthma.   Allergy. 2013 Mar 1. doi: 10.1111/all.12110.

2316 Rietschel M, Treutlein J. The genetics of alcohol dependence.  Ann N Y Acad Sci. 2013 Apr;1282(1):39-70. doi: 10.1111/j.1749-6632.2012.06794.

2315 Roewer L, Nothnagel M, Gusmão L, Gomes V, González M, Corach D, Sala A, Alechine E, Palha T, Santos N, Ribeiro-Dos-Santos A, Geppert M, Willuweit S, Nagy M, Zweynert S, Baeta M, Núñez C, Martínez-Jarreta B, González-Andrade F, Fagundes de Carvalho E, da Silva DA, Builes JJ, Turbón D, Lopez Parra AM, Arroyo-Pardo E, Toscanini U, Borjas L, Barletta C, Ewart E, Santos S, Krawczak M (2013).  Continent-wide decoupling of y-chromosomal genetic variation from language and geography in native South americans.  PLoS Genet 9(4):e1003460.

2314 Rücker FG, Russ AC, Cocciardi S, Kett H, Schlenk RF, Botzenhardt U, Langer C, Krauter J, Fröhling S, Schlegelberger B, Ganser A, Lichter P, Zenz T, Döhner H, Döhner K, Bullinger L.  Altered miRNA and gene expression in acute myeloid leukemia with complex karyotype identify networks of prognostic relevance.  Leukemia. 2013;27:353-61.

2313 Russell CD, Haas J.  Cyclosporine has a potential role in the treatment of SARS.  J Infect. 2013 Feb 6.

2312  Sabrautzki S, Janas E, Lorenz-Depiereux B, Calzada-Wack J, Aguilar-Pimentel JA, Rathkolb B, Diener S, Adler T, Busch DH, Fuchs H, Gailus-Durner V, Wolfe E, Ollert M, Strom TM, Höfler H, Neff F, Hrabe de Angelis M.? An ENU mutagenesis derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease? Am J Pathol. 2013 Jun 18. pii: S0002-9440(13)00349-0. doi: 10.1016/j.ajpath.2013.04.027. [Epub ahead of print].

2311 Sarek G, Ma L, Enbäck J, Järviluoma A, Moreau P, Haas J, Gessain A, Koskinen PJ, Laakkonen P, Ojala PM.  Kaposi's sarcoma herpesvirus lytic replication compromises apoptotic response to p53 reactivation in virus-induced lymphomas.  Oncogene. 2013 Feb 28;32(9):1091-8.

2310 Schaefer AS, Bochenek G, Manke T, Nothnagel M, Graetz C, Thien A, Jockel-Schneider Y, Harks I, Staufenbiel I, Wijmenga C, Eberhard J, Guzeldemir-Akcakanat E, Cine N, Folwaczny M, Noack B, Meyle J, Eickholz P, Trombelli L, Scapoli C, Nohutcu R, Bruckmann C, Doerfer C, Jepsen S, Loos BG, Schreiber S (2013).  Validation of reported genetic risk factors for periodontitis in a large-scale replication study.  J Clin Periodontol 40(6):563-72.

2309 Scheffler M, Zander T, Nogova L, Kobe C, Kahraman D, Dietlein M, Papachristou I, Heukamp L, Büttner R, Boellaard R, Lammertsma AA, Querings S, Stoelben E, Engel-Riedel W, Neumaier B, Wolf J:  Prognostic impact of [18f]fluorothymidine and [18f]fluoro-d-glucose baseline uptakes in patients with lung cancer treated first-line with erlotinib.  PLoS One 2013;8:e53081.

2308 Schelhorn SE, Fischer M, Tolosi L, Altmüller J, Nürnberg P, Pfister H, Lengauer T, Berthold F. Sensitive detection of viral transcripts in human tumor transcriptomes. PLoS Comput Biol, in press.

2307 Scherag  A.  Missing heritability of complex traits and G-E interactions. GMS Medizinische Informatik, Biometrie und Epidemiologie 2013, Vol. 9(2), ISSN 1860-9171.

2306  Schimmelmann BG, Hinney A, Scherag A, Pütter C, Pechlivanis S, Cichon S, Jöckel KH, Schreiber S, Wichmann HE, Albayrak O, Dauvermann M, Konrad K, Wilhelm C, Herpertz-Dahlmann B, Lehmkuhl G, Sinzig J, Renner TJ, Romanos M, Warnke A, Lesch KP, Reif A, Hebebrand J. Bipolar disorder risk alleles in children with ADHD.  J Neural Transm. 2013 May 28. [Epub ahead of print] PubMed PMID: 23712748.

2305  Schirwitz, C., Löffler, F., Felgenhauer, T., Stadler, V., Nesterov-Mueller, A., Dahint, R., Breitling, F. & Bischoff, F.R. Purification of high-complexity peptide microarrays by spatially resolved array transfer to gold-coated membranes.  Adv Materials 25, 1598-1602.

2304 Schmitt J, Apfelbacher C, Heinrich J, Weidinger S, Romanos M.  Association of atopic eczema and attention-deficit/hyperactivity disorder - meta-analysis of epidemiologic studies.  Z Kinder Jugendpsychiatr Psychother 2013; 41:35-44.

2303 Schneider R., A. Gohla, J.R. Simard, D.B. Yadav, Z. Fang, W.A.L. van Otterlo, D. Rauh. Overcoming compound fluorescence in the FLiK screening assay with red-shifted fluorophores. J Am Chem Soc, 2013, in press.

2302 Schneider R., C. Beumer, J.R. Simard, C. Grütter, D. Rauh. Selective Detection of Allosteric Phosphatase Inhibitors. J Am Chem Soc, 2013, 135(18):6838-41.

2301 Scholz, B.A., Harth-Hertle, M.L., Malterer, G. Haas, J., Ellwart, J., Schulz, T.F., Kempkes, B.  Abortive lytic reactivation of KSHV in CBF1 deficient human B cell lines.  PLOS Pathogens. in press.

2300 Schoofs T, Rohde C, Hebestreit K, Klein HU, Göllner S, Schulze I, Lerdrup M, Dietrich N, Agrawal-Singh S, Witten A, Stoll M, Lengfelder E, Hofmann WK, Schlenke P, Büchner T, Hansen K, Berdel WE, Rosenbauer F, Dugas M, Müller-Tidow C. DNA methylation changes are a late event in acute promyelocytic leukemia and coincide with loss of transcription factor binding.  Blood. 2013 Jan 3;121(1):178-87.

2299  Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium, Schork NJ, Andreassen OA, Dale AM; Collaborators: Absher D, Agudo A, Almgren P, Ardissino D, Assimes TL, Bandinelli S, Barzan L, Bencko V, Benhamou S, Benjamin EJ, Bernardinelli L, Bis J, Boehnke M, Boerwinkle E, Boomsma DI, Brennan P, Canova C, Castellsagué X, Chanock S, Chasman D, Conway DI, Dackor J, de Geus EJ, Duan J, Elosua R, Everett B, Fabianova E, Ferrucci L, Foretova L, Fortmann SP, Franceschini N, Frayling T, Furberg C, Gejman PV, Groop L, Gu F, Guralnik J, Hankinson SE, Haritunians T, Healy C, Hofman A, Holcátová I, Hunter DJ, Hwang SJ, Ioannidis JP, Iribarren C, Jackson AU, Janout V, Kaprio J, Kim Y, Kjaerheim K, Knowles JW, Kraft P, Ladenvall C, Lagiou P, Lanthrop M, Lerman C, Levinson DF, Levy D, Li MD, Lin DY, Lips EH, Lissowska J, Lowry R, Lucas G, Macfarlane TV, Maes H, Mannucci PM, Mates D, Mauri F, McGovern JA, McKay JD, McKnight B, Melander O, Merlini PA, Milaneschi Y, Mohlke KL, O'Donnell CJ, Pare G, Penninx BW, Perry J, Posthuma D, Preis SR, Psaty B, Quertermous T, Ramachandran VS, Richiardi L, Ridker P, Rose J, Rudnai P, Salomaa V, Sanders AR, Schwartz SM, Shi J, Smit JH, Stringham HM, Szeszenia-Dabrowska N, Tanaka T, Taylor K, Thacker E, Thornton L, Tiemeier H, Tuomilehto J, Uitterlinden AG, van Duijn CM, Vink JM, Vogelzangs N, Voight BF, Walter S, Willemsen G, Zaridze D, Znaor A, Absher D, Akil H, Anjorin A, Backlund L, Badner JA, Barchas JD, Barrett TB, Bass N, Bauer M, Bellivier F, Bergen SE, Berrettini W, Blackwood D, Bloss CS, Boehnke M, Breen G, Breuer R, Bunner WE, Burmeister M, Byerley W, Caesar S, Chambert K, Cichon S, St Clair D, Collier DA, Corvin A, Coryell WH, Craddock N, Craig DW, Daly M, Day R, Degenhardt F, Djurovic S, Dudbridge F, Edenberg HJ, Elkin A, Etain B, Farmer AE, Ferreira MA, Ferrier I, Flickinger M, Foroud T, Frank J, Fraser C, Frisén L, Gershon ES, Gill M, Gordon-Smith K, Green EK, Greenwood TA, Grozeva D, Guan W, Gurling H, Gustafsson Ó, Hamshere ML, Hautzinger M, Herms S, Hipolito M, Holmans PA, Hultman CM, Jamain S, Jones EG, Jones I, Jones L, Kandaswamy R, Kennedy JL, Kirov GK, Koller DL, Kwan P, Landén M, Langstrom N, Lathrop M, Lawrence J, Lawson WB, Leboyer M, Lee PH, Li J, Lichtenstein P, Lin D, Liu C, Lohoff FW, Lucae S, Mahon PB, Maier W, Martin NG, Mattheisen M, Matthews K, Mattingsdal M, McGhee KA, McGuffin P, McInnis MG, McIntosh A, McKinney R, McLean AW, McMahon FJ, McQuillin A, Meier S, Melle I, Meng F, Mitchell PB, Montgomery GW, Moran J, Morken G, Morris DW, Moskvina V, Muglia P, Mühleisen TW, Muir WJ, Müller-Myhsok B, Myers RM, Nievergelt CM, Nikolov I, Nimgaonkar V, Nöthen MM, Nurnberger JI, Nwulia EA, O'Dushlaine C, Osby U, Óskarsson H, Owen MJ, Petursson H, Pickard BS, Porgeirsson P, Potash JB, Propping P, Purcell SM, Quinn E, Raychaudhuri S, Rice J, Rietschel M, Ruderfer D, Schalling M, Schatzberg AF, Scheftner WA, Schofield PR, Schulze TG, Schumacher J, Schwarz MM, Scolnick E, Scott LJ, Shilling PD, Sigurdsson E, Sklar P, Smith EN, Stefansson H, Stefansson K, Steffens M, Steinberg S, Strauss J, Strohmaier J, Szelinger S, Thompson RC, Tozzi F, Treutlein J, Vincent JB, Watson SJ, Wienker TF, Williamson R, Witt SH, Wright A, Xu W, Young AH, Zandi PP, Zhang P, Zöllner S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bitter I, Black DW, Børglum AD, Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger C, Cormican P, Danoy PA, Datta S, DeHert M, Demontis D, Dikeos D, Donnelly P, Donohoe G, Duan J, Duong L, Dwyer S, Fanous A, Fink-Jensen A, Freedman R, Freimer NB, Friedl M, Gejman PV, Georgieva L, Giegling I, Glenthøj B, Godard S, Golimbet V, de Haan L, Hansen M, Hansen T, Hartmann AM, Henskens FA, Hougaard DM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jönsson EG, Jürgens G, Kahn RS, Keller MC, Kendler KS, Kenis G, Kenny E, Kim Y, Konnerth H, Konte B, Krabbendam L, Krasucki R, Lasseter VK, Laurent C, Lencz T, Lerer F, Levinson DF, Liang KY, Lieberman JA, Linszen DH, Lönnqvist J, Loughland CM, Maclean AW, Maher BS, Malhotra AK, Mallet J, Malloy P, McGrath JJ, McLean DE, Michie PT, Milanova V, Mors O, Mortensen PB, Mowry BJ, Myin-Germeys I, Neale B, Nertney DA, Nestadt G, Nielsen J, Nordentoft M, Norton N, O'Neill F, Olincy A, Olsen L, Ophoff RA, Ørntoft TF, van Os J, Pantelis C, Papadimitriou G, Pato CN, Pato MT, Peltonen L, Pickard B, Pietiläinen OP, Pimm J, Posthuma D, Pulver AE, Puri V, Quested D, Rasmussen HB, Réthelyi JM, Ribble R, Riley BP, Rossin L, Ruggeri M, Rujescu D, Sanders AR, Schall U, Schwab SG, Scolnick E, Scott RJ, Shi J, Silverman JM, Spencer CC, Strange A, Strengman E, Stroup T, Suvisaari J, Terenius L, Thirumalai S, Timm S, Toncheva D, Tosato S, van den Oord EJ, Veldink J, Visscher PM, Walsh D, Wang AG, Werge T, Wiersma D, Wildenauer DB, Williams HJ, Williams NM, van Winkel R, Wormley B, Zammit S.  All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.  PLoS Genet. 2013 Apr;9(4):e1003449.

2298  Schüle R, Dictus C, Campos B, Wan F, Felsberg J, Ahmadi R, Centner FS, Grabe N, Reifenberger G, Bermejo JL, Unterberg A, Herold-Mende C. Potential canonical wnt pathway activation in high-grade astrocytomas. Scientific World Journal. 2012;2012:697313. doi: 10.1100/2012/697313. Epub 2012 Aug 2.

2297  Schulte JH, Lindner S, Bohrer A, Maurer J, De Preter K, Lefever S, Heukamp L, Schulte S, Molenaar J, Versteeg R, Thor T, Künkele A, Vandesompele J, Speleman F, Schorle H, Eggert A, Schramm A. MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells. Oncogene, doi: 10.1038/onc.2012.106.

2296 Schulte LN, Westermann AJ, Vogel J  Differential activation and functional specialisation of miR-146 and miR-155 in innate immune sensing  Nucleic Acids Research 41(1):542-53

2295 Schultheis A, Wolf J, Büttner R. Lung cancer. Molecular pathology and personalized therapy. Internist (Berl) 2013;54:179-180, 182-177..

2294 Serpi R, Klein-Rodewald T, Calzada-Wack J, Neff F, Schuster T, Gailus-Durner V, Fuchs H, Poutanen M, Hrabé de Angelis M, Esposito I:  Inbred wild type mouse strains have distinct spontaneous morphological phenotypes.  Histol Histopathol. 2013 Jan;28(1):79-88.

2293 Shariati, S. A. M., Lau, P., Hassan, B. A., Mu?ller, U.C., Dotti, C. G., Strooper, B.,  and Annette Gärtner, A.  APLP2 regulates neuronal stem cell differentiation during cortical development.  J Cell Sci. 2013 Mar 1;126(Pt 5):1268-77. doi: 10.1242/jcs.122440. Epub 2013 Jan 23

2292 Sharma M, Krüger R, Gasser T.  From Genome-wide association studies to next generation sequencing: Lessons from the past and planning for the future.  JAMA Neurol (in press)

2291 Siegert S, Hampe J, Schafmayer C, von Schönfels W, Egberts JH, Försti A, Chen B, Lascorz J, Hemminki K, Franke A, Nothnagel M, Nöthlings U, Krawczak M.  Genome-wide investigation of gene-environment interactions in colorectal cancer.  Hum Genet. 2013 Feb;132(2):219-31.

2290 Sigl M, Spoerl S, Schnittger S, Meissner J, Rummelt C, Peschel C, Duyster J, Ho AD, von Bubnoff N. Imatinib failure and response to dasatinib in a patient with chronic myeloid leukemia in blast crisis and a novel, nine-nucleotide BCR-ABL insertion mutation.  Blood Cancer J. 2013 Mar 8;3:e104. doi: 10.1038/bcj.2013.3.

2289 Starokadomskyy P, Nathan Gluck, Haiying Li, Baozhi Chen, Mathew Wallis, Gabriel N Maine, Xicheng Mao, Iram Zaidi, Marco Y Hein, Fiona McDonald, Steffen Lenzner, Agnes Zecha, Hans-Hilger Ropers, Andreas W Kuss, Julie McGaughran, Jozef Gécz, Ezra Burstein.  CCDC22 deficiency in humans blunts activation of pro-inflammatory NF-kB signaling. Accepted at the Journal of Clinical Investigation. J Clin Invest. 2013 May 1;123(5):2244-56. doi: 10.1172/JCI66466. Epub 2013 Apr 8.

2288 Stogmann E, Reinthaler E, Eltawil S, El Etribi MA, Hemeda M, El Nahhas N, Gaber AM, Fouad A, Edris S, Benet-Pages A, Eck SH, Pataraia E, Mei D, Brice A, Lesage S, Guerrini R, Zimprich F, Strom TM, Zimprich A. Autosomal recessive cortical myoclonic tremor and epilepsy: association with a mutation in the potassium channel associated gene CNTN2. Brain. 2013 Apr;136(Pt 4):1155-60

2287 Stölting G, Teodorescu G, Begemann B, Schubert J, Nabbout R, Toliat MR, Sander T, Nürnberg P, Lerche H, Fahlke C.  Regulation of ClC-2 gating by intracellular ATP.  Pflugers Arch. 2013 May 1. [Epub ahead of print].

2286 Suter B, Fontaine JF, Yildirimman R, Rasko T, Schaefer MH, Rasche A, Porras P, Vazquez-Alvarez BM, Russ J, Rau K, Foulle R, Zenkner M, Saar K, Herwig R, Andrade-Navarro MA, Wanker EE.

2285 Tahoun, A., Mahajan, S., Paxton, E., Malterer, G., Donaldson, D., O?Shea, M., Roe, A.J., Shaw, D.J., Gally, D.L., Lengeling, A., Mabbott, N., Haas, J. and Mahajan, A. Salmonella transform follicle-associated epithelial cells into antigen sampling M cells to promote their intestinal invasion.  Cell Host & Microbe 12(5):645-5669.

2284 Terwisscha van Scheltinga AF, Bakker SC, van Haren NE, Derks EM,Buizer-Voskamp JE, Boos HB, Cahn W, Hulshoff Pol HE, Ripke S, Ophoff RA, Kahn RS; Psychiatric Genome-wide Association Study Consortium; Collaborators: Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L, Visscher PM, Posthuma D, Ruderfer DM, Fanous A, Stefansson H, Steinberg S, Mowry BJ, Golimbet V, De Hert M, Jonsson EG, Bitter I, Pietiläinen OP, Collier DA, Tosato S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bergen SE, Black DW, Børglum AD, Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger C, Cormican P, Craddock N, Danoy PA, Datta S, de Haan L, Demontis D, Dikeos D, Djurovic S, Donnelly P, Donohoe G, Duong L, Dwyer S, Fink-Jensen A, Freedman R, Freimer NB, Friedl M, Georgieva L, Giegline I, Gill M, Glenthøj B, Godard S, Hamshere M, Hansen M, Hansen T, Hartmann AM, Henskens FA, Hougaard DM, Hultman CM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jürgens G, Kahn RS, Keller MC, Kenis G, Kenny E, Kim Y, Kirov GK, Konnerth H, Konte B, Krabbendam L, Krasucki R, Lasseter VK, Laurent C, Lawrence J, Lencz T, Lerer F, Liang KY, Lichtenstein P, Lieberman JA, Linszen DH, Lönnqvist J, Loughland CM, Maclean AW, Maher BS, Maier W, Mallet J, Malloy P, Mattheisen M, Mattingsdal M, McGhee KA, McGrath JJ, McIntosh A, McLean DE, McQuillin A, Melle I, Michie PT, Milanova V, Morris DW, Mors O, Mortensen PB, Moskvina V, Muglia P, Myin-Germeys I, Nertney DA, Nestadt G, Nielsen J, Nikolov I, Nordentoft M, Norton N, Nöthen MM, O'Dushlaine C, Olincy A, Olsen L, O'Neill F, Ørntoft TF, Owen MJ, Pantelis C, Papadimitriou G, Pato MT, Peltonen L, Petursson H, Pickard B, Pimm J, Pulver AE, Puri V, Quested D, Quinn EM, Rasmussen HB, Réthelyi JM, Ribble R, Rietschel M, Riley BP, Ruggeri M, Schall U, Schulze TG, Schwab SG, Scott RJ, Shi J, Sigurdsson E, Silverman JM, Spencer CC, Stefansson K, Strange A, Strengman E, Stroup TS, Suvisaari J, Terenius L, Thirumalai S, Thygesen JH, Timm S, Toncheva D, van den Oord E, van Os J, van Winkel R, Veldink J, Walsh D, Wang AG, Wiersma D, Wildenauer DB, Williams HJ, Williams NM, Wormley B, Zammit S, Sullivan PF, O'Donovan MC, Daly MJ, Gejman PV.   Genetic schizophrenia risk variants jointly modulate total brain and white matter volume.  Biol Psychiatry. 2013 Mar 15;73(6):525-31.

2283 Tews D, Fischer-Posovszky P, Fromme T, Klingenspor M, Fischer J, Rüther U, Barth TF, Möller P, Debatin KM, Wabitsch M.  FTO deficiency induces UCP-1 expression and mitochondrial uncoupling in adipocytes'  Endocrinology. 2013 Jun 10. [Epub ahead of print]

2282 Thiele F, Cohrs CM, Przemeck GK, Wurst W, Fuchs H, Hrabé de Angelis M.   In vitro analysis of bone phenotypes in Col1a1 and Jagged1 mutant mice using a standardized osteoblast cell culture system. J Bone Miner Metab. 2013 Jan 31 PMID: 23371561.

2281 Tolosi, L., et al. A method for finding consensus breakpoints in the cancer genome from copy number data. Bioinformatics. 2013 Jun 19. [Epub ahead of print].

2280 Tönjes M, Barbus S, Park YJ, Wang W, Schlotter M, Lindroth AM, Pleier SV, Bai AHC, Karra D, Piro RM, Felsberg J, Addington A, Lemke D, Weibrecht I, Hovestadt V, Rolli CG, Campos B, Turcan S, Sturm D, Witt H, Chan TA, Herold-Mende C, Kemkemer R, König R, Schmidt K, Hull WE, Pfister SM, Jugold M, Hutson SM, Plass C, Okun JG, Reifenberger G, Lichter P, Radlwimmer B.  BCAT1 promotes cell proliferation via amino acid catabolism in IDH1 wildtype gliomas.  Nat Med. 2013 Jun 23. doi: 10.1038/nm.3217. [Epub ahead of print]

2279 Tozzi F, Teumer A, Munafò M, Rawal R, Kazeem G, Gerbaulet M, McArdle W, Chilcoat H, Döring A, Dahmen N, Mooser V, Nauck M, Ring SM, Rubio JP, Vollenweider P, Waeber G, John U, Völzke H, Homuth G, Freyberger HJ, Völker U, Davey-Smith G, Gieger C, Preisig M, Grabe HJ.  A genomewide association study of smoking relapse in four European population-based samples.  Psychiatr Genet. 2013 Mar 27. Pubmed PMID: 23542338

2278 Tran Mau-Them F, Willems M, Albrecht B, Sanchez E, Puechberty J, Endele S, Schneider A, Ruiz Pallares n, Missirian C, Rivier F, Girard M, Holder M, Manouvrier S, Touitou I, Lefort G, Sarda P, Moncla A, Drunat S, Wieczorek D, Genevieve D.  Expanding the phentoype of IQSEC2 mutations: truncating mutations in severe intellectual disability.  Eur J Hum Genet 2013; doi: 10.1038/ejhg.2013.113.

2277 Urich R., G. Wishart, M. Kiczun, A. Richters, N. Tidten-Luksch, D. Rauh, B. Sherborne, P.G. Wyatt and R. Brenk. De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments. ACS Chem Biol, 2013, in press.

2276 Van Bebber F, Hruscha A, Willem M, Schmid B, Haass C. Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes. Journal of Neurochemistry (manuscript in press).

2275 Van Eijk J, Demirakca T, Frischknecht U, Hermann D, Mann K, Ende G.   Rapid partial regeneration of brain volume during the first 14 days of abstinence from alcohol  Alcohol Clin Exp Res. 2013 Jan;37(1):67-74. doi: 10.1111/j.1530-0277.2012.01853.x. Epub 2012 Oct 16.

2274 Vengeliene V, Noori H, Spanagel R.  The use of a novel Drinkometer system for assessing pharmacological treatment effects on alcohol consumption in rats.  Alcohol Clin Exp Res. 2013 Jan;37 Suppl 1:E322-8.

2273 Venit T, Dzijak R, Kalendová A, Kahle M, Roho?ková J, Schmidt V, Rülicke T, Rathkolb B, Hans W, Bohla A, Eickelberg O, Stoeger T, Wolf E, Yildirim AÖ, Gailus-Durner V, Fuchs H, de Angelis MH, Hozák P. (2013)  Mouse nuclear Myosin I knock-out shows interchangeability and redundancy of Myosin isoforms in the cell nucleus.  PLoS One. 8(4):e61406. doi: 10.1371/journal.pone.0061406.

2272 Verdugo RA, Zeller T, Rotival M, Wild PS, Münzel T, Lackner KJ, Weidmann H, Ninio E, Trégouët DA, Cambien F, Blankenberg S, Tiret L.  Graphical modeling of gene expression in monocytes suggests molecular mechanisms explaining increased atherosclerosis in smokers. PLoS One. 2013;8(1):e50888

2271 Vidy A, T. Sacher, H. Adler, S. Jordan, U. H. Koszinowski and Z. Ruzsics Systemic and local infection routes govern different cellular dissemination pathways during gamma-herpesvirus infection in vivo.  J Virol, 87 (2013): 4596-4608.

2270 Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, Cooper JD, Dastani Z, Li R, Houston DK, Wood AR, Michaëlsson K, Vandenput L, Zgaga L, Yerges-Armstrong LM, McCarthy MI, Dupuis J, Kaakinen M, Kleber ME, Jameson K, Arden N, Raitakari O, Viikari J, Lohman KK, Ferrucci L, Melhus H, Ingelsson E, Byberg L, Lind L, Lorentzon M, Salomaa V, Campbell H, Dunlop M, Mitchell BD, Herzig KH, Pouta A, Hartikainen AL; Genetic Investigation of Anthropometric Traits-GIANT Consortium, Streeten EA, Theodoratou E, Jula A, Wareham NJ, Ohlsson C, Frayling TM, Kritchevsky SB, Spector TD, Richards JB, Lehtimäki T, Ouwehand WH, Kraft P, Cooper C, März W, Power C, Loos RJ, Wang TJ, Järvelin MR, Whittaker JC, Hingorani AD, Hyppönen E.  Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts.  PLoS Med. 2013;10(2):e1001383. doi: 10.1371/journal.pmed.1001383. Epub 2013 Feb 5.

2269 Vogel H, Mirhashemi F, Liehl B, Taugner F, Kluth O, Kluge R, Joost HG, Schürmann A.  Estrogen Deficiency Aggravates Insulin Resistance and Induces ?-Cell Loss and Diabetes in Female New Zealand Obese Mice.  Horm Metab Res. Jan 15 (2013).

2268 Vogel H, Montag D, Kanzleiter T, Jonas W, Matzke D, Scherneck S, Chadt A, Töle J, Kluge R, Joost HG, Schürmann A.  An interval of the obesity QTL Nob3.38 within a QTL hotspot on chromosome 1 modulates behavioral phenotypes.  PLoS One. 8:e53025 (2013).

2267 Volckmar AL, Pütter C, Song JY, Graniger J, Knoll N, Wolters B, Hebebrand J, Scherag A, Reinehr T, Hinney A. Analyses of Non-Synonymous Obesity Risk Alleles in SH2B1 (rs7498665) and APOB48R (rs180743) in Obese Children and Adolescents Undergoing a 1-year Lifestyle Intervention.  Exp Clin Endocrinol Diabetes. 2013 (in press)

2266 Wang X.D., Su Y.-A., Wagner K.V., Avrabos C., Scharf S.H., Hartmann J., Wolf M., Liebl C., Kuehne C., Wurst W., Holsboer F., Eder M., Deussing J.M., Mueller M.B., Schmidt M.V.  Nectin-3 Links CRHR1 Signaling to Stress-Induced Memory Deficits and Spine Loss.  Nat Neurosci. 2013 Jun;16(6):706-13. doi: 10.1038/nn.3395. Epub 2013 May 5.

2265 Ward A, Balwierz A, Zhang JD, Küblbeck M, Pawitan Y, Hielscher T, Wiemann S, Sahin O (2012)  Re-expression of microRNA-375 reverts both tamoxifen resistance and accompanied EMT-like properties in breast cancer.  Oncogene 2013, 32(9):1173-1182.

2264 Wefers B, Meyer M, Ortiz O, Hrabé de Angelis M, Hansen J, Wurst W, Kühn R.   Direct production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotides. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3782-7.

2263 Weidner C, Wowro SJ, Freiwald A, Kawamoto K, Witzke A, Kliem M, Siems K, Müller-Kuhrt L, Schroeder FC, Sauer S.  Amorfrutin B is an efficient natural peroxisome proliferator-activated receptor gamma (PPAR?) agonist with potent glucose-lowering properties.  Diabetologia. 2013 May 18. Epub ahead of print]

2262 Weimann M, Grossmann A, Woodsmith J, Ozkan Z, Birth P, Meierhofer D, Benlasfer N, Valovka T, Timmermann B, Wanker EE, Sauer S, Stelzl U.  A Y2H-seq approach defines the human protein methyltransferase interactome.  Nat Methods. 2013 10:  doi: 10.1038/nmeth.2397.

2261 Weiss D, Walach M, Meisner C, Fritz M, Scholten M, Breit S, Plewnia C, Bender B, Gharabaghi A, Wächter T, Krüger R.  Nigral stimulation for resistant axial motor impairment in Parkinson's disease? A randomized controlled trial.  Brain. 2013 Jul;136(Pt 7):2098-2108. Epub 2013 Jun 11.

2260 Wrzodek C, Büchel F, Dräger A, Ruff M, and Zell, A.  Precise generation of systems biology models from KEGG pathways.  BMC Systems Biology, 2013. doi:10.1186/1752-0509-7-15.

2259 Xie K, Liu Y, Hao W, Walter S, Penke B, Hartmann T, Schachner M, Fassbender K. Tenascin-C deficiency ameliorates Alzheimer's disease-related pathology in mice.  Neurobiol Aging. 2013 May 11.

2258 Yu X, Seitz S, Pointon T, Bowlin JL, Cohrs RJ, Jonji? S, Haas J, Wellish M, Gilden D.  Varicella zoster virus infection of highly pure terminally differentiated human neurons.  J Neurovirol. 2013 Feb;19(1):75-81..

2257 Zeisel A, Yitzhaky A, Koerner C, Lauriola M, Cohen-Dvashi H, Kostler WJ, Yarden Y, Wiemann S, Domany E:  qCMA: A Desktop Application for Quantitative Collective Cell Migration Analysis.  J Biomol Screen 2013, 18(3):356-360.

2256 Zhang L, Karsten P, Hamm S, Pogson JH, Lutz AK, Exner N, Haass C, Whitworth A, Winklhofer K, Schulz JB, Voigt A.  TRAP1 rescues PINK1 loss-of-function phenotypes.  Hum Mol Genet. 2013 Mar 21. [Epub ahead of print].

2012

2255 Asselbergs FW, Guo Y, van Iperen EP, Sivapalaratnam S, Tragante V, Lanktree MB, Lange LA, Almoguera B, Appelman YE, Barnard J, Baumert J, Beitelshees AL, Bhangale TR, Chen YD, Gaunt TR, Gong Y, Hopewell JC, Johnson T, Kleber ME, Langaee TY, Li M, Li YR, Liu K, McDonough CW, Meijs MF, Middelberg RP, Musunuru K, Nelson CP, O'Connell JR, Padmanabhan S, Pankow JS, Pankratz N, Rafelt S, Rajagopalan R, Romaine SP, Schork NJ, Shaffer J, Shen H, Smith EN, Tischfield SE, van der Most PJ, van Vliet-Ostaptchouk JV, Verweij N, Volcik KA, Zhang L, Bailey KR, Bailey KM, Bauer F, Boer JM, Braund PS, Burt A, Burton PR, Buxbaum SG, Chen W, Cooper-Dehoff RM, Cupples LA, deJong JS, Delles C, Duggan D, Fornage M, Furlong CE, Glazer N, Gums JG, Hastie C, Holmes MV, Illig T, Kirkland SA, Kivimaki M, Klein R, Klein BE, Kooperberg C, Kottke-Marchant K, Kumari M, LaCroix AZ, Mallela L, Murugesan G, Ordovas J, Ouwehand WH, Post WS, Saxena R, Scharnagl H, Schreiner PJ, Shah T, Shields DC, Shimbo D, Srinivasan SR, Stolk RP, Swerdlow DI, Taylor HA Jr, Topol EJ, Toskala E, van Pelt JL, van Setten J, Yusuf S, Whittaker JC, Zwinderman AH; LifeLines Cohort Study, Anand SS, Balmforth AJ, Berenson GS, Bezzina CR, Boehm BO, Boerwinkle E, Casas JP, Caulfield MJ, Clarke R, Connell JM, Cruickshanks KJ, Davidson KW, Day IN, de Bakker PI, Doevendans PA, Dominiczak AF, Hall AS, Hartman CA, Hengstenberg C, Hillege HL, Hofker MH, Humphries SE, Jarvik GP, Johnson JA, Kaess BM, Kathiresan S, Koenig W, Lawlor DA, März W, Melander O, Mitchell BD, Montgomery GW, Munroe PB, Murray SS, Newhouse SJ, Onland-Moret NC, Poulter N, Psaty B, Redline S, Rich SS, Rotter JI, Schunkert H, Sever P, Shuldiner AR, Silverstein RL, Stanton A, Thorand B, Trip MD, Tsai MY, van der Harst P, van der Schoot E, van der Schouw YT, Verschuren WM, Watkins H, Wilde AA, Wolffenbuttel BH, Whitfield JB, Hovingh GK, Ballantyne CM, Wijmenga C, Reilly MP, Martin NG, Wilson JG, Rader DJ, Samani NJ, Reiner AP, Hegele RA, Kastelein JJ, Hingorani AD, Talmud PJ, Hakonarson H, Elbers CC, Keating BJ, Drenos F. Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet 2012;91:823-838.

2254 Abbasi-Moheb L, Mertel S, Gonsior M, Nouri-Vahid L, Kahrizi K, Cirak S, Wieczorek D, Motazacker MM, Esmaeeli-Nieh S, Cremer K, Weißmann R, TzschachA, Garshasbi M, Abedini SS, Najmabadi H, Ropers HH, Sigrist SJ, Kuss AW.  Mutations in NSUN2 cause autosomal recessive intellectual disability.  Am J Hum Genet 2012; 90(5): 847-855.

2253 Adhikari K, AlChawa T, Ludwig K, Mangold E, Laird N, Lange C. Is it rare or common?  Genet Epidemiol. 2012 Jul;36(5):419-29. doi: 10.1002/gepi.21637.

2252 Alhamdani, M.S.S., Youns, M., Buchholz, M., Gress, T.M., Beckers, M.C., Maréchal, D., Bauer, A.S., Schröder; C. & Hoheisel, J.D. Immunoassay-based proteome profiling of 24 pancreatic cancer cell lines.  J Proteomics 75, 3747-3759.

2251 Ali R, Campos B, Dyckhoff G, Haefeli WE, Herold-Mende C, Burhenne J.  Quantification of retinoid concentrations in human serum and brain tumor tissues. Anal Chim Acta. 2012 May 6;725:57-66. doi: 10.1016/j.aca.2012.03.003. Epub 2012 Mar 17.

2250 Ammar I, Izsvák Z, Ivics Z. The Sleeping Beauty transposon toolbox. Methods Mol Biol. 2012;859:229-40. doi: 10.1007/978-1-61779-603-6_13. PMID:22367875.

2249 Ammerpohl, O., Pratschke, J., Schafmayer, C., Haake, A., Faber, W., von Kampen, O., Brosch, M., Sipos, B., von Schönfels, W., Balschun, K., Röcken, C., Arlt, A., Schniewind, B., Grauholm, J., Kalthoff, H., Neuhaus, P., Stickel, F., Schreiber, S., Becker, T., Siebert, R. und Hampe, J.  Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma. Int J Cancer 130, 1319-1328. Epub 2011-07-21. 

2248  Anagnostopoulou P, Riederer B, Duerr J, Michel S, Binia A, Agrawal R, Liu X,Kalitzki K, Xiao F, Chen M, Schatterny J, Hartmann D, Thum T, Kabesch M,Soleimani M, Seidler U, Mall MA.  SLC26A9-mediated chloride secretion preventsmucus obstruction in airway inflammation.  J Clin Invest. 2012 Oct1;122(10):3629-34. doi: 10.1172/JCI60429. Epub 2012 Sep 4. PubMed PMID: 22945630;PubMed Central PMCID: PMC3461899.

2247 Anders S, Sack B, Pohl A, Münte T, Pramstaller P, Klein C, Binkofski F.  Compensatory premotor activity during affective face processing in subclinical carriers of a single mutant Parkin allele.  Brain. 2012 Apr;135(Pt 4):1128-40. doi: 10.1093/brain/aws040. Epub 2012 Mar 20.

2246 Ardito CM, Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, DelGiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D , Briel T, Herner A, Trajkovic-Arsic M, Sipos B, Liou GY, Storz P, Murray NR, Threadgill DW, Sibilia M, Washington MK, Wilson CL, Schmid RM, Raines EW, Crawford HC, Siveke JT.  EGF Receptor is Required for Kras-induced Pancreatic Tumorigenesis.  Cancer Cell 2012 Sep; 11;22(3):304-17. doi: 10.1016/j.ccr.2012.07.024.

2245 Arnold M, Hartsperger ML, Baurecht H, Rodríguez E, Wachinger B, Franke A,Kabesch M, Winkelmann J, Pfeufer A, Romanos M, Illig T, Mewes HW, Stümpflen V,Weidinger S.  Network-based SNP meta-analysis identifies joint and disjointgenetic features across common human diseases.  BMC Genomics. 2012 Sep 18;13:490. doi: 10.1186/1471-2164-13-490. PubMed PMID: 22988944.

2244 Aronica E, Becker AJ, Spreafico R.  Malformations of cortical development.  Brain Pathology, 22(3):380-401, 2012.

2243 Asgharzadeh S, Salo JA, Ji L, Oberthuer A, Fischer M, Berthold F, Hadjidaniel M, Liu CW, Metelitsa LS, Pique-Regi R, Wakamatsu P, Villablanca JG, Kreissman SG, Matthay KK, Shimada H, London WB, Sposto R, Seeger RC. Clinical.

2242 Attarbaschi, A., Morak, M., Cario, G., Cazzaniga, G., Ensor, H.M., te Kronnie, G., Bradtke, J., Mann, G., Vendramini, E., Palmi, C, Schwab, C., Russell, L.J., Schrappe, M., Conter, V., Mitchell, C.D., Strehl, S., Zimmermann, M., Pötschger, U.,  Harrison, C.J., Stanulla, M., Panzer-Grümayer, R., Haas, O.A., Moorman, A.V. on behalf of the Associazione Italiana di Ematologia ed Oncologia Pediatrica (AIEOP)-Berlin-Frankfurt-Münster (BFM) Study Group and National Cancer Research Institute (NCRI)-Children's Cancer and Leukemia (CCLG) Study Group.  Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukemia: A comparative analysis of the AIEOP-BFM and UK NCRI-CCLG Study Groups.  Br J Haematol. 2012, 158:772-7.

2241 Auburger G, Klinkenberg M, Drost J, Marcus K, Morales-Gordo B, Kunz WS, Brandt U, Broccoli V, Reichmann H, Gispert S, Jendrach M. Primary Skin Fibroblasts as a Model of Parkinson's Disease. Mol Neurobiol. 2012 Feb 19. [Epub ahead of print]

2240 Augustin R, Endres K, Reinhardt S, Kuhn PH, Lichtenthaler SF, Hansen J, Wurst W, Trümbach D.  Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10. BMC Med Genet. 2012 May 17;13:35.

2239 Aydin, D., Weyer, S. W. and Müller, UC.  Functions of the APP gene family in the nervous system: insights from mouse models.   Exp Brain Res 217, 365.

2238 Balss J, Pusch S, Beck AC, Herold-Mende C, Krämer A, Thiede C, Buckel W, Langhans CD, Okun JG, von Deimling A.  Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate. Acta Neuropathol. 2012 Dec;124(6):883-91.

2237 Barkus C, Michael Feyder, Carolyn Graybeal, Tara Wright, Lisa Wiedholz, Alicia Izquierdo, Carly Kiselycznyk, Wolfram Schmitt, David J. Sanderson, J. Nicholas P. Rawlins, Lisa M. Saksida, Timothy J. Bussey, Rolf Sprengel, David Bannerman & Andrew Holmes  Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?   Neuropharmacology 62, 1263-1272.

2236 Basel-Vanagaite L, Dallapiccola B, Ramirez-Solis R, Segref A, Thiele H, Edwards A, Arends MJ, Miró X, White JK, Désir J, Abramowicz M, Dentici ML, Lepri F, Hofmann K, Har-Zahav A, Ryder E, Karp NA, Estabel J, Gerdin AK, Podrini C, Ingham NJ, Altmüller J, Nürnberg G, Frommolt P, Abdelhak S, Pasmanik-Chor M, Konen O, Kelley RI, Shohat M, Nürnberg P, Flint J, Steel KP, Hoppe T, Kubisch C, Adams DJ, Borck G.  Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome.  Am J Hum Genet. 2012 Dec 7;91(6):998-1010. doi: 10.1016/j.ajhg.2012.10.011. Epub 2012 Nov 29.

2235 Batra R, Harder N, Gogolin S, Diessl N, Soons Z, Jäger-Schmidt C, Lawerenz C, Eils R, Rohr K, Westermann F, König R.  Time-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdown.  PLoS One. 2012;7(12):e50988. doi:10.1371/journal.pone.0050988. Epub 2012 Dec 12. PubMed PMID: 23251412; PubMed Central PMCID: PMC3521006.

2234 Bauer AS, Keller, A., Costello-Goldring, E., Greenhalf, W., Bier, M., Borries, A., Beier, M., Neoptolemos, J.P., Büchler, M., Werner, J., Giese, N. & Hoheisel, J.D. Diagnosis of pancreatic ductal adenocarcinoma and chronic pancreatitis by measurement of microrna abundance in blood and tissue. PLoS ONE 7, e34151.

2233 Beck A, Wüstenberg T, Genauck A, Wrase J, Schlagenhauf F, Smolka MN, Mann K, Heinz A.  Effect of brain structure, brain function, and brain connectivity on relapse in alcohol-dependent patients. Arch Gen Psychiatry. 2012 Aug;69(8):842-52. doi: 10.1001/archgenpsychiatry.2011.2026.

2232 Becker K, Di Donato N, Holder-Espinasse M, Andrieux J, Cuisset JM, Vallée L, Plessis G, Jean N, Delobel B, Thuresson AC, Annerén G, Ravn K, Tümer Z, Tinschert S, Schrock E, Jønch AE, Hackmann K.  De novo microdeletions of chromosome 6q14.1-q14.3 and 6q12.1-q14.1 in two patients with intellectual disability - further delineation of the 6q14 microdeletion syndrome and review of the literature.  Eur J Med Genet. 2012 Apr 12. PMID:22561202.

2230 Beetz, Christian, Thomas Pieber, Nicole Hertel, Maria Schabhüttl, Carina Fischer, Slave Trajanovski, Elisabeth Graf, Silke Keiner, Ingo Kurth, Thomas Wieland, Rita-Eva Varga, Vincent Timmerman, Mary M. Reilly, Tim M Strom, Michaela Auer-Grumbach. A gain-of-function mutation defines REEP1 as a novel gene for autosomal dominant hereditary motor neuropathy type V.  Am J Hum Genet, in press. 

2229 Beier CP, Kumar P, Meyer K, Leukel P, Bruttel V, Aschenbrenner I, Riemenschneider M, Fragoulis A, Rümmele P, Lamszus K, Schulz JB, Weis J, Bogdahn U, Wischhusen J, Hau P, Spang R, Beier D.S The Cancer Stem Cell Subtype Determines Immune Infiltration of Glioblastoma. Stem Cells Dev. 2012 Oct 10;21(15):2753-61.

2228 Beier D, Schriefer B, Brawanski K, Hau P, Weis J, Schulz JB, Beier CP. Efficacy of clinically relevant temozolomide dosing schemes in glioblastoma cancer stem cell lines. J Neurooncol. 2012 Aug;109(1):45-52. Epub 2012 Apr 29.

2227 Berg D, Wolff C, Malinowsky K, Tran K, Walch A, Bronger H, Schuster T, Höfler H, Becker KF. Profiling signalling pathways in formalin-fixed and paraffin-embedded breast cancer tissues reveals cross-talk between EGFR, HER2, HER3 and uPAR. J Cell Physiol. 2012 Jan;227(1):204-12. doi: 10.1002/jcp.22718.

2226 Berkel, S., Tang, W., Treviño, M., Vogt, M., Gass, P., Scherer, S. W., Sprengel, R., Schratt, G., Rappold, G. A. SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and can be linked to physiological effects.  Hum. Mol. Genet. 2012, 21:344-57.

2225 Bieschke J, Herbst M, Wiglenda T, Friedrich RP, Boeddrich A, Schiele F, Kleckers D, Lopez Del Amo JM, Gruening BA, Wang Q, Schmidt MR, Lurz R, Anwyl R, Schnoegl S, Faendrich M, Frank RF, Reif B, Guenther S, Walsh DM, Wanker EE. Small-molecule conversion of toxic oligomers to nontoxic {beta}-sheet-rich amyloid fibrils. Nat Chemical Biology 8 (1): 93-101.

2224 Binia A, Kabesch M.  Respiratory medicine - genetic base for allergy andasthma.  Swiss Med Wkly. 2012 Aug 22;142:w13612. doi: 10.4414/smw.2012.13612.Review. PubMed PMID: 22915201.

2223 Bis JC. et al., Enhancing Neuro Imaging Genetics through Meta-Analysis (ENIGMA) Consortium (2012).  Common variants at 12q14 and 12q24 are associated with hippocampal volume.  Nat Genetics, 44 (5): 545-551.

2222 Bisping E, Ikeda S, Sedej M, Wakula P, McMullen JR, Tarnavski O, Sedej S, Izumo S, Pu WT, Pieske B.  Transcription factor GATA4 is activated but not required for insulin like growth factor 1-induced cardiac hypertrophy. J Biol Chem. 2012 Jan 6. [Epub ahead of print].

2221  Bock, C. and T. Lengauer Managing drug resistance in cancer: lessons from HIV therapy.  Nat Rev Cancer, 2012. 12(7): p. 494-501. 

2220  Bonilla WV, A. Fröhlich, K. Senn, S. Kallert, M. Fernandez, S. Johnson, M. Kreutzfeldt, A. N. Hegazy, C. Schrick, P. G. Fallon, R. Klemenz, S. Nakae, H. Adler, D. Merkler, M. Löhning and D. D. Pinschewer. The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses Science, 335 (2012): 984-989.

2219 Boraska V, Jeron?i? A, Colonna V, Southam L, Nyholt DR, Rayner NW, Perry JR, Toniolo D, Albrecht E, Ang W, Bandinelli S, Barbalic M, Barroso I, Beckmann JS, Biffar R, Boomsma D, Campbell H, Corre T, Erdmann J, Esko T, Fischer K, Franceschini N, Frayling TM, Girotto G, Gonzalez JR, Harris TB, Heath AC, Heid IM, Hoffmann W, Hofman A, Horikoshi M, Zhao JH, Jackson AU, Hottenga JJ, Jula A, Kähönen M, Khaw KT, Kiemeney LA, Klopp N, Kutalik Z, Lagou V, Launer LJ, Lehtimäki T, Lemire M, Lokki ML, Loley C, Luan J, Mangino M, Mateo Leach I, Medland SE, Mihailov E, Montgomery GW, Navis G, Newnham J, Nieminen MS, Palotie A, Panoutsopoulou K, Peters A, Pirastu N, Polasek O, Rehnström K, Ripatti S, Ritchie GR, Rivadeneira F, Robino A, Samani NJ, Shin SY, Sinisalo J, Smit JH, Soranzo N, Stolk L, Swinkels DW, Tanaka T, Teumer A, Tönjes A, Traglia M, Tuomilehto J, Valsesia A, van Gilst WH, van Meurs JB, Smith AV, Viikari J, Vink JM, Waeber G, Warrington NM, Widen E, Willemsen G, Wright AF, Zanke BW, Zgaga L; Wellcome Trust Case Control Consortium, Boehnke M, d'Adamo AP, de Geus E, Demerath EW, den Heijer M, Eriksson JG, Ferrucci L, Gieger C, Gudnason V, Hayward C, Hengstenberg C, Hudson TJ, Järvelin MR, Kogevinas M, Loos RJ, Martin NG, Metspalu A, Pennell CE, Penninx BW, Perola M, Raitakari O, Salomaa V, Schreiber S, Schunkert H, Spector TD, Stumvoll M, Uitterlinden AG, Ulivi S, van der Harst P, Vollenweider P, Völzke H, Wareham NJ, Wichmann HE, Wilson JF, Rudan I, Xue Y, Zeggini E. Genome-wide meta-analysis of common variant differences between men and women. Hum Mol Genet. 2012 Nov 1;21(21):4805-15. doi: 10.1093/hmg/dds304. Epub 2012 Jul 27. PubMed PMID: 22843499.

2218 Borck G, Shin BS, Stiller B, Mimouni-Bloch A, Thiele H, Kim JR, Thakur M, Skinner C, Aschenbach L, Smirin-Yosef P, Har-Zahav A, Nürnberg G, Altmüller J, Frommolt P, Hofmann K, Konen O, Nürnberg P, Munnich A, Schwartz CE, Gothelf D, Colleaux L, Dever TE, Kubisch C, Basel-Vanagaite L.  eIF2? mutation that disrupts eIF2 complex integrity links intellectual disability to impaired translation initiation. Mol Cell. 2012 Nov 30;48(4):641-6. doi: 10.1016/j.molcel.2012.09.005. Epub 2012 Oct 11.

2217 Börno ST, Fischer A, Kerick M, Fälth M, Laible M, Brase JC, Kuner R, Dahl A, Grimm C, Sayanjali B, Isau M, Röhr C, Wunderlich A, Timmermann B, Claus R, Plass C, Graefen M, Simon R, Demichelis F, Rubin MA, Sauter G, Schlomm T, Sültmann H, Lehrach H, Schweiger MR. Increase in genome-wide differential DNA methylation in TMPRSS2:ERG fusion negative prostate cancers with miRNA-26a hypermethylation. Cancer Discov. 2012 Nov;2(11):1024-35. doi: 10.1158/2159-8290.CD-12-0041. Epub 2012 Aug 28. 

2216  Botla, S.K., Gholami, A.M., Malekpour, M., Moskalev, E.A., Fallah, M., Jandaghi, P., Aghajani, A., Bondar, I.S., Omranipour, R., Malekpour, F., Mohajeri, A, Babadi, A.J., Sahin, Ö., Bubnov, V.V., Najmabadi, H., Hoheisel, J.D. & Riazalhosseini, Y.  Diagnostic values of GHSR DNA methylation pattern in breast cancer.  Breast Canc. Res. Treat. 135, 705-713. 

2215 Bradfield PJ, Taal HR, Timpson NJ, Scherag A, Lecoeur C, Warrington NM, Hypponen E, Holst C, Valcarcel B, Thiering E, Salem RM, Schumacher FR, Cousminer DL, Sleiman PMA, Zhao J, Berkowitz RI, Vimaleswaran KS, Jarick I, Pennell CE, Evans DM, Pourcain BS, Berry DJ, Mook-Kanamori DO, Hofman A, Rivadeinera F, Uitterlinden AG, van Duijn CM, van der Valk RJP, de Jongste DC, Postma DS, Boomsma DI, Gauderman WJ, Hassanein WT, Lindgren CM, Mägi R, Boreham CAG, Neville CE, Moreno LA, Elliott P, Pouta A, Hartikainen AL, Li M, Raitakari O, Lehtimäki T, Eriksson JG, Palotie A, Dallongeville J, Das S, Deloukas P, McMahon G, Ring SM, Kemp JP, Buxton JL, Blakemore AIF, Bustamante M, Guxens M, Hirschhorn JN, Gillman MW, Kreiner-Møller E, Bisgaard H, Gilliland FD, Heinrich J, Wheeler E, Barroso I, O'Rahilly S, Meirhaeghe A, Sørensen TIA, Power C, Palmer LJ, Hinney A, Widen E, Farooqi IS, McCarthy MI, Froguel P, Meyre D, Hebebrand J, Jarvelin MR, Jaddoe VWV, Smith GD, Hakonarson H, Grant SFA for the Early Growth Genetics (EGG) Consortium.  A genome-wide association meta-analysis identifies new childhood obesity loci.  Nat Genet 2012; 44(5): 526-531

2214 Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W. 3. The mammalian gene function resource: the International Knockout Mouse Consortium.  Mamm Genome. 2012 Oct;23(9-10):580-6. doi: 10.1007/s00335-012-9422-2. Epub 2012 Sep 12.

2213 Brenk R., D. Rauh. Change or be changed: Reflections of the workshop 'Future in Medicinal Chemistry'. Bioorg Med Chem, 2012, 20(12):3695-7.

2212  Breu J, Touma C, Hölter SM, Knapman A, Wurst W, Deussing JM.  Urocortin 2 modulates aspects of social behaviour in mice.  Behav Brain Res. 2012 Aug 1;233(2):331-6.

2211  Brockmann K, Hilker R, Pilatus U, Baudrexel S, Srulijes K, Magerkurth J, Hauser AK, Schulte C, Csoti I, Merten CD, Gasser T, Berg D, Hattingen E.  GBA-associated PD. Neurodegeneration, altered membrane metabolism, and lack of energy failure.  Neurology. 2012 Jul 17;79(3):213-20. doi: 10.1212/WNL.0b013e31825dd369.

2210  Brockschmidt A, Trost D, Peterziel H, Zimmermann K, Ehrler M, Grassmann H, Waha A, Stabenow D, Brockschmidt FF, Hoischen A, Kalla C, Waha A, Seifert G, Knolle PA, Latz E, Wolfgang Wick, Volkmar H. Hans, Alexander Pfeifer, Angel P, Hess J, Weber RG.  KIAA1797 encodes a novel focal adhesion protein with tumor suppressor function in human gliomas  Brain. 2012 Apr;135(Pt 4):1027-41. doi: 10.1093/brain/aws045. Epub 2012 Mar 16.

2209 Brosch M, von Schönfels W, Ahrens M, Nothnagel M, Krawczak M, Laudes M, Sipos B, Becker T, Schreiber S, Röcken C, Schafmayer C, Hampe J.  SFRS10--a splicing factor gene reduced in human obesity?  Cell Metab. 2012 Mar 7;15(3):265-6.

2208 Brosseron F, May C, Schoenebeck B, Tippler B, Woitalla D, Kauth M, Brockmann K, Meyer H E, Berg D, Bufe A, Marcus K. Stepwise isolation of human peripheral erythrocytes, T lymphocytes, and monocytes for blood cell proteomics.  Proteomics Clin Appl, 2012, 6:497-501.

2207 Brueckner LM, Sagulenko E, Hess EM, Zheglo D, Blumrich A, Schwab M, Savelyeva L.  Genomic rearrangements at the FRA2H common fragile site frequently involve non-homologous recombination events across LTR and L1(LINE) repeats.  Hum Genet. 2012 Apr 5.

2206 Brüggemann N, Külper W, Hagenah J, Bauer P, Pattaro C, Tadic V, Lohnau T, Winkler S, Tonnies H, Sprenger A, Pramstaller P, Rolfs A, Siebert R, Riess O, Vieregge P, Lohmann K, Klein C.  Autosomal dominant Parkinson?s disease in a large German pedigree.  Acta Neurol Scand 2012;126:129-137.

2205 Büchel F, Wrzodek C, Mittag F, Dräger A, Eichner J, Rodriguez N, Le Novère N, and Zell, A.  Qualitative translation of relations from BioPAX to SBML qual.  Bioinformatics, 2012. doi: 10.1093/bioinformatics/bts508.

2204 Burbulla LF, Krüger R.  The use of primary fibroblasts to monitor mitochondrial phenotypes in the field of Parkinson's disease.  J Vis Exp 68. pii: 4228. doi: 10.3791/4228.

2203 Butler E.K., Voigt, A., Lutz, A.K., Toegel, J.P., Gerhardt, E., Karsten, P., Falkenburger, B., Reinartz, A., Winklhofer, K.F., and Schulz, J.B. The Mitochondrial Chaperone Protein TRAP1 Mitigates ?-Synuclein Toxicity. PLoS Genetics, Feb;8(2):e1002488.

2202 Campos B., Warta R., Chaisaingmongkol J., Popanda O., Hartmann C., von Deimling A., Unterberg A., Plass C., Schmezer P., Herold-Mende C.  Epigenetically Mediated Down-regulation of the Differentiation-Promoting Chaperon Protein CRABP2 in Astrocytic Gliomas  Int J Cancer. 2012 Oct 15;131(8):1963-8. doi: 10.1002/ijc.27446. Epub 2012 Mar 8.

2201 Cancer Genome Atlas Research Network.  Comprehensive genomic characterization of squamous cell lung cancers.  Nature. 2012 Sep 27;489(7417):519-25. doi: 10.1038/nature11404. Epub 2012 Sep 9. Erratum in: Nature. 2012 Nov 8;491(7423):288. Rogers, Kristen [corrected to Rodgers, Kristen].

2200 CARDIoGRAMplusC4D Consortium, Deloukas P, Kanoni S, Willenborg C, Farrall M, Assimes TL, Thompson JR, Ingelsson E, Saleheen D, Erdmann J, Goldstein BA, Stirrups K, König IR, Cazier JB, Johansson A, Hall AS, Lee JY, Willer CJ, Chambers JC, Esko T, Folkersen L, Goel A, Grundberg E, Havulinna AS, Ho WK, Hopewell JC, Eriksson N, Kleber ME, Kristiansson K, Lundmark P, Lyytikäinen LP, Rafelt S, Shungin D, Strawbridge RJ, Thorleifsson G, Tikkanen E, Van Zuydam N, Voight BF, Waite LL, Zhang W, Ziegler A, Absher D, Altshuler D, Balmforth AJ, Barroso I, Braund PS, Burgdorf C, Claudi-Boehm S, Cox D, Dimitriou M, Do R; DIAGRAM Consortium; CARDIOGENICS Consortium, Doney AS, El Mokhtari N, Eriksson P, Fischer K, Fontanillas P, Franco-Cereceda A, Gigante B, Groop L, Gustafsson S, Hager J, Hallmans G, Han BG, Hunt SE, Kang HM, Illig T, Kessler T, Knowles JW, Kolovou G, Kuusisto J, Langenberg C, Langford C, Leander K, Lokki ML, Lundmark A, McCarthy MI, Meisinger C, Melander O, Mihailov E, Maouche S, Morris AD, Müller-Nurasyid M; MuTHER Consortium, Nikus K, Peden JF, Rayner NW, Rasheed A, Rosinger S, Rubin D, Rumpf MP, Schäfer A, Sivananthan M, Song C, Stewart AF, Tan ST, Thorgeirsson G, van der Schoot CE, Wagner PJ; Wellcome Trust Case Control Consortium, Wells GA, Wild PS, Yang TP, Amouyel P, Arveiler D, Basart H, Boehnke M, Boerwinkle E, Brambilla P, Cambien F, Cupples AL, de Faire U, Dehghan A, Diemert P, Epstein SE, Evans A, Ferrario MM, Ferrières J, Gauguier D, Go AS, Goodall AH, Gudnason V, Hazen SL, Holm H, Iribarren C, Jang Y, Kähönen M, Kee F, Kim HS, Klopp N, Koenig W, Kratzer W, Kuulasmaa K, Laakso M, Laaksonen R, Lee JY, Lind L, Ouwehand WH, Parish S, Park JE, Pedersen NL, Peters A, Quertermous T, Rader DJ, Salomaa V, Schadt E, Shah SH, Sinisalo J, Stark K, Stefansson K, Trégouët DA, Virtamo J, Wallentin L, Wareham N, Zimmermann ME, Nieminen MS, Hengstenberg C, Sandhu MS, Pastinen T, Syvänen AC, Hovingh GK, Dedoussis G, Franks PW, Lehtimäki T, Metspalu A, Zalloua PA, Siegbahn A, Schreiber S, Ripatti S, Blankenberg SS, Perola M, Clarke R, Boehm BO, O'Donnell C, Reilly MP, März W, Collins R, Kathiresan S, Hamsten A, Kooner JS, Thorsteinsdottir U, Danesh J, Palmer CN, Roberts R, Watkins H, Schunkert H, Samani NJ. Large-scale association analysis identifies new risk loci for coronary artery disease. Nat Genet. 2013 Jan;45(1):25-33.

2199 Carrera N, Arrojo M, Sanjuán J, Ramos-Rios R, Paz E, Suárez-Rama JJ, Páramo M, Agra S, Brenlla J, Martinez S, Rivero O, Collier DA, Palotie A, Cichon S, Nöthen MM, Rietschel M, Rujescu D, Stefansson H, Steinberg S, Sigurdsson E, Clair DS, Tosato S, Werge T, Stefansson K, González JC, Valero J, Gutiérrez-Zotes A, Labad A, Martorell L, Vilella E, Carracedo A, Costas J Association study of nonsynonymous single nucleotide polymorphisms in schizophrenia.  Biol Psychiatry 71:169-177. doi.org/10.1016/j.biopsych.2011.09.032.

2198 Casaca VI, Illi S, Suttner K, Schleich I, Ballenberger N, Klucker E, Turan E, von Mutius E, Kabesch M, Schaub B.  TBX21 and HLX1 polymorphisms influencecytokine secretion at birth.  PLoS One. 2012;7(1):e31069. Epub 2012 Jan 30. PubMedPMID: 22303482; PubMed Central PMCID: PMC3268767.

2197 Chao Y, Papenfort K, Reinhardt R, Sharma CM, Vogel J. An atlas of Hfq-bound transcripts reveals 3' UTRs as a genomic reservoir of regulatory small RNAs. EMBO Journal 31(29):4005-19

2196 Charlet K, Schlagenhauf F, Richter A, Naundorf K, Dornhof L, Weinfurtner C, König F, Walaszek B, Schubert F, Müller CA, Gutwinski S, Seissinger A, Schmitz L, Walter H, Beck A, Gallinat J, Kiefer F, Heinz A. Neural activation during processing of aversive faces predicts treatment outcome in alcoholism.  Addiction Biology [Epub ahead of print]

2195 Charlet K, Schlagenhauf F, Richter A, Walter H, Beck A, Gallinat J, Kiefer F, Heinz A.  Neuronale Aktivierung während der Verarbeitung negativer Gesichtsausdrücke prädiziert Abstinenzdauer in alkoholabhängigen Patienten.  Sucht: Volume 58 (2012), Supplement 1, Page 114.

2194 Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa MF, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson A, Tönjes A, Dehghan A, Lambert JC, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Coassin S, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; WTCCC2, Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu F, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Giulianini F, Koenig W, Illig T, Meisinger C, Gieger C, Zgaga L, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Stengel B, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki IB, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman J, Hayward C, Ridker PM, Parsa A, Bochud M, Heid IM, Kao WH, Fox CS, Köttgen A. Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Hum Mol Genet. 2012;21:5329-5343.

2193 Chen Z, Gerhold-Ay A, Gebhard S, Boehm D, Solbach C, Lebrecht A, Battista M,Sicking I, Cotarelo C, Cadenas C, Marchan R, Stewart JD, Gehrmann M, Koelbl H,Hengstler JG, Schmidt M.  Immunoglobulin kappa C predicts overall survival innode-negative breast cancer.   PLoS One. 2012;7(9):e44741. doi:10.1371/journal.pone.0044741. Epub 2012 Sep 28.

2192 Chmielecki J, Peifer M, Viale A, Hutchinson K, Giltnane J, Socci ND, Hollis CJ, Dean RS, Yenamandra A, Jagasia M, Kim AS, Davé UP, Thomas RK, Pao W.  Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.  Genes Chromosomes Cancer. 2012 Jan;51(1):54-65. doi: 10.1002/gcc.20930. Epub 2011 Sep 21.

2191 Christoforou A, Dondrup M, Mattingsdal M, Mattheisen M, Giddaluru S, Nöthen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Jonassen I, Steen VM, Puntervoll P, Le Hellard S. Linkage-Disequilibrium-Based Binning Affects the Interpretation of GWASs. Am J Hum Genet. 2012 Apr 6;90(4):727-33. Epub 2012 Mar 22.

2190 Chua JJ, Butkevich E, Worseck JM, Kittelmann M, Grønborg M, Behrmann E, Stelzl U, Pavlos NJ, Lalowski MM, Eimer S, Wanker EE, Klopfenstein DR, Jahn R.  Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter.  Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5862-7.

2189 Cirstea IC, Gremer L, Dvorsky R, Zhang SC, Piekorz RP, Zenker M, Ahmadian MR. Diverging gain-of-function mechanisms of two novel KRAS mutations associated with Noonan and cardio-facio-cutaneous syndromes.  Hum Mol Genet 22, 262-270. PMID: 23059812

2188 Clarke TK, Dempster E, Docherty SJ, Desrivieres S, Lourdsamy A, Wodarz N, Ridinger M, Maier W, Rietschel M, Schumann G.  Multiple polymorphisms in genes of the adrenergic stress system confer vulnerability to alcohol abuse.  Addict Biol. 2012 Jan;17(1):202-8. doi: 10.1111/j.1369-1600.2010.00263.

2187 Cleynen I, González JR, Figueroa C, Franke A, McGovern D, Bortlík M, Crusius BJ, Vecchi M, Artieda M, Szczypiorska M, Bethge J, Arteta D, Ayala E, Danese S, van Hogezand RA, Panés J, Peña SA, Lukas M, Jewell DP, Schreiber S, Vermeire S, Sans M. Genetic factors conferring an increased susceptibility to develop Crohn's disease also influencedisease phenotype: results from the IBDchip European Project.<http://www.ncbi.nlm.nih.gov/pubmed/23263249> Gut. 2012 Dec 21. [Epub ahead of print].

2186 Coco S, Theissen J, Scaruffi P, Stigliani S, Moretti S, Oberthuer A, Valdora F, Fischer M, Gallo F, Hero B, Bonassi S, Berthold F & Tonini GP Age-dependent accumulation of genomic aberrations and deregulation of cell cycle and telomerase genes in metastatic neuroblastoma.  Int J Cancer, 2012, 131(7): 1591-1600.

2185 Collins AL, Kim Y, Szatkiewicz JP, Bloom RJ, Hilliard CE, Quackenbush CR, Meier S, Rivas F, Mayoral F, Cichon S, Nöthen MM, Rietschel M, Sullivan PF.  Identifying bipolar disorder susceptibility loci in a densely affected pedigree.  Mol Psychiatry. 2012 Dec 18. doi: 10.1038/mp.2012.176.

2184 Corcoran CP, Rieder R, Podkaminski D, Hofmann B, Vogel J. Use of aptamer tagging to identify in vivo Protein binding partners of small regulatory RNAs Methods in Molecular Biology 905:177-200 

2183 Cruz FP, C. Martin, K. Buchholz K, M.J. Lafuente-Monasterio, T. Rodrigues, B. Sönnichsen, R. Moreira, F.J. Gamo, M. Marti, M.M. Mota, M. Hannus, M. Prudêncio. Drug Screen Targeted at Plasmodium Liver Stages Identifies a Potent Multi-Stage Anti-Malarial Drug J Inf Dis., 205, 1278-1286

2182 Dalke C., Gabriele Hölzlwimmer, Julia Calzada-Wack, Leticia Quintanilla-Martinez, Michael J Atkinson and Michael Rosemann (2012): Differences in the Susceptibility to Iodine131-induced Thyroid Tumours amongst Inbred Mouse Strains.   J Radiat Res. doi:10.1269/jrr.11182.

2181 Danhauser K, Sauer SW, Haack TB, Wieland T, Staufner C, Graf E, Zschocke J, Strom TM, Traub T, Okun JG, Meitinger T, Hoffmann GF, Prokisch H, Kölker S. DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria. Am J Hum Genet. 2012 Dec 7;91(6):1082-7.

2180 Dastani Z, Hivert MF, Timpson N, Perry JR, Yuan X, Scott RA, Henneman P, Heid IM, Kizer JR, Lyytikainen LP, Fuchsberger C, Tanaka T, Morris AP, Small K, Isaacs A, Beekman M, Coassin S, Lohman K, Qi L, Kanoni S, Pankow JS, Uh HW, Wu Y, Bidulescu A, Rasmussen-Torvik LJ, Greenwood CM, Ladouceur M, Grimsby J, Manning AK, Liu CT, Kooner J, Mooser VE, Vollenweider P, Kapur KA, Chambers J, Wareham NJ, Langenberg C, Frants R, Willems-Vandijk K, Oostra BA, Willems SM, Lamina C, Winkler TW, Psaty BM, Tracy RP, Brody J, Chen I, Viikari J, Kahonen M, Pramstaller PP, Evans DM, St Pourcain B, Sattar N, Wood AR, Bandinelli S, Carlson OD, Egan JM, Bohringer S, van Heemst D, Kedenko L, Kristiansson K, Nuotio ML, Loo BM, Harris T, Garcia M, Kanaya A, Haun M, Klopp N, Wichmann HE, Deloukas P, Katsareli E, Couper DJ, Duncan BB, Kloppenburg M, Adair LS, Borja JB, Wilson JG, Musani S, Guo X, Johnson T, Semple R, Teslovich TM, Allison MA, Redline S, Buxbaum SG, Mohlke KL, Meulenbelt I, Ballantyne CM, Dedoussis GV, Hu FB, Liu Y, Paulweber B, Spector TD, Slagboom PE, Ferrucci L, Jula A, Perola M, Raitakari O, Florez JC, Salomaa V, Eriksson JG, Frayling TM, Hicks AA, Lehtimaki T, Smith GD, Siscovick DS, Kronenberg F, van Duijn C, Loos RJ, Waterworth DM, Meigs JB, Dupuis J, Richards JB, Voight BF, Scott LJ, Steinthorsdottir V, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Hofmann OM, Segre AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bostrom KB, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jorgensen T, Kao WH, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Petersen AK, Platou C, Proenca C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparso T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Morris AD, Palmer CN, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Pedersen O, Barroso I, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI, Soranzo N, Wheeler E, Glazer NL, Bouatia-Naji N, Magi R, Randall J, Elliott P, Rybin D, Dehghan A, Hottenga JJ, Song K, Goel A, Lajunen T, Doney A, Cavalcanti-Proenca C, Kumari M, Timpson NJ, Zabena C, Ingelsson E, An P, O'Connell J, Luan J, Elliott A, Roccasecca RM, Pattou F, Sethupathy P, Ariyurek Y, Barter P, Beilby JP, Ben-Shlomo Y, Bergmann S, Bochud M, Bonnefond A, Borch-Johnsen K, Bottcher Y, Brunner E, Bumpstead SJ, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Crisponi L, Day IN, de Geus EJ, Delplanque J, Fedson AC, Fischer-Rosinsky A, Forouhi NG, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Grundy S, Gwilliam R, Hallmans G, Hammond N, Han X, Hartikainen AL, Hayward C, Heath SC, Hercberg S, Hillman DR, Hingorani AD, Hui J, Hung J, Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P, Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Mahley R, Mangino M, Martinez-Larrad MT, McAteer JB, McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Mukherjee S, Naitza S, Neville MJ, Orru M, Pakyz R, Paolisso G, Pattaro C, Pearson D, Peden JF, Pedersen NL, Pfeiffer AF, Pichler I, Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Rice K, Ripatti S, Rivadeneira F, Rolandsson O, Sandbaek A, Sandhu M, Sanna S, Sayer AA, Scheet P, Seedorf U, Sharp SJ, Shields B, Sigurethsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, Sovio U, Swift A, Syddall H, Syvanen AC, Tonjes A, Uitterlinden AG, van Dijk KW, Varma D, Visvikis-Siest S, Vitart V, Vogelzangs N, Waeber G, Wagner PJ, Walley A, Ward KL, Watkins H, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC, Borecki IB, Meneton P, Magnusson PK, Nathan DM, Williams GH, Silander K, Bornstein SR, Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Serrano-Rios M, Lind L, Palmer LJ, Hu FBs, Franks PW, Ebrahim S, Marmot M, Wright AF, Stumvoll M, Hamsten A, Buchanan TA, Valle TT, Rotter JI, Penninx BW, Boomsma DI, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR, Peltonen L, Mooser V, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Chasman DI, Johansen CT, Fouchier SW, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Feitosa MF, Orho-Melander M, Melander O, Li X, Cho YS, Go MJ, Kim YJ, Lee JY, Park T, Kim K, Sim X, Ong RT, Croteau-Chonka DC, Lange LA, Smith JD, Ziegler A, Zhang W, Zee RY, Whitfield JB, Thompson JR, Surakka I, Smit JH, Sinisalo J, Scott J, Saharinen J, Sabatti C, Rose LM, Roberts R, Rieder M, Parker AN, Pare G, O'Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, McArdle W, Masson D, Martin NG, Marroni F, Lucas G, Luben R, Lokki ML, Lettre G, Launer LJ, Lakatta EG, Laaksonen R, Konig IR, Khaw KT, Kaplan LM, Johansson A, Janssens AC, Igl W, Hovingh GK, Hengstenberg C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Groop LC, Gonzalez E, Freimer NB, Erdmann J, Ejebe KG, Doring A, Dominiczak AF, Demissie S, de Faire U, Caulfield MJ, Boekholdt SM, Assimes TL, Quertermous T, Seielstad M, Wong TY, Tai ES, Feranil AB, Kuzawa CW, Taylor HA, Jr., Gabriel SB, Holm H, Gudnason V, Krauss RM, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJ, Schadt EE, Strachan DP, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, Kathiresan S (2012) Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 8: e1002607. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 2012;8(3):e1002607. doi: 10.1371/journal.pgen.1002607. Epub 2012 Mar 29.

2179 Davies RW, Wells GA, Stewart AF, Erdmann J, Shah SH, Ferguson JF, Hall AS, Anand SS, Burnett MS, Epstein SE, Dandona S, Chen L, Nahrstaedt J, Loley C, Konig IR, Krauss WE, Granger CB, Engert JC, Hengstenberg C, Wichmann HE, Schreiber S, Tang WH, Ellis SG, Rader DJ, Hazen SL, Reilly MP, Samani NJ, Schunkert H, Roberts R, McPherson R. A Genome Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex. Circ Cardiovasc Genet. 2012 doi: CIRCGENETICS.111.961243 [pii]10.1161/CIRCGENETICS.111.961243

2178 Davison LJ, Wallace C, Cooper JD, Cope NF, Wilson NK, Smyth DJ, Howson JM, Saleh N, Al-Jeffery A, Angus KL, Stevens HE, Nutland S, Duley S, Coulson RM, Walker NM, Burren OS, Rice CM, Cambien F, Zeller T, Munzel T,Lackner K, Blankenberg S; Cardiogenics Consortium, Fraser P, Gottgens B, Todd JA, Attwood T, Belz S, Braund P, Cambien F, Cooper J, Crisp-Hihn A, Diemert P, Deloukas P, Foad N, Erdmann J, Goodall AH, Gracey J, Gray E,Gwilliams R, Heimerl S, Hengstenberg C, Jolley J, Krishnan U, Lloyd-Jones H, Lugauer I, Lundmark P, Maouche S, Moore JS, Muir D, Murray E, Nelson CP, Neudert J, Niblett D, O'Leary K, Ouwehand WH, Pollard H, Rankin A, RiceCM, Sager H, Samani NJ, Sambrook J, Schmitz G, Scholz M, Schroeder L, Schunkert H, Syvannen AC, Tennstedt S, Wallace C. Long-range DNA looping and Gene expression analyses identify DEXI as an autoimmune disease candidate gene. Hum Mol Genet. 2012 Jan 15;21(2):322-33.

2177 De Brouwer S, Mestdagh P, Lambertz I, Pattyn F, De Paepe A, Westermann F, Schroeder C, Schulte JH, Schramm A, De Preter K, Vandesompele J, Speleman F. Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma. Int J Cancer. 2012 Jun 1;130(11):2591-8. doi: 10.1002/ijc.26295. Epub 2011 Aug 30.

2176 de Jong S, van Eijk KR, Zeegers DW, Strengman E, Janson E, Veldink JH, van den Berg LH, Cahn W, Kahn RS, Boks MP, Ophoff RA; The PGC Schizophrenia (GWAS) Consortium: St Clair D, Cichon S, Rietschel M, Nöthen MM, Maier W, Schulze TG, Mattheisen M, Kirov GK, O'Donovan MC, Holmans PA, Georgieva L, Nikolov I, Williams HJ, Toncheva D, Milanova V, Owen MJ, O'Donovan MC, Craddock N, Holmans PA, Hamshere M, Williams HJ, Moskvina V, Dwyer S, Georgieva L, Zammit S, Owen MJ, Kirov GK, Sullivan PF, Lin DY, van den Oord E, Kim Y, Stroup T, Lieberman JA, Hansen T, Ingason A, Olsen L, Schmock H, Skjødt C, Thygesen JH, Rosengren A, Werge T, Morris DW, O'Dushlaine CT, Kenny E, Quinn EM, Gill M, Corvin A, Blackwood DH, McGhee KA, Pickard B, Malloy P, Maclean AW, McIntosh A, Gejman PV, Sanders AR, Duan J, Levinson DF, Shi J, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, Cloninger C, Giegling I, Hartmann AM, Konnerth H, Friedl M, Konte B, Muglia P, Rujescu D, Pato MT, Pato CN, Fanous A, Hultman CM, Lichtenstein P, Bergen SE, Purcell S, Scolnick E, Sklar P, Sullivan PF, Djurovic S, Mattingsdal M, Agartz I, Melle I, Andreassen OA, Ophoff RA, Cantor RM, Freimer NB, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I, Strengman E, McQuillin A, Choudhury K, Datta S, Pimm J, Thirumalai S, Puri V, Krasucki R, Lawrence J, Quested D, Bass N, Gurling H, Malhotra AK, Lencz T.  Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes.  Eur J Hum Genet. 2012 Sep;20(9):1004-8. doi: 10.1038/ejhg.2012.38.

2175  Dedic N, Touma C, Romanowski CP, Schieven M, Kühne C, Ableitner M, Lu A, Holsboer F, Wurst W, Kimura M, Deussing JM. Assessing Behavioural Effects of Chronic HPA Axis Activation Using Conditional CRH-Overexpressing Mice. Cell Mol Neurobiol.  2012 Jul;32(5):815-28. Epub 2011 Dec 25.

2174 Degenhardt F, Priebe L, Herms S, Mattheisen M, Mühleisen TW, Meier S, Moebus S, Stroh maier J, Groß M, Breuer R, Lange C, Hoffmann P, Meyer-Lindenberg A, Heinz A, Walter H, Lucae S, Wolf C, Müller-Myhsok B, Holsboer F, Maier W, Rietschel M, Nöthen MM, Cichon S. Association between copy number variants in 16p11.2 and major depressive disorder in a German case-control sample. Am J Med Genet B Neuropsychiatr Genet. 2012 Apr;159B(3):263-73. doi: 10.1002/ajmg.b.32034. Epub 2012 Feb 17.

2173 Dehorter N, Lozovaya N, Mdzomba BJ, Michel FJ, Lopez C, Tsintsadze V, Tsintsadze T, Klinkenberg M, Gispert S, Auburger G, Hammond C. Subthalamic lesion or levodopa treatment rescues giant GABAergic currents of PINK1-deficient striatum. J Neurosci. 2012 Dec 12;32(50):18047-53.

2172 Demirkan A, van Duijn CM, Ugocsai P, Isaacs A, Pramstaller PP, Liebisch G, Wilson JF, Johansson Å, Rudan I, Aulchenko YS, Kirichenko AV, Janssens AC, Jansen RC, Gnewuch C, Domingues FS, Pattaro C, Wild SH, Jonasson I, Polasek O, Zorkoltseva IV, Hofman A, Karssen LC, Struchalin M, Floyd J, Igl W, Biloglav Z, Broer L, Pfeufer A, Pichler I, Campbell S, Zaboli G, Kolcic I, Rivadeneira F, Huffman J, Hastie ND, Uitterlinden A, Franke L, Franklin CS, Vitart V; DIAGRAM Consortium, Nelson CP, Preuss M; CARDIoGRAM Consortium, Bis JC, O'Donnell CJ, Franceschini N; CHARGE Consortium, Witteman JC, Axenovich T, Oostra BA, Meitinger T, Hicks AA, Hayward C, Wright AF, Gyllensten U, Campbell H, Schmitz G; EUROSPAN consortium. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet. 2012;8(2):e1002490.

2171 Derks EM, Vorstman JA, Ripke S, Kahn RS; Schizophrenia Psychiatric Genomic Consortium (Craddock N, Holmans PA, Hamshere M, Williams HJ, Moskvina V, Dwyer S, Georgieva L, Zammit S, Owen MJ, Sullivan PF, Lin DY, van den Oord E, Kim Y, Stroup TS, Lieberman JA, St Clair D, Kirov GK, O'Donovan MC, Holmans PA, Georgieva L, Nikolov I, Williams HJ, Toncheva D, Milanova V, Owen MJ, Morris DW, O'Dushlaine CT, Kenny E, Quinn EM, Gill M, Corvin A, Blackwood DH, McGhee KA, Pickard B, Malloy P, Maclean AW, McIntosh A, McQuillin A, Choudhury K, Datta S, Pimm J, Thirumalai S, Puri V, Krasucki R, Lawrence J, Quested D, Bass N, Gurling H, Pato MT, Pato CN, Fanous A, Hultman CM, Lichtenstein P, Bergen SE, Purcell S, Scolnick E, Sklar P, Sullivan PF, Gejman PV, Sanders AR, Duan J, Levinson DF, Shi J, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Black DW, Silverman JM, Byerley WF, Cloninger C, Cichon S, Rietschel M, Nöthen MM, Maier W, Schulze TG, Mattheisen M, Hansen T, Olsen L, Jakobsen KD, Schmock H, Skjødt C, Rosengren A, Høffding LK, Thygersen JH, Vangkilde A, Werge T, Giegling I, Hartmann AM, Konnerth H, Friedl M, Konte B, Muglia P, Rujescu D, Djurovic S, Mattingsdal M, Agartz I, Melle I, Andreassen OA, Ophoff RA, Cantor RM, Freimer NB, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I, Strengman E, Malhotra AK, Lencz T, Ripke S, Daly MJ, Holmans PA, Lin DY, Purcell S, Dudbridge F, Neale BM, Rossin L, Visscher PM, Posthuma D, Ruderfer DM, Kendler KS, Fanous A, O'Donovan MC), Ophoff RA.  Investigation of the genetic association between quantitative measures of psychosis and schizophrenia: a polygenic risk score analysis.  PLoS One. 2012;7(6):e37852. doi: 10.1371/journal.pone.0037852.

2170 Di Benedetto B, Kühn R, Nothdurfter C, Rein T, Wurst W, Rupprecht R. N-desalkylquetiapine activates ERK1/2 to induce GDNF release in C6 glioma cells: a putative cellular mechanism for quetiapine as antidepressant. Neuropharmacology. 2012 Jan;62(1):209-16. Epub 2011 Jul 13.

2169 Di Donato N, Riess A, Hackmann K, Rump A, Huebner A, von der Hagen M, Hahn G, Schrock E, Tinschert S.  Macrocephaly, Obesity, Mental (intellectual) disability, and Ocular Abnormalities: alternative definition and further delineation of MOMO syndrome.  Am J Med Genet A. 2012 Nov;158A(11):2857-62. doi: 10.1002/ajmg.a.35481. Epub 2012 Jul 20.

2168 Ding L, Poser I, Paszkowski-Rogacz M, Buchholz F.  From RNAi Screens to Molecular Function in Embryonic Stem Cells. Stem Cell Rev Rep. 2012 Mar;8(1):32-42.

2167 Dittmer A, Förstemann K MCMV infection of cultured mouse cells induces expression of miR-7a.  J Gen Virol. Mar 21.

2166 Ditzen C, Tang N, Jastorff AM, Teplytska L, Yassouridis A, Maccarrone G, Uhr M, Bronisch T, Miller CA, Holsboer F, Turck CW.  Cerebrospinal fluid biomarkers for major Depression confirm relevance of associated pathophysiology.  Neuropsychopharmacology 2012 Mar, 37(4):1013-1025. doi: 10.1038/npp.2011.285.

2165 Dizier MH, Margaritte-Jeannin P, Madore AM, Esparza-Gordillo J, Moffatt M, Corda E, Monier F, Guilloud-Bataille M, Franke A, Weidinger S, Annesi-Maesano I, Just J, Pin I, Kauffmann F, Cookson W, Lee YA, Laprise C, Lathrop M, Bouzigon E, Demenais F. The ANO3/MUC15 locus is associated with eczema in families ascertained through Asthma.  J Allergy Clin Immunol 2012;129:1547-53.e3.

2164 Dolnik A, Engelmann JC, Scharfenberger-Schmeer M, Mauch J, Kelkenberg-Schade S, Haldemann B, Fries T, Krönke J, Kühn MWM, Paschka P, Kayser S, Wolf S, Gaidzik VI, Schlenk RF, Rücker FG, Döhner H, Lottaz C, Döhner K, Bullinger L.  Commonly altered genomic regions in acute myeloid leukemia are enriched for somatic mutations involved in chromatin-remodeling and splicing.  Blood. 2012;120:e83-92.

2163 Donahue LR, Hrabe de Angelis M, Hagn M, Franklin C, Lloyd KC, Magnuson T, McKerlie C, Nakagata N, Obata Y, Read S, Wurst W, Hörlein A, Davisson MT. (2012)  Centralized mouse repositories,  Mamm Genome. 23(9-10):559-71. doi: 10.1007/s00335-012-9420-4.

2162 Doncheva NT, Assenov Y, Domingues FS, Albrecht M.   Topological analysis and interactive visualization of biological networks and protein structures. Nat Protoc. 2012 Mar 15;7(4):670-85.

2161 Doncheva NT, Kacprowski T, Albrecht M. Recent approaches to the prioritization of candidate disease genes. Wiley Interdiscip Rev Syst Biol Med.  2012 Sep-Oct;4(5):429-42.

2160 Donlin LT, Andresen C, Just S, Rudensky E, Pappas CT, Kruger M, Jacobs EY, Unger A, Zieseniss A, Dobenecker MW, Voelkel T, Chait BT, Gregorio CC, Rottbauer W, Tarakhovsky A, Linke WA.  Smyd2 controls cytoplasmic lysine methylation of hsp90 and myofilament organization.  Genes Dev. 2012;26:114-119.

2159 Dreher F, Kreitler T, Hardt C, Kamburov A, Yildirimman R, Schellander K, Lehrach H, Lange BMH, Herwig R.  DIPSBC - Data Integration Platform for Systems Biology Collaborations.  BMC Bioinformatics. 2012 May 8;13:85. doi: 10.1186/1471-2105-13-85.

2158 Dueck A., Ziegler C., Eichner A., Berezikov E. & Meister G.  MicroRNAs associated with the different human Argonaute proteins.  Nucleic Acids Research, 40(19):9850-62.

2157 Dufour A, Schneider F, Hoster E, Benthaus T, Ksienzyk B, Schneider S, Kakadia PM, Sauerland MC, Berdel WE, Büchner T, Wörmann B, Braess J, Subklewe M, Hiddemann W, Bohlander SK, Spiekermann K, for the AML CG study group.  Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients.  Ann Hematol. 2012;91:1051-1063.

2156 Duitama J, McEwen GK, Huebsch T, Palczewski S, Schulz S, Verstrepen K, Suk E-K, and Hoehe MR:  Fosmid-based whole genome haplotyping of a HapMap trio child: Evaluation of Single Individual Haplotyping techniques.  Nucleic Acids Res 2012;40(5):2041-53. Epub 2011 Nov 18.

2155 Eißmann M, Melzer IM, Fernández SB, Michel G, Hrab? de Angelis M, Hoefler G, Finkenwirth P, Jauch A, Schoell B, Grez M, Schmidt M, Bartholomae CC, Newrzela S, Haetscher N, Rieger MA, Zachskorn C, Mittelbronn M, Zörnig M.  Overexpression of the anti-apoptotic protein AVEN contributes to increased malignancy in hematopoietic neoplasms. . Oncogene. 2012 Jul 2. doi: 10.1038/onc.2012.263.

2154 Ellinghaus D*, Folseraas T*, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK, Wijmenga C, Ponsioen CY, Mathew CG, Rutgeerts P, Vermeire S, Schrumpf E, Hov JR, Manns MP, Boberg KM, Schreiber S, Franke A, Karlsen TH.  Genome-wide association analysis in Primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4.  Hepatology. 2012 Jul 23. doi: 10.1002/hep.25977. [Epub ahead of print] PMID: 22821403.

2153 Ellinghaus D, Ellinghaus E, Nair RP, Stuart PE, Esko T, Metspalu A, Debrus S, Raelson JV, Tejasvi T, Belouchi M, West SL, Barker JN, Kõks S, Kingo K, Balschun T, Palmieri O, Annese V, Gieger C, Wichmann HE, Kabesch M, Trembath RC, Mathew CG, Abecasis GR, Weidinger S, Nikolaus S, Schreiber S, Elder JT, Weichenthal M, Nothnagel M, Franke A.  Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. Am J Hum Genet 2012; 90:636-47.

2152 Ellinghaus, E., Stanulla, M., Richter, G., Ellinghaus, D., te Kronnie, G., Cario, G., Cazzaniga, G., Horstmann, M., Panzer Grümayer, R., Cavé, H., Trka, J., Cinek, O., Teigler-Schlegel, A., ElSharawy, A., Häsler, R., Nebel, A., Meissner, B., Bartram, T., Lescai, F., Franceschi, C., Giordan, M., Nürnberg, P., Heinzow, B., Zimmermann, M., Schreiber, S., Schrappe, M., Franke, A. Identification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia. Leukemia. 2012, 26:902-9.

2151 Elsharawy A, Forster M, Schracke N, Keller A, Thomsen I, Petersen BS, Stade B, Stähler P, Schreiber S, Rosenstiel P, Franke A.  Improving mapping and SNP-calling performance in multiplexed targeted Next-Generation Sequencing.  BMC Genomics.  2012 Aug 22;13:417.

2150 ElSharawy A, Warner J, Olson J, Forster M, Schilhabel MB, Link DR, Rose-John S, Schreiber S, Rosenstiel P, Brayer J, Franke A. Accurate variant detection across non-amplified and whole genome amplified DNA using targeted next generation sequencing.   BMC Genomics. 2012 Sep 20;13:500.

2149 Emig D, Blankenburg H, Ramírez F, Albrecht M.  Functional characterization of human genes from exon expression and RNA interference results.  Methods Mol Biol. 2012;910:33-53.

2148 ENCODE Project Consortium (591 scientists) with Reinhardt R.  An integrated encyclopedia of DNA elements in the human genome. Nature. 2012 Sep 6;489(7414):57-74. doi: 10.1038/nature11247. PubMed PMID: 22955616.

2147 Endres K, Fahrenholz F.  Regulation of alpha-secretase ADAM10 expression and activity.  Exp Brain Res. 2012 Apr;217(3-4):343-52. Epub 2011 Oct 4.

2146 Endres K, Fahrenholz F.  The Role of the Anti-Amyloidogenic Secretase ADAM10 in Shedding the APP-like Proteins.  Curr Alzheimer Res. 2012 Feb 1;9(2):157-64.

2145 Engels H, Schüler HM, Zink AM, Wohlleber E, Brockschmidt A, Hoischen A, Drechsler M, Lee JA, Ludwig KU, Kubisch C, Schwanitz G, Weber RG, Leube B, Hennekam RC, Rudnik-Schöneborn S, Kreiß-Nachtsheim M, Reutter H. A phenotype map for 14q32.3 terminal deletions. Am J Med Genet A 158A(4):695-706.

2144 EPICURE Consortium, EMINet Consortium, Steffens M, Leu C, Ruppert AK, Zara F, Striano P, Robbiano A, Capovilla G, Tinuper P, Gambardella A, Bianchi A, La Neve A, Crichiutti G, de Kovel CG, Kasteleijn-Nolst Trenité D, de Haan GJ, Lindhout D, Gaus V, Schmitz B, Janz D, Weber YG, Becker F, Lerche H, Steinhoff BJ, Kleefuß-Lie AA, Kunz WS, Surges R, Elger CE, Muhle H, von Spiczak S, Ostertag P, Helbig I, Stephani U, Møller RS, Hjalgrim H, Dibbens LM, Bellows S, Oliver K, Mullen S, Scheffer IE, Berkovic SF, Everett KV, Gardiner MR, Marini C, Guerrini R, Lehesjoki AE, Siren A, Guipponi M, Malafosse A, Thomas P, Nabbout R, Baulac S, Leguern E, Guerrero R, Serratosa JM, Reif PS, Rosenow F, Mörzinger M, Feucht M, Zimprich F, Kapser C, Schankin CJ, Suls A, Smets K, De Jonghe P, Jordanova A, Caglayan H, Yapici Z, Yalcin DA, Baykan B, Bebek N, Ozbek U, Gieger C, Wichmann HE, Balschun T, Ellinghaus D, Franke A, Meesters C, Becker T, Wienker TF, Hempelmann A, Schulz H, Rüschendorf F, Leber M, Pauck SM, Trucks H, Toliat MR, Nürnberg P, Avanzini G, Koeleman BP, Sander T.  Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32.  Hum Mol Genet Hum Mol Genet. 2012 Dec 15;21(24):5359-72. doi: 10.1093/hmg/dds373.

2143 EPICURE Consortium, Leu C, de Kovel CG, Zara F, Striano P, Pezzella M, Robbiano A, Bianchi A, Bisulli F, Coppola A, Giallonardo AT, Beccaria F, Trenité DK, Lindhout D, Gaus V, Schmitz B, Janz D, Weber YG, Becker F, Lerche H, Kleefuss-Lie AA, Hallman K, Kunz WS, Elger CE, Muhle H, Stephani U, Møller RS, Hjalgrim H, Mullen S, Scheffer IE, Berkovic SF, Everett KV, Gardiner MR, Marini C, Guerrini R, Lehesjoki AE, Siren A, Nabbout R, Baulac S, Leguern E, Serratosa JM, Rosenow F, Feucht M, Unterberger I, Covanis A, Suls A, Weckhuysen S, Kaneva R, Caglayan H, Turkdogan D, Baykan B, Bebek N, Ozbek U, Hempelmann A, Schulz H, Rüschendorf F, Trucks H, Nürnberg P, Avanzini G, Koeleman BP, Sander T.  Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies.  Epilepsia. 2012 Feb;53(2):308-18.

2142 Erhard F, Lars Dölken, and Ralf Zimmer.  RIP-Chip enrichment analysis.  Bioinformatics, 29(1):77-83 (2013).

2141 Erhard, F. and R. Zimmer.  Detecting outlier peptides in quantitative high-throughput mass spectrometry data. Journal of Proteomics, 75(11):3230?3239, DOI:  10.1016/j.jprot.2012.03.032.

2140 Erkan M, Adler G, Apte MV, Bachem MG, Buchholz M, Detlefsen S, Esposito I, Friess H, Gress TM, Habisch HJ, Hwang RF, Jaster R, Kleeff J, Klöppel G, Kordes C, Logsdon CD, Masamune A, Michalski CW, Oh J, Phillips PA, Pinzani M, Reiser-Erkan C, Tsukamoto H, Wilson J.  StellaTUM: current consensus and discussion on pancreatic stellate cell research. Gut. 2012 Feb;61(2):172-8. doi: 10.1136/gutjnl-2011-301220. Epub 2011 Nov 24.

2139 Erkan M, Reiser-Erkan C, Michalski CW, Kong B, Esposito I, Friess H, Kleeff J. The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance. Curr Mol Med. 2012;12(3):288-303.

2138 Ersland KM, Christoforou A, Stansberg C, Espeseth T, Mattheisen M, Mattingsdal M, Hardarson GA, Hansen T, Fernandes CP, Giddaluru S, Breuer R, Strohmaier J, Djurovic S, Nöthen MM, Rietschel M, Lundervold AJ, Werge T, Cichon S, Andreassen OA, Reinvang I, Steen VM, LeHellard S.   Gene-based analysis of regionally enriched cortical genes in GWAS data sets of cognitive traits and psychiatric disorders.  PLoS ONE 7(2): e31687. doi:10.1371/journal.pone.0031687.

2137 Eschenburg Georg, Angelika Eggert, Alexander Schramm, Holger N. Lode, Patrick Hundsdoerfer Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-a independent apoptosis  Cancer Research2012 May 15;72(10):2645-56. doi: 10.1158/0008-5472.CAN-11-4072. Epub 2012 Apr 9.

2136 Etain B, Dumaine A, Bellivier F, Pagan C, Francelle L, Goubran-Botros H, Moreno S, Deshommes J, Moustafa K, Le Dudal K, Mathieu F, Henry C, Kahn JP, Launay JM, Mühleisen TW, Cichon S, Bourgeron T, Leboyer M, Jamain S.  Genetic and functional abnormalities of the melatonin biosynthesis pathway in patients with bipolar disorder.  Hum Mol Genet. 2012 Sep 15;21(18):4030-7. doi: 10.1093/hmg/dds227.

2135 Eulalio A, Schulte L, Vogel J  The mammalian microRNA response to bacterial infections RNA Biology 9(6):742-750

2134 Exner N, Lutz AK, Haass C, Winklhofer KF.  Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences.  EMBO J. 2012 Jun 26;31(14):3038-62.

2133 Eyerich S, Onken AT, Weidinger S, Franke A, Nasorri F, Pennino D, Grosber M, Pfab F, Schmidt-Weber CB, Mempel M, Hein R, Ring J, Cavani A, Eyerich K (2011)  Mutual antagonism of T cells causing psoriasis and atopic eczema.  New England journal of medicine 365(3): 231-8.

2132 Faria D, Schlicker A, Pesquita C, Bastos H, Ferreira AE, Albrecht M, Falcão AO.  Mining GO annotations for improving annotation consistency.  PLoS One. 2012;7(7):e40519..

2131 Farrall AL, Riemer P, Leushacke M, Sreekumar A, Grimm C, Herrmann BG, Morkel M.  Wnt and BMP signals control intestinal adenoma cell fates.  Int J Cancer. 2012 Feb 18. doi: 10.1002/ijc.27500.

2130 Fassl A., Tagscherer K., Richter J., Berriel Diaz M., Alcantara Llaguno S.R., Campos B., Herold-Mende C., Herzig S., Schmidt M.H.H., Parada L.F., Wiestler O.D., Roth W.  Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.  Oncogene 2012 Jan 16. doi: 10.1038/onc.2011.615. [Epub ahead of print]

2129 Fier H, Won S, Prokopenko D, AlChawa T, Ludwig KU, Fimmers R, Silverman EK, Pagano M, Mangold E, Lange C.  'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate.  Bioinformatics. 2012 Dec 1;28(23):3027-33. doi: 10.1093/bioinformatics/bts568.

2128  Filiou MD, Teplytska L, Otte DM, Zimmer A, Turck CW.  Myelination and oxidative stress alterations in the cerebellum of the G72/G30 transgenic schizophrenia mouse model.  J Psychiatr Res. 2012 Oct;46(10):1359-1365. doi: 10.1016/j.jpsychires.2012.07.004.

2127  Finan B, Yang B, Ottaway N, Stemmer K, Müller TD, Yi CX, Habegger K, Schriever SC, García-Cáceres C, Kabra DG, Hembree J, Holland J, Raver C, Seeley RJ, Hans W, Irmler M, Beckers J, Hrabé de Angelis M, Tiano JP, Mauvais-Jarvis F, Perez-Tilve D, Pfluger P, Zhang L, Gelfanov V, DiMarchi RD, Tschöp MH.  Targeted estrogen delivery reverses the metabolic syndrome.  Nat Med. 2012 Dec;18(12):1847-56. doi: 10.1038/nm.3009.

2126 Fischer A, Schmid B, Ellinghaus D, Nothnagel M, Gaede KI, Schürmann M, Lipinski S, Rosenstiel P, Zissel G, Höhne K, Petrek M, Kolek V, Pabst S, Grohé C, Grunewald J, Ronninger M, Eklund A, Padyukov L, Gieger C, Wichmann HE, Nebel A, Franke A, Müller-Quernheim J, Hofmann S, Schreiber S.  A novel sarcoidosis risk locus for Europeans on chromosome 11q13.1.   Am J Respir Crit Care Med. 2012 Nov 1;186(9):877-85.

2125 Fischer-Posovszky P, Tews D, Horenburg S, Debatin KM, Wabitsch M. Differential function of Akt1 and Akt2 in human adipocytes. Mol Cell Endocrinol. 2012 Jul 6;358(1):135-43

2124  Fitzgerald JC, Camprubi MD, Dunn L, Wu HC, Ip NY, Kruger R, Martins LM, Wood NW, Plun-
Favreau H. Phosphorylation of HtrA2 by cyclin dependent kinase 5 modulates its neuroprotective function.  Cell Death Differ 19: 257-266.

2123 Fleck D, Garratt AN, Haass C, Willem M. BACE1 dependent Neuregulin processing. Curr Alzheimer Res. 2012 Feb 1;9(2):178-83.

2122 Fletcher JI, Gherardi S, Murray J, Burkhart CA, Russell A, Valli E, Smith J, Oberthuer A, Ashton LJ, London WB, Marshall GM, Norris MD, Perini G, Haber M. N-Myc regulates expression of the detoxifying enzyme glutathione transferase GSTP1, a marker of poor outcome in neuroblastoma Cancer Res. 2012 Feb 15;72(4):845-53.

2121 Föcker M, Timmesfeld N, Scherag S, Knoll N, Singmann P, Wang-Sattler R, Bühren K, Schwarte R, Egberts K, Fleischhaker C, Adamski J, Illig T, Suhre K, Albayrak O, Hinney A, Herpertz-Dahlmann B, Hebebrand J.  Comparison of metabolic profiles of acutely ill and short-term weight recovered patients with anorexia nervosa reveals alterations of 33 out of 163 metabolites.  J Psychiatr Res. 2012 Dec;46(12):1600-9. doi: 10.1016/j.jpsychires.2012.08.015. Epub 2012 Sep 12. PubMed PMID: 22981704.

2120 Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE, Bergquist A, Ryu E, Ponsioen CY, Runz H, Sterneck M, Vermeire S, Beuers U, Wijmenga C, Schrumpf E, Manns MP, Lazaridis KN, Schreiber S, Baines JF, Franke A, Karlsen TH.  Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci.  J Hepatol. 2012 Aug;57(2):366-75. doi: 0.1016/j.jhep.2012.03.031. Epub 2012 Apr 18. PMID: 22521342.

2119 Franceschini N, van Rooij FJ, Prins BP, Feitosa MF, Karakas M, Eckfeldt JH, Folsom AR, Kopp J, Vaez A, Andrews JS, Baumert J, Boraska V, Broer L, Hayward C, Ngwa JS, Okada Y, Polasek O, Westra HJ, Wang YA, Del Greco M F, Glazer NL, Kapur K, Kema IP, Lopez LM, Schillert A, Smith AV, Winkler CA, Zgaga L; LifeLines Cohort Study, Bandinelli S, Bergmann S, Boban M, Bochud M, Chen YD, Davies G, Dehghan A, Ding J, Doering A, Durda JP, Ferrucci L, Franco OH, Franke L, Gunjaca G, Hofman A, Hsu FC, Kolcic I, Kraja A, Kubo M, Lackner KJ, Launer L, Loehr LR, Li G, Meisinger C, Nakamura Y, Schwienbacher C, Starr JM, Takahashi A, Torlak V, Uitterlinden AG, Vitart V, Waldenberger M, Wild PS, Kirin M, Zeller T, Zemunik T, Zhang Q, Ziegler A, Blankenberg S, Boerwinkle E, Borecki IB, Campbell H, Deary IJ, Frayling TM, Gieger C, Harris TB, Hicks AA, Koenig W, O' Donnell CJ, Fox CS, Pramstaller PP, Psaty BM, Reiner AP, Rotter JI, Rudan I, Snieder H, Tanaka T, van Duijn CM, Vollenweider P, Waeber G, Wilson JF, Witteman JC, Wolffenbuttel BH, Wright AF, Wu Q, Liu Y, Jenny NS, North KE, Felix JF, Alizadeh BZ, Cupples LA, Perry JR, Morris AP. Discovery and fine mapping of serum protein loci through transethnic meta-analysis. Am J Hum Genet. 2012 Oct 5;91(4):744-53.

2118 Frank J, Cichon S, Treutlein J, Ridinger M, Mattheisen M, Hoffmann P, Herms S, Wodarz N, Soyka M, Zill P, Maier W, Mössner R, Gaebel W, Dahmen N, Scherbaum N, Schmäl C, Steffens M, Lucae S, Ising M, Müller-Myhsok B, Nöthen MM, Mann K, Kiefer F, Rietschel M.  Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.  Addict Biol. 2012 Jan;17(1):171-80. doi: 10.1111/j.1369-1600.2011.00395.

2117 Fransen K, Mitrovic M, van Diemen CC, Thelma BK, Sood A, Franke A, Schreiber S, Midha V, Juyal G, Potocnik U, Fu J, Nolte I, Weersma RK. Limited evidence for parent-of-origin effects in inflammatory bowel disease associated loci.<http://www.ncbi.nlm.nih.gov/pubmed/23028907> PLoS One. 2012;7(9):e45287. doi: 10.1371/journal.pone.0045287. Epub 2012 Sep 27.

2116 Frasa MA, Koessmeier KT, Ahmadian MR, Braga VM.  Illuminating the functional and structural repertoire of human TBC/RABGAPs.  Nat Rev Mol Cell Biol 13:67-73. PMID: 22251903

2115 Fredebohm J, Boettcher M, Eisen C, Gaida MM, Heller A, Keleg S, Tost J, Greulich-Bode KM, Hotz-Wagenblatt A, Lathrop M, Giese NA, Hoheisel JD.   Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system.   PLoS One 2012; 7:e48503.

2114 Freilinger T, Anttila V, de Vries B, Malik R, Kallela M, Terwindt GM, Pozo-Rosich P, Winsvold B, Nyholt DR, van Oosterhout WP, Artto V, Todt U, Hämäläinen E, Fernández-Morales J, Louter MA, Kaunisto MA, Schoenen J, Raitakari O, Lehtimäki T, Vila-Pueyo M, Göbel H, Wichmann E, Sintas C, Uitterlinden AG, Hofman A, Rivadeneira F, Heinze A, Tronvik E, van Duijn CM, Kaprio J, Cormand B, Wessman M, Frants RR, Meitinger T, Müller-Myhsok B, Zwart JA, Färkkilä M, Macaya A, Ferrari MD, Kubisch C, Palotie A, Dichgans M, van den Maagdenberg AM; International Headache Genetics Consortium.  Genome-wide association analysis identifies susceptibility loci for migraine without aura.  Nat Genet. 2012; 44(7):777-82.

2113 Freitag CM, Asherson P, Hebebrand J.  Behavioural genetics of childhood disorders.  Curr Top Behav Neurosci. 2012;12:395-428. doi: 10.1007/7854_2011_178. PubMed PMID: 22382729.

2112 Fritsch C, Herrmann A, Nothnagel M, Szafranski K, Huse K, Schumann F, Schreiber S, Platzer M, Krawczak M, Hampe J, Brosch M.   Genome-wide search for novel human uORFs and N-terminal protein extensions using ribosomal footprinting. Genome Res. 2012 Nov;22(11):2208-18.

2111 Fröhlich KS, Papenfort K, Berger AA, Vogel J  A conserved RpoS-dependent small RNA controls the synthesis of major porin OmpD Nucleic Acids Research 40(8):3623-40

2110 Frohn A., Eberl H.C., Stöhr J., Glasmacher E., Rüdel S., Heismeyer V., Mann M. & Meister G.  Dicer-dependent and -independent Argonaute2 protein interaction networks in mammalian cells.  Molecular and Cellular proteomics, 11(11):1442-56.

2109 Frommolt P, Abdallah AT, Altmüller J, Motameny S, Becker C, Stemshorn K, Fischer M, Freilinger T, Nürnberg P. Assessing the enrichment performance in targeted resequencing experiments.  Hum Mutat, 2012, 33(4): 635-641.

2108 Frost A, Marc G. Elgort, Onn Brandman, Clinton Ives, Sean R. Collins, Lakshmi Miller-Vedam, Jimena Weibezahn, Marco Y. Hein, Ina Poser, Matthias Mann, Anthony A. Hyman and Jonathan S. Weissman.  Comparing Genetic Interactions between S. pombe and S. cerevisiaeReveals Functional Repurposing and Identifies New Determinants ofOrganelle Homeostasis and Mitotic Transitions.  Cell. 2012;149(6):1339-52. doi:10.1016/j.cell.2012.04.028.

2107 Fuchs H, Gailus-Durner V, Neschen S, Adler T, Afonso L, Aguilar-Pimentel JA, Becker L, Bohla A, Calzada-Wack J, Cohrs C, Dewert A, Fridrich B, Garrett L, Glasl L, Götz A, Hans W, Hölter SM, Horsch M, Hurt A, Janas E, Janik D, Kahle M, Kistler M, Klein-Rodewald T, Lengger C, Ludwig T, Maier H, Marschall S, Micklich K, Möller G, Naton B, Prehn C, Puk O, Rácz I, Räß M, Rathkolb B, Rozman J, Scheerer M, Schiller E, Schrewe A, Steinkamp R,  Stöger C, Sun M, Szymczak W, Treise I, Vargas Panesso IL, Vernaleken AM, Willershäuser M, Wolff-Muscate A, Zeh R, Adamski J, Beckers J, Bekeredjian R, Busch DH, Eickelberg O, Favor J, Graw J, Höfler H, Höschen C, Katus H, Klingenspor M, Klopstock T, Neff F, Ollert M, Schulz H, Stöger T, Wolf E, Wurst W, Yildirim AÖ, Zimmer A, Hrabé de Angelis M:  Innovations in phenotyping of mouse models in the German Mouse Clinic.  Mamm Genome. 2012 Oct;23(9-10):611-22. doi: 10.1007/s00335-012-9415-1.

2106 Fuchs H, Sabrautzki S, Seedorf H, Rathkolb B, Rozman J, Hans W, Schneider R, Klaften M, Hölter SM, Becker L, Klempt M, Elvert R, Wurst W, Klopstock T, Klingenspor M, Wolf E, Gailus-Durner V, Hrabé de Angelis M:  Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines.  Eur J Oral Sci. 120, 269-77 (2012). DOI: 10.1111/j.1600-0722.2012.00966.

2105 Fusco S, Ripoli C, Podda MV, Ranieri SC, Leone L, Toietta G, McBurney MW, Schütz G, Riccio A, Grassi C, Galeotti T, Pani G.  A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restriction.  Proc Natl Acad Sci USA. 2012; 109:621-626. E-pub 2011.

2104 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Calogero RA, Couchman JR, Lund AH:  Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone  PLoS Genet. 8(5), e1002711 (2012) doi:10.1371/journal.pgen.1002711.

2103 Ganea K, Menke A, Schmidt MV, Lucae S, Rammes G, Liebl C, Harbich D, Sterlemann V, Storch C, Uhr M, Holsboer F, Binder EB, Sillaber I, Müller MB.  Convergent animal and human evidence suggests the activin/inhibin pathway to be involved in antidepressant response.  Transl Psychiatry. 2012 Oct 23;2:e177.

2102 Garai Á, Zeke A, Gógl G, Tör? I, Förd?s F, Blankenburg H, Bárkai T, Varga J, Alexa A, Emig D, Albrecht M, Reményi A.  Specificity of linear motifs that bind to a common mitogen-activated protein kinase docking groove.  Sci Signal. 2012 Oct 9;5(245):ra74.

2101 Garcia I, Mayol G, Ríos J, Domenech G, Cheung NK, Oberthuer A, Fischer M, Maris JM, Brodeur GM, Hero B, Rodríguez E, Suñol M, Galvan P, de Torres C, Mora J, Lavarino C. A Three-Gene Expression Signature Model for Risk Stratification of Patients with Neuroblastoma. Clin Cancer Res. 2012 Apr 1;18(7):2012-2023.

2100 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C.  Impact of dopamineversus serotonin cell transplantation for the development of graft-induceddyskinesia in a rat Parkinson model.  Brain Res. 2012 Aug 27;1470:119-29. doi:10.1016/j.brainres.2012.06.029.

2099 Garrett L, Lie DC, Hrabé de Angelis M, Wurst W, Hölter SM:  Voluntary wheel running in mice increases the rate of neurogenesis without affecting anxiety-related behaviour in single tests.  BMC Neurosci. 2012 Jun 8;13(1):61. http://www.biomedcentral.com/1471-2202/13/61.

2098 Gärtner J, Wolf J, Voltz R. Early palliative care for patients with metastatic cancer. Curr Opin Oncol 2012;24:357-362 

2097 Gerdes S, Osadtschy S, Rostami-Yazdi M, Buhles N, Weichenthal M, Mrowietz U (2012)  Leptin, adiponectin, visfatin and retinol-binding protein-4 - mediators of comorbidities in patients with psoriasis?  Exp Dermatol 21(1): 43-7.

2096 Getlik, M., C. Grütter, J.R. Simard, H.D. Nguyen, A. Robubi, B. Aust, W.A. van Otterlo* and D. Rauh. Structure-based design, synthesis and biological evaluation of N-pyrazole, N'-thiazole urea inhibitors of MAP kinase p38? Eur J Med Chem, 2012, 48:1-15.

2095 Getlik, M., J.R. Simard, M. Termathe, C. Grütter, M. Rabiller, W.A.L. van Otterlo, D. Rauh. Fluorophore labeled kinase detects ligands that bind within the MAPK insert of p38?Kinase PLoS ONE, 2012, 7(7):e39713.

2094 Ghezzi D, Baruffini E, Haack TB, Invernizzi F, Melchionda L, Dallabona C, Strom TM, Parini R, Burlina AB, Meitinger T, Prokisch H, Ferrero I, Zeviani M. Mutations of the mitochondrial-tRNA modifier MTO1 cause hypertrophic cardiomyopathy and lactic acidosis. Am J Hum Genet. 2012 Jun 8;90(6):1079-87

2093 Giehl KA, Eckstein GN, Pasternack SM, Praetzel-Wunder S, Ruzicka T, Lichtner P, Seidl K, Rogers M, Graf E, Langbein L, Braun-Falco M, Betz RC, Strom TM. Nonsense mutations in AAGAB cause punctate palmoplantar keratoderma type Buschke-Fischer-Brauer. Am J Hum Genet. 2012 Oct 5;91(4):754-9.

2092 Gispert S, Kurz A, Waibel S, Bauer P, Liepelt I, Geisen C, Gitler AD, Becker T, Weber M, Schulte C,  Berg D, Andersen PM, Krüger R, Riess O, Ludolph AC, Auburger G. The modulation of Amyotrophic Lateral Sclerosis risk by Ataxin-2 intermediate polyglutamine expansions is a specific effect.  Neurobiol Dis 45: 356-61.

2091 Gladwin TE, Derks EM; Genetic Risk and Outcome of Psychosis (GROUP), Rietschel M, Mattheisen M, Breuer R, Schulze TG, Nöthen MM, Levinson D, Shi J, Gejman PV, Cichon S, Ophoff RA.  Segment-wise genome-wide association analysis identifies a candidate region associated with schizophrenia in three independent samples.  PLoS One. 2012;7(6):e38828. doi: 10.1371/journal.pone.0038828.

2090 Glas J, Seiderer J, Czamara D, Pasciuto G, Diegelmann J, Wetzke M, Olszak T, Wolf C, Müller-Myhsok B, Balschun T, Achkar JP, Kamboh MI, Franke A, Duerr RH, Brand S. PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-?B and XBP1 binding sites.<http://www.ncbi.nlm.nih.gov/pubmed/23300802> PLoS One. 2012;7(12):e52873. doi: 10.1371/journal.pone.0052873. Epub 2012 Dec 27.

2089 Glasl L, Kloos K, Giesert F, Roethig A, Di Benedetto B, Kühn R, Zhang J, Hafen U, Zerle J, Hofmann A, Hrabé de Angelis M, Winklhofer KF, Hölter SM, Vogt Weisenhorn DM, Wurst W.(2012)  Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb.  Exp Neurol. 2012 Jan 11. doi:10.1016/j.expneurol.2012.01.002.

2088 Godoy P, Cadenas C, Hellwig B, Marchan R, Stewart J, Reif R, Lohr M, Gehrmann M, Rahnenführer J, Schmidt M, Hengstler JG.  Interferon-inducible guanylatebinding protein (GBP2) is associated with better prognosis in breast cancer andindicates an efficient T cell response.  Breast Cancer. 2012 Sep 22. [Epub ahead of print] 

2087 Goek ON, Döring A, Gieger C, Heier M, Koenig W, Prehn C, Römisch-Margl W, Wang-Sattler R, Illig T, Suhre K, Sekula P, Zhai G, Adamski J, Köttgen A, Meisinger C. Serum metabolite concentrations and decreased GFR in the general population. Am J Kidney Dis 2012;60:197-206.

2086 Goes, F. S., Hamshere, M. L., Seifuddin, F., Pirooznia, M., Belmonte-Mahon, P., Breuer, R., Schulze, T., et al.  Genome-wide association of mood-incongruent psychotic bipolar disorder.  Transl psychiatry, 2012, 2, e180. doi:10.1038/tp.2012.106.

2085 Graf C, Kuehne C, Panhuysen M, Puetz B, Weber P, Holsboer F, Wurst W, Deussing JM.  Corticotropin-releasing hormone regulates common target genes with divergent functions in corticotrope and neuronal cells.  Mol Cell Endocrinol. 2012 Oct 15;362(1-2):29-38.

2084 Granada M, Wilk JB, Tuzova M, Strachan DP, Weidinger S, Albrecht E, Gieger C, Heinrich J, Himes BE, Hunninghake GM, Celedón JC, Weiss ST, Cruikshank WW, Farrer LA, Center DM, O'Connor GT. A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. J Allergy Clin Immunol 2012; 129:840-845.

2083 Gravel S et al. (2012).  Demographic history and rare allele sharing among human populations.  Proc Natl Acad Sci U S A. 108(29):11983-8.

2082 Gregor A, Albrecht B, Bader I, Bijlsma EK, Ekici AB, Engels H, Hackmann K, Horn D, Hoyer J, Klapecki J, Kohlhase J, Maystadt I, Nagl S, Prott E, Tinschert S, Ullmann R, Wohlleber E, Woods G, Reis A, Rauch A, Zweier C. Expanding the clinical spectrum associated with defects in CNTNAP2 and NRXN1.  BMC Med Genet. 2011, 12:106. doi: 10.1186/1471-2350-12-106.

2081 Greif PA, Konstandin NP, Metzeler KH, Herold T, Pasalic Z, Ksienzyk B, Dufour A, Schneider F, Schneider S, Kakadia PM, Braess J, Sauerland MC, Berdel WE, Büchner T, Woermann BJ, Hiddemann W, Spiekermann K, Bohlander SK.  RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes.  Haematologica. 2012;97:1909-1915.

2080 Greif PA., Dufour, A., Konstandin, N.P., Ksienzyk, B., Zellmeier, E., Tizazu, B., Sturm, J., Benthaus, T., Herold, T., Yaghmaie, M., Dörge, P., Hopfner, K.P., Hauser, A., Graf, A., Krebs, S., Blum, H., Kakadia, P.M., Schneider, S., Hoster, E., Schneider, F., Stanulla, M., Braess, J., Sauerland, M.C., Berdel, W.E., Büchner, T., Woermann, B.J., Hiddemann, W., Spiekermann, K., Bohlander, S.K.  GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.  Blood. 2012, 120:395-403.

2079 Greliche N, Zeller T, Wild PS, Rotival M, Schillert A, Ziegler A, Deloukas P, Erdmann J, Hengstenberg C, Ouwehand WH, Samani NJ, Schunkert H, Munzel T, Lackner KJ, Cambien F, Goodall AH, Tiret L, Blankenberg S, Trégouët DA; Cardiogenics Consortium. Comprehensive exploration of the effects of miRNA SNPs on monocyte gene expression. Plos One. 2012;7(9):e45863.

2078 Gress TM, Kestler HA, Lausser L, Fiedler L, Sipos B, Michalski CW, Werner J, Giese N, Scarpa A, and Buchholz M.  Differentiation of multiple types of pancreatico-biliary tumors by molecular analysis of clinical specimens.  J Mol Med., 90: 457-464. 

2077 Gries M, Davies L, Liu Y, Bachhuber A, Spiegel J, Dillmann U, Hartmann T, Fassbender K, Walter S.  Response of Toll-like receptors in experimental Guillain-Barré syndrome: A kinetic analysis. Neurosci Lett. 2012 Jun 19;518(2):154-60.

2076 Grimm MO, Zinser EG, Grosgen S, Hundsdorfer B, Rothhaar TL, Burg VK, Kaestner L, Bayer TA, Lipp P, Muller U, Grimm HS, Hartmann T. Amyloid Precursor Protein (APP) Mediated Regulation of Ganglioside Homeostasis Linking Alzheimer's Disease Pathology with Ganglioside Metabolism.  PLoS One 7:e34095.

2075 Grüner BM, Hahne H, Mazur PK, Trajkovic-Arsic M, Maier S, Esposito I, Kalideris E, Michalski CW, Kleeff J, Rauser S, Schmid RM, Küster B, Walch A, Siveke JT.  MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer.  PLoS ONE 2012; 7(6):e39424. doi: 10.1371/journal.pone.0039424.

2074 Grünewald A, Arns B, Seibler P, Rakovic A, Münchau A, Ramirez A, Sue CM, Klein C.  ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome.  Neurobiol Aging 2012.

2073 Grunewald T. G. P., A. Ranft, I. Esposito, P. da Silva-Buttkus, M. Aichler, D. Baumhoer, K. L. Schaefer, L. Ottaviano, C. Poremba, G. Jundt, H. Jürgens, U. Dirksen, G. H. S. Richter and S. Burdach. High STEAP1 expression is associated with improved outcome of Ewing's sarcoma patients.  Annals of Oncology, Volume 23, Issue 8. Pp. 2185-2190.

2072 Grütter, C., J.R. Simard, S.C. Mayer-Wrangowski, P.H. Schreier, J. Pérez-Martín, A. Richters, M. Getlik, O. Gutbrod, C.A. Braun, M.E. Beck, D. Rauh. Targeting GSK3 from Ustilago maydis: Type-II kinase Inhibitors as Potential Antifungals ACS. Chem Biol, 2012, 7(7):1257-67

2071 Guan K, Cheng IF, Baazm M.  Human spermatagonial stem cells: a novel therapeutic hope for cardiac regeneration and repair? . Future Cardiol. 2012;8(1):39-51.

2070 Guan M, Marschall S, Raspa M, Pickard AR, Fray MD (2012)  Overview of new developments in and the future of cryopreservation in the laboratory mouse.  Mamm Genome. 23(9-10):572-9. doi: 10.1007/s00335-012-9423-1.

2069 Guo W, Schafer S, Greaser ML, Radke MH, Liss M, Govindarajan T, Maatz H,Schulz H, Li S, Parrish AM, Dauksaite V, Vakeel P, Klaassen S, Gerull B,Thierfelder L, Regitz-Zagrosek V, Hacker TA, Saupe KW, Dec GW, Ellinor PT, Macrae CA, Spallek B, Fischer R, Perrot A, Ozcelik C, Saar K, Hubner N, Gotthardt M.  RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.  Nat Med. [Epub ahead of print] PubMed PMID: 2466703.

2068 Haack TB, Hogarth P, Kruer MC, Gregory A, Wieland T, Schwarzmayr T, Graf E, Sanford L, Meyer E, Kara E, Cuno SM, Harik SI, Dandu VH, Nardocci N, Zorzi G, Dunaway T, Tarnopolsky M, Skinner S, Frucht S, Hanspal E, Schrander-Stumpel C, Héron D, Mignot C, Garavaglia B, Bhatia K, Hardy J, Strom TM, Boddaert N, Houlden HH, Kurian MA, Meitinger T, Prokisch H, Hayflick SJ. Exome sequencing reveals de novo WDR45 mutations causing a phenotypically distinct, X-linked dominant form of NBIA. Am J Hum Genet. 2012 Dec 7;91(6):1144-9.

2067 Haag D, Zipper P, Westrich V, Karra D, Pfleger K, Toedt G, Blond F, Delhomme N, Hahn M, Reifenberger J, Reifenberger G, Lichter P.  Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration.  PLoS Genet. 2012;8(3):e1002572.

2066 Habermann K. and B.M.H. Lange. New insights into subcomplex assembly and modifications of centrosomal proteins.  Cell Div. 2012 Jul 16;7(1):17. doi: 10.1186/1747-1028-7-17.

2065 Hackmann K, Matko S, Gerlach EM, von der Hagen M, Klink B, Schrock E, Rump A, Di Donato N.  Partial deletion of GLRB and GRIA2 in a patient with intellectual disability.  Eur J Hum Genet. 2013 Jan;21(1):112-4. doi: 10.1038/ejhg.2012.97. Epub 2012 Jun 6.

2064 Haenisch B, Herms S, Mattheisen M, Steffens M, Breuer R, Strohmaier J, Degenhardt F, Schmäl C, Lucae S, Maier W, Rietschel M, Nöthen MM, Cichon S.  Genome-wide association data provide further support for an association between 5-HTTLPR and major depressive disorder.  J Affect Disord. 2013 Apr 25;146(3):438-40. doi: 10.1016/j.jad.2012.08.001.

2063 Hammer C, Cichon S, Mühleisen TW, Haenisch B, Degenhardt F, Mattheisen M, Breuer R, Witt SH, Strohmaier J, Oruc L, Rivas F, Babadjanova G, Grigoroiu-Serbanescu M, Hauser J, Röth R, Rappold G, Rietschel M, Nöthen MM, Niesler B.  Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study.  Transl Psychiatry. 2012 Apr 17;2:e103. doi: 10.1038/tp.2012.30.

2062 Hamshere ML, Walters JT, Smith R, Richards AL, Green E, Grozeva D, Jones I, Forty L, Jones L, Gordon-Smith K, Riley B, O'Neill T, Kendler KS, Sklar P, Purcell S, Kranz J; The Schizophrenia Psychiatric Genome-wide Association Study Consortium (PGC): Schizophrenia Psychiatric Genome-Wide Association Study Consortium: St Clair D, Cichon S, Rietschel M, Nöthen MM, Maier W, Schulze TG, Mattheisen M, Kirov GK, O'Donovan MC, Holmans PA, Georgieva L, Nikolov I, Williams HJ, Toncheva D, Milanova V, Owen MJ, O'Donovan MC, Craddock N, Holmans PA, Hamshere M, Williams HJ, Moskvina V, Dwyer S, Georgieva L, Zammit S, Owen MJ, Kirov GK, Sullivan PF, Lin DY, van den Oord E, Kim Y, Stroup T, Lieberman JA, Hansen T, Ingason A, Olsen L, Schmock H, Skjødt C, Thygesen JH, Rosengren A, Werge T, Morris DW, O'Dushlaine CT, Kenny E, Quinn EM, Gill M, Corvin A, Blackwood DH, McGhee KA, Pickard B, Malloy P, Maclean AW, McIntosh A, Gejman PV, Sanders AR, Duan J, Levinson DF, Shi J, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, Cloninger C, Giegling I, Hartmann AM, Konnerth H, Friedl M, Konte B, Muglia P, Rujescu D, Pato MT, Pato CN, Fanous A, Hultman CM, Lichtenstein P, Bergen SE, Purcell S, Scolnick E, Sklar P, Sullivan PF, Djurovic S, Mattingsdal M, Agartz I, Melle I, Andreassen OA, Ophoff RA, Cantor RM, Freimer NB, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I, Strengman E, McQuillin A, Choudhury K, Datta S, Pimm J, Thirumalai S, Puri V, Krasucki R, Lawrence J, Quested D, Bass N, Gurling H, Malhotra AK, Lencz T., Wellcome Trust Case Control Consortium+ (WTCCC+), Wellcome Trust Case Control Consortium 2 (WTCCC2), Morris D, Gill M, Holmans P, Craddock N, Corvin A, Owen MJ, O'Donovan MC.  Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.  Mol Psychiatry. 2012 May 22. doi: 10.1038/mp.2012.67.

2061 Hartz SM, Short SE, Saccone NL, Culverhouse R, Chen L, Schwantes-An TH, Coon H, Han Y, Stephens SH, Sun J, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Geller F, Gubjartsson D, Hansel NN, Jiang C, Keskitalo-Vuokko K, Liu Z, Lyytikainen LP, Michel M, Rawal R, Rosenberger A, Scheet P, Shaffer JR, Teumer A, Thompson JR, Vink JM, Vogelzangs N, Wenzlaff AS, Wheeler W, Xiao X, Yang BZ, Aggen SH, Balmforth AJ, Baumeister SE, Beaty T, Bennett S, Bergen AW, Boyd HA, Broms U, Campbell H, Chatterjee N, Chen J, Cheng YC, Cichon S, Couper D, Cucca F, Dick DM, Foroud T, Furberg H, Giegling I, Gu F, Hall AS, Hallfors J, Han S, Hartmann AM, Hayward C, Heikkila K, Hewitt JK, Hottenga JJ, Jensen MK, Jousilahti P, Kaakinen M, Kittner SJ, Konte B, Korhonen T, Landi MT, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Muley T, Murray T, Nauck M, North K, Pergadia M, Polasek O, Ramos EM, Ripatti S, Risch A, Ruczinski I, Rudan I, Salomaa V, Schlessinger D, Styrkarsdottir U, Terracciano A, Uda M, Willemsen G, Wu X, Abecasis G, Barnes K, Bickeboller H, Boerwinkle E, Boomsma DI, Caporaso N, Duan J, Edenberg HJ, Francks C, Gejman PV, Gelernter J, Grabe HJ, Hops H, Jarvelin MR, Viikari J, Kahonen M, Kendler KS, Lehtimaki T, Levinson DF, Marazita ML, Marchini J, Melbye M, Mitchell BD, Murray JC, Nothen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Sanders AR, Schwartz AG, Shete S, Shi J, Spitz M, Stefansson K, Swan GE, Thorgeirsson T, Volzke H, Wei Q, Wichmann HE, Amos CI, Breslau N, Cannon DS, Ehringer M, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Stitzel JA, Weiss RB, Kraft P, Bierut LJ  Increased Genetic Vulnerability to Smoking at CHRNA5 in Early-Onset Smokers.  Arch Gen Psychiatry 69:854-60.

2060 Hashimoto T, Perlot T, Rehman A, Trichereau J, Ishiguro H, Paolino M, Sigl V, Hanada T, Hanada R, Lipinski S, Wild B, Camargo SM, Singer D, Richter A, Kuba K, Fukamizu A, Schreiber S, Clevers H, Verrey F, Rosenstiel P*, Penninger JM.  ACE2links amino acid malnutrition to microbial ecology and intestinal inflammation. Nature. 2012 Jul 25;487(7408):477-81. doi: 10.1038/nature11228. PubMed PMID:22837003.

2059 Häsler R, Feng Z, Bäckdahl L, Spehlmann ME, Franke A, Teschendorff A, RakyanVK, Down TA, Wilson GA, Feber A, Beck S, Schreiber S, Rosenstiel P.  A functional methylome map of ulcerative colitis Genome Res. 2012 Nov;22(11):2130-7. doi:10.1101/gr.138347.112. Epub 2012 Jul 23. PubMed PMID: 22826509; PubMed CentralPMCID: PMC3483542.

2058 Haß J, Walton E, Kirsten H, Liu J, Priebe L, Wolf C, Karbalai N, Gollub R, White T, Rößner V,  Scholz M, Cichon S, Calhoun V, Ehrlich S.  A genome-wide association study suggests novel loci associated with a schizophrenia-related brain-based phenotype.  PLoS One. 2013 Jun 21;8(6):e64872. Print 2013.

2057 Hau P, Jachimczak P, Schlaier J, Bogdahn U.  TGF-ß2 signaling in high-gradegliomas.  Curr Pharm Biotechnol. 2011 Dec;12(12):2150-7. Review. PubMed PMID: 21619538.

2056 Haupt A, G. Joberty, M. Bantscheff, H. Fröhlich, H. Stehr, M. R. Schweiger, A. Fischer, M. Kerick, S.T. Boerno, A. Dahl, M. Lappe, H. Lehrach, C. Gonzalez, G. Drewes and B.M.H. Lange. Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics. BMC Cancer. 2012 Jan 25;12:38. doi: 10.1186/1471-2407-12-38.

2055 Haupt A, Joberty G, Bantscheff M, Frohlich H, Stehr H, Schweiger MR, Fischer A, Kerick M, Boerno ST, Dahl A, Lappe M, Lehrach H, Gonzalez C, Drewes G, Lange BM. Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics. BMC Cancer. 2012 Jan 25;12(1):38

2054 Håvik B, Degenhardt FA, Johansson S, Fernandes CP, Hinney A, Scherag A, Lybæk H, Djurovic S, Christoforou A, Ersland KM, Giddaluru S, O'Donovan MC, Owen MJ, Craddock N, Mühleisen TW,Mattheisen M, Schimmelmann BG, Renner T, Warnke A, Herpertz-Dahlmann B, Sinzig J, Albayrak Ö, Rietschel M, Nöthen MM, Bramham CR, Werge T, Hebebrand J, Haavik J, Andreassen OA, Cichon S, Steen VM, Le Hellard S.  DCLK1 variants are associated across schizophrenia and attention deficit/hyperactivity disorder.  PLoS One. 2012;7(4):e35424. doi: 10.1371/journal.pone.0035424.

2053 Hebebrand J, Albayrak Ö. Leptin treatment of patients with anorexia nervosa?The urgent need for initiation of clinical studies.  Eur Child Adolesc Psychiatry.2012 Feb;21(2):63-6. PubMed PMID: 22290117.

2052 Hebebrand J.  OBESITY FACTS - a Success Story.  Obes Facts. 2012;5(1):151-153. Epub 2012 Mar 2. PubMed PMID: 22433626. 

2051 Hegele A, Kamburov A, Grossmann A, Sourlis C, Wowro S, Weimann M, Will CL, Pena V, Lührmann R, Stelzl U.  Dynamic protein-protein interaction wiring of the human spliceosome.  Mol Cell. 2012 Feb 24;45(4):567-80.

2050 Helbig KL, Nothnagel M, Hampe J, Balschun T, Nikolaus S, Schreiber S, Franke A, Nöthlings U.  A case-only study of gene-environment interaction between genetic susceptibility variants in NOD2 and cigarette smoking in Crohn's disease aetiology.  BMC Med Genet. 2012 Mar 14;13:14.

2049 Henjes F, Bender C, von der Heyde S, Braun L, Mannsperger HA, Schmidt C, Wiemann S, Hasmann M, Aulmann S, Beissbarth T et al: Strong EGFR signaling in cell line models of ERBB2-amplified breast cancer attenuates response towards ERBB2-targeting drugs.  Oncogenesis 2012, 1(7):e16.

2048 Henrich KO, Schwab M, Westermann F. 1p36 tumor suppression--a matter ofdosage?  Cancer Res. 2012 Dec 1;72(23):6079-88. doi:10.1158/0008-5472.CAN-12-2230. Epub 2012 Nov 20. Review. PubMed PMID: 23172308.

2047 Herder C, Peeters W, Illig T, Baumert J, de Kleijn DP, Moll FL, Poschen U, Klopp N, Muller-Nurasyid M, Roden M, Preuss M, Karakas M, Meisinger C, Thorand B, Pasterkamp G, Koenig W, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, Konig IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies. PLoS One 2012; 6: e25734. doi: 10.1371/journal.pone.0025734PONE-D-11-10980 [pii]

2046 Hermann D, Weber-Fahr W, Sartorius A, Hoerst M, Frischknecht U, Tunc-Skarka N, Perreau-Lenz S, Hansson AC, Krumm B, Kiefer F, Spanagel R, Mann K, Ende G, Sommer WH. Translational Magnetic Resonance Spectroscopy Reveals Excessive Central  Glutamate Levels During Alcohol Withdrawal in Humans and Rats.  Biol Psychiatry, 2012 Jun 1;71(11):1015-21. doi: 10.1016/j.biopsych.2011.07.034.

2045 Herold T, Mulaw MA, Jurinovic V, Seiler T, Metzeler KH, Dufour A, Schneider S, Kakadia PM, Spiekermann K, Mansmann U, Hiddemann W, Buske C, Dreyling M, Bohlander SK. High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature. Leuk Lymphoma. 2012 Dec 27. [Epub ahead of print]

2044 Heuckmann JM, Balke-Want H, Malchers F, Peifer M, Sos ML, Koker M, Meder L, Lovly CM, Heukamp LC, Pao W, Küppers R, Thomas RK.  Differential protein stability and ALK inhibitor sensitivity of EML4-ALK fusion variants.  Clin Cancer Res. 2012 Sep 1;18(17):4682-90. doi: 10.1158/1078-0432.CCR-11-3260. Epub 2012 Aug 21.

2043 Hilger M and Matthias Mann:  Triple SILAC to determine stimulus specific interactions in the Wnt pathway.  J Proteome Res. 2012; 11(2):982-94. Epub 2011 Nov 18. doi:10.1021/pr200740a.

2042 Hochrath K, Krawczyk M, Goebel R, Langhirt M, Rathkolb B, Micklich K, Rozman J, Horsch M, Beckers J, Klingenspor M, Fuchs H, Gailus-Durner V, Wolf E, Acalovschi M, Volmer DA, Hrab? de Angelis M, Lammert F. The hepatic phosphatidylcholine transporter ABCB4 as modulator of glucose homeostasis.  FASEB J. 2012 Dec;26(12):5081-91. doi: 10.1096/fj.12-209379.

2041 Hofmann S, Fischer A, Nothnagel M, Jacobs G, Schmid B, Wittig M, Franke A, Gaede KI, Schürmann M, Petrek M, Mrazek F, Pabst S, Grohé C, Grunewald J, Ronninger M, Eklund A, Rosenstiel P, Höhne K, Zissel G, Müller-Quernheim J, Schreiber S. Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. Eur Respir J. 2012 Aug 30.

2040 Hoheisel, J.D. Antikörper zur Funktions-Analyse des Proteoms. Laborwelt 3, 16-17. 

2039 Holmans P, Moskvina V, Jones L, Sharma M, The International Parkinson's Disease Genomics Consortium (IPDGC), Vedernikov A, Büchel F, Sadd M, Bras JM, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Gibbs JR, Schulte C, Durr A, Guerreiro R, Hernandez D, Brice A, Stefánsson H, Majamaa K, Gasser T, Heutink P, Wood NW, Martinez M, Singleton, AB, Nalls MA, Hardy J, Morris HR, and Williams NM.  A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease.  Human Molecular Genetics, December 2012. doi: 10.1093/hmg/dds492.

2038 Holthoewer D, Endres K, Schuck F, Hiemke C, Schmitt U, Fahrenholz F.  Acitretin, an enhancer of alpha-secretase expression, crosses the blood-brain barrier and is not eliminated by P-glycoprotein.  Neurodegener Dis. 2012;10(1-4):224-8.

2037 Hooli BV, Mohapatra G, Mattheisen, M, Parrado AR, Roehr JT,Shen YP, Gusella J, Moir R, Saunders AJ, Lange C, Tanzi RE, Bertram L. The role of common and rare APP DNA sequence variants in Alzheimer's disease. Neurology 2012 17;78(16):1250-7.

2036 Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos M, Thomas R, Lowery D, Fischer M, Roels F, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Medema R, Yaffe MB, Schermer B, Reinhardt HC, Benzing T. AATF/Che1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.  EMBO J, 2012, 31(20): 3961-3975.

2035 Hoyer, J., Ekici, A. B., Endele, S., Popp, B., Zweier, C., Wiesenerl, A., Wohlleber, E., Dufke, A., Petsch, C., Zweier, M., Göhring, I., Zink, A. M., Rappold, G., Schröck, E., Wieczorek, D., Rieß, O., Engels, H., Rauch, A., Reis, A. Haploinsufficiency of ARID1B, a member of the SWI/SNF A chromatin remodeling complex, is a frequent cause of intellectual disability. Am J of Human Genetics,  90:565-572, 2012.

2034 Huang J et al. (2012)  1000 Genomes-based imputation identifies novel and refined associations for the Wellcome Trust Case Control Consortium phase 1 Data.  Eur J Hum Genet.: EJHG (January):1-5.

2033 Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin SY, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD, Smith NL, Williams SM, Ikram MA, Kleber ME, Becker DM, Truong V, Mychaleckyj JC, Tang W, Yang Q, Sennblad B, Moore JH, Williams FM, Dehghan A, Silbernagel G, Schrijvers EM, Smith S, Karakas M, Tofler GH, Silveira A, Navis GJ, Lohman K, Chen MH, Peters A, Goel A, Hopewell JC, Chambers JC, Saleheen D, Lundmark P, Psaty BM, Strawbridge RJ, Boehm BO, Carter AM, Meisinger C, Peden JF, Bis JC, McKnight B, Öhrvik J, Taylor K, Franzosi MG, Seedorf U, Collins R, Franco-Cereceda A, Syvänen AC, Goodall AH, Yanek LR, Cushman M, Müller-Nurasyid M, Folsom AR, Basu S, Matijevic N, van Gilst WH, Kooner JS, Hofman A, Danesh J, Clarke R, Meigs JB; DIAGRAM Consortium, Kathiresan S, Reilly MP; CARDIoGRAM Consortium, Klopp N, Harris TB, Winkelmann BR, Grant PJ, Hillege HL, Watkins H; C4D Consortium, Spector TD, Becker LC, Tracy RP, März W, Uitterlinden AG, Eriksson P, Cambien F; CARDIOGENICS Consortium, Morange PE, Koenig W, Soranzo N, van der Harst P, Liu Y, O'Donnell CJ, Hamsten A. Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood 2012;120:4873-4881.

2032 Huang L, Jolly LA, Willis-Owen S, Gardner A, Kumar R, Douglas E, Shoubridge C, Wieczorek D, Tzschach A, Cohen M, Hackett A, Field M, Froyen G, Hu H, Haas SA, Ropers HH, Kalscheuer VM, Corbett MA, Gecz J.  A noncoding, regulatory mutation implicates HCFC1 in nonsyndromic intellectual disabilty.  Am J Hum Genet 2012, 91: 694-702.

2031 Hughes MF, Saarela O, Stritzke J, Kee F, Silander K, Klopp N, Kontto J, Karvanen J, Willenborg C, Salomaa V, Virtamo J, Amouyel P, Arveiler D, Ferrières J, Wiklund PG, Baumert J, Thorand B, Diemert P, Trégouët DA, Hengstenberg C, Peters A, Evans A, Koenig W, Erdmann J, Samani NJ, Kuulasmaa K, Schunkert H. Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts. PLoS One. 2012;7(7):e40922. doi: 10.1371/journal.pone.0040922. Epub 2012 Jul 25.

2030 Huhn S, Bevier M, Rudolph A, Pardini B, Naccarati A, Hein R, Hoffmeister M, Vodickova L, Novotny J, Brenner H, Chang-Claude J, Vodicka P, Hemminki K, Försti A.  Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.  BMC Med Genet 2012;13:94. doi: 10.1186/1471-2350-13-94.

2029 Huhn S, Pardini B, Naccarati A, Vodicka P, Hemminki K, Försti A.  Ancestral susceptibility to colorectal cancer.  Mutagenesis 2012:27(2)197-204. doi: 10.1093/mutage/ger061.

2028 Hussain MS, Baig SM, Neumann S, Nürnberg G, Farooq M, Ahmad I, Alef T, Hennies HC, Technau M, Altmüller J, Frommolt P, Thiele H, Noegel AA, Nürnberg P.  A truncating mutation of CEP135 causes primary microcephaly and disturbed centrosomal function.  Am J Hum Genet. 2012 May 4;90(5):871-8. doi: 10.1016/j.ajhg.2012.03.016. Epub 2012 Apr 19.

2027 Hüttemann M, Lee I, Gao X, Pecina P, Pecinova A, Liu J, Aras S, Sommer N, Sanderson TH, Tost M, Neff F, Aguilar-Pimentel JA, Becker L, Naton B, Rathkolb B, Rozman J, Favor J, Hans W, Prehn C, Puk O, Schrewe A, Sun M, Höfler H, Adamski J, Bekeredjian R, Graw J, Adler T, Busch DH, Klingenspor M, Klopstock T, Ollert M, Wolf E, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Weissmann N, Doan JW, Bassett DJ, Grossman LI.:  Cytochrome c oxidase subunit 4 isoform 2 knockout mice show reduced enzyme activity, airway hyporeactivity, and lung pathology  FASEB Journal, 2012 Sep;26(9):3916-30. doi: 10.1096/fj.11-203273.

2026 Ichimura A, Hirasawa A, Poulain-Godefroy O, Bonnefond A, Hara T, Yengo L, Kimura I, Leloire A, Liu N, Iida K, Choquet H, Besnard P, Lecoeur C, Vivequin S, Ayukawa K, Takeuchi M, Ozawa K, Tauber M, Maffeis C, Morandi A, Buzzetti R, Elliott P, Pouta A, Jarvelin MR, Körner A, Kiess W, Pigeyre M, Caiazzo R, Van Hul W, Van Gaal L, Horber F, Balkau B, Lévy-Marchal C, Rouskas K, Kouvatsi A, Hebebrand J, Hinney A, Scherag A, Pattou F, Meyre D, Koshimizu TA, Wolowczuk I, Tsujimoto G, Froguel P.  Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human.  Nature. 2012 Feb 19;483(7389):350-4. doi: 10.1038/nature10798. PMID: 22343897 [PubMed - in process] 

2025 IL6R Genetics Consortium Emerging Risk Factors Collaboration, Sarwar N, Butterworth AS, Freitag DF, Gregson J, Willeit P, Gorman DN, Gao P, Saleheen D, Rendon A, Nelson CP, Braund PS, Hall AS, Chasman DI, Tybjærg-Hansen A, Chambers JC, Benjamin EJ, Franks PW, Clarke R, Wilde AA, Trip MD, Steri M, Witteman JC, Qi L, van der Schoot CE, de Faire U, Erdmann J, Stringham HM, Koenig W, Rader DJ, Melzer D, Reich D, Psaty BM, Kleber ME, Panagiotakos DB, Willeit J, Wennberg P, Woodward M, Adamovic S, Rimm EB, Meade TW, Gillum RF, Shaffer JA, Hofman A, Onat A, Sundström J, Wassertheil-Smoller S, Mellström D, Gallacher J, Cushman M, Tracy RP, Kauhanen J, Karlsson M, Salonen JT, Wilhelmsen L, Amouyel P, Cantin B, Best LG, Ben-Shlomo Y, Manson JE, Davey-Smith G, de Bakker PI, O'Donnell CJ, Wilson JF, Wilson AG, Assimes TL, Jansson JO, Ohlsson C, Tivesten Å, Ljunggren Ö, Reilly MP, Hamsten A, Ingelsson E, Cambien F, Hung J, Thomas GN, Boehnke M, Schunkert H, Asselbergs FW, Kastelein JJ, Gudnason V, Salomaa V, Harris TB, Kooner JS, Allin KH, Nordestgaard BG, Hopewell JC, Goodall AH, Ridker PM, Hólm H, Watkins H, Ouwehand WH, Samani NJ, Kaptoge S, Di Angelantonio E, Harari O, Danesh J.  Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet 2012;379:1205-1213.

2024 Irmler M, Gentier RJ, Dennissen FJ, Schulz H, Bolle I, Hölter SM, Kallnik M, Cheng JJ, Klingenspor M, Rozman J, Ehrhardt N, Hermes DJ, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Meyer HE, Hopkins DA, Van Leeuwen FW, Beckers J:  Long-term proteasomal inhibition in transgenic mice by UBB+1 expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients  Acta Neuropathologica. 124, 187-97 (2012). doi:10.1007/s00401-012-1003-7.

2023 Ivandic BT, Mastitsky SE, Schönsiegel F, Bekeredjian R, Eils R, Frey N, Katus HA, Brors B.  Whole-genome analysis of gene expression associates the ubiquitin-proteasome system with the cardiomyopathy phenotype in disease-sensitized congenic mouse strains. Cardiovasc Res. 2012 Apr 1;94(1):87-95.

2022 Jing, L., Haas, J., Chong, T.M., Bruckner, J.J., Dann, G.C., Dong, L.,Marshak, J.O.,  McClurkan, C.L., Yamamoto, T.N., Bailer, S.M., Laing, K.J., Wald, A., Verjans, G.M.G.M. and Koelle, D.M. Cross-presentation and genome-wide screening reveal candidate T cells antigens for a herpes simplex virus type 1 vaccine J Clin Invest. 2012 Feb 1;122(2):654-73. doi: 10.1172/JCI60556. Epub 2012 Jan 3.

2021 JJang MH, Kitabatake Y, Kang E, Jun H, Pletnikov MV, Christian KM, Hen R, Lucae S, Binder EB, Song H, Ming GI.  Secreted frizzled-related protein 3 (sFRP3) regulates antidepressant responses in mice and humans.  Mol Psychiatry. 2012 Dec 4. doi: 10.1038/mp.2012.158. [Epub ahead of print]

2020 Jones DT, Jager N, Kool M, Zichner T, Hutter B, Sultan M, Cho YJ, Pugh TJ, Hovestadt V, Stutz AM et al:  Dissecting the genomic complexity underlying medulloblastoma.  Nature 2012, 488(7409):100-105.

2019 Jostins L et al.  Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.  Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582.

2018 Jürgensen C, Brand J, Nothnagel M, Arlt A, Neser F, Habeck JO, Schreiber S, Stölzel U, Zeitz M, Hampe J.  Prognostic relevance of gastric cancer staging by endoscopic ultrasound.  Surg Endosc. 2012 Oct 6.

2017 Jurmeister S, Baumann M, Balwierz A, Keklikoglou I, Ward A, Uhlmann S, Zhang JD, Wiemann S, Sahin O (2012)  MicroRNA-200c Represses Migration and Invasion of Breast Cancer Cells by Targeting Actin-Regulatory Proteins FHOD1 and PPM1F.  Mol Cell Biol 32: 633-651.

2016 Kabesch M, Adcock IM.  Epigenetics in asthma and COPD.  Biochimie. 2012Nov;94(11):2231-41. doi: 10.1016/j.biochi.2012.07.017. Epub 2012 Jul 31. Review. PubMed PMID: 22874820.

2015 Kahraman D, Holstein A, Scheffler M, Zander T, Nogova L, Lammertsma AA, Boellaard R, Neumaier B, Dietlein M, Wolf J, Kobe C. Tumor lesion glycolysis and tumor lesion proliferation for response prediction and prognostic differentiation in patients with advanced non-small cell lung cancer treated with erlotinib.  Clin Nucl Med 2012;37:1058-1064

2014 Kamburov A, Grossmann A, Herwig R, Stelzl U.  Cluster-based assessment ofprotein-protein interaction confidence.  BMC Bioinformatics. 2012 Oct 10;13:262.doi: 10.1186/1471-2105-13-262.

2013 Kamburov A, Stelzl U, Herwig R.  IntScore: a web tool for confidence scoring ofbiological interactions.  Nucleic Acids Res. 2012 Jul;40(Web Server issue):W140-6. doi: 10.1093/nar/gks492.

2012 Kam-Thong, T., C. A. Azencott, L. Cayton, B. Putz, A. Altmann, N. Karbalai, P. G. Samann, B. Scholkopf, B. Muller-Myhsok, and K. M. Borgwardt.  GLIDE: GPU-based linear regression for detection of epistasis.  Hum Hered 2012;73:220?236, DOI:10.1159/000341885.

2011 Kappelmann M., Kuphal S., Meister G., Varidom L. & Bosserhoff A.K. MicroRNA miR-125b controls melanoma progression by direct regulation of c-Jun protein expression.  Oncogene, in press. doi: 10.1038/onc.2012.307.

2010 Karakas M, Baumert J, Kleber ME, Thorand B, Dallmeier D, Silbernagel G, Grammer TB, Rottbauer W, Meisinger C, Illig T, März W, Koenig W. A variant in the Abo gene explains the variation in soluble E-selectin levels-results from dense genotyping in two independent populations. PLoS One 2012;7:e51441.

2009 Kariv-Inbal Z, Yacobson S, Berkecz R, Peter M, Janaky T, Lutjohann D, Broersen LM, Hartmann T, Michaelson DM.  The Isoform-Specific Pathological Effects of ApoE4 in vivo are Prevented by a Fish Oil (DHA) Diet and are Modified by Cholesterol.  J Alzheimers Dis. 2012;28(3):667-83.

2008 Karlsson RM, Adermark L, Molander A, Perreau-Lenz S, Singley E, Solomon M, Holmes A, Tanaka K, Lovinger DM, Spanagel R, Heilig M. Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST.  Neuropharmacology. 2012 Aug;63(2):181-9.

2007 Keers R, Pedroso I, Breen G, Aitchison KJ, Nolan PM, Cichon S, Nöthen MM, Rietschel M, Schalkwyk LC, Fernandes C.  Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours.  PLoS One. 2012;7(6):e38263. doi: 10.1371/journal.pone.0038263.

2006 Kees T, Lohr J, Noack J, Mora R, Gdynia G, Tödt G, Ernst A, Radlwimmer B, Falk CS, Herold-Mende C, Régnier-Vigouroux A.  Microglia isolated from patients with glioma gain antitumor activities on poly (I:C) stimulation.  Neuro Oncol. 2012 Jan;14(1):64-78. Epub 2011 Oct 20.

2005 Keklikoglou I, Koerner C, Schmidt C, Zhang JD, Heckmann D, Shavinskaya A, Allgayer H, Guckel B, Fehm T, Schneeweiss A, Sahin O, Wiemann S, Tschulena U (2012)  MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kappaB and TGF-beta signaling pathways.  Oncogene 2012, 31(37):4150-4163.

2004 Keller A et al.  New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing.  Nat Commun. 2012 Feb 28;3:698. doi: 10.1038/ncomms1701.

2003 Keller MC, Simonson MA, Ripke S, Neale BM, Gejman PV, Howrigan DP, Lee SH, Lencz T, Levinson DF, Sullivan PF Runs of homozygosity implicate autozygosity as a schizophrenia risk factor.  PLoS Genet. 2012;8(4):e1002656. doi: 10.1371/journal.pgen.1002656.

2002 Keller MF, Saad M, Bras J, Bettella F, Nicolaou N, Simón-Sánchez J, Mittag F, Büchel F, Sharma M, Gibbs JR, Schulte C, Moskvina V, Durr A, Holmans P, Kilarski LL, Guerreiro R, Hernandez DG, Brice A, Ylikotila P, Stefánsson H, Majamaa K, Morris HR, Williams N, Gasser T, Heutink P, Wood NW, Hardy J, Martinez M, Singleton AB, Nalls MA; International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2).  Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease.  Hum Mol Genet. 2012 Nov 15;21(22):4996-5009. doi: 10.1093/hmg/dds335..

2001 Keßler M, Just S, Rottbauer W.  Ion flux dependent and independent functions of ion channels in the vertebrate heart: lessons learned from zebrafish.  Stem Cells Int. 2012;2012:462161.

2000 Khayrullina GA, Raabe CA, Hoe CH, Becker K, Reinhardt R, Tang TH, Rozhdestvensky TS, Kopylov AM. Transcription Analysis and Small Non-Protein Coding RNAs Associated with Bacterial Ribosomal Protein Operons. Curr Med Chem. 2012 Oct 1;19(30):5187-98. PubMed PMID: 22680642.

1999 Khuong-Quang DA, Buczkowicz P, Rakopoulos P, Liu XY, Fontebasso AM, Bouffet E, Bartels U, Albrecht S, Schwartzentruber J, Letourneau L, Bourgey M, Bourque G, Montpetit A, Bourret G, Lepage P, Fleming A, Lichter P, Kool M, von Deimling A, Sturm D, Korshunov A, Faury D, Jones DT, Majewski J, Pfister SM, Jabado N, Hawkins C.  K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas.  Acta Neuropathol. 2012 Sep;124(3):439-47.

1998 Kleffmann, W.; Zink, A.M., Lee, J.A.; Senderek, J.; Mangold, E.; Moog, U.; Rappold, G.A.; Wohlleber, E.; Engels, H.  5q31 Microdeletions: Definition of a Critical Region and Analysis of LRRTM2, a Candidate Gene for Intellectual Disability Molecular Syndromology 3:68-75.

1997 Klinkenberg M, Gispert S, Dominguez-Bautista JA, Braun I, Auburger G, Jendrach M. Restriction of trophic factors and nutrients induces PARKIN expression. Neurogenetics. 2012 Feb;13(1):9-21.

1996 Klionski D, ?, Burbulla LF, ?,  Krüger R, ?, Zuckerbraun B (1269 authors listed). Guidelines for the use and interpretation of assays for monitoring autophagy.  Autophagy  8: 445-544.

1995 Kloiber S, Czamara D, Karbalai N, Müller-Myhsok B, Hennings J, Holsboer F, Lucae S. ANK3 and CACNA1C--missing genetic link for bipolar disorder and major depressive disorder in two German case-control samples. J Psychiatr Res. 2012 Aug;46(8):973-9. doi: 10.1016/j.jpsychires.2012.04.017. Epub 2012 May 29

1994 Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, Uhr M, Dose T, Unschuld PG, Zihl J, Binder E, Müller-Myhsok B, Holsboer F, Lucae S.  Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels.  Eur Neuropsychopharmacol. 2012 Sep 28. doi:pii: S0924-977X(12)00228-3. 10.1016/j.euroneuro.2012.08.010. [Epub ahead of print]

1993 Klymiuk I, Kenner L, Adler T, Busch DH, Boersma A, Irmler M, Gailus-Durner V, Fuchs H, Leitner N, Müller M, Kühn R, Schlederer M, Treise I, de Angelis MH, Beckers J. (2012):  In vivo functional requirement of the mouse Ifitm1 gene for germ cell development, interferon mediated immune response and somitogenesis.  PLoS One 7(10):e44609. doi: 10.1371/journal.pone.0044609.

1992 Knoll N, Volckmar AL, Pütter C, Scherag A, Kleber M, Hebebrand J, Hinney A, Reinehr T.  The fatty acid amide hydrolase (FAAH) gene variant rs324420 AA/AC is not associated with weight loss in a 1-year lifestyle intervention for obese children and adolescents. 8. Horm Metab Res. 2012 Jan;44(1):75-7. doi: 10.1055/s-0031-1291306. Epub 2011 Nov

1991 Knuppel S, Esparza-Gordillo J, Marenholz I, Holzhutter H, Bauerfeind A, Ruether A, Weidinger S, Lee YA, Rohde K.  Multi-locus stepwise regression: a haplotype-based algorithm for finding genetic associations applied to atopic dermatitis.  BMC Med Genet 2012; 27;13:8.

1990 Kobe C, Scheffler M, Holstein A, Zander T, Nogova L, Lammertsma AA, Boellaard R, Neumaier B, Ullrich RT, Dietlein M, Wolf J, Kahraman D. Predictive value of early and late residual 18f-fluorodeoxyglucose and 18f-fluorothymidine uptake using different suv measurements in patients with non-small-cell lung cancer treated with erlotinib.  Eur J Nucl Med Mol Imaging 2012;39:1117-1127.

1989 Koch, A., H.B. Rode, A. Richters, D. Rauh, S. Hauf. A chemical genetic approach for covalent inhibition of analogue-sensitive aurora kinase ACS Chem Biol, 2012, 7(4):723-31.

1988 Koeberle, S.C., S. Fischer, D. Schollmeyer, V. Schattel, C. Grütter, D. Rauh, S. A. Laufer. Design, Synthesis, and Biological Evaluation of Novel Disubstituted Dibenzosuberones as Highly Potent and Selective Inhibitors of p38 Mitogen Activated Protein Kinase J Med Chem, 2012, 55(12):5868-77.

1987 Kollmus H, Post R, Brielmeier M, Fernandez J, Fuchs H, McKerlie C, Montoliu L, Otaegui PJ, Rebelo M, Riedesel H, Ruberte J, Sedla?ek R, Hrabé de Angelis M, Schughart K:  Structural and functional concepts employed in current mouse phenotyping and archiving facilities.  JAALAS. 51, 418-435 (2012) PMID: 23043807.

1986 Korshunov A, Remke M, Kool M, Hielscher T, Northcott PA, Williamson D, Pfaff E, Witt H, Jones DT, Ryzhova M, Cho YJ, Wittmann A, Benner A, Weiss WA, von Deimling A, Scheurlen W, Kulozik AE, Clifford SC, Peter Collins V, Westermann F, Taylor MD, Lichter P, Pfister SM. Biological and clinical heterogeneity of MYCN-amplified medulloblastoma. Acta Neuropathol. 2012 Apr;123(4):515-27.

1985 Kowarik MC, Einhäuser J, Jochim B, Büttner A, Tölle TR, Riemenschneider M, Platzer S, Berthele A.  Impact of the COMT Val(108/158)Met polymorphism on the mu-opioid receptor system in the human brain: Mu-opioid receptor, met-enkephalin and beta-endorphin expression.  Neurosci Lett. 2012;506(2):214-9.

1984 Kowarz E, Dingermann T, Marschalek R Do Non-Genomically Encoded Fusion Transcripts Cause Recurrent Chromosomal Translocations?  Cancers 4, 1036-1049.

1983 Kreck Benjamin et al. (2012).  B-SOLANA: an approach for the analysis of two-base encoding bisulfite sequencing data.  Bioinformatics 28(3): 428-9.

1982 Krentz S, Hof J, Mendioroz A, Vaggopoulou R, Dörge P, Lottaz C, Engelmann JC, Groeneveld TWL, Körner G, Seeger K, Hagemeier C, Henze G, Eckert C, von Stackelberg A, Kirschner-Schwabe R.  Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia.  Leukemia. 2013 Feb;27(2):295-304. doi: 10.1038/leu.2012.155. Epub 2012 Jun 13.

1981 Kroenlein H, Schwartz S, Reinhardt R, Rieder H, Molkentin M, Gökbuget N, Hoelzer D, Thiel E, Burmeister T.  Molecular analysis of the t(2;8)/MYC-IGK translocation in high-grade lymphoma/leukemia by long-distance inverse PCR. Genes Chromosomes Cancer. 2012 Mar;51(3):290-9. doi: 10.1002/gcc.21915. Epub 2011 Nov 25. PubMed PMID: 22120970.

1980 Kröger C, Dillon SC, Cameron AD, Papenfort K, Sivasankaran SK, Hokamp K, Chao Y, Sittka A, Hebrard M, Händler K, Colgan A, Leekitcharoenphon P, Langridge GC, Lohan AJ, Loftus B, Lucchini S, Ussery DW, Dorman CJ, Thomson NR, Vogel J, Hinton JC  The transcriptional landscape and small RNAs of Salmonella enterica serovar Typhimurium PNAS 109(20):E1277-86

1979 Krohn A, Diedler T, Burkhardt L, Mayer PS, De Silva C, Meyer-Kornblum M, Kötschau D, Tennstedt P, Huang J, Gerhäuser C, Mader M, Kurtz S, Sirma H, Saad F, Steuber T, Graefen M, Plass C, Sauter G, Simon R, Minner S, Schlomm T.  Genomic deletion of PTEN is associated with tumor progression and early PSA recurrence in ERG fusion positive and fusion negative prostate cancer.  Am J Pathol. 2012 Aug;181(2):401-12. doi: 10.1016/j.ajpath.2012.04.026. Epub 2012 Jun 13.

1978 Krueger F et al. (2012).  DNA methylome analysis using short bisulfite sequencing data.  Nat Methods 9(2):145-51.

1977 Kuehnen P, Mischke M, Wiegand S, Sers C, Horsthemke B, Grueters A, Krude H (2012)  An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity. PLoS Genetics, 8: e1002543

1976 Kuhn, P.-H., Koroniak, K., Hogl, S., Colombo, A., Zeitschel, U., Willem, M., Volbracht, C., Schepers, U., Imhof, A., Hoffmeister, A., Haass, C., Rossner, S., Bräse, S. and Lichtenthaler, S.F. Secretome Protein Enrichment with Click Sugars Identifies Physiological Substrates of the Alzheimer Protease BACE1 in Primary Neurons. EMBO J. 2012 Jun 22;31(14):3157-68.

1975 Kühne C, Puk O, Graw J, Hrab? de Angelis M, Schütz G, Wurst W, Deussing JM.  Visualizing corticotropin-releasing hormone receptor type 1 expression and neuronal connectivities in the mouse using a novel multifunctional allele.  J Comp Neurol. 2012 Oct 1;520(14):3150-80. doi: 10.1002/cne.23082.

1974 Kumar KR, Lohmann K, Klein C.  Genetics of Parkinson disease and other movement disorders.  Curr Opin Neurol 2012;25:466-474.

1973 Kumar S, Rathkolb B, Budde BS, Nürnberg P, Hrab? de Angelis M, Aigner B, Schneider MR. Gsdma3(I359N) is a novel ENU-induced mutant mouse line for studying the function of Gasdermin A3 in the hair follicle and epidermis.  J Dermatol Sci. 2012 Sep;67(3):190-2. doi: 10.1016/j.jdermsci.2012.05.001.

1972 Kuner R, Brase JC, Sültmann H, Wuttig D Gade S.  miRNA biomarkers in body fluids of prostate cancer patients.  Methods. 2013 Jan;59(1):132-7. doi: 10.1016/j.ymeth.2012.05.004. Epub 2012 May 29.

1971 Künkele A, De Preter K, Heukamp L, Thor T, Pajtler KW, Hartmann W, Mittelbronn M, Grotzer MA, Deubzer HE, Speleman F, Schramm A, Eggert A, Schulte JH.  Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.  Neuro Oncol. 2012 Jul;14(7):859-69. doi: 10.1093/neuonc/nos115. Epub 2012 May 16.

1970 Kurz A, May C, Schmidt O, Müller T, Stephan C, Meyer HE, Gispert S, Auburger G, Marcus K. A53T-alpha-synuclein-overexpression in the mouse nigrostriatal pathway leads to early increase of 14-3-3 epsilon and late increase of GFAP. J Neural Transm. 2012 Mar;119(3):297-312.

1969 Laczny C., Petra Leidinger, Jan Haas, Nicole Ludwig, Christina Backes, Andreas Gerasch, Michael Kaufmann, Britta Vogel, Hugo A. Katus, Benjamin Meder, Cord Stahler, Eckart Meese, Hans-Peter Lenhof and Andreas Keller.  miRTrail--a comprehensive webserver for analyzing gene and miRNA patterns to enhance the understanding of regulatory mechanisms in diseases. BMC Bioinformatics 2012,13:56 (epub ahead)

1968 Lammich S, Kamp F, Wagner J, Nuscher B, Zilow S, Ludwig AK, Willem M, Haass C J.  Translational repression of the Disintegrin and Metalloprotease ADAM10 by stable G-quadruplex Secondary structure in its 5`Untranslated region.  J Biol Chem. 2011 Dec 30;286(52):45063-72. Epub 2011 Nov 7.

1967 Lascorz J, Bevier M, Schönfels WV, Kalthoff H, Aselmann H, Beckmann J, Egberts J, Buch S, Becker T, Schreiber S, Hampe J, Hemminki K, Försti A, Schafmayer C.  Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer. BMC Med Genet 2012;13:31. doi: 10.1186/1471-2350-13-31.

1966 Laucht M, Blomeyer D, Buchmann AF, Treutlein J, Schmidt MH, Esser G, Jennen-Steinmetz C, Rietschel M, Zimmermann US, Banaschewski T.  Catechol-O-methyltransferase Val158 Met genotype, parenting practices and adolescent alcohol use: testing the differential susceptibility hypothesis.  J Child Psychol Psychiatry. 2012 Apr;53(4):351-9. doi: 10.1111/j.1469-7610.2011.02408.

1965 Lausser L, Müssel C, Melkozerov A, Kestler HA.  Identifying predictive hubs to condense the training set of k-nearest neighbour classifiers.  Computational Statistics. 2012.  

1964 Lee AW, Hengstler H, Schwald K, Berriel-Diaz M, Loreth D, Kirsch M, Kretz O, Haas CA, Hrabé de Angelis M, Herzig S, Brümmendorf T, Klingenspor M, Rathjen FG, Rozman J, Nicholson G, Cox RD, Schäfer MK.  Functional inactivation of the genome-wide association study obesity gene neuronal growth regulator 1 in mice causes a body mass phenotype.  PLoS ONE. 7(7), e41537 (2012) doi: 10.1371/journal.pone.0041537.

1963 Lee SH, DeCandia T, Ripke S, Yang J, The Schizophrenia Psychiatric Genome Wide Association Study Consortium (PGC-SCZ) Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L, Visscher PM, Posthuma D, Ruderfer DM, Fanous A, Stefansson H, Steinberg S, Mowry BJ, Golimbet V, De Hert M, Jönsson EG, Bitter I, Pietiläinen OP, Collier DA, Tosato S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bergen SE, Black DW, Børglum AD, Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger CR, Cormican P, Craddock N, Danoy PA, Datta S, de Haan L, Demontis D, Dikeos D, Djurovic S, Donnelly P, Donohoe G, Duong L, Dwyer S, Fink-Jensen A, Freedman R, Freimer NB, Friedl M, Georgieva L, Giegling I, Gill M, Glenthøj B, Godard S, Hamshere M, Hansen M, Hansen T, Hartmann AM, Henskens FA, Hougaard DM, Hultman CM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jürgens G, Kahn RS, Keller MC, Kenis G, Kenny E, Kim Y, Kirov GK, Konnerth H, Konte B, Krabbendam L, Krasucki R, Lasseter VK, Laurent C, Lawrence J, Lencz T, Lerer FB, Liang KY, Lichtenstein P, Lieberman JA, Linszen DH, Lönnqvist J, Loughland CM, Maclean AW, Maher BS, Maier W, Mallet J, Malloy P, Mattheisen M, Mattingsdal M, McGhee KA, McGrath JJ, McIntosh A, McLean DE, McQuillin A, Melle I, Michie PT, Milanova V, Morris DW, Mors O, Mortensen PB, Moskvina V, Muglia P, Myin-Germeys I, Nertney DA, Nestadt G, Nielsen J, Nikolov I, Nordentoft M, Norton N, Nöthen MM, O'Dushlaine CT, Olincy A, Olsen L, O'Neill FA, Orntoft TF, Owen MJ, Pantelis C, Papadimitriou G, Pato MT, Peltonen L, Petursson H, Pickard B, Pimm J, Pulver AE, Puri V, Quested D, Quinn EM, Rasmussen HB, Réthelyi JM, Ribble R, Rietschel M, Riley BP, Ruggeri M, Schall U, Schulze TG, Schwab SG, Scott RJ, Shi J, Sigurdsson E, Silverman JM, Spencer CC, Stefansson K, Strange A, Strengman E, Stroup TS, Suvisaari J, Terenius L, Thirumalai S, Thygesen JH, Timm S, Toncheva D, van den Oord E, van Os J, van Winkel R, Veldink J, Walsh D, Wang AG, Wiersma D, Wildenauer DB, Williams HJ, Williams NM, Wormley B, Zammit S, Sullivan PF, O'Donovan MC, Daly MJ, Gejman PV,The International Schizophrenia Consortium (ISC), The Molecular Genetics of Schizophrenia Collaboration (MGS), Sullivan PF, Goddard ME, Keller MC, Visscher PM,  Wray NR.  Estimating the proportion of variation in susceptibility to schizophrenia captured by common SNPs.  Nat Genet. 2012 Feb 19;44(3):247-50. doi: 10.1038/ng.1108.

1962 Leischner H, Albers C, Grundler R, Razumovskaya E, Spiekermann K, Bohlander S, Rönnstrand L, Götze K, Peschel C, Duyster J.  SRC is a signaling mediator in FLT3-ITD but not in FLT3-TKD positive AML.  Blood. 2012 Apr 26;119(17):4026-33. doi: 10.1182/blood-2011-07-365726. Epub 2012 Mar 12.

1961 Lennertz L, Wagner M, Wölwer W, Schuhmacher A, Frommann I, Berning J, Schulze-Rauschenbach S, Landsberg MW, Steinbrecher A, Alexander M, Franke PE, Pukrop R, Ruhrmann S, Bechdolf A, Gaebel W, Klosterkötter J, Häfner H, Maier W, Mössner R. A promoter variant of SHANK1 affects auditory working memory in schizophrenia patients and in subjects clinically at risk for psychosis. Eur Arch Psychiatry Clin Neurosci. 2012 Mar;262(2):117-24.

1960 Leuner K, Schütt T, Kurz C, Eckert SH, Schiller C, Occhipinti A, Mai S, Jendrach M, Eckert GP, Kruse SE, Palmiter RD, Brandt U, Dröse S, Wittig I, Willem M, Haass C, Reichert AS, Mueller WE.  Mitochondria-deriived ROS lead to enhanced amyloid beta formation.  Antioxid Redox Signal. 2012 Jan 9.

1959 Li J, Pandey V, Kessler T, Lehrach H, and Wierling C.  Modeling of miRNA and Drug Action in the EGFR-Signaling Pathway  PLoS ONE. 2012; 7(1):e30140. doi:10.1371/journal.pone.0030140.

1958 Li M, Wang Y, Zheng XB, Ikeda M, Iwata N, Luo XJ, Chong SA, Lee J, Rietschel M, Zhang F, Müller-Myhsok B, Cichon S, Weinberger DR, Mattheisen M, Schulze TG, Martin NG, Mitchell PB, Schofield PR, Liu JJ, Su B; MooDS Consortium. Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility. Schizophr Res. 2012 Dec;142(1-3):200-5. doi: 10.1016/j.schres.2012.10.008.

1957 Li Z., Ender C., Meister G., Moore P.S., Chang Y. & John B.  Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs.  Nucleic Acids Research, 40(14):6787-99.

1956 Lipinski S, Grabe N, Jacobs G, Billmann-Born S, Till A, Häsler R, Aden K,Paulsen M, Arlt A, Kraemer L, Hagemann N, Erdmann KS, Schreiber S, Rosenstiel P.  RNAi screening identifies mediators of NOD2 signaling: implications for spatialspecificity of MDP recognition.  Proc Natl Acad Sci U S A. 2012 Dec26;109(52):21426-31. doi: 10.1073/pnas.1209673109. Epub 2012 Dec 3. PubMed PMID: 23213202; PubMed Central PMCID: PMC3535590.

1955 Lisauskas T, Matula P, Claas C, Reusing S, Wiemann S, Erfle H, Lehmann L, Fischer P, Eils R, Rohr K et al:  Live-cell assays to identify regulators of ER-to-Golgi trafficking.  Traffic 2012, 13(3):416-432.

1954 Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, Rube CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K.  TLR2 Is a Primary Receptor for Alzheimer?s Amyloid beta Peptide To Trigger Neuroinflammatory Activation. J Immunol. 2012 Feb 1;188(3):1098-107.

1953 Longoni M, Lage K, Russell MK, Loscertales M, Abdul-Rahman OA, Baynam G. Bleyl SB, Brady PD, Brechpot J, Chen CP, Devriendt K, Gillessen-Kaesbach G, Grix AW, Rope AF, Shimokawa O, Strauss B, Wieczorek D, Zackai EH, Coletti CM, Maalouf FI, Noonan KM, Park JH, Tracy AA, Lee C, Donahoe PK, Pober BR.  Congenital diaphragmatic hernia interval on chromosome 8p23.1 characterized by genetics and protein interaction networks.  Am J Med Genet A 2012; 158A: 3148-3158.

1952 Lopez Del Amo JM, Fink U, Dasari M, Grelle G, Wanker EE, Bieschke J, Reif B.  Structural Properties of EGCG-Induced, Nontoxic Alzheimer's Disease A? Oligomers. J Mol Biol. 2012 Jan 28. [Epub ahead of print]..

1951 Lu X, Wang L, Chen S, He L, Yang X, Shi Y, Cheng J, Zhang L, Gu CC, Huang J, Wu T, Ma Y, Li J, Cao J, Chen J, Ge D, Fan Z, Li Y, Zhao L, Li H, Zhou X, Chen L, Liu D, Chen J, Duan X, Hao Y, Wang L, Lu F, Liu Z, Yao C, Shen C, Pu X, Yu L, Fang X, Xu L, Mu J, Wu X, Zheng R, Wu N, Zhao Q, Li Y, Liu X, Wang M, Yu D, Hu D, Ji X, Guo D, Sun D, Wang Q, Yang Y, Liu F, Mao Q, Liang X, Ji J, Chen P, Mo X, Li D, Chai G, Tang Y, Li X, Du Z, Liu X, Dou C, Yang Z, Meng Q, Wang D, Wang R, Yang J, Schunkert H, Samani NJ, Kathiresan S, Reilly MP, Erdmann J; Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis(CARDIoGRAM) Consortium, Peng X, Wu X, Liu D, Yang Y, Chen R, Qiang B, Gu D. Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat Genet. 2012 Jul 1;44(8):890-4.

1950 Lubura M, Hesse D, Neumann N, Scherneck S, Wiedmer P, Schürmann A.  Non-invasive quantification of white and brown adipose tissues and liver fat content by computed tomography in mice.  PLoS One. 7:e37026 (2012).

1949 Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke S, Wray NR, Lewis CM, Hamilton SP, Weissman MM, Breen G, Byrne EM, Blackwood DH, Boomsma DI, Cichon S, Heath AC, Holsboer F, Lucae S, Madden PA, Martin NG, McGuffin P, Muglia P, Noethen MM, Penninx BP, Pergadia ML, Potash JB, Rietschel M, Lin D, Müller-Myhsok B, Shi J, Steinberg S, Grabe HJ, Lichtenstein P, Magnusson P, Perlis RH, Preisig M, Smoller JW, Stefansson K, Uher R, Kutalik Z, Tansey KE, Teumer A, Viktorin A, Barnes MR, Bettecken T, Binder EB, Breuer R, Castro VM, Churchill SE, Coryell WH, Craddock N, Craig IW, Czamara D, De Geus EJ, Degenhardt F, Farmer AE, Fava M, Frank J, Gainer VS, Gallagher PJ, Gordon SD, Goryachev S, Gross M, Guipponi M, Henders AK, Herms S, Hickie IB, Hoefels S, Hoogendijk W, Hottenga JJ, Iosifescu DV, Ising M, Jones I, Jones L, Jung-Ying T, Knowles JA, Kohane IS, Kohli MA, Korszun A, Landen M, Lawson WB, Lewis G, Macintyre D, Maier W, Mattheisen M, McGrath PJ, McIntosh A, McLean A, Middeldorp CM, Middleton L, Montgomery GM, Murphy SN, Nauck M, Nolen WA, Nyholt DR, O'Donovan M, Oskarsson H, Pedersen N, Scheftner WA, Schulz A, Schulze TG, Shyn SI, Sigurdsson E, Slager SL, Smit JH, Stefansson H, Steffens M, Thorgeirsson T, Tozzi F, Treutlein J, Uhr M, van den Oord EJ, Van Grootheest G, Völzke H, Weilburg JB, Willemsen G, Zitman FG, Neale B, Daly M, Levinson DF, Sullivan PF.  A mega-analysis of genome-wide association studies for major depressive disorder.  Mol Psychiatry. 2013 Apr;18(4):497-511. doi: 10.1038/mp.2012.21.

1948 Malinowsky K, Raychaudhuri M, Buchner T, Thulke S, Wolff C, Höfler H, Becker KF, Avril S. Common protein biomarkers assessed by reverse phase protein arrays show considerable intratumoral heterogeneity in breast cancer tissues. PLoS One.  2012;7(7):e40285. doi: 10.1371/journal.pone.0040285.

1947 Malinowsky K, Wolff C, Berg D, Schuster T, Walch A, Bronger H, Mannsperger H,  Schmidt C, Korf U, Höfler H, Becker KF. uPA and PAI-1-Related Signaling Pathways  Differ between Primary Breast Cancers and Lymph Node Metastases. Transl Oncol. 2012 Apr;5(2):98-104.

1946 Marcelin B, Liu Z, Chen Y, Lewis AS, Becker A, McClelland S, Chetkovich DM, Migliore M, Baram TZ, Esclapez M, Bernard C.  Dorsal-ventral differences in intrinsic properties in developing CA1 pyramidal cells.  J Neurosci, 32(11):3736-3747, 2012.

1945 Marcelin B, Lugo JN, Brewster AL, Liu Z, Lewis AS, McClelland S, Chetkovich DM, Baram TZ, Anderson AE, Becker A, Esclapez M, Bernard C.  Differential dorso-ventral distributions of Kv4.2 and HCN proteins confer distinct integrative properties to hippocampal CA1 pyramidal cell distal dendrites.  J Biol Chem, 287(21):17656-17661, 2012.

1944 Marcinowski L, Lidschreiber M, Windhager L, Rieder M, Bosse JB, Rädle B, Bonfert T, Györy I, de Graaf M, Prazeres da Costa O, Rosenstiel P, Friedel CC, Zimmer R, Ruzsics Z, Dölken L. Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection. PLoS Pathogens 2012 Sep;8(9):e1002908.

1943 Marcinowski L, Tanguy M, Krmpotic A, Rädle B, Juranic V, Tuddenham L, Chane-Woon-Ming B, Ruzsics Z, Erhard F, Benkartek C, Babic M, Zimmer R, Trgovcich J, Koszinowski UH, Jonjic S, Pfeffer S, Dölken L. Degradation of cellular miR-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo.  PLoS Pathog. 2012 Feb;8(2):e1002510. Epub 2012 Feb 9.

1942 Martin M, Müller K, Cadenas C, Hermes M, Zink M, Hengstler JG, Käs JA.  ERBB2overexpression triggers transient high mechanoactivity of breast tumor cells. Cytoskeleton (Hoboken). 2012 May;69(5):267-77. doi: 10.1002/cm.21023. 

1941 Martz K., A. Dorn, B. Baur, V. Schattel, M. Goettert, S. Mayer-Wrangowski, D. Rauh, S.A. Laufer.  Targeting the hinge glycine flip and the activation loop: novel approach to potent p38? inhibitors.  J Med Chem, 2012, 55(17):7862-74.

1940 Mattheisen M, Mühleisen TW, Strohmaier J, Treutlein J, Nenadic I, Alblas M, Meier S, Degenhardt F, Herms S, Hoffmann P, Witt SH, Giegling I, Sauer H, Schulze TG, Rujescu D, Nöthen MM, Rietschel M, Cichon S.  Genetic variation at the synaptic vesicle gene SV2A is associated with schizophrenia. S Schizophr Res. 2012 Nov;141(2-3):262-5. doi: 10.1016/j.schres.2012.08.027.

1939 Mayer-Wrangowski, S., D. Rauh. Symbiose aus Chemie und Medizin - Zielgerichtet gegen Krebs. BIOspektrum, 2012, 18(4):376:79.

1938 Mayr JA, Haack TB, Graf E, Zimmermann FA, Wieland T, Haberberger B, Superti-Furga A, Kirschner J, Steinmann B, Baumgartner MR, Moroni I, Lamantea E, Zeviani M, Rodenburg RJ, Smeitink J, Strom TM, Meitinger T, Sperl W, Prokisch H.  Lack of the mitochondrial protein acylglycerol kinase causes Sengers syndrome.  Am J Hum Genet. 2012 Feb 10;90(2):314-20. Epub 2012 Jan 26. PubMed PMID: 22284826; PubMed Central PMCID: PMC3276657.

1937 Meder B, Katus HA.  Clinical and genetic aspects of hypertrophic and dilated cardiomyopathy.  Internist 2012 [Epub ahead of print].

1936 Meesters C, Leber M, Herold C, Angisch M, Mattheisen M, Drichel D, Lacour A, Becker T. Quick,  'imputation-free' meta-analysis with proxy-SNPs.  BMC Bioinformatics. 2012 Sep 12;13:231. doi: 10.1186/1471-2105-13-231.

1935 Meier S, Mattheisen M, Vassos E, Strohmaier J, Treutlein J, Josef F, Breuer R, Degenhardt F, Mühleisen TW, Müller-Myhsok B, Steffens M, Schmael C, McMahon FJ; Bipolar Disorder Genome Study (BiGS) Consortium, Nöthen MM, Cichon S, Schulze TG, Rietschel M, Kelsoe JR, Greenwood TA, Nievergelt CM, Barrett TB, McKinney R, Shilling PD, Schork NJ, Smith EN, Bloss CS, Nurnberger J, Edenberg HJ, Foroud T, Koller DL, Gershon ES, Liu CY, Badner JA, Scheftner W, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon F, Chen DT, Schulze TG, Berrettini W, Potash JB, Zandi PP, Mahon PB, McInnis M, Craig D, Szelinger S. Genome-wide significant association between a 'negative mood delusions' dimension in bipolar disorder and genetic variation on chromosome 3q26.1.  Transl Psychiatry. 2012 Sep 25;2:e165.

1934 Meier S, Strohmaier J, Breuer R, Mattheisen M, Degenhardt F, Muhleisen TW, Schulze TG, Nothen MM, Cichon S, Rietschel M, Wust S  Neuregulin 3 is associated with attention deficits in schizophrenia and bipolar disorder.  Int J Neuropsychopharmacol:1-8.

1933 Mellett M, Atzei P, Horgan A, Hams E, Floss T, Wurst W, Fallon PG, Moynagh PN.  Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia. 1.  Nat Commun. 2012;3:1119. doi: 10.1038/ncomms2127.

1932 Menke A, Arloth J, Pütz B, Weber P, Klengel T, Mehta D, Gonik M, Rex-Haffner M, Rubel J, Uhr M, Lucae S, Deussing JM, Müller-Myhsok B, Holsboer F, Binder EB.  Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients.  Neuropsychopharmacology. 2012 May;37(6):1455-64.

1931 Menke A, Domschke K, Czamara D, Klengel T, Hennings J, Lucae S, Baune BT, Arolt V, Müller-Myhsok B, Holsboer F, Binder EB.  Genome-wide association study of antidepressant treatment-emergent suicidal ideation.  Neuropsychopharmacology. 2012 Feb;37(3):797-807.

1930 Menke A, Sämann P, Kloiber S, Czamara D, Lucae S, Hennings J, Heck A, Kohli MA, Czisch M, Müller-Myhsok B, Holsboer F, Binder EB.  Polymorphisms within the metabotropic glutamate receptor 1 gene are associated with depression phenotypes.  Psychoneuroendocrinology. 2012 Apr;37(4):565-75.

1929 Metzeler KH, Heilmeier B, Edmaier KE, Rawat VP, Dufour A, Döhner K, Feuring-Buske M, Braess J, Spiekermann K, Büchner T, Sauerland MC, Döhner H, Hiddemann W, Bohlander SK, Schlenk RF, Bullinger L, Buske C.  High expression of lymphoid enhancer-binding factor-1 (LEF1) is a novel favorable prognostic factor in cytogenetically normal acute myeloid leukemia.  Blood. 2012;120:2118-2126.

1928 Meyer D, Voigt A, Widmayer P, Borth H, Huebner S, Breit A, Marschall S, Hrabé de Angelis M, Boehm U, Meyerhof W, Gudermann T, Boekhoff I.  Expression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²? and cAMP concentrations in spermatozoa.  PLoS One. 2012;7(2):e32354. doi: 10.1371/journal.pone.0032354.

1927 Meyer M, Ortiz O, Hrabé de Angelis M, Wurst W, Kühn R.  Modeling disease mutations by gene targeting in one-cell mouse embryos.  Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9354-9.

1926 Milde T, Hielscher T, Witt H, Kool M, Mack SC, Deubzer HE, Oehme I, Lodrini M, Benner A, Taylor MD, von Deimling A, Kulozik AE, Pfister SM, Witt O, Korshunov A.  Nestin expression identifies ependymoma patients with poor outcome.  Brain Pathol. 2012 Nov;22(6):848-60. doi: 10.1111/j.1750-3639.2012.00600.x. Epub 2012 May 30.

1925 Milde T, Kleber S, Korshunov A, Witt H, Hielscher T, Koch P, Kopp HG, Jugold M, DEUBZER HE, Oehme I, Lodrini M, Gröne HJ, Benner A, Brüstle O, Gilbertson RJ, von Deimling A, Kulozik AE, Pfister SM, Martin-Villalba A, WITT O.

1924 Milde T, Lodrini M, Savelyeva L, Korshunov A, Kool M, Brueckner LM, Antunes AS, Oehme I, Pekrun A, Pfister SM, Kulozik AE, Witt O, Deubzer HE.  HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment.  J Neurooncol. 2012 Dec;110(3):335-48. PMID:23054560.

1923 Mills RE et al. (2012).  Mapping copy number variation by population-scale genome sequencing.  Nature 470(7332):59-65.

1922 Miró X, Meier S, Dreisow ML, Frank J, Strohmaier J, Breuer R, Schmäl C, Albayram Ö, Pardo-Olmedilla MT, Mühleisen TW, Degenhardt FA, Mattheisen M, Reinhard I, Bilkei-Gorzo A, Cichon S, Seidenbecher C, Rietschel M, Nöthen MM, Zimmer A.  Studies in humans and mice implicate neurocan in the etiology of mania.  Am J Psychiatry. 2012 Sep;169(9):982-90. doi: 10.1176/appi.ajp.2012.11101585.

1921 Mittag F, Büchel F, Saad M, Jahn A, Schulte C, Bochdanovits Z, Simón-Sánchez J, Nalls MA, Keller M, Hernandez D, Gibbs R, Lesage S, Brice A, Heutink P, Martinez M, Wood NW, Hardy J, Singleton AB, Zell A, Gasser T, and Sharma M.  Use of Support Vector Machines for Disease Risk Prediction in Genome-Wide Association Studies: Concerns and Opportunities.  Hum Mut, June 2012. doi:10.1002/humu.22161.

1920 Molander A, Vengeliene V, Heilig M, Wurst W, Deussing JM, Spanagel R. Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking.  Neuropsychopharmacology. 37:1047-56.

1919 Molenaar JJ, Domingo-Fernández R, Ebus ME, Lindner S, Koster J, Drabek K, Mestdagh P, van Sluis P, Valentijn LJ, van Nes J, Broekmans M, Haneveld F, Volckmann R, Bray I, Heukamp L, Sprüssel A, Thor T, Kieckbusch K, Klein-Hitpass L, Fischer M, Vandesompele J, Schramm A, van Noesel MM, Varesio  L, Speleman F, Eggert A, Stallings RL, Caron HN, Versteeg R, Schulte JH LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression.  Nat Genet. 2012 Nov;44(11):1199-206. doi: 10.1038/ng.2436. Epub 2012 Oct 7.

1918 Morak M, Attarbaschi A, Fischer S, Nassimbeni C, Grausenburger R, Bastelberger S, Krentz S, Cario G, Kasper D, Schmitt K, Russell LJ, Pötschger U, Stanulla M, Eckert C, Mann G, Haas OA, Panzer-Grümayer R.  Small sizes and indolent evolutionary dynamics challenge the potential role of P2RY8-CRLF2-harboring clones as main relapse-driving force in childhood ALL.  Blood. 2012, 120:5134-42.

1917 Morris AP, Voight BF, Teslovich TM, Ferreira T, Segrè AV, Steinthorsdottir V, Strawbridge RJ, Khan H, Grallert H, Mahajan A, Prokopenko I, Kang HM, Dina C, Esko T, Fraser RM, Kanoni S, Kumar A, Lagou V, Langenberg C, Luan J, Lindgren CM, Müller-Nurasyid M, Pechlivanis S, Rayner NW, Scott LJ, Wiltshire S, Yengo L, Kinnunen L, Rossin EJ, Raychaudhuri S, Johnson AD, Dimas AS, Loos RJ, Vedantam S, Chen H, Florez JC, Fox C, Liu CT, Rybin D, Couper DJ, Kao WH, Li M, Cornelis MC, Kraft P, Sun Q, van Dam RM, Stringham HM, Chines PS, Fischer K, Fontanillas P, Holmen OL, Hunt SE, Jackson AU, Kong A, Lawrence R, Meyer J, Perry JR, Platou CG, Potter S, Rehnberg E, Robertson N, Sivapalaratnam S, Stan?áková A, Stirrups K, Thorleifsson G, Tikkanen E, Wood AR, Almgren P, Atalay M, Benediktsson R, Bonnycastle LL, Burtt N, Carey J, Charpentier G, Crenshaw AT, Doney AS, Dorkhan M, Edkins S, Emilsson V, Eury E, Forsen T, Gertow K, Gigante B, Grant GB, Groves CJ, Guiducci C, Herder C, Hreidarsson AB, Hui J, James A, Jonsson A, Rathmann W, Klopp N, Kravic J, Krjut?kov K, Langford C, Leander K, Lindholm E, Lobbens S, Männistö S, Mirza G, Mühleisen TW, Musk B, Parkin M, Rallidis L, Saramies J, Sennblad B, Shah S, Sigurðsson G, Silveira A, Steinbach G, Thorand B, Trakalo J, Veglia F, Wennauer R, Winckler W, Zabaneh D, Campbell H, van Duijn C, Uitterlinden AG, Hofman A, Sijbrands E, Abecasis GR, Owen KR, Zeggini E, Trip MD, Forouhi NG, Syvänen AC, Eriksson JG, Peltonen L, Nöthen MM, Balkau B, Palmer CN, Lyssenko V, Tuomi T, Isomaa B, Hunter DJ, Qi L; Wellcome Trust Case Control Consortium; Meta-Analyses of Glucose and Insulin-related traits Consortium (MAGIC) Investigators; Genetic Investigation of ANthropometric Traits (GIANT) Consortium; Asian Genetic Epidemiology Network?Type 2 Diabetes (AGEN-T2D) Consortium; South Asian Type 2 Diabetes (SAT2D) Consortium, Shuldiner AR, Roden M, Barroso I, Wilsgaard T, Beilby J, Hovingh K, Price JF, Wilson JF, Rauramaa R, Lakka TA, Lind L, Dedoussis G, Njølstad I, Pedersen NL, Khaw KT, Wareham NJ, Keinanen-Kiukaanniemi SM, Saaristo TE, Korpi-Hyövälti E, Saltevo J, Laakso M, Kuusisto J, Metspalu A, Collins FS, Mohlke KL, Bergman RN, Tuomilehto J, Boehm BO, Gieger C, Hveem K, Cauchi S, Froguel P, Baldassarre D, Tremoli E, Humphries SE, Saleheen D, Danesh J, Ingelsson E, Ripatti S, Salomaa V, Erbel R, Jöckel KH, Moebus S, Peters A, Illig T, de Faire U, Hamsten A, Morris AD, Donnelly PJ, Frayling TM, Hattersley AT, Boerwinkle E, Melander O, Kathiresan S, Nilsson PM, Deloukas P, Thorsteinsdottir U, Groop LC, Stefansson K, Hu F, Pankow JS, Dupuis J, Meigs JB, Altshuler D, Boehnke M, McCarthy MI; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium.  Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.  Nat Genet. 2012 Sep;44(9):981-90. doi: 10.1038/ng.2383. Epub 2012 Aug 12.

1916 Moskalev, E.A., Luckert, K., Vorobjev, I.A., Mastitsky, S.E., Gladkikh, A.A., Stephan, A., Schrenk, M. Pötz, O., Joos, T.O. & Hoheisel, J.D.  Concurrent epigenetic silencing of Wnt/?-catenin pathway inhibitor genes in B-cell chronic lymphocytic leukemia.  BMC Cancer 12, 213.

1915 Moskalev, E.A., Schubert, M. & Hoheisel, J.D. RNA-directed epigenomic reprogramming ? an emerging principle of a more targeted cancer therapy? Genes Chrom.  Cancer 51, 105-110.

1914 Mössner R, Schuhmacher A, Wagner M, Lennertz L, Steinbrecher A, Quednow BB, Rujescu D, Rietschel M, Maier W.  The schizophrenia risk gene ZNF804A influences the antipsychotic response of positive schizophrenia symptoms.  Eur Arch Psychiatry Clin Neurosci. 2012 Apr;262(3):193-7. doi: 10.1007/s00406-011-0235-1.

1913 Motsch N., Imig J., Zhu J.Y., Barth S., Reineke T., Tinguely M., Dueck A., Meister G., Renner C. & Graesser F.  MicroRNA profiling of Epstein-Barr Virus-associated NK/T-cell lymphomas by deep sequencing.  Plos One, 7(8):e42193.

1912 Mühleisen TW, Mattheisen M, Strohmaier J, Degenhardt F, Priebe L, Schultz CC, Breuer R, Meier S, Hoffmann P; GROUP Investigators, Rivandeneira F, Hofman A, Uitterlinden AG, Moebus S, Gieger C, Emeny R, Ladwig KH, Wichmann HE, Schwarz M, Kammerer-Ciernioch J, Schlösser RG, Nenadic I, Sauer H, Mössner R, Maier W, Rujescu D, Lange C, Ophoff RA, Schulze TG, Rietschel M, Nöthen MM, Cichon S. Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder. Schizophr Res. 2012 Apr 10. [Epub ahead of print]

1911 Mühlhaus J, Pütter C, Brumm H, Grallert H, Illig T, Scherag S, Reinehr T, Pott W, Albayrak Ö, Wang HJ, Bau AM, Wiegand S, Grüters A, Krude H, Hebebrand J, Hinney A, Biebermann H, Scherag A.  Do common variants separate between obese melanocortin-4 receptor gene mutation carriers and non-carriers? The impact of cryptic relatedness.  Horm Res Paediatr. 2012;77(6):358-68. doi: 10.1159/000338999. Epub 2012 Jun 9. PubMed PMID: 22688572. 

1910 Mulaw MA, Krause AJ, Deshpande AJ, Krause LF, Rouhi A, La Starza R, Borkhardt A, Buske C, Mecucci C, Ludwig WD, Lottaz C, Bohlander SK.  CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12.  Leukemia. 2012 May;26(5):1012-9. doi: 10.1038/leu.2011.307. Epub 2011 Nov 8.

1909 Müller T, Gessi M, Waha A, Isselstein L J, Luxen D, Freihoff D, Freihoff J, Becker A, Simon M, Hammes J, Denkhaus D, zur Mühlen A, Pietsch T and Waha A.  Nuclear exclusion of TET is associated with loss of 5-hydroxymethylcytosine in IDH wild-type gliomas.  Am J Pathol. 2012 Aug;181(2):675-83.

1908 Müller TD, Greene BH, Bellodi L, Cavallini MC, Cellini E, Bella DD, Ehrlich S, Erzegovesi S, Estivill X, Fernández-Aranda F, Fichter M, Fleischhaker C, Scherag S, Gratacòs M, Grallert H, Herpertz-Dahlmann B, Herzog W, Illig T, Lehmkuhl U, Nacmias B, Ribasés M, Ricca V, Schäfer H, Scherag A, Sorbi S, Wichmann HE, Hebebrand J, Hinney A.  Fat Mass and Obesity Associated Gene (FTO) in Eating Disorders: Evidence for Association of the rs9939609 Obesity Risk Allele with Bulimia nervosa and Anorexia nervosa.  Obes Facts 2012; 5(3): 408-419

1907 Müssel C, Lausser L, Maucher M, Kestler HA.  Multi-Objective parameter selection for classifiers.  Journal of Statistical Software. 2012; 46(5):1?27. 

1906 Mutschler J, Abbruzzese E, Witt SH, Dirican G, Nieratschker V, Frank J, Grosshans M, Rietschel M, Kiefer F.  Functional polymorphism of the dopamine ?-hydroxylase gene is associated with increased risk of disulfiram-induced adverse effects in alcohol-dependent patients.  J Clin Psychopharmacol. 2012 Aug;32(4):578-80. doi: 10.1097/JCP.0b013e31825ddbe6.

1905 Najmabadi H, Hu H, Garshasbi M, Zemojtel T, Abedini SS, Chen W, Hosseini M, Behjati F, Haas S, Jamali P, Zecha A, Mohseni M, Püttmann L, Vahid LN, Jensen C, Moheb LA, Bienek M, Larti F, Mueller I, Weissmann R, Darvish H, Wrogemann K, Hadavi V, Lipkowitz B, Esmaeeli-Nieh S, Wieczorek D, Kariminejad R, Firouzabadi SG, Cohen M, Fattahi Z, Rost I, Mojahedi F, Hertzberg C, Dehghan A, Rajab A, Banavandi MJ, Hoffer J, Falah M, Musante L, Kalscheuer V, Ullmann R, Kuss AW, Tzschach A, Kahrizi K, Ropers HH.  Deep sequencing reveals 50 novel genes for recessive cognitive disorders. Nature. 2011 Sep 21;478(7367):57-63. doi: 10.1038/nature10423.

1904 Nees F, Tzschoppe J, Patrick CJ, Vollstädt-Klein S, Steiner S, Poustka L, Banaschewski T, Barker GJ, Büchel C, Conrod PJ, Garavan H, Heinz A, Gallinat J, Lathrop M, Mann K, Artiges E, Paus T, Poline JB, Robbins TW, Rietschel M, Smolka MN, Spanagel R, Struve M, Loth E, Schumann G, Flor H; IMAGEN Consortium.  Determinants of early alcohol use in healthy adolescents: the differential contribution of neuroimaging and psychological factors.  Neuropsychopharmacology. 2012 Mar;37(4):986-95. doi: 10.1038/npp.2011.282.

1903 Netzer C, Rahnenführer J.   Sample size estimation for cancer progression models. International Journal of  Computational Bioscience. 2012, Vol.1, 1:10.

1902 Neuhann TM, Müller D, Hackmann K, Holzinger S, Schrock E, Di Donato N.  A further patient with van Maldergem syndrome.  Eur J Med Genet. 2012 Mar 13. PMID:22469822.

1901 Ng BG, Hackmann K, Jones MA, Eroshkin AM, He P, Wiliams R, Bhide S, Cantagrel V, Gleeson JG, Paller AS, Schnur RE, Tinschert S, Zunich J, Hegde MR, Freeze HH.  Mutations in the Glycosylphosphatidylinositol Gene PIGL Cause CHIME Syndrome.  Am J Hum Genet. 2012 Apr 6;90(4):685-8. PMID:22444671.

1900 Nieratschker V, Grosshans M, Frank J, Strohmaier J, von der Goltz C, El-Maarri O, Witt SH, Cichon S, Nöthen MM, Kiefer F, Rietschel M.  Epigenetic alteration of the dopamine transporter gene in alcohol-dependent patients is associated with age.  Addict Biol. 2012 Apr 16. doi: 10.1111/j.1369-1600.2012.00459.

1899 Noori H.R.  Mathematical Modeling of Neurochemical Responses to Alcohol, 2012 Alcohol Clin Exp Res, 36 Suppl 2: 20A.

1898 Noori H.R.  Multi-Scale Modeling of Complex Neuronal Networks: a view Towards Striatal Pattern Formations J Biol Phys 38(4):597-606.

1897 Noori H.R., R. Spanagel, A. Hansson. Neurocircuitry for Modeling Drug Effects Addict Biol 17(5):827-864.

1896 Noori H.R., S. Fliegel, I. Brand, R. Spanagel. The impact of Acetylcholinesterase Inhibitors on the Extracellular Concentrations in the Adult Rat Brain: A Meta- Analysis Synapse 66(10): 893-901.

1895 Oeltze St, Klemm P, Hillert R, Preim B, Schubert W Visualization and Exploration of 3D Toponome Data.  VCBM 2012 pp. 115-122. doi: 10.2312/VCBM/VCBM12/115-122.

1894 Okada Y, Sim X, Go MJ, Wu JY, Gu D, Takeuchi F, Takahashi A, Maeda S, Tsunoda T, Chen P, Lim SC, Wong TY, Liu J, Young TL, Aung T, Seielstad M, Teo YY, Kim YJ, Lee JY, Han BG, Kang D, Chen CH, Tsai FJ, Chang LC, Fann SJ, Mei H, Rao DC, Hixson JE, Chen S, Katsuya T, Isono M, Ogihara T, Chambers JC, Zhang W, Kooner JS; KidneyGen Consortium; CKDGen Consortium, Albrecht E; GUGC consortium, Yamamoto K, Kubo M, Nakamura Y, Kamatani N, Kato N, He J, Chen YT, Cho YS, Tai ES, Tanaka T. Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations. Nat Genet 2012;44:904-909.

1893 Olbrich H, Schmidts M, Werner C, Onoufriadis A, Loges NT, Raidt J, Banki NF, Shoemark A, Burgoyne T, Al Turki S, Hurles ME; UK10K Consortium, Köhler G, Schroeder J, Nürnberg G, Nürnberg P, Chung EM, Reinhardt R, Marthin JK, Nielsen KG, Mitchison HM, Omran H.  Recessive HYDIN mutations cause primary ciliary dyskinesia without randomization of left-right body asymmetry. Am J Hum Genet. 2012 Oct 5;91(4):672-84. doi: 10.1016/j.ajhg.2012.08.016. Epub 2012 Sep 27. PubMed PMID: 23022101.

1892 Olszewski PK, Rozman J, Jacobsson JA, Rathkolb B, Strömberg S, Hans W, Klockars A, Alsiö J, Risérus U, Becker L, Hölter SM, Elvert R, Erhardt N, Gailus-Durner V, Fuchs H, Fredriksson R, Wolf E, Klopstock T, Wurst W, Levine AS, Marcus C, Hrabé de Angelis M, Klingenspor M, Schiöth HB, Kilimann MW (2012):  Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans.  PLoS Genet. 8(3), e1002568 doi:10.1371/journal.pgen.1002568.

1891 Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, Trump S, Schumacher T, Jestaedt L, Schrenk D, Weller M, Jugold M, Guillemin GJ, Miller CL, Lutz C, Radlwimmer B, Lehmann I, von Deimling A, Wick W, Platten M.  An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.  Nature. 2011 Oct 5;478(7368):197-203. doi: 10.1038/nature10491.

1890 Palada V, Terzic J, Mazzulli J, Bwala G, Hagenah J, Peterlin B, Hung AY, Klein C, Krainc D.  Histamine N-methyltransferase Thr105Ile Polymorphism is associated with Parkinson's disease.  Neurobiol Aging 2012;33(4):836e1-3.

1889 Panaccione R, Hibi T, Peyrin-Biroulet L, Schreiber S. Implementing changes in clinical practice to improve the management of Crohn's disease.<http://www.ncbi.nlm.nih.gov/pubmed/22463930> J Crohns Colitis. 2012 Feb;6 Suppl 2:S235-42. doi: 10.1016/S1873-9946(12)60503-0.

1888 Panizzi JR, Becker-Heck A, Castleman VH, Al-Mutairi DA, Liu Y, Loges NT, Pathak N, Austin-Tse C, Sheridan E, Schmidts M, Olbrich H, Werner C, Häffner K, Hellman N, Chodhari R, Gupta A, Kramer-Zucker A, Olale F, Burdine RD, Schier AF, O'Callaghan C, Chung EM, Reinhardt R, Mitchison HM, King SM, Omran H, Drummond IA. CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms. Nat Genet. 2012 May 13;44(6):714-9. doi: 10.1038/ng.2277. PubMed PMID: 22581229.

1887 Papenfort K, Podkaminski D, Hinton JC, Vogel J. The ancestral SgrS RNA discriminates horizontally acquired Salmonella mRNAs through a single G-U wobble pair. PNAS 109(13):E757-64 The ancestral SgrS RNA discriminates horizontally acquired Salmonella mRNAs through a single G-U wobble pair.  Proc Natl Acad Sci U S A PNAS 109(13):E757-64.

1886 Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA, Fuchsberger C, Olden M, Chen MH, Tin A, Taliun D, Li M, Gao X, Gorski M, Yang Q, Hundertmark C, Foster MC, O'Seaghdha CM, Glazer N, Isaacs A, Liu CT, Smith AV, O'Connell JR, Struchalin M, Tanaka T, Li G, Johnson AD, Gierman HJ, Feitosa M, Hwang SJ, Atkinson EJ, Lohman K, Cornelis MC, Johansson Å, Tönjes A, Dehghan A, Chouraki V, Holliday EG, Sorice R, Kutalik Z, Lehtimäki T, Esko T, Deshmukh H, Ulivi S, Chu AY, Murgia F, Trompet S, Imboden M, Kollerits B, Pistis G; CARDIoGRAM Consortium; ICBP Consortium; CARe Consortium; Wellcome Trust Case Control Consortium 2 (WTCCC2), Harris TB, Launer LJ, Aspelund T, Eiriksdottir G, Mitchell BD, Boerwinkle E, Schmidt H, Cavalieri M, Rao M, Hu FB, Demirkan A, Oostra BA, de Andrade M, Turner ST, Ding J, Andrews JS, Freedman BI, Koenig W, Illig T, Döring A, Wichmann HE, Kolcic I, Zemunik T, Boban M, Minelli C, Wheeler HE, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Nöthlings U, Jacobs G, Biffar R, Endlich K, Ernst F, Homuth G, Kroemer HK, Nauck M, Stracke S, Völker U, Völzke H, Kovacs P, Stumvoll M, Mägi R, Hofman A, Uitterlinden AG, Rivadeneira F, Aulchenko YS, Polasek O, Hastie N, Vitart V, Helmer C, Wang JJ, Ruggiero D, Bergmann S, Kähönen M, Viikari J, Nikopensius T, Province M, Ketkar S, Colhoun H, Doney A, Robino A, Giulianini F, Krämer BK, Portas L, Ford I, Buckley BM, Adam M, Thun GA, Paulweber B, Haun M, Sala C, Metzger M, Mitchell P, Ciullo M, Kim SK, Vollenweider P, Raitakari O, Metspalu A, Palmer C, Gasparini P, Pirastu M, Jukema JW, Probst-Hensch NM, Kronenberg F, Toniolo D, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Siscovick DS, van Duijn CM, Borecki I, Kardia SL, Liu Y, Curhan GC, Rudan I, Gyllensten U, Wilson JF, Franke A, Pramstaller PP, Rettig R, Prokopenko I, Witteman JC, Hayward C, Ridker P, Parsa A, Bochud M, Heid IM, Goessling W, Chasman DI, Kao WH, Fox CS. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet 2012;8:e1002584.

1885 Pedroso I, Lourdusamy A, Rietschel M, Nöthen MM, Cichon S, McGuffin P, Al-Chalabi A, Barnes MR, Breen G. Common Genetic Variants and Gene-Expression Changes Associated with Bipolar Disorder Are Over-Represented in Brain Signaling Pathway Genes. Biol Psychiatry. 2012 Apr 12. [Epub ahead of print]

1884 Peifer M, Fernández-Cuesta L, Sos ML, George J, Kasper LH, Seidel D, Plenker D, Leenders F, Sun R, Zander T, Menon R, Koker M, Dahmen I, Müller C, Di Cerbo V, Schildhaus HU, Altmüller J, Baessmann I, Becker C, De Wilde B, Vandesompele J, Böhm D, Ansén S, Gabler F, Wilkening I, Heynck S, Heuckmann JM, Lu X, Cibulskis K, Banerji S, Getz G, Park KS, Rauh D, Grütter C, Fischer M, Pasqualucci L, Wright G, Wainer Z,  Russell P, Petersen I, Chen Y, Stoelben E, Ludwig C, Schnabel P, Hoffmann H, Muley T, Brockmann M, Engel-Riedel W, Muscarella LA, Fazio VM, Groen H, Timens W, Sietsma H, Thunnissen E, Smit E, Heideman DAM, Snijders PJF, Cappuzzo F, Ligorio C, Damiani S, Field J, Solberg S, Brustugun OT, Lund-Iversen M, Sänger J, Clement JH, Soltermann A, Moch H, Weder W, Solomon B, Soria JC, Validire P, Besse B, Brambilla E, Brambilla C, Lantuejoul S, Lorimier P, Schneider PM, Hallek M, Pao W, Meyerson M, Sage J, Shendure J, Schneider R, Büttner R, Wolf J, Nürnberg P, Perner S, Heukamp LC, Brindle PK, Haas S, Thomas RK. Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.  Nat Genet, 2012, 44(10): 1104-1110.

1883 Peng C, Li N, Ng YK, Zhang J, Meier F, Theis FJ, Merkenschlager M, Chen W, Wurst W, Prakash N. 2.  A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.  J Neurosci. 2012 Sep 19;32(38):13292-308.

1882 Perez-Moreno P, Brambilla E, Thomas R, Soria JC.  Squamous cell carcinoma of the lung: molecular subtypes and therapeutic opportunities. Clin Cancer Res. 2012 May 1;18(9):2443-51. doi: 10.1158/1078-0432.CCR-11-2370. Epub 2012 Mar 8. Review.

1881 Pernhorst K, Raabe A, Niehusmann P, van Loo KM, Grote A, Hoffmann P, Cichon S, Sander T, Schoch S, Becker AJ.  Promoter variants determine ?-aminobutyric acid homeostasis-related gene transcription in human epileptic hippocampi.  J Neuropathol Exp Neurol. 2011 Dec;70(12):1080-8. doi: 10.1097/NEN.0b013e318238b9af.

1880 Perreau-Lenz S., V. Vengeliene, H.R. Noori, E. Merlo-Pich, M. Corsi, C. Corti and R. Spanagel. Inhibition of the Casein-kinase-1-delta Prevents Relapse-Like Alcohol Drinking Behaviour Neuropsychopharm 37(9):2121-2131.

1879 Perry JR, Voight BF, Yengo L, Amin N, Dupuis J, Ganser M, Grallert H, Navarro P, Li M, Qi L, Steinthorsdottir V, Scott RA, Almgren P, Arking DE, Aulchenko Y, Balkau B, Benediktsson R, Bergman RN, Boerwinkle E, Bonnycastle L, Burtt NP, Campbell H, Charpentier G, Collins FS, Gieger C, Green T, Hadjadj S, Hattersley AT, Herder C, Hofman A, Johnson AD, Kottgen A, Kraft P, Labrune Y, Langenberg C, Manning AK, Mohlke KL, Morris AP, Oostra B, Pankow J, Petersen AK, Pramstaller PP, Prokopenko I, Rathmann W, Rayner W, Roden M, Rudan I, Rybin D, Scott LJ, Sigurdsson G, Sladek R, Thorleifsson G, Thorsteinsdottir U, Tuomilehto J, Uitterlinden AG, Vivequin S, Weedon MN, Wright AF; MAGIC; DIAGRAM Consortium; GIANT Consortium, Hu FB, Illig T, Kao L, Meigs JB, Wilson JF, Stefansson K, van Duijn C, Altschuler D, Morris AD, Boehnke M, McCarthy MI, Froguel P, Palmer CN, Wareham NJ, Groop L, Frayling TM, Cauchi S.  Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.  PLoS Genet. 2012 May;8(5):e1002741. doi: 10.1371/journal.pgen.1002741. Epub 2012 May 31.

1878 Peterziel H, Müller J, Danner A, Barbus S, Liu HK, Radlwimmer B, Pietsch T,Lichter P, Schütz G, Hess J, Angel P. Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation.  Neuro Oncol. 2012 Apr;14(4):426-39. Epub 2012 Mar 6. PubMed PMID: 22394497; PubMed Central PMCID: PMC3309862.

1877 Petrakis S, Rasko T, Russ J, Friedrich RP, Stroedicke M, Riechers SP, Muehlenberg K, Moeller A, Reinhardt A, Vinayagam A, Schaefer MH, Boutros M, Tricoire H, Andrade-Navarro MA, Wanker EE.  Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1.  PLoS Genetics 8 (8): e1002897.

1876 Petri, T., Berchtold, E., Zimmer, R. and  C. Friedel.  Detection and correction of probe-level artefacts on microarrays BMC Bioinformatics. 2012 May 30;13:114. doi: 10.1186/1471-2105-13-114.

1875 Peyrin-Biroulet L, Billioud V, D'Haens G, Panaccione R, Feagan B, Panés J, Danese S, Schreiber S, Ogata H, Hibi T, Higgins PD, Beaugerie L, Chowers Y, Louis E, Steinwurz F, Reinisch W, Rutgeerts P, Colombel JF, Travis S, Sandborn WJ. Development of the Paris definition of early Crohn's disease for disease-modification trials: results of an international expert opinion process.<http://www.ncbi.nlm.nih.gov/pubmed/23211844> Am J Gastroenterol. 2012 Dec;107(12):1770-6. doi: 10.1038/ajg.2012.117.

1874 Philipp EE, Kraemer L, Mountfort D, Schilhabel M, Schreiber S, Rosenstiel P.  The Transcriptome Analysis and Comparison Explorer--T-ACE: a platform-independent, graphical tool to process large RNAseq datasets of non-model organisms.  Bioinformatics. 2012 Mar 15;28(6):777-83. Epub 2012 Jan 27.

1873 Piao X, Komazawa-Sakon S, Nishina T, Koike M, Piao JH, Ehlken H, Kurihara H, Hara M, Van Rooijen N, Schütz G, Uchiyama Y, Yagita H, Okumura K, He YW, Nakano H.  c-FLIP maintains tissue homeostasis by preventing apoptosis and programmed necrosis.  Sci Signal 2012; 5:ra93.

1872 Pihlajamäki J, Carles Lerin, Dorota Kaminska, Sari Venesmaa, Paula Itkonen, Tanner Boes, Thomas Floss, Joshua Schroeder, Farrell Dearie, Sarah Crunkhorn, Furkan Burak, Josep C. Jimenez-Chillaron, Tiina Kuulasmaa, Pekka Miettinen, Peter J. Park, Imad Nasser, Zhenwen Zhao, Zhaiyi Zhang, Yan Xu, Wolfgang Wurst, Hongmei Ren, Andrew J. Morris, Stefan Stamm, Allison B. Goldfine,Markku Laakso, and Mary Elizabeth Patti.  Response to Brosch et al.  Cell Metab. 2012 Mar 7;15(3):267-9. Cell Metabolism Letters.

1871 Pilsl, A. and Winklhofer, K.F. Parkin, PINK1 and mitochondrial integrity:Emerging concepts of mitochondrial dysfunction in Parkinson's Disease.  Acta Neuropathol., 123, 173-188.

1870 Pitsch J, Opitz T, Borm V, Woitecki A, Staniek M, Beck H, Becker AJ, Schoch S.  The presynaptic active zone protein RIM1? controls epileptogenesis following status epilepticus. J Neurosci. 2012 Sep 5;32(36):12384-95. doi: 10.1523/JNEUROSCI.0223-12.2012.

1869 Platt NJ, Gispert S, Auburger G, Cragg SJ. Striatal dopamine transmission is subtly modified in human A53T?-synuclein overexpressing mice. PLoS One. 2012;7(5):e36397.

1868 Plichta MM, Schwarz AJ, Grimm O, Morgen K, Mier D, Haddad L, Gerdes AB, Sauer C, Tost H, Esslinger C, Colman P, Wilson F, Kirsch P, Meyer-Lindenberg A. Test-retest reliability of evoked BOLD signals from a cognitive-emotive fMRI test battery. Neuroimage. 2012 Apr 15;60(3):1746-58. Epub 2012 Feb 8

1867 Potaczek DP, Kabesch M. Current concepts of IgE regulation and impact ofgenetic determinants. Clin Exp Allergy. 2012 Jan 30. doi:10.1111/j.1365-2222.2012.03953.x. [Epub ahead of print] PubMed PMID: 22417242.

1866 Power RA, Keers R, Ng MY, Butler AW, Uher R, Cohen-Woods S, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Hauser J, Henigsberg N, Maier W, Zobel A, Mors O, Placentino AS, Rietschel M, Souery D, Kozel D, Preisig M, Lucae S, Binder EB, Aitchison KJ, Tozzi F, Muglia P, Breen G, Craig IW, Farmer AE, Muller-Myhsok B, McGuffin P, Lewis CM  Dissecting the genetic heterogeneity of depression through age at onset.  Am J Med Genet B Neuropsychiatr Genet: epub ahead of print.

1865 Power RA, Wingenbach T, Cohen-Woods S, Uher R, Ng MY, Butler AW, Ising M, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Zobel A, Mors O, Placentino A, Rietschel M, Lucae S, Holsboer F, Binder EB, Keers R, Tozzi F, Muglia P, Breen G, Craig IW, Muller-Myhsok B, Kennedy JL, Strauss J, Vincent JB, Lewis CM, Farmer AE, McGuffin P  Estimating the heritability of reporting stressful life events captured by common genetic variants.  Psychol Med:1-7.

1864 Pozzi B, Amodio S, Lucano C, Sciullo A, Ronzoni S, Castelletti D, Adler T, Treise I, Betsholtz IH, Rathkolb B, Busch DH, Wolf E, Fuchs H, Gailus-Durner V, de Angelis MH, Betsholtz C, Casola S, Di Fiore PP, Offenhäuser N.  The endocytic adaptor Eps15 controls marginal zone B cell numbers.  PLoS One. 2012;7(11):e50818. doi: 10.1371/journal.pone.0050818.

1863 Priebe L, Degenhardt FA, Herms S, Haenisch B, Mattheisen M, Nieratschker V, Weingarten M, Witt S, Breuer R, Paul T, Alblas M, Moebus S, Lathrop M, Leboyer M, Schreiber S, Grigoroiu-Serbanescu M, Maier W, Propping P, Rietschel M, Nöthen MM, Cichon S, Mühleisen TW.  Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder.  Mol Psychiatry. 2012 Apr;17(4):421-32. doi: 10.1038/mp.2011.8.

1862 Prusty BK, Böhme L, Bergmann B, Siegl C, Krause E, Mehlitz A, Rudel T.  Imbalanced oxidative stress causes chlamydial persistence during non-productive human herpes virus co-infection. PLoS One. 2012;7(10):e47427. doi: 10.1371/journal.pone.0047427.

1861 Pusapati GV, Eiseler T, Rykx A, Vandoninck S, Derua R, Waelkens E, Van Lint J, von Wichert G, Seufferlein T.  Protein Kinase D Regulates RhoA Activity via Rhotekin Phosphorylation.  J Biol Chem. 2012 Mar 16;287(12):9473-83. Epub 2012 Jan 6.

1860 Quednow BB, Brinkmeyer J, Mobascher A, Nothnagel M, Musso F, Gründer G, Savary N, Petrovsky N, Frommann I, Lennertz L, Spreckelmeyer KN, Wienker TF, Dahmen N, Thuerauf N, Clepce M, Kiefer F, Majic T, Mössner R, Maier W, Gallinat J, Diaz-Lacava A, Toliat MR, Thiele H, Nürnberg P, Wagner M, Winterer G.  Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating.  Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6271-6. doi: 10.1073/pnas.1118051109. Epub 2012 Mar 26.

1859 R. Ruiss, S. Ohno, B. Steer, R. Zeidler and H. Adler. Murine gammaherpesvirus 68 glycoprotein 150 does not contribute to latency amplification in vivo.  Virology Journal, 9 (2012): 107.

1858 Raabe A, Schmitz AK, Pernhorst K, Grote A, von der Brelie C, Urbach H, Friedman A, Becker AJ, Elger CE, Niehusmann P.  Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions.  Epilepsia. 2012 Mar;53(3):539-48. doi: 10.1111/j.1528-1167.2012.03405.x. PMID: 22372630.

1857 Rachakonda, P.S., Bauer, A.S., Xie, H., Campa, D., Rizzato, C., Canzian, F., Beghelli, S., Greenhalf, W., Costello, E., Schanne, M. Heller, A., Scarpa, A., Neoptolemos, J.P., Werner, J., Büchler, M., Hoheisel, J.D., Hemminki, K., Giese, N. & Kumar, R. Somatic mutations in exocrine pancreatic tumors: association with patient survival.  PLoS ONE 8, e60870.

1856 Racz I, Markert A, Mauer D, Stoffel-Wagner B, Zimmer A.  Long-term ethanol effects on acute stress responses: Modulation by dynorphin.  Addict Biol. 2012 Sep 21. doi: 10.1111/j.1369-1600.2012.00494.

1855 Radermacher KA, Wingler K, Langhauser F, Altenhöfer S, Kleikers P, Hermans JJ, Hrabe de Angelis M, Kleinschnitz C, Schmidt HH.  Neuroprotection After Stroke by Targeting NOX4 As a Source of Oxidative Stress.  Antioxid Redox Signal. 2012 Oct 16. PMID: 22937798.

1854 Raedler D, Illi S, Pinto LA, von Mutius E, Illig T, Kabesch M, Schaub B.  IL10 polymorphisms influence neonatal immune responses, atopic dermatitis, and wheeze at age 3 years.  J Allergy Clin Immunol. 2013 Mar;131(3):789-96. doi:10.1016/j.jaci.2012.08.008. Epub 2012 Sep 27. PubMed PMID: 23021880.

1853 Ramírez F, Lawyer G, Albrecht M.  Novel search method for the discovery of functional relationships.  Bioinformatics. 2012 Jan 15;28(2):269-76.

1852 Rannikko EH, Vesterager LB, Shaik JH, Weber SS, Cornejo Castro EM, Fog K, Jensen PH, Kahle PJ.  Loss of DJ-1 protein stability and cytoprotective function by Parkinson's disease-associated proline-158 deletion.  J Neurochem. 2012 Dec 14. [Epub ahead of print].

1851 Rauch A, Wieczorek D, Graf E, Wieland T, Endele S, Schwarzmayr T, Albrecht B, Bartholdi D, Beygo J, Di Donato N, Dufke A, Cremer K, Hempel M, Horn D, Hoyer J, Joset P, Röpke A, Moog U, Riess A, Thiel CT, Tzschach A, Wiesener A, Wohlleber E, Zweier C, Ekici AB, Zink AM, Rump A, Meisinger C, Grallert H, Sticht H, Schenck A, Engels H, Rappold G, Schröck E, Wieacker P, Riess O, Meitinger T, Reis A, Strom TM.  Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study. Lancet. 2012; 380(9854):1674-82. doi: 10.1016/S0140-6736(12)61480-9.

1850 Rausch T, Jones DT, Zapatka M, Stütz AM, Zichner T, Weischenfeldt J, Jäger N, Remke M, Shih D, Northcott PA, Pfaff E, Tica J, Wang Q, Massimi L, Witt H, Bender S, Pleier S, Cin H, Hawkins C, Beck C, von Deimling A, Hans V, Brors B, Eils R, Scheurlen W, Blake J, Benes V, Kulozik AE, Witt O, Martin D, Zhang C, Porat R, Merino DM, Wasserman J, Jabado N, Fontebasso A, Bullinger L, Rücker FG, Döhner K, Döhner H, Koster J, Molenaar JJ, Versteeg R, Kool M, Tabori U, Malkin D, Korshunov A, Taylor MD, Lichter P, Pfister SM, Korbel JO.  Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations.  Cell. 2012 Jan 20;148(1-2):59-71.

1849 Rebane A, Zimmermann M, Aab A, Baurecht H, Koreck A, Karelson M, Abram K, Metsalu T, Pihlap M, Meyer N, Fölster-Holst R, Nagy N, Kemeny L, Kingo K, Vilo J, Illig T, Akdis M, Franke A, Novak N, Weidinger S, Akdis CA.  Mechanisms of IFN-?-induced apoptosis of human skin keratinocytes in patients with atopic dermatitis.  J Allergy Clin Immunol 2012; 129:1297-306.

1848 Reinisch W, Van Assche G, Befrits R, Connell W, D'Haens G, Ghosh S, Michetti P, Ochsenkühn T, Panaccione R, Schreiber S, Silverberg MS, Sorrentino D, van der Woude CJ, Vermeire S, Panes J.  Recommendations for the treatment of ulcerative colitis with infliximab: a gastroenterology expert group consensus.  J Crohns Colitis. 2012 Mar;6(2):248-58. Epub 2012 Jan 10.

1847 Richter GM, Graetz C, Pohler P, Nothnagel M, Dommisch H, Laine ML, Folwaczny M, Noack B, Eickholz P, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S, Schaefer AS.  Common genetic risk variants of TLR2 are not associated with periodontitis in large European case-control populations. J Clin Periodontol. 2012 Apr;39(4):315-22.

1846 Ridder S, Treutlein J, Nees F, Lang S, Diener S, Wessa M, Kroll A, Pohlack S, Cacciaglia R, Gass P, Schütz G, Schumann G, Flor H.  Brain activation during fear conditioning in humans depends on genetic variations related to functioning of the hypothalamic-pituitary-adrenal axis: first evidence from two independent subsamples.  Psychol Med. 2012 Mar 12:1-11. [Epub ahead of print].

1845 Rieder R, Reinhardt R, Sharma CM, Vogel J. Experimental tools to identify RNA-protein interactions in Helicobacter pylori RNA Biology 9(4):520-31

1844 Rieker C, Schober A, Bilbao A, Schütz G, Rodriguez Parkitna J.  Ablation of SRF in dopaminergic neurons exacerbates susceptibility towards MPTP-induced oxidative stress.  Eur J Neurosci. 2012; 35: 735-741. Epub 2012 February 23. Doi: 10.1111/j.1460-9568.2012.08003.

1843 Rietschel M, Mattheisen M, Degenhardt F; Genetic Risk and Outcome in Psychosis (GROUP Investigators), Mühleisen TW, Kirsch P, Esslinger C, Herms S, Demontis D,  Steffens M, Strohmaier J, Haenisch B, Breuer R, Czerski PM, Giegling I, Strengman E, Schmael C, Mors O, Mortensen PB, Hougaard DM, Ørntoft T, Kapelski P, Priebe L, Basmanav FF, Forstner AJ, Hoffman P, Meier S, Nikitopoulos J, Moebus S, Alexander M, Mössner R, Wichmann H-, Schreiber S, Rivandeneira F, Hofman A, Uitterlinden AG, Wienker TF, Schumacher J, Hauser J, Maier W, Cantor RM, Erk S, Schulze TG; SGENE-plus Consortium, Craddock N, Owen MJ, O'Donovan MC, Børglum AD, Rujescu D,  Walter H, Meyer-Lindenberg A, Nöthen NM, Ophoff RA, Cichon S.  Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe.  Mol Psychiatry. 2012 Sep;17(9):906-17.

1842 Rietschel M, Treutlein J.  The genetics of alcohol dependence.  Ann N Y Acad Sci. 2012 Nov 21. [Epub ahead of print].

1841 Ring J, Möhrenschlager M, Weidinger S.  Molecular genetics of atopic eczema.  Chem Immunol Allergy 2012;96:24-9.

1840 Rizzato, C., Campa, D., Giese, N., Werner, J., Rachakonda, S.P., Kumar, R., Schanné, M., Greenhalf, W., Costello, E., Khaw, K.T., Key, T.J., Siddiq, A., Lorenzo-Bermejo, J., Burwinkel, B., Neoptolemos, J.P., Büchler, M.W., Hoheisel, J.D., Bauer, A. & Canzian, F.  Pancreatic cancer susceptibility loci and their role in survival.  PLoS ONE 6, e27921. 

1839 Rizzato, C., Campa, D., Pezzilli, R., Soucek, P., Greenhalf, W., Capurso, G., Talar-Wojnarowska, R., Heller, A., Jamroziak, K., Khaw, K.-T., Key, T.J., Bambi, F., Landi, S., Vodickova, L., Büchler, M.W., Bugert, P., Vodicka, P., Neoptolemos, J.P., Werner, J., Hoheisel, J.D., Bauer, A.S., Giese, N. & Canzian, F. ABO blood groups and pancreatic cancer risk and survival: results from the PANcreatic Disease ReseArch (PANDoRA) consortium.  Oncol. Report 29, 1637-1644.

1838 Robert G, Puissant A, Dufies M, Marchetti S, Jacquel A, Cluzeau T, Colosetti P, Belhacene N, Kahle PJ, Da Costa CA, Luciano F, Checler F, Auberger P.  The caspase 6 derived N-terminal fragment of DJ-1 promotes apoptosis via increased ROS production.  Cell Death Differ. 2012 Nov;19(11):1769-78.

1837 Rosewich H, Thiele H, Ohlenbusch A, Maschke U, Altmüller J, Frommolt P, Zirn B, Ebinger F, Siemes H, Nürnberg P, Brockmann K, Gärtner J.  Heterozygous de-novo mutations in ATP1A3 in patients with alternating hemiplegia of childhood: a whole-exome sequencing gene-identification study.  Lancet Neurol. 2012 Sep;11(9):764-73. doi: 10.1016/S1474-4422(12)70182-5. Epub 2012 Jul 30.

1836 Rostovskaya M, Fu J, Obst M, Baer I, Weidlich S, Wang H, Smith AJH, Anastassiadis K and Stewart AF.  Transposon mediated BAC transgenesis in human ES cells (2012)  Nucleic Acids Res. 40, e150.

1835 Rothhaar TL, Grösgen S, Haupenthal VJ, Burg VK, Hundsdörfer B, Mett J, Riemenschneider M, Grimm HS, Hartmann T, Grimm MO.  Plasmalogens inhibit APP processing by directly affecting ?-secretase activity in Alzheimer's disease.  Scientific World Journal. 2012;2012:141240. doi: 10.1100/2012/141240. Epub 2012 Apr 1.

1834 Royer L, Stewart AF and Schroeder M.  Evaluating coverage and accuracy of protein interaction datasets with network compression (2012)  PLoS One, 7:e35729.

1833 Rubin D, Helwig U, Pfeuffer M, Auinger A, Ruether A, Matusch D, Darabaneanu S, Freitag-Wolf S, Nothnagel M, Schreiber S, Schrezenmeir J.  The effect of FABP2 promoter haplotype on response to a diet with medium-chain triacylglycerols.  Genes Nutr. 2012 Jul;7(3):437-45..

1832 Rücker FG, Schlenk RF, Bullinger L, Kayser S, Teleanu V, Kett H, Habdank M, Kugler CM, Holzmann K, Gaidzik VI, Paschka P, Held G, von Lilienfeld-Toal M, Lübbert M, Fröhling S, Zenz T, Krauter J, Schlegelberger B, Ganser A, Lichter P, Döhner K, Döhner H.  TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome.  Blood. 2012 Mar 1;119(9):2114-21.  

1831 S. Ohno, B. Steer, C. Sattler and H. Adler. Open reading frame 23 of murine gammaherpesvirus 68 is nonessential for in vitro and in vivo infection  Journal of General Virology, 93 (2012): 1076-1080.

1830 Sabrautzki S, Eva Janas, , Bettina Lorenz-Depiereux, Julia Calzada- Wack, Juan A. Aguilar-Pimentel, Birgit Rathkolb, Thure Adler, Christian 7 Cohrs, Wolfgang Hans, Susanne Diener, Helmut Fuchs, Valerie Gailus-Durner, Dirk H. Busch, Heinz Höfler, Markus Ollert, Tim Matthias Strom, Eckhard Wolf,  Frauke Neff, Martin Hrabe de Angelis.  An ENU mutagenesis derived mouse model with a dominant Jak1 mutation 1 resembling phenotypes of systemic autoimmune disease. Short title: New mouse model for systemic autoimmune disease.  Am J Pathology manuscript#AJP12_0541 In press.

1829 Sabrautzki S, Rubio-Aliaga I, Hans W, Fuchs H, Rathkolb B, Calzada-Wack J, Cohrs CM, Klaften M, Seedorf H, Eck S, Benet-Pagès A, Favor J, Esposito I, Strom TM, Wolf E, Lorenz-Depiereux B, Hrabé de Angelis M:  New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis.  Mamm Genome. 23, 416-30 (2012) DOI 10.1007/s00335-012-9397-z.

1828 Salem S, Bruck H, Bahlmann FH, Peter M, Passlick-Deetjen J, Kretschmer A, Steppan S, Volsek M, Kribben A, Nierhaus M, Jankowski V, Zidek W, Jankowski J.  Relationship between magnesium and clinical biomarkers on inhibition of vascular calcification.  Am J Nephrol. 2012;35(1):31-9. Epub 2011 Dec 15.

1827 Salm F, Cwiek P, Ghosal A, Lucia Buccarello A, Largey F, Wotzkow C, Höland K, Styp-Rekowska B, Djonov V, Zlobec I, Bodmer N, Gross N, Westermann F, Schäfer SC, Arcaro A.  RNA interference screening identifies a novel role for autocrine fibroblast growth factor signaling in neuroblastoma chemoresistance.  Oncogene. 2012 Oct 1. doi: 10.1038/onc.2012.416. [Epub ahead of print] PubMed PMID:23027129..

1826 Sandborn WJ, Colombel JF, Sands BE, Rutgeerts P, Targan SR, Panaccione R, Bressler B, Geboes K, Schreiber S, Aranda R, Gujrathi S, Luo A, Peng Y, Salter-Cid L, Hanauer SB. Abatacept for Crohn's disease and ulcerative colitis.<http://www.ncbi.nlm.nih.gov/pubmed/22504093> Gastroenterology. 2012 Jul;143(1):62-69.e4. doi: 10.1053/j.gastro.2012.04.010. Epub 2012 Apr 12.

1825 Sandborn WJ, Gasink C, Gao LL, Blank MA, Johanns J, Guzzo C, Sands BE, Hanauer SB, Targan S, Rutgeerts P, Ghosh S, de Villiers WJ, Panaccione R, Greenberg G, Schreiber S, Lichtiger S, Feagan BG; CERTIFI Study Group. Ustekinumab induction and maintenance therapy in refractory Crohn's disease.<http://www.ncbi.nlm.nih.gov/pubmed/23075178> N Engl J Med. 2012 Oct 18;367(16):1519-28. doi: 10.1056/NEJMoa1203572.

1824 Sarek, G. Enbaeck, J., Haas, J., Gessain, A. Laakkonen, P. and Ojala, P.  Regression of primary effusion lymphoma tumors in vivo requires the restoration of p53 function.  Oncogene 2012 Apr 2. doi: 10.1038/onc.2012.118.

1823 Sartorius T, Lutz SZ, Hoene M, Waak J, Peter A, Weigert C, Rammensee HG, Kahle PJ, Häring HU, Hennige AM.  Toll-like receptors 2 and 4 impair insulin-mediated brain activity by interleukin-6 and osteopontin and alter sleep architecture.  FASEB J. 2012 May;26(5):1799-809.

1822 Sato, D., Lionel, A. C., Prasad, A., Pinto, D., Walker, S., O'Connor, I., Russell, C., Drmic, I. E., Hamdan, F. F., Michaud, J. L., Endris, V., Roeth, R., Leblond, C. S., Delorme, R., Huguet, G., Leboyer, M., Maria Rastam, M., Gillberg, C., Stavropoulos, D. J., Anagonostou, E., Weksberg, R., Fombonne, E., Zwaigenbaum, L., Fernandez, B. A., Roberts, W., Rappold, G. A., Marshall, C. R., Bourgeron, T., Szatmari, P., Scherer, S. W. SHANK1 deletion in males with Autism Spectrum Disorder.  Am J Hum Genet. 2012, 90(5):879-87.

1821 Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, Balasubramanyam A, Barnard J, Bauer F, Baumert J, Bhangale T, Böhm BO, Braund PS, Burton PR, Chandrupatla HR, Clarke R, Cooper-DeHoff RM, Crook ED, Davey-Smith G, Day IN, de Boer A, de Groot MC, Drenos F, Ferguson J, Fox CS, Furlong CE, Gibson Q, Gieger C, Gilhuijs-Pederson LA, Glessner JT, Goel A, Gong Y, Grant SF, Grobbee DE, Hastie C, Humphries SE, Kim CE, Kivimaki M, Kleber M, Meisinger C, Kumari M, Langaee TY, Lawlor DA, Li M, Lobmeyer MT, Maitland-van der Zee AH, Meijs MF, Molony CM, Morrow DA, Murugesan G, Musani SK, Nelson CP, Newhouse SJ, O'Connell JR, Padmanabhan S, Palmen J, Patel SR, Pepine CJ, Pettinger M, Price TS, Rafelt S, Ranchalis J, Rasheed A, Rosenthal E, Ruczinski I, Shah S, Shen H, Silbernagel G, Smith EN, Spijkerman AW, Stanton A, Steffes MW, Thorand B, Trip M, van der Harst P, van der A DL, van Iperen EP, van Setten J, van Vliet-Ostaptchouk JV, Verweij N, Wolffenbuttel BH, Young T, Zafarmand MH, Zmuda JM; Look AHEAD Research Group; DIAGRAM consortium, Boehnke M, Altshuler D, McCarthy M, Kao WH, Pankow JS, Cappola TP, Sever P, Poulter N, Caulfield M, Dominiczak A, Shields DC, Bhatt DL, Zhang L, Curtis SP, Danesh J, Casas JP, van der Schouw YT, Onland-Moret NC, Doevendans PA, Dorn GW 2nd, Farrall M, FitzGerald GA, Hamsten A, Hegele R, Hingorani AD, Hofker MH, Huggins GS, Illig T, Jarvik GP, Johnson JA, Klungel OH, Knowler WC, Koenig W, März W, Meigs JB, Melander O, Munroe PB, Mitchell BD, Bielinski SJ, Rader DJ, Reilly MP, Rich SS, Rotter JI, Saleheen D, Samani NJ, Schadt EE, Shuldiner AR, Silverstein R, Kottke-Marchant K, Talmud PJ, Watkins H, Asselbergs FW, de Bakker PI, McCaffery J, Wijmenga C, Sabatine MS, Wilson JG, Reiner A, Bowden DW, Hakonarson H, Siscovick DS, Keating BJ. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet 2012;90:410-425

1820  Schaefer MH, Fontaine JF, Vinayagam A, Porras P, Wanker EE, Andrade-Navarro MA.  HIPPIE: Integrating protein interaction networks with experiment based quality scores.  PLoS One. 2012;7(2):e31826.

1819  Schaefer MH, Wanker EE, Andrade-Navarro MA.  Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks.  Nucleic Acids Res. 2012 Jan 28.

1818 Schell H, Boden C, Chagas AM, Kahle PJ.  Impaired c-Fos and polo-like kinase 2 induction in the limbic system of fear-conditioned ?-synuclein transgenic mice.  PLoS One. 2012;7(11):e50245.

1817 Schiemann J, Schlaudraff F, Klose V, Bingmer M, Seino S, Magill PJ, Zaghloul KA, Schneider G, Liss B, Roeper J.  K-ATP channels in dopamine substantia nigra neurons control bursting and novelty-induced exploration.  Nature Neuroscience. 2012 Aug 19. doi:10.1038/nn.3185.

1816 Schiesser S, Hackner B, Pfaffeneder T, Müller M, Hagemeier C, Truss M, Carell T.  Mechanism and Stem-Cell Activity of 5-Carboxycytosine Decarboxylation Determined by Isotope Tracing.  Angew Chem Int Ed Engl. 2012 Jun 25;51(26):6516-20. doi: 10.1002/anie.201202583. Epub 2012 May 29.

1815 Schildhaus HU, Heukamp LC, Merkelbach-Bruse S, Riesner K, Schmitz K, Binot E, Paggen E, Albus K, Schulte W, Ko YD, Schlesinger A, Ansén S, Engel-Riedel W, Brockmann M, Serke M, Gerigk U, Huss S, Goke F, Perner S, Hekmat K, Frank KF, Reiser M, Schnell R, Bos M, Mattonet C, Sos M, Stoelben E, Wolf J, Zander T, Buettner R. Definition of a fluorescence in-situ hybridization score identifies high- and low-level fgfr1 amplification types in squamous cell lung cancer.  Mod Pathol 2012;25:1473-1480

1814 Schirwitz, C., Löffler, F., Felgenhauer, T., Stadler, V., Breitling, F. & Bischoff, F.R.  Sensing immune responses with customized peptide microarrays. Biointerphases 7,47.

1813  Schleiermacher G, Mosseri V, London WB, Maris JM, Brodeur GM, Attiyeh E, Haber M, Khan J, Nakagawara A, Speleman F, Noguera R, Tonini GP, Fischer M, Ambros I, Monclair T, Matthay KK, Ambros P, Cohn SL, Pearson ADJ. Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project.  Br J Cancer, 2012, 107(8): 1418-1422.

1812 Schmid MW, Schmidt A, Klostermeier UC, Barann M, Rosenstiel P, Grossniklaus U.  A powerful method for transcriptional profiling of specific cell types in eukaryotes: laser-assisted microdissection and RNA sequencing.  PLoS One. 2012;7(1):e29685. Epub 2012 Jan 26.

1811 Schmidt M, Hellwig B, Hammad S, Othman A, Lohr M, Chen Z, Boehm D, Gebhard S, Petry I, Lebrecht A, Cadenas C, Marchan R, Stewart JD, Solbach C, Holmberg L,Edlund K, Kultima HG, Rody A, Berglund A, Lambe M, Isaksson A, Botling J, Karn T,Müller V, Gerhold-Ay A, Cotarelo C, Sebastian M, Kronenwett R, Bojar H, Lehr HA, Sahin U, Koelbl H, Gehrmann M, Micke P, Rahnenführer J, Hengstler JG.  A Comprehensive Analysis of Human Gene Expression Profiles Identifies StromalImmunoglobulin ? C as a Compatible Prognostic Marker in Human Solid Tumors.  Clin Cancer Res. 2012 May;18(9):2695-2703.

1810 Schneider, R., C. Becker, J.R. Simard, M. Getlik, N. Bohlke, P. Janning, D. Rauh. Direct Binding Assay for the Detection of Type IV Allosteric Inhibitors of Abl.  J Am Chem Soc, 2012, 134(22):9138-41.

1809 Scholz B, Marschalek R Epigenetics and blood disorders.  Br J Haematol 158, 307-322.

1808 Schonig, K., Weber, T., Frommig, A., Wendler, L., Pesold, B., Djandji, D., Bujard, H., and Bartsch, D.  Conditional Gene Expression Systems in the Transgenic Rat Brain.  BMC Biol 10, 77.

1807 Schreiber S, Reinisch W, Colombel JF, Sandborn WJ, Hommes DW, Robinson AM, Huang B, Lomax KG, Pollack PF. Subgroup analysis of the placebo-controlled CHARM trial: increased remission rates through 3 years for adalimumab-treated patients with early Crohn's disease.<http://www.ncbi.nlm.nih.gov/pubmed/22704916> J Crohns Colitis. 2013 Apr 1;7(3):213-21. doi: 10.1016/j.crohns.2012.05.015. Epub 2012 Jun 16.

1806 Schubert J, Paravidino R, Becker F, Berger A, Bebek N, Bianchi A, Brockmann K, Capovilla G, Dalla Bernardina B, Fukuyama Y, Hoffmann GF, Jurkat-Rott K, Antonnen A, Kurlemann G, Lehesjoki AE, Lehmann-Horn F, Mastrangelo M, Mause U, Müller S, Neubauer B, Püst B, Rating D, Robbiano A, Ruf S, Schroeder C, Seidel A, Specchio N, Stephani U, Striano P, Teichler J, Turkdogan D, Vigevano F, Viri M, Bauer P, Zara F, Lerche H, Weber YG.  PRRT2 mutations are the major cause of benign familial infantile seizures (BFIS).  Hum Mutat. 2012;33:1439-43.

1805 Schubert W, Gieseler A, Krusche A, Serocka P, Hillert R Next-generation biomarkers based on 100-parameter functional super-resolution microscopy TIS.  N Biotechnol. 2012 Jun 15;29(5):599-610. doi: 10.1016/j.nbt.2011.12.004.

1804 Schuchardt M, Tölle M, Prüfer J, Prüfer N, Huang T, Jankowski V, Jankowski J, Zidek W, van der Giet M. Uridine adenosine tetraphosphate activation of the purinergic receptor P2Y enhances in vitro vascular calcification. Kidney Int. 2012 Feb;81(3):256-65 

1803 Schuhmacher A, Becker T, Rujescu D, Quednow BB, Lennertz L, Wagner M, Benninghoff J, Rietschel M, Häfner H, Franke P, Wölwer W, Gaebel W, Maier W, Mössner R.  Investigation of tryptophan hydroxylase 2 (TPH2) in schizophrenia and in the response to antipsychotics.  J Psychiatr Res. 2012 Aug;46(8):1073-80. doi: 10.1016/j.jpsychires.2012.04.021.

1802 Schuhmacher A, Lennertz L, Wagner M, Höfels S, Pfeiffer U, Guttenthaler V, Maier W, Zobel A, Mössner R. A variant of the neuronal amino acid transporter SLC6A15 is associated with ACTH and cortisol responses and cognitive performance in unipolar depression. Int J Neuropsychopharmacol. 2012 Apr 4:1-8. [Epub ahead of print] ( im Druck)PMID: 22475622.

1801 Schulze TG, Akula N, Breuer R, Steele J, Nalls MA, Singleton AB, Degenhardt FA, Nöthen MM, Cichon S, Rietschel M; The Bipolar Genome Study, McMahon FJ.  Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder.  World J Biol Psychiatry. 2012 Mar 9. doi:10.3109/15622975.2012.662282.

1800 Schurmann C, Heim K, Schillert A, Blankenberg S, Carstensen M, Dörr M, Endlich K, Felix SB, Gieger C, Grallert H, Herder C, Hoffmann W, Homuth G, Illig T, Kruppa J, Meitinger T, Müller C, Nauck M, Peters A, Rettig R, Roden M, Strauch K, Völker U, Völzke H, Wahl S, Wallaschofski H, Wild PS, Zeller T, Teumer A, Prokisch H, Ziegler A. Analyzing illumina gene expression microarray data from different tissues: methodological aspects of data analysis in the metaxpress consortium. PLoS One. 2012;7(12):e50938

1799 Schuster C, Malinowsky K, Liebmann S, Berg D, Wolff C, Tran K, Schott C, ReuS, Neumann J, Faber C, Höfler H, Kirchner T, Becker KF, Hlubek F.   Antibodyvalidation by combining immunohistochemistry and protein extraction fromformalin-fixed paraffin-embedded tissues. Histopathology. 2012May;60(6B):E37-E50. doi: 10.1111/j.1365-2559.2012.04184.

1798 Schwartzentruber J, Korshunov A, Liu XY, Jones DT, Pfaff E, Jacob K, Sturm D, Fontebasso AM, Quang DA, Tönjes M, Hovestadt V, Albrecht S, Kool M, Nantel A, Konermann C, Lindroth A, Jäger N, Rausch T, Ryzhova M, Korbel JO, Hielscher T, Hauser P, Garami M, Klekner A, Bognar L, Ebinger M, Schuhmann MU, Scheurlen W, Pekrun A, Frühwald MC, Roggendorf W, Kramm C, Dürken M, Atkinson J, Lepage P, Montpetit A, Zakrzewska M, Zakrzewski K, Liberski PP, Dong Z, Siegel P, Kulozik AE, Zapatka M, Guha A, Malkin D, Felsberg J, Reifenberger G, von Deimling A, Ichimura K, Collins VP, Witt H, Milde T, Witt O, Zhang C, Castelo-Branco P, Lichter P, Faury D, Tabori U, Plass C, Majewski J, Pfister SM, Jabado N.  Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma.  Nature. 2012 Jan 29;482(7384):226-31.

1797 Scott RA, Lagou V, Welch RP, Wheeler E, Montasser ME, Luan J, Mägi R, Strawbridge RJ, Rehnberg E, Gustafsson S, Kanoni S, Rasmussen-Torvik LJ, Yengo L, Lecoeur C, Shungin D, Sanna S, Sidore C, Johnson PC, Jukema JW, Johnson T, Mahajan A, Verweij N, Thorleifsson G, Hottenga JJ, Shah S, Smith AV, Sennblad B, Gieger C, Salo P, Perola M, Timpson NJ, Evans DM, Pourcain BS, Wu Y, Andrews JS, Hui J, Bielak LF, Zhao W, Horikoshi M, Navarro P, Isaacs A, O'Connell JR, Stirrups K, Vitart V, Hayward C, Esko T, Mihailov E, Fraser RM, Fall T, Voight BF, Raychaudhuri S, Chen H, Lindgren CM, Morris AP, Rayner NW, Robertson N, Rybin D, Liu CT, Beckmann JS, Willems SM, Chines PS, Jackson AU, Kang HM, Stringham HM, Song K, Tanaka T, Peden JF, Goel A, Hicks AA, An P, Müller-Nurasyid M, Franco-Cereceda A, Folkersen L, Marullo L, Jansen H, Oldehinkel AJ, Bruinenberg M, Pankow JS, North KE, Forouhi NG, Loos RJ, Edkins S, Varga TV, Hallmans G, Oksa H, Antonella M, Nagaraja R, Trompet S, Ford I, Bakker SJ, Kong A, Kumari M, Gigante B, Herder C, Munroe PB, Caulfield M, Antti J, Mangino M, Small K, Miljkovic I, Liu Y, Atalay M, Kiess W, James AL, Rivadeneira F, Uitterlinden AG, Palmer CN, Doney AS, Willemsen G, Smit JH, Campbell S, Polasek O, Bonnycastle LL, Hercberg S, Dimitriou M, Bolton JL, Fowkes GR, Kovacs P, Lindström J, Zemunik T, Bandinelli S, Wild SH, Basart HV, Rathmann W, Grallert H; DIAbetes Genetics Replication and Meta-analysis (DIAGRAM) Consortium, Maerz W, Kleber ME, Boehm BO, Peters A, Pramstaller PP, Province MA, Borecki IB, Hastie ND, Rudan I, Campbell H, Watkins H, Farrall M, Stumvoll M, Ferrucci L, Waterworth DM, Bergman RN, Collins FS, Tuomilehto J, Watanabe RM, de Geus EJ, Penninx BW, Hofman A, Oostra BA, Psaty BM, Vollenweider P, Wilson JF, Wright AF, Hovingh GK, Metspalu A, Uusitupa M, Magnusson PK, Kyvik KO, Kaprio J, Price JF, Dedoussis GV, Deloukas P, Meneton P, Lind L, Boehnke M, Shuldiner AR, van Duijn CM, Morris AD, Toenjes A, Peyser PA, Beilby JP, Körner A, Kuusisto J, Laakso M, Bornstein SR, Schwarz PE, Lakka TA, Rauramaa R, Adair LS, Smith GD, Spector TD, Illig T, de Faire U, Hamsten A, Gudnason V, Kivimaki M, Hingorani A, Keinanen-Kiukaanniemi SM, Saaristo TE, Boomsma DI, Stefansson K, van der Harst P, Dupuis J, Pedersen NL, Sattar N, Harris TB, Cucca F, Ripatti S, Salomaa V, Mohlke KL, Balkau B, Froguel P, Pouta A, Jarvelin MR, Wareham NJ, Bouatia-Naji N, McCarthy MI, Franks PW, Meigs JB, Teslovich TM, Florez JC, Langenberg C, Ingelsson E, Prokopenko I, Barroso I Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.  Nat Genet. 2012 Sep;44(9):991-1005. doi: 10.1038/ng.2385. Epub 2012 Aug 12. 

1796 Shamu C, Wiemann S, Boutros M.  On target: A public repository for large-scale RNAi experiments. Nat Cell Biology 14: 115.

1795 Sharma M,  Krüger R, Gasser T. LRRK2: Understanding the role of common and rare variants in Parkinson disease.  Mov Disord 20: 475.

1794 Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Bertram L, Bozi M, Barcikowska M, Crosiers D, Clarke CE, Facheris MF, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon BS, Jamrozik Z, Krygowska-Wajs A, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Libioulle C, Murata M, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Meitnger T, Zimprich A, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Strom TM, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Van Broeckhoven C, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yomono HS, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R; GEOPD consortium. A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants. J Med Genet 49: 721-726.

1793 Sharma M, Ioannidis JP, Aasly JO, Annesi G, Brice A, Van Broeckhoven C, Bertram L, Bozi M, Crosiers D, Clarke C, Facheris M, Farrer M, Garraux G, Gispert S, Auburger G, Vilariño-Güell C, Hadjigeorgiou GM, Hicks AA, Hattori N, Jeon B, Lesage S, Lill CM, Lin JJ, Lynch T, Lichtner P, Lang AE, Mok V, Jasinska-Myga B, Mellick GD, Morrison KE, Opala G, Pramstaller PP, Pichler I, Park SS, Quattrone A, Rogaeva E, Ross OA, Stefanis L, Stockton JD, Satake W, Silburn PA, Theuns J, Tan EK, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Yueh KC, Zhao Y, Gasser T, Maraganore D, Krüger R; GEO-PD Consortium. Large-scale replication and heterogeneity in Parkinson disease genetic loci. Neurology. 2012 Aug 14;79(7):659-67.

1792 Shymanets A, Ahmadian MR, Koessmeier KT, Wetzker R, Harteneck C, Nürnberg B. The p101 subunit of PI3K? restores activation by G? mutants deficient in stimulating p110?. Biochem J 441, 851-858. PMID: 22054284.

1791 Siggelkow W, Boehm D, Gebhard S, Battista M, Sicking I, Lebrecht A, Solbach C,Hellwig B, Rahnenführer J, Koelbl H, Gehrmann M, Marchan R, Cadenas C, Hengstler JG, Schmidt M.  Expression of aurora kinase A is associated with metastasis-freesurvival in node-negative breast cancer patients.  BMC Cancer. 2012 Nov 27;12:562.doi: 10.1186/1471-2407-12-562.

1790 Simard, J.R, D. Rauh. Fluorescence labels in kinases: a high-throughput kinase binding assay for the identification of DFG-out binding ligands. Methods Mol Biol, 2012;800:95-117.

1789 Simón-Sánchez J, Kilarski LL, Nalls MA, Martinez M, Schulte C, Holmans P; International Parkinson's Disease Genomics Consortium; Wellcome Trust Case Control Consortium, Gasser T, Hardy J, Singleton AB, Wood NW, Brice A, Heutink P, Williams N, Morris HR.  Cooperative genome-wide analysis shows increased homozygosity in early onset Parkinson's disease.  PLoS One. 2012;7(3):e28787. doi: 10.1371/journal.pone.0028787.

1788 Simpson JC, Joggerst B, Laketa V, Verissimo F, Cetin C, Erfle H, Bexiga MG, Singan VR, Heriche JK, Neumann B et al:  Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway.  Nat Cell Biol 2012, 14(7):764-774.

1787 Sina C, Lipinski S, Gavrilova O, Aden K, Rehman A, Till A, Rittger A, PodschunR, Meyer-Hoffert U, Haesler R, Midtling E, Pütsep K, McGuckin MA, Schreiber S,Saftig P, Rosenstiel P.  Extracellular cathepsin K exerts antimicrobial activityand is protective against chronic intestinal inflammation in mice.  Gut. 2012 Mar 22. [Epub ahead of print] PubMed PMID: 22442160.

1786 Siveke JT, Crawford HC.  Kras above and beyond - EGFR in pancreatic cancer.  Oncotarget 2012; Nov;3(11):1262-3. 

1785 Slotta-Huspenina J, Berg D, Bauer K, Wolff C, Malinowsky K, Bauer L, Drecoll E, Bettstetter M, Feith M, Walch A, Höfler H, Becker KF, Langer R. Evidence of prognostic relevant expression profiles of heat-shock proteins and glucose-regulated proteins in oesophageal adenocarcinomas. PLoS One. 2012;7(7):e41420. doi: 10.1371/journal.pone.0041420.

1784 Sommer AP, Bieschke J, Friedrich RP, Zhu D, Wanker EE, Fecht HJ, Mereles D, Hunstein W.  670?nm laser light and EGCG complementarily reduce amyloid-? aggregates in human neuroblastoma cells: basis for treatment of Alzheimer's disease? Photomed Laser Surg. 2012 Jan;30(1):54-60. Epub 2011 Oct 26.

1783 Spaich S, Will RD, Just S, Spaich S, Kuhn C, Frank D, Berger IM, Wiemann S, Korn B, Koegl M et al:  F-box and leucine-rich repeat protein 22 is a cardiac-enriched F-box protein that regulates sarcomeric protein turnover and is essential for maintenance of contractile function in vivo.  Circ Res 2012, 111(12):1504-1516.

1782 Spanagel R, Vengeliene V.  New Pharmacological Treatment Strategies for Relapse Prevention.  Curr Top Behav Neurosci. 2013;13:583-609.

1781 Spehlmann ME, Begun AZ, Saroglou E, Hinrichs F, Tiemann U, Raedler A, Schreiber S.  Risk factors in German twins with inflammatory bowel disease: results of a questionnaire-based survey.  J Crohns Colitis. 2012 Feb;6(1):29-42.

1780 Sperveslage J, Frank S, Heneweer C, Egberts J, Schniewind B, Buchholz M,Bergmann F, Giese N, Munding J, Hahn SA, Kalthoff H, Klöppel G, Sipos B.  Lack of CCR7 expression is rate limiting for lymphatic spread of pancreatic ductal adenocarcinoma.  Int J Cancer. 2012, 131:E371-381

1779 Spomer W, Pfriem A, Alshut R, Just S, Pylatiuk C.  High-throughput screening of zebrafish embryos using automated heart detection and imaging.  Journal of laboratory automation 2012 17:435-442..

1778 Spyroglou A, Sabrautzki S, Rathkolb B, Bozoglu T, Hrabé de Angelis M, Reincke M, Bidlingmaier M, Beuschlein F.  Gender-, strain-, and inheritance-dependent variation in aldosterone secretion in mice.  J Endocrinol. 2012 Dec;215(3):375-81. doi: 10.1530/JOE-12-0429.

1777 Srivastava B, Mells GF, Cordell HJ, Muriithi A, Brown M, Ellinghaus E, Franke A, Consortium UP, Karlsen TH, Sandford RN, Alexander GJ, Chapman RW, Rushbrook SM, Melum E.  Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis.  Scand J Gastroenterol. 2012 Jul;47(7):820-6. doi: 10.3109/00365521.2012.682090. Epub 2012 May 4. PMID: 22554193.

1776 Stacey D, Bilbao A, Maroteaux M, Jia T, Easton AC, Longueville S, Nymberg C, Banaschewski T, Barker GJ, Büchel C, Carvalho F, Conrod PJ, Desrivières S, Fauth-Bühler M, Fernandez-Medarde A, Flor H, Gallinat J, Garavan H, Bokde AL, Heinz A, Ittermann B, Lathrop M, Lawrence C, Loth E, Lourdusamy A, Mann KF, Martinot JL, Nees F, Palkovits M, Paus T, Pausova Z, Rietschel M, Ruggeri B, Santos E, Smolka MN, Staehlin O, Jarvelin MR, Elliott P, Sommer WH, Mameli M, Müller CP, Spanagel R, Girault JA, Schumann G; IMAGEN Consortium.  RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release.  Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21128-33.

1775 Stäehler CF, Keller A, Leidinger P, Backes C, Chandran A, Wischhusen J, Meder B, Meese E.  Whole miRNome-wide Differential Co-expression of MicroRNAs.  Genomics Proteomics Bioinformatics. 2012 Oct;10(5):285-94. doi: 10.1016/j.gpb.2012.08.003. Epub 2012 Aug 23.

1774 Staropoli JF, Haliw L, Biswas S, Garrett L, Hölter SM, Becker L, Skosyrski S, Da Silva-Buttkus P, Calzada-Wack J, Neff F, Rathkolb B, Rozman J, Schrewe A, Adler T, Puk O, Sun M, Favor J, Racz I, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Wolf E, Wurst W, Zimmer A, Lopez E, Harati H, Hill E, Krause DS, Guide J, Dragileva E, Gale E, Wheeler VC, Boustany RM, Brown DE, Breton S, Ruether K, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Cotman SL:  Large-scale phenotyping of an accurate genetic mouse model of JNCL identifies novel early pathology outside the central nervous system.  PLoS ONE. 7(6), e38310 (2012) doi:10.1371/journal.pone.0038310.

1773 Steenweg ME, Ghezzi D, Haack T, Abbink TE, Martinelli D, van Berkel CG, Bley A, Diogo L,
Grillo E, Te Water Naudé J, Strom TM, Bertini E, Prokisch H, van der Knaap MS, Zeviani M.  Leukoencephalopathy with thalamus and brainstem involvement and high lactate 'LTBL' caused by EARS2 mutations.  Brain. 2012 Apr 4. [Epub ahead of print] PubMed PMID: 22492562.

1772 Stefan T. Börno, Axel Fischer, Martin Kerick, Maria Fälth, Mark Laible, Jan C. Brase, Ruprecht Kuner, Andreas Dahl, Christina Grimm, Melanie Isau, Christina Röhr, Andrea Wunderlich, Bernd Timmermann, Rainer Claus, Christoph Plass, Markus Graefen, Ronald Simon, Francesca Demichelis, Mark A. Rubin, Guido Sauter, Thorsten Schlomm, Holger Sültmann, Hans Lehrach and Michal R. Schweiger. Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discov. 2012 Nov;2(11):1024-35. doi: 10.1158/2159-8290.CD-12-0041. Epub 2012 Aug 28.

1771 Stein C, Kling L, Proetzel G, Roopenian DC, Hrabé de Angelis M, Wolf E, Rathkolb B:  Clinical chemistry of human FcRn transgenic mice.  Mamm Genome 23, 259-269 (2012) DOI 10.1007/s00335-011-9379-6.

1770 Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM,  Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth  E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH,  Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW,  Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería  ME, Rietschel M, Roffman JL, Royle NA, Rujescu D, Savitz J, Schnack HG, Schnell K, Seiferth N, Smith C, Steen VM, Valdés Hernández MC, Van den Heuvel M, van der  Wee NJ, Van Haren NE, Veltman JA, Völzke H, Walker R, Westlye LT, Whelan CD, Agartz I, Boomsma DI, Cavalleri GL, Dale AM, Djurovic S, Drevets WC, Hagoort P, Hall J, Heinz A, Jack CR Jr, Foroud TM, Le Hellard S, Macciardi F, Montgomery GW, Poline JB, Porteous DJ, Sisodiya SM, Starr JM, Sussmann J, Toga AW, Veltman DJ, Walter H, Weiner MW; Alzheimer's Disease Neuroimaging Initiative; EPIGEN Consortium; IMAGEN Consortium; Saguenay Youth Study Group, Bis JC, Ikram MA, Smith AV, Gudnason V, Tzourio C, Vernooij MW, Launer LJ, DeCarli C, Seshadri S; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium, Andreassen OA, Apostolova LG, Bastin ME, Blangero J, Brunner HG, Buckner RL, Cichon S, Coppola G, de Zubicaray GI, Deary IJ, Donohoe G, de Geus EJ, Espeseth T, Fernández G, Glahn DC, Grabe HJ, Hardy J, Hulshoff Pol HE, Jenkinson M, Kahn RS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Meyer-Lindenberg A, Morris DW, Müller-Myhsok B, Nichols TE, Ophoff RA, Paus T, Pausova Z, Penninx BW, Potkin SG, Sämann PG, Saykin AJ, Schumann G, Smoller JW, Wardlaw JM, Weale ME, Martin NG, Franke B, Wright MJ, Thompson PM; Identification of common variants associated with human hippocampal and intracranial volumes.  Nat Genet. 2012 Apr 15;44(5):552-61.

1769 Steinberg S, de Jong S, Mattheisen M, Costas J, Demontis D, Jamain S, Pietiläinen OP, Lin K, Papiol S, Huttenlocher J, Sigurdsson E, Vassos E, Giegling I, Breuer R, Fraser G, Walker N, Melle I, Djurovic S, Agartz I, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Olsen L, Hansen T, Ingason A, Pirinen M, Strengman E; GROUP, Hougaard DM, Orntoft T, Didriksen M, Hollegaard MV, Nordentoft M, Abramova L, Kaleda V, Arrojo M, Sanjuán J, Arango C, Etain B, Bellivier F, Méary A, Schürhoff F, Szoke A, Ribolsi M, Magni V, Siracusano A, Sperling S, Rossner M, Christiansen C, Kiemeney LA, Franke B, van den Berg LH, Veldink J, Curran S, Bolton P, Poot M, Staal W, Rehnstrom K, Kilpinen H, Freitag CM, Meyer J, Magnusson P, Saemundsen E, Martsenkovsky I, Bikshaieva I, Martsenkovska I, Vashchenko O, Raleva M, Paketchieva K, Stefanovski B, Durmishi N, Pejovic Milovancevic M, Lecic Tosevski D, Silagadze T, Naneishvili N, Mikeladze N, Surguladze S, Vincent JB, Farmer A, Mitchell PB, Wright A, Schofield PR, Fullerton JM, Montgomery GW, Martin NG, Rubino IA, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Terenius L, Jönsson EG, Bakker S, van Os J, Jablensky A, Leboyer M, Bramon E, Powell J, Murray R, Corvin A, Gill M, Morris D, O'Neill FA, Kendler K, Riley B; Wellcome Trust Case Control Consortium 2, Craddock N, Owen MJ, O'Donovan MC, Thorsteinsdottir U, Kong A, Ehrenreich H, Carracedo A, Golimbet V, Andreassen OA, Børglum AD, Mors O, Mortensen PB, Werge T, Ophoff RA, Nöthen MM, Rietschel M, Cichon S, Ruggeri M, Tosato S, Palotie A, St Clair D, Rujescu D, Collier DA, Stefansson H, Stefansson K.  Common variant at 16p11.2 conferring risk of psychosis.  Mol Psychiatry. 2012 Nov 20. doi: 10.1038/mp.2012.157.

1768 Stigliani, S., S. Coco, S. Moretti, A. Oberthuer, M. Fischer, J. Theissen, F. Gallo, A. Garavent, F. Berthold, S. Bonassi, G.P. Tonini, and P. Scaruffi High genomic instability predicts survival in metastatic high-risk neuroblastoma.  Neoplasia, 2012. 14(9): p. 823-32.

1767 Stingl JC, Esslinger C, Tost H, Bilek E, Kirsch P, Ohmle B, Viviani R, Walter H, Rietschel M, Meyer-Lindenberg A.  Genetic variation in CYP2D6 impacts neural activation during cognitive tasks in humans.  Neuroimage 59(3):2818-23..

1766 Strawbridge RJ, Dupuis J, Prokopenko I, Barker A, Ahlqvist E, Rybin D, Petrie JR, Travers ME, Bouatia-Naji N, Dimas AS, Nica A, Wheeler E, Chen H, Voight BF, Taneera J, Kanoni S, Peden JF, Turrini F, Gustafsson S, Zabena C, Almgren P, Barker DJ, Barnes D, Dennison EM, Eriksson JG, Eriksson P, Eury E, Folkersen L, Fox CS, Frayling TM, Goel A, Gu HF, Horikoshi M, Isomaa B, Jackson AU, Jameson KA, Kajantie E, Kerr-Conte J, Kuulasmaa T, Kuusisto J, Loos RJ, Luan J, Makrilakis K, Manning AK, Martínez-Larrad MT, Narisu N, Nastase Mannila M, Ohrvik J, Osmond C, Pascoe L, Payne F, Sayer AA, Sennblad B, Silveira A, Stancáková A, Stirrups K, Swift AJ, Syvänen AC, Tuomi T, van 't Hooft FM, Walker M, Weedon MN, Xie W, Zethelius B; DIAGRAM Consortium; GIANT Consortium; MuTHER Consortium; CARDIoGRAM Consortium; C4D Consortium, Ongen H, Mälarstig A, Hopewell JC, Saleheen D, Chambers J, Parish S, Danesh J, Kooner J, Ostenson CG, Lind L, Cooper CC, Serrano-Ríos M, Ferrannini E, Forsen TJ, Clarke R, Franzosi MG, Seedorf U, Watkins H, Froguel P, Johnson P, Deloukas P, Collins FS, Laakso M, Dermitzakis ET, Boehnke M, McCarthy MI, Wareham NJ, Groop L, Pattou F, Gloyn AL, Dedoussis GV, Lyssenko V, Meigs JB, Barroso I, Watanabe RM, Ingelsson E, Langenberg C, Hamsten A, Florez JC. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 2011 Oct;60(10):2624-34. doi: 10.2337/db11-0415. Epub 2011 Aug 26.

1765 Streckfuss-Bömeke K, Wolf F, Azizian A, Stauske M, Tiburcy M, Wagner S, Hübscher D, Dressel R, Chen S, Jende J, Wulf G, Lorenz V, Schön MP, Maier LS, Zimmermann WH, Hasenfuss G, Guan K.  Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts. (2012)  Eur Heart J,  doi:10.1093/eurheartj/ehs203 [Epub ahead of print].

1764 Striano P, Weber YG, Toliat MR, Schubert J, Leu C, Chaimana R, Baulac S, Guerrero R, LeGuern E, Lehesjoki AE, Polvi A, Robbiano A, Serratosa JM, Guerrini R, Nürnberg P, Sander T, Zara F, Lerche H, Marini C; EPICURE Consortium.  GLUT1 mutations are a rare cause of familial idiopathic generalized epilepsy.  Neurology. 2012 Feb 21;78(8):557-62. Epub 2012 Jan 25. PMID: 22282645 [PubMed - indexed for MEDLINE].

1763 Sturm D, Witt H, Hovestadt V, Khuong-Quang DA, Jones DT, Konermann C, Pfaff E, Tönjes M, Sill M, Bender S, Kool M, Zapatka M, Becker N, Zucknick M, Hielscher T, Liu XY, Fontebasso AM, Ryzhova M, Albrecht S, Jacob K, Wolter M, Ebinger M, Schuhmann MU, van Meter T, Frühwald MC, Hauch H, Pekrun A, Radlwimmer B, Niehues T, von Komorowski G, Dürken M, Kulozik AE, Madden J, Donson A, Foreman NK, Drissi R, Fouladi M, Scheurlen W, von Deimling A, Monoranu C, Roggendorf W, Herold-Mende C, Unterberg A, Kramm CM, Felsberg J, Hartmann C, Wiestler B, Wick W, Milde T, Witt O, Lindroth AM, Schwartzentruber J, Faury D, Fleming A, Zakrzewska M, Liberski PP, Zakrzewski K, Hauser P, Garami M, Klekner A, Bognar L, Morrissy S, Cavalli F, Taylor MD, van Sluis P, Koster J, Versteeg R, Volckmann R, Mikkelsen T, Aldape K, Reifenberger G, Collins VP, Majewski J, Korshunov A, Lichter P, Plass C, Jabado N, Pfister SM.  Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.  Cancer Cell. 2012 Oct 16;22(4):425-37. doi: 10.1016/j.ccr.2012.08.024.

1762 Sullivan P; 96 Psychiatric Genetics Investigators. Don't give up on GWAS.  Mol Psychiatry. 2012 Jan;17(1):2-3. doi: 10.1038/mp.2011.94. Epub 2011 Aug 9.

1761 Suter B and Wanker EE. The investigation of binary PPIs with the classical yeast two-hybrid (Y2H) approach, Y2H variants, and other in vivo methods for PPI mapping. Methods Mol Biol. 2012;812:v-vi.

1760 Swierczek M, Izsvák Z, Ivics Z The Sleeping Beauty transposon system for clinical applications. Expert Opin Biol Ther. 2012 Feb;12(2):139-53. doi: 10.1517/14712598.2012.642358. PMID:22176302.

1759 Szymczak S, Scheinhardt MO, Zeller T, Wild PS, Blankenberg S, Ziegler A. Adaptive linear rank tests for eQTL studies. Stat Med. 2013 Feb 10;32(3):524-37

1758 Tagscherer KE, Fassl A, Sinkovic T, Combs SE, Roth W.  p53-dependent regulation of Mcl-1 contributes to synergistic cell death by ionizing radiation and the Bcl-2/Bcl-XL inhibitor ABT-737.  Apoptosis. 2012 Feb; 17(2):187-199. doi 10.1007/s10495-011-0664-3.

1757 Taschenberger G, Garrido M, Tereshchenko Y, Bähr M, Zweckstetter M, Kügler S. Aggregation of ?Synuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons. Acta Neuropathol. 2012 May;123(5):671-83.

1756 Taudien S, Gäbel G, Kuss O, Groth M, Grützmann R, Huse K, Kluttig A, Wolf A, Nothnagel M, Rosenstiel P, Greiser KH, Werdan K, Krawczak M, Pilarsky C, Platzer M. Association studies of the copy-number variable ß-defensin cluster on 8p23.1 in adenocarcinoma and chronic pancreatitis.  BMC Res Notes. 2012 Nov 13;5:629.

1755 Terwisscha van Scheltinga AF, Bakker SC, van Haren NE, Derks EM, Buizer-Voskamp JE, Boos HB, Cahn W, Hulshoff Pol HE, Ripke S, Ophoff RA, Kahn RS; Psychiatric Genome-wide Association Study Consortium.  Genetic schizophrenia risk variants jointly modulate total brain and white matter volume.  Biol Psychiatry. 2013 Mar 15;73(6):525-31. doi: 10.1016/j.biopsych.2012.08.017.

1754 Thiele F, Cohrs CM, Flor A, Lisse TS, Przemeck GK, Horsch M, Schrewe A, Gailus-Durner V, Ivandic B, Katus HA, Wurst W, Reisenberg C, Chaney H, Fuchs H, Hans W, Beckers J, Marini JC, Hrabé de Angelis M:  Cardiopulmonary dysfunction in the Osteogenesis imperfecta mouse model Aga2 and human patients are caused by bone-independent mechanisms.  Hum Mol Genet. 21(16):3535-45 (2012) doi:10.1093/hmg/dds183.

1753 Thier S, Lorenz D, Nothnagel M, Poremba C, Papengut F, Appenzeller S, Paschen S, Hofschulte F, Hussl AC, Hering S, Poewe W, Asmus F, Gasser T, Schöls L, Christensen K, Nebel A, Schreiber S, Klebe S, Deuschl G, Kuhlenbäumer G.  Polymorphisms in the glial glutamate transporter SLC1A2 are associated with essential tremor.  Neurology. 2012 Jul 17;79(3):243-8.

1752 Thomas R, Wolf J: Personalized therapy of lung cancer. Onkologie 2012;35 Suppl 1:14-19.

1751 Thye T, Owusu-Dabo E, Vannberg FO, van Crevel R, Curtis J, Sahiratmadja E, Balabanova Y, Ehmen C, Muntau B, Ruge G, Sievertsen J, Gyapong J, Nikolayevskyy V, Hill PC, Sirugo G, Drobniewski F, van de Vosse E, Newport M, Alisjahbana B, Nejentsev S, Ottenhoff TH, Hill AV, Horstmann RD, Meyer CG. Common variants at 11p13 are associated with susceptibility to tuberculosis. Nat Genet. 2012 Feb 5;44(3):257-9. doi: 10.1038/ng.1080.

1750 Thyssen JP, Thuesen B, Huth C, Standl M, Carson CG, Heinrich J, Krämer U, Kratzsch J, Berg ND, Menné T, Johansen JD, Carlsen BC, Schwab S, Thorand B, Munk M, Wallaschofski H, Heickendorff L, Meldgaard M, Szecsi PB, Stender S, Bønnelykke K, Weidinger S, Bisgaard H, Linneberg A.  Skin barrier abnormality caused by filaggrin (FLG) mutations is associated with increased serum 25-hydroxyvitamin D concentrations.  J Allergy Clin Immunol 2012; 130:1204-1207.e2.

1749 Timmann C et al.  Genome-wide association study indicates two novel resistance loci for severe malaria.  Nature. 2012 Sep 20;489(7416):443-6. doi: 10.1038/nature11334.

1748 Toncheva AA, Suttner K, Michel S, Klopp N, Illig T, Balschun T, Vogelberg C,von Berg A, Bufe A, Heinzmann A, Laub O, Rietschel E, Simma B, Frischer T,Genuneit J, von Mutius E, Kabesch M.  Genetic variants in Protocadherin-1,bronchial hyper-responsiveness, and asthma subphenotypes in German children. Pediatr Allergy Immunol. 2012 Nov;23(7):636-41. doi:10.1111/j.1399-3038.2012.01334.x. Epub 2012 Oct 11. PubMed PMID: 23050600.

1747 Tonini, G.P., A. Nakagawara, and F. Berthold. Towards a turning point of neuroblastoma therapy.  Cancer Lett, 2012. 326(2): p. 128-34.

1746 Treiber T, Treiber N. & Meister G. Regulation of microRNA biogenesis and function.  Thromb Haemost, 107(4):605-10.

1745 Tschäpe, J.-A. und Müller, UC.  Funktionen jenseits der Plaquebildung: die sekretierte Ektodomäne des Alzheimer-Schlüsselproteins APP ist essentiell für synaptische Plastizität, Lernen und Gedächtnis.  GenomXpress 1.12.

1744 Tsoi LC et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.  Nat Genet. 2012 Dec;44(12):1341-8. doi: 10.1038/ng.2467.

1743 Tuddenham L, Jung JS, Chane-Woon-Ming B, Dölken L, Pfeffer S. Small RNA deep sequencing identifies microRNAs and other small noncoding RNAs from human herpesvirus 6B. Journal of Virology Virol. 2012 Feb; 86(3):1638-49. Epub 2011 Nov 23.

1742 Tups A, Stöhr S, Helwig M, Barrett P, Krol E, Schachtner J, Mercer JG, Klingenspor M.  Seasonal leptin resistance is associated with impaired signalling via JAK2-STAT3 but not ERK, possibly mediated by reduced hypothalamic GRB2 protein.  J Comp Physiol B (2012) 182:553?567.

1741 Uhlmann S, Mannsperger H, Zhang JD, Horvat E-A, Schmidt C, Küblbeck M, Henjes F, Ward A, Tschulena U, Zweig K, Korf U, Wiemann S, Sahin O (2012)  Global microRNA level regulation of EGFR-driven cell cycle protein network in breast cancer.  Mol Syst Biol 8: 570.

1740 Uhlmann S, Mannsperger H, Zhang JD, Horvat E-A, Schmidt C, Küblbeck M, Henjes F, Ward A, Tschulena U, Zweig K, Korf U, Wiemann S, Sahin O.  Global microRNA level regulation of EGFR-driven cell cycle protein network in breast cancer.  Mol Syst Biol 8: 570.

1739 Ullrich RT, Zander T, Wolf J, Hallek M. Personalised treatment of lung cancer. Dtsch Med Wochenschr 2012;137:2179-2180.

1738 Ummanni R, Barreto F, Venz S, Scharf C, Barret C, Mannsperger HA, Brase JC, Kuner R, Schlomm T, Sauter G, Sültmann H, Korf U, Bokemeyer C, Walther R, Brümmendorf TH, Balabanov S.  Peroxiredoxins 3 and 4 are overexpressed in prostate cancer tissue and affect the proliferation of prostate cancer cells in vitro.  J Proteome Res. 2012

1737 Unsöld B, Schotola H, Jacobshagen C, Seidler T, Sossalla S, Emons J, Klede S, Knöll R, Guan K, El-Armouche A, Linke WA, Kögler H, Hasenfuss G.  Age-dependent changes in contractile function and passive elastic properties of myocardium from mice lacking muscle LIM protein (MLP). (2012)  European J Heart Fail, 14:430-437.

1736 van Buerck L, Schuster M, Rathkolb B, Sabrautzki S, Hrabé de Angelis M, Wolf E, Aigner B, Wanke R, Herbach N:  Enhanced oxidative stress and endocrine pancreas alterations are linked to a novel glucokinase missense mutation in ENU-derived Munich Gck(D217V) mutants.  Mol Cell Endocrinol. 2012 Oct 15;362(1-2):139-48. doi: 10.1016/j.mce.2012.06.001.

1735 van Loo KM, Schaub C, Pernhorst K, Yaari Y, Beck H, Schoch S, Becker AJ.  Transcriptional regulation of the T-type calcium channel CaV3.2: bi-directionality by early growth response 1 (Egr1) and RE1-silencing transcription factor (REST).  J Biol Chem. 2012 Mar 19. [Epub ahead of print]. PMID: 22431737.

1734 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.  Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium. Mol Syst Biol.  2012;8:571. PMID: 22373819.

1733 Vanmierlo T, Weingartner O, van der Pol S, Husche C, Kerksiek A, Friedrichs S, Sijbrands E, Steinbusch H, Grimm M, Hartmann T, Laufs U, Bohm M, de Vries HE, Mulder M, Lutjohann D. Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.  J Lipid Res. 2012 Apr;53(4):726-35. 

1732 Vassos E, Steinberg S, Cichon S, Breen G, Sigurdsson E, Andreassen OA, Djurovic S, Morken G, Grigoroiu-Serbanescu M, Diaconu CC, Czerski PM, Hauser J, Babadjanova G, Abramova LI, Mühleisen TW, Nöthen MM, Rietschel M, McGuffin P, Clair DS, Gustafsson O, Melle I, Pietiläinen OP, Ruggeri M, Tosato S, Werge T, Ophoff RA; GROUP Consortium, Rujescu D, Børglum AD, Mors O, Mortensen PB, Demontis D, Hollegaard MV, van Winkel R, Kenis G, De Hert M, Réthelyi JM, Bitter I, Rubino IA, Golimbet V, Kiemeney LA, van den Berg LH, Franke B, Jönsson EG, Farmer A, Stefansson H, Stefansson K, Collier DA.  Replication Study and Meta-Analysis in European Samples Supports Association of the 3p21.1 Locus with Bipolar Disorder.  Biol Psychiatry. 2012 Oct 15;72(8):645-50. doi: 10.1016/j.biopsych.2012.02.040..

1731 Velanac V, Unterbarnscheidt T, Hinrichs W, Gummert MN, Fischer TM, Rossner MJ, Trimarco A, Brivio V, Taveggia C, Willem M, Haass C, Möbius W, Nave KA, Schwab MH. Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination. Glia. 2012 Feb;60(2):203-17. doi: 10.1002/glia.21255. Epub 2011 Nov 2.

1730 Visser MJ, Landeck L, Campbell LE, McLean WH, Weidinger S, Calkoen F, John SM, Kezic S.  Impact of atopic dermatitis and loss-of-function mutations in the filaggrin gene on the development of occupational irritant contact dermatitis.  Br J Dermatol 2013; 168:326-332.

1729 Voelkel T, Andresen C, Unger A, Just S, Rottbauer W, Linke WA.  Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.  Biochim Biophys Acta. 2012 Oct 6. S0167-4889(12)00281-9.

1728 Vogel B, Keller A, Frese K, Kloos W, Kayvanpour E, Sedaghat-Hamedani F, Hassel S, Marquart S, Beier M, Giannitis E, Hardt S, Katus HA, Meder B.  Refining Diagnostic MicroRNA Signatures by Whole-miRNome Kinetic Analysis in Acute Myocardial Infarction.  Clin Chem. 2012 Dec 19. [Epub ahead of print].

1727 Vogel H, Scherneck S, Kanzleiter T, Benz V, Kluge R, Stadion M, Kryvych S, Blüher M, Klöting N, Joost HG, Schürmann A.  Loss of function of Ifi202b by a microdeletion on chromosome 1 of C57BL/6J mice suppresses 11?-hydroxysteroid dehydrogenase type 1 expression and  development of obesity.  Hum Mol Genet. 21, 3845-3857 (2012).

1726 Voight BF, Peloso GM, Orho-Melander M, Frikke-Schmidt R, Barbalic M, Jensen MK, Hindy G, Hólm H, Ding EL, Johnson T, Schunkert H, Samani NJ, Clarke R, Hopewell JC, Thompson JF, Li M, Thorleifsson G, Newton-Cheh C, Musunuru K, Pirruccello JP, Saleheen D, Chen L, Stewart A, Schillert A, Thorsteinsdottir U, Thorgeirsson G, Anand S, Engert JC, Morgan T, Spertus J, Stoll M, Berger K, Martinelli N, Girelli D, McKeown PP, Patterson CC, Epstein SE, Devaney J, Burnett MS, Mooser V, Ripatti S, Surakka I, Nieminen MS, Sinisalo J, Lokki ML, Perola M, Havulinna A, de Faire U, Gigante B, Ingelsson E, Zeller T, Wild P, de Bakker PI, Klungel OH, Maitland-van der Zee AH, Peters BJ, de Boer A, Grobbee DE, Kamphuisen PW, Deneer VH, Elbers CC, Onland-Moret NC, Hofker MH, Wijmenga C, Verschuren WM, Boer JM, van der Schouw YT, Rasheed A, Frossard P, Demissie S, Willer C, Do R, Ordovas JM, Abecasis GR, Boehnke M, Mohlke KL, Daly MJ, Guiducci C, Burtt NP, Surti A, Gonzalez E, Purcell S, Gabriel S, Marrugat J, Peden J, Erdmann J, Diemert P, Willenborg C, König IR, Fischer M, Hengstenberg C, Ziegler A, Buysschaert I, Lambrechts D, Van de Werf F, Fox KA, El Mokhtari NE, Rubin D, Schrezenmeir J, Schreiber S, Schäfer A, Danesh J, Blankenberg S, Roberts R, McPherson R, Watkins H, Hall AS, Overvad K, Rimm E, Boerwinkle E, Tybjaerg-Hansen A, Cupples LA, Reilly MP, Melander O, Mannucci PM, Ardissino D, Siscovick D, Elosua R, Stefansson K, O'Donnell CJ, Salomaa V, Rader DJ, Peltonen L, Schwartz SM, Altshuler D, Kathiresan S. Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet. 2012 Aug 11;380(9841):572-80.

1725 Volckmar AL, Bolze F, Jarick I, Knoll N, Scherag A, Reinehr T, Illig T, Grallert H, Wichmann HE, Wiegand S, Biebermann H, Krude H, Fischer-Posovszky P, Rief W, Wabitsch M, Klingenspor M, Hebebrand J, Hinney A.   Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants. BMC Med Genomics 2012; 5:65. doi: 10.1186/1755-8794-5-65.10.1186/1755-8794-5-65.

1724 Vollstädt-Klein, Sabine, Sabine Loeber, Anne Richter, Martina Kirsch, Patrick Bach, Christoph von der Goltz, Derik Hermann, Karl Mann and Falk Kiefer.  Validating incentive salience with fMRI:  association between mesolimbic cue-reactivity and attentional bias in alcohol-dependent patients. Addiction Biology 17(4):807-816.

1723 von dem Knesebeck A, Felsberg J, Waha A, Hartmann W, Scheffler B, Glas M, Hammes J, Mikeska T, Yan P S, Endl E, Simon M, Reifenberger G, Pietsch T and Waha A.  RANK (TNFRSF11A) is epigenetically inactivated and induces apoptosis in gliomas.  Neoplasia 2012 June;14(6): 526?534.

1722 von Kampen O, Buch S, Nothnagel M, Azocar L, Molina H, Brosch M, Erhart W, von Schönfels W, Egberts J, Seeger M, Arlt A, Balschun T, Franke A, Lerch MM, Mayerle J, Kratzer W, Boehm BO, Huse K, Schniewind B, Tiemann K, Jiang ZY, Han TQ, Mittal B, Srivastava A, Fenger M, Jørgensen T, Schirin-Sokhan R, Tönjes A, Wittenburg H, Stumvoll M, Kalthoff H, Lammert F, Tepel J, Puschel K, Becker T, Schreiber S, Platzer M, Völzke H, Krawczak M, Miquel JF, Schafmayer C, Hampe J.  Genetic and functional identification of the likely causative variant for cholesterol gallstone disease at the ABCG5/8 lithogenic locus.  Hepatology. 2012 Aug 16.

1721 von Schnurbein, J., A. Moss, S.A. Nagel, H. Muehleder, K.M. Debatin, I.S. Farooqi, and M. Wabitsch.   Leptin Substitution Results in the Induction of Menstrual Cycles in an Adolescent with Leptin Deficiency and Hypogonadotropic Hypogonadism. Horm Res Paediatr (2012). 

1720 Wahl S, Yu Z, Kleber M, Singmann P, Holzapfel C, He Y, Mittelstrass K, Polonikov A, Prehn C, Römisch-Margl W, Adamski J, Suhre K, Grallert H, Illig T, Wang-Sattler R, Reinehr T.  Childhood obesity is associated with changes in the serum metabolite profile.  Obes Facts. 2012;5(5):660-70. doi: 10.1159/000343204. Epub 2012 Oct 4.

1719 Walde S, Thakar K, Hutten S, Spillner C, Nath A, Rothbauer U, Wiemann S, Kehlenbach RH (2012)  The Nucleoporin Nup358/RanBP2 Promotes Nuclear Import in a Cargo- and Transport Receptor-Specific Manner.  Traffic 13: 218-233.

1718 Waltereit R, Leimer U, von Bohlen und Halbach O, Panke J, Hölter SM, Garrett L, Wittig K, Schneider M, Schmitt C, Calzada-Wack J, Neff F, Becker L, Prehn C, Kutscherjawy S, Endris V, Bacon C, Fuchs H, Gailus-Durner V, Berger S, Schönig K, Adamski J, Klopstock T, Esposito I, Wurst W, Hrabé de Angelis M, Rappold G, Wieland T, Bartsch D:  Srgap3-/- mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes.  FASEB J. 2012 Nov;26(11):4418-28. doi: 10.1096/fj.11-202317.

1717 Wang XD, Labermaier C, Holsboer F, Wurst W, Deussing JM, Müller MB, Schmidt MV.  Early-life stress-induced anxiety-related behavior in adult mice partially requires forebrain corticotropin-releasing hormone receptor 1.  Eur J Neurosci. 2012 Aug;36(3):2360-7. Epub 2012 Jun 4..

1716 Wang-Sattler R, Yu Z, Herder C, Messias AC, Floegel A, He Y, Heim K, Campillos M, Holzapfel C, Thorand B, Grallert H, Xu T, Bader E, Huth C, Mittelstrass K, Döring A, Meisinger C, Gieger C, Prehn C, Roemisch-Margl W, Carstensen M, Xie L, Yamanaka-Okumura H, Xing G, Ceglarek U, Thiery J, Giani G, Lickert H, Lin X, Li Y, Boeing H, Joost HG, de Angelis MH, Rathmann W, Suhre K, Prokisch H, Peters A, Meitinger T, Roden M, Wichmann HE, Pischon T, Adamski J, Illig T.  Novel biomarkers for pre-diabetes identified by metabolomics.  Mol Syst Biol. 2012;8:615. doi: 10.1038/msb.2012.43.

1715 Ward A, Balwierz A, Zhang JD, Küblbeck M, Pawitan Y, Hielscher T, Wiemann S, Sahin O.  Re-expression of microRNA-375 reverts both tamoxifen resistance and accompanied EMT-like properties in breast cancer.  Oncogene: 10.1038/onc.2012.128.

1714 Wash, R., Calabressi, S., Franz, S., Goulding, D., Tan, E.P., Nikolov, N., Skarnes, B., Bradley, A., Digard, P., Barclay, W., Haas, J., Efstathiou, S., Kellam, P.  Permissive and restricted virus infection of murine embryonic stem cells.  J Gen Virol. 93 :2118-30.

1713 Wefers B, Hitz C, Hölter SM, Trümbach D, Hansen J, Weber P, Pütz B, Deussing JM, de Angelis MH, Roenneberg T, Zheng F, Alzheimer C, Silva A, Wurst W, Kühn R.  MAPK signaling determines anxiety in the juvenile mouse brain but depression-like behavior in adults.  PLoS One. 2012;7(4):e35035. Epub 2012 Apr 18.

1712 Wegerer M, Adena S, Pfennig A, Czamara D, Sailer U, Bettecken T, Müller-Myhsok B, Modell S, Ising M.  Variants within the GABA transaminase (ABAT) gene region are associated with somatosensory evoked EEG potentials in families at high risk for affective disorders.  Psychol Med. 2012 Jan 9:1-11. [Epub ahead of print] PubMed PMID: 22225676.

1711 Weidner C, de Groot JC, Prasad A, Freiwald A, Quedenau C, Kliem M, Witzke A, Kodelja V, Han CT, Giegold S, Baumann M, Klebl B, Siems K, Müller-Kuhrt L, Schürmann A, Schüler R, Pfeiffer AF, Schroeder FC, Büssow K, Sauer S.  Amorfrutins are potent antidiabetic dietary natural products.  Proc Natl Acad Sci U S A. 109:7257-7262 (2012). 

1710 Westermann AJ, Gorski SA, Vogel J. Dual RNA-seq of pathogen and host Nat Reviews Microbiology 14;10(9):618-30

1709 Wierling C, Kühn A, Hache H, Daskalaki A, Maschke-Dutz E, Peycheva S, Li J, Herwig R, and Lehrach H.  Prediction in the face of uncertainty: a Monte Carlo-based approach for systems biology of cancer treatment.  Mutat Res. 2012 Aug 15;746(2):163-70. doi: 10.1016/j.mrgentox.2012.01.005. Epub 2012 Jan 23.

1708 Wilcke A, Ligges C, Burkhardt J, Alexander M, Wolf C, Quente E, Ahnert P, Hoffmann P, Becker A, Müller-Myhsok B, Cichon S, Boltze J, Kirsten H.  Imaging genetics of FOXP2 in dyslexia.  Eur J Hum Genet. 2012 Feb;20(2):224-9. doi: 10.1038/ejhg.2011.160. 

1707 Willour VL, Seifuddin F, Mahon PB, Jancic D, Pirooznia M, Steele J, Schweizer B, Goes FS, Mondimore FM, Mackinnon DF; The Bipolar Genome Study (BiGS) Consortium, Perlis RH, Lee PH, Huang J, Kelsoe JR, Shilling PD, Rietschel M, Nöthen MM, Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, Depaulo JR Jr, Schulze TG, McMahon FJ, Zandi PP, Potash JB.  A genome-wide association study of attempted suicide.  Mol Psychiatry. 2012 Apr;17(4):433-444. doi: 10.1038/mp.2011.4.

1706 Windhager L, Bonfert T, Burger K, Ruzsics Z, Krebs S, Kaufmann S, Malterer G, L'hernault A, Schilhabel M, Schreiber S, Rosenstiel P, Zimmer R, Eick D, Friedel CC, Dölken L. Ultra short and progressive 4sU-tagging reveals key characteristics of RNA processing at nucleotide resolution. Genome Research 2012 Apr 26.

1705 Winkelmann J, Lin L, Schormair B, Kornum BR, Faraco J, Plazzi G, Melberg A, Cornelio F, Urban AE, Pizza F, Poli F, Grubert F, Wieland T, Graf E, Hallmayer J, Strom TM, Mignot E.  Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy.  Hum Mol Genet. 2012 Feb 23. [Epub ahead of print] PubMed PMID: 22328086.

1704 Witt O, Milde T, Deubzer HE, Oehme I, Witt R, Kulozik A, Eisenmenger A, Abel U, Karapanagiotou-Schenkel I.  Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma or leukemia.  Klin Padiatr. 2012 Oct;224(6):398-403. doi: 10.1055/s-0032-1323692. Epub 2012 Aug 22.

1703 Wojciechowski P, Lipowska A, Rys P, Ewens KG, Franks S, Tan S, Lerchbaum E, Vcelak J, Attaoua R, Straczkowski M, Azziz R, Barber TM, Hinney A, Obermayer-Pietsch B, Lukasova P, Bendlova B, Grigorescu F, Kowalska I, Goodarzi MO; GIANT Consortium, Strauss JF 3rd, McCarthy MI, Malecki MT.  Impact of FTO genotypes on BMI and weight in polycystic ovary syndrome: a systematic review and meta-analysis.  Diabetologia. 2012 Oct;55(10):2636-45. doi: 10.1007/s00125-012-2638-6. Epub 2012 Jul 18. Review. Erratum in: Diabetologia. 2012 Oct;55(10):2858-9. PubMed PMID: 22801903; PubMed Central PMCID: PMC3433670.

1702 Wolff, D.; Endele, S.; Azzarello-Burri, S.; Hoyer, J.; Zweier, M.; Schanze, I.; Schmitt, B.;    Rauch, A.; Reis, A.; Zweier, C. In-Frame Deletion and Missense Mutation of the C-Terminal Helicase Domain of SMARCA2 in Three Patients with Nicolaides-Baraitser Syndrome Molecular Syndromology 2011;2:237-244 (DOI:10.1159/000337323).

1701 Wulfkuhle JD, Berg D, Wolff C, Langer R, Tran K, Illi J, Espina V, Pierobon M, Deng J, DeMichele A, Walch A, Bronger H, Becker I, Waldhör C, Höfler H, Esserman  L; I-SPY 1 TRIAL Investigators, Liotta LA, Becker KF, Petricoin EF 3rd. Molecular analysis of HER2 signaling in human breast cancer by functional protein pathway activation mapping. Clin Cancer Res. 2012 Dec 1;18(23):6426-35. doi: 10.1158/1078-0432.CCR-12-0452.

1700 Yang J, Loos RJ, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R, Waite L, Smith AV, Yerges-Armstrong LM, Monda KL, Hadley D, Mahajan A, Li G, Kapur K, Vitart V, Huffman JE, Wang SR, Palmer C, Esko T, Fischer K, Zhao JH, Demirkan A, Isaacs A, Feitosa MF, Luan J, Heard-Costa NL, White C, Jackson AU, Preuss M, Ziegler A, Eriksson J, Kutalik Z, Frau F, Nolte IM, Van Vliet-Ostaptchouk JV, Hottenga JJ, Jacobs KB, Verweij N, Goel A, Medina-Gomez C, Estrada K, Bragg-Gresham JL, Sanna S, Sidore C, Tyrer J, Teumer A, Prokopenko I, Mangino M, Lindgren CM, Assimes TL, Shuldiner AR, Hui J, Beilby JP, McArdle WL, Hall P, Haritunians T, Zgaga L, Kolcic I, Polasek O, Zemunik T, Oostra BA, Junttila MJ, Grönberg H, Schreiber S, Peters A, Hicks AA, Stephens J, Foad NS, Laitinen J, Pouta A, Kaakinen M, Willemsen G, Vink JM, Wild SH, Navis G, Asselbergs FW, Homuth G, John U, Iribarren C, Harris T, Launer L, Gudnason V, O'Connell JR, Boerwinkle E, Cadby G, Palmer LJ, James AL, Musk AW, Ingelsson E, Psaty BM, Beckmann JS, Waeber G, Vollenweider P, Hayward C, Wright AF, Rudan I, Groop LC, Metspalu A, Khaw KT, van Duijn CM, Borecki IB, Province MA, Wareham NJ, Tardif JC, Huikuri HV, Cupples LA, Atwood LD, Fox CS, Boehnke M, Collins FS, Mohlke KL, Erdmann J, Schunkert H, Hengstenberg C, Stark K, Lorentzon M, Ohlsson C, Cusi D, Staessen JA, Van der Klauw MM, Pramstaller PP, Kathiresan S, Jolley JD, Ripatti S, Jarvelin MR, de Geus EJ, Boomsma DI, Penninx B, Wilson JF, Campbell H, Chanock SJ, van der Harst P, Hamsten A, Watkins H, Hofman A, Witteman JC, Zillikens MC, Uitterlinden AG, Rivadeneira F, Zillikens MC, Kiemeney LA, Vermeulen SH, Abecasis GR, Schlessinger D, Schipf S, Stumvoll M, Tönjes A, Spector TD, North KE, Lettre G, McCarthy MI, Berndt SI, Heath AC, Madden PA, Nyholt DR, Montgomery GW, Martin NG, McKnight B, Strachan DP, Hill WG, Snieder H, Ridker PM, Thorsteinsdottir U, Stefansson K, Frayling TM, Hirschhorn JN, Goddard ME, Visscher PM. FTO genotype is associated with phenotypic variability of body mass index. Nature. 2012 Oct 11;490(7419):267-72. doi: 10.1038/nature11401. Epub 2012 Sep 16. PubMed PMID: 22982992; PubMed Central PMCID: PMC3564953.

1699 Yeritsyan N, Lehmann K, Puk O, Graw J, Löwel S.  Visual capabilities and cortical maps in BALB/c mice.  Eur J Neurosci. 2012 Sep; 36:2801-2811. doi10.1111/j.1460-9568.2012.08195.

1698 Yu W, Hegarty JP, Berg A, Kelly AA, Wang Y, Poritz LS, Franke A, Schreiber S, Koltun WA, Lin Z.  PTPN2 is associated with Crohn's disease and its expression is regulated by NKX2-3.  Dis Markers. 2012;32(2):83-91. doi: 10.3233/DMA-2011-086

1697 Zeidler, L., Zimmermann, M., Möricke, A., Meissner, B., Bartels, D., Tschan, C., Schrauder, A., Cario, G., Goudeva, L., Jäger, S., Ratei, R., Ludwig, W.D., Teigler-Schlegel, A., Skokowa, J., Koehler, R., Bartram, C.R., Riehm, H., Schrappe, M., Welte, K., Stanulla, M. Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome.  Haematologica. 2012, 97:402-9..

1696 Zhang J, Zhang L, Su X, Li M, Xie L, Malchers F, Fan S, Yin X, Xu Y, Liu K, Dong Z, Zhu G, Qian Z, Tang L, Zhan P, Ji Q, Kilgour E, Smith PD, Brooks AN, Thomas RK, Gavine PR.  Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models.  Clin Cancer Res. 2012 Dec 15;18(24):6658-67. doi: 10.1158/1078-0432.CCR-12-2694. Epub 2012 Oct 18.

1695 Zhao C, Shi L, Tong W, Shaughnessy JD Jr, Oberthuer A, Pusztai L, Deng Y, Symmans WF, Shi T. Maximum predictive power of the microarray-based models for clinical outcomes is limited by correlation between endpoint and gene expression profile. BMC Genomics. 2011 Dec 23;12 Suppl 5:S3.

1694 Zirbs M, Pürner C, Buters JT, Effner R, Weidinger S, Ring J, Eberlein B. GSTM1, GSTT1 and GSTP1 gene polymorphism in polymorphous light eruption. J Eur Acad Dermatol Venereol 2012; in press.

2011

1693 Abboud Leon C, Schumacher J, Kluck N, Herold C, Schulze TG, Propping P, Rietschel M, Cichon S, Nöthen MM, Abou Jamra R. Association study of the GRIA1 and CLINT1 (Epsin 4) genes in a German schizophrenia sample. Psychiatr Genet. 2010 Nov 24. [Epub ahead of print]

1692 Abe K, Fuchs H, Boersma A, Hans W, Yu P, Kalaydjiev S, Klaften M, Adler T, Calzada-Wack J, Mossbrugger I, Rathkolb B, Rozman J, Prehn C, Maraslioglu M, Kametani Y, Shimada S, Adamski J, Busch DH, Esposito I, Klingenspor M, Wolf E, Wurst W, Gailus-Durner V, Katan M, Marschall S, Soewarto D, Wagner S, de Angelis MH. A novel ENU-induced mutation in Phospholipase C gamma 2 causes inflammatory arthritis, metabolic defects, and in vitro male infertility in the mouse. Arthritis Rheum. 2011 Feb 4. doi: 10.1002/art.30280. [Epub ahead of print].

1691 Abou Jamra R, Philippe O, Raas-Rothschild A, Eck SH, Graf E, Buchert R, Borck G, Ekici A, Brockschmidt FF, Nöthen MM, Munnich A, Strom TM, Reis A, Colleaux L. Adaptor protein complex 4 deficiency causes severe autosomal-recessive intellectual disability, progressive spastic paraplegia, shy character, and short stature. Am J Hum Genet. 2011 Jun 10;88(6):788-95. Epub 2011 May 27. PMID: 21620353.

1690 Abou Jamra R, Wohlfart S, Zweier M, Uebe S, Priebe L, Ekici A, Giesebrecht S, Abboud A, Al Khateeb MA, Fakher M, Hamdan S, Ismael A, Muhammad S, Nöthen MM, Schumacher J, Reis A. Homozygosity mapping in 64 Syrian consanguineous families with non-specific intellectual disability reveals 11 novel loci and high heterogeneity. Eur J Hum Genet. 2011 Nov;19(11):1161-6. doi: 10.1038/ejhg.2011.98. Epub 2011 Jun 1.

1689 Abramov AY, Gegg M, Grunewald A, Wood NW, Klein C, Schapira AH. Bioenergetic consequences of PINK1 mutations in Parkinson disease. PLoS One 2011; 6:e25622.

1688 Ackermann S, Goeser F, Schulte JH, Schramm A, Ehemann V, Eggert A, Hero B, Berthold F, Fischer M. Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma. Clin Cancer Res, 2011, 17(4):731-741.

1687 Adamczyk KA, Klein-Scory S, Tehrani MM, Warnken U, Schmiegel W, Schnölzer M, Schwarte-Waldhoff I. Characterization of soluble and exosomal forms of the EGFR released from pancreatic cancer cells. Life Sci. 2011 Aug 29;89(9-10):304-12. Epub 2011 Jul 6

1686 Afanasyeva EA, Mestdagh P, Kumps C, Vandesompele J, Ehemann V, Theissen J, Fischer M, Zapatka M, Brors B, Savelyeva L, Sagulenko V, Speleman F, Schwab M, Westermann F. MicroRNA miR-885-5p targets CDK2 and MCM5, activates p53 and inhibits proliferation and survival. Cell Death Differ. 2011 Jan 14. [Epub ahead  of print]

1685 Agrawal-Singh S, Isken F, Agelopoulos K, Klein HU, Thoennissen NH, Koehler G, Hascher A, Bäumer N, Berdel WE, Thiede C, Ehninger G, Becker A, Schlenke P, Wang Y, McClelland M, Krug U, Koschmieder S, Büchner T, Yu DY, Singh SV, Hansen K, Serve H, Dugas M, Müller-Tidow C. Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene. Blood. 2012 Mar 8;119(10):2346-57. Epub 2011 Dec 29.

1684 Aigner B, Rathkolb B, Klempt M, Wagner S, Michel D, Klaften M, Laufs J, Schneider B, Sedlmeier R, Hrabé de Angelis M, Wolf E. Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters. Mamm Genome. 22(9-10):495-505. DOI:10.1007/s00335-011-9328-4

1683 Albayrak O, Albrecht B, Scherag S, Barth N, Hinney A, Hebebrand J. Successful methylphenidate treatment of early onset extreme obesity in a child with a melanocortin-4 receptor gene mutation and attention deficit/hyperactivity disorder. Eur J Pharmacol. 2011 Jan 3. [Epub ahead of print] PubMed PMID: 21211528.

1682 Albers C, Illert AL, Miething C, Leischner H, Thiede M, Peschel C, Duyster J. An RNAi-based system for loss-of-function analysis identifies Raf1 as a crucial mediator of BCR-ABL-driven leukemogenesis. Blood. 2011 Aug 25;118(8):2200-10.

1681 Albrecht M, Sharma CM, Dittrich MT, Müller T, Reinhardt R, Vogel J, Rudel T. The transcriptional landscape of Chlamydia pneumoniae. Genome Biol. 2011 Oct 11;12(10):R98.

1680 Allanore Y, Saad M, Dieudé P, Avouac J, Distler JH, Amouyel P, Matucci-Cerinic M, Riemekasten G, Airo P, Melchers I, Hachulla E, Cusi D, Wichmann HE, Wipff J, Lambert JC, Hunzelmann N, Tiev K, Caramaschi P, Diot E, Kowal-Bielecka O, Valentini G, Mouthon L, Czirják L, Damjanov N, Salvi E, Conti C, Müller M, Müller-Ladner U, Riccieri V, Ruiz B, Cracowski JL, Letenneur L, Dupuy AM, Meyer O, Kahan A, Munnich A, Boileau C, Martinez M. Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genetics 2011

1679 Allebrandt KV, Amin N, Müller-Myhsok B, Esko T, Teder-Laving M, Azevedo RV, Hayward C, van Mill J, Vogelzangs N, Green EW, Melville SA, Lichtner P, Wichmann HE, Oostra BA, Janssens AC, Campbell H, Wilson JF, Hicks AA, Pramstaller PP, Dogas Z, Rudan I, Merrow M, Penninx B, Kyriacou CP, Metspalu A, van Duijn CM, Meitinger T, Roenneberg T. A K(ATP) channel gene effect on sleep duration: from genome-wide association studies to function in Drosophila. Mol Psychiatry. 2011

1678 Amin N, Byrne E, Johnson J, Chenevix-Trench G, Walter S, Nolte IM; kConFabInvestigators, Vink JM, Rawal R, Mangino M, Teumer A, Keers JC, Verwoert G,Baumeister S, Biffar R, Petersmann A, Dahmen N, Doering A, Isaacs A, Broer L,Wray NR, Montgomery GW, Levy D, Psaty BM, Gudnason V, Chakravarti A, Sulem P, Gudbjartsson DF, Kiemeney LA, Thorsteinsdottir U, Stefansson K, van Rooij FJ, Aulchenko YS, Hottenga JJ, Rivadeneira FR, Hofman A, Uitterlinden AG, Hammond CJ, Shin SY, Ikram A, Witteman JC, Janssens AC, Snieder H, Tiemeier H, Wolfenbuttel BH, Oostra BA, Heath AC, Wichmann E, Spector TD, Grabe HJ, Boomsma DI, Martin NG, van Duijn CM. Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM. Mol Psychiatry. 2011 Aug 30.

1677 Andersen V, Ernst A, Sventoraityte J, Kupcinskas L, Jacobsen BA, Krarup HB, Vogel U, Jonaitis L, Denapiene G, Kiudelis G, Balschun T, Franke A. Assessment of heterogeneity between European Populations: a Baltic and Danish replication case-control study of SNPs from a recent European ulcerative colitis genome wide association study. BMC Med Genet 2011;12(1):139

1676 Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC,Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C, Ellinghaus D, Fehrmann RS, Floyd JA, Florin T, Franchimont D, Franke L, Georges M, Glas J, Glazer NL, Guthery SL, Haritunians T, Hayward NK, Hugot JP, Jobin G, Laukens D, Lawrance I, Lémann M, Levine A, Libioulle C, Louis E, McGovern DP, Milla M, Montgomery GW, Morley KI, Mowat C, Ng A, Newman W, Ophoff RA, Papi L, Palmieri O, Peyrin-Biroulet L, Panés J, Phillips A, Prescott NJ, Proctor DD, Roberts R, Russell R, Rutgeerts P,Sanderson J, Sans M, Schumm P, Seibold F, Sharma Y, Simms LA, Seielstad M, Steinhart AH, Targan SR, van den Berg LH, Vatn M, Verspaget H, Walters T, Wijmenga C, Wilson DC, Westra HJ, Xavier RJ, Zhao ZZ, Ponsioen CY, Andersen V, Torkvist L, Gazouli M, Anagnou NP, Karlsen TH, Kupcinskas L, Sventoraityte J, Mansfield JC, Kugathasan S, Silverberg MS, Halfvarson J, Rotter JI, Mathew CG, Griffiths AM, Gearry R, Ahmad T, Brant SR, Chamaillard M, Satsangi J, Cho JH, Schreiber S, Daly MJ, Barrett JC, Parkes M, Annese V, Hakonarson H, Radford-Smith G, Duerr RH, Vermeire S, Weersma RK, Rioux JD. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet. 2011 Mar;43(3):246-52. Epub 2011 Feb 6

1675 Andreas Keller, Christina Backes, Petra Leidinger, Nathalie Kefer, Valesca Boisguerin, Catalin Barbacioru, Britta Vogel, Mark Matzas, Hanno Huwer, Hugo A.Katus, Cord Stähler, Benjamin Meder*, Eckart Meese*. Next-generation sequencing identifies novel microRNAs in peripheral blood of lung cancer patients. Molecular Biosystems. 2011 (epub ahead). Dec;7(12):3187-99. Epub 2011 Oct 25.

1674 Angelova-Fischer I, Mannheimer AC, Hinder A, Ruether A, Franke A, Neubert RH, Fischer TW, Zillikens D. Distinct barrier integrity phenotypes in filaggrin-related atopic eczema following sequential tape stripping and lipid profiling. Exp Dermatol. 2011 Apr;20(4):351-6. doi: 10.1111/j.1600-0625.2011.01259.x.

1673 Appel IJ, Gronwald W, Spang R. Estimating classification probabilities in high-dimensional diagnostic studies. Bioinformatics. 2011 Sep 15;27(18):2563-70. Epub 2011 Jul 22.

1672 Apple FS, Blankenberg S, Morrow DA. Impact of biomarkers, proteomics, and genomics in cardiovascular disease. Clin Chem. 2012 Jan;58(1):1-2. Epub 2011 Nov 28

1671 Aranda B, Blankenburg H, Kerrien S, Brinkman FS, Ceol A, Chautard E, Dana JM, De Las Rivas J, Dumousseau M, Galeota E, Gaulton A, Goll J, Hancock RE, Isserlin R, Jimenez RC, Kerssemakers J, Khadake J, Lynn DJ, Michaut M, O'Kelly G, Ono K, Orchard S, Prieto C, Razick S, Rigina O, Salwinski L, Simonovic M, Velankar S, Winter A, Wu G, Bader GD, Cesareni G, Donaldson IM, Eisenberg D, Kleywegt GJ, Overington J, Ricard-Blum S, Tyers M, Albrecht M, Hermjakob H. PSICQUIC and PSISCORE: accessing and scoring molecular interactions. Nat Methods. 2011 Jun 29;8(7):528-9.

1670 Augustin I, Goidts V, Bongers A, Kerr G, Vollert G, Radlwimmer B, Hartmann C, Herold-Mende C, Reifenberger G, von Deimling A, Boutros M. The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis. EMBO Mol Med. 2012 Jan;4(1):38-51. doi: 10.1002/emmm.201100186. Epub 2011 Dec 7.

1669 Autran D et al. (2011). Maternal epigenetic pathways control parental contributions to Arabidopsis early embryogenesis. Cell 145(5):707-19

1668 Aydin D, Filippov MA, Tschäpe J-A, Gretz N, Prinz M, Eils R, Brors B, Müller UC. Comparative transcriptome profiling of Amyloid Precursor Protein family members in the adult cortex. BMC Genomics,  12:160.

1667 Aydin, D., Weyer, S. W. and Müller, UC. Functions of the APP gene family in the nervous system: insights from mouse models. Exp. Brain. Res. Sep 20. DOI: 10.1007/s00221-011-2861-2.

1666 Baessler A, Schlossbauer S, Stark K, Strack C, Riegger G, Schunkert H, Hengstenberg C, Fischer M. Adiponectin multimeric forms but not total adiponectin levels are associated with myocardial infarction in non-diabetic men. J Atheroscler Thromb. 2011; 18(7):616-27.

1665 Bai SW, Herrera-Abreu MT, Rohn J, Racine V, Tajadura V, Suryavanshi N, Bechtel S, Wiemann S, Baum B, Ridley AJ (2011). A novel strategy to identify and characterize a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration. BMC Biology 9: 54.

1664 Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nürnberg P, Striessnig J, Bolz HJ. Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness. Nat Neurosci. 2011 Jan;14(1):77-84. Epub 2010 Dec 5. PMID: 21131953 [PubMed - indexed for MEDLINE]

1663 Barbosa-Silva, A., J.F. Fontaine, E.R. Donnard, F. Stussi, J. Miguel-Ortega and M.A. Andrade-Navarro. 2011. PESCADOR, a web-based tool to extract and study biointeractions from PubMed queries. BMC Bioinformatics. 12:435.

1662 Barbus S, Tews B, Karra D, Hahn M, Radlwimmer B, Delhomme N, Hartmann C, Felsberg J, Krex D, Schackert G, Martinez R, Reifenberger G, Lichter P. Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors. J Natl Cancer Inst. 2011 Apr 6;103(7):598-606. Epub 2011 Feb 23.PMID: 21346226 [PubMed - indexed for MEDLINE]

1661 Barkhausen T, Tschernig T, Rosenstiel P, van Griensven M, Vonberg RP, DorschM, Mueller-Heine A, Chalaris A, Scheller J, Rose-John S, Seegert D, Krettek C,Waetzig GH. Selective blockade of interleukin-6 trans-signaling improves survivalin a murine polymicrobial sepsis model*. Crit Care Med. 2011 Mar 14. [Epub ahead of print] PubMed PMID: 21336117.

1660 Barth S., Meister G. & Grässer F.A. (2011). EBV-encoded miRNAs. Biochim. Biophys. Acta, 1808(11-12):631-640.

1659 Baudrexel S, Witte T, Seifried C, von Wegner F, Beissner F, Klein JC, Steinmetz H, Deichmann R, Roeper J, Hilker R. Resting state fMRI reveals increased subthalamic nucleus-motor cortex connectivity in Parkinson's disease. Neuroimage. 2011 Apr 15;55(4):1728-38

1658 Bauer T, Eils R, König R. RIP: the regulatory interaction predictor--a machine learning-based approach for predicting target genes of transcription factors, Bioinformatics, 27, 2239-47.

1657 Becker KF, Taylor CR. 'Liquid morphology': Immunochemical analysis of proteins extracted from formalin-fixed paraffin-embedded tissues: Combining proteomics with immunohistochemistry. Appl Immunohistochem Mol Morphol. 2011 Jan;19(1):1-9.

1656 Becker T, Herold C, Meesters C, Mattheisen M, Baur MP. Significance levels in genome-wide interaction analysis (GWIA). Ann Hum Genet. 2011 Jan;75(1):29-35. doi: 10.1111/j.1469-1809.2010.00610.x

1655 Becla, L., Lunshof, J.E., Gurwitz, D., Schulte In den Bäumen, T., Westerhoff, H.V., Lange, B.M.H., Brand, A. Health technology assessment in the era of personalized health care. Int J Technol Assess Health Care, 30:1-9

1654 Belmonte Mahon P, Pirooznia M, Goes FS, Seifuddin F, Steele J, Lee PH, Huang J, Hamshere ML; The Bipolar Genome Study (BiGS) Consortium, The Wellcome Trust Case Control Consortium Bipolar Disorder Group, Depaulo JR Jr, Kelsoe JR, Rietschel M, Nöthen M, Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, Schulze TG, McMahon FJ, Potash JB, Zandi PP. Genome-wide association analysis of age at onset and psychotic symptoms in bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2011 Apr;156(3):370-378. doi: 10.1002/ajmg.b.31172. Epub 2011 Feb 8.

1653 Bender C, von der Heyde S, Henjes F, Wiemann S, Korf U, Beissbarth T (2011). Inferring signalling networks from longitudinal data using sampling based approaches in the R-package 'ddepn'. BMC Bioinformatics 12: 291.

1652 Berg D, Langer R, Tran K, Walch A, Schuster T, Bronger H, Becker KF. Protein Microarray-based Comparison of HER2, Estrogen Receptor, and Progesterone Receptor Status in Core Biopsies and Surgical Specimens From FFPE Breast Cancer Tissues. Appl Immunohistochem Mol Morphol. 2011 Feb 2. [Epub ahead of print]

1651 Berg D, Langer R, Tran K, Walch A, Schuster T, Bronger H, Becker KF. Protein Microarray-based Comparison of HER2, Estrogen Receptor, and Progesterone Receptor Status in Core Biopsies and Surgical Specimens From FFPE Breast Cancer Tissues. Appl Immunohistochem Mol Morphol. 2011 Feb 2. [Epub ahead of print]

1650 Berg D, Wolff C, Langer R, Schuster T, Feith M, Slotta-Huspenina J, Malinowsky K, Becker KF. Discovery of new molecular subtypes in oesophageal adenocarcinoma. PLoS One. 2011;6(9):e23985. Epub 2011 Sep 23.

1649 Berg D, Wolff C, Malinowsky K, Tran K, Walch A, Bronger H, Schuster T, Höfler H, Becker KF. Profiling signalling pathways in formalin-fixed and paraffin-embedded breast cancer tissues reveals cross-talk between EGFR, HER2, HER3 and uPAR. J Cell Physiol. 2012 Jan;227(1):204-12. doi: 10.1002/jcp.22718.

1648 Berkel, S.; Tang, W. Mario Treviño, Miriam Vogt, Peter Gass, Stephen W. Scherer, Rolf Sprengel, Gerhard Schratt, Gudrun A. Rappold. Inherited and de novo SHANK2 variants associated to autism spectrum disorder impair neuronal morphogenesis and physiology. Human Molecular Genetics, 21:344-57,2012

1647 Bertram L. Alzheimer's genetics in the GWAS era: a continuing story of 'replications and refutations'. Curr Neurol Neurosci Rep 11(3):246-53.

1646 Beyer M, Thabet Y, Müller R, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld E, Böttcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, End E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL. Repression of SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol. 2011 Aug 14;12(9):898-907. doi: 10.1038/ni.2084.

1645 Bieschke J, Herbst M, Wiglenda T, Friedrich RP, Boeddrich A, Schiele F, Kleckers D, Lopez del Amo JM, Grüning BA, Wang Q, Schmidt MR, Lurz R, Anwyl R, Schnoegl S, Fändrich M, Frank RF, Reif B, Günther S, Walsh DM, Wanker EE. Small-molecule conversion of toxic oligomers to nontoxic ?-sheet-rich amyloid fibrils. Nat Chem Biol. 2011 Nov 20;8(1):93-101. doi: 10.1038/nchembio.719.

1644 Billmann-Born S, Till A, Arlt A, Lipinski S, Sina C, Latiano A, Annese V, Häsler R, Kerick M, Manke T, Seegert D, Hanidu A, Schäfer H, van Heel D, Li J, Schreiber S, Rosenstiel P. Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC. J Immunol. 2011 Apr 1;186(7):4027-38. Epub 2011 Feb 18.

1643 Bingmer M, Schiemann J, Roeper J, Schneider G. Measuring burstiness and regularity in oscillatory spike trains. J Neurosci Methods. 2011 Oct 15;201(2):426-37. Epub 2011 Aug 18

1642 Bis JC, Kavousi M, Franceschini N, Isaacs A, Abecasis GR, Schminke U, Post WS, Smith AV, Cupples LA, Markus HS, Schmidt R, Huffman JE, Lehtimäki T, Baumert J, Münzel T, Heckbert SR, Dehghan A, North K, Oostra B, Bevan S, Stoegerer EM, Hayward C, Raitakari O, Meisinger C, Schillert A, Sanna S, Völzke H, Cheng YC, Thorsson B, Fox CS, Rice K, Rivadeneira F, Nambi V, Halperin E, Petrovic KE, Peltonen L, Wichmann HE, Schnabel RB, Dörr M, Parsa A, Aspelund T, Demissie S, Kathiresan S, Reilly MP, Taylor K, Uitterlinden A, Couper DJ, Sitzer M, Kähönen M, Illig T, Wild PS, Orru M, Lüdemann J, Shuldiner AR, Eiriksdottir G, White CC, Rotter JI, Hofman A, Seissler J, Zeller T, Usala G, Ernst F, Launer LJ, D'Agostino RB Sr, O'Leary DH, Ballantyne C, Thiery J, Ziegler A, Lakatta EG, Chilukoti RK, Harris TB, Wolf PA, Psaty BM, Polak JF, Li X, Rathmann W, Uda M, Boerwinkle E, Klopp N, Schmidt H, Wilson JF, Viikari J, Koenig W, Blankenberg S, Newman AB, Witteman J, Heiss G, Duijn Cv, Scuteri A, Homuth G, Mitchell BD, Gudnason V, O'Donnell CJ; CARDIoGRAM Consortium.Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet. 2011 Sep 11; 43(10):940-7.

1641 Blumrich A, Zapatka M, Brueckner LM, Zheglo D, Schwab M, Savelyeva L. The FRA2C common fragile site maps to the borders of MYCN amplicons in neuroblastoma and is associated with gross chromosomal rearrangements in different cancers. Hum Mol Genet 2011 Apr 15;20(8):1488-501.

1640 Böger CA, Chen MH, Tin A, Olden M, Köttgen A, Deboer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, Peralta CA, Kutalik Z, Luan J, Zhao JH, Hwang SJ, Akylbekova E, Kramer H, van der Harst P, Smith AV, Lohman K, de Andrade M, Hayward C, Kollerits B, Tönjes A, Aspelund T, Ingelsson E, Eiriksdottir G, Launer LJ, Harris TB, Shuldiner AR, Mitchell BD, Arking DE, Franceschini N, Boerwinkle E, Egan J, Hernandez D, Reilly M, Townsend RR, Lumley T, Siscovick DS, Psaty BM, Kestenbaum B, Haritunians T, Bergmann S, Vollenweider P, Waeber G, Mooser V, Waterworth D, Johnson AD, Florez JC, Meigs JB, Lu X, Turner ST, Atkinson EJ, Leak TS, Aasarød K, Skorpen F, Syvänen AC, Illig T, Baumert J, Koenig W, Krämer BK, Devuyst O, Mychaleckyj JC, Minelli C, Bakker SJ, Kedenko L, Paulweber B, Coassin S, Endlich K, Kroemer HK, Biffar R, Stracke S, Völzke H, Stumvoll M, Mägi R, Campbell H, Vitart V, Hastie ND, Gudnason V, Kardia SL, Liu Y, Polasek O, Curhan G, Kronenberg F, Prokopenko I, Rudan I, Arnlöv J, Hallan S, Navis G; the CKDGen Consortium, Parsa A, Ferrucci L, Coresh J, Shlipak MG, Bull SB, Paterson AD; Paterson on behalf of DCCT/EDIC, Wichmann HE, Wareham NJ, Loos RJ, Rotter JI, Pramstaller PP, Cupples LA, Beckmann JS, Yang Q, Heid IM, Rettig R, Dreisbach AW, Bochud M, Fox CS, Kao WH. CUBN is a Gene Locus for Albuminuria. J Am Soc Nephrol 2011;22:555-570.

1639 Böger CA, Gorski M, Li M, Hoffmann MM, Huang C, Yang Q, Teumer A, Krane V, O'Seaghdha CM, Kutalik Z, Wichmann HE, Haak T, Boes E, Coassin S, Coresh J, Kollerits B, Haun M, Paulweber B, Köttgen A, Li G, Shlipak MG, Powe N, Hwang SJ, Dehghan A, Rivadeneira F, Uitterlinden A, Hofman A, Beckmann JS, Krämer BK, Witteman J, Bochud M, Siscovick D, Rettig R, Kronenberg F, Wanner C, Thadhani RI, Heid IM, Fox CS, Kao WH; CKDGen Consortium. Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD. PLoS Genetics 2011

1638 Bolze F, Rink N, Brumm H, Kühn R, Mocek S, Schwarz AE, Kless C, Biebermann H, Wurst W, Rozman J, Klingenspor M. Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo. Pharmacogenomics J. 2011 Oct 4. doi: 10.1038/tpj.2011.43. [Epub ahead of print]

1637 Bottolo L, Petretto E, Blankenberg S, Cambien F, Cook SA, Tiret L, Richardson S. Bayesian detection of expression quantitative trait loci hot spots. Genetics. 2011 Dec;189(4):1449-59. Epub 2011 Sep 16.

1636 Bouman L, Schlierf A, Lutz AK, Shan J, Deinlein A, Kast J, Galehdar Z, Palmisano V, Patenge N, Berg D, Gasser T, Augustin R, Trümbach D, Irrcher I, Park DS, Wurst W, Kilberg MS, Tatzelt J, Winklhofer KF. Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress. Cell Death Differ. 2011 May;18(5):769-82. Epub 2010 Nov 26.

1635 Brameier M, Herwig A, Reinhardt R, Walter L, Gruber J. Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs. Nucleic Acids Res. 2011 Jan; 39(2): 675-686

1634 Brase JC, Johannes M, Mannsperger H, Fälth M, Metzger J, Kacprzyk LA, Andrasiuk T, Gade S, Meister M, Sirma H, Sauter G, Simon R, Schlomm T, Beißbarth T, Korf U, Kuner R, Sültmann H, TMPRSS2-ERG -specific transcriptional modulation is associated with prostate cancer biomarkers and TGF-? signaling. BMC Cancer, 2011, 11(1):507

1633 Brase JC, Johannes M, Schlomm T, Fälth M, Haese A, Steuber T, Beissbarth T, Kuner R, Sültmann H. Circulating miRNAs are correlated with tumor progression in prostate cancer. Int J Cancer. 2011;128:608-16

1632 Braun U, Plichta MM, Esslinger C, Sauer C, Haddad L, Grimm O, Mier D, Mohnke S, Heinz A, Erk S, Walter H, Seiferth N, Kirsch P, Meyer-Lindenberg A. Test-retest reliability of resting-state connectivity network characteristics using fMRI and graph theoretical measures. Neuroimage. 2012 Jan 16;59(2):1404-12. Epub 2011 Aug 23

1631 Brehmer S, Pusch S, Schmieder K, von Deimling A, Hartmann C.; Mutational analysis of D2HGDH and L2HGDH in brain tumors without IDH1 or IDH2 mutations. Neuropathol Appl Neurobiol. 2011 Apr;37(3):330-2.

1630 Brumm H, Mühlhaus J, Bolze F, Scherag S, Hinney A, Hebebrand J, Wiegand S, Klingenspor M, Grüters A, Krude H, Biebermann H. Rescue of Melanocortin 4 Receptor (MC4R) Nonsense Mutations by Aminoglycoside-Mediated Read-Through. Obesity (Silver Spring). 2011 Jul 7. doi: 10.1038/oby.2011.202. [Epub ahead of print] PubMed PMID: 21738238.

1629 Bucher K, Dietz K, Lackner P, Pasche B, Fendel R, Mordmüller B, Ben-Smith A, Hoffmann WH. Schistosoma co-infection protects against brain pathology but does not prevent severe disease and death in a murine model of cerebral malaria. Int J Parasitol. 2011 Jan;41(1):21-31. PMID: 20708623

1628 Buchholz M, und Gress TM. Molekulare Pathogenese zystischer Neoplasien im Pankreas. Viszeralmedizin 27:189?193.

1627 Burbulla LF, Krüger R. (2011). Converging pathways of genes and environment in the pathogenesis of Parkinson?s disease. J Neurol Sci 306: 1-8

1626 Bussmann C, Weidinger S, Novak N. Genetics of atopic dermatitis. J Dtsch Dermatol Ges 2011; 9:670-6

1625 Butler EK, Voigt A, Lutz AK, Toegel JP, Gerhardt E, Karsten P, Falkenburger B, Reinartz A, Winklhofer KF, Schulz JB. The Mitochondrial Chaperone Protein TRAP1 Mitigates ?-Synuclein Toxicity. PLoS Genet 8(2): e1002488. doi:10.1371

1624 Buyandelger B, Ng KE, Miocic S, Piotrowska I, Gunkel S, Ku CH, Knöll R. MLP (muscle LIM protein) as a stress sensor in the heart. Pflugers Arch. 2011; 462:135-42.

1623 C Reactive Protein Coronary Heart Disease Genetics Collaboration (CCGC), Wensley F, Gao P, Burgess S, Kaptoge S, Di Angelantonio E, Shah T, Engert JC, Clarke R, Davey-Smith G, Nordestgaard BG, Saleheen D, Samani NJ, Sandhu M, Anand S, Pepys MB, Smeeth L, Whittaker J, Casas JP, Thompson SG, Hingorani AD, Danesh J. Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data. BMJ. 2011;342:d548.

1622 Campos B., Centner F.S., Lorenzo Bermejo J., Ali R., Dorsch K., Wan F., Felsberg J., Ahmadi R., Grabe N., Reifenberger G., Unterberg A., Burhenne J., Herold-Mende C. Aberrant Expression of Retinoic Acid Signaling Molecules Influences Patient Survival in Astrocytic Gliomas. Am J Pathol.

2011 May;178(5):1953-64.
1621 Campos B., Lorenzo Bermejo J., Han L., Felsberg J., Ahmadi R, Grabe N., Reifenberger G., Unterberg A., Herold-Mende C. Expression of Nuclear Receptor Corepressors and Class I Histone Deacetylases in Astrocytic Gliomas. Cancer Sci. 2011 Feb;102(2):387-92. doi: 10.1111/j.1349-7006.2010.01792.x. Epub 2010 Dec 10.

1620 Campos B., Zeng L., DaoTrong P.H., Eckstein V., Unterberg A., Mairbäurl H., Herold-Mende C. Expression and Regulation of AC133 and CD133 in Glioblastoma. Glia. 2011 Dec;59(12):1974-86. doi: 10.1002/glia.21239. Epub 2011 Sep 7.

1619 Carlsson T, Schindler FR, Höllerhage M, Depboylu C, Arias-Carrión O, Schnurrbusch S, Rösler TW, Wozny W, Schwall GP, Groebe K, Oertel WH, Brundin P, Schrattenholz A, Höglinger GU. Systemic administration of neuregulin-1?1 protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neurochem. 2011 Jun;117(6):1066-74. doi: 10.1111/j.1471-4159.2011.07284.x

1618 Castagné R, Rotival M, Zeller T, Wild PS, Truong V, Trégouët DA, Munzel T, Ziegler A, Cambien F, Blankenberg S, Tiret L. The choice of the filtering method in microarrays affects the inference regarding dosage compensation of the active X-chromosome. PLoS One. 2011;6(9):e23956

1617 Castagné R, Zeller T, Rotival M, Szymczak S, Truong V, Schillert A, Trégouët DA, Münzel T, Ziegler A, Cambien F, Blankenberg S, Tiret L. Influence of sex and genetic variability on expression of X-linked genes in human monocytes. Genomics. 2011 Nov;98(5):320-6.

1616 Castro, F.A., Försti, A., Buch, S., Kalthoff, H., Krauss, C., Bauer, M., Egberts, J., Schniewind, B., Broering, D.C., Schreiber, S., Schmitt, M., Hampe, J., Hemminki, K. und Schafmayer, C. TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer. Eur J Cancer 47, 1203-1210.

1615 Chambers JC, Zhang W, Sehmi J, Li X, Wass MN, Van der Harst P, Holm H, Sanna S, Kavousi M, Baumeister SE, Coin LJ, Deng G, Gieger C, Heard-Costa NL, Hottenga JJ, Kühnel B, Kumar V, Lagou V, Liang L, Luan J, Vidal PM, Mateo Leach I, O'Reilly PF, Peden JF, Rahmioglu N, Soininen P, Speliotes EK, Yuan X, Thorleifsson G, Alizadeh BZ, Atwood LD, Borecki IB, Brown MJ, Charoen P, Cucca F, Das D, de Geus EJ, Dixon AL, Döring A, Ehret G, Eyjolfsson GI, Farrall M, Forouhi NG, Friedrich N, Goessling W, Gudbjartsson DF, Harris TB, Hartikainen AL, Heath S, Hirschfield GM, Hofman A, Homuth G, Hyppönen E, Janssen HL, Johnson T, Kangas AJ, Kema IP, Kühn JP, Lai S, Lathrop M, Lerch MM, Li Y, Liang TJ, Lin JP, Loos RJ, Martin NG, Moffatt MF, Montgomery GW, Munroe PB, Musunuru K, Nakamura Y, O'Donnell CJ, Olafsson I, Penninx BW, Pouta A, Prins BP, Prokopenko I, Puls R, Ruokonen A, Savolainen MJ, Schlessinger D, Schouten JN, Seedorf U, Sen-Chowdhry S, Siminovitch KA, Smit JH, Spector TD, Tan W, Teslovich TM, Tukiainen T, Uitterlinden AG, Van der Klauw MM, Vasan RS, Wallace C, Wallaschofski H, Wichmann HE, Willemsen G, Würtz P, Xu C, Yerges-Armstrong LM; Alcohol Genome-wide Association (AlcGen) Consortium; Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study; Genetic Investigation of Anthropometric Traits (GIANT) Consortium; Global Lipids Genetics Consortium; Genetics of Liver Disease (GOLD) Consortium; International Consortium for Blood Pressure (ICBP-GWAS); Meta-analyses of Glucose and Insulin-Related Traits Consortium (MAGIC), Abecasis GR, Ahmadi KR, Boomsma DI, Caulfield M, Cookson WO, van Duijn CM, Froguel P, Matsuda K, McCarthy MI, Meisinger C, Mooser V, Pietiläinen KH, Schumann G, Snieder H, Sternberg MJ, Stolk RP, Thomas HC, Thorsteinsdottir U, Uda M, Waeber G, Wareham NJ, Waterworth DM, Watkins H, Whitfield JB, Witteman JC, Wolffenbuttel BH, Fox CS, Ala-Korpela M, Stefansson K, Vollenweider P, Völzke H, Schadt EE, Scott J, Järvelin MR, Elliott P, Kooner JS. Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet

1614 Charlet K, Naundorf K, Dornhof L, Schlagenhauf F, Beck A, Gallinat J, Heinz A. Altered implicit neuronal processing of negative emotional facial expressions in alcohol-dependent patients. European Neuropsychopharmacology. The Journal of the European College of Neuropsychopharmacology: Volume 21 (2011), Supplement 3, Page S317

1613 Chasman DI, Schürks M, Anttila V, de Vries B, Schminke U, Launer LJ, Terwindt GM, van den Maagdenberg A, Fendrich K, Völzke H, Ernst F, Griffiths LR, Buring JE, Kallela M, Freilinger T, Kubisch C, Ridker PM, Palotie A, Ferrari MD, Hoffmann W, Zee RYL, Kurth T. Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nature Genet 2011;43:695-698

1612 Chen DT, Jiang X, Akula N, Shugart YY, Wendland JR, Steele CJ, Kassem L, Park JH, Chatterjee N, Jamain S, Cheng A, Leboyer M, Muglia P, Schulze TG, Cichon S, Nöthen MM, Rietschel M; BiGS, McMahon FJ. Genome-wide association study meta-analysis of European and Asian-ancestry samples identifies three novel loci associated with bipolar disorder. Mol Psychiatry. 2011 Dec 20. doi: 10.1038/mp.2011.157. [Epub ahead of print]

1611 Chen G, Carlson VC, Wang J, Beck A, Heinz A, Ron D, Lovinger DM, Buck KJ: Striatal Involvement in Human Alcoholism and Alcohol Consumption, and Withdrawal in Animal Models. Alcohol Clin Exp Res. 35(10):1739-48 (2011)

1610 Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O?Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V, Straub RE, Weinberger DR, O?Neill FA, Walsh D, Bronstein M, Darvasi A, Lencz T, Malhotra AK, Rujescu D, Giegling I, Werge T, Hansen T, Ingason A, Noethen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Cantor RM, Ophoff R, Corvin A, Morris DW, Gill M, Pato CN, Pato MT, Macedo A, Gurling HM, McQuillin A, Pimm J, Hultman C, Lichtenstein P, Sklar P, Purcell SM, Scolnick E, St Clair D, Blackwood DH, Kendler KS. GWA study data mining and independent replication identify cardiomyopathy-associated 5 (DMYA5) as a risk gene for schizophrenia. Mol Psychiatry. 2011 Nov;16(11):1117-29. doi: 10.1038/mp.2010.96

1609 Chertoff M, Di Paolo N, Schoeneberg A, Depino A, Ferrari C, Wurst W, Pfizenmaier K, Eisel U, Pitossi F. Neuroprotective and neurodegenerative effects of the chronic expression of tumor necrosis factor ? in the nigrostriatal dopaminergic circuit of adult mice. Exp Neurol. 2011 Feb;227(2):237-51. Epub 2010 Nov 17.

1608 Chiocchetti A, Pakalapati G, Duketis E, Wiemann S, Poustka A, Poustka F, Klauck SM. Mutation and expression analyses of the ribosomal protein gene RPL10 in an extended German sample of patients with autism spectrum disorder. Am J Med Genet A 155: 1472-1475.

1607 Chmielecki J, Foo J, Oxnard GR, Hutchinson K, Ohashi K, Somwar R, Wang L, Amato KR, Arcila M, Sos ML, Socci ND, Viale A, de Stanchina E, Ginsberg MS, Thomas RK, Kris MG, Inoue A, Ladanyi M, Miller VA, Michor F, Pao W. Optimization of dosing for EGFR-mutant non-small cell lung cancer with evolutionary cancer modeling. Sci Transl Med. 2011 Jul 6;3(90):90ra59.

1606 Cho MK, Kim HY, Fernandez CO, Becker S, Zweckstetter M. Conserved core of amyloid fibrils of wild type and A30P mutant ?-synuclein. Protein Sci. 2011 Feb;20(2):387-95.

1605 Cichon S, Mühleisen TW, Degenhardt FA, Mattheisen M, Miró X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, Schmäl C, Tessmann P, Moebus S, Wichmann HE, Schreiber S, Müller-Myhsok B, Lucae S, Jamain S, Leboyer M, Bellivier F, Etain B, Henry C, Kahn JP, Heath S; Bipolar Disorder Genome Study (BiGS) Consortium, Hamshere M, O'Donovan MC, Owen MJ, Craddock N, Schwarz M, Vedder H, Kammerer-Ciernioch J, Reif A, Sasse J, Bauer M, Hautzinger M, Wright A, Mitchell PB, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, Gustafsson O, Andreassen O, Djurovic S, Sigurdsson E, Steinberg S, Stefansson H, Stefansson K, Kapur-Pojskic L, Oruc L, Rivas F, Mayoral F, Chuchalin A, Babadjanova G, Tiganov AS, Pantelejeva G, Abramova LI, Grigoroiu-Serbanescu M, Diaconu CC, Czerski PM, Hauser J, Zimmer A, Lathrop M, Schulze TG, Wienker TF, Schumacher J, Maier W, Propping P, Rietschel* M, Nöthen* MM: Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet. 88:372-81, 2011. DOI: 10.1016/j.ajhg.2011.01.017

1604 Cin H, Meyer C, Herr R, Janzarik WG, Lambert S, Jones DT, Jacob K, Benner A, Witt H, Remke M, Bender S, Falkenstein F, Van Anh TN, Olbrich H, von Deimling A, Pekrun A, Kulozik AE, Gnekow A, Scheurlen W, Witt O, Omran H, Jabado N, Collins VP, Brummer T, Marschalek R, Lichter P, Korshunov A, Pfister SM. Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma. Acta Neuropathol. 2011 Jun;121(6):763-74. Epub 2011 Mar 20. PMID: 21424530 [PubMed - indexed for MEDLINE]

1603 Clarke TK, Laucht M, Ridinger M, Wodarz N, Rietschel M, Maier W, Lathrop M, Lourdusamy A, Zimmermann US, Desrivieres S, Schumann G. KCNJ6 is associated with adult alcohol dependence and involved in gene × early life stress interactions in adolescent alcohol drinking. Neuropsychopharmacology. 2011 May;36(6):1142-8.

1602 Coco S, Valdora F, Bonassi S, Scaruffi P, Stigliani S, Oberthuer A, Berthold F, Andolfo I, Servidei T, Riccardi R, Basso E, Iolascon A, Tonini GP. Chromosome 9q and 16q Loss Identified by Genome-Wide Pooled-Analysis Are Associated with Tumor Aggressiveness in Patients with Classic Medulloblastoma. OMICS. 2011 Feb 24

1601 Conde L, Bevan S, Sitzer M, Klopp N, Illig T, Thiery J, Seissler J, Baumert J, Raitakari O, Kähönen M, Lyytikäinen LP, Laaksonen R, Viikari J, Lehtimäki T, Koenig W, Halperin E, Markus HS. Novel associations for coronary artery disease derived from genome wide association studies are not associated with increased carotid intima-media thickness, suggesting they do not act via early atherosclerosis or vessel remodeling. Atherosclerosis 2011;219(2):684-9.

1600 Conrad C, Wünsche A, Tan TH, Bulkescher J, Sieckmann F, Verissimo F, Edelstein A, Walter T, Liebel U, Pepperkok R, Ellenberg J. Micropilot: automation of fluorescence microscopy-based imaging for systems biology. Nat Methods. 2011 Mar;8(3):246-9. Epub 2011 Jan 23.

1599 Däbritz J, Friedrichs F, Weinhage T, Hampe J, Kucharzik T, Lügering A, Broeckel U, Schreiber S, Spieker T, Stoll M, Foell D. The functional -374T/A polymorphism of the receptor for advanced glycation end products may modulate Crohn's disease. Am J Physiol Gastrointest Liver Physiol. 2011 May;300(5):G823-32. Epub 2011 Feb 10

1598 Dasari M, Espargaro A, Sabate R, Lopez Del Amo JM, Fink U, Grelle G, Bieschke J, Ventura S, Reif B. Bacterial inclusion bodies of Alzheimer's disease beta-amyloid peptides can be employed to study native-like aggregation intermediate states. Chembiochem. 2011 Feb 11;12(3).

1597 Dedic N, Touma C, Romanowski CP, Schieven M, Kühne C, Ableitner M, Lu A, Holsboer F, Wurst W, Kimura M, Deussing JM. Assessing Behavioural Effects of Chronic HPA Axis Activation Using Conditional CRH-Overexpressing Mice. Cell Mol Neurobiol. 2011 Dec 25. [Epub ahead of print]

1596 Dehghan A, Dupuis J, Barbalic M, Bis JC, Eiriksdottir G, Lu C, Pellikka N, Wallaschofski H, Kettunen J, Henneman P, Baumert J, Strachan DP, Fuchsberger C, Vitart V, Wilson JF, Paré G, Naitza S, Rudock ME, Surakka I, de Geus EJ, Alizadeh BZ, Guralnik J, Shuldiner A, Tanaka T, Zee RY, Schnabel RB, Nambi V, Kavousi M, Ripatti S, Nauck M, Smith NL, Smith AV, Sundvall J, Scheet P, Liu Y, Ruokonen A, Rose LM, Larson MG, Hoogeveen RC, Freimer NB, Teumer A, Tracy RP, Launer LJ, Buring JE, Yamamoto JF, Folsom AR, Sijbrands EJ, Pankow J, Elliott P, Keaney JF, Sun W, Sarin AP, Fontes JD, Badola S, Astor BC, Hofman A, Pouta A, Werdan K, Greiser KH, Kuss O, Meyer Zu Schwabedissen HE, Thiery J, Jamshidi Y, Nolte IM, Soranzo N, Spector TD, Völzke H, Parker AN, Aspelund T, Bates D, Young L, Tsui K, Siscovick DS, Guo X, Rotter JI, Uda M, Schlessinger D, Rudan I, Hicks AA, Penninx BW, Thorand B, Gieger C, Coresh J, Willemsen G, Harris TB, Uitterlinden AG, Järvelin MR, Rice K, Radke D, Salomaa V, Willems van Dijk K, Boerwinkle E, Vasan RS, Ferrucci L, Gibson QD, Bandinelli S, Snieder H, Boomsma DI, Xiao X, Campbell H, Hayward C, Pramstaller PP, van Duijn CM, Peltonen L, Psaty BM, Gudnason V, Ridker PM, Homuth G, Koenig W, Ballantyne CM, Witteman JC, Benjamin EJ, Perola M, Chasman DI. Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple Loci for C-reactive protein levels. Circulation 2011;123:731-8.

1595 Del Greco MF et al. (2011). Genome-wide association analysis and fine mapping of NT-proBNP level provide novel insight into the role of the MTHFR-CLCN6-NPPA-NPPB gene cluster. Hum Mol Genet 20(8):1660-1671.

1594 Demirkan A, Amin N, Isaacs A, Jarvelin MR, Whitfield JB, Wichmann HE, Kyvik KO, Rudan I, Gieger C, Hicks AA, Johansson Å, Hottenga JJ, Smith JJ, Wild SH, Pedersen NL, Willemsen G, Mangino M, Hayward C, Uitterlinden AG, Hofman A, Witteman J, Montgomery GW, Pietiläinen KH, Rantanen T, Kaprio J, Döring A, Pramstaller PP, Gyllensten U, de Geus EJ, Penninx BW, Wilson JF, Rivadeneria F, Magnusson PK, Boomsma DI, Spector T, Campbell H, Hoehne B, Martin NG, Oostra BA, McCarthy M, Peltonen-Palotie L, Aulchenko Y, Visscher PM, Ripatti S, Janssens AC, van Duijn CM; ENGAGE CONSORTIUM. Genetic architecture of circulating lipid levels. Eur. J. Hum. Genet. 2011

1593 Desrivières S, Pronko SP, Lourdusamy A, Ducci F, Hoffman PL, Wodarz N, Ridinger M, Rietschel M, Zelenika D, Lathrop M, Schumann G, Tabakoff B. Sex-specific role for adenylyl cyclase type 7 in alcohol dependence. Biol Psychiatry. 2011 Jun 1;69(11):1100-8.

1592 Devigny C, Perez-Balderas F, Hoogeland B, Cuboni S, Wachtel R, Mauch CP, Webb KJ, Deussing JM, Hausch F. Biomimetic screening of class-B G protein-coupled receptors. J Am Chem Soc. 2011 Jun 15;133(23):8927-33. Epub 2011 May 23.

1591 D'Haens GR, Panaccione R, Higgins PD, Vermeire S, Gassull M, Chowers Y, Hanauer SB, Herfarth H, Hommes DW, Kamm M, Löfberg R, Quary A, Sands B, Sood A, Watermeyer G, Lashner B, Lémann M, Plevy S, Reinisch W, Schreiber S, Siegel C, Targan S, Watanabe M, Feagan B, Sandborn WJ, Colombel JF, Travis S. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response? Am J Gastroenterol. 2011 Feb;106(2):199-212; quiz 213. Epub 2010 Nov

1590 Di Benedetto B, Kühn R, Nothdurfter C, Rein T, Wurst W, Rupprecht R. N-desalkylquetiapine activates ERK1/2 to induce GDNF release in C6 glioma cells: a putative cellular mechanism for quetiapine as antidepressant. Neuropharmacology. 2012 Jan;62(1):209-16. Epub 2011 Jul 13.

1589 Di Gion P, Kanefendt F, Lindauer A, Scheffler M, Doroshyenko O, Fuhr U, Wolf J, and Jaehde U. Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on pyrimidines, pyridines and pyrroles. Clin Pharmacokinet. 2011 vol. 50 (9) pp. 551-603.

1588 Dieudé P, Bouaziz M, Guedj M, Riemekasten G, Airò P, Müller M, Cusi D, Matucci-Cerinic M, Melchers I, Koenig W, Salvi E, Wichmann HE, Cuomo G, Hachulla E, Diot E, Hunzelmann N, Caramaschi P, Mouthon L, Riccieri V, Distler J, Tarner I, Avouac J, Meyer O, Kahan A, Chiocchia G, Boileau C, Allanore Y. Evidence of the contribution of the X chromosome to systemic sclerosis susceptibility: association with the functional IRAK1 196Phe/532Ser haplotype. Arthritis Rheum. 2011

1587 Dignass A, Preiss JC, Aust DE, Autschbach F, Ballauff A, Barretton G, Bokemeyer B, Fichtner-Feigl S, Hagel S, Herrlinger KR, Jantschek G, Kroesen A, Kruis W, Kucharzik T, Langhorst J, Reinshagen M, Rogler G, Schleiermacher D, Schmidt C, Schreiber S, Schulze H, Stange E, Zeitz M, Hoffmann JC, Stallmach A. [Updated German guideline on diagnosis and treatment of ulcerative colitis, 2011] Z Gastroenterol. 2011 Sep;49(9):1276-341. Epub 2011 Aug 24. German.

1586 Ding L, Poser I, Paszkowski-Rogacz M, Buchholz F. From RNAi Screens to Molecular Function in Embryonic Stem Cells. Stem Cell Rev. 2011 Apr 28.

1585 Dittmann LM, Danner A, Gronych J, Wolter M, Stühler K, Grzendowski M, Becker N, Bageritz J, Goidts V, Toedt G, Felsberg J, Sabel MC, Barbus S, Reifenberger G, Lichter P, Tews B. Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro. Oncogene. 2012 Jul 19;31(29):3409-18. doi: 10.1038/onc.2011.513. Epub 2011 Dec 12.

1584 Dolmans GH, Werker PM, Hennies HC, Furniss D, Festen EA, Franke L, Becker K, van der Vlies P, Wolffenbuttel BH, Tinschert S, Toliat MR, Nothnagel M, Franke A, Klopp N, Wichmann HE, Nürnberg P, Giele H, Ophoff RA, Wijmenga C; Dutch Dupuytren Study Group; German Dupuytren Study Group; LifeLines Cohort Study; BSSH-GODD Consortium (2011). Wnt signaling and Dupuytren's disease. N Engl J Med, 365(4):307-17.

1583 Domanskyi A, Geißler C, Vinnikov IA, Alter H, Schober A, Vogt MA, Gass P, Parlato R, Schütz G. P. Pten ablation in adult dopaminergic neurons is neuroprotective in  Parkinson´s disease models. FASEB J. 2011; 25:2898-2910. Epub May 18, 2011.

1582 Doncheva NT, Klein K, Domingues FS, Albrecht M. Analyzing and visualizing residue networks of protein structures. Trends Biochem Sci. 2011 Apr;36(4):179-82.

1581 Dong L, Bilbao A, Laucht M, Henriksson R, Yakovleva T, Ridinger M, Desrivieres S, Clarke TK, Lourdusamy A, Smolka MN, Cichon S, Blomeyer D, Treutlein J, Perreau-Lenz S, Witt S, Leonardi-Essmann F, Wodarz N, Zill P, Soyka M, Albrecht U, Rietschel M, Lathrop M, Bakalkin G, Spanagel R, Schumann G. Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking. American Journal of Psychiatry. 2011 Oct;168(10):1090-8. PubMed PMID: 21828288.

1580 Donnard, E., A. Barbosa-Silva, R.M. Guedes, G. Fernandes, H. Velloso, M.J. Kohn, M.A. Andrade-Navarro, J.M. Ortega. 2011. Preimplantation development regulatory pathway construction through a text-mining approach. BMC Genomics 2011, 12 Suppl 4:S3.

1579 Eckert C, Flohr T, Koehler R, Hagedorn N, Moericke A, Stanulla M, Kirschner-Schwabe R, Cario G, von Stackelberg A, Bartram C, Henze G, Schrappe M, Schrauder A. Very early/early relapses of acute lymphoblastic leukemia show unexpected changes of clonal markers and high heterogeneity in response to initial and relapse treatment. Leukemia. 2011 Aug; 25(8):1305-13. doi 10.1038/leu.2011.89

1578 Edmondson AC, Braund PS, Stylianou IM, Khera AV, Nelson CP, Wolfe ML, Derohannessian SL, Keating BJ, Qu L, He J, Tobin MD, Tomaszewski M, Baumert J, Klopp N, Doering A, Thorand B, Li M, Reilly MP, Koenig W, Samani NJ, Rader DJ. Dense Genotyping of Candidate F´Gene Loci Identifies Variants Associated with High-Density Lipoprotein Cholesterol. Circ Cardiovasc Genet 2011;4(2):145-155.

1577 Ehlermann P, Lehrke S, Papavassiliu T, Meder B, Borggrefe M, Katus HA, Schimpf R. Sudden cardiac death in a patient with lamin A/C mutation in the absence of dilated cardiomyopathy or conduction disease. Clin Res Cardiol. 2011 Feb 16. (epub ahead of print)

1576 Elbaz A, Ross OA, Ioannidis JP, Soto-Ortolaza AI, Moisan F, Aasly J, Annesi G, Bozi M, Brighina L, Chartier-Harlin MC, Destée A, Ferrarese C, Ferraris A, Gibson JM, Gispert S, Hadjigeorgiou GM, Jasinska-Myga B, Klein C, Krüger R, Lambert JC, Lohmann K, van de Loo S, Loriot MA, Lynch T, Mellick GD, Mutez E, Nilsson C, Opala G, Puschmann A, Quattrone A, Sharma M, Silburn PA, Stefanis L, Uitti RJ, Valente EM, Vilariño-Güell C, Wirdefeldt K, Wszolek ZK, Xiromerisiou G, Maraganore DM, Farrer MJ; Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. Ann Neurol. 2011 May;69(5):778-92.

1575 Elefsinioti A, Sarac OS, Hegele A, Plake C, Hubner NC, Poser I, Sarov M, Hyman A, Mann M, Schroeder M, Stelzl U, Beyer A. Large-scale de novo prediction of physical protein-protein association. Mol Cell Proteomics. 2011 Nov;10(11):M111.010629.

1574 Elling, U., Taubenschmid, J., Wirnsberger, G., O'Malley, R., Demers, S.-P., Vanhaelen, Q., Shukalyuk, A.I., Schmauss, G., Schramek, D., Schnütgen, F., von Melchner, H., Ecker, J.R., Stanford, W.L., Zuber, J., Stark, A., and Penninger, J.M. Forward and Reverse Genetics through Derivation of Haploid Mouse Embryonic Stem Cells. Cell Stem Cell 9, 563-547

1573 Ellinghaus E, Stuart PE, Ellinghaus D, Nair RP, Debrus S, Raelson JV, Belouchi M, Tejasvi T, Li Y, Tsoi LC, Onken AT, Esko T, Metspalu A, Rahman P, Gladman DD, Bowcock AM, Helms C, Krueger GG, Koks S, Kingo K, Gieger C, Wichmann HE, Mrowietz U, Weidinger S, Schreiber S, Abecasis GR, Elder JT, Weichenthal M, Franke A. Genome-wide meta-analysis of psoriatic arthritis identifies susceptibility locus at REL. J Invest Dermatol. 2011

1572 Emig D, Albrecht M. Tissue-specific proteins and functional implications. J Proteome Res. 2011 Apr 1;10(4):1893-903.

1571 Emig D, Sander O, Mayr G, Albrecht M. Structure collisions between interacting proteins. PLoS One. 2011;6(6):e19581.

1570 EPICURE Consortium, Leu C, de Kovel CG, Zara F, Striano P, Pezzella M, Robbiano A, Bianchi A, Bisulli F, Coppola A, Giallonardo AT, Beccaria F, Trenité DK, Lindhout D, Gaus V, Schmitz B, Janz D, Weber YG, Becker F, Lerche H, Kleefuss-Lie AA, Hallman K, Kunz WS, Elger CE, Muhle H, Stephani U, Møller RS, Hjalgrim H, Mullen S, Scheffer IE, Berkovic SF, Everett KV, Gardiner MR, Marini C, Guerrini R, Lehesjoki AE, Siren A, Nabbout R, Baulac S, Leguern E, Serratosa JM, Rosenow F, Feucht M, Unterberger I, Covanis A, Suls A, Weckhuysen S, Kaneva R, Caglayan H, Turkdogan D, Baykan B, Bebek N, Ozbek U, Hempelmann A, Schulz H, Rüschendorf F, Trucks H, Nürnberg P, Avanzini G, Koeleman BP, Sander T. Genome-wide linkage meta-analysis identifies susceptibility loci at 2q34 and 13q31.3 for genetic generalized epilepsies. Epilepsia. 2012 Feb;53(2):308-18. Epub 2012 Jan 13.

1569 Eppert K, Takenaka K, Lechman ER, Waldron L, Nilsson B, van Galen P, Metzeler KH, Poeppl A, Ling V, Beyene J, Canty AJ, Danska JS, Bohlander SK, Buske C, Minden MD, Golub TR, Jurisica I, Ebert BL, Dick JE. Stem cell gene expression programs influence clinical outcome in human leukemia. Nat Med. 2011 Aug 28;17(9):1086-93. doi: 10.1038/nm.2415.

1568 Erdmann E, Rupprecht V, Matthews E, Kukley M, Schoch S, Dietrich D. Depression of Release by mGluR8 Alters Ca2+ Dependence of Release Machinery. Cereb Cortex. 2011 Sep 7. [Epub ahead of print] PMID: 21903594

1567 Erdmann J, Willenborg C, Nahrstaedt J, Preuss M, König IR, Baumert J, Linsel-Nitschke P, Gieger C, Tennstedt S, Belcredi P, Aherrahrou Z, Klopp N, Loley C, Stark K, Hengstenberg C, Bruse P, Freyer J, Wagner AK, Medack A, Lieb W, Grosshennig A, Sager HB, Reinhardt A, Schäfer A, Schreiber S, El Mokhtari NE, Raaz-Schrauder D, Illig T, Garlichs CD, Ekici AB, Reis A, Schrezenmeir J, Rubin D, Ziegler A, Wichmann HE, Doering A, Meisinger C, Meitinger T, Peters A, Schunkert H. Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23. Eur Heart J. 2011 Jan;32(2):158-68.

1566 Erhard, F. and R. Zimmer. Classification of ncRNAs using position and size information in deep sequencing data. Bioinformatics. 26: 18.

1565 Erk S, Meyer-Lindenberg A, Opitz von Boberfeld C, Esslinger C, Schnell K, Kirsch P, Mattheisen M, Mühleisen TW, Cichon S, Witt SH, Rietschel M, Nöthen MM, Walter H. Hippocampal function in healthy carriers of the CLU Alzheimer's disease risk variant. J Neurosci. 2011 Dec 7;31(49):18180-4

1564 Erkan M, Reiser-Erkan C, Michalski CW, Kong B, Esposito I, Friess H, Kleeff J. The impact of the activated stroma on pancreatic ductal adenocarcinoma biology and therapy resistance. Curr Mol Med. 2012;12(3):288-303.Erkan M, Adler G, Apte MV, Bachem MG, Buchholz M, Detlefsen S, Esposito I, Friess H, Gress TM, Habisch HJ, Hwang RF, Jaster R, Kleeff J, Klöppel G, Kordes C, Logsdon CD, Masamune A, Michalski CW, Oh J, Phillips PA, Pinzani M, Reiser-Erkan C, Tsukamoto H, Wilson J. StellaTUM: current consensus and discussion on pancreatic stellate cell research. Gut. 2012;61(2):172-8.

1563 Ernst A, Aigner M, Nakata S, Engel F, Schlotter M, Kloor M, Brand K, Schmitt S, Steinert G, Rahbari N, Koch M, Radlwimmer B, Weitz J, Lichter P. A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors. Pathology. 2011 Apr;43(3):220-7.

1562 Esslinger C, Kirsch P, Haddad L, Mier D, Sauer C, Erk S, Schnell K, Arnold C, Witt SH, Rietschel M, Cichon S, Walter H, Meyer-Lindenberg A. Cognitive state and connectivity effects of the genome-wide significant psychosis variant in ZNF804A. Neuroimage. 2011 Feb 1;54(3):2514-2. doi.org/10.1016/j.neuroimage.2010.10.012

1561 Eyerich S, Onken AT, Weidinger S, Franke A, Nasorri F, Pennino D, Grosber M, Pfab F, Schmidt-Weber CB, Mempel M, Hein R, Ring J, Cavani A, Eyerich K. Mutual antagonism of T cells causing psoriasis and atopic eczema. N Engl J Med 2011; 365:231-8

1560 Feagan BG, Hanauer SB, Coteur G, Schreiber S. Evaluation of a daily practice composite score for the assessment of Crohn's disease: the treatment impact of certolizumab pegol. Aliment Pharmacol Ther. 2011 May;33(10):1143-51. doi: 10.1111/j.1365-2036.2011.04636.x. Epub 2011 Mar 28

1559 Fenzl T, Romanowski CP, Flachskamm C, Deussing JM, Kimura M. Wake-promoting effects of orexin: Its independent actions against the background of an impaired corticotropine-releasing hormone receptor system. Behav Brain Res. 2011 Sep 12;222(1):43-50. Epub 2011 Mar 21.

1558 Fiaschetti G, Castelletti D, Zoller S, Schramm A, Schroeder C, Nagaishi M,Stearns D, Mittelbronn M, Eggert A, Westermann F, Ohgaki H, Shalaby T, Pruschy M, Arcaro A, Grotzer MA. Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma. Oncogene. 2011 Feb 14. [Epub ahead of print]

1557 Filipiak-Pittroff B, Schnopp C, Berdel D, Naumann A, Sedlmeier S, Onken A, Rodriguez E, Fölster-Holst R, Baurecht H, Ollert M, Ring J, Cramer C, von Berg A, Bauer CP, Herbarth O, Lehmann I, Schaaf B, Koletzko S,Wichmann HE, Heinrich J, Weidinger S. Predictive value of food sensitization and filaggrin mutations in children with eczema. J Allergy Clin Immunol 2011; 128:1235-1241

1556 Fischer T, Faus-Kessler T, Welzl G, Simeone A, Wurst W, Prakash N. Fgf15-mediated control of neurogenic and proneural gene expression regulates dorsal midbrain neurogenesis. Dev Biol. 2011 Feb 15;350(2):496-510. Epub 2010 Dec 21.

1555 Fischer-Posovszky P, Keuper M, Nagel S, Hesse D, Schürmann A, Debatin KM, Strauss G, Wabitsch M. Downregulation of FLIP by cycloheximide sensitizes human fat cells to CD95-induced apoptosis. Exp Cell Res. 317:2200-2209 (2011).

1554 Fitzgerald JC, Wu SH, Dunn L, Krüger R, Martins LM, Wood NW, Plun-Favreau H. Phosphorylation of HtrA2 by cyclin dependent kinase 5 modulates its neuroprotective function. Cell Death Differ. 2012 Feb;19(2):257-66. doi: 10.1038/cdd.2011.90. Epub 2011 Jun 24

1553 Föcker M, Timmesfeld N, Scherag S, Bühren K, Langkamp M, Dempfle A, Sheridan EM, de Zwaan M, Fleischhaker C, Herzog W, Egberts K, Zipfel S, Herpertz-Dahlmann B, Hebebrand J. Screening for anorexia nervosa via measurement of serum leptin levels. J Neural Transm. 2011 Apr;118(4):571-8. Epub 2011 Jan 22. PubMed PMID: 21258826.

1552 Fong CY, Rolfs A, Schwarzbraun T, Klein C, O'Callaghan FJ. Juvenile parkinsonism associated with heterozygous frameshift ATP13A2 gene mutation. Eur J Paediatr Neurol 2011.

1551 Fontaine, J.F., F. Priller, A. Barbosa-Silva, M.A. Andrade-Navarro. 2011. Génie: literature-based gene prioritization at multi genomic scale. Nucleic Acids Research. 39:W455-W461.

1550 Fox ER, Young JH, Li Y, Dreisbach AW, Keating BJ, Musani SK, Liu K, Morrison AC, Ganesh S, Kutlar A, Ramachandran VS, Polak JF, Fabsitz RR, Dries DL, Farlow DN, Redline S, Adeyemo A, Hirschorn JN, Sun YV, Wyatt SB, Penman AD, Palmas W, Rotter JI, Townsend RR, Doumatey AP, Tayo BO, Mosley TH Jr, Lyon HN, Kang SJ, Rotimi CN, Cooper RS, Franceschini N, Curb JD, Martin LW, Eaton CB, Kardia SL, Taylor HA, Caulfield MJ, Ehret GB, Johnson T; International Consortium for Blood Pressure Genome-wide Association Studies (ICBP-GWAS), Chakravarti A, Zhu X, Levy D, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt T, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund P, Kuznetsova T, Uiterwaal CS, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND, CARDIoGRAM consortium, CKDGen consortium, KidneyGen consortium, EchoGen consortium, CHARGE-HF consortium, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Collins R, Hopewell JC, Ongen H, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Hoffman Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Soler Artigas M, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi J, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stancáková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell C, Schwartz SM, Ikram MA, Longstreth WT Jr, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries S, Danesh J, Rasheed A, oel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MJ, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Wong TY, Tai ES, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, Boerwinkle E, Boehnke M, Larson MG, Järvelin MR, Psaty BM, Abecasis GR, Elliott P, van Duijn C, Newton-Cheh C. Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study. Hum Mol Genet. 2011

1549 Frank J, Cichon S, Treutlein J, Ridinger M, Mattheisen M, Wodarz N, Soyka M, Zill P,  Maier W, Gaebel W, Dahmen N, Scherbaum N, Schmäl C, Priebe L, Steffens M, Müller-Myhsok B, Nöthen M, Mann K, Kiefer F, Rietschel M (2012). Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster. Addiction Biology 1:171-180

1548 Frank S, M. Heni, A. Moss, J. von Schnurbein, A. Fritsche, H.U. Haring, S. Farooqi, H. Preissl, and M. Wabitsch. Leptin Therapy in a Congenital Leptin-Deficient Patient Leads to Acute and Long-Term Changes in Homeostatic, Reward, and Food-Related Brain Areas. J Clin Endocrinol Metab. 96(8):1283-1287 (2011).

1547 Freiwald A, Mao L, Kodelja V, Kliem M, Schuldt D, Schreiber S, Franke A, Sauer S. Differential analysis of Crohn?s disease and ulcerative colitis by mass spectrometry. Inflamm Bowel Dis 2011 Apr;17(4):1051-1052.

1546 Fröhlich G, Pott W, Albayrak Ö, Hebebrand J, Pauli-Pott U. Conditions of long-term success in a lifestyle intervention for overweight and obese youths. Pediatrics. 2011 Oct;128(4):e779-85. Epub 2011 Sep 12. PubMed PMID: 21911346.

1545 Fromme T and Klingenspor M. Uncoupling protein 1 expression and high fat diets. Am J Physiol Regul Integr Comp Physiol. 2011 Jan; 300(1):R1-8

1544 Fuchs H, Gailus-Durner V, Adler T, Aguilar-Pimentel JA, Becker L, Calzada-Wack J, Da Silva-Buttkus P, Neff F, Götz A, Hans W, Hölter SM, Horsch M, Kastenmüller G, Kemter E, Lengger C, Maier H, Matloka M, Möller G, Naton B, Prehn C, Puk O, Rácz I, Rathkolb B, Römisch-Margl W, Rozman J, Wang-Sattler R, Schrewe A, Stöger C, Tost M, Adamski J, Aigner B, Beckers J, Behrendt H, Busch DH, Esposito I, Graw J, Illig T, Ivandic B, Klingenspor M, Klopstock T, Kremmer E, Mempel M, Neschen S, Ollert M, Schulz H, Suhre K, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M: Mouse phenotyping. Methods. 53, 120-135 (2011) doi:10.1016/j.ymeth.2010.08.006

1543 Gade S, Porzelius C, Faelth M, Brase JC, Wuttig D, Kuner R, Binder H, Sültmann H, Beissbarth T. Graph based fusion of miRNA and mRNA expression data improves clinical outcome prediction in prostate cancer. BMC Bioinformatics. 2011;12:488

1542 Gaertner J, Wolf J, Frechen S, Klein U, Scheicht D, Hellmich M, Toepelt K, Glossmann JP,  Ostgathe C, Hallek M, Voltz R. Recommending early integration of palliative care - does it work? Support Care Cancer. 2012 Mar;20(3):507-13. Epub 2011 Feb 19.

1541 Gaertner J, Wuerstlein R, Klein U, Scheicht D, Frechen S, Wolf J, Hellmich M, Mallmann P, Harbeck N, Voltz R. Integrating Palliative Medicine into Comprehensive Breast Cancer Therapy - a Pilot Project. Breast Care (Basel). 2011;6(3):215-220. Epub 2011 Jun 14.

1540 Gajula Balija MB, Griesinger C, Herzig A, Zweckstetter M, Jäckle H. Pre-fibrillar ?-synuclein mutants cause Parkinson's disease-like non-motor symptoms in Drosophila. PLoS One. 2011;6(9):e24701. Epub 2011 Sep 8.

1539 Ganguly K, Upadhyay S, Irmler M, Takenaka S, Pukelsheim K, Beckers J, De Angelis MH, Hamelmann E, Stoeger T, Schulz H. Impaired resolution of inflammatory response in the lungs of JF1/Msf mice following carbon nanoparticle instillation. Respir Res. 2011 Jul 15;12:94. DOI: 10.1186/1465-9921-12-94

1538 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Extent of pre-operative L-DOPA-induced dyskinesia predicts the severity of graft-induced dyskinesia after fetal dopamine cell transplantation. Exp Neurol. 2011 Dec;232(2):270-9. Epub 2011 Sep 17. doi:10.1016/j.expneurol.2011.09.017

1537 García J, Carlsson T, Döbrössy M, Nikkhah G, Winkler C. Impact of dopamine to serotonin cell ratio in transplants on behavioral recovery and L-DOPA-induced dyskinesia. Neurobiol Dis. 2011 Sep;43(3):576-87. Epub 2011 May 13. doi:10.1016/j.nbd.2011.05.004

1536 Garshasbi M, Kahrizi K, Hosseini M, Nouri Vahid L, Falah M, Hemmati S, Hu H, Tzschach A, Ropers HH, Najmabadi H, Kuss AW. A novel nonsense mutation in TUSC3 is responsible for non-syndromic autosomal recessive mental retardation in a consanguineous Iranian family. Am J Med Genet A. 2011 Aug;155A(8):1976-80. doi: 10.1002/ajmg.a.34077. Epub 2011 Jul 7.

1535 Garvalov B, Acker T. Cancer stem cells: a new framework for the design of tumor therapies. J Mol Med (Berl). 2011 Feb;89(2):95-107. Epub 2010 Oct 2.

1534 Gasser T. Identifying PD-causing genes and genetic susceptibility factors: current approaches and future prospects. Progress in Brain research. Recent Advances in Parkinson's DiseasePart I: Basic Research

1533 Geistlinger, L., G. Csaba, R. Küffner, N. Mulder, R. Zimmer. From Sets to Graphs: Towards a Realistic Enrichment Analysis of Transcriptomic Systems. Bioinformatics (2011) 27 (13): i366-i373. doi: 10.1093/bioinformatics/btr228

1532 Gerber JC, Neuhann, TM, Tyshchenko N, Smitka M, Hackmann K. Expanding the Clinical and Neuroradiological Phenotype of 6q27 Microdeletion: Olfactory Bulb Aplasia and Anosmia. Am J Med Genet. A 2011, 155A: 1981-1986 PMID 21744487

1531 German IBD Study Group. [Adherence to the H1N1 vaccination recommendation in patients with Crohn's disease or ulcerative colitis]. Dtsch Med Wochenschr. 2011 May;136(18):939-43. Epub 2011 May 2.

1530 Gessi M, Setty P, Bisceglia M, zur Muehlen A, Lauriola L, Waha A, Giangaspero F, Pietsch T. Supratentorial primitive neuroectodermal tumors of the central nervous system in adults: molecular and histopathologic analysis of 12 cases. Am J Surg Pathol. 2011 Apr;35(4):573-82.

1529 Gessi M, Waha A, Setty P, Waha A, Pietsch T. Analysis of KIAA1549-BRAF fusion status in a case of rosette-forming glioneuronal tumor of the fourth ventricle (RGNT). Neuropathology. 2011 Apr 26. doi: 10.1111/j.1440-1789.2011.01220

1528 Gieger C, Radhakrishnan A, Cvejic A, Tang W, Porcu E, Pistis G, Serbanovic-Canic J, Elling U, Goodall AH, Labrune Y, Lopez LM, Mägi R, Meacham S, Okada Y, Pirastu N, Sorice R, Teumer A, Voss K, Zhang W, Ramirez-Solis R, Bis JC, Ellinghaus D, Gögele M, Hottenga JJ, Langenberg C, Kovacs P, O'Reilly PF, Shin SY, Esko T, Hartiala J, Kanoni S, Murgia F, Parsa A, Stephens J, van der Harst P, Ellen van der Schoot C, Allayee H, Attwood A, Balkau B, Bastardot F, Basu S, Baumeister SE, Biino G, Bomba L, Bonnefond A, Cambien F, Chambers JC, Cucca F, D'Adamo P, Davies G, de Boer RA, de Geus EJ, Döring A, Elliott P, Erdmann J, Evans DM, Falchi M, Feng W, Folsom AR, Frazer IH, Gibson QD, Glazer NL, Hammond C, Hartikainen AL, Heckbert SR, Hengstenberg C, Hersch M, Illig T, Loos RJ, Jolley J, Tee Khaw K, Kühnel B, Kyrtsonis MC, Lagou V, Lloyd-Jones H, Lumley T, Mangino M, Maschio A, Mateo Leach I, McKnight B, Memari Y, Mitchell BD, Montgomery GW, Nakamura Y, Nauck M, Navis G, Nöthlings U, Nolte IM, Porteous DJ, Pouta A, Pramstaller PP, Pullat J, Ring SM, Rotter JI, Ruggiero D, Ruokonen A, Sala C, Samani NJ, Sambrook J, Schlessinger D, Schreiber S, Schunkert H, Scott J, Smith NL, Snieder H, Starr JM, Stumvoll M, Takahashi A, Tang WH, Taylor K, Tenesa A, Lay Thein S, Tönjes A, Uda M, Ulivi S, van Veldhuisen DJ, Visscher PM, Völker U, Wichmann HE, Wiggins KL, Willemsen G, Yang TP, Hua Zhao J, Zitting P, Bradley JR, Dedoussis GV, Gasparini P, Hazen SL, Metspalu A, Pirastu M, Shuldiner AR, Joost van Pelt L, Zwaginga JJ, Boomsma DI, Deary IJ, Franke A, Froguel P, Ganesh SK, Jarvelin MR, Martin NG, Meisinger C, Psaty BM, Spector TD, Wareham NJ, Akkerman JW, Ciullo M, Deloukas P, Greinacher A, Jupe S, Kamatani N, Khadake J, Kooner JS, Penninger J, Prokopenko I, Stemple D, Toniolo D, Wernisch L, Sanna S, Hicks AA, Rendon A, Ferreira MA, Ouwehand WH, Soranzo N. New gene functions in megakaryopoiesis and platelet formation. Nature. 2011 Nov 30 ;480(7376):201-8.

1527 Giegling I, Drago A, Dol?an V, Plesni?ar BK, Schäfer M, Hartmann AM, Sander T, Toliat MR, Möller HJ, Stassen HH, Rujescu D, Serretti A. Glutamatergic gene variants impact the clinical profile of efficacy and side effects of haloperidol. Pharmacogenet Genomics 2011 Apr;21(4):206-16.

1526 Giegling I, Drago A, Schäfer M, Hartmann AM, Sander T, Toliat MR, Möller HJ, De Ronchi D, Stassen HH, Rujescu D, Serretti A. Lack of association between 71 variations located in candidate genes and response to acute haloperidol treatment. Psychopharmacology (Berl). 2011 Apr;214(3):719-28. Epub 2010 Nov 16.

1525 Gilbert DF, Erdmann G, Zhang X, Fritzsche A, Demir K, Jaedicke A, Muehlenberg K, Wanker EE, Boutros M. A novel multiplex cell viability assay for high-throughput RNAi screening. PLoS One. 2011;6(12):e28338. doi:10.1371/journal.pone.0028338

1524 Gilling M, Lind-Thomsen A, Mang Y, Bak M, Møller M, Ullmann R, Kristoffersson U, Kalscheuer VM, Henriksen KF, Bugge M, Tümer Z, Tommerup N. Biparental inheritance of chromosomal abnormalities in male twins with non-syndromic mental retardation. Eur J Med Genet. 2011 Mar 21. [Epub ahead of print]

1523 Glaser C, Rzehak P, Demmelmair H, Klopp N, Heinrich J, Koletzko B; LISA study group. Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children. PLoS One  2011

1522 Goidts V, Bageritz J, Puccio L, Nakata S, Zapatka M, Barbus S, Toedt G, Campos B, Korshunov A, Momma S, Van Schaftingen E, Reifenberger G, Herold-Mende C, Lichter P, Radlwimmer B. RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival. Oncogene. 2012 Jul 5;31(27):3235-43. doi: 10.1038/onc.2011.490. Epub 2011 Nov 7.

1521 Gonzalez, O. and R. Zimmer. Contextual Analysis of RNAi-based Functional Screens Using Interaction Networks.' Bioinformatics. 2011 Oct 1;27(19):2707-13. Epub 2011 Aug 10.

1520 Good DM, Zürbig P, Argilés A, Bauer HW, Behrens G, Coon JJ, Dakna M, Decramer S, Delles C, Dominiczak AF, Ehrich JH, Eitner F, Fliser D, Frommberger M, Ganser A, Girolami MA, Golovko I, Gwinner W, Haubitz M, Herget-Rosenthal S, Jankowski J, Jahn H, Jerums G, Julian BA, Kellmann M, Kliem V, Kolch W, Krolewski AS, Luppi M, Massy Z, Melter M, Neusüss C, Novak J, Peter K, Rossing K, Rupprecht H, Schanstra JP, Schiffer E, Stolzenburg JU, Tarnow L, Theodorescu D, Thongboonkerd V, Vanholder R, Weissinger EM, Mischak H, Schmitt-Kopplin P. Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease. Mol Cell Proteomics. 2010 Nov;9(11)

1519 Götz AA, Rozman J, Rödel HG, Fuchs H, Gailus-Durner V, Hrab? de Angelis M, Klingenspor M and Stöger T. Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets. Particle and Fibre Toxicology Volume: 8:30. DOI:10.1186/1743-8977-8-30

1518 Götz AA, Vidal-Puig A, Rödel HG, Hrabé de Angelis M, Stoeger T. Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARg-defective (P465L) mice. Particle and Fibre Toxicology 2011, 8:28 DOI:10.1186/1743-8977-8-28

1517 Grabe HJ, Mahler J, Witt SH, Schulz A, Appel K, Spitzer C, Stender J, Barnow S, Freyberger HJ, Teumer A, Völzke H, Rietschel M. A risk marker for alcohol dependence on chromosome 2q35 is related to neuroticism in the general population. Mol Psychiatry. 2011 Feb;16(2):126-8.

1516 Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, Hoermann P, Ebner R, Becker H, Difilippantonio MJ, Ghadimi BM, Beissbarth T, Caplen NJ, Ried T. A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets. Int J Cancer. 2011; 128(5):1069-79.

1515 Grallert H, Dupuis J, Bis JC, Dehghan A, Barbalic M, Baumert J, Lu C, Smith NL, Uitterlinden AG, Roberts R, Khuseyinova N, Schnabel RB, Rice KM, Rivadeneira F, Hoogeveen RC, Fontes JD, Meisinger C, Keaney JF Jr, Lemaitre R, Aulchenko YS, Vasan RS, Ellis S, Hazen SL, van Duijn CM, Nelson JJ, März W, Schunkert H, McPherson RM, Stirnadel-Farrant HA, Psaty BM, Gieger C, Siscovick D, Hofman A, Illig T, Cushman M, Yamamoto JF, Rotter JI, Larson MG, Stewart AF, Boerwinkle E, Witteman JC, Tracy RP, Koenig W, Benjamin EJ, Ballantyne CM. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. Eur Heart J. 2012 Jan;33(2):238-51. Epub 2011 Oct 14.

1514 Grasshoff U, Bonin M, Goehring I, Ekici A, Dufke A, Cremer K, Wagner N, Rossier E, Jauch A, Walter M, Bauer C, Bauer P, Horber K, Beck-Woedl S, Wieczorek D. (2011). De novo MECP2 duplication in two females with random X-inactivation and moderate mental retardation. Eur J Hum Genet. 2011 May;19(5):507-12. Epub 2011 Feb 16.doi:10.1038/ejhg.2010.226

1513 Gregor A, Albrecht B, Bader I, Bijlsma EK, Ekici AB, Engels H, Hackmann K, Horn D, Hoyer J, Klapecki J, Kohlhase J, Maystadt I, Nagl S, Prott E, Tinschert S, Ullmann R, Wohlleber E, Woods G, Reis A, Rauch A, Zweier C. Expanding the clinical spectrum associated with defects in CNTNAP2 and NRXN1. BMC Med Genet. 2011 Aug 9;12:106. PMID:21827697

1512 Greif PA, Eck SH, Konstandin NP, Benet-Pagès A, Ksienzyk B, Dufour A, Vetter AT, Popp HD, Lorenz-Depiereux B, Meitinger T, Bohlander SK*, Strom TM*.  * joint senior authors. Identification of recurring tumor-specific somatic mutations in acute myeloid leukemia by transcriptome sequencing.Leukemia. 2011;25:821-827

1511 Greif PA, Yaghmaie M, Konstandin N, Ksienzyk B, Alimoghaddam K, Ghavamzadeh A, Hauser A, Graf A, Krebs S, Blum H, Bohlander SK. Somatic mutations in acute promyelocytic leukemia (APL) identified by exome sequencing. Leukemia. 2011;25:1519-1522.

1510 Grelle G, Otto A, Lorenz M, Frank RF, Wanker EE, Bieschke J. Black tea theaflavins inhibit formation of toxic amyloid-? and ?-synuclein fibrils. Biochemistry. 2011 Dec 13;50(49):10624-36. Epub 2011 Nov 16.

1509 Gremer L, Merbitz-Zahradnik T, Dvorsky R, Cirstea IC, Kratz CP, Zenker M, Wittinghofer A,  Ahmadian MR. Impacts of germline mutations in KRAS on the GTPase cycle and effector interaction. Hum Mutat 32, 33-43. PMID: 20949621

1508 Gress TM, Kestler HA, Lausser L, Fiedler L, Sipos B, Michalski CW, Werner J, Giese N, Scarpa A, Buchholz M. Differentiation of multiple types of pancreatico-biliary tumors by molecular analysis of clinical specimens. J Mol Med (Berl). 2012 Apr;90(4):457-64. Epub 2011 Nov 26.

1507 Grimm MO, Grösgen S, Riemenschneider M, Tanila H, Grimm HS, Hartmann T. From brain to food: analysis of phosphatidylcholins, lyso-phosphatidylcholins and phosphatidylcholin-plasmalogens derivates in Alzheimer's disease human post mortem brains and mice model via mass spectrometry. J Chromatogr A. 2011;1218(42):7713-22.

1506 Grimm MO, Kuchenbecker J, Grosgen S, Burg VK, Hundsdorfer B, Rothhaar TL, Friess P, de Wilde MC, Broersen LM, Penke B, Peter M, Vigh L, Grimm HS, Hartmann T. Docosahexaenoic acid reduces amyloid beta production via multiple pleiotropic mechanisms. J Biol Chem 286:14028-14039.

1505 Grimm MO, Kuchenbecker J, Rothhaar TL, Grosgen S, Hundsdorfer B, Burg VK, Friess P, Muller U, Grimm HS, Riemenschneider M, Hartmann T. Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease. J Neurochem 116:916-925.

1504 Grimm MO, Rothhaar TL, Grosgen S, Burg VK, Hundsdorfer B, Haupenthal VJ, Friess P, Kins S, Grimm HS, Hartmann T. Trans fatty acids enhance amyloidogenic processing of the Alzheimer amyloid precursor protein (APP). J Nutr Biochem.

1503 Grimm MO, Rothhaar TL, Hartmann T. The role of APP proteolytic processing in lipid metabolism. Exp Brain Res.

1502 Gronych J, Korshunov A, Bageritz J, Milde T, Jugold M, Hambardzumyan D, Remke M, Hartmann C, Witt H, Jones DT, Witt O, Heiland S, Bendszus M, Holland EC, Pfister S, Lichter P. An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice.J Clin Invest. 2011 Apr 1;121(4):1344-1348. doi: 10.1172/JCI44656.

1501 Gross A, Tönjes A, Kovacs P, Veeramah KR, Ahnert P, Roshyara NR, Gieger C, Rueckert IM, Loeffler M, Stoneking M, Wichmann HE, Novembre J, Stumvoll M, Scholz M. Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays. BMC Genet. 2011

1500 Grünewald A, Voges L, Rakovic A, Kasten M, Vandebona H, Hemmelmann C, Lohmann K, Orolicki S, Ramirez A, Schapira AHV, Pramstaller PP, Sue CM, Klein C. Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts. PLoS One 2010; 5:e12962.

1499 Günther T, Schmitt AO, Bortfeldt RH, Hinney A, Hebebrand J, Brockmann GA. Where in the genome are significant single nucleotide polymorphisms from genome-wide association studies located? OMICS. 2011 Jul-Aug;15(7-8):507-12. doi: 10.1089/omi.2010.0154. Epub 2011 Jun 23. PubMed PMID: 21699402.

1498 Haas J, Katus HA, Meder B. Next-generation sequencing entering the clinical arena. Mol Cell Probes. 2011 Sep 8. [Epub ahead of print].

1497 Halenius A, Hauka S, Dölken L, Stindt J, Reinhard H, Wiek C, Hanenberg H, Koszinowski UH, Momburg F, Hengel H. Human cytomegalovirus disrupts the major histocompatibility complex class I Peptide-loading complex and inhibits tapasin gene transcription. J Virol. 2011 Apr;85(7):3473-85. Epub 2011 Jan 19.

1496 Hallen L., Klein H., Stoschek C., Wehrmeyer S., Nonhoff U., Ralser M., Wilde J., Röhr C., Schweiger M.R., Zatloukal K., Vingron M., Lehrach H., Konthur Z. and S. Krobitsch. The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Hum Mol Genet. 2011 Jan 1;20(1):104-14.

1495 Hann A, Gruner A, Chen Y, Gress TM, and Buchholz M. Comprehensive analysis of cellular galectin-3 reveals no consistent oncogenic function in pancreatic cancer cells. PLoS One. 2011;6(6):e20859. Epub 2011 Jun 16.

1494 Hansen T, Ingason A, Djurovic S, Melle I, Fenger M, Gustafsson O, Jakobsen KD, Rasmussen HB, Tosato S, Rietschel M, Frank J, Owen M, Bonetto C, Suvisaari J, Thygesen JH, Pétursson H, Lönnqvist J, Sigurdsson E, Giegling I, Craddock N, O'Donovan MC, Ruggeri M, Cichon S, Ophoff RA, Pietiläinen O, Peltonen L, Nöthen MM, Rujescu D, St Clair D, Collier DA, Andreassen OA, Werge T. At-Risk Variant in TCF7L2 for Type II Diabetes Increases Risk of Schizophrenia. Biol Psychiatry. 2011 Mar 15. [Epub ahead of print]

1493 Hantschel C, Wagener A, Neuschl C, Teupser D, Brockmann GA. Features of the metabolic syndrome in the Berlin Fat Mouse as a model for human obesity. Obes Facts 2011; 4(4):270-277

1492 Hao, W., Y. Liu, S. Liu, S. Walter, M.O. Grimm, A. J. Kiliaan, B. Penke, T. Hartmann,C.E. Rübe, M.D. Menger, K. Fassbender. Myeloid differentiation factor 88-deficient bone marrow cells improve Alzheimer's disease-related symptoms andpathology. Brain. 2011 Jan;134(Pt 1):278-92. Epub 2010 Nov 28.

1491 Hartmann T, Prinetti A. Going the wrong road: Fyn and targeting of amyloid precursor protein to lipid rafts. J Neurochem 118:677-679.

1490 Häsler R, Kerick M, Mah N, Hultschig C, Richter G, Bretz F, Sina C, Lehrach H, Nietfeld W,
Schreiber S, Rosenstiel P. Alterations of pre-mRNA splicing in human inflammatory bowel disease. Eur J Cell Biol. 2011 Feb 14. [Epub ahead of print]PubMed PMID: 21324547.

1489 Håvik B, Le Hellard S, Rietschel M, Lybæk H, Djurovic S, Mattheisen M, Mühleisen TW, Degenhardt F, Priebe L, Maier W, Breuer R, Schulze TG, Agartz I, Melle I, Hansen T, Bramham CR, Nöthen MM, Stevens B, Werge T, Andreassen OA, Cichon S, Steen VM: The Complement Control-Related Genes CSMD1 and CSMD2 Associate to Schizophrenia. Biol Psychiatry. 70:35-42, 2011. DOI: 10.1016/j.biopsych.2011.01.030

1488 Haworth A, Bertram L, Carrera P, Elson JL, Braastad CD, Cox DW, Cruts M, den Dunnen JT, Farrer MJ, Fink JK, Hamed SA, Houlden H, Johnson DR, Nuytemans K, Palau F, Rayan DL, Robinson PN, Salas A, Schüle B, Sweeney MG, Woods MO, Amigo J, Cotton RG, Sobrido MJ. Call for participation in the neurogenetics consortium within the Human Variome Project. Neurogenetics 12(3):169-73.

1487 Hebebrand J, Buitelaar JK. On the way to DSM-V. Eur Child Adolesc Psychiatry.2011 Feb;20(2):57-60. PubMed PMID: 21267613; PubMed Central PMCID: PMC3038228.

1486 Hebebrand J, Bulik CM. Critical appraisal of the provisional DSM-5 criteria for anorexia nervosa and an alternative proposal. Int J Eat Disord. 2011 Dec;44(8):665-78. doi: 10.1002/eat.20875. Epub 2010 Nov 15. PubMed PMID:22072403.

1485 Hebebrand J. Pharmacotherapy of anorexia nervosa: more questions than answers. J Am Acad Child Adolesc Psychiatry. 2011 Sep;50(9):854-6. PubMed PMID: 21871366.

1484 Heck A, Pfister H, Czamara D, Müller-Myhsok B, Pütz B, Lucae S, Hennings J,Ising M. Evidence for associations between MDGA2 polymorphisms and harmavoidance: replication and extension of a genome-wide association finding. Psychiatr Genet. 2011 Oct;21(5):257-60. doi: 10.1097/YPG.0b013e3283457bfb

1483 Heid I, Lubeseder-Martellato C, Sipos B, Mazur PK, Lesina M, Schmid RM, Siveke JT. Early requirement of Rac1 in a mouse model of pancreatic cancer. Gastroenterology. 2011;141:719-30.

1482 Heinz AJ, Beck A, Meyer-Lindenberg A, Sterzer P, Heinz A: Cognitive and neurobiological mechanisms of alcohol-related aggression. Nat Rev Neurosci. 12(7):400-13 (2011)

1481 Helinski S, Spanagel R (2011). Publication trends in addiction research. Addict Biol 16:532-539

1480 Helling S, Shinde S, Brosseron F, Schnabel A, Mu?ller T, Meyer HE, Marcus K, Sellergren B.Ultratrace Enrichment of Tyrosine Phosphorylated Peptides on an Imprinted Polymer. Anal Chem. 2011 Feb 9. [Epub ahead of print] PMID:    21306124

1479 Hellmann JK, Münter S, Kudryashev M, Schulz S, Heiss K, Müller AK, Matuschewski K, Spatz JP, Schwarz US, Frischknecht F. Environmental constraints guide migration of malaria parasites during transmission. PLoS Pathogens 2011 Jun; 7:e1002080

1478 Henrich KO, Bauer T, Schulte JH, Ehemann V, Deubzer HE, Gogolin S, Muth D, Fischer M, Benner A, König R, Schwab M, Westermann F. CAMTA1, a 1p36 tumor suppressor candidate, inhibits growth and activates differentiation programmes in neuroblastoma cells. Cancer Res. 2011 Mar 8. [Epub ahead of print]

1477 Herder C, Peeters W, Illig T, Baumert J, de Kleijn DP, Moll FL, Poschen U, Klopp N, Müller-Nurasyid M, Roden M, Preuss M; CARDIoGRAM Consortium, Karakas M, Meisinger C, Thorand B, Pasterkamp G, Koenig W, Assimes TL, Deloukas P, Erdmann J, Holm H, Kathiresan S, König IR, McPherson R, Reilly MP, Roberts R, Samani NJ, Schunkert H, Stewart AF. RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies. PloS One. 2011; 6(12):e25734. Epub 2011 Dec 6.

1476 Hermann D, Weber-Fahr W, Sartorius A, Hoerst M, Frischknecht U, Tunc-Skarka N, Perreau-Lenz S, Hansson AC, Krumm B, Kiefer F, Spanagel R, Mann K, Ende G, Sommer WH (in press 2011). Translational Magnetic Resonance Spectroscopy Reveals Excessive Central Glutamate Levels During Alcohol Withdrawal in Humans and Rats. Biological Psychiatry. 2011 Sep 10. [Epub ahead of print]

1475 Herold T, Jurinovic V, Metzeler KH, Boulesteix AL, Bergmann M, Seiler T, Mulaw M, Thoene S, Dufour A, Pasalic Z, Schmidberger M, Schmidt M, Schneider S, Kakadia PM, Feuring-Buske M, Braess J, Spiekermann K, Mansmann U, Hiddemann W, Buske C, Bohlander SK. An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia. Leukemia. 2011;25:1639-1645.

1474 Herold T, Jurinovic V, Mulaw M, Seiler T, Dufour A, Schneider S, Kakadia PM, Feuring-Buske M, Braess J, Spiekermann K, Mansmann U, Hiddemann W, Buske C, Bohlander SK. Expression analysis of genes located in the minimally deleted regions of 13q14 and 11q22-23 in chronic lymphocytic leukemia-unexpected expression pattern of the RHO GTPase activator ARHGAP20. Genes Chromosomes Cancer. 2011;50:546-558.

1473 Herrmann A, Haake A, Ammerpohl O, Martin-Guerrero I, Szafranski K, Stemshorn K, Nothnagel M, Kotsopoulos SK, Richter J, Warner J, Olson J, Link DR, Schreiber S, Krawczak M, Platzer M, Nürnberg P, Siebert R, Hampe J. Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors. PLoS One. 2011;6(7):e21332. Epub 2011 Jul 5.

1472 Heuckmann, J.M., M. Hölzel, M.L. Sos, S. Heynck, H. Balke-Want, M. Koker, M. Peifer, J. Weiss, C.M. Lovly, C. Grütter, D. Rauh, W. Pao, R.K. Thoma. ALK mutations conferring differential resistance to structurally diverse ALK inhibitors. Clin Cancer Res, 2011, 17(23):7394-401.

1471 Hinney A, Scherag A, Jarick I, Albayrak Ö, Pütter C, Pechlivanis S, Dauvermann MR, Beck S, Weber H, Scherag S, Nguyen TT, Volckmar AL, Knoll N, Faraone SV, Neale BM, Franke B, Cichon S, Hoffmann P, Nöthen MM, Schreiber S, Jöckel KH, Wichmann HE, Freitag C, Lempp T, Meyer J, Gilsbach S, Herpertz-Dahlmann B, Sinzig J, Lehmkuhl G, Renner TJ, Warnke A, Romanos M, Lesch KP, Reif A, Schimmelmann BG, Hebebrand J; Psychiatric GWAS Consortium: Genome-wide association study in German patients with attention deficit/hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(8):888-97. doi: 10.1002/ajmg.b.31246. Epub 2011 Oct 19. PubMed PMID: 22012869.

1470 Hinney A, Scherag S, Hebebrand J. Genetic findings in anorexia and bulimia nervosa. Prog Mol Biol Transl Sci. 2010;94:241-70. doi: 10.1016/S1877-1173(10)94009-X. Review. PubMed PMID: 21036328.

1469 Hippe HJ, Wolf NM, Abu-Taha HI, Lutz S, Le Lay S, Just S, Rottbauer W, Katus HA, Wieland T. Nucleoside diphosphate kinase b is required for the formation of heterotrimeric g protein containing caveolae. Naunyn Schmiedebergs Arch Pharmacol. 2011

1468 Hof J, Krentz S, van Schewick C, Koerner G, Shalapour S, Rhein P, Karawajew L, Seeger K, Henze G, von Stackelberg A, Hagemeier C, Eckert C, Kirschner-Schwabe R. Mutations and deletions of the TP53 gene predict non-response and poor outcome in first relapse of childhood acute lymphoblastic leukemia. J Clin Oncol. 2011 Aug 10;29(23):3185-93. doi 10.1200/JCO.2011.34.8144

1467 Hofemeister, H, Ciotta, G, Fu J, Seibert P, Schulz A, Maresca M, Sarov M, Anastassiadis K and Stewart AF. Recombineering, transfection, Western, IP and ChIP methods for protein tagging via gene targeting or BAC transgenesis. Methods 53, 437-52.

1466 Hofmann S, Fischer A, Till A*, Müller-Quernheim J, Häsler R, Franke A, Gäde K, GenPhenReSa Consortium, Schaarschmidt H, Rosenstiel P, Nebel A, Schürmann M, Nothnagel M, Schreiber S (2011). A genome-wide association study reveals evidence of association with sarcoidosis at 6p12.1.Eur Respir J, 38(5):1127-35.

1465 Höglinger GU, Melhem NM, Dickson DW, Sleiman PM, Wang LS, Klei L, Rademakers R, de Silva R, Litvan I, Riley DE, van Swieten JC, Heutink P, Wszolek ZK, Uitti RJ, Vandrovcova J, Hurtig HI, Gross RG, Maetzler W, Goldwurm S, Tolosa E, Borroni B, Pastor P; PSP Genetics Study Group, Cantwell LB, Han MR, Dillman A, van der Brug MP, Gibbs JR, Cookson MR, Hernandez DG, Singleton AB, Farrer MJ, Yu CE, Golbe LI, Revesz T, Hardy J, Lees AJ, Devlin B, Hakonarson H, Müller U, Schellenberg GD. Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. .Nat Genet. 2011;43:699-705

1464 Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D, Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H, Warden D, Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, Maier W, Jessen F, Rüther E, Schürmann B, Heun R, Kölsch H, van den Bussche H, Heuser I, Kornhuber J, Wiltfang J, Dichgans M, Frölich L, Hampel H, Gallacher J, Hüll M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Mühleisen TW, Nöthen MM, Moebus S, Jöckel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC; Alzheimer's Disease Neuroimaging Initiative, van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S; CHARGE consortium, Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alpérovitch A, Lathrop M; EADI1 consortium, Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, Björnsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel P, Williams J. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet. 2011;43(5):429-35. [Epub 2011]

1463 Holtrup, F., Bauer, A., Fellenberg, K., Hilger, R.A., Wink, M. & Hoheisel, J.D. Nemorosone specifically inhibits growth of pancreatic cancer cells and induces apoptosis via activation of the unfolded protein response (UPR). Brit. J. Pharmacol. 162, 1045-1059 (2011).

1462 Hoppe C, Elger CE. Depression in epilepsy: a critical review from a clinical perspective. Nat Rev Neurol. 2011 Jul 12;7(8):462-72. doi: 10.1038/nrneurol.2011.104. Review. PMID: 21750525

1461 Horsch M, Seeburg PH, Adler T, Aguilar-Pimentel JA, Becker L, Calzada-Wack J, Garrett L, Götz A, Hans W, Higuchi M, Hölter SM, Naton B, Prehn C, Puk O, Rácz I, Rathkolb B, Rozman J, Schrewe A, Adamski J, Busch DH, Esposito I, Graw J, Ivandic B, Klingenspor M, Klopstock T, Mempel M, Ollert M, Schulz H, Wolf E, Wurst W, Zimmer A, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Beckers J. Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice. J Biol Chem. 286(21):18614-22. DOI 10.1074/jbc.M110.200881

1460 Hu H, Eggers K, Chen W, Garshasbi M, Motazacker MM, Wrogemann K, Kahrizi K, Tzschach A, Hosseini M, Bahman I, Hucho T, Mühlenhoff M, Gerardy-Schahn R, Najmabadi H, Ropers HH, Kuss AW. ST3GAL3 mutations impair the development of higher cognitive functions. Am J Hum Genet. 2011 Sep 9;89(3):407-14. doi: 10.1016/j.ajhg.2011.08.008.

1459 Hunt KA, Smyth DJ, Balschun T, Ban M, Mistry V, Ahmad T, Anand V, Barrett JC, Bhaw-Rosun L, Bockett NA, Brand OJ, Brouwer E, Concannon P, Cooper JD, Dias KR, van Diemen CC, Dubois PC, Edkins S, Fölster-Holst R,Fransen K, Glass DN, Heap GA, Hofmann S, Huizinga TW, Hunt S, Langford C, Lee J, Mansfield J, Marrosu MG, Mathew CG, Mein CA, Müller-Quernheim J, Nutland S, Onengut-Gumuscu S, Ouwehand W, Pearce K, PrescottNJ, Posthumus MD, Potter S, Rosati G, Sambrook J, Satsangi J, Schreiber S, Shtir C, Simmonds MJ, Sudman M, Thompson SD, Toes R, Trynka G, Vyse TJ, Walker NM, Weidinger S, Zhernakova A, Zoledziewska M; Type 1 Diabetes Genetics Consortium; UK Inflammatory Bowel Disease (IBD) Genetics Consortium; Wellcome Trust Case Control Consortium, Weersma RK, Gough SC, Sawcer S, Wijmenga C, Parkes M, Cucca F, Franke A, Deloukas P, Rich SS, Todd JA, van Heel DA. Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry. Nature Genetics 2011; 44:3-5

1458 Huth J, Buchholz M, Kraus JM, Molhave K, Gradinaru C, v. Wichert G, Gress TM, Neumann H, Kestler HA. TimeLapseAnalyzer: multi-target analysis for live-cell imaging and time-lapse microscopy. Comput Methods Programs Biomed. 2011 Nov;104(2):227-34. Epub 2011 Jun 25.

1457 IBC 50K CAD Consortium. Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 2011;7(9):e1002260.

1456 Imig J., Motsch N., Zhu J.Y., Barth S., Okoniewski M., Reineke T., Tinguely M., Faggioni A., Trivedi P., Meister G., Renner C. & Grässer F.A. microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma. Nucleic Acids Research, 39(5):1880-1893.

1455 Ingason A, Kirov G, Giegling I, Hansen T, Isles AR, Jakobsen KD, Kristinsson KT, le Roux L, Gustafsson O, Craddock N, Möller HJ, McQuillin A, Muglia P, Cichon S, Rietschel M, Ophoff RA, Djurovic S, Andreassen OA, Pietiläinen OP, Peltonen L, Dempster E, Collier DA, St Clair D, Rasmussen HB, Glenthøj BY, Kiemeney LA, Franke B, Tosato S, Bonetto C, Saemundsen E, Hreidarsson SJ; GROUP Investigators, Nöthen MM, Gurling H, O'Donovan MC, Owen MJ, Sigurdsson E, Petursson H, Stefansson H, Rujescu D, Stefansson K, Werge T. Maternally Derived Microduplications at 15q11-q13: Implication of Imprinted Genes in Psychotic Illness. Am J Psychiatry. 2011 Apr;168(4):408-17. Epub 2011 Feb 15.

1454 International Consortium for Blood Pressure Genome-Wide Association Studies, Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang SJ, Pihur V, Vollenweider P, O'Reilly PF, Amin N, Bragg-Gresham JL, Teumer A, Glazer NL, Launer L, Zhao JH, Aulchenko Y, Heath S, Sõber S, Parsa A, Luan J, Arora P, Dehghan A, Zhang F, Lucas G, Hicks AA, Jackson AU, Peden JF, Tanaka T, Wild SH, Rudan I, Igl W, Milaneschi Y, Parker AN, Fava C, Chambers JC, Fox ER, Kumari M, Go MJ, van der Harst P, Kao WH, Sjögren M, Vinay DG, Alexander M, Tabara Y, Shaw-Hawkins S, Whincup PH, Liu Y, Shi G, Kuusisto J, Tayo B, Seielstad M, Sim X, Nguyen KD, Lehtimäki T, Matullo G, Wu Y, Gaunt TR, Onland-Moret NC, Cooper MN, Platou CG, Org E, Hardy R, Dahgam S, Palmen J, Vitart V, Braund PS, Kuznetsova T, Uiterwaal CS, Adeyemo A, Palmas W, Campbell H, Ludwig B, Tomaszewski M, Tzoulaki I, Palmer ND; CARDIoGRAM consortium; CKDGen Consortium; KidneyGen Consortium; EchoGen consortium; CHARGE-HF consortium, Aspelund T, Garcia M, Chang YP, O'Connell JR, Steinle NI, Grobbee DE, Arking DE, Kardia SL, Morrison AC, Hernandez D, Najjar S, McArdle WL, Hadley D, Brown MJ, Connell JM, Hingorani AD, Day IN, Lawlor DA, Beilby JP, Lawrence RW, Clarke R, Hopewell JC, Ongen H, Dreisbach AW, Li Y, Young JH, Bis JC, Kähönen M, Viikari J, Adair LS, Lee NR, Chen MH, Olden M, Pattaro C, Bolton JA, Köttgen A, Bergmann S, Mooser V, Chaturvedi N, Frayling TM, Islam M, Jafar TH, Erdmann J, Kulkarni SR, Bornstein SR, Grässler J, Groop L, Voight BF, Kettunen J, Howard P, Taylor A, Guarrera S, Ricceri F, Emilsson V, Plump A, Barroso I, Khaw KT, Weder AB, Hunt SC, Sun YV, Bergman RN, Collins FS, Bonnycastle LL, Scott LJ, Stringham HM, Peltonen L, Perola M, Vartiainen E, Brand SM, Staessen JA, Wang TJ, Burton PR, Artigas MS, Dong Y, Snieder H, Wang X, Zhu H, Lohman KK, Rudock ME, Heckbert SR, Smith NL, Wiggins KL, Doumatey A, Shriner D, Veldre G, Viigimaa M, Kinra S, Prabhakaran D, Tripathy V, Langefeld CD, Rosengren A, Thelle DS, Corsi AM, Singleton A, Forrester T, Hilton G, McKenzie CA, Salako T, Iwai N, Kita Y, Ogihara T, Ohkubo T, Okamura T, Ueshima H, Umemura S, Eyheramendy S, Meitinger T, Wichmann HE, Cho YS, Kim HL, Lee JY, Scott J, Sehmi JS, Zhang W, Hedblad B, Nilsson P, Smith GD, Wong A, Narisu N, Stan?áková A, Raffel LJ, Yao J, Kathiresan S, O'Donnell CJ, Schwartz SM, Ikram MA, Longstreth WT Jr, Mosley TH, Seshadri S, Shrine NR, Wain LV, Morken MA, Swift AJ, Laitinen J, Prokopenko I, Zitting P, Cooper JA, Humphries SE, Danesh J, Rasheed A, Goel A, Hamsten A, Watkins H, Bakker SJ, van Gilst WH, Janipalli CS, Mani KR, Yajnik CS, Hofman A, Mattace-Raso FU, Oostra BA, Demirkan A, Isaacs A, Rivadeneira F, Lakatta EG, Orru M, Scuteri A, Ala-Korpela M, Kangas AJ, Lyytikäinen LP, Soininen P, Tukiainen T, Würtz P, Ong RT, Dörr M, Kroemer HK, Völker U, Völzke H, Galan P, Hercberg S, Lathrop M, Zelenika D, Deloukas P, Mangino M, Spector TD, Zhai G, Meschia JF, Nalls MA, Sharma P, Terzic J, Kumar MV, Denniff M, Zukowska-Szczechowska E, Wagenknecht LE, Fowkes FG, Charchar FJ, Schwarz PE, Hayward C, Guo X, Rotimi C, Bots ML, Brand E, Samani NJ, Polasek O, Talmud PJ, Nyberg F, Kuh D, Laan M, Hveem K, Palmer LJ, van der Schouw YT, Casas JP, Mohlke KL, Vineis P, Raitakari O, Ganesh SK, Wong TY, Tai ES, Cooper RS, Laakso M, Rao DC, Harris TB, Morris RW, Dominiczak AF, Kivimaki M, Marmot MG, Miki T, Saleheen D, Chandak GR, Coresh J, Navis G, Salomaa V, Han BG, Zhu X, Kooner JS, Melander O, Ridker PM, Bandinelli S, Gyllensten UB, Wright AF, Wilson JF, Ferrucci L, Farrall M, Tuomilehto J, Pramstaller PP, Elosua R, Soranzo N, Sijbrands EJ, Altshuler D, Loos RJ, Shuldiner AR, Gieger C, Meneton P, Uitterlinden AG, Wareham NJ, Gudnason V, Rotter JI, Rettig R, Uda M, Strachan DP, Witteman JC, Hartikainen AL, Beckmann JS, Boerwinkle E, Vasan RS, Boehnke M, Larson MG, Järvelin MR, Psaty BM, Abecasis GR, Chakravarti A, Elliott P, van Duijn CM, Newton-Cheh C, Levy D, Caulfield MJ, Johnson T. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature. 2011 Sep 11; 478(7367):103-9.

1453 International Multiple Sclerosis Genetics Consortium; Wellcome Trust CaseControl Consortium 2, Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476(7359):214-9

1452 Ishikawa K, Dürr A, Klopstock T, Müller S, De Toffol B, Vidailhet M, Vighetto A, Marelli C, Wichmann HE, Illig T, Niimi Y, Sato N, Amino T, Stevanin G, Brice A, Mizusawa H. Pentanucleotide repeats at the spinocerebellar ataxia type 31 (SCA31) locus in Caucasians. Neurology. 2011

1451 Ivics Z, Izsvák Z, Chapman KM, Hamra FK. Sleeping Beauty transposon mutagenesis of the rat genome in spermatogonial stem cells. Methods. 2011 Apr;53(4):356-65. Epub 2010 Dec 28.PMID:21193047

1450 Jacobs G, Hellmig S, Huse K, Titz A, Franke A, Kwiatkowski R, Ott S, Kosmahl M, Fischbach W, Lucius R, Klapper W, Fölsch UR, Hampe J, Schreiber S, Rosenstiel P. Polymorphisms in the 3'-untranslated region of the CDH1 gene are a risk factor for primary gastric diffuse large B-cell lymphoma. Haematologica. 2011 Jul;96(7):987-95. Epub 2011 Apr 1.

1449 Jacquemont S, Reymond A, Zufferey F, Harewood L, Walters RG, Kutalik Z, Martinet D, Shen Y, Valsesia A, Beckmann ND, Thorleifsson G, Belfiore M, Bouquillon S, Campion D, de Leeuw N, de Vries BB, Esko T, Fernandez BA, Fernández-Aranda F, Fernández-Real JM, Gratacòs M, Guilmatre A, Hoyer J, Jarvelin MR, Kooy RF, Kurg A, Le Caignec C, Männik K, Platt OS, Sanlaville D, Van Haelst MM, Villatoro Gomez S, Walha F, Wu BL, Yu Y, Aboura A, Addor MC, Alembik Y, Antonarakis SE, Arveiler B, Barth M, Bednarek N, Béna F, Bergmann S, Beri M, Bernardini L, Blaumeiser B, Bonneau D, Bottani A, Boute O, Brunner HG, Cailley D, Callier P, Chiesa J, Chrast J, Coin L, Coutton C, Cuisset JM, Cuvellier JC, David A, de Freminville B, Delobel B, Delrue MA, Demeer B, Descamps D, Didelot G, Dieterich K, Disciglio V, Doco-Fenzy M, Drunat S, Duban-Bedu B, Dubourg C, El-Sayed Moustafa JS, Elliott P, Faas BH, Faivre L, Faudet A, Fellmann F, Ferrarini A, Fisher R, Flori E, Forer L, Gaillard D, Gerard M, Gieger C, Gimelli S, Gimelli G, Grabe HJ, Guichet A, Guillin O, Hartikainen AL, Heron D, Hippolyte L, Holder M, Homuth G, Isidor B, Jaillard S, Jaros Z, Jiménez-Murcia S, Helas GJ, Jonveaux P, Kaksonen S, Keren B, Kloss-Brandstätter A, Knoers NV, Koolen DA, Kroisel PM, Kronenberg F, Labalme A, Landais E, Lapi E, Layet V, Legallic S, Leheup B, Leube B, Lewis S, Lucas J, MacDermot KD, Magnusson P, Marshall C, Mathieu-Dramard M, McCarthy MI, Meitinger T, Mencarelli MA, Merla G, Moerman A, Mooser V, Morice-Picard F, Mucciolo M, Nauck M, Ndiaye NC, Nordgren A, Pasquier L, Petit F, Pfundt R, Plessis G, Rajcan-Separovic E, Ramelli GP, Rauch A, Ravazzolo R, Reis A, Renieri A, Richart C, Ried JS, Rieubland C, Roberts W, Roetzer KM, Rooryck C, Rossi M, Saemundsen E, Satre V, Schurmann C, Sigurdsson E, Stavropoulos DJ, Stefansson H, Tengström C, Thorsteinsdóttir U, Tinahones FJ, Touraine R, Vallée L, van Binsbergen E, Van der Aa N, Vincent-Delorme C, Visvikis-Siest S, Vollenweider P, Völzke H, Vulto-van Silfhout AT, Waeber G, Wallgren-Pettersson C, Witwicki RM, Zwolinksi S, Andrieux J, Estivill X, Gusella JF, Gustafsson O, Metspalu A, Scherer SW, Stefansson K, Blakemore AI, Beckmann JS, Froguel P. Mirror extreme BMI phenotypes associated with gene dosage at the chromosome 16p11.2 locus. Nature. 2011 Aug 31;478(7367):97-102. doi: 10.1038/nature10406.

1448 Jakubcakova V, Flachskamm C, Deussing JM, Kimura M. Deficiency of corticotropin-releasing hormone type-2 receptor alters sleep responses to bacterial lipopolysaccharide in mice. Brain Behav Immun. 2011 Nov;25(8):1626-36. Epub 2011 Jun 17.

1447 Jankowski V, Tölle M, Santos RA, Günthner T, Krause E, Beyermann M, Welker P, Bader M, Pinheiro SV, Sampaio WO, Lautner R, Kretschmer A, van der Giet M, Zidek W, Jankowski J. Angioprotectin: an angiotensin II-like peptide causing vasodilatory effects. FASEB J. 2011 Sep;25(9):2987-95. Epub 2011 May 31.

1446 Janse M, Lamberts LE, Franke L, Raychaudhuri S, Ellinghaus E, Muri Boberg K, Melum E, Folseraas T, Schrumpf E, Bergquist A, Björnsson E, Fu J, Jan Westra H, Groen HJM, Fehrmann RSN, Smolonska J, van den Berg LH, Ophoff R a, Porte RJ, Weismüller TJ, Wedemeyer J, Schramm C, Sterneck M, Günther R, Braun F, Vermeire S, Henckaerts L, Wijmenga C, Ponsioen CY, Schreiber S, Karlsen TH, Franke A, Weersma RK, Bjornsson E, Weismuller TJ, Gunther R. Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9. Hepatology 2011 Jun;53(6):1977-1985

1445 Jarick I, Vogel CI, Scherag S, Schäfer H, Hebebrand J, Hinney A / Scherag A. Novel common copy number variation for early onset extreme obesity on chromosome  11q11 identified by a genome-wide analysis. Hum Mol Genet. 2011 Feb 15;20(4):840-52.

1444 Jensen LR, Chen W, Moser B, Lipkowitz B, Schroeder C, Musante L, Tzschach A, Kalscheuer VM, Meloni I, Raynaud M, van Esch H, Chelly J, de Brouwer AP, Hackett A, van der Haar S, Henn W, Gecz J, Riess O, Bonin M, Reinhardt R, Ropers HH, Kuss AW. Hybridisation-based resequencing of 17 X-linked intellectual disability genes in 135 patients reveals novel mutations in ATRX, SLC6A8 and PQBP1. Eur J Hum Genet. 2011 Jan 26. [Epub ahead of print]

1443 Jeub M, Emrich M, Pradier B, Taha O, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Huylebroeck D, Zimmer A, Beck H, Racz I. The transcription factor Smad-interacting protein 1 controls pain sensitivity via modulation of DRG neuron excitability. Pain. 152(10):2384-98. DOI:10.1016/j.pain.2011.07.006

1442 Jiao H, Arner P, Dickson SL, Vidal H, Mejhert N, Henegar C, Taube M, Hansson C, Hinney A, Galan P, Simon C, Silveira A, Benrick A, Jansson JO, Bouloumié A, Langin D, Laville M, Debard C, Axelsson T, Rydén M, Kere J, Dahlman-Wright K, Hamsten A, Clement K, Dahlman I. Genetic association and gene expression analysis identify FGFR1 as a new susceptibility gene for human obesity. J Clin Endocrinol Metab. 2011 Jun;96(6):E962-6. Epub 2011 Mar 23. PubMed PMID: 21430024.

1441 Jiao H, Arner P, Hoffstedt J, Brodin D, Dubern B, Czernichow S, van't Hooft F, Axelsson T, Pedersen O, Hansen T, Sørensen TI, Hebebrand J, Kere J, Dahlman-Wright K, Hamsten A, Clement K, Dahlman I. Genome wide association study identifies KCNMA1 contributing to human obesity. BMC Med Genomics. 2011 Jun 28;4:51. PubMed PMID: 21708048; PubMed Central PMCID: PMC3148553.

1440 Johannes M, Fröhlich H, Sültmann H, Beißbarth T. pathClass: An R-Package for Integration of Pathway Knowledge into Support Vector Machines for Biomarker DiscoveryBioinformatics. 2011, in press.

1439 Jourdan C, Kloiber S, Nieters A, Seiler H, Himmerich H, Kohli MA, Lucae S, Wolfram G, Gieger C, Wichmann HE, Linseisen J. Gene-PUFA interactions and obesity risk. BRITISH JOURNAL OF NUTRITION 2011

1438 Jung K, Becker B, Brunner B, Beißbarth T. Comparison of Global Tests for Functional Gene Sets in Two-Group Designs and Selection of Potentially Effect-causing Genes. BIOINFORMATICS ORIGINAL PAPER Vol. 27 no. 10 2011, pages 1377–1383. doi:10.1093/bioinformatics/btr152

1437 Jung S, Warner LN, Pitsch J, Becker AJ, Poolos NP. Rapid loss of dendritic HCN channel expression in hippocampal pyramidal neurons following status epilepticus. J Neurosci. 2011 Oct 5;31(40):14291-14295. PMID: 21976514 PMCID: PMC3208968

1436 Just S, Berger IM, Meder B, Backs J, Marquart S, Eva Patzel, Gerd-Jörg Rauch; Tübingen 2000 Screen Consortium; Hugo A. Katus; Wolfgang Rottbauer. Protein kinase D2 controls cardiac valve formation in zebrafish by regulating HDAC5 activity. Circulation 2011 (epub ahead of print).

1435 Just S, Meder B, Berger IM, Etard C, Trano N, Patzel E, Hassel D, Marquart S, Dahme T, Vogel B, Fishman MC, Katus HA, Strahle U, Rottbauer W. The myosin-interacting protein smyd1 is essential for sarcomere organization. Journal of Cell Science 2011;124:3127-3136

1434 Kääb S, Crawford DC, Sinner MF, Behr ER, Kannankeril PJ, Wilde AA, Bezzina CR, Schulze-Bahr E, Guicheney P, Bishopric NH, Myerburg RJ, Schott JJ, Pfeufer A, Beckmann BM, Martens E, Zhang T, Stallmeyer B, Zumhagen S, Denjoy I, Bardai A, Van Gelder IC, Jamshidi Y, Dalageorgou C, Marshall V, Jeffery S, Shakir S, Camm AJ, Steinbeck G, Perz S, Lichtner P, Meitinger T, Peters A, Wichmann HE, Ingram C, Bradford Y, Carter S, Norris K, Ritchie MD, George AL Jr, Roden DM. A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes. Circulation-Cardiovascular Genetics 2011

1433 Kähler AK, Djurovic S, Rimol LM, Brown AA, Athanasiu L, Jönsson EG, Hansen T, Gústafsson O, Hall H, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, Clair DS, Sigurdsson E, Petursson H, Rujescu D, Melle I, Werge T, Steen VM, Dale AM, Matthews RT, Agartz I, Andreassen OA. Candidate Gene Analysis of the Human Natural Killer-1 Carbohydrate Pathway and Perineuronal Nets in Schizophrenia: B3GAT2 Is Associated with Disease Risk and Cortical Surface Area. Biol Psychiatry. (2011) Jan 1;69(1):90-6. doi.org/10.1016/j.biopsych.2010.07.035

1432 Kahraman D, Scheffler M, Zander T, Nogova L, Lammertsma A, Boellaard R, Neumaier B, Ullrich R, Holstein A, Dietlein M, Wolf J, Kobe C. Quantitative Analysis of Response to Treatment with Erlotinib in Advanced Non?Small Cell Lung Cancer Using 18F-FDG and 39-Deoxy-39-18F-Fluorothymidine PET. Journal of Nuclear Medicine, published on November 7, 2011 as  doi:10.2967/jnumed.111.094458

1431 Kahrizi K, Hu CH, Garshasbi M, Abedini SS, Ghadami S, Kariminejad R, Ullmann R, Chen W, Ropers HH, Kuss AW, Najmabadi H, Tzschach A. Next generation sequencing in a family with autosomal recessive Kahrizi syndrome (OMIM 612713) reveals a homozygous frameshift mutation in SRD5A3. Eur J Hum Genet. 2011 Jan;19(1):115-7. Epub 2010 Aug 11.

1430 Kamburov A, Cavill R, Ebbels TMD, Herwig R, Keun HC. Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA. Bioinformatics, 2011 Oct; 27(20):2917-2918. doi: 10.1093/bioinformatics/btr499

1429 Kam-Thong T, Pütz B, Karbalai N, Müller-Myhsok B, Borgwardt K. Epistasisdetection on quantitative phenotypes by exhaustive enumeration using GPUs. Bioinformatics. 2011 Jul 1;27(13):i214-21. doi:  10.1093/bioinformatics/btr218

1428 Kaplan RC, Petersen AK, Chen MH, Teumer A, Glazer NL, Döring A, Lam CS, Friedrich N, Newman A, Müller M, Yang Q, Homuth G, Cappola A, Klopp N, Smith H, Ernst F, Psaty BM, Wichmann HE, Sawyer DB, Biffar R, Rotter JI, Gieger C, Sullivan LS, Völzke H, Rice K, Spyroglou A, Kroemer HK, Ida Chen YD, Manolopoulou J, Nauck M, Strickler HD, Goodarzi MO, Reincke M, Pollak MN, Bidlingmaier M, Vasan RS, Wallaschofski H.A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3. Hum Mol Genet. 2011

1427 Katsouri L, Parr C, Bogdanovic N, Willem M, Sastre M. PPAR? co-activator-1? (PGC-1?) reduces amyloid-? generation through a PPAR?-dependent mechanism. J Alzheimers Dis. 2011 Feb 25

1426 Keklikoglou I, Koerner C, Schmidt C, Zhang JD, Heckmann D, Shavinskaya A, Allgayer H, Guckel B, Fehm T, Schneeweiss A, Sahin O, Wiemann S, Tschulena U (2011). MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-kappaB and TGF-beta signaling pathways. Oncogene. 2011 Dec 12. doi: 10.1038/onc.2011.571. [Epub ahead of print]

1425 Keller A, Harz C, Matzas M, Meder B, Katus HA, Ludwig N, Fischer U, Meese E. Identification of novel SNPs in glioblastoma using targeted resequencing. PLoS One. 2011;6(6):e18158. Epub 2011 Jun 10.

1424 Keller, A., Leidinger, P., Bauer, A., ElSharawi, A., Haas, J., Backes, C., Wendschlag, A., Giese, N., Tjaden, C., Ott, K., Werner, J., Hackert, T., Ruprecht, K., Huwer, H., Huebers, J., Jacobs, G., Rosenstiel, P., Dommisch, H., Schäfer, A., Müller-Quernheim, J., Wullich, B., Keck, B., Graf, N., Reichrath, J., Vogel, B., Nebel, A., Jager, S.U., Staehler, P., Amarantos, I., Boisguerin, V., Staehler, C., Beier, M., Scheffler, M., Büchler, M.W., Wischhusen, J., Häusler, S.F.M., Dietl, J., Hofmann, S., Lenhof, H.P., Schreiber, S., Katus, H.A., Rottbauer, W., Meder, B., Hoheisel, J.D., Franke, A. & Meese, E. Toward the blood-borne miRNome of human diseases. Nature Methods. 2011 Sep 4;8(10):841-3. doi: 10.1038/nmeth.1682.

1423 Kerick M, Isau M, Timmermann B, Sültmann H, Herwig R, Krobitsch S, Schaefer G, Verdorfer I, Bartsch G, Klocker H, Lehrach H, Schweiger MR. Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics. 2011 Sep 29;4:68.

1422 Kestler HA, Lausser L, Lindner W, Palm G. On the fusion of threshold classifiers for categorization and dimensionality reduction. Computational Statistics. 2011; 26(2): 321 - 340.

1421 Kiefer F, Witt SH, Frank J, Richter A, Treutlein J, Lemenager T, Nöthen MM, Cichon S, Batra A, Berner M, Wodarz N, Zimmermann US, Spanagel R, Wiedemann K, Smolka MN, Heinz A, Rietschel M, Mann K.  *These authors contributed equally. Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate. Pharmacogenomics J. 2011 Oct;11(5):368-74. doi: 10.1038/tpj.2010.51.;

1420 Kielbasa SM, Wan R, Sato K, Horton P, Frith MC. Adaptive seeds tame genomic sequence comparison. Genome Res. 2011 Mar;21(3):487-93. Epub 2011 Jan 5.

1419 Kiess W, Sergejev E, Körner A, Hebebrand J. Is it possible to treat obesity in children and adolescents?]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2011 May;54(5):527-32. German. PubMed PMID: 21547642.

1418 Kilpeläinen TO, Qi L, Brage S, Sharp SJ, Sonestedt E, Demerath E, Ahmad T, Mora S, Kaakinen M, Sandholt CH, Holzapfel C, Autenrieth CS, Hyppönen E, Cauchi S, He M, Kutalik Z, Kumari M, Stan?áková A, Meidtner K, Balkau B, Tan JT, Mangino M, Timpson NJ, Song Y, Zillikens MC, Jablonski KA, Garcia ME, Johansson S, Bragg-Gresham JL, Wu Y, van Vliet-Ostaptchouk JV, Onland-Moret NC, Zimmermann E, Rivera NV, Tanaka T, Stringham HM, Silbernagel G, Kanoni S, Feitosa MF, Snitker S, Ruiz JR, Metter J, Larrad MT, Atalay M, Hakanen M, Amin N, Cavalcanti-Proença C, Grøntved A, Hallmans G, Jansson JO, Kuusisto J, Kähönen M, Lutsey PL, Nolan JJ, Palla L, Pedersen O, Pérusse L, Renström F, Scott RA, Shungin D, Sovio U, Tammelin TH, Rönnemaa T, Lakka TA, Uusitupa M, Rios MS, Ferrucci L, Bouchard C, Meirhaeghe A, Fu M, Walker M, Borecki IB, Dedoussis GV, Fritsche A, Ohlsson C, Boehnke M, Bandinelli S, van Duijn CM, Ebrahim S, Lawlor DA, Gudnason V, Harris TB, Sørensen TI, Mohlke KL, Hofman A, Uitterlinden AG, Tuomilehto J, Lehtimäki T, Raitakari O, Isomaa B, Njølstad PR, Florez JC, Liu S, Ness A, Spector TD, Tai ES, Froguel P, Boeing H, Laakso M, Marmot M, Bergmann S, Power C, Khaw KT, Chasman D, Ridker P, Hansen T, Monda KL, Illig T, Järvelin MR, Wareham NJ, Hu FB, Groop LC, Orho-Melander M, Ekelund U, Franks PW, Loos RJ. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med. 2011 Nov;8(11):e1001116. Epub 2011 Nov 1.

1417 Kilpeläinen TO, Zillikens MC, Stan?ákova A, Finucane FM, Ried JS, Langenberg C, Zhang W, Beckmann JS, Luan J, Vandenput L, Styrkarsdottir U, Zhou Y, Smith AV, Zhao JH, Amin N, Vedantam S, Shin SY, Haritunians T, Fu M, Feitosa MF, Kumari M, Halldorsson BV, Tikkanen E, Mangino M, Hayward C, Song C, Arnold AM, Aulchenko YS, Oostra BA, Campbell H, Cupples LA, Davis KE, Döring A, Eiriksdottir G, Estrada K, Fernández-Real JM, Garcia M, Gieger C, Glazer NL, Guiducci C, Hofman A, Humphries SE, Isomaa B, Jacobs LC, Jula A, Karasik D, Karlsson MK, Khaw KT, Kim LJ, Kivimäki M, Klopp N, Kühnel B, Kuusisto J, Liu Y, Ljunggren O, Lorentzon M, Luben RN, McKnight B, Mellström D, Mitchell BD, Mooser V, Moreno JM, Männistö S, O'Connell JR, Pascoe L, Peltonen L, Peral B, Perola M, Psaty BM, Salomaa V, Savage DB, Semple RK, Skaric-Juric T, Sigurdsson G, Song KS, Spector TD, Syvänen AC, Talmud PJ, Thorleifsson G, Thorsteinsdottir U, Uitterlinden AG, van Duijn CM, Vidal-Puig A, Wild SH, Wright AF, Clegg DJ, Schadt E, Wilson JF, Rudan I, Ripatti S, Borecki IB, Shuldiner AR, Ingelsson E, Jansson JO, Kaplan RC, Gudnason V, Harris TB, Groop L, Kiel DP, Rivadeneira F, Walker M, Barroso I, Vollenweider P, Waeber G, Chambers JC, Kooner JS, Soranzo N, Hirschhorn JN, Stefansson K, Wichmann HE, Ohlsson C, O'Rahilly S, Wareham NJ, Speliotes EK, Fox CS, Laakso M, Loos RJ. Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet 2011

1416 Kleinhammer A, Wurst W, Kühn R. Constitutive and conditional RNAi transgenesis in mice. Methods. 2011 Apr;53(4):430-6. Epub 2010 Dec 22.

1415 Klengel T, Heck A, Pfister H, Brückl T, Hennings JM, Menke A, Czamara D,Müller-Myhsok B, Ising M. Somatization in major depression--clinical features and genetic associations. Acta Psychiatr Scand. 2011 Oct;124(4):317-28. doi:10.1111/j.1600-0447.2011.01743.x

1414 Klostermeier UC et al. (2011). A tissue-specific landscape of sense/antisense transcription in the mouse intestine. BMC Genomics 12:305

1413 Knöll R, Buyandelger B, Lab M. The sarcomeric Z-disc and Z-discopathies. J Biomed Biotechnol. 2011; 2011:569628.

1412 Knöll R, Linke WA, Zou P, Miocic S, Kostin S, Buyandelger B, Ku CH, Neef S, Bug M, Schäfer K, Knöll G, Felkin LE, Wessels J, Toischer K, Hagn F, Kessler H, Didié M, Quentin T, Maier LS, Teucher N, Unsöld B, Schmidt A, Birks EJ, Gunkel S, Lang P, Granzier H, Zimmermann WH, Field LJ, Faulkner G, Dobbelstein M, Barton PJ, Sattler M, Wilmanns M, Chien KR. Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart. Circ Res. 2011; 109:758-69.

1411 Knoll S, Bulik CM, Hebebrand J. Do the currently proposed DSM-5 criteria for anorexia nervosa adequately consider developmental aspects in children and adolescents? Eur Child Adolesc Psychiatry. 2011 Feb;20(2):95-101. Epub 2010 Nov 25. PubMed PMID: 21107872.

1410 Köberle, S.C., J. Romir, S. Fischer, A. Köberle, V. Schattel, W. Albrecht, C. Grütter, O. Werz, D. Rauh, T. Stehle, S.A. Laufer. Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. Nat Chem Biol, 2011, 8(2):141-43.

1409 Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Müller-Myhsok B, Binder EB. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 2011 Apr 28;70(2):252-65.

1408 König IR, Schumacher J, Hoffmann P, Kleensang A, Ludwig KU, Grimm T, Neuhoff N, Preis M, Roeske D, Warnke A, Propping P, Remschmidt H, Nöthen MM, Ziegler A, Müller-Myhsok B, Schulte-Körne G. Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21. Am J Med Genet B Neuropsychiatr Genet. 2011 Jan;156(1):36-43. doi: 10.1002/ajmg.b.31135

1407 Konstandin N, Bultmann S, Szwagierczak A, Dufour A, Ksienzyk B, Schneider F, Herold T, Mulaw M, Kakadia PM, Schneider S, Spiekermann K, Leonhardt H, Bohlander SK. Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia. Leukemia. 2011;25:1649-1652.

1406 Korshunov A, Remke M, Kool M, Hielscher T, Northcott PA, Williamson D, Pfaff E, Witt H, Jones DT, Ryzhova M, Cho YJ, Wittmann A, Benner A, Weiss WA, von Deimling A, Scheurlen W, Kulozik AE, Clifford SC, Peter Collins V, Westermann F, Taylor MD, Lichter P, Pfister SM. Biological and clinical heterogeneity of MYCN-amplified medulloblastoma. Acta Neuropathol. 2012 Apr;123(4):515-27. Epub 2011 Dec 9.

1405 Kortüm F, Das S, Flindt M, Morris-Rosendahl DJ, Stefanova I, Goldstein A, Horn D, Klopocki E, Kluger G, Martin P, Rauch A, Roumer A, Saitta S, Walsh LE, Wieczorek D, Uyanik G, Kutsche K, Dobyns WB. The core FOXG1 syndrome phenotype consists of postnatal microcephaly, severe mental retardation, absent language, dyskinesia, and corpus callosum hypogenesis.J Med Genet. 2011 Mar 25. [Epub ahead of print]

1404 Kraft M, Cirstea IC, Voss AK, Thomas T, Goehring I, Sheikh BN, Gordon L, Scott H, Smyth GK, Ahmadian MR, Trautmann U, Zenker M, Tartaglia M, Ekici A, Reis A, Dörr HG, Rauch A, Thiel CT. Disruption of the histone acetyltransferase MYST4 leads to a Noonan syndrome-like phenotype and hyperactivated MAPK signaling in humans and mice. J Clin Invest 121:3479-3491. PMID:21804188

1403 Krallinger, M., M. Vazquez, F. Leitner, D. Salgado, A. Chatr-aryamontri, A. Winter, L. Perfetto, L. Briganti, L. Licata, M. Iannuccelli, L. Castagnoli, G. Cesareni, M. Tyers, G. Schneider, F. Rinaldi, R. Leaman, G. Gonzalez, S. Matos, S. Kim, W.J. Wilbur, L. Rocha, H. Shatkay, A.V. Tendulkar, S. Agarwal, F. Liu, X. Wang, R. Rak, K. Noto, C. Elkan, Z. Lu, R.I. Dogan, J.F. Fontaine, M.A. Andrade-Navarro and A. Valencia. 2011. The Protein-Protein Interaction tasks of BioCreative III: classification/ranking of articles and linking bio-ontology concepts to full text. BMC Bioinformatics. 12 Suppl 8:S3.

1402 Kramer JM, Kochinke K, Oortveld MAW, Marks H, Kramer D, de Jong EK, Asztalos Z, Westwood JT, Stunnenberg HG, Sokolowski MB, Keleman K, van Bokhoven, H. and Schenck, A. Epigenetic regulation of learning & memory by Drosophila EHMT/G9a. PLoS Biol. 2011, 9(1): e1000569PMID: 21245904

1401 Kranz AL, Eils R, König R. Enhancers regulate progression of development in mammalian cells. Nucleic Acids Res., 39, 8689-702.

1400 Krastev DB, Buchholz F. Ribosome biogenesis and p53: Who is regulating whom? Cell Cycle. Oct 15;10(20):3417-8

1399 Krastev, Dragomir B.  Mikolaj Slabicki, Maciej Paszkowski-Rogacz, Nina C. Hubner, Magno Junqueira, Andrej Shevchenko, Matthias Mann, Karla M. Neugebauer and Frank Buchholz. A systematic RNAi synthetic interaction screen reveals a link between p53 and snoRNP assembly. Nature Cell Biology 13, 809?818 (2011). doi:10.1038/ncb2264

1398 Kraus JM, Müssel C, Palm G, Kestler HA. Multi-objective selection for collecting cluster alternatives. Computational Statistics. 2011; 26(2): 341- 354.

1397 Krueppel R, Remy S, Beck H. Dendritic integration in hippocampal dentate granule cells. Neuron. 2011 Aug 11;71(3):512-28. PMID: 21835347

1396 Krüger R, Sharma M, Riess O, Gasser T, van Broeckhoven C, Theuns J, Aasly J, Annesi G, Bentivoglio AR, Brice A, Elbaz A, Farrer M, Ferrarese C, Ferraris A, Hadjigeorgiou GM, Hattori N, Klein C, Lin JJ, Mellick GD, Opala G, Prigione A, Tan EK, Toda T, Valente EM, Wirdefeldt K, Wszolek Z, Maraganore DM for the Genetic Epidemiology of Parkinson disease  consortium. (2011) A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease. Neurobiol Aging 32:548.e9-548.e18

1395 Krumova P, Meulmeester E, Garrido M, Tirard M, Hsiao HH, Bossis G, Urlaub H, Zweckstetter M, Kügler S, Melchior F, Bähr M, Weishaupt JH. Sumoylation inhibits alpha-synuclein aggregation and toxicity. J Cell Biol. 2011 Jul 11;194(1):49-60.

1394 Krupp M, Maass T, Marquardt JU, Staib F, Bauer T, König R, Biesterfeld S, Galle PR, Tresch A, Teufel A. The functional cancer map: a systems-level synopsis of genetic deregulation in cancer. BMC Med Genomics. 2011 Jun 30;4:53.

1393 Küchler J, Hartmann W, Waha A, Koch A, Endl E, Wurst P, Kindler D, Mikeska T, Waha A, Goodyer CG, Büttner R, Schilling K, Pietsch T. p75(NTR) induces apoptosis in medulloblastoma cells. Int J Cancer. 2011 Apr 15;128(8):1804-12. doi: 10.1002/ijc.25508.

1392 Kuechler A, Buysse K, Clayton-Smith J, Le Caignec C, David A, Engels H, Kohlhase J, Mari F, Mortier G, Renieri A, Wieczorek D (2011). Five patients with novel overlapping interstitial deletions in 8q22.2q22.3. Am J Med Genet A. 155A(8):1857-64

1391 Küffner, R., T. Petri, P. Tavakkolkhah, L. Windhager, R. Zimmer. Inferring Gene Regulatory Networks by ANOVA. Bioinformatics. 2012 May 15;28(10):1376-82. Epub 2012 Mar 30.

1390 Kunde SA, Musante L, Grimme A, Fischer U, Müller E, Wanker EE, Kalscheuer VM. The X-chromosome-linked intellectual disability protein PQBP1 is a component of neuronal RNA granules and regulates the appearance of stress granules. Hum Mol Genet. 2011 Dec 15;20(24):4916-31. Epub 2011 Sep 20.

1389 Kurz A, Rabbani N, Walter M, Bonin M, Thornalley P, Auburger G, Gispert S. Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress. Cell Mol Life Sci. 2011 Feb;68(4):721-33.

1388 Kuss AW, Garshasbi M, Kahrizi K, Tzschach A, Behjati F, Darvish H, Abbasi-Moheb L, Puettmann L, Zecha A, Weissmann R, Hu H, Mohseni M, Abedini SS, Rajab A, Hertzberg C, Wieczorek D, Ullmann R, Ghasemi-Firouzabadi S, Banihashemi S, Arzhangi S, Hadavi V, Bahrami-Monajemi G, Kasiri M, Falah M, Nikuei P, Dehghan A, Sobhani M, Jamali P, Ropers HH, Najmabadi H. Autosomal recessive mental retardation: homozygosity mapping identifies 27 single linkage intervals, at least 14 novel loci and several mutation hotspots. Hum Genet. 2011 Feb;129(2):141-8. Epub 2010 Nov 10.

1387 Lamberto GR, Torres-Monserrat V, Bertoncini CW, Salvatella X, Zweckstetter M, Griesinger C, Fernández CO. Toward the discovery of effective polycyclic inhibitors of alpha-synuclein amyloid assembly. J Biol Chem. 2011 Sep 16;286(37):32036-44. Epub 2011 Jul 27.

1386 Lammel S, Ion DI, Roeper J, Malenka RC. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli.Neuron. 2011 Jun 9;70(5):855-62

1385 Lanktree MB, Guo Y, Murtaza M, Glessner JT, Bailey SD, Onland-Moret NC, Lettre G, Ongen H, Rajagopalan R, Johnson T, Shen H, Nelson CP, Klopp N, Baumert J, Padmanabhan S, Pankratz N, Pankow JS, Shah S, Taylor K, Barnard J, Peters BJ, Maloney CM, Lobmeyer MT, Stanton A, Zafarmand MH, Romaine SP, Mehta A, van Iperen EP, Gong Y, Price TS, Smith EN, Kim CE, Li YR, Asselbergs FW, Atwood LD, Bailey KM, Bhatt D, Bauer F, Behr ER, Bhangale T, Boer JM, Boehm BO, Bradfield JP, Brown M, Braund PS, Burton PR, Carty C, Chandrupatla HR, Chen W, Connell J, Dalgeorgou C, Boer A, Drenos F, Elbers CC, Fang JC, Fox CS, Frackelton EC, Fuchs B, Furlong CE, Gibson Q, Gieger C, Goel A, Grobbee DE, Hastie C, Howard PJ, Huang GH, Johnson WC, Li Q, Kleber ME, Klein BE, Klein R, Kooperberg C, Ky B, Lacroix A, Lanken P, Lathrop M, Li M, Marshall V, Melander O, Mentch FD, Meyer NJ, Monda KL, Montpetit A, Murugesan G, Nakayama K, Nondahl D, Onipinla A, Rafelt S, Newhouse SJ, Otieno FG, Patel SR, Putt ME, Rodriguez S, Safa RN, Sawyer DB, Schreiner PJ, Simpson C, Sivapalaratnam S, Srinivasan SR, Suver C, Swergold G, Sweitzer NK, Thomas KA, Thorand B, Timpson NJ, Tischfield S, Tobin M, Tomaszweski M, Verschuren WM, Wallace C, Winkelmann B, Zhang H, Zheng D, Zhang L, Zmuda JM, Clarke R, Balmforth AJ, Danesh J, Day IN, Schork NJ, de Bakker PI, Delles C, Duggan D, Hingorani AD, Hirschhorn JN, Hofker MH, Humphries SE, Kivimaki M, Lawlor DA, Kottke-Marchant K, Mega JL, Mitchell BD, Morrow DA, Palmen J, Redline S, Shields DC, Shuldiner AR, Sleiman PM, Smith GD, Farrall M, Jamshidi Y, Christiani DC, Casas JP, Hall AS, Doevendans PA, Christie JD, Berenson GS, Murray SS, Illig T, Dorn GW 2nd, Cappola TP, Boerwinkle E, Sever P, Rader DJ, Reilly MP, Caulfield M, Talmud PJ, Topol E, Engert JC, Wang K, Dominiczak A, Hamsten A, Curtis SP, Silverstein RL, Lange LA, Sabatine MS, Trip M, Saleheen D, Peden JF, Cruickshanks KJ, März W, O'Connell JR, Klungel OH, Wijmenga C, Maitland-van der Zee AH, Schadt EE, Johnson JA, Jarvik GP, Papanicolaou GJ; Hugh Watkins on behalf of PROCARDIS, Grant SF, Munroe PB, North KE, Samani NJ, Koenig W, Gaunt TR, Anand SS, van der Schouw YT; Meena Kumari on behalf of the Whitehall II Study and the WHII 50K Group, Soranzo N, Fitzgerald GA, Reiner A, Hegele RA, Hakonarson H, Keating BJ. Metaanalysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet 2011 ;88:6-18.

1384 Lebedeva E, Stingl JC, Thal DR, Ghebremedhin E, Strauss J, Ozer E, Bertram L, Einem BV, Tumani H, Otto M, Riepe MW, Högel J, Ludolph AC, Arnim CA. Genetic variants in PSEN2 and correlation to CSF ?-amyloid42 levels in AD. Neurobiol Aging Sept 17 [Epub ahead of print; PMID: 20850903].

1383 Lemke D, Pfenning PN, Sahm F, Klein AC, Kempf T, Warnken U, Schnölzer M, Tudoran R, Weller M, Platten M, Wick W. Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness. Clin Cancer Res. 2012 Jan 1;18(1):105-17. Epub 2011 Nov 11

1382 Lennertz L, Quednow BB, Benninghoff J, Wagner M, Maier W, Mössner R. Impact of TCF4 on the genetics of schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2011 Nov;261 Suppl 2:S161-5

1381 Lennertz L, Quednow BB, Schuhmacher A, Petrovsky N, Frommann I, Schulze-Rauschenbach S, Landsberg MW, Steinbrecher A, Höfels S, Pukrop R, Klosterkötter J, Franke PE, Wölwer W, Gaebel W, Häfner H, Maier W, Wagner M, Mössner R. The functional coding variant Asn107Ile of the neuropeptide S receptor gene (NPSR1) is associated with schizophrenia and modulates verbal memory and the acoustic startle response. Int J Neuropsychopharmacol. 2011 Nov 14:1-11. [Epub ahead of print] (im Druck)PMID: 22078257

1380 Lennertz L, Rujescu D, Wagner M, Frommann I, Schulze-Rauschenbach S, Schuhmacher A, Landsberg MW, Franke P, Möller HJ, Wölwer W, Gaebel W, Häfner H, Maier W, Mössner R. Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients. Neuropsychobiology. 2011;63(3):131-6.

1379 Lepage P, Häsler R, Spehlmann ME, Rehman A, Zvirbliene A, Begun A, Ott S, Kupcinskas L, Doré J, Raedler A, Schreiber S. Twin study indicates loss of interaction between microbiota and mucosa of patients with ulcerative colitis. Gastroenterology. 2011 Jul;141(1):227-36. Epub 2011 Apr 16

1378 Lerche H, Vezzani A, Beck H, Blümcke I, Weber Y, Elger C. Neue Entwicklungen der Epileptogenese und therapeutische Perspektiven. Nervenarzt 2011;82:978-85.

1377 Leushacke M, Spörle R, Bernemann C, Brouwer-Lehmitz A, Fritzmann J, Theis M, Buchholz F, Herrmann BG, Morkel M. An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression. PLoS One. 2011;6(8):e23381.

1376 Ley S, Ley-Zaporozhan J, Günther P, Deubzer HE, Witt O, Schenk JP. Neuroblastoma imaging. Rofo. 2011 Mar;183(3):217-25. Epub 2010 Dec 17

1375 Lidia Becla, Jeantine E. Lunshof, David Gurwitz, Tobias Schulte in den Bäumena, Hans V. Westerhoff, Bodo M. H. Lange and Angela Brand. Health technology assessment in the era of personalized health care. International Journal of Technology Assessment in Health Care (2011), 27: 118-126

1374 Lill CM, Bertram L. Towards unveiling the genetics of neurodegenerative diseases. Semin Neurol. 2011 Nov;31(5):531-41.

1373 Lin Z, Hegarty JP, Cappel JA, Yu W, Chen X, Faber P, Wang Y, Kelly AA, Poritz LS, Peterson BZ, Schreiber S, Fan JB, Koltun WA. Identification of disease-associated DNA methylation in intestinal tissues from patients with inflammatory bowel disease. Clin Genet. 2011 Jul;80(1):59-67. doi: 10.1111/j.1399-0004.2010.01546.x. Epub 2010 Oct 18

1372 Lionel AC et al. (2011). Rare copy number variation discovery and cross-disorder comparisons identify risk genes for ADHD. Sci Transl Med 2011;3(95):95ra75.

1371 Liu J, Rädler D, Illi S, Klucker E, Turan E, von Mutius E, Kabesch M, Schaub B. TLR2 polymorphisms influence neonatal regulatory T cells depending on maternal atopy. Allergy. 2011 Mar 4. doi: 10.1111/j.1398-9995.2011.02573.x.

1370 Lluis A, Schedel M, Liu J, Illi S, Depner M, von Mutius E, Kabesch M, Schaub B. Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMAgene expression and IL-17 secretion. J Allergy Clin Immunol. 2011Jun;127(6):1587-94.e6. Epub 2011 May 4. PubMed PMID: 21546069.

1369 Löffler H, Fechter A, Matuszewska M, Saffrich R, Mistrik M, Marhold J, HornungC, Westermann F, Bartek J, Krämer A. Cep63 Recruits Cdk1 to the Centrosome:Implications for Regulation of Mitotic Entry, Centrosome Amplification, andGenome Maintenance. Cancer Res. 2011 Mar 15;71(6):2129-2139.

1368 London, W.B., V. Castel, T. Monclair, P.F. Ambros, A.D. Pearson, S.L. Cohn, F. Berthold, A. Nakagawara, R.L. Ladenstein, T. Iehara, and K.K. Matthay. Clinical and biologic features predictive of survival after relapse of neuroblastoma: a report from the International Neuroblastoma Risk Group project. J Clin Oncol, 2011. 29(24): p. 3286-92.

1367 Lopes, T.J., M. Schaefer, J. Schoemaker, Y. Matsuoka, J.F. Fontaine, G. Neumann, M.A. Andrade-Navarro, Y. Kawaoka and H. Kitano. 2011. Tissue-specific subnetworks and characteristics of publicly available human protein interaction databases. Bioinformatics. 27:2414-2421.

1366 Lückerath K, Kirkin V, Melzer IM, Thalheimer FB, Siele D, Milani W, Adler T, Aguilar-Pimentel A, Horsch M, Michel G, Beckers J, Busch DH, Ollert M, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Staal FJ, Rajalingam K, Hueber AO, Strobl LJ, Zimber-Strobl U, Zörnig M. Immune modulation by Fas ligand reverse signaling: lymphocyte proliferation is attenuated by the intracellular Fas ligand domain. Blood. 13;117(2):519-29.

1365 Luotola K, Pietilä A, Zeller T, Moilanen L, Kähönen M, Nieminen MS, Kesäniemi YA, Blankenberg S, Jula A, Perola M, Salomaa V; Health 2000 and FINRISK97 Studies. Associations between interleukin-1 (IL-1) gene variations or IL-1 receptor antagonist levels and the development of type 2 diabetes. J Intern Med. 2011 Mar;269(3):322-32.

1364 Lutsik P, Feuerbach L, Arand J, Lengauer T, Walter J, Bock C. BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing. Nucleic Acids Res. 2011, Epub May 11.

1363 Madisch A, Hellmig S, Schreiber S, Bethke B, Stolte M, Miehlke S. Allelic variation of the matrix metalloproteinase-9 gene is associated with collagenous colitis. Inflamm Bowel Dis. 2011 Nov;17(11):2295-8. doi: 10.1002/ibd.21640. Epub 2011 Feb 8

1362 Maetzler W, Schmid SP, Wurster I, Liepelt I, Gaenslen A, Gasser T, Berg D. Reduced but not oxidized cerebrospinal fluid glutathione levels are lowered in Lewy body diseases. Mov Disord. 2011 Jan;26(1):176-8.

1361 Malhotra D, McCarthy S, Michaelson JJ, Vacic V, Burdick KE, Yoon S, Cichon S, Corvin A, Gary S, Gershon ES, Gill M, Karayiorgou M, Kelsoe JR, Krastoshevsky O, Krause V, Leibenluft E, Levy DL, Makarov V, Bhandari A, Malhotra AK, McMahon FJ, Nöthen MM, Potash JB, Rietschel M, Schulze TG, Sebat J. High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron. 2011 Dec 22;72(6):951-63.

1360 Maljevic S, Naros G, Yalçin Ö, Blazevic D, Loeffler H, Ca?layan H, Steinlein OK, Lerche H. Temperature and pharmacological rescue of a folding-defective, dominant-negative KV7.2 mutation associated with neonatal seizures. Hum Mutat. 2011;32:E2283-93.

1359 Malterer G, Dölken L, Haas J. The miRNA-targetome of KSHV and EBV in human B-cells. RNA Biol. 2011 Jan 1;8(1). [Epub ahead of print]

1358 Marenholz I, Bauerfeind A, Esparza-Gordillo J, Kerscher T, Granell R, Nickel R, Lau S, Henderson J, Lee YA. The eczema risk variant on chromosome 11q13 (rs7927894) in the population-based ALSPAC cohort: a novel susceptibility factor for asthma and hay fever. Hum Mol Genet 20, 2443-2449. 2011.

1357 Marenholz I, Gimenez Rivera VA, Esparza-Gordillo J, Bauerfeind A, Lee-Kirsch MA, Ciechanowicz A, Kurek M, Piskackova T, Macek M, Lee YA. Association screening in the epidermal differentiation complex (EDC) identifies an SPRR3 repeat number variant as a risk factor for eczema. J Invest Dermatol 131, 1644-1649. 2011.

1356 Marschalek R. Mechanisms of leukemogenesis by MLL fusion proteins. Br J Haematol 152, 141-154. (2011).

1355 Maucher M, Kracher B, Kühl M, Kestler HA. Inferring Boolean network structure via correlation. Bioinformatics. 2011; 27(11): 1529-36.

1354 Maucher M, Schöning U, Kestler HA. Search heuristics and the influence of non-perfect randomness: examining Genetic Algorithms and Simulated Annealing. Computational Statistics. 2011; 26(2): 303 - 320.

1353 Mazur PK, Siveke JT. Genetically engineered mouse models of pancreatic cancer: unravelling tumour biology and progressing translational oncology. Gut. 2011 Aug 26. [Epub ahead of print]

1352 McMahon FJ, Akula N, Cichon S, Detera-Wadleigh SD, Edenberg H, Holsboer F, Nöthen MM, Nurnberger JI, Potash J, Preisig M, Rietschel M, Schulze TG. Replication of association of 3p21.1 with susceptibility to bipolar disorder but not major depression. Nat Genet. 2011 Jan;43(1):3-5

1351 Mead S, Uphill J, Beck J, Poulter M, Campbell T, Lowe J, Adamson G, Hummerich H, Klopp N, Rückert IM, Wichmann HE, Azazi D, Plagnol V, Pako WH, Whitfield J, Alpers MP, Whittaker J, Balding DJ, Zerr I, Kretzschmar H, Collinge J. Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP. Hum Mol Genet. 2011

1350 Medenbach Jan,  Markus Seiler and Matthias W. Hentze. Translational control via protein-regulated upstream open reading frames. Cell. 2011 Jun 10;145(6):902-13

1349 Meder B, Bergmann CE, Keller A, Just S, Katus HA, Hoefer IE, Buschmann IR. Quantification of Collateral Artery Growth by Automated Fluorescent Microsphere Perfusion. Int J Cardiol. 2011 May 20. [Epub ahead of print]

1348 Meder B, Haas J, Keller A, Heid C, Just S, Borries A, Boisguerin V, Scharfenberger-Schmeer M, Stähler P, Beier M, Weichenhan D, Strom T, Pfeufer A, Korn B, Katus HA, Rottbauer W. Targeted Next-Generation Sequencing for the Molecular Genetic Diagnostics of Cardiomyopathies. Circulation Cardiovascular Genetics 2011 (epub ahead of print)

1347 Meder B, Huttner IG, Sedaghat-Hamedani F, Just S, Dahme T, Frese KS, Vogel B, Köhler D, Kloos W, Rudloff J, Marquart S, Katus HA, Rottbauer W. PINCH proteins regulate cardiac contractility by modulating ILK-PKB signaling. Mol Cell Biol. 2011 Aug;31(16):3424-35. Epub 2011 Jun 13.

1346 Meder B, Keller A, Vogel B, Haas J, Sedaghat-Hamedani F, Kayvanpour E, Just S, Borries A, Rudloff J, Leidinger P, Meese E, Katus HA, Rottbauer W. Microrna signatures in total peripheral blood as novel biomarkers for acute myocardial infarction. Basic Res Cardiol. 106:13-23 (2011)

1345 Meder B, Scholz EP, Hassel D, Wolff C, Just S, Berger IM, Patzel E, Karle C, Katus HA, Rottbauer W. Reconstitution of Defective Protein Trafficking Rescues Long-QT Syndrome in Zebrafish. Biochem Biophys Res Commun. 2011 May 6;408(2):218-24. Epub 2011 Mar 31.

1344 Mehta D, Gonik M, Klengel T, Rex-Haffner M, Menke A, Rubel J, Mercer KB, Pütz B, Bradley B, Holsboer F, Ressler KJ, Müller-Myhsok B, Binder EB. Using polymorphisms in FKBP5 to define biologically distinct subtypes of posttraumatic stress disorder: evidence from endocrine and gene expression studies. Arch Gen Psychiatry. 2011 Sep;68(9):901-10. doi:10.1001/archgenpsychiatry.2011.50

1343 Meister G. Vision: Dicer leaps into view. Nature, 471(7338):308-9.

1342 Meixner, A, Boldt, K, Van Troys, M, Askenazi, M, Gloeckner, CJ, Bauer, M, Marto, JA, Ampe, C, Kinkl, N, and Ueffing, M: A QUICK screen for Lrrk2 interaction partners--leucine-rich repeat kinase 2 is involved in actin cytoskeleton dynamics. Mol. Cell. Proteomics 2011 Jan. 1;10 (1), M110 001172. doi: 10.1074/mcp.M110.001172

1341 Melum E et al. (2011). Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci. Nat Genet 43(1):17-9

1340 Meyer LH, Eckhoff SM, Queudeville M, Kraus JM, Giordan M, Stursberg J, Zangrando A, Vendramini E, Möricke A, Zimmermann M, Schrauder A, Lahr G, Holzmann K, Schrappe M, Basso G, Stahnke K, Kestler HA, Te Kronnie G., Debatin KM. Early relapse in all is identified by time to leukemia in NOD/SCID mice and is characterized by a gene signature involving survival pathways. Cancer Cell. 2011; 19(2): 206-17.

1339 Miller C, Schwalb B, Maier K, Schulz D, Dümcke S, Zacher B, Mayer A, Sydow J, Marcinowski L, Dölken L*, Martin DE, Tresch A*, Cramer P*.* = joined corresponding authors. Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast. Mol Syst Biol. 2011 Jan 4;7:458.

1338 Minner S, Enodien M, Sirma H, Luebke AM, Krohn A, Mayer PS, Simon R, Tennstedt P, Müller J, Scholz L, Brase JC, Liu AY, Schlüter H, Pantel K, Schumacher U, Bokemeyer C, Steuber T, Graefen M, Sauter G, Schlomm T. ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy. Clin Cancer Res. 2011 Sep 15;17(18):5878-88

1337 Mirhashemi F, Scherneck S, Kluth O, Kaiser D, Vogel H, Kluge R, Schürmann A, Neschen S, Joost HG. Diet Dependence of Diabetes in the New Zealand Obese (NZO) Mouse: Total Fat, But not Fat Quality or Sucrose Accelerates and Aggravates Diabetes. Exp Clin Endocrinol Diabetes. 119:167-171 (2011).

1336 Mittelstrass K, Ried JS, Yu Z, Krumsiek J, Gieger C, Prehn C, Roemisch-Margl W, Polonikov A, Peters A, Theis FJ, Meitinger T, Kronenberg F, Weidinger S, Wichmann HE, Suhre K, Wang-Sattler R, Adamski J, Illig T. Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS Genet. 2011 Aug;7(8):e1002215. Epub 2011 Aug 11.

1335 Molander A, Vengeliene V, Heilig M, Wurst W, Deussing JM, Spanagel R. Brain-Specific Inactivation of the Crhr1 Gene Inhibits Post-Dependent and Stress-Induced Alcohol Intake, but Does Not Affect Relapse-Like Drinking. Neuropsychopharmacology. 2012 Mar;37(4):1047-56. doi: 10.1038/npp.2011.297. Epub 2011 Nov 23.

1334 Moldt B, Miskey C, Staunstrup NH, Gogol-Döring A, Bak RO, Sharma N, Mátés L, Izsvák Z, Chen W, Ivics Z, Mikkelsen JG. Comparative Genomic Integration Profiling of Sleeping Beauty Transposons Mobilized With High Efficacy From Integrase-defective Lentiviral Vectors in Primary Human Cells. Mol Ther. 2011 Apr 5. [Epub ahead of print] PMID:21468003

1333 Moog U, Kutsche K, Kortüm F, Chilian B, Bierhals T, Apeshiotis N, Balg S, Chassaing N, Coubes C, Das S, Engels H, Van Esch H, Grasshoff U, Heise M, Isidor B, Jarvis J, Koehler U, Martin T, Oehl-Jaschkowitz B, Ortibus E, Pilz DT, Prabhakar P, Rappold G, Rau I, Rettenberger G, Schlüter G, Scott RH, Shoukier M, Wohlleber E, Zirn B, Dobyns WB, Uyanik G. Phenotypic spectrum associated with CASK loss-of-function mutations. J Med Genet. 2011 Nov;48(11):741-51. Epub 2011 Sep 27.

1332 Moskalev, E.A., Schubert, M. & Hoheisel, J.D. RNA-directed epigenomic reprogramming ? an emerging principle of a more targeted cancer therapy? Genes Chrom. Cancer 51, 105-110 (2012).

1331 Moskalev, E.A., Zavgorodnij, M.G., Majorova, S.P., Vorobjev, I.A., Jandaghi, P., Bure, I.V. & Hoheisel, J.D. Correction of PCR-bias in quantitative DNA methylation studies by means of cubic polynomial regression. Nucleic Acids Res. 2011 Jun;39(11):e77. Epub 2011 Apr 12.

1330 Moskvina V, Craddock N, Müller-Myhsok B, Kam-Thong T, Green E, Holmans P,Owen MJ, O'Donovan MC. An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction. Biol Psychiatry. 2011 Jul 15;70(2):198-203. doi.org/10.1016/j.biopsych.2011.01.034

1329 Muhle H, Mefford HC, Obermeier T, von Spiczak S, Eichler EE, Stephani U, Sander T, Helbig I. Absence seizures with intellectual disability as a phenotype of the 15q13.3 microdeletion syndrome. Epilepsia. 2011 Dec;52(12):e194-8. Epub 2011 Nov 2.

1328 Mühleisen TW, Basmanav FB, Forstner AJ, Mattheisen M, Priebe L, Herms S, Breuer R, Moebus S, Nenadic I, Sauer H, Mössner R, Maier W, Rujescu D, Ludwig M, Rietschel M, Nöthen MM, Cichon S. Resequencing and follow-up of neurexin 1 (NRXN1) in schizophrenia patients. Schizophr Res. 127:35-40, 2011. DOI: 10.1016/j.schres.2011.01.001

1327 Mulatero P, Tauber P, Zennaro MC, Monticone S, Lang K, Beuschlein F, Fischer E, Tizzani D, Pallauf A, Viola A, Amar L, Williams TA, Strom TM, Graf E, Bandulik S, Penton D, Plouin PF, Warth R, Allolio B, Jeunemaitre X, Veglio F, Reincke M. KCNJ5 mutations in European families with nonglucocorticoid remediable familial hyperaldosteronism. Hypertension. 2012 Feb;59(2):235-40. Epub 2011 Dec 27. PubMed PMID: 22203740.

1326 Mulaw MA, Krause AJ, Deshpande AJ, Krause LF, Rouhi A, La Starza R, Borkhardt A, Buske C, Mecucci C, Ludwig WD, Lottaz C, Bohlander SK. CALM/AF10-positive leukemias show upregulation of genes involved in chromatin assembly and DNA repair processes and of genes adjacent to the breakpoint at 10p12. Leukemia. 2011 Nov 8. doi: 10.1038/leu.2011.307. [Epub ahead of print]

1325 Müller T, Schrötter A, Loosse C, Helling S, Stephan C, Ahrens M, Uszkoreit J, Eisenacher M, Meyer HE, Marcus K. Sense and nonsense of pathway analysis software in proteomics. J Proteome Res. 2011 ;10(12):5398-408. PMID:21978018

1324 Müller TD, Tschöp MH, Jarick I, Ehrlich S, Scherag S, Herpertz-Dahlmann B, Zipfel S, Herzog W, de Zwaan M, Burghardt R, Fleischhaker C, Klampfl K, Wewetzer C, Herpertz S, Zeeck A, Tagay S, Burgmer M, Pfluger PT, Scherag A, Hebebrand J, Hinney A. Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa. Journal of Psychiatric Research 2011; 45:706-11

1323 Müller, UC and Zheng, H. Physiological Functions of APP Family Proteins. Cold Spring Harb Perspect Med doi:10.1101/cshperspect.a006288

1322 Munding JB, Adai AT, Maghnouj A, Urbanik A, Zollner H, Liffers ST, Chromik AM, Uhl W, Szafranska-Schwarzbach A, Tannapfel A, Hahn SA. Global microRNA expression profiling of microdissected tissues identifies miR-135b as a novel biomarker for pancreatic ductal adenocarcinoma. Int J Cancer. 2012 Jul 15;131(2):E86-95. doi: 10.1002/ijc.26466. Epub 2011 Nov 19.

1321 Murabito JM, White CC, Kavousi M, Sun YV, Feitosa MF, Nambi V, Lamina C, Schillert A, Coassin S, Bis JC, Broer L, Crawford DC, Franceschini N, Frikke-Schmidt R, Haun M, Holewijn S, Huffman JE, Hwang SJ, Kiechl S, Kollerits B, Montasser ME, Nolte IM, Rudock ME, Senft A, Teumer A, van der Harst P, Vitart V, Waite LL, Wood AR, Wassel CL, Absher DM, Allison MA, Amin N, Arnold A, Asselbergs FW, Aulchenko Y, Bandinelli S, Barbalic M, Boban M, Brown-Gentry K, Couper DJ, Criqui MH, Dehghan A, den Heijer M, Dieplinger B, Ding J, Dörr M, Espinola-Klein C, Felix SB, Ferrucci L, Folsom AR, Fraedrich G, Gibson Q, Goodloe R, Gunjaca G, Haltmayer M, Heiss G, Hofman A, Kieback A, Kiemeney LA, Kolcic I, Kullo IJ, Kritchevsky SB, Lackner KJ, Li X, Lieb W, Lohman K, Meisinger C, Melzer D, Mohler ER 3rd, Mudnic I, Mueller T, Navis G, Oberhollenzer F, Olin JW, O'Connell J, O'Donnell CJ, Palmas W, Penninx BW, Petersmann A, Polasek O, Psaty BM, Rantner B, Rice K, Rivadeneira F, Rotter JI, Seldenrijk A, Stadler M, Summerer M, Tanaka T, Tybjaerg-Hansen A, Uitterlinden AG, van Gilst WH, Vermeulen SH, Wild SH, Wild PS, Willeit J, Zeller T, Zemunik T, Zgaga L, Assimes TL, Blankenberg S, Boerwinkle E, Campbell H, Cooke JP, de Graaf J, Herrington D, Kardia SL, Mitchell BD, Murray A, Münzel T, Newman AB, Oostra BA, Rudan I, Shuldiner AR, Snieder H, van Duijn CM, Völker U, Wright AF, Wichmann HE, Wilson JF, Witteman JC, Liu Y, Hayward C, Borecki IB, Ziegler A, North KE, Cupples LA, Kronenberg F. Association between chromosome 9p21 variants and the ankle-brachial index identified by a meta-analysis of 21 genome-wide association studies. Circ Cardiovasc Genet. 2012 Feb 1;5(1):100-12. Epub 2011 Dec 23.

1320 Mustafa, S.A., Hoheisel, J.D. & Alhamdani, M.S.S. Secretome profiling with antibody microarrays. Mol. Biosyst. 7, 1795-1801 (2011).

1319 Nalls MA, Couper DJ, Tanaka T, van Rooij FJ, Chen MH, Smith AV, Toniolo D, Zakai NA, Yang Q, Greinacher A, Wood AR, Garcia M, Gasparini P, Liu Y, Lumley T, Folsom AR, Reiner AP, Gieger C, Lagou V, Felix JF, Völzke H, Gouskova NA, Biffi A, Döring A, Völker U, Chong S, Wiggins KL, Rendon A, Dehghan A, Moore M, Taylor K, Wilson JG, Lettre G, Hofman A, Bis JC, Pirastu N, Fox CS, Meisinger C, Sambrook J, Arepalli S, Nauck M, Prokisch H, Stephens J, Glazer NL, Cupples LA, Okada Y, Takahashi A, Kamatani Y, Matsuda K, Tsunoda T, Tanaka T, Kubo M, Nakamura Y, Yamamoto K, Kamatani N, Stumvoll M, Tönjes A, Prokopenko I, Illig T, Patel KV, Garner SF, Kuhnel B, Mangino M, Oostra BA, Thein SL, Coresh J, Wichmann HE, Menzel S, Lin J, Pistis G, Uitterlinden AG, Spector TD, Teumer A, Eiriksdottir G, Gudnason V, Bandinelli S, Frayling TM, Chakravarti A, van Duijn CM, Melzer D, Ouwehand WH, Levy D, Boerwinkle E, Singleton AB, Hernandez DG, Longo DL, Soranzo N, Witteman JC, Psaty BM, Ferrucci L, Harris TB, O'Donnell CJ, Ganesh SK. Multiple loci are associated with white blood cell phenotypes. PLoS Genetics 2011

1318 Nalls MA, Plagnol V, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Arepalli S, Barker R, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Bras JM, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper M, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson Ó, Harris C, van Hilten JJ, Hofman A, Hollenbeck A, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Lambert JC, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris HR, Morrison KE, Mudanohwo E, O'Sullivan S, Pearson J, Perlmutter JS, Pétursson H, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, Smith C, Spencer CC, Stefánsson H, Steinberg S, Stockton JD, Strange A, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Utterlinden AG, Velseboer D, Vidailhet M, Walker R, van de Warrenburg B, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Hardy J, Heutink P, Brice A, Gasser T, Singleton AB, Wood NW; International Parkinson Disease Genomics Consortium. Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet. 2011 Feb 19;377(9766):641-9.

1317 Naumann A, Söderhäll C, Fölster-Holst R, Baurecht H, Harde V, Müller-Wehling K, Rodríguez E, Ruether A, Franke A, Wagenpfeil S, Novak N, Mempel M, Kalali BN, Allgaeuer M, Koch J, Gerhard M, Melén E, Wahlgren CF, Kull I, Stahl C, Pershagen G, Lauener R, Riedler J, Doekes G, Scheynius A, Illig T, von Mutius E, Schreiber S, Kere J, Kabesch M, Weidinger S. A comprehensive analysis of the COL29A1 gene does not support a role in eczema. J Allergy Clin Immunol. 2011 Feb 24. [Epub ahead of print]

1316 Nebel A, Kleindorp R, Caliebe A, Nothnagel M, Blanché H, Junge O, Wittig M, Ellinghaus D, Flachsbart F, Wichmann HE, Meitinger T, Nikolaus S, Franke A, Krawczak M, Lathrop M, Schreiber S (2011). A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals. Mech Ageing Dev, 132(6-7):324-30.

1315 Nedelkova M, Maresca M, Fu J, Rostovskaya M, Chenna R, Thiede C, Anastassiadis K, Sarov M, Stewart AF. Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting. Nucleic Acids Res. 2011 Nov 1;39(20):e137. Epub 2011 Aug 18.

1314 Nischwitz S, Cepok S, Kroner A, Wolf C, Knop M, Müller-Sarnowski F, Pfister H, Rieckmann P, Hemmer B, Ising M, Uhr M, Bettecken T, Holsboer F, Müller-Myhsok B, Weber F. More CLEC16A gene variants associated with multiple sclerosis. Acta Neurol Scand. 2011 Jun;123(6):400-6. doi: 10.1111/j.1600-0404.2010.01421.x. Epub 2010 Sep 16. PubMed PMID: 20849399.

1313 Nitzsche A, Paszkowski-Rogacz M, Matarese F, Janssen-Megens E.M, Hubner NC, Schulz H,, de Vries I, Ding L, Huebner N, Mann M, Stunnenberg HG, Buchholz F. RAD21 cooperates with pluripotency transcription factors in the maintenance of embryonic stem cell identity. PLoS One. May 12;6(5):e19470.

1312 Noori, H. R. The effects of the acute administration of low-dosage ethanol on the phasic neurochemical oscillations of the basal ganglia. Math. Med. Biol., 2011, in press. Math Med Biol. 2011 May 4. [Epub ahead of print]

1311 Nothnagel M, Herrmann A, Wolf A, Schreiber S, Platzer M, Siebert R, Krawczak M, Hampe J. Technology-specific error signatures in the 1000 Genomes Project data. Hum Genet. 2011 Oct;130(4):505-16. Epub 2011 Feb 23.

1310 Nothnagel M, Wolf A, Herrmann A, Szafranski K, Vater I, Brosch M, Huse K, Siebert R, Platzer M, Hampe J, Krawczak M. Statistical inference of allelic imbalance from transcriptome data. Hum Mutat. 2011 Jan;32(1):98-106.

1309 Nuber S, Petrasch-Parwez E, Arias-Carrión O, Koch L, Kohl Z, Schneider J, Calaminus C, Dermietzel R, Samarina A, Boy J, Nguyen HP, Teismann P, Velavan TP, Kahle PJ, von Hörsten S, Fendt M, Krüger R, Riess O. Olfactory neuron-specific expression of A30P ?-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages. Neurobiol Dis 44:192-204

1308 O'Donnell CJ, Kavousi M, Smith AV, Kardia SL, Feitosa MF, Hwang SJ, Sun YV, Province MA, Aspelund T, Dehghan A, Hoffmann U, Bielak LF, Zhang Q, Eiriksdottir G, van Duijn CM, Fox CS, de Andrade M, Kraja AT, Sigurdsson S, Elias-Smale SE, Murabito JM, Launer LJ, van der Lugt A, Kathiresan S; CARDIoGRAM Consortium, Krestin GP, Herrington DM, Howard TD, Liu Y, Post W, Mitchell BD, O'Connell JR, Shen H, Shuldiner AR, Altshuler D, Elosua R, Salomaa V, Schwartz SM, Siscovick DS, Voight BF, Bis JC, Glazer NL, Psaty BM, Boerwinkle E, Heiss G, Blankenberg S, Zeller T, Wild PS, Schnabel RB, Schillert A, Ziegler A, Münzel TF, White CC, Rotter JI, Nalls M, Oudkerk M, Johnson AD, Newman AB, Uitterlinden AG, Massaro JM, Cunningham J, Harris TB, Hofman A, Peyser PA, Borecki IB, Cupples LA, Gudnason V, Witteman JC. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation. 2011 Dec 20; 124(25):2855-64.

1307 Oeltze S, Freiler W, Hillert R, Doleisch H, Preim B, Schubert W. Interactive, graph-based visual analysis of high-dimensional, multi-parameter fluorescence microscopy data in toponomics. IEEE Trans Vis Comput Graph. 2011 Dec;17(12):1882-91, doi:10.1109/TVCG.2011.217

1306 Ohlsson C, Wallaschofski H, Lunetta KL, Stolk L, Perry JR, Koster A, Petersen AK, Eriksson J, Lehtimäki T, Huhtaniemi IT, Hammond GL, Maggio M, Coviello AD; EMAS Study Group, Ferrucci L, Heier M, Hofman A, Holliday KL, Jansson JO, Kähönen M, Karasik D, Karlsson MK, Kiel DP, Liu Y, Ljunggren O, Lorentzon M, Lyytikäinen LP, Meitinger T, Mellström D, Melzer D, Miljkovic I, Nauck M, Nilsson M, Penninx B, Pye SR, Vasan RS, Reincke M, Rivadeneira F, Tajar A, Teumer A, Uitterlinden AG, Ulloor J, Viikari J, Völker U, Völzke H, Wichmann HE, Wu TS, Zhuang WV, Ziv E, Wu FC, Raitakari O, Eriksson A, Bidlingmaier M, Harris TB, Murray A, de Jong FH, Murabito JM, Bhasin S, Vandenput L, Haring R. Genetic determinants of serum testosterone concentrations in men. PLoS Genetics 2011

1305 Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, Trump S, Schumacher T, Jestaedt L, Schrenk D, Weller M, Jugold M, Guillemin GJ, Miller CL, Lutz C, Radlwimmer B, Lehmann I, von Deimling A, Wick W, Platten M. An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor. Nature. 2011 Oct 5;478(7368):197-203. doi: 10.1038/nature10491.

1304 Oppert JM, Sørensen TI, Hebebrand J, Woodward E, Blundell JE. Opportunities for European obesity research in the coming decade - a perspective from the European association for the study of obesity (EASO). Obes Facts. 2011;4(6):425-6. Epub 2011 Dec 30. PubMed PMID: 22248991.

1303 Otte DM, Sommersberg B, Kudin A, Guerrero C, Albayram O, Filiou MD, Frisch P, Yilmaz O, Drews E, Turck CW, Bilkei-Gorzó A, Kunz WS, Beck H, Zimmer A. N-acetyl cysteine treatment rescues cognitive deficits induced by mitochondrial dysfunction in G72/G30 transgenic mice. Neuropsychopharmacology. 2011 Oct;36(11):2233-43. doi: 10.1038/npp.2011.109.

1302 Pak C, Garshasbi M, Kahrizi K, Gross C, Apponi LH, Noto JJ, Kelly SM, Leung SW, Tzschach A, Behjati F, Abedini SS, Mohseni M, Jensen LR, Hu H, Huang B, Stahley SN, Liu G, Williams KR, Burdick S, Feng Y, Sanyal S, Bassell GJ, Ropers HH, Najmabadi H, Corbett AH, Moberg KH, Kuss AW. Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12390-5. Epub 2011 Jul 6.

1301 Papenfort K, Podkaminski D, Hinton JC, Vogel J. The ancestral SgrS RNA discriminates horizontally acquired Salmonella mRNAs through a single G-U wobble pair. PNAS 109(13):E757-64

1300 Park KS, Martelotto LG, Peifer M, Sos ML, Karnezis AN, Mahjoub MR, Bernard K, Conklin JF, Szczepny A, Yuan J, Guo R, Ospina B, Falzon J, Bennett S, Brown TJ, Markovic A, Devereux WL, Ocasio CA, Chen JK, Stearns T, Thomas RK, Dorsch M, Buonamici S, Watkins DN, Peacock CD, Sage J. A crucial requirement for Hedgehog signaling in small cell lung cancer. Nat Med. 2011 Oct 9;17(11):1504-8. doi: 10.1038/nm.2473

1299 Parkitna, J.R., Solecki, W., Go?embiowska, K., Tokarski, K., Kubik, J., Go?da, S., Novak, M., Parlato, R., Hess, G., Sprengel, R., et al. (2011). Glutamate input to noradrenergic neurons plays an essential role in the development of morphine dependence and psychomotor sensitization. Int. J. Neuropsychopharmacol. 1?15.

1298 Pasalic Z, Greif PA, Jurinovic V, Mulaw M, Kakadia PM, Tizazu B, Fröhlich-Archangelo L, Bohlander SK. FHL2 interacts with CALM and is highly expressed in acute erythroid leukemia. Blood Cancer Journal. 2011; November; 1(11): e42.

1297 Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, Ferreira MA, Alves AC, Thyssen CP, Albrecht E, Baurecht H, Feenstra B, Sleiman PMA, Hysi P, Warrington NM, Curjuric I, Myhre R, Curtin JA, Groen-Blokhuis MM, Kerkhof M, Sääf A, Franke A, Ellinghaus D, Fölster-Holst R, Dermitzakis E, Montgomery SB, Hartikainen AL, Pouta A, Pekkanen J, Blakemore AIF, Buxton JL, Kaakinen L, Duffy DL, Madden PA, Heath AC,Montgomery GW, Thompson PJ, Matheson MC, Le Souëf P, St Pourcain B, Davey Smith G, Henderson J, Kemp JP, Timpson NJ, Deloukas P, Ring SM, Wichmann HE, Müller M, Novak N, Klopp N, Rodríguez E, McArdle W,Linneberg A, Menné T, Nohr EA, Hofman A, Uitterlinden AG, van Duijn CM, Rivadeneira F, de Jongste JC, van derValk RJP, Wjst M, Jogi J, Geller F, Boyd HA, Murray JC, Kim C, Mentch F, March M, Mangino M, Spector TD, Bataille V, Pennell CE, Holt PE, Sly P, Tiesler CMT, Thiering E, Illig T, Imboden M, Nystad W, Simpson A, HottengaJJ, Postma D, Koppelman GH, Smit HA, Söderhäll C, Chawes B, Kreiner-Møller E, Bisgaard H, Melén E, Boomsma DI, Custovic A, Jacobsson B, Probst-Hensch NM, Palmer LJ, Glass D, Hakonarson H, Melbye M, JarvisDL, Gieger C, Strachan D, Martin NG, Jarvelin MR, Heinrich J, Evans DM, Weidinger S. Meta-analysis of genomewide association studies on atopic dermatitis identifies three novel risk loci. Nat Genet 2011; 44:187-192

1296 Paul FE; Hosp F; Selbach M. Analyzing protein-protein interactions by quantitative mass spectrometry. Methods : (2011-03-04)

1295 Peng C, Aron L, Klein R, Li M, Wurst W, Prakash N, Le W. Pitx3 is a critical mediator of GDNF-induced BDNF expression in nigrostriatal dopaminergic neurons. J Neurosci. 2011 Sep 7;31(36):12802-15.

1294 Pernhorst K, Raabe A, Niehusmann P, van Loo KM, Grote A, Hoffmann P, Cichon S, Sander T, Schoch S, Becker AJ. Promoter variants determine y-aminobutyric acid homeostasis-related gene transcription in human epileptic hippocampi. J Neuropathol Exp Neurol. 2011 Dec;70(12):1080-1088. PMID: 22082659

1293 Perschmann N, Hellmann JK, Frischknecht F, Spatz JP. Induction of malaria parasite migration by synthetically tunable microenvironments. Nano Lett. 2011 Oct;11:4468-7444.

1292 Petersen AK, Stark K, Musameh MD, Nelson CP, Römisch-Margl W, Kremer W, Raffler J, Krug S, Skurk T, Rist MJ, Daniel H, Hauner H, Adamski J, Tomaszewski M, Döring A, Peters A, Wichmann HE, Kaess BM, Kalbitzer HR, Huber F, Pfahlert V, Samani NJ, Kronenberg F, Dieplinger H, Illig T, Hengstenberg C, Suhre K, Gieger C, Kastenmüller G. Genetic associations with lipoprotein subfractions provide information on their biological nature. Hum Mol Genet. 2012 Mar 15;21(6):1433-43. Epub 2011 Dec 8

1291 Pfaffeneder T, Hackner B, Truss M, Münzel M, Müller M, Deiml CA, Hagemeier C, Carell T. The discovery of 5-formylcytosine in embryonic stem cell DNA. Angew Chem Int Ed Engl. 2011 Jul 25;50(31):7008-12. doi 10.1002/anie.201103899.

1290 Piccoli G, Condliffe SB, Bauer M, Giesert F, Boldt K, De Astis S, Meixner A, Sarioglu H, Vogt-Weisenhorn DM, Wurst W, Gloeckner CJ, Matteoli M, Sala C, Ueffing M. LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool. J Neurosci. 2011 Feb 9;31(6):2225-37.

1289 Pihlajamäki J, Lerin C, Itkonen P, Boes T, Floss T, Schroeder J, Dearie F, Crunkhorn S, Burak F, Jimenez-Chillaron JC, Kuulasmaa T, Miettinen P, Park PJ, Nasser I, Zhao Z, Zhang Z, Xu Y, Wurst W, Ren H, Morris AJ, Stamm S, Goldfine AB, Laakso M, Patti ME. Expression of the splicing factor gene SFRS10 is reduced in human obesity and contributes to enhanced lipogenesis. Cell Metabolism 2011 Aug 3;14(2):208-18.

1288 Plagnol V, Nalls MA, Bras JM, Hernandez DG, Sharma M, Sheerin UM, Saad M, Simón-Sánchez J, Schulte C, Lesage S, Sveinbjörnsdóttir S, Amouyel P, Arepalli S, Band G, Barker RA, Bellinguez C, Ben-Shlomo Y, Berendse HW, Berg D, Bhatia K, de Bie RM, Biffi A, Bloem B, Bochdanovits Z, Bonin M, Brockmann K, Brooks J, Burn DJ, Charlesworth G, Chen H, Chinnery PF, Chong S, Clarke CE, Cookson MR, Cooper JM, Corvol JC, Counsell C, Damier P, Dartigues JF, Deloukas P, Deuschl G, Dexter DT, van Dijk KD, Dillman A, Durif F, Dürr A, Edkins S, Evans JR, Foltynie T, Freeman C, Gao J, Gardner M, Gibbs JR, Goate A, Gray E, Guerreiro R, Gústafsson Ó, Harris C, Hellenthal G, van Hilten JJ, Hofman A, Hollenbeck A, Holton J, Hu M, Huang X, Huber H, Hudson G, Hunt SE, Huttenlocher J, Illig T, Jónsson PV, Langford C, Lees A, Lichtner P, Limousin P, Lopez G, Lorenz D, McNeill A, Moorby C, Moore M, Morris H, Morrison KE, Mudanohwo E, O'Sullivan SS, Pearson J, Pearson R, Perlmutter JS, Pétursson H, Pirinen M, Pollak P, Post B, Potter S, Ravina B, Revesz T, Riess O, Rivadeneira F, Rizzu P, Ryten M, Sawcer S, Schapira A, Scheffer H, Shaw K, Shoulson I, Sidransky E, de Silva R, Smith C, Spencer CC, Stefánsson H, Steinberg S, Stockton JD, Strange A, Su Z, Talbot K, Tanner CM, Tashakkori-Ghanbaria A, Tison F, Trabzuni D, Traynor BJ, Uitterlinden AG, Vandrovcova J, Velseboer D, Vidailhet M, Vukcevic D, Walker R, van de Warrenburg B, Weale ME, Wickremaratchi M, Williams N, Williams-Gray CH, Winder-Rhodes S, Stefánsson K, Martinez M, Donnelly P, Singleton AB, Hardy J, Heutink P, Brice A, Gasser T, Wood NW. International Parkinson's Disease Genomics Consortium (IPDGC); Wellcome Trust Case Control Consortium 2 (WTCCC2). A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet. 2011 Jun;7(6):e1002142.

1287 Porzelius C, Johannes M, Binder H, Beissbarth T. Leveraging external knowledge on molecular interactions in classification methods for risk prediction of patients. Biometrical J. 2011; 53(2):190-2011.

1286 Priebe L, Degenhardt FA, Herms S, Haenisch B, Mattheisen M, Nieratschker V, Weingarten M, Witt S, Breuer R, Paul T, Alblas M, Moebus S, Lathrop M, Leboyer M, Schreiber S, Grigoroiu-Serbanescu M, Maier W, Propping P, Rietschel M, Nöthen MM, Cichon S, Mühleisen TW. Genome-wide survey implicates the influence of copy number variants (CNVs) in the development of early-onset bipolar disorder. Mol Psychiatry. Epub ahead of print, 1 March 2011.

1285 Procaccini, C., Aitta-Aho, T., Jaako-Movits, K., Zharkovsky, A., Panhelainen, A., Sprengel, R., Linden, A.-M., and Korpi, E.R. (2011). Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout mice. Eur J Neurosci 33, 161?174.

1284 Proksch E, Weidinger S. New insights into the pathogenesis of sensitive skin. Hautarzt 2011; 62:900-5

1283 Puk O, Ahmad N, Wagner S, Hrabé de Angelis M, Graw J. First mutation in the ?A2-crystallin encoding gene is associated with small lenses and age-related cataracts. Invest Ophthalmol Vis Sci. 52(5):2571-6. doi: 10.1167/iovs.10-6443

1282 Puk O, Ahmad N, Wagner S, Hrabé de Angelis M, Graw J. Microphakia and congenital cataract formation in a novel Lim2C51R mutant mouse. Mol Vis. 17:1164-1171.  PMID: 21617753 http://www.molvis.org/molvis/v17/a131

1281 Puk O, Möller G, Geerlof A, Krowiorz K, Ahmad N, Wagner S, Adamski J, Hrabé de Angelis M, Graw J. The pathologic effect of a novel neomorphic Fgf9(Y162C) allele is restricted to decreased vision and retarded lens growth. PLoS One. 6(8):e23678. doi:10.1371/journal.pone.0023678

1280 Pütter C, Pechlivanis S, Nöthen MM, Jöckel KH, Wichmann HE, Scherag A. Missing heritability in the tails of quantitative traits? A simulation study on the impact of slightly altered true genetic models. Hum Hered. 2011;72(3):173-81.

1279 Quednow BB, Ettinger U, Mössner R, Rujescu D, Giegling I, Collier DA, Schmechtig A, Kühn KU, Möller HJ, Maier W, Wagner M, Kumari V. The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers. J Neurosci. 2011 May 4;31(18):6684-91.

1278 Querings S, Altmüller J, Ansén S, Zander T, Seidel D, Gabler F, Peifer M, Markert E, Stemshorn K, Timmermann B, Saal B, Klose S, Ernestus K, Scheffler M, Engel-Riedel W, Stoelben E, Brambilla E, Wolf J, Nürnberg P, Thomas RK. Benchmarking of mutation diagnostics in clinical lung cancer specimens. PLoS One. 2011 May 5;6(5):e19601.

1277 Raab M, Kappel S, Krämer A, Sanhaji M, Matthess Y, Kurunci-Csacsko E, Calzada-Wack J, Rathkolb B, Rozman J, Adler T, Busch DH, Esposito I, Fuchs H, Gailus-Durner V, Klingenspor M, Wolf E, Sänger N, Prinz F, Angelis MH, Seibler J, Yuan J, Bergmann M, Knecht R, Kreft B, Strebhardt K. Toxicity modelling of Plk1-targeted therapies in genetically engineered mice and cultured primary mammalian cells. Nat Commun. 2:395. doi: 10.1038/ncomms1395.

1276 Raabe CA, Hoe CH, Randau G, Brosius J, Tang TH, Rozhdestvensky TS. The rocks and shallows of deep RNA sequencing: Examples in the Vibrio cholerae RNome. RNA -A PUBLICATION OF THE RNA SOCIETY  Volume: 17   Issue: 7   Pages: 1357-1366   DOI: 10.1261/rna.2682311   Published: JUL 2011Times Cited: 2 (from Web of Science)

1275 Rafiq MA, Kuss AW, Puettmann L, Noor A, Ramiah A, Ali G, Hu H, Kerio NA, Xiang Y, Garshasbi M, Khan MA, Ishak GE, Weksberg R, Ullmann R, Tzschach A, Kahrizi K, Mahmood K, Naeem F, Ayub M, Moremen KW, Vincent JB, Ropers HH, Ansar M, Najmabadi H. Mutations in the alpha 1,2-mannosidase gene, MAN1B1, cause autosomal-recessive intellectual disability. Am J Hum Genet. 2011 Jul 15;89(1):176-82. Erratum in: Am J Hum Genet. 2011 Aug 12;89(2):348.

1274 Rakovic A, Grünewald A, Kottwitz J, Brüggemann N, Pramstaller PP, Lohmann K, Klein C. Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. PLoS One. 2011; 6(3):e16746.

1273 Ramm P, Bettscheider M, Beier D, Kalbitzer HR, Kremer W, Bogdahn U, Hau P, Aigner L, Beier CP. 1H-Nuclear Magnetic Resonance Spectroscopy of Glioblastoma Cancer Stem Cells. Stem Cells Dev. 2011 Mar 6. [Epub ahead of print] PubMed PMID: 21265608.

1272 Raszeja L, Maghnouj A, Hahn S, Metzler-Nolte N. A. Novel Organometallic ReI Complex with Favourable Properties for Bioimaging and Applicability in Solid-Phase Peptide Synthesis. ChemBioChem 2011;12:371-6.

1271 Raum E, Küpper-Nybelen J, Lamerz A, Hebebrand J, Herpertz-Dahlmann B, Brenner H. Tobacco smoke exposure before, during, and after pregnancy and risk of overweight at age 6. Obesity (Silver Spring). 2011 Dec;19(12):2411-7. doi: 10.1038/oby.2011.129. Epub 2011 May 26. PubMed PMID: 21617637.

1270 Rausch P, Rehman A, Kunzel S, Hasler R, Ott SJ, Schreiber S, Rosenstiel P, Franke A, Baines JF. Colonic mucosa-associated microbiota is influenced by an interaction of Crohn disease and FUT2 (Secretor) genotype. Proc Natl Acad Sci U S A 2011;108(47):19030-19035

1269 Rediger A, Piechowski CL, Yi CX, Tarnow P, Strotmann R, Grüters A, Krude H, Schöneberg T, Tschöp MH, Kleinau G, Biebermann H. Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors. J Biol Chem. 2011 Nov 11;286(45):39623-31. Epub 2011 Sep 22.

1268 Refojo D, Schweizer M, Kuehne C, Ehrenberg S, Thoeringer C, Vogl AM, Dedic N, Schumacher M, von Wolff G, Avrabos C, Touma C, Engblom D, Schütz G, Nave KA, Eder M, Wotjak CT, Sillaber I, Holsboer F, Wurst W, Deussing JM. Glutamatergic and dopaminergic neurons mediate anxiogenic and anxiolytic effects of CRHR1. Science. 2011 Sep 30;333(6051):1903-7. Epub 2011 Sep 1.

1267 Reginald K, Westritschnig K, Linhart B, Focke-Tejkl M, Jahn-Schmid B, Eckl-Dorna J, Heratizadeh A, Stöcklinger A, Balic N, Spitzauer S, Niederberger V, Werfel T, Thalhamer J, Weidinger S, Novak N, Ollert M, Hirschl AM, Valenta R. Staphylococcus aureus fibronectin-binding protein specifically binds IgE from patients with atopic dermatitis and requires antigen presentation for cellular immune responses. J Allergy Clin Immunol 2011; 128:82-91

1266 Rehman A, Sina C, Gavrilova O, Häsler R, Ott S, Baines JF, Schreiber S, Rosenstiel P. Nod2 is essential for temporal development of intestinal microbial communities. Gut. 2011 Oct;60(10):1354-62. Epub 2011 Mar 18.

1265 Reilly MP, Li M, He J, Ferguson JF, Stylianou IM, Mehta NN, Burnett MS, Devaney JM, Knouff CW, Thompson JR, Horne BD, Stewart AF, Assimes TL, Wild PS, Allayee H, Nitschke PL, Patel RS; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium, Martinelli N, Girelli D, Quyyumi AA, Anderson JL, Erdmann J, Hall AS, Schunkert H, Quertermous T, Blankenberg S, Hazen SL, Roberts R, Kathiresan S, Samani NJ, Epstein SE, Rader DJ. Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies. Lancet. 2011 Jan 29;377(9763):383-92.

1264 Reinehr T / Scherag A, Wang HJ, Roth CL, Kleber M, Scherag S, Boes T, Vogel C, Hebebrand J, Hinney A. Relationship between MTNR1B (melatonin receptor 1B gene) polymorphism rs10830963 and glucose levels in overweight children and adolescents. Pediatr Diabetes. 2011 Mar 3. doi: 10.1111/j.1399-5448.2010.00738.x. [Epub ahead of print] PubMed PMID: 21366812.

1263 Reinisch W, Sandborn WJ, Hommes DW, D'Haens G, Hanauer S, Schreiber S, Panaccione R, Fedorak RN, Tighe MB, Huang B, Kampman W, Lazar A, Thakkar R. Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut. 2011 Jun;60(6):780-7. Epub 2011 Jan 5

1262 Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, Riemenschneider M, Owen M, Harold D, Hollingworth P, Cellini E, Sorbi S, Nacmias B, Takeda M, Pericak-Vance MA, Haines JL, Younkin S, Williams J, van Broeckhoven C, Farrer LA, St George-Hyslop PH, Mayeux R. Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Arch Neurol. 2011 Jan;68(1):99-106.

1261 Remke M, Hielscher T, Korshunov A, Northcott PA, Bender S, Kool M, Westermann F, Benner A, Cin H, Ryzhova M, Sturm D, Witt H, Haag D, Toedt G, Wittmann A, Schöttler A, von Bueren AO, von Deimling A, Rutkowski S, Scheurlen W, Kulozik AE, Taylor MD, Lichter P, Pfister SM. FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma. J Clin Oncol. 2011 Oct 10;29(29):3852-61. Epub 2011 Sep 12.

1260 Remy S, Beck H, Yaari Y. Plasticity of voltage-gated ion channels in pyramidal cell dendrites. Curr Opin Neurobiol. 2010 Aug;20(4):503-9. Epub 2010 Aug 4.

1259 Rieder F, Lopez R, Franke A, Wolf A, Schleder S, Dirmeier A, Schirbel A, Rosenstiel P, Dotan N, Schreiber S, Rogler G, Klebl F. Characterization of changes in serum anti-glycan antibodies in Crohn?s disease - a longitudinal analysis. PLoS ONE 2011;6(5):e18172

1258 Rieker C, Dev KK, Lehnhoff K, Barbieri S, Ksiazek I, Kauffmann S, Danner S, Schell H, Boden C, Ruegg MA, Kahle PJ, van der Putten H, Shimshek DR. Neuropathology in mice expressing mouse alpha-synuclein. PLoS One. 2011;6(9):e24834.

1257 Rieker C, Engblom D, Kreiner G, Domanskyi A, Schober A, Stotz S, Neumann M, Yuan X, Grummt I, Schütz G, and Parlato R. Nucleolar disruption in dopaminergic neurons leads to oxidative damage and parkinsonism through repression of mammalian target of rapamycin signaling.J Neurosci 2011; 31:453-460.

1256 Rietschel M, Mattheisen M, Degenhardt F; GROUP Investigators; Genetic Risk and Outcome in Psychosis (GROUP Investigators), Kahn RS, Linszen DH, Os JV, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I, Mühleisen TW, Kirsch P, Esslinger C, Herms S, Demontis D, Steffens M, Strohmaier J, Haenisch B, Breuer R, Czerski PM, Giegling I, Strengman E, Schmael C, Mors O, Mortensen PB, Hougaard DM, Orntoft T, Kapelski P, Priebe L, Basmanav FB, Forstner AJ, Hoffmann P, Meier S, Nikitopoulos J, Moebus S, Alexander M, Mössner R, Wichmann HE, Schreiber S, Rivandeneira F, Hofman A, Uitterlinden AG, Wienker TF, Schumacher J, Hauser J, Maier W, Cantor RM, Erk S, Schulze TG; SGENE-plus Consortium; (Only those persons responsible for the samples of Replication 2 are listed), Stefansson H, Steinberg S, Gustafsson O, Sigurdsson E, Petursson H, Kong A, Stefansson K, Pietiläinen OP, Tuulio-Henriksson A, Paunio T, Lonnqvist J, Suvisaari J, Peltonen L, Ruggeri M, Tosato S, Walshe M, Murray R, Collier DA, Clair DS, Hansen T, Ingason A, Jakobsen KD, Duong L, Werge T, Melle I, Andreassen OA, Djurovic S, Bitter I, Réthelyi JM, Abramova L, Kaleda V, Golimbet V, Jönsson EG, Terenius L, Agartz I, Winkel RV, Kenis G, Hert MD, Veldink J, Wiuf C, Didriksen M, Craddock N, Owen MJ, O'Donovan MC, Børglum AD, Rujescu D, Walter H, Meyer-Lindenberg A, Nöthen MM, Ophoff RA, Cichon S. Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe. Mol Psychiatry. Epub ahead of print, 12 July 2011. DOI: 10.1038/ng.943

1255 Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St Clair D, Corvin A, Gurling H, Werge T, Rujescu D, Blackwood DH, Pato CN, Malhotra AK, Purcell S, Dudbridge F, Neale BM, Rossin L, Visscher PM, Posthuma D, Ruderfer DM, Fanous A, Stefansson H, Steinberg S, Mowry BJ, Golimbet V, De Hert M, Jönsson EG, Bitter I, Pietiläinen OP, Collier DA, Tosato S, Agartz I, Albus M, Alexander M, Amdur RL, Amin F, Bass N, Bergen SE, Black DW, Børglum AD, Brown MA, Bruggeman R, Buccola NG, Byerley WF, Cahn W, Cantor RM, Carr VJ, Catts SV, Choudhury K, Cloninger CR, Cormican P, Craddock N, Danoy PA, Datta S, de Haan L, Demontis D, Dikeos D, Djurovic S, Donnelly P, Donohoe G, Duong L, Dwyer S, Fink-Jensen A, Freedman R, Freimer NB, Friedl M, Georgieva L, Giegling I, Gill M, Glenthøj B, Godard S, Hamshere M, Hansen M, Hansen T, Hartmann AM, Henskens FA, Hougaard DM, Hultman CM, Ingason A, Jablensky AV, Jakobsen KD, Jay M, Jürgens G, Kahn RS, Keller MC, Kenis G, Kenny E, Kim Y, Kirov GK, Konnerth H, Konte B, Krabbendam L, Krasucki R, Lasseter VK, Laurent C, Lawrence J, Lencz T, Lerer FB, Liang KY, Lichtenstein P, Lieberman JA, Linszen DH, Lönnqvist J, Loughland CM, Maclean AW, Maher BS, Maier W, Mallet J, Malloy P, Mattheisen M, Mattingsdal M, McGhee KA, McGrath JJ, McIntosh A, McLean DE, McQuillin A, Melle I, Michie PT, Milanova V, Morris DW, Mors O, Mortensen PB, Moskvina V, Muglia P, Myin-Germeys I, Nertney DA, Nestadt G, Nielsen J, Nikolov I, Nordentoft M, Norton N, Nöthen MM, O'Dushlaine CT, Olincy A, Olsen L, O'Neill FA, Orntoft TF, Owen MJ, Pantelis C, Papadimitriou G, Pato MT, Peltonen L, Petursson H, Pickard B, Pimm J, Pulver AE, Puri V, Quested D, Quinn EM, Rasmussen HB, Réthelyi JM, Ribble R, Rietschel M, Riley BP, Ruggeri M, Schall U, Schulze TG, Schwab SG, Scott RJ, Shi J, Sigurdsson E, Silverman JM, Spencer CC, Stefansson K, Strange A, Strengman E, Stroup TS, Suvisaari J, Terenius L, Thirumalai S, Thygesen JH, Timm S, Toncheva D, van den Oord E, van Os J, van Winkel R, Veldink J, Walsh D, Wang AG, Wiersma D, Wildenauer DB, Williams HJ, Williams NM, Wormley B, Zammit S, Sullivan PF, O'Donovan MC, Daly MJ, Gejman PV; Schizophrenia Psychiatric Genome-Wide Association Study (GWAS) Consortium. Genome-wide association study identifies five new schizophrenia loci. Nat Genet. 2011 Sep 18;43(10):969-76. doi: 10.1038/ng.940.

1254 Ritzerfeld J, Remmele S, Wang T, Temmerman K, Brügger B, Wegehingel S, Tournaviti S, Strating JR, Wieland FT, Neumann B, Ellenberg J, Lawerenz C, Hesser J, Erfle H, Pepperkok R, Nickel W. Phenotypic profiling of the human genome reveals gene products involved in plasma membrane targeting of SRC kinases. Genome Research

1253 Rivas MA, Beaudoin M, Gardet A, Stevens C, Sharma Y, Zhang CK, Boucher G, Ripke S, Ellinghaus D, Burtt N, Fennell T, Kirby A, Latiano A, Goyette P, Green T, Halfvarson J, Haritunians T, Korn JM, Kuruvilla F, Lagacé C, Neale B, Lo KS, Schumm P, Törkvist L, Dubinsky MC, Brant SR, Silverberg MS, Duerr RH, Altshuler D, Gabriel S, Lettre G, Franke A, D?Amato M, McGovern DPB, Cho JH, Rioux JD, Xavier RJ, Daly MJ. Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease. Nature genetics 2011 Oct

1252 Rivera-Brugués N, Albrecht B, Wieczorek D, Schmidt H, Keller T, Göhring I, Ekici AB, Tzschach A, Garshasbi M, Franke K, Klopp N, Wichmann HE, Meitinger T, Strom TM, Hempel M. Cohen syndrome diagnosis using whole genome arrays. J Med Genet. 2011 Feb;48(2):136-40. Epub 2010 Oct 4

1251 Rizzato, C., Campa, D., Giese, N., Werner, J., Rachakonda, S.P., Kumar, R., Schanné, M., Greenhalf, W., Costello, E., Khaw, K.T., Key, T.J., Siddiq, A., Lorenzo-Bermejo, J., Burwinkel, B., Neoptolemos, J.P., Büchler, M.W., Hoheisel, J.D., Bauer, A. & Canzian, F. Pancreatic cancer susceptibility loci and their role in survival. PLoS ONE 6, e27921 (2011).

1250 Rode, H., M.L. Sos, C. Grütter, S. Heynck, J.R. Simard, D. Rauh. Synthesis and biological evaluation of 7-substituted-1-(3-bromophenylamino) isoquinoline-4-carbonitriles as inhibitors of Myosine Light Chain Kinase and Epidermal Growth Factor Receptor. Bioorg Med Chem, 2011, 19(1):429-39.

1249 Rodríguez E, Eyerich K, Weidinger S. Genetics of common chronic inflammatory skin diseases : An update on atopic dermatitis and psoriasis. Hautarzt. 2011 Feb;62(2):107-118

1248 Roeske D, Ludwig KU, Neuhoff N, Becker J, Bartling J, Bruder J, Brockschmidt FF, Warnke A, Remschmidt H, Hoffmann P, Müller-Myhsok B, Nöthen MM, Schulte-Körne G. First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children. Mol Psychiatry. 2011 Jan;16(1):97-107. doi:10.1038/mp.2009.102

1247 Roesli C, Fugmann T, Borgia B, Schliemann C, Neri D, Jucker M.The accessible cerebral vascular proteome in a mouse model of cerebral ß-amyloidosis. Journal of Proteomics 74: 539-546

1246 Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Hölter SM, Vogt-Weisenhorn DM, Liss B, Wurst W, Lie DC, Thal DR, Biber K, Rudolph KL. Telomere shortening reduces Alzheimer's disease amyloid pathology in mice. Brain. 2011 Jul;134(Pt 7):2044-56. Epub 2011 Jun 14.

1245 Romanos M, Buske-Kirschbaum A, Fölster-Holst R, Gerlach M, Weidinger S, Schmitt J. Itches and scratches ? is there a link between eczema, ADHD, sleep disruption and food hypersensitivity? Allergy 2011; 66:1407-9

1244 Ros-Bernal F, Hunot S, Herrero MT, Parnadeau S, Corvol JC, Lu L, Alvarez-Fischer D, Carrillo-de Sauvage MA, Saurini F, Coussieu C, Kinugawa K, Prigent A, Höglinger G, Hamon M, Tronche F, Hirsch EC, Vyas S. Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism. Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6632-7. Epub 2011 Apr 5.

1243 Rosenberger A, Rössler U, Hornhardt S, Sauter W, Bickeböller H, Wichmann HE, Gomolka M. Validation of a fully automated COMET assay: 1.75 million single cells measured over a 5 year period. DNA REPAIR 2011

1242 Rösler TW, Depboylu C, Arias-Carrión O, Wozny W, Carlsson T, Höllerhage M, Oertel WH, Schrattenholz A, Höglinger GU. Biodistribution and brain permeability of the extracellular domain of neuregulin-1-?1. Neuropharmacology. 2011 Dec;61(8):1413-8. Epub 2011 Aug 31. doi:10.1016/j.neuropharm.2011.08.033

1241 Ross OA, Soto-Ortolaza AI, Aasly JO, Abahuni N, Annesi G, Bacon J, Bardien S, Bozi M, Brice A, Brighina L, van Broeckhoven C,Carr J, Chartier-Harlin MC, Dardiotis E, Diehl N, Ferrarese C, Ferraris A, Friske B, Gibson JM, Gibson R, Hadjigeorgiou GM, Hattori N, Heckman MG, Jasinska-Myga, B, Jeon BS, Kim YJ, Klein C, Krüger R, Kyratzi E, Lesage S, Lin CH, Lynch T, Maraganore DM,  Mellick G, Nilsson C, Nuytemans K, Opala G, Sup Park S, Pedersen NL, Puschmann A, Quattrone A, Sharma M, Silburn PA, Sohn YH, Stefanis L, Tadic V, Tomiyama H, Uitti R, Valente EM, van de Loo S, Vassilatis D, Vilariño-Güell C, White LR, Wirdefelt K, Wszolek ZK, Wu RM and Farrer MJ on behalf of the Genetic Epidemiology Of Parkinson?s Disease (GEOPD) consortium. (2011) LRRK2 exonic variants and susceptibility to Parkinson?s disease. Lancet Neurology 10: 898-908

1240 Rossin EJ, Lage K, Raychaudhuri S, Xavier RJ, Tatar D, Benita Y; International Inflammatory Bowel Disease Genetics Constortium, Cotsapas C, Daly MJ. Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet. 2011 Jan 13;7(1):e1001273

1239 Rosskopf D, Schwahn C, Neumann F, Bornhorst A, Rimmbach C, Mischke M, Wolf S, Geissler I, Kocher T, Grabe HJ, Nauck M, Hebebrand J, Kroemer HK, Friedrich N, Völzke H, Wallaschofski H. The growth hormone-IGF-I axis as a mediator for the association between FTO variants and body mass index: results of the Study of Health in Pomerania. Int J Obes (Lond). 2011 Mar;35(3):364-72. Epub 2010 Aug 24.PMID: 20733585

1238 Röther S. & Meister G. Small RNAs derived from longer non-coding RNAs. Biochimie, 93(11): 1905-1915.

1237 Rotival M, Zeller T, Wild PS, Maouche S, Szymczak S, Schillert A, Castagné R, Deiseroth A, Proust C, Brocheton J, Godefroy T, Perret C, Germain M, Eleftheriadis M, Sinning CR, Schnabel RB, Lubos E, Lackner KJ, Rossmann H,Münzel T, Rendon A; Cardiogenics Consortium, Erdmann J, Deloukas P, Hengstenberg C, Diemert P, Montalescot G, Ouwehand WH, Samani NJ, Schunkert H, Tregouet DA, Ziegler A, Goodall AH, Cambien F, Tiret L, Blankenberg S. Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans. PLoS Genet. 2011 Dec;7(12):e1002367

1236 Rudolph A, Sainz J, Hein R, Hoffmeister M, Frank B, Försti A, Brenner H, Hemminki K, Chang-Claude J.Modification of menopausal hormone therapy associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes. Endocr Relat Cancer 2011;18:371-384. doi 10.4103/1477-3163.78268

1235 Rupp A-K, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marmé F, Sültmann H, Altevogt P. Loss of EpCAM expression in breast cancer derived serum exosomes: role of proteolytic cleavage. Gynecol Oncol. 2011 Aug;122(2):437-46. Epub 2011 May 20

1234 Saarikangas J, Mattila PK, Varjosalo M, Bovellan M, Hakanen J, Calzada-Wack J, Tost M, Jennen L, Rathkolb B, Hans W, Horsch M, Hyvönen ME, Perälä N, Fuchs H, Gailus-Durner V, Esposito I, Wolf E, Hrabé de Angelis M, Frilander MJ, Savilahti H, Sariola H, Sainio K, Lehtonen S, Taipale J, Salminen M, Lappalainen P. Missing-in metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. J Cell Science 124, 1245-1255 DOI:10.1242/jcs.082610

1233 Sainz J, Rudolph A, Hein R, Hoffmeister M, Buch S, von Schönfels W, Hampe J, Schafmayer C, Völzke H, Frank B, Brenner H, Försti A, Hemminki K, Chang-Claude J. Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk. Endocr Relat Cancer. 2011 Mar 9;18(2):265-76. Print 2011 Apr.

1232 Salem S, Bruck H, Bahlmann FH, Peter M, Passlick-Deetjen J, Kretschmer A, Steppan S, Volsek M, Kribben A, Nierhaus M, Jankowski V, Zidek W, Jankowski J. Relationship between magnesium and clinical biomarkers on inhibition of vascular calcification. Am J Nephrol. 2012;35(1):31-9. Epub 2011 Dec 15.

1231 Sandborn WJ, Colombel JF, Schreiber S, Plevy SE, Pollack PF, Robinson AM, Chao J, Mulani P. Dosage adjustment during long-term adalimumab treatment for Crohn's disease: clinical efficacy and pharmacoeconomics. Inflamm Bowel Dis. 2011 Jan;17(1):141-51. doi: 10.1002/ibd.21328

1230 Sandborn WJ, Schreiber S, Feagan BG, Rutgeerts P, Younes ZH, Bloomfield R, Coteur G, Guzman JP, D'Haens GR. Certolizumab pegol for active Crohn's disease: a placebo-controlled, randomized trial. Clin Gastroenterol Hepatol. 2011 Aug;9(8):670-678.e3. Epub 2011 May 13

1229 Sanderson, D.J., Hindley, E., Smeaton, E., Denny, N., Taylor, A., Barkus, C., Sprengel, R., Seeburg, P.H., and Bannerman, D.M. (2011a). Deletion of the GluA1 AMPA receptor subunit impairs recency-dependent object recognition memory. Learn Mem 18, 181?190.

1228 Sanderson, D.J., Sprengel, R., Seeburg, P.H., and Bannerman, D.M. (2011b). Deletion of the GluA1 AMPA receptor subunit alters the expression of short-term memory. Learn Mem 18, 128?131.

1227 Sanson M, Hosking FJ, Shete S, Zelenika D, Dobbins SE, Ma Y, Enciso-Mora V, Idbaih A, Delattre JY, Hoang-Xuan K, Marie Y, Boisselier B, Carpentier C, Wang XW, Di Stefano AL, Labussière M, Gousias K, Schramm J, Boland A, Lechner D, Gut I, Armstrong G, Liu Y, Yu R, Lau C, Di Bernardo MC, Robertson LB, Muir K, Hepworth S, Swerdlow A, Schoemaker MJ, Wichmann HE, Müller M, Schreiber S, Franke A, Moebus S, Eisele L, Försti A, Hemminki K, Lathrop M, Bondy M, Houlston RS, Simon M. Chromosome 7p11.2 (EGFR) variation influences glioma risk. Hum Mol Genet. 2011

1226 Schaefer AS, Richter GM, Dommisch H, Reinartz M, Nothnagel M, Noack B, Laine ML, Folwaczny M, Groessner-Schreiber B, Loos BG, Jepsen S, Schreiber S. CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection. J Med Genet. 2011 Jan;48(1):38-47. Epub 2010 Oct 26. PMID: 20978019

1225 Schäfer N, Wagener A, Hantschel C, Mauel S, Gruber AD, Brockmann GA. High insulin and IGF-I levels maintain glucose homeostasis in the Berlin Fat Mouse Inbred line. Growth Factors 2011; 29(6):298-309

1224 Schelhorn SE, Mestre J, Albrecht M, Zotenko E. Inferring physical protein contacts from large-scale purification data of protein complexes. Mol Cell Proteomics. 2011 Jun;10(6):M110.004929.

1223 Scherag A, Kleber M, Boes T, Kolbe AL, Ruth A, Grallert H, Illig T, Heid IM, Toschke AM, Grau K; NUGENOB Consortium, Sørensen TI, Hebebrand J, Hinney A, Reinehr T. SDCCAG8 obesity alleles and reduced weight loss after a lifestyle intervention in overweight children and adolescents. Obesity (Silver Spring). 2012 Feb;20(2):466-70. doi: 10.1038/oby.2011.339. Epub 2011 Nov 17.

1222 Schjeide BM, Schnack C, Lambert JC, Lill CM, Kirchheiner J, Tumani H, Otto M, Tanzi RE, Lehrach H, Amouyel P, von Arnim CA, Bertram L. The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels. Arch Gen Psychiatry. 2011 Feb;68(2):207-13.

1221 Schmidt M, Petry IB, Böhm D, Lebrecht A, von Törne C, Gebhard S, Gerhold-Ay A, Cotarelo C, Battista M, Schormann W, Freis E, Selinski S, Ickstadt K, Rahnenführer J, Sebastian M, Schuler M, Koelbl H, Gehrmann M, Hengstler JG. Ep-CAM RNA expression predicts metastasis free survival in three cohorts of untreated node negative breast cancer. Breast Cancer Res Trea. 2011 Feb; 125(3):637-46

1220 Schmidt MV, Schülke JP, Liebl C, Stiess M, Avrabos C, Bock J, Wochnik GM, Davies HA, Zimmermann N, Scharf SH, Trümbach D, Wurst W, Zieglgänsberger W, Turck C, Holsboer F, Stewart MG, Bradke F, Eder M, Müller MB, Rein T. Tumor suppressor down-regulated in renal cell carcinoma 1 (DRR1) is a stress-induced actin bundling factor that modulates synaptic efficacy and cognition. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17213-8. Epub 2011 Oct 3.

1219 Schmidt, R., Jacak, J., Schirwitz, C., Stadler, V., Michel, G., Marmé, N., Schütz, G.J., Hoheisel, J.D. & Knemeyer, J.-P. Single-molecule detection on a protein-array assay platform for the exposure of a tuberculosis antigen. J Proteome Res. 10, 1316-1322 (2011).

1218 Schmitt, J., A. Keller, N. Nourkami-Tutdibi, S. Heisel, N. Habel, P. Leidinger, N. Ludwig, M. Gessler, N. Graf, F. Berthold, H.P. Lenhof, and E. Meese. Autoantibody signature differentiates wilms tumor patients from neuroblastoma patients. PLoS One, 2011. 6(12): p. e28951.

1217 Schmitz G, Breithaupt P, Scheidegger N, Cario G, Bonapace L, Meissner B, Mirkowska P, Tchinda J, Niggli FK, Stanulla M, Schrappe M, Schrauder A, Bornhauser BC, Bourquin JP. Xenografts of highly resistant leukemia recapitulate the clonal composition of the leukemogenic compartment. Blood. 2011 Aug 18;118(7):1854-64. Epub 2011 Jun 13.

1216 Schnabel RB, Kerr KF, Lubitz SA, Alkylbekova EL, Marcus GM, Sinner MF, Magnani JW, Wolf PA, Deo R, Lloyd-Jones DM, Lunetta KL, Mehra R, Levy D, Fox ER, Arking DE, Mosley TH, Müller-Nurasyid M, Young TR, Wichmann HE, Seshadri S, Farlow DN, Rotter JI, Soliman EZ, Glazer NL, Wilson JG, Breteler MM, Sotoodehnia N, Newton-Cheh C, Kääb S, Ellinor PT, Alonso A, Benjamin EJ, Heckbert SR; Candidate Gene Association Resource (CARe) Atrial Fibrillation/Electrocardiography Working Group. Large-scale candidate gene analysis in whites and African Americans identifies IL6R polymorphism in relation to atrial fibrillation: the National Heart, Lung, and Blood Institute's Candidate Gene Association Resource (CARe) project. Circulation-Cardiovascular Genetics. 2011

1215 Schnütgen F , Franziska Ehrmann, Ina Poser, Nina C Hubner, Jens Hansen, Thomas Floss, Ingrid deVries, Wolfgang Wurst, Anthony Hyman, Matthias Mann & Harald von Melchner. Resources for proteomics in mouse embryonic stem cells. Nature Methods 2011; 8:103?104. doi:10.1038/nmeth0211-103

1214 Schnütgen F, Ehrmann F, Ruiz-Noppinger P, and von Melchner H. High throughput gene trapping and postinsertional modifications of gene trap alleles. Methods 53, 347-355 (2011)

1213 Schönberger A, Gembe E, Grote A, Witt JA, Elger CE, Bien CG, Urbach H, Becker AJ, Niehusmann P. Genetic analysis of tuberous-sclerosis genes 1 and 2 in nonlesional focal epilepsy.Epilepsy Behav. 2011 Jul;21(3):233-7. Epub 2011 May 8. PMID: 21555252

1212 Schosser A, Butler AW, Ising M, Perroud N, Uher R, Ng MY, Cohen-Woods S, Craddock N, Owen MJ, Korszun A, Jones L, Jones I, Gill M, Rice JP, Maier W, Mors O, Rietschel M, Lucae S, Binder EB, Preisig M, Perry J, Tozzi F, Muglia P, Aitchison KJ, Breen G, Craig IW, Farmer AE, Müller-Myhsok B, McGuffin P, Lewis CM. Genomewide association scan of suicidal thoughts and behaviour in major depression. PLoS One. 2011;6(7)

1211 Schubert W, Gieseler A, Krusche A, Serocka P, Hillert R. Next-generation biomarkers based on 100-parameter functional super-resolution microscopy TIS. N Biotechnol. 2011 Dec 21. (Epub ahead of print), doi:10.1016/j.nbt.2011.12.004

1210 Schuchardt M, Prüfer J, Prüfer N, Wiedon A, Huang T, Chebli M, Jankowski V, Jankowski J, Schäfer-Korting M, Zidek W, van der Giet M, Tölle M. The endothelium-derived contracting factor uridine adenosine tetraphosphate induces P2Y(2)-mediated pro-inflammatory signaling by monocyte chemoattractant protein-1 formation. J Mol Med (Berl). 2011

1209 Schuhmacher A, Mössner R, Höfels S, Pfeiffer U, Guttenthaler V, Wagner M, Schwab SG, Maier W, Zobel A. PCLO rs2522833 modulates HPA system response to antidepressant treatment in major depressive disorder. Int J Neuropsychopharmacol. 2011 Mar;14(2):237-45.

1208 Schulte JH., H.S. Bachmann, B. Brockmeyer, K. Depreter, A. Oberthur, S. Ackermann, Y. Kahlert, K. Pajtler, J. Theissen, F. Westermann, J. Vandesompele, F. Speleman, F. Berthold, A. Eggert, B. Brors, B. Hero, A. Schramm, and M. Fischer. High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma. Clin Cancer Res, 2011. 17(15): p. 5082-92.

1207 Schulte LN, Eulalio A, Mollenkopf HJ, Reinhardt R, Vogel J. Analysis of the host microRNA response to Salmonella uncovers the control of major cytokines by the let-7 family. EMBO Journal 30(10):1977-89 (commentary in EMBO J 30(10):1977-9).

1206 Schultz CC, Nenadic I, Koch K, Wagner G, Roebel M, Schachtzabel C, Mühleisen TW, Nöthen MM, Cichon S, Deufel T, Kiehntopf M, Rietschel M, Reichenbach JR, Sauer H, Schlösser RG. Reduced cortical thickness is associated with the glutamatergic regulatory gene risk variant DAOA Arg30Lys in schizophrenia. Neuropsychopharmacology. 2011 Jul;36(8):1747-53. doi:10.1038/npp.2011.56. Epub 2011 Apr 20.

1205 Schulz N, Himmelbauer H, Rath M, van Weeghel M, Houten S, Kulik W, Suhre K, Scherneck S, Vogel H, Kluge R, Wiedmer P, Joost HG, Schürmann A. Role of Medium- and Short-Chain L-3-Hydroxyacyl-CoA Dehydrogenase in the Regulation of Body Weight and Thermogenesis. Endocrinology. 152:4641-4651. (2011)

1204 Schumann G, Coin LJ, Lourdusamy A, Charoen P, Berger KH, Stacey D, Desrivières S, Aliev FA, Khan AA, Amin N, Aulchenko YS, Bakalkin G, Bakker SJ, Balkau B, Beulens JW, Bilbao A, de Boer RA, Beury D, Bots ML, Breetvelt EJ, Cauchi S, Cavalcanti-Proença C, Chambers JC, Clarke TK, Dahmen N, de Geus EJ, Dick D, Ducci F, Easton A, Edenberg HJ, Esk T, Fernández-Medarde A, Foroud T, Freimer NB, Girault JA, Grobbee DE, Guarrera S, Gudbjartsson DF, Hartikainen AL, Heath AC, Hesselbrock V, Hofman A, Hottenga JJ, Isohanni MK, Kaprio J, Khaw KT, Kuehnel B, Laitinen J, Lobbens S, Luan J, Mangino M, Maroteaux M, Matullo G, McCarthy MI, Mueller C, Navis G, Numans ME, Núñez A, Nyholt DR, Onland-Moret CN, Oostra BA, O'Reilly PF, Palkovits M, Penninx BW, Polidoro S, Pouta A, Prokopenko I, Ricceri F, Santos E, Smit JH, Soranzo N, Song K, Sovio U, Stumvoll M, Surakk I, Thorgeirsson TE, Thorsteinsdottir U, Troakes C, Tyrfingsson T, Tönjes A, Uiterwaal CS, Uitterlinden AG, van der Harst P, van der Schouw YT, Staehlin O, Vogelzangs N, Vollenweider P, Waeber G, Wareham NJ, Waterworth DM, Whitfield JB, Wichmann EH, Willemsen G, Witteman JC, Yuan X, Zhai G, Zhao JH, Zhang W, Martin NG, Metspalu A, Doering A, Scott J, Spector TD, Loos RJ, Boomsma DI, Mooser V, Peltonen L, Stefansson K, van Duijn CM, Vineis P, Sommer WH, Kooner JS, Spanagel R, Heberlein UA, Jarvelin MR, Elliott P. Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7119-24. Epub 2011 Apr 6.

1203 Schunkert H, König IR, Kathiresan S, Reilly MP, Assimes TL, Holm H, Preuss M, Stewart AF, Barbalic M, Gieger C, Absher D, Aherrahrou Z, Allayee H, Altshuler D, Anand SS, Andersen K, Anderson JL, Ardissino D, Ball SG, Balmforth AJ, Barnes TA, Becker DM, Becker LC, Berger K, Bis JC, Boekholdt SM, Boerwinkle E, Braund PS, Brown MJ, Burnett MS, Buysschaert I; Cardiogenics, Carlquist JF, Chen L, Cichon S, Codd V, Davies RW, Dedoussis G, Dehghan A, Demissie S, Devaney JM, Diemert P, Do R, Doering A, Eifert S, Mokhtari NE, Ellis SG, Elosua R, Engert JC, Epstein SE, de Faire U, Fischer M, Folsom AR, Freyer J, Gigante B, Girelli D, Gretarsdottir S, Gudnason V, Gulcher JR, Halperin E, Hammond N, Hazen SL, Hofman A, Horne BD, Illig T, Iribarren C, Jones GT, Jukema JW, Kaiser MA, Kaplan LM, Kastelein JJ, Khaw KT, Knowles JW, Kolovou G, Kong A, Laaksonen R, Lambrechts D, Leander K, Lettre G, Li M, Lieb W, Loley C, Lotery AJ, Mannucci PM, Maouche S, Martinelli N, McKeown PP, Meisinger C, Meitinger T, Melander O, Merlini PA, Mooser V, Morgan T, Mühleisen TW, Muhlestein JB, Münzel T, Musunuru K, Nahrstaedt J, Nelson CP, Nöthen MM, Olivieri O, Patel RS, Patterson CC, Peters A, Peyvandi F, Qu L, Quyyumi AA, Rader DJ, Rallidis LS, Rice C, Rosendaal FR, Rubin D, Salomaa V, Sampietro ML, Sandhu MS, Schadt E, Schäfer A, Schillert A, Schreiber S, Schrezenmeir J, Schwartz SM, Siscovick DS, Sivananthan M, Sivapalaratnam S, Smith A, Smith TB, Snoep JD, Soranzo N, Spertus JA, Stark K, Stirrups K, Stoll M, Tang WH, Tennstedt S, Thorgeirsson G, Thorleifsson G, Tomaszewski M, Uitterlinden AG, van Rij AM, Voight BF, Wareham NJ, Wells GA, Wichmann HE, Wild PS, Willenborg C, Witteman JC, Wright BJ, Ye S, Zeller T, Ziegler A, Cambien F, Goodall AH, Cupples LA, Quertermous T, März W, Hengstenberg C, Blankenberg S, Ouwehand WH, Hall AS, Deloukas P, Thompson JR, Stefansson K, Roberts R, Thorsteinsdottir U, O'Donnell CJ, McPherson R, Erdmann J; CARDIoGRAM Consortium, Samani NJ. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet. 2011 Mar 6 ;43(4):333-8.

1202 Schwanhäusser, B., Busse, D., Li, N., Dittmar, G., Schuchhardt, J., Wolf, J., Chen, W., Selbach, M. (2011). Global quantification of mammalian gene expression control. Nature. 2011 May 19;473(7347):337-42.

1201 Schweiger M.R., Kerick M., Timmermann B. and M.Isau T. The power of NGS technologies to delineate the genome organization in cancer: From mutations to structural variations and epigenetic alterations. Cancer Metastasis Rev. 2011 Jan 27.

1200 Seebacher J, Gavin AC. SnapShot: Protein-protein interaction networks. Cell. 2011;144(6):1000. PMID:21414489

1199 Seifried C, Weise L, Hartmann R, Gasser T, Baudrexel S, Szelényi A, van de Loo S, Steinmetz H, Seifert V, Roeper J, Hilker R. Intraoperative microelectrode recording for the delineation of subthalamic nucleus topography in Parkinson's disease. Brain Stimul. 2011 Jul 8

1198 Setty P, Gessi M, Waha A, Hammes J, El-Maarri O, Pietsch T and Waha A. Sensitive determination of BRAF copy number in clinical samples by Pyrosequencing. Diagn Mol Pathol. 2011 Sep;20(3):148-57. doi: 10.1097/PDM.0b013e3182143817.

1197 Shalapour S, Hof J, Kirschner-Schwabe R, Bastian L, Eckert C, Prada J, Henze G, von Stackelberg A, Seeger K. High VLA-4 expression is associated with adverse outcome and distinct gene expression changes in childhood B-cell precursor acute lymphoblastic leukemia at first relapse. Haematologica. 2011 Nov; 96(11):1627-35. doi 10.3324/haematol.2011.047993

1196 Sharma M, Maraganore DM, Ioannidis JP, Riess O, Aasly JO, Annesi G, Abahuni N, Bentivoglio AR, Brice A, Van Broeckhoven C, Chartier-Harlin MC, Destée A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Gispert S, Hattori N, Jasinska-Myga B, Klein C, Lesage S, Lynch T, Lichtner P, Lambert JC, Lang AE, Mellick GD, De Nigris F, Opala G, Quattrone A, Riva C, Rogaeva E, Ross OA, Satake W, Silburn PA, Theuns J, Toda T, Tomiyama H, Uitti RJ, Wirdefeldt K, Wszolek Z, Gasser T, Krüger R; Genetic Epidemiology of Parkinson's Disease Consortium. Role of sepiapterin reductase gene at the PARK3 locus in Parkinson's disease. Neurobiol Aging. 2011 Nov;32(11):2108.e1-5.

1195 Shi Y, Li Z, Xu Q, Wang T, Li T, Shen J, Zhang F, Chen J, Zhou G, Ji W, Li B, Xu Y, Liu D, Wang P, Yang P, Liu B, Sun W, Wan C, Qin S, He G, Steinberg S, Cichon S, Werge T, Sigurdsson E, Tosato S, Palotie A, Nöthen MM, Rietschel M, Ophoff RA, Collier DA, Rujescu D, Clair DS, Stefansson H, Stefansson K, Ji J, Wang Q, Li W, Zheng L, Zhang H, Feng G, He L. Common variants on 8p12 and 1q24.2 confer risk of schizophrenia. Nat Genet. 2011 Oct 30;43(12):1224-7. doi: 10.1038/ng.980

1194 Shochat C, Tal N, Bandapalli OR, Palmi C, Ganmore I, te Kronnie G, Cario G, Cazzaniga G, Kulozik AE, Stanulla M, Schrappe M, Biondi A, Basso G, Bercovich D, Muckenthaler MU, Izraeli S. Gain-of-function mutations in interleukin-7 receptor-alpha (il7r) in childhood acute lymphoblastic leukemias. J Exp Med 2011;208:901-908

1193 Sibbing D*, Pfeufer A*, Perisic T*, Mannes AM, Fritz-Wolf K, Unwin S, Sinner MF, Gieger C, Gloeckner CJ, Wichmann HE, Kremmer E, Schäfer Z, Walch A, Hinterseer M, Näbauer M, Kääb S, Kastrati A, Schömig A, Meitinger T, Bornkamm GW, Conrad M, von Beckerath N. Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy. Eur Heart J. 2011 Jan 18. [Epub ahead of print]

1192 Sklar P, Ripke S, Scott LJ, Andreassen OA, Cichon S, Craddock N, Edenberg HJ, Nurnberger JI Jr, Rietschel M, Blackwood D, Corvin A, Flickinger M, Guan W, Mattingsdal M, McQuillin A, Kwan P, Wienker TF, Daly M, Dudbridge F, Holmans PA, Lin D, Burmeister M, Greenwood TA, Hamshere ML, Muglia P, Smith EN, Zandi PP, Nievergelt CM, McKinney R, Shilling PD, Schork NJ, Bloss CS, Foroud T, Koller DL, Gershon ES, Liu C, Badner JA, Scheftner WA, Lawson WB, Nwulia EA, Hipolito M, Coryell W, Rice J, Byerley W, McMahon FJ, Schulze TG, Berrettini W, Lohoff FW, Potash JB, Mahon PB, McInnis MG, Zöllner S, Zhang P, Craig DW, Szelinger S, Barrett TB, Breuer R, Meier S, Strohmaier J, Witt SH, Tozzi F, Farmer A, McGuffin P, Strauss J, Xu W, Kennedy JL, Vincent JB, Matthews K, Day R, Ferreira MA, O'Dushlaine C, Perlis R, Raychaudhuri S, Ruderfer D, Hyoun PL, Smoller JW, Li J, Absher D, Thompson RC, Meng FG, Schatzberg AF, Bunney WE, Barchas JD, Jones EG, Watson SJ, Myers RM, Akil H, Boehnke M, Chambert K, Moran J, Scolnick E, Djurovic S, Melle I, Morken G, Gill M, Morris D, Quinn E, Mühleisen TW, Degenhardt FA, Mattheisen M, Schumacher J, Maier W, Steffens M, Propping P, Nöthen MM, Anjorin A, Bass N, Gurling H, Kandaswamy R, Lawrence J, McGhee K, McIntosh A, McLean AW, Muir WJ, Pickard BS, Breen G, St Clair D, Caesar S, Gordon-Smith K, Jones L, Fraser C, Green EK, Grozeva D, Jones IR, Kirov G, Moskvina V, Nikolov I, O'Donovan MC, Owen MJ, Collier DA, Elkin A, Williamson R, Young AH, Ferrier IN, Stefansson K, Stefansson H, Thornorgeirsson T, Steinberg S, Gustafsson O, Bergen SE, Nimgaonkar V, Hultman C, Landén M, Lichtenstein P, Sullivan P, Schalling M, Osby U, Backlund L, Frisén L, Langstrom N, Jamain S, Leboyer M, Etain B, Bellivier F, Petursson H, Sigur Sson E, Müller-Mysok B, Lucae S, Schwarz M, Schofield PR, Martin N, Montgomery GW, Lathrop M, Oskarsson H, Bauer M, Wright A, Mitchell PB, Hautzinger M, Reif A, Kelsoe JR, Purcell SM; Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 2011, 43:977-83. DOI: 10.1038/ng.943

1191 Slof-Op 't Landt MC, Meulenbelt I, Bartels M, Suchiman E, Middeldorp CM, Houwing-Duistermaat JJ, van Trier J, Onkenhout EJ, Vink JM, van Beijsterveldt CE, Brandys MK, Sanders N, Zipfel S, Herzog W, Herpertz-Dahlmann B, Klampfl K, Fleischhaker C, Zeeck A, de Zwaan M, Herpertz S, Ehrlich S, van Elburg AA, Adan RA, Scherag S, Hinney A, Hebebrand J, Boomsma DI, van Furth EF, Slagboom PE. Association study in eating disorders: TPH2 associates with anorexia nervosa and self-induced vomiting. Genes Brain Behav. 2011 Mar;10(2):236-43. doi: 10.1111/j.1601-183X.2010.00660.x. Epub 2010 Nov 22. PubMed PMID: 20946355.

1190 Soler Artigas M, Loth DW, Wain LV, Gharib SA, Obeidat M, Tang W, Zhai G, Zhao JH, Smith AV, Huffman JE, Albrecht E, Jackson CM, Evans DM, Cadby G, Fornage M, Manichaikul A, Lopez LM, Johnson T, Aldrich MC, Aspelund T, Barroso I, Campbell H, Cassano PA, Couper DJ, Eiriksdottir G, Franceschini N, Garcia M, Gieger C, Gislason GK, Grkovic I, Hammond CJ, Hancock DB, Harris TB, Ramasamy A, Heckbert SR, Heliövaara M, Homuth G, Hysi PG, James AL, Jankovic S, Joubert BR, Karrasch S, Klopp N, Koch B, Kritchevsky SB, Launer LJ, Liu Y, Loehr LR, Lohman K, Loos RJ, Lumley T, Al Balushi KA, Ang WQ, Barr RG, Beilby J, Blakey JD, Boban M, Boraska V, Brisman J, Britton JR, Brusselle GG, Cooper C, Curjuric I, Dahgam S, Deary IJ, Ebrahim S, Eijgelsheim M, Francks C, Gaysina D, Granell R, Gu X, Hankinson JL, Hardy R, Harris SE, Henderson J, Henry A, Hingorani AD, Hofman A, Holt PG, Hui J, Hunter ML, Imboden M, Jameson KA, Kerr SM, Kolcic I, Kronenberg F, Liu JZ, Marchini J, McKeever T, Morris AD, Olin AC, Porteous DJ, Postma DS, Rich SS, Ring SM, Rivadeneira F, Rochat T, Sayer AA, Sayers I, Sly PD, Smith GD, Sood A, Starr JM, Uitterlinden AG, Vonk JM, Wannamethee SG, Whincup PH, Wijmenga C, Williams OD, Wong A, Mangino M, Marciante KD, McArdle WL, Meibohm B, Morrison AC, North KE, Omenaas E, Palmer LJ, Pietiläinen KH, Pin I, Pola Sbreve Ek O, Pouta A, Psaty BM, Hartikainen AL, Rantanen T, Ripatti S, Rotter JI, Rudan I, Rudnicka AR, Schulz H, Shin SY, Spector TD, Surakka I, Vitart V, Völzke H, Wareham NJ, Warrington NM, Wichmann HE, Wild SH, Wilk JB, Wjst M, Wright AF, Zgaga L, Zemunik T, Pennell CE, Nyberg F, Kuh D, Holloway JW, Boezen HM, Lawlor DA, Morris RW, Probst-Hensch N; International Lung Cancer Consortium; GIANT consortium, Kaprio J, Wilson JF, Hayward C, Kähönen M, Heinrich J, Musk AW, Jarvis DL, Gläser S, Järvelin MR, Ch Stricker BH, Elliott P, O'Connor GT, Strachan DP, London SJ, Hall IP, Gudnason V, Tobin MD. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet 2011

1189 Soler-Lopez M, Zanzoni A, Lluis R, Stelzl U, Aloy P. Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. Genome Res. 2011 Mar;21(3):364-76.

1188 Song JY, Wang HJ, Ma J, Xu ZY, Hinney A, Hebebrand J, Wang Y. Association of the rs10830963 polymorphism in MTNR1B with fasting glucose levels in Chinese children and adolescents. Obes Facts. 2011;4(3):197-203. Epub 2011 Jun 6. PubMed PMID: 21701235.

1187 Speakman JR, Levitsky DA, Allison DB, Bray MS, de Castro JM, Clegg DJ, Clapham JC, Dulloo AG, Gruer L, Haw S, Hebebrand J, Hetherington MM, Higgs S, Jebb SA, Loos RJ, Luckman S, Luke A, Mohammed-Ali V, O'Rahilly S, Pereira M, Perusse L, Robinson TN, Rolls B, Symonds ME, Westerterp-Plantenga MS. Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity. Dis Model Mech. 2011 Nov;4(6):733-45. Review. PubMed PMID: 22065844; PubMed Central PMCID: PMC3209643.

1186 Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS; NASH CRN; GIANT Consortium; MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB; GOLD Consortium. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 2011 Mar;7(3):e1001324. Epub 2011 Mar 10.

1185 Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla LM, Lechel A, Begus-Nahrmann Y, Burkhalter MD, Mach M, Schlaudraff F, Liss B, Ju Z, Speicher MR, Rudolph KL. Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction. Nat Cell Biol. 2011 Dec 4;14(1):73-9. doi: 10.1038/ncb2388.

1184 Sperveslage J, Frank S, Heneweer C, Egberts J, Schniewind B, Buchholz M,Bergmann F, Giese N, Munding J, Hahn SA, Kalthoff H, Klöppel G, Sipos B. Lack of CCR7 expression is rate limiting for lymphatic spread of pancreatic ductaladenocarcinoma. Int J Cancer. 2011 Oct 23. doi: 10.1002/ijc.26502. [Epub ahead ofprint] PubMed PMID: 22020953.

1183 Springer W, Kahle PJ. Regulation of PINK1-Parkin-mediated mitophagy. Autophagy. 2011 Mar 1;7(3):266-78.
1182 Spyroglou A, Wagner S, Gomez-Sanchez C, Rathkolb B, Wolf E, Manolopoulou J, Reincke M, Bidlingmaier M, Hrabé de Angelis M, Beuschlein F. Utilization of a mutagenesis screen to generate mouse models of hyperaldosteronism. Endocrinology. 152(1):326-31. DOI: 10.1210/en.2010-1081

1181 Standl M, Sausenthaler S, Lattka E, Koletzko S, Bauer CP, Wichmann HE, von Berg A, Berdel D, Krämer U, Schaaf B, Lehmann I, Herbarth O, Klopp N, Koletzko B, Heinrich J; GINIplus and LISAplus Study Group. FADS gene cluster modulates the effect of breastfeeding on asthma. Results from the GINIplus and LISAplus studies. Allergy. 2011

1180 Staudinger M, Erk S, Walter H (2011). Dorsolateral prefrontal cortex modulates striatal reward encoding during reappraisal of reward anticipation. Cerebral Cortex 21(11):2578-88.

1179 Steffen B, Knop M, Bergholz U, Vakhrusheva O, Rode M, Köhler G, Henrichs MP, Bulk E, Hehn S, Stehling M, Dugas M, Bäumer N, Tschanter P, Brandts C, Koschmieder S, Berdel WE, Serve H, Stocking C, Müller-Tidow C. AML1/ETO induces self-renewal in hematopoietic progenitor cells via the Groucho-related amino-terminal AES protein. Blood. 2011 Apr 21;117(16):4328-37. Epub 2011 Jan 18.

1178 Stehr H.; Jang, S.-H.J.; Duarte, J.M.; Wierling, C.; Lehrach, H.; Lappe, M.; Lange, B.M.H. The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors. Molecular Cancer, 10:54. (2011).

1177 Steinberg S, de Jong S; Irish Schizophrenia Genomics Consortium, Andreassen OA, Werge T, Børglum AD, Mors O, Mortensen PB, Gustafsson O, Costas J, Pietiläinen OP, Demontis D, Papiol S, Huttenlocher J, Mattheisen M, Breuer R, Vassos E, Giegling I, Fraser G, Walker N, Tuulio-Henriksson A, Suvisaari J, Lönnqvist J, Paunio T, Agartz I, Melle I, Djurovic S, Strengman E; GROUP, Jürgens G, Glenthøj B, Terenius L, Hougaard DM, Ørntoft T, Wiuf C, Didriksen M, Hollegaard MV, Nordentoft M, van Winkel R, Kenis G, Abramova L, Kaleda V, Arrojo M, Sanjuán J, Arango C, Sperling S, Rossner M, Ribolsi M, Magni V, Siracusano A, Christiansen C, Kiemeney LA, Veldink J, van den Berg L, Ingason A, Muglia P, Murray R, Nöthen MM, Sigurdsson E, Petursson H, Thorsteinsdottir U, Kong A, Rubino IA, De Hert M, Réthelyi JM, Bitter I, Jönsson EG, Golimbet V, Carracedo A, Ehrenreich H, Craddock N, Owen MJ, O'Donovan MC; Wellcome Trust Case Control Consortium 2, Ruggeri M, Tosato S, Peltonen L, Ophoff RA, Collier DA, St Clair D, Rietschel M, Cichon S, Stefansson H, Rujescu D, Stefansson K. Common variants at VRK2 and TCF4 conferring risk of schizophrenia. Hum Mol Genet. 2011 Oct 15;20(20):4076-81. Epub 2011 Jul 26.

1176 Stepanow S, Reichwald, K., Huse, K., Gausmann, U., Nebel, A., Rosenstiel, P., Fischer-Posovszky. P., Wabitsch, M., Platzer, M. Allele-Specific, Age-dependent and BMI-associated DNA Methylation of Human MCHR1. PLoS One. 6(5):e17711 (2011).

1175 Stickel F, Buch S, Lau K, Meyer zu Schwabedissen H, Berg T, Ridinger M, Rietschel M, Schafmayer C, Braun F, Hinrichsen H, Günther R, Arlt A, Seeger M, Müller S, Seitz HK, Soyka M, Lerch M, Lammert F, Sarrazin C, Kubitz R, Häussinger D, Hellerbrand C, Bröring D, Schreiber S, Kiefer F, Spanagel R, Mann K, Datz C, Krawczak M, Wodarz N, Völzke H, Hampe J. Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology. 2011 Jan;53(1):86-95. doi: 10.1002/hep.24017.

1174 Strawbridge RJ., Wabitsch, M., et al. Diabetes. 60(10):2624-2634 (2011).

1173 Suffert G, Malterer G, Hausser J, Viiliäinen J, Fender A, Contrant M, Ivacevic T, Benes V, Gros F, Voinnet O, Zavolan M, Ojala PM, Haas JG, Pfeffer S. Kaposi's sarcoma herpesvirus microRNAs target caspase 3 and regulate apoptosis. PLoS Pathog. 2011 Dec;7(12):e1002405. Epub 2011 Dec 8.

1172 Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E; CARDIoGRAM, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C. Human metabolic individuality in biomedical and pharmaceutical research. Nature. 2011 Aug 31;477(7362):54-60. doi: 10.1038/nature10354.

1171 Suhre K, Wallaschofski H, Raffler J, Friedrich N, Haring R, Michael K, Wasner C, Krebs A, Kronenberg F, Chang D, Meisinger C, Wichmann HE, Hoffmann W, Völzke H, Völker U, Teumer A, Biffar R, Kocher T, Felix SB, Illig T, Kroemer HK, Gieger C, Römisch-Margl W, Nauck M. A genome-wide association study of metabolic traits in human urine. Nat Genet 2011

1170 Suk E-K, McEwen GK, Duitama J, Nowick K, Schulz S, Palczewski S, Schreiber S, Holloway DT, McLaughlin S, Peckham H, Lee C, Huebsch T, and Hoehe MR. A Comprehensively Molecular Haplotype-Resolved Genome of a European Individual. Genome Res 2011 Oct;21(10):1672-85. Epub 2011 Aug 3.

1169 Sun LD, Xiao FL, Li Y, Zhou WM, Tang HY, Tang XF, Zhang H, Schaarschmidt H, Zuo XB, Foelster-Holst R, He SM, Shi M, Liu Q, Lv YM, Chen XL, Zhu KJ, Guo YF, Hu DY, Li M, Li M, Zhang YH, Zhang X, Tang JP, Guo BR, WangH, Liu Y, Zou XY, Zhou FS, Liu XY, Chen G, Ma L, Zhang SM, Jiang AP, Zheng XD, Gao XH, Li P, Tu CX, Yin XY, Han XP, Ren YQ, Song SP, Lu ZY, Zhang XL, Cui Y, Chang J, Gao M, Luo XY, Wang PG, Dai X, Su W, Li H, ShenCP, Liu SX, Feng XB, Yang CJ, Lin GS, Wang ZX, Huang JQ, Fan X, Wang Y, Bao YX, Yang S, Liu JJ, Franke A, Weidinger S, Yao ZR, Zhang XJ. Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population. Nat Genet 2011; 43:690-4

1168 Surakka I, Isaacs A, Karssen LC, Laurila PP, Middelberg RP, Tikkanen E, Ried JS, Lamina C, Mangino M, Igl W, Hottenga JJ, Lagou V, van der Harst P, Mateo Leach I, Esko T, Kutalik Z, Wainwright NW, Struchalin MV, Sarin AP, Kangas AJ, Viikari JS, Perola M, Rantanen T, Petersen AK, Soininen P, Johansson A, Soranzo N, Heath AC, Papamarkou T, Prokopenko I, Tönjes A, Kronenberg F, Döring A, Rivadeneira F, Montgomery GW, Whitfield JB, Kähönen M, Lehtimäki T, Freimer NB, Willemsen G, de Geus EJ, Palotie A, Sandhu MS, Waterworth DM, Metspalu A, Stumvoll M, Uitterlinden AG, Jula A, Navis G, Wijmenga C, Wolffenbuttel BH, Taskinen MR, Ala-Korpela M, Kaprio J, Kyvik KO, Boomsma DI, Pedersen NL, Gyllensten U, Wilson JF, Rudan I, Campbell H, Pramstaller PP, Spector TD, Witteman JC, Eriksson JG, Salomaa V, Oostra BA, Raitakari OT, Wichmann HE, Gieger C, Järvelin MR, Martin NG, Hofman A, McCarthy MI, Peltonen L, van Duijn CM, Aulchenko YS, Ripatti S; ENGAGE Consortium. A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genetics 2011

1167 Svendsen A, Verhoeff JJ, Immervoll H, Brøgger JC, Kmiecik J, Poli A, Netland IA, Prestegarden L, Planagumà J, Torsvik A, Kjersem AB, Sakariassen PO, Heggdal JI, Van Furth WR, Bjerkvig R, Lund-Johansen M, Enger PO, Felsberg J, Brons NH, Tronstad KJ, Waha A, Chekenya M. Expression of the progenitor marker NG2/CSPG4 predicts poor survival and resistance to ionising radiation in glioblastoma. Acta Neuropathol. Oct;122(4):495-510.

1166 Taudien S, Szafranski K, Felder M, Groth M, Huse K, Raffaelli F, Petzold A, Zhang X, Rosenstiel P, Hampe J, Schreiber S, Platzer M. Comprehensive assessment of sequence variation within the copy number variable defensin cluster on 8p23 by target enriched in-depth 454 sequencing. BMC Genomics. 2011 May 18;12(1):243.

1165 Taylor, A.M., Niewoehner, B., Seeburg, P.H., Sprengel, R., Rawlins, J.N.P., Bannerman, D.M., and Sanderson, D.J. (2011). Dissociations within short-term memory in GluA1 AMPA receptor subunit knockout mice. Behav Brain Res 224, 8?14.

1164 Teichler S, Illmer T, Roemhild J, Ovcharenko D, Stiewe T, Neubauer A. MicroRNA29a regulates the expression of the nuclear oncogene Ski. Blood. 2011 Aug; 118(7):1899-1902

1163 Tesse R, Pandey RC, Kabesch M. Genetic variations in toll-like receptor pathway genes influence asthma and atopy. Allergy. 2011 Mar;66(3):307-16. doi: 10.1111/j.1398-9995.2010.02489.x. Epub 2010 Oct 8.

1162 Tesse R, Schieck M, Kabesch M. Asthma and endocrine disorders: shared mechanisms and genetic pleiotropy. Mol Cell Endocrinol. 2011 Feb 20;333(2):103-11. Epub 2010 Dec 4.

1161 Teumer A, Rawal R, Homuth G, Ernst F, Heier M, Evert M, Dombrowski F, Völker U, Nauck M, Radke D, Ittermann T, Biffar R, Döring A, Gieger C, Klopp N, Wichmann HE, Wallaschofski H, Meisinger C, Völzke H. Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk. Am. J. Hum. Genet. 2011

1160 Tews D, Fischer-Posovszky P, Wabitsch M. Regulation of FTO and FTM expression during human preadipocyte differentiation. Horm Metab Res 2011 Jan;43(1):17-21

1159 Thalappilly S, Feng X, Pastyryeva S, Suzuki K, Muruve D, Larocque D, Richard S, Truss M, von Deimling A, Riabowol K, Tallen G. The p53 tumor suppressor is stabilized by inhibitor of growth 1 (ING1) by blocking polyubiquitination. PLoS One. 2011;6(6):e21065 doi 10.1371/journal.pone.0021065

1158 Theis M, Buchholz F. High-throughput RNAi screening in mammalian cells with esiRNAs. Methods. Apr;53(4):424-9.

1157 Thier S, Kuhlenbäumer G, Lorenz D, Nothnagel M, Nebel A, Christensen K, Schreiber S, Deuschl G, Klebe S (2011). GABA(A) receptor- and GABA transporter polymorphisms and risk for essential tremor. Eur J Neurol, 18(8):1098-100.

1156 Thoeringer CK, Henes K, Eder M, Dahlhoff M, Wurst W, Holsboer F, Deussing JM, Moosmang S, Wotjak CT. Consolidation of Remote Fear Memories Involves Corticotropin-Releasing Hormone (CRH) Receptor Type 1-Mediated Enhancement of AMPA Receptor GluR1 Signaling in the Dentate Gyrus. Neuropsychopharmacology. 2011 Oct 26. doi: 10.1038/npp.2011.256. [Epub ahead of print]

1155 Thomas-Chollier M, Hufton A, Heinig M, O'Keeffe S, Masri NE, Roider HG, Manke T, Vingron M. Transcription factor binding predictions using TRAP for the analysis of ChIP-seq data and regulatory SNPs. Nat Protoc. 2011 Nov 3;6(12):1860-9. doi: 10.1038/nprot.2011.409. PubMed PMID: 22051799.

1154 Tickenbrock L, Klein HU, Trento C, Hascher A, Göllner S, Bäumer N, Kuss R, Agrawal S, Bug G, Serve H, Thiede C, Ehninger G, Stadt UZ, McClelland M, Wang Y, Becker A, Koschmieder S, Berdel WE, Dugas M, Müller-Tidow C; for the SAL (Study Alliance Leukemia) Group. Increased HDAC1 deposition at hematopoietic promoters in AML and its association with patient survival. Leuk Res. 2011 May;35(5):620-5. Epub 2010 Dec 22.

1153 Toedt G, Barbus S, Wolter M, Felsberg J, Tews B, Blond F, Sabel MC, Hofmann S, Becker N, Hartmann C, Ohgaki H, von Deimling A, Wiestler OD, Hahn M, Lichter P, Reifenberger G, Radlwimmer B. Molecular signatures classify astrocytic gliomas by IDH1 mutation status. Int J Cancer. 2011 Mar 1;128(5):1095-103. doi: 10.1002/ijc.25448.

1152 Tolosi L, Lengauer T. Classification with correlated features: unreliability of feature ranking and solutions. Bioinformatics. 2011 Jul 15;27(14):1986-94. Epub 2011 May 16.

1151 Torres Salazar, A., Hoheisel, J.D., Youns, M. & Wink, M. Anti-inflammatory and anti-cancer activities of essential oils and their biological constituents. Int. J. Clin. Pharmacol. Ther. 49, 93-95 (2011).

1150 Tozzi A, Costa C, Siliquini S, Tantucci M, Picconi B, Kurz A, Gispert S, Auburger G, Calabresi P. Mechanisms underlying altered striatal synaptic plasticity in old A53T-? synuclein overexpressing mice. Neurobiol Aging. 2011 Jun 16. [Epub ahead of print]

1149 Trebicka J, Racz I, Siegmund SV, Cara E, Granzow M, Schierwagen R, Klein S, Wojtalla A, Hennenberg M, Huss S, Fischer HP, Heller J, Zimmer A, Sauerbruch T. Role of cannabinoid receptors in alcoholic hepatic injury: steatosis and fibrogenesis are increased in CB(2) receptor-deficient mice and decreased in CB(1) receptor knockouts. Liver Int. 2011 Jul;31(6):862-72.

1148 Treutlein J, Rietschel M. Genome-wide association studies of alcohol dependence and substance use disorders. Curr Psychiatry Rep. 2011 Apr;13(2):147-55.

1147 Tückmantel, S., J.N. Greul, P. Janning, A. Brockmeyer, C. Grütter, J.R. Simard, O. Gutbrod, M.E. Beck, K. Tietjen, D. Rauh, P.H. Schreier. Identification of Ustilago maydis Aurora Kinase As a Novel Antifungal Target. ACS Chem Biol, 2011, 6(9):926-33.

1146 Tyshchenko N, Neuhann TM, Gerlach E, Hahn G, Heisch K, Rump A, Schrock E, Tinschert S, Hackmann K. A new autosomal dominant syndrome of distinctive face showing ptosis and prominent eyes associated with cleft palate, ear anomalies, and learning disability. Am J Med Genet A. 2011 Sep;155A(9):2060-5. PMID:21834043

1145 Ummanni R, Jost E, Braig M, Lohmann F, Mundt F, Barett C, Schlomm T, Sauter G, Senff T, Bokemeyer C, Sültmann H, Meyer-Schwesinger C, Brümmendorf TH, Balabanov S. Ubiquitin carboxyl-terminal hydrolase 1 (UCHL1) is a potential tumour suppressor in prostate cancer and is frequently silenced by promoter methylation. Mol Cancer. 2011;10:129

1144 Ummanni R, Mundt F, Pospisil H, Venz S, Barett C, Fälth M, Köllermann J, Walther R, Schlomm T, Sauter G, Bokemeyer C, Sültmann H, Schuppert A, Brümmendorf TH, Balabanov S. Identification of clinically relevant protein targets in prostate cancer with 2D-DIGE coupled mass spectrometry and systems biology network platform. PLOS One 2011 Feb 11;6(2):e16833

1143 Unal-Cevik I, Gursoy-Ozdemir Y, Yemisci M, Lule S, Gurer G, Can A, Müller V, Kahle PJ, Dalkara T. Alpha-synuclein aggregation induced by brief ischemia negatively impacts neuronal survival in vivo: a study in [A30P]alpha-synuclein transgenic mouse. J Cereb Blood Flow Metab. 2011 Mar;31(3):913-23.

1142 Valen E., Preker P., Andersen P.R., Zhao X., Chen Y., Ender C., Dueck A., Meister G., Sandelin A. & Jensen T.H. Biogenic mechanisms and utilization of small RNAs from human protein-coding genes. Nat. Struct. Mol. Biol., 18(9):1075-82.

1141 Van Maerken T, Rihani A, Dreidax D, De Clercq S, Yigit N, Marine JC,Westermann F, De Paepe A, Vandesompele J, Speleman F. Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonistnutlin-3. Mol Cancer Ther. 2011 Apr 1. [Epub ahead of print]

1140 Van Schijndel JE, Van Zweeden M, Van Loo KM, Djurovic S, Andreassen OA, Hansen T, Werge T, Nyegaard M, Sørensen KM, Nordentoft M, Mortensen PB, Mors O, Børglum AD, Del-Favero J, Norrback KF, Adolfsson R, Hert MD, Claes S, Cichon S, Rietschel M, Nöthen MM, Kallunki P, Pedersen JT, Martens GJ. Dual association of a TRKA polymorphism with schizophrenia. Psychiatr Genet. 2011 Feb 10. [Epub ahead of print]

1139 Vansteenkiste J, Solomon B, Boyer M, Wolf J, Miller N, Di Scala L, Pylvaenaeinen I, Petrovic K, Dimitrijevic S, Anrys B, Laack E. Everolimus in Combination with Pemetrexed in Patients with Advanced Non-small Cell Lung Cancer Previously Treated with Chemotherapy: A Phase I Study Using a Novel, Adaptive Bayesian Dose-Escalation Model. J Thorac Oncol. 2011 Dec;6(12):2120-9.

1138 Villard E, Perret C, Gary F, Proust C, Dilanian G, Hengstenberg C, Ruppert V, Arbustini E, Wichter T, Germain M, Dubourg O, Tavazzi L, Aumont MC, Degroote P, Fauchier L, Trochu JN, Gibelin P, Aupetit JF, Stark K, Erdmann J,Hetzer R, Roberts AM, Barton PJ, Regitz-Zagrosek V; Cardiogenics Consortium, Aslam U, Duboscq-Bidot L, Meyborg M, Maisch B, Madeira H, Waldenström A, Galve E, Cleland JG, Dorent R, Roizes G, Zeller T, Blankenberg S, Goodall AH, Cook S, Tregouet DA, Tiret L, Isnard R, Komajda M, Charron P, Cambien F. A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. Eur Heart J. 2011 Apr 1.

1137 Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE. A directed protein interaction network for investigating intracellular signal transduction. Sci Signal. 2011 Sep 6;4(189):rs8.

1136 Vintonyak, V.V., H. Waldmann, D. Rauh. Using small molecules to target protein phosphatases. Bioorg Med Chem, 2011, 19(7):2145-55.

1135 Vintonyak, V.V., K. Warburg, B. Over, K. Hübel, D. Rauh, H. Waldmann. Identification and further development of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B. Tetrahedron, 2011, 67(35):6713-29.

1134 Vogel CI, Boes T, Reinehr T, Roth CL, Scherag S, Scherag A, Hebebrand J, Hinney A. Common variants near MC4R: exploring gender effects in overweight and obese children and adolescents participating in a lifestyle intervention. Obes Facts. 2011;4(1):67-75. Epub 2011 Feb 22.

1133 Vollstädt-Klein S,  Löber S, Kirsch M, Bach P, Richter A,  Bühler M, von der Goltz C, Hermann D, Mann K, Kiefer F. Effects of cue-exposure treatment on neutral cue reactivity in alcohol-dependence: a randomized trial. Biological Psychiatry, 2011, 69, 1060-1066.

1132 Vollstädt-Klein S, Löber S, Richter A, Kirsch M, Bach P, von der Goltz C, Hermann D, Mann K, Kiefer F. Validating incentive salience with fMRI: association between mesolimbic cue-reactivity and attentional bias in alcohol-dependent patients. Addiction Biology, published online July 2011 (doi: 10.111/j.1369-1600.2011.00352.x).

1131 von Bubnoff N, Gorantla SP, Engh RA, Oliveira TM, Thöne S, Aberg E, Peschel C, Duyster J. The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro. Oncogene. 2011 Feb 24;30(8):933-43. Epub 2010 Oct 25.

1130 von Wolff G, Avrabos C, Stepan J, Wurst W, Deussing JM, Holsboer F, Eder M. Voltage-sensitive dye imaging demonstrates an enhancing effect of corticotropin-releasing hormone on neuronal activity propagation through the hippocampal formation. J Psychiatr Res. 2011 Feb;45(2):256-61.

1129 Waha A, Felsberg J, Hartmann W, Hammes J, von dem Knesebeck A, Endl E, Pietsch T, Waha A. Frequent epigenetic inactivation of the chaperone SGNE1/7B2 in human gliomas. Int. J. Cancer (2011) Sep 7. doi: 10.1002/ijc.26416. [Epub ahead of print]

1128 Wain LV, Verwoert GC, O'Reilly PF, Shi G, Johnson T, Johnson AD, Bochud M, Rice KM, Henneman P, Smith AV, Ehret GB, Amin N, Larson MG, Mooser V, Hadley D, Dörr M, Bis JC, Aspelund T, Esko T, Janssens AC, Zhao JH, Heath S, Laan M, Fu J, Pistis G, Luan J, Arora P, Lucas G, Pirastu N, Pichler I, Jackson AU, Webster RJ, Zhang F, Peden JF, Schmidt H, Tanaka T, Campbell H, Igl W, Milaneschi Y, Hottenga JJ, Vitart V, Chasman DI, Trompet S, Bragg-Gresham JL, Alizadeh BZ, Chambers JC, Guo X, Lehtimäki T, Kühnel B, Lopez LM, Polašek O, Boban M, Nelson CP, Morrison AC, Pihur V, Ganesh SK, Hofman A, Kundu S, Mattace-Raso FU, Rivadeneira F, Sijbrands EJ, Uitterlinden AG, Hwang SJ, Vasan RS, Wang TJ, Bergmann S, Vollenweider P, Waeber G, Laitinen J, Pouta A, Zitting P, McArdle WL, Kroemer HK, Völker U, Völzke H, Glazer NL, Taylor KD, Harris TB, Alavere H, Haller T, Keis A, Tammesoo ML, Aulchenko Y, Barroso I, Khaw KT, Galan P, Hercberg S, Lathrop M, Eyheramendy S, Org E, Sõber S, Lu X, Nolte IM, Penninx BW, Corre T, Masciullo C, Sala C, Groop L, Voight BF, Melander O, O'Donnell CJ, Salomaa V, d'Adamo AP, Fabretto A, Faletra F, Ulivi S, Del Greco M F, Facheris M, Collins FS, Bergman RN, Beilby JP, Hung J, Musk AW, Mangino M, Shin SY, Soranzo N, Watkins H, Goel A, Hamsten A, Gider P, Loitfelder M, Zeginigg M, Hernandez D, Najjar SS, Navarro P, Wild SH, Corsi AM, Singleton A, de Geus EJ, Willemsen G, Parker AN, Rose LM, Buckley B, Stott D, Orru M, Uda M, van der Klauw MM, Zhang W, Li X, Scott J, Chen YD, Burke GL, Kähönen M, Viikari J, Döring A, Meitinger T, Davies G, Starr JM, Emilsson V, Plump A, Lindeman JH, Hoen PA, König IR, Felix JF, Clarke R, Hopewell JC, Ongen H, Breteler M, Debette S, Destefano AL, Fornage M, Mitchell GF, Smith NL, Holm H, Stefansson K, Thorleifsson G, Thorsteinsdottir U, Samani NJ, Preuss M, Rudan I, Hayward C, Deary IJ, Wichmann HE, Raitakari OT, Palmas W, Kooner JS, Stolk RP, Jukema JW, Wright AF, Boomsma DI, Bandinelli S, Gyllensten UB, Wilson JF, Ferrucci L, Schmidt R, Farrall M, Spector TD, Palmer LJ, Tuomilehto J, Pfeufer A, Gasparini P, Siscovick D, Altshuler D, Loos RJ, Toniolo D, Snieder H, Gieger C, Meneton P, Wareham NJ, Oostra BA, Metspalu A, Launer L, Rettig R, Strachan DP, Beckmann JS, Witteman JC, Erdmann J, van Dijk KW, Boerwinkle E, Boehnke M, Ridker PM, Jarvelin MR, Chakravarti A, Abecasis GR, Gudnason V, Newton-Cheh C, Levy D, Munroe PB, Psaty BM, Caulfield MJ, Rao DC, Tobin MD, Elliott P, van Duijn CM; LifeLines Cohort Study; EchoGen consortium; AortaGen Consortium; CHARGE Consortium Heart Failure Working Group; KidneyGen consortium; CKDGen consortium; Cardiogenics consortium; CardioGram. Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet 2011

1127 Walter H, Schnell K, Erk S, Arnold C, Kirsch P, Esslinger C, Mier D, Schmitgen MM, Rietschel M, Witt SH, Nöthen MM, Cichon S, Meyer-Lindenberg A. Effects of a genome-wide supported psychosis risk variant on neural activation during a theory-of-mind task. Molecular Psychiatry. 2011 Apr;16(4):462-70 doi:10.1038/mp.2010.18

1126 Walter H, Schnell K, Erk S, Arnold C, Kirsch P, Esslinger C, Mier D, Schmitgen MM, Rietschel M, Witt SH, Nöthen MM, Cichon S, Meyer-Lindenberg A. Genetic risk for schizophrenia impacts Theory-of-Mind-related brain activation. Molecular Psychiatry 16:353. doi:10.1038/mp.2011.25

1125 Wan F, Herold-Mende C, Campos B, Centner FS, Dictus C, Becker N, Devens F, Mogler C, Felsberg J, Grabe N, Reifenberger G, Lichter P, Unterberg A, Bermejo JL, Ahmadi R. Association of stem cell-related markers and survival in astrocytic gliomas. Biomarkers. 2011 Mar;16(2):136-43.

1124 Wang XD, Chen Y, Wolf M, Wagner KV, Liebl C, Scharf SH, Harbich D, Mayer B, Wurst W, Holsboer F, Deussing JM, Baram TZ, Müller MB, Schmidt MV. Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodeling. Neurobiol Dis. 2011 Jun;42(3):300-10. Epub 2011 Feb 3.

1123 Wang XD, Chen Y, Wolf M, Wagner KV, Liebl C, Scharf SH, Harbich D, Mayer B, Wurst W, Holsboer F, Deussing JM, Baram TZ, Müller MB, Schmidt MV. Forebrain CRHR1 deficiency attenuates chronic stress-induced cognitive deficits and dendritic remodelling. Neurobiol Dis. 2011 Jun;42(3):300-10. Epub 2011 Feb 3.

1122 Wang XD, Rammes G, Kraev I, Wolf M, Liebl C, Scharf SH, Rice CJ, Wurst W, Holsboer F, Deussing JM, Baram TZ, Stewart MG, Müller MB, Schmidt MV. Forebrain CRF? modulates early-life stress-programmed cognitive deficits. J Neurosci. 2011 Sep 21;31(38):13625-34.

1121 Wang XD, Rammes G, Kraev I, Wolf M, Liebl C, Scharf SH, Rice CJ, Wurst W, Holsboer F, Deussing JM, Baram TZ, Stewart MG, Müller MB, Schmidt MV. Forebrain CRF1 modulates early-life stress-programmed cognitive deficits. J Neurosci. 2011 Sep 21;31(38):13625-34.

1120 Weber YG, Kamm C, Suls A, Kempfle J, Kotschet K, Wuttke TV, Schuele-Freyer R, Maljevic S, Liebrich J, Gasser T, Ludolph AC, van Paesschen W, Schoels L, De Jonghe P, Auburger G, Lerche H. Paroxysmal choreoathetosis/spasticity (DYT9) is caused by a GLUT1 defect. "Neurology 2011;77:959-64."

1119 Wellge BE, Sterneck M, Teufel A, Rust C, Franke A, Schreiber S, Berg T,Günther R, Kreisel W, Zu Eulenburg C, Braun F, Beuers U, Galle PR, Lohse AW, Schramm C. Pregnancy in primary sclerosing cholangitis. Gut. 2011 Feb 21. [Epub ahead of print] PubMed PMID: 21339205

1118 Welsch T, Zschäbitz S, Becker V, Giese T, Bergmann F, Hinz U, Keleg S, Heller A, Sipos B, Klingmüller U, Büchler MW, Werner J, Giese NA. Prognostic significance of erythropoietin in pancreatic adenocarcinoma. PLoS One. 2011;6(8):e23151. Epub 2011 Aug 1.

1117 Weyer SA, Klevanski M, Delekate A, Voikar V, Aydin D, Hick M, Filippov MA, Drost N, Schaller KL, Saar M, Vogt MA, Gass P, Samanta A, Jäschke A, Korte M, Wolfer DP, Caldwell JH, Müller UC. APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP. EMBO J, 30:2266.

1116 Wichmann HE, Kuhn KA, Waldenberger M, Schmelcher D, Schuffenhauer S, Meitinger T, Wurst SH, Lamla G, Fortier I, Burton PR, Peltonen L, Perola M, Metspalu A, Riegman P, Landegren U, Taussig MJ, Litton JE, Fransson MN, Eder J, Cambon-Thomsen A, Bovenberg J, Dagher G, van Ommen GJ, Griffith M, Yuille M, Zatloukal K. Comprehensive catalog of European biobanks. Nat Biotechnol. 2011

1115 Wiedon A, Tölle M, Bastine J, Schuchardt M, Huang T, Jankowski V, Jankowski J, Zidek W, van der Giet M. Uridine adenosine tetraphosphate (Up4A) is a strong inductor of smooth muscle cell migration via activation of the P2Y2 receptor and cross-communication to the PDGF receptor. Biochem Biophys Res Commun. 2012 Jan 20;417(3):1035-40. Epub 2011 Dec 26.

1114 Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB, Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann H, Diemert P, Cupples LA, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE, Voight BF, Kuulasmaa K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB, Demissie S, Proust C, König IR, Wichmann HE, Reinhard W, Hoffmann MM, Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu L, El Mokthari NE, Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JC, Uitterlinden AG, Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A, Blankenberg S. A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011 Aug 1; 4(4):403-12. Epub 2011 May 23

1113 Willour VL, Seifuddin F, Mahon PB, Jancic D, Pirooznia M, Steele J, Schweizer B, Goes FS, Mondimore FM, Mackinnon DF; The Bipolar Genome Study (BiGS) Consortium, Perlis RH, Lee PH, Huang J, Kelsoe JR, Shilling PD, Rietschel M, Nöthen M, Cichon S, Gurling H, Purcell S, Smoller JW, Craddock N, Depaulo JR Jr, Schulze TG, McMahon FJ, Zandi PP, Potash JB. A genome-wide association study of attempted suicide. Mol Psychiatry. 2011 Mar 22. [Epub ahead of print]

1112 Winkelmann J, Czamara D, Schormair B, Knauf F, Schulte EC, Trenkwalder C, Dauvilliers Y, Polo O, Högl B, Berger K, Fuhs A, Gross N, Stiasny-Kolster K, Oertel W, Bachmann CG, Paulus W, Xiong L, Montplaisir J, Rouleau GA, Fietze I, Vávrová J, Kemlink D, Sonka K, Nevsimalova S, Lin SC, Wszolek Z, Vilariño-Güell C, Farrer MJ, Gschliesser V, Frauscher B, Falkenstetter T, Poewe W, Allen RP, Earley CJ, Ondo WG, Le WD, Spieler D, Kaffe M, Zimprich A, Kettunen J, Perola M, Silander K, Cournu-Rebeix I, Francavilla M, Fontenille C, Fontaine B, Vodicka P, Prokisch H, Lichtner P, Peppard P, Faraco J, Mignot E, Gieger C, Illig T, Wichmann HE, Müller-Myhsok B, Meitinger T. Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. PLoS Genetics. 2011

1111 Winter Y, Back T, Scherag A, Linseisen J, Rohrmann S, Lanczik O, Hinney A,Scherag S, Neumaier M, Ringleb PA, Dodel R, Hebebrand J. Evaluation of the obesity genes FTO and MC4R and the type 2 diabetes mellitus gene TCF7L2 for contribution to stroke risk: The Mannheim-Heidelberg Stroke Study. Obes Facts. 2011;4(4):290-6. Epub 2011 Aug 1. PubMed PMID: 21921652.

1110 Wirth EK, Sheu SY, Chiu-Ugalde J, Sapin R, Klein MO, Moßbrugger I, Quintanilla-Martinez L, Hrabé de Angelis M, Krude H, Riebel T, Rothe K, Köhrle J, Schmid KW, Schweizer U, Grüters A. Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy. Eur J Endocrinol. 165(4):555-61. DOI: 10.1530/EJE-11-0369

1109 Wittig-Blaich SM, Kacprzyk LA, Eismann T, Bewerunge-Hudler M, Kruse P, Winkler E, Strauss WS, Hibst R, Steiner R, Schrader M, Mertens D, Sültmann H, Wittig R. Matrix-dependent regulation of AKT in Hepsin-overexpressing PC3 prostate cancer cells. Neoplasia, 2011, 13(7):579-89

1108 Wittkop T, Emig D, Truss A, Albrecht M, Böcker S, Baumbach J. Comprehensive cluster analysis with Transitivity Clustering. Nat Protoc. 2011 Feb;6(3):285-95.

1107 Wohlleber E*, Kirchhoff M*, Zink AM*, Kreiß-Nachtsheim M, Küchler A, Jepsen B, Kjaergaard S, Engels H (2011). Clinical and molecular characterization of two patients with overlapping de novo microdeletions in 2p14-p15 and mild mental retardation. European Journal of Medical Genetics 54 67-72

1106 Wolff C, Malinowsky K, Berg D, Schragner K, Schuster T, Walch A, Bronger H,Höfler H, Becker KF. Signalling networks associated with urokinase-typeplasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: new insights from protein microarray analysis. J Pathol. 2011 Jan;223(1):54-63.

1105 Wolff C, Schott C, Porschewski P, Reischauer B, Becker KF. Successful protein extraction from over-fixed and long-term stored formalin-fixed tissues. PLoS One. 2011 Jan 31;6(1):e16353

1104 Wrzodek A, Dräger A, and Zell A. KEGGtranslator: visualizing and converting the KEGG PATHWAY database to various formats. Bioinformatics, 27(16):2314-2315, June 2011. doi:10.1093/bioinformatics/btr377

1103 Youns, M., Bauer, A., Reichling, J., Fellenberg, K., Efferth, T. & Hoheisel, J.D. Gene expression profiling identifies novel key players involved in chemopreventive effect of NS-398 on pancreatic cancer cells. Eur. J. Pharmacol. 650, 170-177 (2011).

1102 Yu Z, Kastenmüller G, He Y, Belcredi P, Möller G, Prehn C, Mendes J, Wahl S,Roemisch-Margl W, Ceglarek U, Polonikov A, Dahmen N, Prokisch H, Xie L, Li Y,Wichmann HE, Peters A, Kronenberg F, Suhre K, Adamski J, Illig T, Wang-Sattler R. Differences between human plasma and serum metabolite profiles. PLoS One. 2011;6(7):e21230. Epub 2011 Jul 8

1101 Zander T, Hofmann A, Staratschek-Jox A, Classen S, Debey-Pascher S, Maisel D, Ansén S, Hahn M, Beyer M, Thomas RK, Gathof B, Mauch C, Delank KS, Engel-Riedel W, Wichmann HE, Stoelben E, Schultze JL, Wolf J. Blood-based gene expression signatures in non-small cell lung cancer. Clin Cancer Res. 2011 May 15;17(10):3360-7. Epub 2011 May 10

1100 Zander T, Scheffler M, Nogova L, Kobe C, Engel-Riedel W, Hellmich M, Papachristou I, Toepelt K, Draube A, Heukamp L, Buettner R, Ko YD, Ullrich RT, Smit E, Boellaard R, Lammertsma AA, Hallek M, Jacobs AH, Schlesinger A, Schulte K, Querings S, Stoelben E, Neumaier B, Thomas RK, Dietlein M, Wolf J Early Prediction of Nonprogression in Advanced Non-Small-Cell Lung Cancer Treated With Erlotinib By Using [18F]Fluorodeoxyglucose and [18F]Fluorothymidine Positron Emission Tomography. J Clin Oncol. 2011 Mar 21. [Epub ahead of print]

1099 Zeller T, Blankenberg S, Diemert P. Genomewide association studies in cardiovascular disease--an update 2011. Clin Chem. 2012 Jan;58(1):92-103. Epub 2011 Nov 28. Review.

1098  Zhang JD, Koerner C, Bechtel S, Bender C, Keklikoglou I, Schmidt C, Irsigler A, Ernst U, Sahin O, Wiemann S, Tschulena U (2011) Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PLoS ONE 6: e22176.

1097  Zimprich A, Benet-Pagès A, Struhal W, Graf E, Eck SH, Offman MN, Haubenberger D, Spielberger S, Schulte EC, Lichtner P, Rossle SC, Klopp N, Wolf E, Seppi K, Pirker W, Presslauer S, Mollenhauer B, Katzenschlager R, Foki T, Hotzy C, Reinthaler E, Harutyunyan A, Kralovics R, Peters A, Zimprich F, Brücke T, Poewe W, Auff E, Trenkwalder C, Rost B, Ransmayr G, Winkelmann J, Meitinger T, Strom TM. A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am J Hum Genet. 2011 Jul 15;89(1):168-75. PubMed PMID: 21763483; PubMed Central PMCID: PMC3135812.

1096  Zink M, Ferbert T, Frank ST, Seufert P, Gebicke-Haerter PJ, Spanagel R (2011). Perinatal exposure to alcohol disturbs spatial learning and glutamate transmission-related gene expression in the adult hippocampus. Eur J Neurosci. 34:457-68

1095   Zittel S, Kroeger J, van der Vegt JP, Siebner HR, Brüggemann N, Ramirez A, Behrens MI, Gerloff C, Bäumer T, Klein C, Münchau A. Motor pathway excitability in ATP13A2 mutation carriers: A transcranial magnetic stimulation study. Parkinsonism Relat Disord 2011.

1094   Zürner M, Mittelstaedt T, tom Dieck S, Becker A, Schoch S. Analyses of the spatiotemporal expression and subcellular localization of liprin-? proteins.J Comp Neurol. 2011 Oct 15;519(15):3019-39. doi: 10.1002/cne.22664. PMID: 21618221

2010

1093    Abou Jamra R, Schulze TG, Becker T, Brockschmidt FF, Green E, Alblas MA, Wendland JR, Adli M, Grozeva D, Strohmeier J, Georgi A, Craddock N, Propping P, Rietschel M, Nöthen MM, Cichon S, Schumacher J. A systematic association mapping on chromosome 6q in bipolar affective disorder-evidence for the melanin-concentrating-hormone-receptor-2 gene as a risk factor for bipolar affective disorder. American Journal of Medical Genetics 153B:878-884. DOI: 10.1002/ajmg.b.31051

1092    Abraham NM, Egger V, Shimshek DR, Renden R, Fukunaga I, Sprengel R, Seeburg PH, Klugmann M, Margrie TW, Schaefer AT, Kuner T. Synaptic inhibition in the olfactory bulb accelerates odor discrimination in mice. Neuron. 2010 Feb 11;65(3):399-411.

1091    Abu-Qatouseh LF, Chinni SV, Seggewiß J, Proctor RA, Brosius J, Rozhdestvensky TS, Peters G, von Eiff C, Becker K. Identification of differentially expressed small non-protein-coding RNAs in Staphylococcus aureus displaying both the normal and the small-colony variant phenotype. J Mol Med. 2010 Feb 12. [Epub ahead of print].

1090    Adler H. Comment on: Induction of TGF-beta1, not regulatory T cells, impairs antiviral immunity in the lung following bone marrow transplant. (J. of Immunology, 185 (2010): 1350-1351).

1089    Aguilar-Pimentel JA, Alessandrini F, Huster KM, Jakob T, Schulz H, Behrendt H, Ring J, Hrab? de Angelis M, Busch DH, Mempel M, Ollert M. Specific CD8 T cells in IgE-mediated allergy correlate with allergen dose and allergic phenotype. Am J Resp Crit Care Med 181:7-16. DOI: 10.1164/rccm.200902-0190OC

1088    Akil I, Ozguven A, Canda E, Yilmaz O, Nese N, Ozkol M, May S, Franke A, Cirak S. Co-existence of chronic renal failure, renal clear cell carcinoma, and Blau syndrome. Pediatr Nephrol 2010;25:977-81.

1087    Albayrak O, Tirniceriu A, Riemenschneider M, Kurz A, Scherag A, Egensperger R. The cathepsin D (224C/T) polymorphism confers an increased risk to develop Alzheime´s disease in men. J Gerontol A Biol Sci Med Sci. 2010;65(3):219-24. [Epub ahead of print]

1086    Alberts, R., Srivastava, B., Wu, H., Viegas, N., Geffers, R., Klawonn, F., Novoselova, N., Zaverucha do Valle, T., Panthier, J. J., and Schughart, K. Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection. Microbes Infect. 2010 April;12(4):309-18 doi:10.1016/j.micinf.2010.01.008

1085    Albrecht M, Sharma CM, Reinhardt R, Vogel J, Rudel T. Deep sequencing-based discovery of the Chlamydia trachomatis transcriptome.Nucleic Acids Res. 2010 Jan;38(3):868-77.

1084    Alhamdani, M.S., Schröder, C. & Hoheisel, J.D. Analysis conditions for proteomic profiling of mammalian tissue and cell extracts with antibody microarrays. Proteomics 10, 3203-3207.

1083    Alhamdani, M.S.S., Schröder, C., Giese, N., Bauer, A. & Hoheisel, J.D. Single-step procedure for the isolation of proteins at near-native conditions from mammalian tissue for proteomic analysis on antibody microarrays. J. Prot. Res. 9, 963-971.

1082    Ammerpohl O., Pratschke J., Schafmayer C.,  Faber W., van Kampen O., Brosch M., Sipos B., Balschun K., Röcken C., Arlt A., Schniewind B., Grauholm J., Kalthoff H., Neuhaus P., Stickel F., Schreiber S., Bröring D., Siebert R., Hampe J. Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma, Hepatology 2010

1081    Andrulis M, Capper D, Luft T, Hartmann C, Zentgraf H, von Deimling A. Detection of isocitrate dehydrogenase 1 mutations R132H in myelodysplastic syndrome by mutation specific antibody and direct sequencing. Leuk Res. 2010 Mar 11

1080    Anliker, B., Abel,T., Kneissl,S., Hlavaty, J., Caputi, A., Brynza, J., Schneider, I. C.,  Muench, R. C., Petznek, H., Kontermann, R. E., Koehl, U., Johnston, I. C. D., Keinänen, K., Müller, U. C., Hohenadl, C., Monyer, H., Cichutek, K., and Buchholz, C. J. Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors. Nature Methods 7:929-35

1079    Ansén S, Bangard C, Querings S, Gabler F, Scheffler M, Seidel D, Saal B, Zander T, Nogová L, Töpelt K, Markert E, Stoelben E, Ernestus K, Thomas RK, Wolf J. Osteoblastic response in patients with non-small cell lung cancer with activating EGFR Mutations and bone metastases during treatment with EGFR kinase inhibitors.  J Thorac Oncol. 2010 Mar;5(3):407-9.

1078    Antonchick, A. C. Gerding-Reimers, M. Catarinella, S. Ziegler, D. Rauh and H. Waldmann. Highly Enantioselective Synthesis and Cellular Evaluation of Natural Product-Inspired Spirooxindoles, Nature Chemistry, 2010, 2(9):735-40

1077    Anttila V, Stefansson H, Kallela M, Todt U, Terwindt GM, Calafato MS, Nyholt DR, Dimas AS, Freilinger T, Müller-Myhsok B, Artto V, Inouye M, Alakurtti K, Kaunisto MA, Hämäläinen E, de Vries B, Stam AH, Weller CM, Heinze A, Heinze-Kuhn K, Goebel I, Borck G, Göbel H, Steinberg S, Wolf C, Björnsson A, Gudmundsson G, Kirchmann M, Hauge A, Werge T, Schoenen J, Eriksson JG, Hagen K, Stovner L, Wichmann HE, Meitinger T, Alexander M, Moebus S, Schreiber S, Aulchenko YS, Breteler MM, Uitterlinden AG, Hofman A, van Duijn CM, Tikka-Kleemola P, Vepsäläinen S, Lucae S, Tozzi F, Muglia P, Barrett J, Kaprio J, Färkkilä M, Peltonen L, Stefansson K, Zwart JA, Ferrari MD, Olesen J, Daly M, Wessman M, van den Maagdenberg AM, Dichgans M, Kubisch C, Dermitzakis ET, Frants RR, Palotie A; International Headache Genetics Consortium. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1 Nature Genetics. 2010 Oct; 42(10):869-873. doi:10.1038/ng.652

1076    Arunachalam V, Stelzl U, Foulle F, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro M, Wanker EE. Constructing directed protein interaction networks for activated EGF/Erk signaling. Molecular Systems Biology. Submitted. 2010

1075    Assimes TL, Hólm H, Kathiresan S, Reilly MP, Thorleifsson G, Voight BF, Erdmann J, Willenborg C, Vaidya D, Xie C, Patterson CC, Morgan TM, Burnett M-S, Li M, Hlatky MA, Knowles J, Thompson JR, Absher D, Iribarren C, Go A, Fortmann S, Sidney S, Risch N, Tang H, Myers RM, Berger K, Stoll M, Shah SH, Thorgeirsson G, Andersen K, Havulinna AS, Herrera JE, Faraday N, Kim Y, Kral BJ, Mathias R, Ruczinski I, Suktitipat B, Wilson AF, Yanek LR, Becker LC, Linsel-Nitschke P, Lieb W, König IR, Hengstenberg C, Fischer M, Stark K, Reinhard W, Winogradow J, Grassl M, Grosshennig A, Preuss M, Schreiber S, Wichmann H-E, Meisinger C, Yee J, Friedlander Y, Do R, Berglund G, Meigs JB, Williams G, Nathan DM, MacRae CA, Qu L, Wilensky R, Jr. WHM, Qasim A, Hakonarson HH, Pichard AD, Kent KM, Satler L, Lindsay JM, Waksman R, Knouff CW, Waterworth DM, Walker MC, Mooser V, Marrugat J, Lucas G, Subirana I, Sala J, Ramos R, Martinelli N, Olivieri O, Trabetti E, Malerba G, Pignatti PF, Surti A, Guiducci C, Mirel D, Parkin M, Burtt N, Gabriel SB, Hirschhorn JN, Asselta R, Duga S, Musunuru K, Daly MJ, Purcell S, Myocardial Infarction Genetics Consortium, Braund PS, Wright BJ, Balmforth AJ, Ball SG, Wellcome Trust Case Control Consortium, Ouwehand W, Deloukas P, Scholz M, Cambien F, Cardiogenics Consortium, Huge A, Scheffold T, Salomaa V, Girelli D, Granger CB, Peltonen L, McKeown PP, Altshuler D, Melander O, Devaney JM, Epstein SE, Rader DJ, Elosua R, Engert JC, Anand S, Hall AS, Ziegler A, O?Donnell CJ, Spertus JA, Siscovick D, Schwartz SM, Becker D, Thorsteinsdottir U, Stefansson K, Schunkert H, Samani NJ, Quertermous T. Lack of association between the Trp719Arg polymorphism in kinesinlike protein 6 and coronary artery disease in 19 case-control studies. Journal of the American College of Cardiology. 56: 1552-63

1074    Atanur SS; Birol I; Guryev V; Hirst M; Hummel O; Morrissey C; Behmoaras J; Fernandez-Suarez XM; Johnson MD; McLaren WM; Patone G; Petretto E; Plessy C; Rockland KS; Rockland C; Saar K; Zhao Y; Carninci P; Flicek P; Kurtz T; Cuppen E; Pravenec M; Huebner N; Jones SJ; Birney E; Aitman TJ. The genome sequence of the spontaneously hypertensive rat: analysis and functional significance. Genome Research 20 (6): 791-803 (2010)

1073    Athanasiu L, Mattingsdal M, Kähler AK, Brown A, Gustafsson O, Agartz I, Giegling I, Muglia P, Cichon S, Rietschel M, Pietiläinen OP, Peltonen L, Bramon E, Collier D, Clair DS, Sigurdsson E, Petursson H, Rujescu D, Melle I, Steen VM, Djurovic S, Andreassen OA. Gene variants associated with schizophrenia in a Norwegian genome-wide study are replicated in a large European cohort. Sep;44(12):748-53.

1072    Azoitei N, Pusapati GV, Kleger A, Möller P, Küfer R, Genze F, Wagner M, van Lint J, Carmeliet P, Adler G, Seufferlein T. Protein kinase D2 is a crucial regulator of tumor cell-endothelial cell communication in gastrointestinal tumors. GUT. 2010; Oct;59(10):1316-30. Epub 2010 Aug 23.

1071    Babovic D, Jiang L, Gantois I, Lawrence AJ, Ferreri V, Schütz G, Waddington J.L, Drago J. Age-related behavioural phenotype and cellular characterization of mice with progressive ablation of D1 dopamine receptor-expressing cells. Behav Brain Res. 2010; 206:78-87. Epub 2009 Sep 4.

1070    Barbalic M, Dupuis J, Dehghan A, Bis JC, Hoogeveen RC, Schnabel RB, Nambi V, Bretler M, Smith NL, Peters A, Lu C, Tracy RP, Aleksic N, Heeriga J, Keaney JF Jr, Rice K, Lip GY, Vasan RS, Glazer NL, Larson MG, Uitterlinden AG, Yamamoto J, Durda P, Haritunians T, Psaty BM, Boerwinkle E, Hofman A, Koenig W, Jenny NS, Witteman JC, Ballantyne C, Benjamin EJ. Large-scale genomic studies reveal central role of ABO in sP-selectin and sICAM-1 levels. Hum Mol Genet 2010;19:1863-72.

1069    Barbosa-Silva A, Soldatos TG, Magalhães ILF, Pavlopoulos GA, Fontaine JF, Andrade-Navarro MA, Schneider R, Ortega JM. LAITOR - literature assistant for identification of terms co-occurrences and relationships. BMC Bioinformatics 2010; 11:70. doi 10.1186/1471-2105-11-70

1068    Barkus C, McHugh SB, Sprengel R, Seeburg PH, Rawlins JN, Bannerman DM. Hippocampal NMDA receptors and anxiety: at the interface between cognition and emotion. Eur J Pharmacol. 2010 Jan 10;626(1):49-56. Epub 2009 Oct 15. Review.

1067    Barysenka A, Dress AW, Schubert W. An information theoretic thresholding method for detecting protein colocalizations in stacks of fluorescence images. Journal of Biotechnology, Volume 149, Issue 3, 1 September 2010, Pages 127-131, doi:10.1016/j.jbiotec.2010.01.009

1066    Becker KF, Berg D, Malinowsky K, Wolff C, Ergin B, Meding S, Walch A, Höfler  H. Update on protein analysis of fixed tissues]. Pathologe. 2010 Oct;31 Suppl2:263-7.

1065    Becker KF, Taylor CR. Liquid Morphology': Immunochemical Analysis of Proteins Extracted From Formalin-fixed Paraffin-embedded Tissues: Combining Proteomics With Immunohistochemistry. Appl Immunohistochem Mol Morphol. 2010 Sep 7. [Epub ahead of print]

1064    Beckmann BM, Holinski-Feder E, Walter MC, Haserück N, Reithmann C, Hinterseer M, Wilde AA, Kääb S. Laminopathy presenting as familial atrial fibrillation. Int J Cardiol. 2010 May 14

1063    Behrens MI, Brüggemann N, Chana P, Venegas P, Kägi M, Parrao T, Orellana P, Garrido C,
Rojas CV Hauke J, Hahnen E, Gonzalez R, Seleme N, Fernandez V, Schmidt A, Binkofski F, Kömpf D, Kubisch C, Hagenah J, Klein C, Ramirez A. Clinical spectrum of Kufor Rakeb Syndrome in the Chilean kindered with ATP13A2 mutations. Mov Disord, im Druck.

1062    Bender C, Henjes F, Fröhlich H, Wiemann S, Korf U and Beißbarth T. Dynamic Deterministic Effects Propagation Networks for learning signalling pathways from reverse phase protein array time series data. Bioinformatics 2010, 26, i596-602.

1061    Berg D, Bronger H, Walch A, Höfler H, Becker KF. Analysis of signalling pathways in formalin-fixed breast cancer tissues]. Pathologe. 2010 Oct;31 Suppl 2:296-9.

1060    Berg D, Hipp S, Malinowsky K, et al. Molecular profiling of signalling pathways in formalin fixed and paraffin embedded cancer tissues. European Journal of Cancer 2010;46:47-55

1059    Berg D, Seppi K, Liepelt I, Schweitzer K, Wollenweber F, Wolf B, Dillmann U, Stockner H, Godau J, Kiechl S, Gaenslen A, Willeit J, Di Santo A, Maetzler W, Gasser T, Poewe W, Behnke S. Enlarged hyperechogenic substantia nigra is related to motor performance and olfaction in the elderly. Mov. Disord 25(10):1464-1469.

1058    Bergboer JG, Zeeuwen PL, Irvine AD, Weidinger S, Giardina E, Novelli G, Den Heijer M, Rodriguez E, Illig T, Riveira-Munoz E, Campbell LE, Tyson J, Dannhauser EN, O'Regan GM, Galli E, Klopp N, Koppelman GH, Novak N, Estivill X, McLean WH, Postma DS, Armour JA, Schalkwijk J. Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis. J Invest Dermatol. 2010 Aug;130(8):2057-61

1057    Bergmans, B. A., Shariati, S. A. M., Habets, R. L.P., Verstreeken, P., Schoonjans, L., Müller, U., Dotti, C., DeStrooper, B. Neurons generated from APP/APLP1/APLP2 triple knockout neurons behave normally in vitro and in vivo: lack of evidence for a cell autonomous role of AP in neuronal differentiation. Stem cells 28: 399-406 (DOI:: 10.1002/stem.296)

1056    Berkel S, Marshall CR, Weiss B, Howe J, Roeth R, Moog U, Endris V, Roberts W, Szatmari P, Pinto D, Bonin M, Riess A, Engels H, Sprengel R, Scherer SW, Rappold GA. Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation. Nat Genet. 2010 Jun;42(6):489-91. Epub 2010 May 16.

1055    Bertram L, Lill CM, Tanzi RE. The genetics of Alzheimer disease: back to the future. Neuron. 2010 Oct 21;68(2):270-81.

1054    Berulava T, Horsthemke B (2010) Comment on: Jowett et al. Genetic variation at the FTO locus influences RBL2 gene expression. Diabetes, 59:e9

1053    Berulava T, Horsthemke B. The obesity-associated SNPs in intron 1 of the FTO gene affect primary transcript levels. Eur J Hum Genet, 9:1054-1056

1052    Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nöthen MM, Nurnberger JI Jr, Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP. Gene, Environment Association Studies Consortium. A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A. 2010 Mar  16;107(11):5082-5087.

1051    Bieschke J, Russ J, Friedrich RP, Ehrnhoefer DE, Wobst H, Neugebauer K, Wanker EE. EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity, Proc Natl Acad Sci U.S.A. Epub 2010 12. Apr.

1050    Bieschke J. Gruener Tee - neue Einsichten fuer einen alten Wirkstoff [Green tea - new insights for an old drug]. Chemie in unserer Zeit 44 (4): 306-307 (2010-08).

1049    Bilkei-Gorzo A, Berner J, Zimmermann J, Wickström R, Racz I, Zimmer A. Increased morphine analgesia and reduced side-effects in mice lacking the tac1-gene Br. J Pharmacol. Accepted

1048    Birkenmeier G, Stegemann C, Hoffmann R, Günther R, Huse K, Birkemeyer C. Posttranslational modification of human glyoxalase 1 indicates redox-dependent regulation. PLoS One. 2010 Apr 29;5(4):e10399.

1047    Boerno S.T., Grimm C., Lehrach H. and Michal-Ruth Schweiger. Next Generation Sequencing Technologies for DNA Methylation Analyses in Cancer Genomics. Epigenomics 2010 April; 2(2): 199-209,

1046    Borgmann, K., Raabe, A., Reuther, S., Szymczak, S., Schlomm, T., Isbarn, H., Gomolka, M., Busjahn, A., Bonin, M., Ziegler, A., Dikomey E.  The potential role of G2- but not of G0-radiosensitivity for predisposition of prostate cancer. Radiotherapy & Oncology 2010;96(1):19-24

1045    Bouman, L., Schlierf, A., Lutz, A.K., Shan, J., Deinlein , A., Kast, J., Galehdar, Z., Palmisano, V., Patenge, N., Berg, D., Gasser, T., Augustin, R., Trümbach, D., Irrcher, I., Park, D., Wurst, W., Kilberg, M.S., Tatzelt, J. and Winklhofer, K.F. Parkin is transcriptionally regulated by ATF4: evidence for an interconnection between mitochondrial stress and ER stress. Cell Death Differ., 2010 Nov 26 [Epub ahead of print].

1044    Brase JC, Johannes M, Schlomm T, Falth M, Haese A, Steuber T, Beissbarth T, Kuner R, Sultmann H. Circulating miRNAs are correlated with tumor progression in prostate cancer. Int J Cancer. doi:10.1002/ijc.25376

1043    Brase JC, Mannsperger H, Frohlich H, Gade S, Schmidt C, Wiemann S, Beissbarth T, Schlomm T, Sültmann H, Korf U. Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification. Proteome Science 2010 June; 8:36 doi:10.1186/1477-5956-8-36

1042    Brase JC, Schmidt M, Fischbach T, Sültmann H, Bojar H, Koelbl H, Hellwig B, Rahnenführer J, Hengstler JG, Gehrmann MC. ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction. Clin Cancer Res. 2010 Apr 15;16(8):2391-401. doi: 10.1158/1078-0432.CCR-09-2471

1041    Brettschneider F, Jankowski V, Günthner T, Salem S, Nierhaus M, Schulz A, Zidek W, Jankowski J. Replacement of acetonitrile by ethanol as solvent in reversed phase chromatography of biomolecules. J Chromatogr B Analyt Technol Biomed Life Sci. 2010

1040    Breuer R, Hamshere ML, Strohmaier J, Mattheisen M, Degenhardt F, Meier S, Paul T, O'Donovan MC, Mühleisen TW, Schulze TG, Nöthen MM, Cichon S, Craddock N, Rietschel M. Independent evidence for the selective influence of GABA(A) receptors on one component of the bipolar disorder phenotype. Mol Psychiatry. 2010 Jun 15. [Epub ahead of print]

1039    Brunner S, Hurni S, Streckeisen P, Mayr G, Albrecht M, Yahiaoui N, Keller B. Intragenic allele pyramiding combines different specificities of wheat Pm3 resistance alleles. Plant J. 2010 Nov;64(3):433-45.

1038    Buch S, Schafmayer C, Völzke H, Seeger M, Miquel JF, Sookoian SC, Egberts JH, Arlt A, Pirola CJ, Lerch MM, John U, Franke A, von Kampen O, Brosch M, Nothnagel M, Kratzer W, Boehm BO, Bröring DC, Schreiber S, Krawczak M, Hampe J. Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition. Gastroenterology. 2010 Dec;139(6):1942-1951.e2. Epub 2010 Sep 15.

1037    Buck AH, Perot J, Chisholm MA, Kumar DS, Tuddenham L, Cognat V, Marcinowski L, Dölken L, Pfeffer S. Post-transcriptional regulation of miR-27 in murine cytomegalovirus infection. RNA. 2010 Feb;16(2):307-15. Epub 2010 Jan 4. PubMedPMID: 20047990; PubMed Central PMCID: PMC2811660.
1036    Budäus L, Isbarn H, Eichelberg C, Lughezzani G, Sun M, Perrotte P, Chun FKH, Steuber T, Ahyai SA, Zacharias M, Suardi M, Fisch M, Schlomm T, Haese A, Heinzer H, Huland H, Montorsi F, Graefen M, Karakiewicz PI. Biochemical recurrence after radical prostatectomy: A case of multiplicative interactionbetween surgical margin status and pathological stage. J Urol, in press, 2010
1035    Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol. 2010 Jul 27;20(14):1263-8.

1034    Buil A, Trégouët DA, Souto JC, Saut N, Germain M, Rotival M, Tiret L, Cambien F, Lathrop M, Zeller T, Alessi MC, Rodriguez de Cordoba S, Münzel T, Wild P, Fontcuberta J, Gagnon F, Emmerich J, Almasy L, Blankenberg S, Soria JM, Morange PE. C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S independent mechanism: results from genome-wide association and gene expression analyses followed bycase-control studies. 2010 Mar 8, [Epub ahead of print]

1033    Burbulla LF, Krebiehl G, Krüger R. Balance is the challgenge ? the impact of mitochondrial dynamics in Parkinson?s disease. Eur J Clin Invest 40(11):1048-60

1032    Burbulla LF, Schelling C, Kato H, Rapaport D, Woitalla D, Schiesling C, Schulte C, Sharma M, Bauer P, Jung S, Nordheim A, Schöls L, Riess O, Krüger R. Dissecting the Role of the Mitochondrial Chaperone Mortalin in Parkinson?s Disease ? Functional Impact of Disease-Related Variants on Mitochondrial Homeostasis. Hum Mol Genet 19(22):4437-52

1031    Cadenas C, Franckenstein D, Schmidt M, Gehrmann M, Hermes M, Geppert B, Schormann W, Maccoux LJ, Schug M, Schumann A, Wilhelm C, Freis E, Ickstadt K, Rahenenfuehrer J, Baumbach JI, Sickmann A, Hengstler JG. Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer.  Breast Cancer Res. 2010 Jun 28;12(3):R44. [Epub ahead of print]. doi:10.1186/bcr2599

1030    Campos B, Wan F, Farhadi M, Ernst A, Zeppernick F, Tagscherer KE, Ahmadi R, Lohr J, Dictus C, Gdynia G, Combs SE, Helmke BM, Roth W, Beckhove P, Lichter P, Unterberg A, Radlwimmer B, Herold-Mende C. Differentiation Therapy Exerts Anti-Tumorigenic, Anti-Angiogenic, Anti-Invasive and  Proapoptotic Effects in Brain Tumor Stem Cell-Derived Tumors. Clin Cancer Res. 2010

1029    Carballo-Carbajal I, Weber-Endress S, Rovelli G, Chan D, Wolozin B, Klein CL, Patenge N, Gasser T, Kahle PJ. Leucine-rich repeat kinase 2 induces alpha-synuclein expression via the extracellular signal-regulated kinase pathway. Cell. Signal 22(5):821-827.

1028    Cario G, Zimmermann M, Romey R, Gesk S, Vater I, Harbott J, Schrauder A, Moericke A, Izraeli S, Akasaka T, Dyer MJ, Siebert R, Schrappe M, Stanulla M. Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol. . Blood 2010 Apr 8.

1027    Chalaris A, Adam N, Sina C, Rosenstiel P, Lehmann-Koch J, Schirmacher P,Hartmann D, Cichy J, Gavrilova O, Schreiber S, Jostock T, Matthews V, Häsler R,Becker C, Neurath MF, Reiss K, Saftig P, Scheller J, Rose-John S. Critical roleof the disintegrin metalloprotease ADAM17 for intestinal inflammation andregeneration in mice. J Exp Med. 2010 Aug 2;207(8):1617-24. Epub 2010 Jul 5.PubMed PMID: 20603312; PubMed Central PMCID: PMC2916135.

1026    Charlet K, Wüstenberg T, Schneider-Hassloff H, Kensche M, Schott BH, Wrase J, Heinz A Improved long-term memory performance for reinforced reward-predicting stimuli ? a pilot study. Eur arch psychiatry clin neurosci 260 (suppl 1): S45, P23

1025    Chavez L, Jozefczuk J, Grimm C, Dietrich J, Timmerman T, Lehrach H, Herwig R and James Adjaye. Computational analysis of genome-wide DNA-methylation during the differentiation of human embryonic stem cells along the endodermal lineage. Genome Res., 2010 Oct; 20(10): 1441-50.

1024    Chen X, Lee G, Maher BS, Fanous AH, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan PF, Shi J, Levinson DF, Gejman PV, Sanders A, Duan J, Owen MJ, Craddock NJ, O'Donovan MC, Blackman J, Lewis D, Kirov GK, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V, Straub RE, Weinberger DR, O'Neill FA, Walsh D, Bronstein M, Darvasi A, Lencz T, Malhotra AK, Rujescu D, Giegling I, Werge T, Hansen T, Ingason A, Nöethen MM, Rietschel M, Cichon S, Djurovic S, Andreassen OA, Cantor RM, Ophoff R, Corvin A, Morris DW, Gill M, Pato CN, Pato MT, Macedo A, Gurling HM, McQuillin A, Pimm J, Hultman C, Lichtenstein P, Sklar P, Purcell SM, Scolnick E, St Clair D, Blackwood DH, Kendler KS. GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia. Mol Psychiatry. 2010 Sep 14.

1023    Chinni SV, Raabe CA, Zakaria R, Randau G, Hock CH, Zemann A, Brosius J, Tang TH, Rozhdestvensky, TS. Experimental identification and characterization of 97novel npcRNA candidates in Salmonella enterica serovar Typhi. Nucleic Acids Res, in press.

1022    Chmielecki J, Peifer M, Jia P, Socci ND, Hutchinson K, Viale A, Zhao Z, Thomas RK, Pao W.  Targeted next-generation sequencing of DNA regions proximal to a conserved GXGXXG signaling motif enables systematic discovery of tyrosine kinase fusions in cancer. Nucleic Acids Res. 2010 Nov 1;38(20):6985-96. Epub 2010 Jun 29

1021    Choquet H, Labrune Y, De Graeve F, Hinney A, Hebebrand J, Scherag A, Lecoeur C, Tauber M, Balkau B, Elliot P, Jarvelin MR, Walley AJ, Besnard P, Froguel P, Meyre D. Lack of Association of CD36 SNPs With Early Onset Obesity: A Meta-Analysis in 9,973 European Subjects. Obesity (Silver Spring). 2010 Oct 21. [Epub ahead of print]

1020    Ciraolo E, Morello F, Hobbs RM, Wolf F, Marone R, Iezzi M, Lu X, Mengozzi G, Altruda F, Sorba G, Guan K, Wymann MP, Hirsch E. Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility. Mol Biol Cell. 2010;21:704-711.

1019    Cirstea IC, Kutsche K, Dvorsky R, Gremer L, Carta C, Horn D, Roberts AE, Lepri F, Merbitz-Zahradnik T, Konig, R, Kratz CP, Pantaleoni F, Dentici ML, Joshi VA, Kucherlapati RS, Mazzanti L, Mundlos S, Patton MA, Silengo MC, Rossi C, Zampino G, Digilio C, Stuppia L, Seemanova E, Pennacchio LA, Gelb BD, Dallapiccola B, Wittinghofer A, Ahmadian MR, Tartaglia M, Zenker M. A restricted spectrum of NRAS mutations causes Noonan syndrome. Nat Genet 42, 27-29. PMID: 19966803

1018    Coomaraswamy J, Kilger E, Wölfing H, Schäfer S, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, Jucker M. Modeling Familial Danish Dementia in mice supports the concept of the amyloid hypothesis of Alzheimer´s disease. Proc. Natl. Acad. Sci. USA, published ahead of print April 12, 2010, doi:10.1073/pnas.1001056107.

1017    Copanaki, E., Chang, S., Vlachos, A., Tschäpe, J.-A., Müller, U. C., Kögel, D., Deller, T. sAPP? antagonizes dendritic degeneration and neuron death triggered by  proteasomal stress. Mol Cell Neurosci 44:386-393

1016    Corbo V, Dalai I, Scardoni M, Barbi S, Beghelli S, Bersani S, Albarello L, Doglioni C, Schott C, Capelli P, Chilosi M, Boninsegna L, Becker KF, Falconi M, Scarpa A. MEN1 in pancreatic endocrine tumors: analysis of gene and protein status in 169 sporadic neoplasms reveals alterations in the vast majority of cases. Endocr Relat Cancer. 2010 Aug 16;17(3):771-83.

1015    Cornejo Castro EM, Waak J, Weber SS, Fiesel FC, Oberhettinger P, Schütz M, Autenrieth IB, Springer W, Kahle PJ. Parkinson's disease-associated DJ-1 modulates innate immunity signaling in Caenorhabditis elegans. J Neural Transm. 2010 May;117(5):599-604.

1014    Czamara D, Bruder J, Becker J, Bartling J, Hoffmann P, Ludwig KU, Müller-Myhsok B, Schulte-Körne G. Association of a rare variant with mismatchnegativity in a region between KIAA0319 and DCDC2 in dyslexia. Behav Genet. 2011 Jan;41(1):110-9. DOI: 10.1007/s10519-010-9413-6

1013    Czwan E, Brors B, Kipling D. Modelling p-value distributions to improvetheme-driven survival analysis of cancer transcriptome datasets. BMC Bioinformatics. 2010 Jan 11;11:19.

1012    De Benedetto A, Rafaels NM, McGirt LY, Ivanov AI, Georas SN, Cheadle C, Berger AE, Zhang K, Vidyasagar S, Yoshida T, Boguniewicz M, Hata T, Schneider LC, Hanifin JM, Gallo RL, Novak N, Weidinger S, Beaty TH, Leung DY, Barnes KC, Beck LA. Tight junction defects in patients with atopic dermatitis. J Allergy Clin Immunol. 2010 Dec 15. [Epub ahead of print]

1011    De Kovel CG, Pinto D, Tauer U, Lorenz S, Muhle H, Leu C, Neubauer BA, Hempelmann A, Callenbach PM, Scheffer IE, Berkovic SF, Rudolf G, Striano P, Siren A, Baykan B, Sander T, Lindhout D, Trenité DG, Stephani U, Koeleman BP. Whole-genome linkage scan for epilepsy-related photosensitivity: A mega-analysis. Epilepsy Res. 2010 May;89(2-3):286-94. Epub 2010 Feb 12.

1010    De Kovel CG, Trucks H, Helbig I, Mefford HC, Baker C, Leu C, Kluck C, Muhle H, von Spiczak S, Ostertag P, Obermeier T, Kleefuß-Lie AA, Hallmann K, Steffens M, Gaus V, Klein KM, Hamer HM, Rosenow F, Brilstra EH, Kasteleijn-Nolst Trenité D, Swinkels ME, Weber YG, Unterberger I, Zimprich F, Urak L, Feucht M, Fuchs K, Møller RS, Hjalgrim H, De Jonghe P, Suls A, Rückert IM, Wichmann HE, Franke A, Schreiber S, Nürnberg P, Elger CE, Lerche H, Stephani U, Koeleman BP, Lindhout D, Eichler EE, Sander T. Recurrent microdeletions at 15q11.2 and 16p13.11 predispose to idiopathic generalized epilepsies. Brain 2010;133:23-32

1009    De Preter K, Vermeulen J, Brors B, Delattre O, Eggert A, Fischer M, Janoueix-Lerosey I, Lavarino C, Maris J, Mora J, Nakagawara A, Oberthür A, Ohira M, Schleiermacher G, Schramm A, Schulte J, Wang Q, Westermann F, Speleman F, Vandesompele J. Accurate outcome prediction in neuroblastoma across independent datasets using a multi-gene signature. Clin Cancer Res, 2010, 16(5):1532-1541.

1008    de Silva S, Mastrangelo MA, Lotta Jr LT, Burris CA, Izsvák Z, Ivics Z, Bowers WJ. HSV. Sleeping Beauty Vector-based Embryonic Gene Transfer Using the HSB5 Mutant: Loss of Apparent Transposition 'Hyperactivity' In Vivo. Hum Gene Ther. 2010 May 27; 21:1603-13. PMID: 20507234

1007    Dekker, F.J., O. Rocks, N. Vartak, S. Menninger, C. Hedberg, R. Balamurugan, S. Wetzel, S. Renner, M. Gerauer, B. Schölermann, M. Rusch, J.W. Kramer, D. Rauh, G.W. Coates, L. Brunsveld, P.I. Bastiaens*, H. Waldmann. Small-molecule inhibition of APT1 affects Ras localization and signaling, Nat Chem Biol, 2010, 6(6):449-56

1006    Deussing JM, Breu J, Kühne C, Kallnik M, Bunck M, Glasl L, Yen YC, Schmidt MV, Zurmühlen R, Vogl AM, Gailus-Durner V, Fuchs H, Hölter SM, Wotjak CT, Landgraf R, de Angelis MH, Holsboer F, Wurst W. Urocortin 3 modulates social discrimination abilities via corticotropin-releasing hormone receptor type 2. J Neurosci. 2010 Jul 7;30(27):9103-16.

1005    Dietl P, Liss B, Felder E, Miklavc P, Wirtz H. Lamellar body exocytosis by cell stretch or purinergic stimulation: possible physiological roles, messengers and mechanisms. Cell Physiol Biochem. 2010;25(1):1-12. doi:10.1159/000272046

1004    Ding J, Gudjonsson JE, Liang L, Stuart PE, Li Y, Chen W, Weichenthal M, Ellinghaus E, Franke A, Cookson W, Nair RP, Elder JT. Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. Am J Hum Genet 2010;87(6):779-89.

1003    Ditzen C, Varadarajulu J, Czibere L, Gonik M, Targosz BS, Hambsch B, Bettecken T, Kessler MS, Frank E, Bunck M, Teplytska L, Erhardt A, Holsboer F, Müller-Myhsok B, Landgraf R, Turck CW. Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways. Mol Psychiatry. 2010 Jul;15(7):702-11. doi:10.1038/mp.2008.146

1002    Dodel R, Spottke A, Gerhard A, Reuss A, Reinecker S, Schimke N, Trenkwalder C, Sixel-Döring F, Herting B, Kamm C, Gasser T, Sawires M, Geser F, Köllensperger M, Seppi K, Kloss M, Krause M, Daniels C, Deuschl G, Böttger S, Naumann M, Lipp A, Gruber D, Kupsch A, Du Y, Turkheimer F, Brooks DJ, Klockgether T, Poewe W, Wenning G, Schade-Brittinger C, Oertel WH, Eggert K. Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial). Mov. Disord 25(1):97-107.

1001    Doehring LC, Heeger C, Aherrahrou Z, Kaczmarek PM, Erdmann J, Schunkert H, Ehlers E. Myeloid CD34+CD13+ precursor cells transdifferentiate into chondrocyte-like cells in atheroscleroticintimalcalcification. Accepted for publication in the American Journal of Pathology. (Volume 177, Issue 1 Pages 473-480, July 2010)

1000    Dölken L, Krmpotic A, Kothe S, Tuddenham L, Tanguy M, Marcinowski L, Ruzsics Z, Elefant N, Altuvia Y, Margalit H, Koszinowski UH, Jonjic S, Pfeffer S. Cytomegalovirus microRNAs facilitate persistent virus infection in salivary glands..PLoS Pathog. 2010 Oct 14;6(10):e1001150.

999    Dölken, L., G. Malterer, F. Erhard, S. Kothe, C. C. Friedel, G. Suffert, L. Marcinowski, N. Motsch, S. Barth, M. Beizinger, D. Lieber, S. Bailer, R. Hoffmann, Z. Ruzsics, E. Kremmer, S. Pfeffer, R. Zimmer, U. H. Koszinowski, F. Grässer, G. Meister and J. Haas. Systemic Analysis of Viral and Cellular miRNA Targets in Cells Latently Infected with Human gamma-Herpesviruses through RISC Immunoprecipitation Assays.' Cell Host & Microbe, 7(4): 324-334.

998    Domenici E, Willé DR, Tozzi F, Prokopenko I, Miller S, McKeown A, Brittain C, Rujescu D, Giegling I, Turck CW, Holsboer F, Bullmore ET, Middleton L, Merlo-Pich E, Alexander RC, Muglia P. Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections. PLoS One. Feb 11;5(2):e9166.

997    Domschke C, Schuetz F, Sommerfeldt N, Rom J, Scharf A, Sohn C, Schneeweiss A, Beckhove P. Effects of distant metastasis and peripheral CA 15-3 on the induction of spontaneous T cell responses in breast cancer patients. Cancer Immunol Immunother 59: 479-486.

996    Dressel R, Nolte J, Elsner L, Novota P, Guan K, Streckfuss-Bömeke K, Hasenfuss G, Jaenisch R, Engel W. Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. FASEB J, 2010; 24:2164-2177.

995    Drews E, Rácz I, Lacava AD, Barth A, Bilkei-Gorzó A, Wienker TF, Zimmer A. Quantitative trait loci contributing to physiological and behavioural ethanolresponses after acute and chronic treatment. Int J Neuropsychopharmacol. 2010 Mar13(2):155-69. DOI: 10.1017/S1461145709990447

994    Drews E, Zimmer A. Modulation of alcohol and nicotine responses through the endogenous opioid system. Prog Neurobiol 90:1-15.

993    Dror AA, Politi Y, Shahin H, Lenz DR, Dossena S, Nofziger C, Fuchs H, Hrabé de Angelis M, Paulmichl M, Weiner S, Avraham KB. Calcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation. J Biol Chem. 285(28):21724-35. doi:10.1074/jbc.M110.120188.

992    Duitama, J., Huebsch, T., McEwen, G., Suk, E., and Hoehe, M. R. 2010. ReFHap: a reliable and fast algorithm for single individual haplotyping. In Proceedings of the First ACM international Conference on Bioinformatics and Computational Biology (Niagara Falls, New York, August 02 - 04, 2010). BCB '10. ACM, New York, NY, 160-169.

991    Dupuis J, Langenberg C, Prokopenko I, Saxena R, Soranzo N, Jackson AU, WheelerE, Glazer NL, Bouatia-Naji N, Gloyn AL, Lindgren CM, Mägi R, Morris AP, RandallJ, Johnson T, Elliott P, Rybin D, Thorleifsson G, Steinthorsdottir V, Henneman P,Grallert H, Dehghan A, Hottenga JJ, Franklin CS, Navarro P, Song K, Goel A, PerryJR, Egan JM, Lajunen T, Grarup N, Sparsø T, Doney A, Voight BF, Stringham HM, Li M, Kanoni S, Shrader P, Cavalcanti-Proença C, Kumari M, Qi L, Timpson NJ, Gieger C, Zabena C, Rocheleau G, Ingelsson E, An P, O'Connell J, Luan J, Elliott A,McCarroll SA, Payne F, Roccasecca RM, Pattou F, Sethupathy P, Ardlie K, Ariyurek Y, Balkau B, Barter P, Beilby JP, Ben-Shlomo Y, Benediktsson R, Bennett AJ,Bergmann S, Bochud M, Boerwinkle E, Bonnefond A, Bonnycastle LL, Borch-Johnsen K,Böttcher Y, Brunner E, Bumpstead SJ, Charpentier G, Chen YD, Chines P, Clarke R, Coin LJ, Cooper MN, Cornelis M, Crawford G, Crisponi L, Day IN, de Geus EJ,Delplanque J, Dina C, Erdos MR, Fedson AC, Fischer-Rosinsky A, Forouhi NG, FoxCS, Frants R, Franzosi MG, Galan P, Goodarzi MO, Graessler J, Groves CJ, GrundyS, Gwilliam R, Gyllensten U, Hadjadj S, Hallmans G, Hammond N, Han X, HartikainenAL, Hassanali N, Hayward C, Heath SC, Hercberg S, Herder C, Hicks AA, Hillman DR,Hingorani AD, Hofman A, Hui J, Hung J, Isomaa B, Johnson PR, Jørgensen T, Jula A,Kaakinen M, Kaprio J, Kesaniemi YA, Kivimaki M, Knight B, Koskinen S, Kovacs P,Kyvik KO, Lathrop GM, Lawlor DA, Le Bacquer O, Lecoeur C, Li Y, Lyssenko V,Mahley R, Mangino M, Manning AK, Martínez-Larrad MT, McAteer JB, McCulloch LJ,McPherson R, Meisinger C, Melzer D, Meyre D, Mitchell BD, Morken MA, Mukherjee S,Naitza S, Narisu N, Neville MJ, Oostra BA, Orrù M, Pakyz R, Palmer CN, PaolissoG, Pattaro C, Pearson D, Peden JF, Pedersen NL, Perola M, Pfeiffer AF, Pichler I,Polasek O, Posthuma D, Potter SC, Pouta A, Province MA, Psaty BM, Rathmann W,Rayner NW, Rice K, Ripatti S, Rivadeneira F, Roden M, Rolandsson O, Sandbaek A,Sandhu M, Sanna S, Sayer AA, Scheet P, Scott LJ, Seedorf U, Sharp SJ, Shields B, Sigurethsson G, Sijbrands EJ, Silveira A, Simpson L, Singleton A, Smith NL, SovioU, Swift A, Syddall H, Syvänen AC, Tanaka T, Thorand B, Tichet J, Tönjes A, TuomiT, Uitterlinden AG, van Dijk KW, van Hoek M, Varma D, Visvikis-Siest S, Vitart V,Vogelzangs N, Waeber G, Wagner PJ, Walley A, Walters GB, Ward KL, Watkins H,Weedon MN, Wild SH, Willemsen G, Witteman JC, Yarnell JW, Zeggini E, Zelenika D, Zethelius B, Zhai G, Zhao JH, Zillikens MC; DIAGRAM Consortium; GIANT Consortium;Global BPgen Consortium, Borecki IB, Loos RJ, Meneton P, Magnusson PK, Nathan DM,Williams GH, Hattersley AT, Silander K, Salomaa V, Smith GD, Bornstein SR,Schwarz P, Spranger J, Karpe F, Shuldiner AR, Cooper C, Dedoussis GV,Serrano-Ríos M, Morris AD, Lind L, Palmer LJ, Hu FB, Franks PW, Ebrahim S, MarmotM, Kao WH, Pankow JS, Sampson MJ, Kuusisto J, Laakso M, Hansen T, Pedersen O,Pramstaller PP, Wichmann HE, Illig T, Rudan I, Wright AF, Stumvoll M, Campbell H,Wilson JF; Anders Hamsten on behalf of Procardis Consortium; MAGIC investigators,Bergman RN, Buchanan TA, Collins FS, Mohlke KL, Tuomilehto J, Valle TT, AltshulerD, Rotter JI, Siscovick DS, Penninx BW, Boomsma DI, Deloukas P, Spector TD,Frayling TM, Ferrucci L, Kong A, Thorsteinsdottir U, Stefansson K, van Duijn CM, Aulchenko YS, Cao A, Scuteri A, Schlessinger D, Uda M, Ruokonen A, Jarvelin MR,Waterworth DM, Vollenweider P, Peltonen L, Mooser V, Abecasis GR, Wareham NJ,Sladek R, Froguel P, Watanabe RM, Meigs JB, Groop L, Boehnke M, McCarthy MI,Florez JC, Barroso I. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010 Feb;42(2):105-16.

990    Eberle I, Pless B, Jacobi M, Dingermann T, Marschalek R. Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells. Nucl Acids Res 38, 5384-5395.

989    Ebert AD, Laussmann M, Wegehingel S, Kaderali L, Erfle H, Reichert J, Lechner J, Beer HD, Pepperkok R, Nickel W. Tec-Kinase-mediated Phosphorylation of Fibroblast Growth Factor 2 Is Essential for Unconventional Secretion. Traffic. doi:10.1111/j.1600-0854.2010.01059.

988    Eggers C, Schmidt A, Hagenah J, Brüggemann N, Klein JC, Tadic V, Kertelge L, Binkofski F, Siebner H, Neumaier B, Fink GR, Hilder R, Klein C. Progression of subtle motor signs in PINK1 mutation carriers with mild dopaminergic deficit. Neurology, im Druck.

987    Eggert A, Schulte JH. A small kiss of death for cancer. Nat Med. 2010;16:1079-81

986    El Gammal AT, Bruchmann M, Zustin J, Isbarn H, Hellwinkel OJ, Kollermann J, Sauter G, Simon R, Wilczak W, Schwarz J, Bokemeyer C, Brummendorf TH, Izbicki JR, Yekebas E, Fisch M, Huland H, Graefen M, Schlomm T. Chromosome 8p deletions and 8q gains are associated with tumor progression and poor prognosis in prostate cancer. Clin Cancer Res 2010;16:56-64.

985    Elbaz A, Ross O, Ioannidis JPA, Soto-Ortolaza AI, Moisan F, Aasly J, Annesi G, Bozi M, Brighina L, Chartier-Harlin MC, Destée A, Ferrarese C, Ferraris A, Gibson JM, Gispert S, Hadjigeorgiou GM, Jasinska-Myga B, Klein C, Krüger R, Lambert JC, Lohmann K, van de Loo S, Loriot MA, Lynch T, Mellick G, Mutez E, Nilsson C, Opala G, Puschmann A,  Quattrone A, Sharma M, Silburn PA, Stefanis L, Uitti RJ, Valente EM, Vilariño-Güell C, Wirdefeldt K, Wszolek ZK, Xiromerisiou G, Maraganore DM, Farrer MJ on behalf of the Genetic Epidemiology Of Parkinson?s Disease (GEO-PD) consortium. Independent and joint effects of the MAPT and SNCA genes in Parkinson?s disease. Ann Neurol. 2010 Oct 29. doi: 10.1002/ana.22321. [Epub ahead of print]

984    Ellinghaus E, Ellinghaus D, Stuart PE, Nair RP, Debrus S, Raelson JV, Belouchi M, Fournier H, Reinhard C, Ding J, Li Y, Tejasvi T, Gudjonsson J, Stoll SW, Voorhees JJ, Lambert S, Weidinger S, Eberlein B, Kunz M, Rahman P, Gladman DD, Gieger C, Wichmann HE, Karlsen TH, Mayr G, Albrecht M, Kabelitz D, Mrowietz U, Abecasis GR, Elder JT, Schreiber S, Weichenthal M, Franke A. Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat Genet 2010;42(11):991-5.

983    Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, Soliman EZ, Rice KM, Van Wagoner DR, Beckmann BM, van Noord C, Wang K, Ehret GB, Rotter JI, Hazen SL, Steinbeck G, Smith AV, Launer LJ, Harris TB, Makino S, Nelis M, Milan DJ, Perz S, Esko T, Köttgen A, Moebus S, Newton-Cheh C, Li M, Möhlenkamp S, Wang TJ, Kao WH, Vasan RS, Nöthen MM, MacRae CA, Stricker BH, Hofman A, Uitterlinden AG, Levy D, Boerwinkle E, Metspalu A, Topol EJ, Chakravarti A, Gudnason V, Psaty BM, Roden DM, Meitinger T, Wichmann HE, Witteman JC, Barnard J, Arking DE, Benjamin EJ, Heckbert SR, Kääb S. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar;42(3):240-4. Epub 2010 Feb 21

982    Emig D, Salomonis N, Baumbach J, Lengauer T, Conklin BR, Albrecht M. AltAnalyze and DomainGraph: analyzing and visualizing exon expression data.Nucleic Acids Res. 2010 Jul 1;38 Suppl:W755-62.

981    Endele S, Rosenberger G, Geider K, Popp B, Tamer C, Stefanova I, Milh M, Kortüm F, Fritsch A, Pientka FK, Hellenbroich Y, Kalscheuer VM, Kohlhase J, Moog U, Rappold G, Rauch A, Ropers HH, von Spiczak S, Tönnies H, Villeneuve N, Villard L, Zabel B, Zenker M, Laube B, Reis A, Wieczorek D, Van Maldergem L, Kutsche K. Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes. Nat Genet. 2010 Nov;42(11):1021-6. Epub 2010 Oct 3

980    Endres, K and Fahrenholz, F. Upregulation of the alpha-secretase ADAM10 - risk or reason for hope?. FEBS J 2010; 277: 1585-1596

979    Endris V*, Hackmann K*, Neuhann TM, Schrock E, Grasshoff U, Bonin M, Haug U, Hahn G, Schallner JC, Tinschert S, Rappold G, Moog U. Nullisomy for the recurrent 680 kb deletion on chromosome 15q13.3 with loss of CHRNA7 causes severe encephalopathy with refractory seizures. Am J Med Genet A. 2010; 152A:2908-11

978    Endris V, Hackmann K, Neuhann TM, Grasshoff U, Bonin M, Haug U, Hahn G, Schallner JC, Schröck E, Tinschert S, Rappold G, Moog U. Homozygous loss of CHRNA7 on chromosome 15q13.3 causes severe encephalopathy with seizures and hypotonia.  Am J Med Genet A. 2010 Nov;152A(11):2908-11.

977    Enokido Y, Tamura T, Ito H, Arumughan A, Komuro A, Shiwaku H, Sone M, Foulle R, Sawada H, Ishiguro H, Ono T, Murata M, Kanazawa I, Tomilin N, Tagawa K, Wanker EE, Okazawa H. Mutant huntingtin impairs Ku70-mediated DNA repair. J Cell Biol. 189:425-43

976    Erdmann J, Linsel-Nitschke P, Schunkert H. Genetic causes of myocardialinfarction: new insights from genome-wide association studies. Dtsch Arztebl Int. 2010 Oct;107(40):694-9. Epub 2010 Oct 8. PubMed PMID: 21031128; PubMed Central PMCID: PMC2965371.

975    Ergin B, Meding S, Langer R, Kap M, Viertler C, Schott C, Ferch U, Riegman P, Zatloukal K, Walch A, Becker KF. Proteomic analysis of PAXgene-fixed tissues. J Proteome Res. 2010 Oct 1;9(10):5188-96.

974    Erhardt A, Czibere L, Roeske D, Lucae S, Unschuld PG, Ripke S, Specht M, Kohli MA, Kloiber S, Ising M, Heck A, Pfister H, Zimmermann P, Lieb R, Pütz B, Uhr M, Weber P, Deussing JM, Gonik M, Bunck M, Keßler MS, Frank E, Hohoff C, Domschke K, Krakowitzky P, Maier W, Bandelow B, Jacob C, Deckert J, Schreiber S, Strohmaier J, Nöthen M, Cichon S, Rietschel M, Bettecken T, Keck ME, Landgraf R, Müller-Myhsok B, Holsboer F, Binder EB. TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies. Mol Psychiatry. 2010 Apr 6.

973    Erk S, Meyer-Lindenberg A, Schnell K, Opitz von Boberfeld C, Esslinger C, Kirsch P, Grimm O, Arnold C, Haddad L, Witt SH, Cichon S, Nöthen MM, Rietschel M, Walter H. Brain function in carriers of a genome-wide supported bipolar disorder variant. Arch Gen Psychiatry. 2010 Aug;67(8):803-11.

972    Erkan M, Weis N, Pan Z, Schwager C, Samkharadze T, Jiang X, Wirkner U, Giese NA, Ansorge W, Debus J, Huber PE, Friess H, Abdollahi A, and Kleeff J. Organ-, Inflammation- and Cancer Specific Transcriptional Fingerprints of Pancreatic and Hepatic Stellate Cells. Mol Cancer 2010, 9:88.

971    Ernst A, Campos B, Meier J, Devens F, Liesenberg F, Wolter M, Reifenberger G, Herold-Mende C, Lichter P, Radlwimmer B. De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures. Oncogene. 2010 Jun 10;29(23):3411-22.

970    Eschenburg G, Stermann A, Preissner R, Meyer HA, Lode HN. DNA vaccination: using the patient's immune system to overcome cancer. Clin Dev Immunol. 2010;2010:169484. Epub 2010 Dec 16

969    Esparza-Gordillo J, Marenholz I, Lee YA. Genome-wide approaches to the etiology of eczema. Curr Opin All Clin Immunol. 2010.

968    Evangelou E, Maraganore DM, Annesi G, Brighina L, Brice A, Elbaz A, Ferrarese C, Hadjigeorgiou GM, Krueger R, Lambert JC, Lesage S, Markopoulou K, Mellick GD, Meeus B, Pedersen NL, Quattrone A, Van Broeckhoven C, Sharma M, Silburn PA, Tan EK, Wirdefeldt K, Ioannidis JP. Genetic Epidemiology of Parkinson's Disease (GEOPD) Consortium. (2010) Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):220-8.

967    Fahrenholz, F, Tippmann, F and Endres, K. Retinoids as a Perspective in Treatment of Alzheimer´s disease. Neurodeg. Dis. 2010 Mar 12;7(1-3):190-192

966    Festen EA, Stokkers PC, van Diemen CC, van Bodegraven AA, Boezen HM, Crusius BJ, Hommes DW, van der Woude CJ, Balschun T, Verspaget HW, Schreiber S, de Jong DJ, Franke A, Dijkstra G, Wijmenga C, Weersma RK. Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk.  .Am J Gastroenterol. 2010 Feb;105(2):395-402. Epub 2009 Oct 27. Erratum in: Am J Gastroenterol. 2010 Feb;105(2):479. van der Woude, Janneke C [corrected to van der Woude, C Janneke].

965    Fett, M.E., Pilsl, A., Paquet, D., Haass, C, Tatzelt, J., Schmid, B. and Winklhofer, K.F. Parkin is protective against proteotoxic stress in a transgenic zebrafish model. PLoS One, 5(7): e11783.

964    Feulner TM, Laws SM, Friedrich P, Wagenpfeil S, Wurst SH, Riehle C, Kuhn KA, Krawczak M, Schreiber S, Nikolaus S, Förstl H, Kurz A, Riemenschneider M. Examination of the current top candidate genes for AD in a genome-wideassociation study. Mol Psychiatry. 2010;15(7):756-66. [Epub ahead of print]

963    Feyder M, Karlsson RM, Mathur P, Lyman M, Bock R, Momenan R, Munasinghe J, Scattoni ML, Strathdee D, Begg A, Alvarez VA, Kirsch P, Rietschl M Cichon S Walter H, Meyer-Lindenberg A, Grant SGN, Holms A. Mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation is associated with phenotypes relevant to autism-spectrum disorders and Williams-Beuren syndrome. American Journal of Psychiatry 167:1508-1517.

962    Fischer A, Nothnagel M, Franke A, Jacobs G, Saadati HR, Gaede KI, Rosenstiel P, Schurmann M, Muller-Quernheim J, Schreiber S, Hofmann S. Association of IBD Risk Loci with Sarcoidosis and its Acute and Chronic Subphenotypes. Eur Respir J 2010.

961    Fischer A, Nothnagel M, Schürmann M, Müller-Quernheim J, Schreiber S, Hofmann S. A genome-wide linkage analysis in 181 German sarcoidosis families using clustered bi-allelic markers. Chest. 2010 Jul;138(1):151-7. Epub 2010 Feb 26. PMID: 20190003

960    Fischer M, Bauer T, Oberthür A, Hero B, Theissen J, Ehrich M, Spitz R, Eils R, Westermann F, Brors B, König R, Berthold F. Integrated genomic profiling identifies two distinct molecular subtypes with divergent outcome in neuroblastoma with loss of chromosome 11q. Oncogene. 2010 Feb 11;29(6):865-75.

959    Fischer-Posovszky P,  von Schnurbein J, Moepps B,  Lahr G, Strauss G, Barth TF, Kassubek J, Mühleder H, Möller P, Debatin KM, Gierschik P, Wabitsch MA. New missense mutation in the leptin gene causes mild obesity and hypogonadism without affecting T cell responsiveness. J Clin Endo Metab. 2010

958    Flachsbart F, Caliebe A, Nothnagel M, Kleindorp R, Nikolaus S, Schreiber S, Nebel A. Depletion of potential A2M risk haplotype for Alzheimer's disease in long-lived individuals. Eur J Hum Genet. 2010 Jan;18(1):59-61. Epub. PMID: 19639019

957    Flaquer A, Jamra RA, Etterer K, Díaz GO, Rivas F, Rietschel M, Cichon S, Nöthen MM, Strauch K. A new susceptibility locus for bipolar affective disorder in PAR1 on Xp22.3/Yp11.3. Am J Med Genet B Neuropsychiatr Genet. 2010 Jul;153B(5):1110-4.

956    Försti A, Li X, Wagner K, Tavelin B, Enquist K, Palmqvist R, Altieri A, Hallmans G, Hemminki K, Lenner P. Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression. Genes Chromosomes Cancer. 2010 Mar;49(3):270-81. doi 10.1002/gcc.20738

955    Frank B, Hoffmeister M, Klopp N, Illig T, Chang-Claude J, Brenner H. Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM. Carcinogenesis. 2010 Mar;31(3):442-5. doi 10.1093/carcin/bgp293

954    Frank B, Hoffmeister M, Klopp N, Illig T, Chang-Claude J, Brenner H. Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk. Int J Cancer 2010 Dec;127(12):2822-30.doi 10.1002/ijc.25299

953    Frank B, Hoffmeister M, Klopp N, Illig T, Chang-Claude J, Brenner H. Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer. Carcinogenesis. 2010 Aug;31(8):1381-6. doi 10.1093/carcin/bgq082

952    Frank D, Frauen R, Hanselmann C, Kuhn C, Will D, Gantenberg J, Füzesi L, Katus HA, Frey N. Lmcd1/Dyxin, a novel Z-disc associated LIM protein, mediates cardiac hypertrophy in vitro and in vivo. (2010) in revision.

951    Franke A, Balschun T, Sina C, Ellinghaus D, Hasler R, Mayr G, Albrecht M, Wittig M, Buchert E, Nikolaus S, Gieger C, Wichmann HE, Sventoraityte J, Kupcinskas L, Onnie CM, Gazouli M, Anagnou NP, Strachan D, McArdle WL, Mathew CG, Rutgeerts P, Vermeire S, Vatn MH, Krawczak M, Rosenstiel P, Karlsen TH, Schreiber S. Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL). Nat Genet 2010;42:292-4.

950    Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew CG, Montgomery GW, Prescott NJ, Raychaudhuri S, Rotter JI, Schumm P, Sharma Y, Simms LA, Taylor KD, Whiteman D, Wijmenga C, Baldassano RN, Barclay M, Bayless TM, Brand S, Buning C, Cohen A, Colombel JF, Cottone M, Stronati L, Denson T, De Vos M, D'Inca R, Dubinsky M, Edwards C, Florin T, Franchimont D, Gearry R, Glas J, Van Gossum A, Guthery SL, Halfvarson J, Verspaget HW, Hugot JP, Karban A, Laukens D, Lawrance I, Lemann M, Levine A, Libioulle C, Louis E, Mowat C, Newman W, Panes J, Phillips A, Proctor DD, Regueiro M, Russell R, Rutgeerts P, Sanderson J, Sans M, Seibold F, Steinhart AH, Stokkers PC, Torkvist L, Kullak-Ublick G, Wilson D, Walters T, Targan SR, Brant SR, Rioux JD, D'Amato M, Weersma RK, Kugathasan S, Griffiths AM, Mansfield JC, Vermeire S, Duerr RH, Silverberg MS, Satsangi J, Schreiber S, Cho JH, Annese V, Hakonarson H, Daly MJ, Parkes M. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet 2010;42:1118-25.

949    Freiwald A, Mao L, Kodelja V, Kliem M, Schuldt D, Schreiber S, Franke A and Sauer S. Differential analysis of crohn disease and ulcerative colitis by mass spectrometry. Inflammatory Bowel Diseases, in press

948    Friedel CC, Kaufmann S, Dölken L, Zimmer R. HALO - A Java framework forprecise transcript half-life determination. Bioinformatics. 2010 Mar 17. [Epubahead of print] PubMed PMID: 20299326.

947    Galiveti CR, Rozhdestvensky TS, Brosius J, Lehrach H, Konthur Z. Application of housekeeping npcRNAs for quantitative expression analysis of human transcriptome by real-time PCR. RNA 16:450-461. Epub 2009 Dec 29.

946    Gallinat J, Schubert F, Brühl R, Hellweg R, Klär AA, Kehrer C, Wirth C, Sander T, Lang UE. Met carriers of BDNF Val66Met genotype show increased N-acetylaspartate concentration in the anterior cingulate cortex. Neuroimage. 2010 Jan 1;49(1):767-71. Epub 2009 Aug 13.

945    Gehlenborg N, O'Donoghue SI, Baliga NS, Goesmann A, Hibbs MA, Kitano H, Kohlbacher O, Neuweger H, Schneider R, Tenenbaum D, Gavin AC. Visualization of omics data for systems biology. Nat Methods 7: S56-68.

944    Geisler S, Holmström KM, Skujat D, Fiesel FC, Rothfuss OC, Kahle PJ, Springer W. PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat Cell Biol. 2010 Feb;12(2):119-31.

943    Geisler S, Holmström KM, Treis A, Skujat D, Weber SS, Fiesel FC, Kahle PJ, Springer W. The PINK1/Parkin-mediated mitophagy is compromised by PD-associated mutations. Autophagy. 2010 Oct 1;6(7):871-8.

942    Gerdes S, Zahl VA, Weichenthal M, Mrowietz U. Smoking and alcohol intake in severely affected patients with psoriasis in Germany. Dermatology 2010; 220(1):38-43. PMID: 19996578

941    Gierthmühlen J, Schumacher S, Deuschl G, Fritzer E, Klein C, Baron R, Helmchen C. Somatosensory function in asymptomatic parkin mutation carriers. Eur J Neurol, im Druck.

940    Gloeckner CJ, Boldt K, von Zweydorf F, Helm S, Wiesent L, Sarioglu H, Ueffing M. Phosphopeptide analysis reveals two discrete clusters of phosphorylation inthe N-terminus and the Roc domain of the Parkinson-disease associated proteinkinase LRRK2. J Proteome Res. 2010 Apr 5;9(4):1738-45.  doi 10.1021/pr9008578

939    Gloriam, D.E., Orchard, S., Bertinetti, D., Bjorling, E., Bongcam-Rudloff, E., Bourbeillon, J., Bradbury, A.R., de Daruvar, A., Dübel, S., Frank, R., Gibson, T.J., Haslam, N., Herberg, F.W., Hiltke, T., Hoheisel, J.D., Kerrien, S., Koegl, M., Konthur, Z., Korn, B., Landegren, U., van der Maarel, S., Montecchi-Palazzi, L., Palcy, S., Rodriguez, H., Schweinsberg, S., Sievert, V., Stoevesandt, O., Taussig, M.J., Uhlen, M., Wingren, C., Gold, L., Woollard, P., Sherman, D.J. & Hermjakob, H. A community standard for the representation of protein affinity reagents. Mol. Cell. Prot. 9, 1-10.

938    Goehler H, Dröge A, Lurz R, Schnoegl S, Chernoff YO, Wanker EE. Pathogenic polyglutamine tracts are potent inducers of spontaneous Sup35 and Rnq1 amyloidogenesis. PLoS ONE. 2010 Mar; 5 (3):e9642. doi 10.1371/journal.pone.0009642

937    Gogolin S, Dreidax D, Becker G, Ehemann V, Schwab M, Westermann. F.MYCN/MYC-mediated drug resistance mechanisms in neuroblastoma. Int J ClinPharmacol Ther. 2010 Jul;48(7):489-91.

936    Gould CM, Diella F, Via A, Puntervoll P, Gemünd C, Chabanis-Davidson S, Michael S, Sayadi A, Bryne JC, Chica C, Seiler M, Davey NE, Haslam N, Weatheritt RJ, Budd A, Hughes T, Pas J, Rychlewski L, Travé G, Aasland R, Helmer-Citterich M, Linding R, Gibson TJ. ELM: the status of the 2010 eukaryotic linear motif resource. Nucleic Acids Res. 2010 Jan;38:D167-80. Epub 2009 Nov 17.

935    Grabe HJ, Mahler J, Witt SH, Schulz A, Appel K, Spitzer C, Stender J, Barnow S, Freyberger HJ, Teumer A, Völzke H, Rietschel M. A risk marker for alcohol dependence on chromosome 2q35 is related to neuroticism in the general population. Mol Psychiatry. 2010 Mar 30. [Epub ahead of print] PMID: 20351720

934    Grallert H, Herder C, Marzi C, Meisinger C, Wichmann HE, Rathmann W, Illig T. "Association of genetic variation in KCNQ1 with type 2 diabetes in the KORA surveys." Horm Metab Res. 2010 Feb;42(2):149-51. Epub 2009 Oct 1.

933    Granovskaia MV, Jensen LJ, Ritchie ME, Toedling J, Ning Y, Bork P, Huber W, Steinmetz LM. High-resolution transcription atlas of the mitotic cell cycle in budding yeast. Genome Biol. 2010 Mar 1; 11(3):R24. doi 10.1186/gb-2010-11-3-r24

932    Gratacòs M, Escaramís G, Bustamante M, Saus E, Agüera Z, Bayés M, Cellini E, de Cid R, Fernández-Aranda F, Forcano L, González JR, Gorwood P, Hebebrand J, Hinney A, Mercader JM, Nacmias B, Ramoz N, Ribasés M, Ricca V, Romo L, Sorbi S, Versini A, Estivill X. Role of the neurotrophin network in eating disorders' subphenotypes: body mass index and age at onset of the disease. J Psychiatr Res. 2010 Oct;44(13):834-40. Epub 2010 Mar 9. PubMed PMID: 20219210.

931    Grecco HE, Roda-Navarro P, Girod A, Hou J, Frahm T, Truxius DC, Pepperkok R, Squire A, Bastiaens PI. In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays. Nat Methods 7: 467-472.

930    Gremer L, De Luca A, Merbitz-Zahradnik T, Dallapiccola B, Morlot S, Tartaglia M, Kutsche K, Ahmadian MR, Rosenberger G. Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation. Hum Mol Genet 19, 790-802. PMID: 19995790

929    Gremer L, Merbitz-Zahradnik T, Dvorsky R, Cirstea IC, Kratz CP, Zenker M, Wittinghofer A,  Ahmadian M. Impacts of germline mutations in KRAS on the GTPase cycle and effector interaction. Hum Mutat 32, 33-43. PMID: 20949621

928    Grigoroiu-Serbanescu M, Herms S, Diaconu CC, Jamra RA, Meier S, Bleotu C, Neagu AI, Prelipceanu D, Sima D, Gherghel M, Mihailescu R, Rietschel M, Nöthen MM, Cichon S, Mühleisen TW. Possible association of different G72/G30 SNPs with mood episodes and persecutory delusions in bipolar I Romanian patients. Progress in Neuro-Psychopharmacology & Biological Psychiatry 34:657-63. doi:10.1016/j.pnpbp.2010.03.008

927    Grösgen, S., M.O. Grimm, P. Friess, T. Hartmann T. Role of amyloid beta inlipid homeostasis. Biochim Biophys Acta 1801: 966-974.

926    Grote A, Kovacs A, Clusmann H, Becker AJ, Niehusmann P. Incidental pituicytoma after accidental head trauma - case report and review of literature. Clin Neuropathol. 2010, 29(3):127-133

925    Groth M, Wiegand C, Szafranski K, Huse K, Kramer M, Rosenstiel P, Schreiber S, Norgauer J, Platzer M. Both copy number and sequence variations affect expression of human DEFB4. Genes Immun. 2010 Sep;11(6):458-66.

924    Günther T, Schmitt AO, Bortfeldt RH, Hinney A, Hebebrand J, Brockmann GA. Where in the genome are significant single nucleotide polymorphismsfrom genome-wide association studies located?  OMICS: A Journal of Integrative Biology. 2010; accepted

923    Haebig, K, Gloeckner, CJ, Miralles, MG, Gillardon, F, Schulte, C, Riess, O, Ueffing, M, Biskup, S, and Bonin, M. ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2. PLoS One 2010 Oct. 29; 5 (10), e13762. doi: 10.1371/journal.pone.0013762.

922    Hageman RS, Wagener A, Hantschel C, Svenson KL, Churchill GA, Brockmann GA. High fat diet leads to increased storage of mono-unsaturated fatty acids and tissue specific risk factors for diseases in DBA/2 mice. Physiol. Genomics. 2010; 42:55-66.

921    Haller F, Von Heydebreck A, Zhang J, Gunawan B, Langer C, Ramadori G, Wiemann S, Sahin O. Localisation- and mutation-dependent microRNA (miRNA) expression signatures in gastrointestinal stromal tumors (GISTs), with a cluster of coexpressed miRNAs located at 14q32.31. J Pathol 220: 71-86.

920    Hangen E, De Zio D, Bordi M, Zhu C, Dessen P, Caffin F, Lachkar S, Perfettini JL, Lazar V, Benard J, Fimia GM, Piacentini M, Harper F, Pierron G, Vicencio JM, Bénit P, de Andrade A, Höglinger G, Culmsee C, Rustin P, Blomgren K, Cecconi F, Kroemer G, Modjtahedi N. A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2. Cell Death Differ. 2010;17:1155-66.

919    Hartmann C, Hentschel B, Wick W, Capper C, Felsberg J, Simon M, Westphal M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler, M, von Deimling A. Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1 mutated glioblastomas and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. Acta Neuropathol. 2010 Dec;120(6):707-18. Epub 2010 Nov 19.

918    Hebebrand J, Bammann K, Hinney A. Genetic determinants of obesity. Current issues]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2010 Jul;53(7):674-80. Review. German. PubMed PMID: 20631977.

917    Hebebrand J, Scherag A, Schimmelmann BG, Hinney A. Child and adolescentpsychiatric genetics. Eur Child Adolesc Psychiatry. 2010 Mar;19(3):259-79. Epub 2010 Feb 6. PubMed PMID: 20140632.

916    Hebebrand J, Volckmar AL, Knoll N, Hinney A. Chipping away the 'missingheritability': GIANT steps forward in the molecular elucidation of obesity - but still lots to go. Obes Facts. 2010 Oct;3(5):294-303. Epub 2010 Oct 15. Review.PubMed PMID: 20975295.

915    Hebebrand J. The ongoing identification of novel obesity genes. Obes Facts.2010 Jun;3(3):157-8. Epub 2010 Jun 18. PubMed PMID: 20616604.

914    Hegge S, Kudryashev M, Barniol L, Frischknecht F. Key factors regulating Plasmodium berghei sporozoite survival and transformation revealed by an automated visual assay. FASEB J. 2010 Dec; 24: 5003-5012

913    Heid IM, Henneman P, Hicks A, Coassin S, Winkler T, Aulchenko YS, Fuchsberger C, Song K, Hivert MF, Waterworth DM, Timpson NJ, Richards JB, Perry JR, Tanaka T, Amin N, Kollerits B, Pichler I, Oostra BA, Thorand B, Frants RR, Illig T, Dupuis J, Glaser B, Spector T, Guralnik J, Egan JM, Florez JC, Evans DM, Soranzo N, Bandinelli S, Carlson OD, Frayling TM, Burling K, Smith GD, Mooser V, Ferrucci L, Meigs JB, Vollenweider P, Dijk KW, Pramstaller P, Kronenberg F, van Duijn CM. "Clear detection of ADIPOQ locus as the major gene for plasma adiponectin: results of genome-wide association analyses including 4659 European individuals." Atherosclerosis. 2010 Feb;208(2):412-20. Epub 2009 De

911 Heinig M, Petretto E, Wallace C, Bottolo L, Rotival M, Lu H, Li Y, Sarwar R, Langley SR, Bauerfeind A, Hummel O, Lee YA, Paskas S, Rintisch C, Saar K, Cooper J, Buchan R, Gray EE, Cyster JG; Cardiogenics Consortium, Erdmann J, Hengstenberg C, Maouche S, Ouwehand WH, Rice CM, Samani NJ, Schunkert H, Goodall AH, Schulz H, Roider HG, Vingron M, Blankenberg S, Münzel T, Zeller T, Szymczak S, Ziegler A, Tiret L, Smyth DJ, Pravenec M, Aitman TJ, Cambien F, Clayton D, Todd JA, Hubner N, Cook SA. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature. 2010 Sep 23;467(7314):460-4

910 Heller A, Zörnig I, Müller T, Giorgadze K, Frei C, Giese T, Bergmann F, Schmidt J, Werner J, Buchler MW, Jaeger D, Giese NA. Immunogenicity of SEREX-identified antigens and disease outcome in pancreatic cancer. Cancer Immunol Immunother. 2010 Sep;59(9):1389-400. Epub 2010 Jun 1.

909 Hellmann JK, Münter S, Wink M, Frischknecht F. Differential effects of the green tea compound EGCG and digitonin on Plasmodium sporozoite motility and viability. PlosONE. 2010, 5, e8682.

908 Hellwig B, Hengstler JG, Schmidt M, Gehrmann MC, Schormann W, Rahnenführer J. Comparison of scores for bimodality of gene expression distributions and genome-wide evaluation of the prognostic relevance of high-scoring genes. BMC Bioinformatics. 2010 May 25;11:276.doi: 10.1186/1471-2105-11-276

907 Hemminki K, Li X, Sundquist K, Sundquist J. Familial association of inflammatory bowel diseases with other autoimmune and related diseases. Am J Gastroenterol. 2010 Jan;105(1):139-47. doi 10.1038/ajg.2009.496

906 Henze AT, Acker T. Feedback regulators of hypoxia-inducible factors and their role in cancer biology. Cell Cycle, 15;9(14):2749-63

905 Herold J, Schubert W, Nattkemper TW. Automated detection and quantification of fluorescently labeled synapses in murine brain tissue sections for high throughput applications. Journal of Biotechnology, Volume 149, Issue 4, 15 September 2010, Pages 299-309, doi:10.1016/j.jbiotec.2010.03.004

904 Hinney A, Vogel CI, Hebebrand J. From monogenic to polygenic obesity: recentadvances. Eur Child Adolesc Psychiatry. 2010 Mar;19(3):297-310. Epub 2010 Feb 3. PubMed PMID: 20127379; PubMed Central PMCID: PMC2839509.

903 Hipp S, Berg D, Ergin B, Schuster T, Hapfelmeier A, Walch A, Avril S, Schmalfeldt B, Höfler H, Becker KF. Interaction of Snail and p38 mitogen activated protein kinase results in shorter overall survival of ovarian cancer patients. Virchows Arch. 2010 Dec;457(6):705-13.

902 Holdt LM, Beutner F, Scholz M, Gielen S, Gäbel G, Bergert H, Schuler G, Thiery J, Teupser D. ANRIL expression is associated with atherosclerosis risk at chromosome 9p21. Arterioscler Thromb Vasc Biol. 2010 Mar;30(3):620-7. Epub 2010 Jan 7.

901 Holm K, Melum E, Franke A, Karlsen TH. SNPexp - A web tool for calculating and visualizing correlation between HapMap genotypes and gene expression levels. BMC Bioinformatics 2010;11:600.
900    Holzapfel C, Grallert H, Baumert J, Thorand B, Döring A, Wichmann HE, Hauner H, Illig T, Mielck A. "First investigation of two obesity-related loci (TMEM18, FTO) concerning their association with educational level as well as income: the MONICA/KORA study." J Epidemiol Community Health. 2011 Feb;65(2):174-6. Epub 2010 Jul 13.

899    Holzapfel C, Grallert H, Huth C, Wahl S, Fischer B, Döring A, Rückert IM, Hinney A, Hebebrand J, Wichmann HE, Hauner H, Illig T, Heid IM. "Genes and lifestyle factors in obesity: results from 12 462 subjects from MONICA/KORA." Int J Obes (Lond) 34(10), 1538-1545 (2010)

898    Holzapfel C, Siegrist M, Rank M, Langhof H, Grallert H, Baumert J, Irimie C, Klopp N, Wolfarth B, Illig T, Hauner H, Halle M. "Association of a melatonin receptor 1B (MTNR1B) gene variant with fasting glucose and HOMA-B in children and adolescents of high BMI-SDS groups." Eur J Endocrinol. 2011 Feb;164(2):205-212. Epub 2010 Nov 8.

897    Homolka S, Meyer CG, Hillemann D, Owusu-Dabo E, Adjei O, Horstmann RD, Browne EN, Chinbuah A, Osei I, Gyapong J, Kubica T, Ruesch-Gerdes S, Niemann S. Unequal distribution of resistance-conferring mutations among Mycobacterium tuberculosis and Mycobacterium africanum strains from Ghana. Int J Med Microbiol. 2010 Nov;300(7):489-95.

896    Horn D, Johannes Kapeller, Núria Rivera-Brugués, Ute Moog, Bettina Lorenz-Depiereux, Sebastian Eck, Maja Hempel, Janine Wagenstaller, Alex Gawthrope, Anthony P. Monaco, Michael Bonin, Olaf Riess, Eva Wohlleber, Thomas Illig, Connie R. Bezzina, Andre Franke, Stephanie Spranger, Pablo Villavicencio-Lorini, Wenke Seifert, Jochen Rosenfeld, Eva Klopocki, Gudrun A. Rappold and Tim M. Strom. Identification of FOXP1 Deletions in Three Unrelated Patients with Mental Retardation and Significant Speech and Language Deficits. Human Mutation 31:E1851-60, 2010

895    Horstmann S, Lucae S, Menke A, Hennings JM, Ising M, Roeske D, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment. Neuropsychopharmacology. 2010 Feb;35(3):727-40. Epub 2009 Nov 18

894    Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E,Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH; IBSEN Study Group, Stokkers PC, Vermeire S, Mathew CG, Lie BA, Beuers U, Manns MP, Schreiber S, Schrumpf E, Häussinger D, Franke A, Karlsen TH. Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis. PLoS One. 2010 Aug 25;5(8):e12403

893    Huber M, Völler H, Jakob S, Reibisa R, Do V, Bolbrinker J, Schmieder RE, Wegscheider K, Kreutz R. Role of the angiotensin II type 2-receptor gene (+1675G/A) polymorphism on left ventricular hypertrophy and geometry in treated hypertensive patients. J Hypertens. 2010 Jun;28(6):1221-9

892    Hubner N*, Alexander W. Bird*, Jürgen Cox, Bianca Splettstoesser, Peter Bandilla, Ina Poser, Anthony A. Hyman and Matthias Mann. Quantitative proteomics combined with BAC TransgeneOmics reveals in-vivo protein interactions. J Cell Biol. 2010 May 17;189(4):739-54. doi 10.1083/jcb.200911091

891    Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science. 2010 Apr 30;328(5978):593-9.

890    Huth J, Buchholz M, Kraus JM, Schmucker M, von Wichert G, Krndija D, Seufferlein T, Gress TM, Kestler HA. Significantly improved precision of cell migration analysis in time-lapse video microscopy through use of a fully automated tracking system. BMC Cell Biol, 11:24, 2010.

889    Illig T, Gieger C, Zhai G, Römisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmüller G, Kato BS, Mewes HW, Meitinger T, de Angelis MH, Kronenberg F,Soranzo N, Wichmann HE, Spector TD, Adamski J, Suhre K. A genome-wide perspectiveof genetic variation in human metabolism. Nat Genet. 2010 Feb;42(2):137-41. Epub 2009 Dec 27.

888    Imig, J., Motsch, N., Zhu, J. Y., Barth, S., Okoniewski, M., Reineke, T., Tinguely, M., Faggioni, A., Trivedi, P., Meister, G., Renner, C., and Grässer, F. A. microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma. Nucleic Acids Res.

887    Ingason A, Giegling I, Cichon S, Hansen T, Rasmussen HB, Nielsen J, Jürgens G, Muglia P, Hartmann AM, Strengman E, Vasilescu C, Mühleisen TW, Djurovic S, Melle I, Lerer B, Möller HJ, Francks C, Pietiläinen OP, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Walshe M, Vassos E, Di Forti M, Murray R, Bonetto C, Tosato S; GROUP Investigators, Cantor RM, Rietschel M, Craddock N, Owen MJ, Peltonen L, Andreassen OA, Nöthen MM, St Clair D, Ophoff RA, O'Donovan MC, Collier DA, Werge T, Rujescu D. A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia. Hum Mol Genet. Apr 1;19(7):1379-86.

886    Inta D, Monyer H, Sprengel R, Meyer-Lindenberg A, Gass P. Mice with genetically altered glutamate receptors as models of schizophrenia: a comprehensive review. Neurosci Biobehav Rev. 2010 Mar;34(3):285-94. Epub 2009 Aug 3. Review.

885    International Cancer Genome Consortium, Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, Kerr D, Klatt P, Kolar P, Kusada J, Lane DP, Laplace F, Youyong L, Nettekoven G, Ozenberger B, Peterson J, Rao TS, Remacle J, Schafer AJ, Shibata T, Stratton MR, Vockley JG, Watanabe K, Yang H, Yuen MM, Knoppers BM, Bobrow M, Cambon-Thomsen A, Dressler LG, Dyke SO, Joly Y, Kato K, Kennedy KL, Nicolás P, Parker MJ, Rial-Sebbag E, Romeo-Casabona CM, Shaw KM, Wallace S, Wiesner GL, Zeps N, Lichter P, Biankin AV, Chabannon C, Chin L, Clément B, de Alava E, Degos F, Ferguson ML, Geary P, Hayes DN, Hudson TJ, Johns AL, Kasprzyk A, Nakagawa H, Penny R, Piris MA, Sarin R, Scarpa A, Shibata T, van de Vijver M, Futreal PA, Aburatani H, Bayés M, Botwell DD, Campbell PJ, Estivill X, Gerhard DS, Grimmond SM, Gut I, Hirst M, López-Otín C, Majumder P, Marra M, McPherson JD, Nakagawa H, Ning Z, Puente XS, Ruan Y, Shibata T, Stratton MR, Stunnenberg HG, Swerdlow H, Velculescu VE, Wilson RK, Xue HH, Yang L, Spellman PT, Bader GD, Boutros PC, Campbell PJ, Flicek P, Getz G, Guigó R, Guo G, Haussler D, Heath S, Hubbard TJ, Jiang T, Jones SM, Li Q, López-Bigas N, Luo R, Muthuswamy L, Ouellette BF, Pearson JV, Puente XS, Quesada V, Raphael BJ, Sander C, Shibata T, Speed TP, Stein LD, Stuart JM, Teague JW, Totoki Y, Tsunoda T, Valencia A, Wheeler DA, Wu H, Zhao S, Zhou G, Stein LD, Guigó R, Hubbard TJ, Joly Y, Jones SM, Kasprzyk A, Lathrop M, López-Bigas N, Ouellette BF, Spellman PT, Teague JW, Thomas G, Valencia A, Yoshida T, Kennedy KL, Axton M, Dyke SO, Futreal PA, Gerhard DS, Gunter C, Guyer M, Hudson TJ, McPherson JD, Miller LJ, Ozenberger B, Shaw KM, Kasprzyk A, Stein LD, Zhang J, Haider SA, Wang J, Yung CK, Cross A, Liang Y, Gnaneshan S, Guberman J, Hsu J, Bobrow M, Chalmers DR, Hasel KW, Joly Y, Kaan TS, Kennedy KL, Knoppers BM, Lowrance WW, Masui T, Nicolás P, Rial-Sebbag E, Rodriguez LL, Vergely C, Yoshida T, Grimmond SM, Biankin AV, Bowtell DD, Cloonan N, deFazio A, Eshleman JR, Etemadmoghadam D, Gardiner BA, Kench JG, Scarpa A, Sutherland RL, Tempero MA, Waddell NJ, Wilson PJ, McPherson JD, Gallinger S, Tsao MS, Shaw PA, Petersen GM, Mukhopadhyay D, Chin L, DePinho RA, Thayer S, Muthuswamy L, Shazand K, Beck T, Sam M, Timms L, Ballin V, Lu Y, Ji J, Zhang X, Chen F, Hu X, Zhou G, Yang Q, Tian G, Zhang L, Xing X, Li X, Zhu Z, Yu Y, Yu J, Yang H, Lathrop M, Tost J, Brennan P, Holcatova I, Zaridze D, Brazma A, Egevard L, Prokhortchouk E, Banks RE, Uhlén M, Cambon-Thomsen A, Viksna J, Ponten F, Skryabin K, Stratton MR, Futreal PA, Birney E, Borg A, Børresen-Dale AL, Caldas C, Foekens JA, Martin S, Reis-Filho JS, Richardson AL, Sotiriou C, Stunnenberg HG, Thoms G, van de Vijver M, van't Veer L, Calvo F, Birnbaum D, Blanche H, Boucher P, Boyault S, Chabannon C, Gut I, Masson-Jacquemier JD, Lathrop M, Pauporté I, Pivot X, Vincent-Salomon A, Tabone E, Theillet C, Thomas G, Tost J, Treilleux I, Calvo F, Bioulac-Sage P, Clément B, Decaens T, Degos F, Franco D, Gut I, Gut M, Heath S, Lathrop M, Samuel D, Thomas G, Zucman-Rossi J, Lichter P, Eils R, Brors B, Korbel JO, Korshunov A, Landgraf P, Lehrach H, Pfister S, Radlwimmer B, Reifenberger G, Taylor MD, von Kalle C, Majumder PP, Sarin R, Rao TS, Bhan MK, Scarpa A, Pederzoli P, Lawlor RA, Delledonne M, Bardelli A, Biankin AV, Grimmond SM, Gress T, Klimstra D, Zamboni G, Shibata T, Nakamura Y, Nakagawa H, Kusada J, Tsunoda T, Miyano S, Aburatani H, Kato K, Fujimoto A, Yoshida T, Campo E, López-Otín C, Estivill X, Guigó R, de Sanjosé S, Piris MA, Montserrat E, González-Díaz M, Puente XS, Jares P, Valencia A, Himmelbaue H, Quesada V, Bea S, Stratton MR, Futreal PA, Campbell PJ, Vincent-Salomon A, Richardson AL, Reis-Filho JS, van de Vijver M, Thomas G, Masson-Jacquemier JD, Aparicio S, Borg A, Børresen-Dale AL, Caldas C, Foekens JA, Stunnenberg HG, van't Veer L, Easton DF, Spellman PT, Martin S, Barker AD, Chin L, Collins FS, Compton CC, Ferguson ML, Gerhard DS, Getz G, Gunter C, Guttmacher A, Guyer M, Hayes DN, Lander ES, Ozenberger B, Penny R, Peterson J, Sander C, Shaw KM, Speed TP, Spellman PT, Vockley JG, Wheeler DA, Wilson RK, Hudson TJ, Chin L, Knoppers BM, Lander ES, Lichter P, Stein LD, Stratton MR, Anderson W, Barker AD, Bell C, Bobrow M, Burke W, Collins FS, Compton CC, DePinho RA, Easton DF, Futreal PA, Gerhard DS, Green AR, Guyer M, Hamilton SR, Hubbard TJ, Kallioniemi OP, Kennedy KL, Ley TJ, Liu ET, Lu Y, Majumder P, Marra M, Ozenberger B, Peterson J, Schafer AJ, Spellman PT, Stunnenberg HG, Wainwright BJ, Wilson RK, Yang H. International network of cancer genome projects. Nature. 2010 Apr 15;464(7291):993-8.

884    Irrcher, I., Aleyasin, H., Seifert, E.L., Hewitt, S.J., Chhabra, S., Phillips, M., Lutz, A.K., Rousseaux, M.W., Bevilacqua, L., Jahani-Asl, A., Callaghan, S., Maclaurin, J.G., Winklhofer, K.F., Rizzu, P., Rippstein, P., Kim, R.H., Chen, C.X., Fon, E.A., Slack, R.S., Harper, M.E., McBride, H.M., Mak, T.W. and Park, D.S. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Hum Mol Genet, 19, 3734-3746.

883    Isbarn H, Wanner M, Salomon G, Steuber T, Schlomm T, Köllermann J, Sauter G, Haese A,
Heinzer H, Huland H, Graefen M. Long-term data on the survival of patients with prostate cancer treated with radical prostatectomy in the prostate-specific antigen era. BJU Int, 2010 Jul;106(1):37-43

882    Iskar M, Campillos M, Kuhn M, Jensen LJ, van Noort V, Bork P. Drug-induced regulation of target expression.PLoS Comput Biol.  2010 Sep 9;6(9). pii: e1000925.

881    Jacobsen M, Repsilber D, Kleinsteuber K, Gutschmidt A, Schommer-Leitner S, Black G, Walzl G, Kaufmann SH. Suppressor of cytokine signaling (SOCS)-3 is affected in T cells from TB patients. Clin Microbiol Infect. 2010 Jul 29.

880    Jeon J, Dencker D, Wörtwein G, Woldbye DPD, Cui Y, Davis AA, Levey AI, Schütz G, Sager TN, Mork A, Li C, Deng C-X, Fink-Jensen A, Wess J. A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors. J Neurosci. 2010; 30:2396-2405.

879    Jöcker A, Sonntag J, Henjes F, Goetschel F, Tresch A, Beißbarth T, Wiemann S, Korf U. QuantProReloaded: Quantitative Analysis of Microspot Immunoassays. Bioinformatics, 2010, 26(19):2480-1.

878    Johannes M, Brase JC, Fröhlich H, Gade S, Gehrmann M, Fälth M, Sültmann H, Beissbarth T. Integration of pathway knowledge into a reweighted recursive feature elimination approach for risk stratification of cancer patients.  Bioinformatics. 2010; 26(17):2136-44.

877    Joutel A; Monet-Lepretre M; Gosele C; Baron-Menguy C; Hammes A; Schmidt S; Lemaire-Carrette B; Domenga V; Schedl A; Lacombe P; Huebner N. Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease. Journal of Clinical Investigation 120 (2): 433-445 (2010)

876    Jung K, Grade M, Gaedcke J, Jo P, Opitz L, Becker H, Ghadimi BM, Beissbarth T. A new sensitivity-preferred strategy to build prediction rules for therapy response of cancer patients using gene expression data. Comput Methods Programs Biomed. 2010 Apr 9.

875    Jungersted JM, Scheer H, Mempel M, Baurecht H, Cifuentes L, Høgh JK, Hellgren LI, Jemec GB, Agner T, Weidinger S. Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema. Allergy. 2010 Feb 4

874    Juran BD, Atkinson EJ, Schlicht EM, Larson JJ, Ellinghaus D, Franke A,Lazaridis KN. Genetic polymorphisms of matrix metalloproteinase 3 in primary sclerosing cholangitis. Liver Int. 2010 Dec 7. doi: 10.1111/j.1478-3231.2010.02420.x. [Epub ahead of print] PubMed PMID: 21134112.

873    Jürchott K, Kuban RJ, Krech T, Blüthgen N, Stein U, Walther W, Friese C, Kie?basa SM, Ungethüm U, Lund P, Knösel T, Kemmner W, Morkel M, Fritzmann J, Schlag PM, Birchmeier W, Krueger T, Sperling S, Sers C, Royer HD, Herzel H, Schäfer R. Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells. PLoS Genet. 2010 Dec 2;6(12):e1001231.

872    Kamp, F., Exner, N, Lutz, A.K., Wender, N., Hegermann, J., Brunner, B., Nuscher, B., Bartels, T., Giese, A., Beyer, K., Eimer, S., Winklhofer, K.F., and Haass, C. Inhibition of Mitochondrial Fusion by a-Synuclein is rescued by PINK1, Parkin, and DJ-1. EMBO J, 29, 3571-3589.

871    Kam-Thong T, Czamara D, Tsuda K, Borgwardt K, Lewis CM, Erhardt-Lehmann A, Hemmer B, Rieckmann P, Daake M, Weber F, Wolf C, Ziegler A, Pütz B, Holsboer F, Schölkopf B, Müller-Myhsok B. EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units. Eur J Hum Genet. 2011 Apr;19(4):465-71. Epub 2010 Dec 8. doi:10.1038/ejhg.2010.196

870    Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P, Stiehl A, Vermeire S, Beuers U, Manns MP, Schrumpf E, Boberg KM, Schreiber S. Genome-wide association analysis in primary sclerosing cholangitis. Gastroenterology. 2010 Mar;138(3):1102-11. Epub 2009 Nov 26.

869    Karlsen TH, Melum E, Franke A. The utility of genome-wide associationstudiesin hepatology. Hepatology. 2010 Jan 28. [Epub ahead of print] PubMed PMID:20232293.

868    Kasten M, Weichert C, Lohmann K, Klein C. Clinical and demographic characteristics of PINK1 mutation carriers ? A meta-analysis. Mov Disord, im Druck.

867    Keller U, von Bubnoff N, Peschel C, Duyster J. Oncologist's/hematologist's view on the roles of pathologists for molecular targeted cancer therapy. J Cell Mol Med. 2010 Feb 16. [Epub ahead of print]

866    Kempf K, Rose B, Illig T, Rathmann W, Strassburger K, Thorand B, Meisinger C, Wichmann HE, Herder C, Vollmert C. "Vaspin (SERPINA12) genotypes and risk of type 2 diabetes: Results from the MONICA/KORA studies." Exp Clin Endocrinol Diabetes. 2010 Mar;118(3):184-9. Epub 2008 Aug 25.

865    Kemter E, Rathkolb B, Bankir L, Schrewe A, Hans W, Landbrecht C, Klaften M, Ivandic B, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Wolf E, Wanke R, Aigner B. Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia. Am J Physiol Renal Physiol 2010 Jun;298(6):F1405-15. Epub 2010 Mar 10. PMID: 20219826

864    Kiefer F, Witt SH, Frank J, Richter A, Treutlein J, Lemenager T, Berner M, Chichon S, Nöthen MN, Batra A, Wodarz N, Zimmermann U, Spanagel R, Wiedemann K, Smolka M, Heinz A, Rietschel M, Mann K. Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk, and treatment response to acamprosate. Pharmacogenomics J

863    Kiefer F. Neurobiologie und Genetik von Suchterkrankungen. Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, Volume 53, Number 4, 284-288, DOI: 10.1007/s00103-010-1031-1.

862    Kielbasa SM, Blüthgen N, Fähling M, Mrowka R. Targetfinder.org: a resource for systematic discovery of transcription factor target genes.Nucleic Acids Res. 2010:W233-8

861    Kielbasa SM, Klein H, Roider HG, Vingron M, Blüthgen N. TransFind--predicting transcriptional regulators for gene sets.Nucleic Acids Res. 2010:W275-80.

860    Kieper N, Holmström K, Ciceri D, Fiesel F, Wolburg H, Ziviani E, Whitworth A, Martins LM, Kahle PJ, Krüger R. Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1. Exp Cell Res (published online 13.01.2010)

859    Kimura M, Müller-Preuss P, Lu A, Wiesner E, Flachskamm C, Wurst W, Holsboer F, Deussing JM. Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep. Mol Psychiatry. 2010 Feb;15(2):154-165.

858    Klär AA, Ballmaier M, Leopold K, Häke I, Schaefer M, Brühl R, Schubert F, Gallinat J. Interaction of hippocampal volume and N-acetylaspartate concentration deficits in schizophrenia: A combined MRI and 1H-MRS study.

857    Klebe S, Thier S, Lorenz D, Nothnagel M, Schreiber S, Klein C, Hagenah J, Kasten M, Berg D, Srulijes K, Gasser T, Deuschl G, Kuhlenbäumer G. LINGO1 is not associated with Parkinson's disease in German patients. Am. J. Med. Genet. B Neuropsychiatr. Genet 153B(6):1173

856    Kleber ME, Renner W, Grammer TB, Linsel-Nitschke P, Boehm BO, Winkelmann BR, Bugert P, Hoffmann MM, März W. Association of the single nucleotide polymorphism rs599839 in the vicinity of the sortilin 1 gene with LDL and triglyceride metabolism, coronary heart disease and myocardial infarction. The Ludwigshafen Risk and Cardiovascular Health Study. Atherosclerosis. 2010 Apr;209(2):492-7. Epub 2009 Oct 2.PMID: 19837406

855    Kleinhammer A., Wurst W, Kühn R. Gene Silencing in Mice with shRNA Vectors. submitted to METHODS IN ENZYMOLOGY, 'Guide to Techniques in Mouse Development'.

854    Kleinschnitz C, Grund H, Wingler K, Armitage ME, Jones E, Mittal M, Barit D, Schwarz T, Geis C, Kraft P, Barthel K, Schuhmann MK, Herrmann AM, Meuth SG, Stoll G, Meurer S, Schrewe A, Becker L, Gailus-Durner V, Fuchs H, Klopstock T, Hrabé de Angelis M, Jandeleit-Dahm K, Shah AM, Weissmann N, Schmidt HH. Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration. PLoS Biol. 8(9): e1000479. doi:10.1371/journal.pbio.1000479

853    Klinkenberg M, Thurow N, Gispert S, Ricciardi F, Eich F, Prehn JH, Auburger G, Kögel D. Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress. Neuroscience. 2010 Mar 17;166(2):422-34.

852    Klüter, S., C. Grütter, M. Rabiller, V. Pawar, M. Getlik, J.R. Simard, D. Rauh. Structure-based development of a displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem, 2010, 53(1):357-67

851    Klüter, S., J.R. Simard, H. Rode, C. Grütter, V. Pawar, H.C.A. Raaijmakers, T.A. Barf, M. Rabiller, W.A.L. van Otterlo, D. Rauh. Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance, Chem BioChem, 2010, 11(18):2557-6

850    Knöll R, Kostin S, Klede S, Savvatis K, Klinge L, Stehle I, Gunkel S, Kotter S, Babicz K, Sohns M, Miocic S, Didie M, Knöll G, Zimmermann WH, Thelen P, Bickeboller H, Maier L, Schaper W, Schaper J, Kraft T, Tschope C, Linke WA, Chien KR. A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy. Circ Res. 2010;106(4):695-704

849    Kohli MA, Salyakina D, Pfennig A, Lucae S, Horstmann S, Menke A, Kloiber S, Hennings J, Bradley BB, Ressler KJ, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Arch Gen Psychiatry. 2010 Apr;67(4):348-59. doi:10.1001/archgenpsychiatry.2009.201

848    Kohlmann A, Bullinger L, Thiede C, Schaich M, Schnittger S, Döhner K, Dugas M, Klein HU, Döhner H, Ehninger G, Haferlach T. Gene expression profiling in AML with normal karyotype can predict mutations for molecular markers and allows novel insights into perturbed biological pathways. Leukemia. 2010 Apr;24(4):798-805.

847    Konopka W, Kiryk A, Novak M, Herwerth M, Rodriguez Parkitna J, Wawrzyniak M, Kowarsch A, Michaluk P, Dzwonek J, Arnsperger T, Wilczynski G, Merkenschlager M, Theis FJ, Köhr G, Kaczmarek L, Schütz G. miRNA loss enhances learning and memory in mice. J Neurosci 2010; 30:14835-14842.

846    Konrad K, Dempfle A, Friedel S, Heiser P, Holtkamp K, Walitza S, Sauer S,Warnke A, Remschmidt H, Gilsbach S, Schäfer H, Hinney A, Hebebrand J,Herpertz-Dahlmann B. Familiality and molecular genetics of attention networks in ADHD. Am J Med Genet B Neuropsychiatr Genet. 2010 Jan 5;153B(1):148-58.

845    Köttgen A, Pattaro C, Böger CA, Fuchsberger C, Olden M, Glazer NL, Parsa A, Gao X, Yang Q, Smith AV, O'Connell JR, Li M, Schmidt H, Tanaka T, Isaacs A, Ketkar S, Hwang SJ, Johnson AD, Dehghan A, Teumer A, Paré G, Atkinson EJ, Zeller T, Lohman K, Cornelis MC, Probst-Hensch NM, Kronenberg F, Tönjes A, Hayward C, Aspelund T, Eiriksdottir G, Launer LJ, Harris TB, Rampersaud E, Mitchell BD, Arking DE, Boerwinkle E, Struchalin M, Cavalieri M, Singleton A, Giallauria F, Metter J, de Boer IH, Haritunians T, Lumley T, Siscovick D, Psaty BM, Zillikens MC, Oostra BA, Feitosa M, Province M, de Andrade M, Turner ST, Schillert A, Ziegler A, Wild PS, Schnabel RB, Wilde S, Munzel TF, Leak TS, Illig T, Klopp N, Meisinger C, Wichmann HE, Koenig W, Zgaga L, Zemunik T, Kolcic I, Minelli C, Hu FB, Johansson A, Igl W, Zaboli G, Wild SH, Wright AF, Campbell H, Ellinghaus D, Schreiber S, Aulchenko YS, Felix JF, Rivadeneira F, Uitterlinden AG, Hofman A, Imboden M, Nitsch D, Brandstätter A, Kollerits B, Kedenko L, Mägi R, Stumvoll M, Kovacs P, Boban M, Campbell S, Endlich K, Völzke H, Kroemer HK, Nauck M, Völker U, Polasek O, Vitart V, Badola S, Parker AN, Ridker PM, Kardia SL, Blankenberg S, Liu Y, Curhan GC, Franke A, Rochat T, Paulweber B, Prokopenko I, Wang W, Gudnason V, Shuldiner AR, Coresh J, Schmidt R, Ferrucci L, Shlipak MG, van Duijn CM, Borecki I, Krämer BK, Rudan I, Gyllensten U, Wilson JF, Witteman JC, Pramstaller PP, Rettig R, Hastie N, Chasman DI, Kao WH, Heid IM, Fox CS. New loci associated with kidney function and chronic kidney disease. Nat Genet 2010;42:376-84.

844    Kox C, Zimmermann M, Stanulla M, Leible S, Schrappe M, Ludwig WD, Koehler R, Tolle G, Bandapalli OR, Breit S, Muckenthaler MU, Kulozik AE. The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function. Leukemia 2010, 24(12):2005-2013

843    Kramer M, Backhaus O, Rosenstiel P, Horn D, Klopocki E, Birkenmeier G, Schreiber S, Platzer M, Hampe J, Huse K. Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing. Gene. 2010 Feb 4. [Epub ahead of print]

842    Kramer M, Huse K, Menzel U, Backhaus O, Rosenstiel P, Schreiber S, Hampe J, Platzer M. Constant Splice Isoform Ratios in Human Lymphoblastoid Cells Support the Concept of a Splico-Stat. Genetics. 2011 Jan 10. [Epub ahead of print]

841    Kraus JM, Kestler HA. A highly effcient multi-core algorithm for clustering extremely large datasets. BMC Bioinformatics, 11(1):169, 2010.

840    Krebiehl G, Ruckerbauer S, Burbulla L, Kieper N, Maurer B, Waak J, Wolburg H, Gizatullina Z, Gellerich F, Woitalla D, Riess O, Kahle PJ, Proikas-Cezanne T, Krüger R. Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson?s disease-associated protein DJ-1. PLoS One 5: e9367

839    Krug A, Nieratschker V, Markov V, Krach S, Jansen A, Zerres K, Eggermann T, Stöcker T, Shah NJ, Treutlein J, Mühleisen TW, Kircher T. Effect of CACNA1C rs1006737 on neural correlates of verbal fluency in healthy individuals. Neuroimage 49:1831-1836. doi:10.1016/j.neuroimage.2009.09.028

838    Kuenzel S, Till A, Winkler M, Häsler R, Lipinski S, Jung S, Grötzinger J, Fickenscher H, Schreiber S, Rosenstiel P. The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses. J Immunol. 2010 Feb 15;184(4):1990-2000.

837    Kühn, S.; Schubert, F.; Gallinat, J. Reduced thickness in medial orbitofrontal cortex in smokers. Biological Psychiatry, 2010 Sept 25 (Epub ahead of print)

836    Kuffner, R., T. Petri, L. Windhager, R. Zimmer. Petri Nets with Fuzzy Logic (PNFL): reverse engineering and parametrization.' PLoS One 5(9): e12807.

835    Kurz A, Double KL, Lastres-Becker I, Tozzi A, Tantucci M, Bockhart V, Bonin M, García-Arencibia M, Nuber S, Schlaudraff F, Liss B, Fernández-Ruiz  J, Gerlach M, Wüllner U, Lüddens H, Calabresi P, Auburger G, Gispert S. A53T-alpha-Synuclein Overexpression Impairs Dopamine Signaling and Striatal Synaptic Plasticity in Old Mice. 2010 PLoS One. 5(7):1-15. doi:10.1371/journal.pone.0011464

834    Kurz A, Wöhr M, Walter M, Bonin M, Auburger G, Gispert S, Schwarting RK. Alpha-synuclein deficiency affects brain Foxp1 expression and ultrasonic vocalization.Neuroscience. 2010 Mar 31;166(3):785-95.

833    Lacroix J, Leuchs B, Li J, Hristov G, Deubzer HE, Kulozik AE, Rommelaere J, Schlehofer JR, Witt O. Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells. Int J Cancer. 2010 Sep 1;127(5):1230-9.

832    Lamina C, Küchenhoff H, Chang-Claude J, Paulweber B, Wichmann H-E, Illig T, Hoehe MR, Kronenberg F, Heid IM. Haplotype misclassification from genotype error and statistical reconstruction and its impact on association estimates. Annals of Human Genetics, Volume 74, Issue 5, pages 452–462, September 2010

831    Lango Allen H, Estrada K, Lettre G, Berndt S, Weedon MN, Rivadeneira F, Willer CJ, Jackson AU, Vedantam S, Raychaudhuri S, Ferreira T, Wood AR, Weyant RJ, Segrè AV, Speliotes EK, Wheeler E, Soranzo N, Park J-H, Yang J, Gudbjartsson D, Heard-Costa NL, Randall JC, Qi L, Smith AV, Mägi R, Pastinen T, Liang L, Heid IM, Luan Ja, Thorleifsson G, Winkler TW, Goddard ME, Lo KS, Palmer C, Workalemahu T, Aulchenko YS, Johansson Å, Zillikens MC, Feitosa MF, Esko T, Johnson T, Ketkar S, Kraft P, Mangino M, Prokopenko I, Absher D, Albrecht E, Ernst F, Glazer NL, Hayward C, Hottenga J-J, Jacobs KB, Knowles JW, Kutalik Z, Monda KL, Polasek O, Preuss M, Rayner NW, Robertson NR, Steinthorsdottir V, Tyrer JP, Voight BF, Wiklund F, Xu J, Zhao JH, Nyholt DR, Pellikka N, Perola M, Perry JRB, Surakka I, Tammesoo M-L, Altmaier EL, Amin N, Aspelund T, Bhangale T, Boucher G, Chasman DI, Chen C, Coin L, Cooper MN, Dixon AL, Gibson Q, Grundberg E, Hao K, Junttila MJ, Kaplan LM, Kettunen J, König IR, Kwan T, Lawrence RW, Levinson DF, Lorentzon M, McKnight B, Morris AP, Müller M, Ngwa JS, Purcell S, Rafelt S, Salem RM, Salvi E, Sanna S, Shi JS, Ulla, Thompson JR, Turchin MC, Vandenput L, Verlaan DJ, Vitart V, White CC, Ziegler A, Almgren P, Balmforth AJ, Campbell H, Citterio L, De Grandi A, Dominiczak A, Duan J, Elliott P, Elosua R, Eriksson JG, Freimer NB, Geus EJC, Glorioso N, Haiqing S, Hartikainen A-L, Havulinna AS, Hicks AA, Hui J, Igl W, Illig T, Jula A, Kajantie E, Kilpeläinen TO, Koiranen M, Kolcic I, Koskinen S, Kovacs P, Laitinen J, Liu J, Lokki M-L, Marusic A, Maschio A, Meitinger T, Mulas A, Paré G, Parker AN, Peden JF, Petersmann A, Pichler I, Pietiläinen KH, Pouta A, Ridderstråle M, Rotter JI, Sambrook JG, Sanders AR, Schmidt CO, Sinisalo J, Smit JH, Stringham HM, Walters GB, Widen E, Wild SH, Willemsen G, Zagato L, Zgaga L, Zitting P, Alavere H, Farrall M, McArdle WL, Nelis M, Peters MJ, Ripatti S, van Meurs JBJ, Aben KK, Ardlie KG, Beckmann JS, Beilby JP, Bergman RN, Bergmann S, Collins FS, Cusi D, den Heijer M, Eiriksdottir G, Gejman PV, Hall AS, Hamsten A, Huikuri HV, Iribarren C, Kähönen M, Kaprio J, Kathiresan S, Kiemeney L, Kocher T, Launer LJ, Lehtimäki T, Melander O, Mosley Jr TH, Musk AW, Nieminen MS, O'Donnell CJ, Ohlsson C, Oostra B, Palmer LJ, Raitakari O, Ridker PM, Rioux JD, Rissanen A, Rivolta C, Schunkert H, Shuldiner AR, Siscovick DS, Stumvoll M, Tönjes A, Tuomilehto J, van Ommen G-J, Viikari J, Heath AC, Martin NG, Montgomery GW, Province MA, Kayser M, Arnold AM, Atwood LD, Boerwinkle E, Chanock SJ, Deloukas P, Gieger C, Grönberg H, Hall P, Hattersley AT, Hengstenberg C, Hoffman W, Lathrop GM, Salomaa V, Schreiber S, Uda M, Waterworth D, Wright AF, Assimes TL, Barroso I, Hofman A, Mohlke KL, Boomsma DI, Caulfield MJ, Cupples LA, Erdmann J, Fox CS, Gudnason V, Gyllensten U, Harris TB, Hayes RB, Jarvelin M-R, Mooser V, Munroe PB, Ouwehand WH, Penninx BW, Pramstaller PP, Quertermous T, Rudan I, Samani NJ, Spector TD, Völzke H, Watkins HoboPC, Wilson JF, Groop LC, Haritunians T, Hu FB, Kaplan RC, Metspalu A, North KE, Schlessinger D, Wareham NJ, Hunter DJ, O'Connell JR, Strachan DP, Wichmann H-E, Borecki IB, van Duijn CM, Schadt EE, Thorsteinsdottir U, Peltonen L, Uitterlinden A, Visscher PM, Chatterjee N, Loos RJF, Boehnke M, McCarthy MI, Ingelsson E, Lindgren CM, Abecasis GR, Stefansson K, Frayling TM, Hirschhorn JN, for the GIANT Consortium. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 467: 832-8

830    Lascorz J, Försti A, Chen B, Buch S, Steinke V, Rahner N, Holinski-Feder E, Morak M, Schackert HK, Görgens H, Schulmann K, Goecke T, Kloor M, Engel C, Büttner R, Kunkel N, Weires M, Hoffmeister M, Pardini B, Naccarati A, Vodickova L, Novotny J, Schreiber S, Krawczak M, Bröring CD, Völzke H, Schafmayer C, Vodicka P, Chang-Claude J, Brenner H, Burwinkel B, Propping P, Hampe J, Hemminki K. Chromosomal damage in peripheral blood lymphocytes of newly diagnosed cancer patients and healthy controls. Carcinogenesis 31(7): 1238-1241

829    Laws SM, Eckart K, Friedrich P, Eisele T, Kurz A, Förstl H, Riemenschneider M. No association of lipase C polymorphisms with Alzheimer´s disease. Neurobiol Aging. 2010;31(12):2192-3. [Epub ahead of print 2009]

828    Le Hellard S*, Mühleisen TW*, Djurovic S, Ferno J, Ouriaghi Z, Mattheisen M, Vasilescu C, Raeder MB, Hansen T, Strohmaier J, Georgi A, Brockschmidt FF, Melle I, Nenadic I, Sauer H, Rietschel M, Nöthen MM, Werge T, Andreassen OA, Cichon S*, Steen VM* (2010)  *Authors contributed equally. Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian (SCOPE) samples. Molecular Psychiatry 15:463-472. doi:10.1038/mp.2008.110

827    Lehnart SE, Lederer WJ. An antidote for calcium leak: targeting molecular arrhythmia mechanisms. J Mol Cell Cardiol. 2010 Feb;48(2):279-82. Epub 2009 Nov 26. PMID: 19931542

826    Lewis, N., Schramm, G., Bordbar, A.,Schellenberger, J., Andersen, M., Cheng, J., Patel, M., Yee, A., Lewis, R., Eils, R., König, R., Palsson, B. Formulating multi-cellular models of metabolism in tissues: application to energy metabolism in the human brain, Nat. Biotechnology, 28, 1279

825    Lewis, N.E., Hixson, K.K., Conrad, T.M., Lerman, A.J., Charusanti, P., Polpitiya, A.D., Adkins, J.N., Schramm, G., Purvine, S.O., Lopez-Ferrer, D., Weitz, K.K., Eils, R., König, R., Smith, R.D. & Palsson, B.O. Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models, Mol Sys Biol, 6, 390

824    Liao Y, Anttonen AK, Liukkonen E, Gaily E, Maljevic S, Schubert S, Bellan-Koch A, Petrou S, Ahonen VE, Lerche H, Lehesjoki AE. SCN2A mutation associated with neonatal epilepsy, late-onset episodic ataxia, myoclonus and pain. Neurology 2010;75:1454-8.

823    Liao Y, Deprez L, Maljevic S, Pitsch J, Claes L, Hristova D, Jordanova A, Ala-Mello S, Bellan-Koch A, Blazevic D, Schubert S, Thomas EA, Petrou S, Becker AJ, De Jonghe P, Lerche H. Molecular correlates of age-dependent seizures in inherited neonatal-infantile epilepsy. Brain. 2010; 133:1403-1414

822    Lin Z, Nelson L, Franke A, Poritz L, Li TY, Wu R, Wang Y, MacNeill C, Thomas NJ, Schreiber S, Koltun WA. OCTN1 variant L503F is associated with familial and sporadic inflammatory bowel disease. J Crohns Colitis 2010;4:132-8

821    Lin Z, Poritz L, Franke A, Li TY, Ruether A, Byrnes KA, Wang Y, Gebhard AW, MacNeill C, Thomas NJ, Schreiber S, Koltun WA. Genetic association of nonsynonymous variants of the IL23R with familial and sporadic inflammatory bowel disease in women. . Dig Dis Sci. 2010 Mar;55(3):739-46. Epub 2009 Mar 18.

820    Lindner I, Hemdan NY, Buchold M, Huse K, Bigl M, Oerlecke I, Ricken A, Gaunitz F, Sack U, Naumann A, Hollborn M, Thal D, Gebhardt R, Birkenmeier G. Alpha2-macroglobulin inhibits the malignant properties of astrocytoma cells by impeding beta-catenin signaling. Cancer Res. 2010, 70:277.

819    Linsel-Nitschke P, Heeren J, Aherrahrou Z, Bruse P, Gieger C, Illig T, Prokisch H, Heim K, Doering A, Peters A, Meitinger T, Wichmann HE, Hinney A, Reinehr T, Roth C, Ortlepp JR, Soufi M, Sattler AM, Schaefer J, Stark K, Hengstenberg C, Schaefer A, Schreiber S, Kronenberg F, Samani NJ, Schunkert H, Erdmann J. Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease. Atherosclerosis. 2010 Jan;208(1):183-9. Epub 2009 Jul 8.PMID: 19660754

818    Linsel-Nitschke P, Samani NJ, Schunkert H. Sorting out cholesterol and coronary artery disease. N Engl J Med. 2010 Dec 16;363(25):2462-3. PMID: 21158662

817    Linsel-Nitschke P, Schunkert H. Chromosome 9p21 and coronary risk-the mystery continues. Atherosclerosis. 2011 Feb;214(2):257-8. Epub 2010 Sep 21. No abstract available.PMID: 2114682

816    Liss B, Roeper J. A new tool for your novelty centre. J Physiol. 2010 Jun 15; 588(Pt 12):2013. doi:10.1113/jphysiol.2010.192203

815    Liu HK, Wang Y, Belz T, Bock D, Takacs A, Radlwimmer B, Barbus S, Reifenberger G, Lichter P, Schütz G. The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation. Genes Dev. 2010 Apr 1;24(7):683-95.

814    Liu JZ, Tozzi F, Waterworth DM, Pillai SG, Muglia P, Middleton L, BerrettiniW, Knouff CW, Yuan X, Waeber G, Vollenweider P, Preisig M, Wareham NJ, Zhao JH, Loos RJ, Barroso I, Khaw KT, Grundy S, Barter P, Mahley R, Kesaniemi A, McPherson R, Vincent JB, Strauss J, Kennedy JL, Farmer A, McGuffin P, Day R, Matthews K, Bakke P, Gulsvik A, Lucae S, Ising M, Brueckl T, Horstmann S, Wichmann HE, Rawal R, Dahmen N, Lamina C, Polasek O, Zgaga L, Huffman J, Campbell S, Kooner J, Chambers JC, Burnett MS, Devaney JM, Pichard AD, Kent KM, Satler L, Lindsay JM,Waksman R, Epstein S, Wilson JF, Wild SH, Campbell H, Vitart V, Reilly MP, Li M, Qu L, Wilensky R, Matthai W, Hakonarson HH, Rader DJ, Franke A, Wittig M, Schäfer A, Uda M, Terracciano A, Xiao X, Busonero F, Scheet P, Schlessinger D, St Clair D, Rujescu D, Abecasis GR, Grabe HJ, Teumer A, Völzke H, Petersmann A, John U, Rudan I, Hayward C, Wright AF, Kolcic I, Wright BJ, Thompson JR, Balmforth AJ, Hall AS, Samani NJ, Anderson CA, Ahmad T, Mathew CG, Parkes M, Satsangi J, Caulfield M, Munroe PB, Farrall M, Dominiczak A, Worthington J, Thomson W, Eyre S, Barton A; Wellcome Trust Case Control Consortium, Mooser V, Francks C, Marchini J. Meta- analysis and imputation refines the association of 15q25 withsmoking quantity. Nat Genet. 2010 May;42(5):436-40. Epub 2010 Apr 25. PubMed PMID: 20418889.

813    Liu Y, Thilo F, Kreutz R, Schulz A, Wendt N, Loddenkemper C, Jankowski V, Tepel M. Tissue expression of TRPC3 and TRPC6 in hypertensive Munich Wistar Frömter rats showing proteinuria.. Am J Nephrol. 2010;31(1):36-44. Epub 2009 Oct 30

812    Liviu Aron, Pontus Klein, Trang T. Pham, Edgar R. Kramer,Wolfgang Wurst, Rüdiger Klein. Pro-survival role for Parkinson?s associated gene DJ-1 revealed in trophically impaired dopaminergic neurons. PLOS Biol. 2010 Apr 6;8(4):e1000349.

811    Lottaz C, Beier D, Meyer K, Kumar P, Hermann A, Schwarz J, Junker M, Oefner PJ, Bogdahn U, Wischhusen J, Spang R, Storch A, Beier CP. Transcriptional profiles of CD133+ and CD133- glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer Res. 2010 Mar 1;70(5):2030-40. Epub 2010 Feb 9. PubMed PMID: 20145155.

810    Luber CA; Cox J; Lauterbach H; Fancke B; Selbach M; Tschopp J; Akira S; Wiegand M; Hochrein H; O'Keeffe M; Mann M. Quantitative proteomics reveals subset-specific viral recognition in dendritic cells Immunity 32 (2): 279-289 (2010-02-26)

809    Lucae S, Ising M, Horstmann S, Baune BT, Arolt V, Müller-Myhsok B, Holsboer F, Domschke K. HTR2A gene variation is involved in antidepressant treatmentresponse. Eur Neuropsychopharmacol. 2010 Jan;20(1):65-8. doi:10.1016/j.euroneuro.2009.08.006

808    Lücking CB, Lichtner P, Kramer ER, Gieger C, Illig T, Dichgans M, Berg D, Gasser T. Polymorphisms in the receptor for GDNF (RET) are not associated with Parkinson's disease in Southern Germany. Neurobiol. Aging 31(1):167-168.

807    Luedde M, Ehlermann P, Weichenhan D, Will R, Zeller R, Rupp S, Muller A, Steen H, Ivandic BT, Ulmer HE, Kern M, Katus HA, Frey N. Severe familial left ventricular non-compaction cardiomyopathy due to a novel troponin T (TNNT2) mutation. (2010) Cardiovasc Res 86(3):452-60.

806    Lunshof JE, Bobe J, Aach J, Angrist M, Thakuria JV, Vorhaus DB, Hoehe MR, Church GM. Personal genomes in progress: from the human genome project to the personal genome project. Dialogues Clin Neurosci. 2010;12(1):47-60

805    Ma, L., J. Young, H. Prabhala, E. Pan, P. Mestdagh, D. Muth, J. Teruya-Feldstein, F. Reinhardt, T.T. Onder, S. Valastyan, F. Westermann, F. Speleman, J. Vandesompele, and R.A. Weinberg. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nat Cell Biol, 2010. 12(3): p. 247-56. IF 17.623.

804    Machner B, Klein C, Sprenger A, Baumbach P, Pramstaller P, Helmchen C, Heide W. Eye movement disorders are different in Parkin-linked and idiopathic early-onset Parkinson?s disease. Neurology, im Druck.

803    Maetzler W, Stoycheva V, Schmid B, Schulte C, Hauser A, Brockmann K, Melms A, Gasser T, Berg D. Neprilysin activity in cerebrospinal fluid is associated with dementia and amyloid-?42 levels in Lewy body disease. J. Alzheimers Dis 22(3):933-938.

802    Mai S, Klinkenberg M, Auburger G, Bereiter-Hahn J, Jendrach M. Decreased expression of Drp1 and Fis1 mediates mitochondrial elongation in senescent cells and enhances resistance to oxidative stress through PINK1. J Cell Sci. 2010 Mar 15;123(Pt 6):917-26.

801    Malinowsky K, Böllner C, Hipp S, Berg D, Schmitt M, Becker KF. UPA and PAI-1 Analysis from Fixed Tissues - New Perspectives for a Known Set of Predictive Markers. Curr Med Chem. 2010 Oct 13. [Epub ahead of print]

800    Malinowsky K, Wolff C, Ergin B, Berg D, Becker KF. Deciphering signaling pathways in clinical tissues for personalized medicine using protein microarrays. J Cell Physiol. 2010 Nov;225(2):364-70

799    Maljevic S, Wuttke TV, Seebohm G, Lerche H. KV7 channelopathies. Pflugers Arch. 2010 Jul;460(2):277-88. Epub 2010 Apr 18.

798    Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stühler K, Meyer HE, Reifenberger G. Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas. Brain Pathol. 2010 May;20(3):539-50.

797    Manke T, Heinig M, Vingron M. Quantifying the effect of sequence variation on regulatory interactions.Hum Mutat. 2010 Feb 2.

796    Mannsperger HA, Uhlmann S, Schmidt C, Wiemann S, Sahin O, Korf U RNAi-based validation of antibodies for reverse phase protein arrays. Proteome Sci 8: 69.

795    Markova B, Albers C, Breitenbuecher F, Melo JV, Brümmendorf TH, Heidel F, Lipka D, Duyster J, Huber C, Fischer T. Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-gamma1-driven activation of mTOR/p70S6-kinase pathway. Oncogene. 2010 Feb 4;29(5):739-51.

794    Marmé F, Werft W, Benner A, Burwinkel B, Sinn P, Sohn C, Lichter P, Hahn M, Schneeweiss A. FGFR4 Arg388 genotype is associated with pathological complete response to neoadjuvant chemotherapy for primary breast cancer. Ann Oncol. 2010 Feb 10. [Epub ahead of print]PMID: 20147743 [PubMed - as supplied by publisher]Related articles

793    Marschalek R. Mixed lineage leukemias: roles in human malignancies and potential therapy. FEBS J 277:1822-1831.

792    Marzi C, Albrecht E, Hysi PG, Lagou V, Waldenberger M, Tönjes A, Prokopenko I, Heim K, Blackburn H, Ried JS, Kleber ME, Mangino M, Thorand B, Peters A, Hammond CJ, Grallert H, Boehm BO, Kovacs P, Geistlinger L, Prokisch H, Winkelmann BR, Spector TD, Wichmann HE, Stumvoll M, Soranzo N, März W, Koenig W, Illig T, Gieger C. Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A. PLoS Genet 2010;6:e1001213.

791    Mathias RA, Grant AV, Rafaels N, Hand T, Gao L, Vergara C, Tsai YJ, Yang M,Campbell M, Foster C, Gao P, Togias A, Hansel NN, Diette G, Adkinson NF, Liu MC, Faruque M, Dunston GM, Watson HR, Bracken MB, Hoh J, Maul P, Maul T, Jedlicka AE, Murray T, Hetmanski JB, Ashworth R, Ongaco CM, Hetrick KN, Doheny KF, Pugh EW, Rotimi CN, Ford J, Eng C, Burchard EG, Sleiman PM, Hakonarson H, Forno E, Raby BA, Weiss ST, Scott AF, Kabesch M, Liang L, Abecasis G, Moffatt MF, Cookson WO, Ruczinski I, Beaty TH, Barnes KC. A genome-wide association study on African-ancestry populations for asthma. J Allergy Clin Immunol. 2010 Feb;125(2):336-346.e4. Epub 2009 Nov 11. PubMed PMID: 19910028.

790    Mathieu F, Dizier MH, Etain B, Jamain S, Rietschel M, Maier W, Albus M, McKeon P, Roche S, Blackwood D, Muir WJ, Henry C, Malafosse A, Preisig M, Ferrero F, Cichon S, Schumacher J, Ohlraun S, Propping P, Abou Jamra R, Schulze TG, Zelenica D, Charon C, Marusic A, Dernovsek MC, Gurling H, Nöthen M, Lathrop M, Leboyer M, Bellivier F. European collaborative study of early-onset bipolar disorder: Evidence for genetic heterogeneity on 2q14 according to age at onset. Am J Med Genet B Neuropsychiatr Genet. 2010 Dec 5;153B(8):1425-33. doi: 10.1002/ajmg.b.31121. Epub 2010 Sep 30.

789    Maucher M, Schöning U, Kestler HA. Search heuristics and the influence of non-perfect randomness. Comput Stat. 2010;  in press.

788    Mazur PK, Einwächter H, Lee M, Sipos B, Nakhai H, Rad R, Zimber-Strobl U, Strobl LJ, Radtke F, Klöppel G, Schmid RM,  Siveke JT. Notch2 is required for progression of pancreatic intraepithelial neoplasia and development of pancreatic ductal adenocarcinoma. PNAS. 2010;107(30):13438-43.

787    McMahon FJ, Akula N, Schulze TG, Muglia P, Tozzi F, Detera-Wadleigh SD, Steele CJ, Breuer R, Strohmaier J, Wendland JR, Mattheisen M, Mühleisen TW, Maier W, Nöthen MM, Cichon S, Farmer A, Vincent JB, Holsboer F, Preisig M, Rietschel M; Bipolar Disorder Genome Study (BiGS) Consortium. Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.). Nature Genetics 42:128-131. doi:10.1038/ng.523

786    Meder B, Just S, Vogel B, Rudloff J, Gartner L, Dahme T, Huttner I, Zankl A, Katus HA, Rottbauer W. JunB-CBFß Signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure. J Cell Science 2010, in press.

785    Meder B, Keller A, Vogel B, Haas J, Sedaghat F, Kayvanpour E, Just S, Borries A, Rudloff J, Leidinger P, Meese E, Katus HA, Rottbauer W. MicroRNA Signatures in Total Peripheral Blood as Novel Biomarkers for Acute Myocardial Infarction. Basic Res Cardiol. 2010 (online first, DOI 10.1007/s00395-010-0123-2)

784    Meder, B., S. Just, B. Vogel, J. Rudloff, L. Gärtner, T. Dahme, I. Huttner, A. Zankl, H.A. Katus, W. Rottbauer. JunB-CBFß Signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure. JCS in press

783    Melum E, May S, Schilhabel MB, Thomsen I, Karlsen TH, Rosenstiel P, Schreiber S, Franke A. SNP discovery performance of two second-generation sequencingplatforms in the NOD2 gene region. Hum Mutat. 2010 Jul;31(7):875-85. PubMed PMID:20506538

782    Mestdagh P, Fredlund E, Pattyn F, Rihani A, Van Maerken T, Vermeulen J, Kumps C, Menten B, De Preter K, Schramm A, Schulte J, Noguera R, Schleiermacher G, Janoueix-Lerosey I, Laureys G, Powel R, Nittner D, Marine JC, Ringnér M, Speleman F, Vandesompele J. An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours. Oncogene. 2010;29:3583-92.

781    Mestdagh P, Fredlund E, Pattyn F, Schulte JH, Muth D, Vermeulen J, Kumps C, Schlierf S, De Preter K, Van Roy N, Noguera R, Laureys G, Schramm A, Eggert A, Westermann F, Speleman F, Vandesompele J. MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors. Oncogene. 2010;29:1394-404.

780    Meyer CW, Willershäuser M, Jastroch M, Rourke B, Fromme T, Oelkrug R, Heldmaier G, Klingenspor M. Adaptive thermogenesis and thermal conductance in wildtype and UCP1-KO mice. Am J Physiol Regul Integr Comp Physiol. 2010 Nov; 299(5):R1396-406.

779    Meyer L, Hrabé de Angelis M, Wurst W, Kühn R. Gene Targeting by Homologous Recombination in Mouse Oocytes mediated by Zinc-Finger Nucleases. Proc. Natl. Acad. Sci. USA 2010 Aug 24; 107 (34): 15022-6

778    Michaelis M, Kleinschmidt MC, Barth S, Rothweiler F, Geiler J, Breitling R, Mayer B, Deubzer H, Witt O, Kreuter J, Doerr HW, Cinatl J, Cinatl J Jr. Anti-cancer effects of artesunate in a panel of chemoresistant neuroblastoma cell lines. Biochem Pharmacol. 2010 Jan 15;79(2):130-6. Epub 2009 Aug 19.

777    Michel S, Liang L, Depner M, Klopp N, Ruether A, Kumar A, Schedel M, Vogelberg C, von Mutius E, von Berg A, Bufe A, Rietschel E, Heinzmann A, Laub O, Simma B, Frischer T, Genuneit J, Gut IG, Schreiber S, Lathrop M, Illig T, Kabesch M. Unifying candidate gene and GWAS Approaches in Asthma. PLoS One. 2010 Nov 12;5(11):e13894.

776    Milde T, Oehme I, Korshunov A, Kopp-Schneider A, Remke M, Northcott P, Deubzer HE, Lodrini M, Taylor MD, von Deimling A, Pfister S, Witt O. HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth. Clin Cancer Res. 2010 Jun 15;16(12):3240-52. Epub 2010 Apr 22

775    Minner S, Jessen B, Stiedenroth L, Burandt E, Kollermann J, Mirlacher M, Erbersdobler A, Eichelberg C, Fisch M, Brummendorf TH, Bokemeyer C, Simon R, Steuber T, Graefen M, Huland H, Sauter G, Schlomm T. Low level HER2 overexpression is associated with rapid tumor cell proliferation and poor prognosis in prostate cancer. Clin Cancer Res 2010;16:1553-1560.

774    Minner S, Wittmer C, Graefen M, Salomon G, Steuber T, Haese A, Huland H, Bokemeyer C, Yekebas E, Dierlamm J, Balabanov S, Kilic E, Wilczak W, Simon R, Sauter G, Schlomm T. High level PSMA expression is associated with early PSA recurrence in surgically treated prostate cancer. Prostate 2010, in press

773    Mittelstaedt T, Alvaréz-Baron E, Schoch. RIM proteins and their role in synapse function. Biol Chem. 2010 Jun;391(6):599-606. PMID:20370319

772    Mitter D, Delle Chiaie B, Gillessen-Kaesbach G, Bohring A, Kohlhase J, Lüdecke H-J, Caliebe A, Siebert R, Roepke A, Ramos-Arroyo MA, Nieva B, Menten B, Loeys B, Mortier G, Wieczorek D. Genotype-phenotype correlation in the 2q31.1 microdeletion syndrome ? eight new patients. Am J Med Genet A. 2010 May;152A(5):1213-24

771    Mollenhauer B, El-Agnaf OM, Marcus K, Trenkwalder C, Schlossmacher MG. Quantification of ?-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies. Biomark Med. 2010 Oct;4(5):683-99. PMID: 20945981

770    Möller M, Flachsbart F, Till A, Thye T, Horstmann RD, Meyer CG, Osei I, van Helden PD, Hoal EG, Schreiber S, Nebel A, Franke A. A functional haplotype in the 3'untranslated region of TNFRSF1B is associated with tuberculosis in two African populations.Am J Respir Crit Care Med. 2010 Feb 15;181(4):388-93.

769    Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt Weisenhorn V, Van Coster R, Wurst W, Scorrano L, De Strooper B. Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. EMBO Journal of Molecular Medicine. 2009 1(2): 99-111.

768    Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S,  Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J,Wood J, The EUMODIC Consortiumy, Hrabé de Angelis M, Brown SDM,Hancock JM and Mallon A-M. EuroPhenome: a repository for high-throughputmouse phenotyping data. Nucleic Acids Res. 2010 Jan;38 (Database issue):D577-85. doi:10.1093/nar/gkp1007

767    Muhle H, Steinich I, von Spiczak S, Franke A, Weber Y, Lerche H, Wittig M, Heidemann S, Suls A, de Jonghe P, Marini C, Guerrini R, Scheffer IE, Berkovic SF, Stephani U, Siebert R, Sander T, Helbig I, Tönnies H. A duplication in 1q21.3 in a family with early onset and childhood absence epilepsy. Epilepsia. 2010 Dec;51(12):2453-6. doi: 10.1111/j.1528-1167.2010.02712.x. Epub 2010 Sep 24.

766    Muhle H, von Spiczak S, Gaus V, Kara S, Helbig I, Hampe J,  Franke A, Weber Y, Lerche H, Kleefuss-Lie AA, Elger CE, Schreiber S, Stephani U, Sander T. Role of GRM4 in idiopathic generalized epilepsies analysed by genetic association and sequence analysis. Epilepsy Res. 2010 May;89(2-3):319-26. Epub 2010 Mar 24.

765    Muller J, Szklarczyk D, Julien P, Letunic I, Roth A, Kuhn M, Powell S, von Mering C, Doerks T, Jensen LJ, Bork P. eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations. Nucleic Acids Res. 2010 Jan; 38(Database issue):D190-195. doi 10.1093/nar/gkp951

764    Müller TD, Tschöp MH, Jarick I, Ehrlich S, Scherag S, Herpertz-Dahlmann B, Zipfel S, Herzog W, de Zwaan M, Burghardt R, Fleischhaker C, Klampfl K, Wewetzer C, Herpertz S, Zeeck A, Tagay S, Burgmer M, Pfluger PT, Scherag A, Hebebrand J, Hinney A. "Genetic variation of the ghrelin activator gene ghrelin O-acyltransferase (GOAT) is associated with anorexia nervosa." Journal of Psychiatric Research 2010; [Epub ahead of print]

763    Müller, H.; Mirgorodskaya, E.; Steinbrink, S.; Schmidt, D.; Lehmann, V.; Habermann, K.; Gustavsson, N.; Kessler, T.; Ploubidou, A.; Lehrach, H.; Gobom, J.; Boutros, M.; Lange, B.M.H. Proteomic and functional analysis of the Drosophila centrosome. EMBO Journal, 29:3344-3357 (2010)

762    Müller, TD., Brönner, G., Wandolski, M., Carrie, J., Nguyen, T.T., Greene, B.H., Scherag, A., Grallert, H., Vogel, C.I.G., Scherag, S., Rief, W., Wichmann, H.E., Illig, T., Schaefer, H., Hebebrand, J., Hinney, A. "Mutation screen and association studies for the fatty acid amide hydrolase (FAAH) gene and early onset and adult obesity." BMC Med Genet 11:2, 1-9 (2010)

761    Müller-Tidow C, Klein H-U, Hascher A, Isken F, Tickenbrock L, Thoennissen N, Agrawal-Singh S, Tschanter P, Disselhoff C, Wang Y, Becker A, Thiede C, Ehninger G, zur Stadt U, Koschmieder S, Seidl M, Müller FU, Schmitz W, Schlenke P, McClelland M, Berdel WE, Dugas M and Serve H. Profiling of Histone H3 lysine 9 trimethylation levels predicts Transcription Factor Activity and Survival in Acute Myeloid Leukemia. Blood. 2010; 116(18):3564-71.

760    Müssel C, Hopfensitz M, Kestler HA. BoolNet - an R package for generation, reconstruction, and analysis of Boolean networks. Bioinformatics, 26(10):1378?1380, 2010.

759    Muth D, Ghazaryan S, Eckerle I, Beckett E, Pöhler C, Batzler J, Beisel C, Gogolin S, Fischer M, Henrich KO, Ehemann V, Gillespie P, Schwab M, Westermann F. Transcriptional repression of SKP2 is impaired in MYCN-amplified neuroblastoma. Cancer Res, 2010, 70(9):3791-3802.

758    Mutschler J, Bilbao A, von der Goltz C, Demiralay C, Jahn H, Wiedemann K, Spanagel R, Kiefer F. Augmented stress-induced alcohol drinking and withdrawal in mice lacking functional natriuretic peptide A receptors. Alcohol Alcoholism 45:13-6

757    Naeem, H., R. Küffner, G. Csaba and R. Zimmer. miRSel: automated extraction of associations between microRNAs and genes from the biomedical literature.' BMC Bioinformatics. 11: 135.

756    Neumann B, Walter T, Heriche JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wunsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature 464: 721-727.

755    Neuschl C, Hantschel C, Wagener A, Schmitt AO, Illig T, Brockmann GA. A unique genetic defect on chromosome 3 is responsible for juvenile obesity in the Berlin Fat Mouse. Int. J. Obesity. 2010; 34(12):1706-1714

754    Nevo I, Oberthür A, Edri-Botzer L, Sagi-Assif O, Pasmanik-Chor M, Kariv N, Fischer M, Yron I, Witz IP. Gene-expression-based analysis of local and metastatic neuroblastoma variants reveals a set of genes associated with tumor progression in neuroblastoma patients. Int J Cancer, 2010, 126(7):1570-81.

753    Nicodemus KK, Callicott JH, Higier RG, Luna A, Nixon DC, Lipska BK, Vakkalanka R, Giegling I, Rujescu D, Clair DS, Muglia P, Shugart YY, Weinberger DR. Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging. Hum Genet. 2010 Jan 19.

752    Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, Weinberger DR. Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls. Arch Gen Psychiatry. Oct;67(10):991-1001

751    Niehusmann P, Bien CG, Drexler JF, Grote A, Schoch S, Becker AJ. Presence of human herpes virus-6 DNA in temporal lobe epilepsy brain tissue of patients with history of encephalitis but not other pathologies. Epilepsia. 2010; 51(12):2478-2483

750    Nieratschker V, Frank J, Mühleisen TW, Strohmaier J, Wendland JR, Schumacher J, Treutlein J, Breuer R, Abou Jamra R, Mattheisen M, Herms S, Schmäl C, Maier W, Nöthen MM, Cichon S, Rietschel M, Schulze TG. The catechol-O-methyl transferase (COMT) gene and its potential association with schizophrenia: findings from a large German case-control and family-based sample. Schizophr Res. 2010 Sep;122(1-3):24-30. Epub 2010 Jul 19.

749    Nischwitz S, Cepok S, Kroner A, Wolf C, Knop M, Müller-Sarnowski F, Pfister H, Roeske D, Rieckmann P, Hemmer B, Ising M, Uhr M, Bettecken T, Holsboer F, Müller-Myhsok B, Weber F. Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. J Neuroimmunol. 2010 Oct 8;227(1-2):162-6. Epub 2010 Jul 2. doi:10.1016/j.jneuroim.2010.06.003

748    Noori H R, W. Jäger. Neurochemical oscillations in the basal ganglia, Bull. Math. Biol. 2010 Jan 72(1):133-47.

747    Nothnagel M, Lu TT, Kayser M, Krawczak M. Genomic and geographic distribution of SNP-defined runs of homozygosity in Europeans. Hum Mol Genet. 2010 Aug 1;19(15):2927-35. Epub 2010 May 12. PMID: 20462934

746    Novak M, Halbout B, O?Connor EC, Rodriguez Parkitna J, Su T, Chai M, Crombag HS, Bilbao A, Spanagel R, Stephens DN. Incentive learning underlying cocaine relapse requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons. J Neurosci, 30:11973-82 (7.178)

745    Nuber S, Franck T, Wolburg H, Schumann U, Casadei N, Fischer K, Calaminus C, Pichler BJ, Chanarat S, Teismann P, Schulz JB, Luft AR, Tomiuk J, Wilbertz J, Bornemann A, Krüger R, Riess O. Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice. Neurogenetics. 2010 Feb;11(1):107-20.

744    Oberthuer A, Hero B, Berthold F, Juraeva D, Faldum A, Kahlert Y,  Asgharzadeh S, Seeger R, Scaruffi P, Tonini GP, Janoueix-Lerosey I,  Delattre O, Schleiermacher G, Vandesompele J, Vermeulen J, Speleman F, Noguera R, Piqueras M, Benard J, Valent A, Avigad S, Yaniv I, Weber A, Christiansen H, Grundy RG, Schardt K, Schwab M, Eils R, Warnat P, Kaderali L, Simon T, DeCarolis B, Theissen J, Westermann F, Brors B, Fischer M. The prognostic impact of gene expression-based
classification for neuroblastoma J Clin Oncol. 2010 Jul 20;28(21):3506-3515

743    Oberthuer A, Juraeva D, Li L, Kahlert Y, Westermann F, Eils R, Berthold F, Shi L, Wolfinger RD, Fischer M, Brors B. Comparison of performance of one-color and two-color gene-expression analyses in predicting clinical endpoints of neuroblastoma patients. Pharmacogenomics J, 2010, 10:258-266.

742    Oberthuer, A., B. Hero, F. Berthold, D. Juraeva, A. Faldum, Y. Kahlert, S. Asgharzadeh, R. Seeger, P. Scaruffi, G.P. Tonini, I. Janoueix-Lerosey, O. Delattre, G. Schleiermacher, J. Vandesompele, J. Vermeulen, F. Speleman, R. Noguera, M. Piqueras, J. Benard, A. Valent, S. Avigad, I. Yaniv, A. Weber, H. Christiansen, R.G. Grundy, K. Schardt, M. Schwab, R. Eils, P. Warnat, L. Kaderali, T. Simon, B. Decarolis, J. Theissen, F. Westermann, B. Brors, and M. Fischer. Prognostic Impact of Gene Expression-Based Classification for Neuroblastoma. J Clin Oncol, 2010. 28(21): p. 3506-3515.

741    O'Donoghue SI, Gavin AC, Gehlenborg N, Goodsell DS, Heriche JK, Nielsen CB, North C, Olson AJ, Procter JB, Shattuck DW, Walter T, Wong B. Visualizing biological data-now and in the future. Nat Methods 7: S2-4.

740    Ottman R, Hirose S, Jain S, Lerche H, Lopes-Cendes I, Noebels JL, Serratosa J, Zara F, Scheffer IE. Genetic testing in the epilepsies - Report of the ILAE Genetics Commission. Epilepsia 2010 Apr;51(4):655-70. Epub 2010 Jan 19.

739    Park SQ, Kahnt T, Beck A, Cohen MX, Dolan RJ, Wrase J, Heinz A. Prefrontal cortex fails to learn from reward prediction errors in alcohol dependence. J Neurosci. 30(22):7749-53.

738    Parry RM, Jones W, Stokes TH, Phan JH, Moffitt RA, Fang H, Shi L, Oberthuer A, Fischer M, Tong W, Wang MD. k-Nearest neighbor models for microarray gene expression analysis and clinical outcome prediction. Pharmacogenomics J, 2010, 10:292-309.

737    Paschka P, Schlenk R.F, Gaidzik V.I, Habdank M, Krönke J, Bullinger L, Späth D, Kayser S, Zucknick M, Götze K, Horst H-A, Germing U, Döhner H, Döhner K. IDH1 and IDH2 Mutations are Frequent Genetic Alterations in Acute Myeloid Leukemia (AML) and Confer Adverse Prognosis in Cytogenetically Normal AML with NPM1 Mutation without FLT3-ITD. J Clinic Oncol. 2010;Jun 21 [Epub ahead of print].

736    Paszkowski-Rogacz M, Slabicki M, Pisabarro MT, Buchholz F. PhenoFam-gene set enrichment analysis through protein structural information. BMC Bioinformatics. 2010 May 17;11:254.

735    Pawar, V., M. Sos, H. Rode, M. Rabiller, S. Heynck, W. van Otterlo, R. Thomas, D. Rauh. Synthesis and biological evaluation of 4-anilinoquinolines as potent inhibitors of EGFR, J Med Chem, 2010, 53(7):2892-901

734    Pechlivanis S, Scherag A, Mühleisen TW, Möhlenkamp S, Horsthemke B, Boes T, Bröcker-Preuss M, Mann K, Erbel R, Jöckel KH, Nöthen MM, Moebus S; for the Heinz Nixdorf Recall Study Group. Coronary Artery Calcification and Its Relationship to Validated Genetic Variants for Diabetes Mellitus Assessed in the Heinz Nixdorf Recall Cohort. Arterioscler Thromb Vasc Biol. 2010 Jul 8.

733    Peifer M, Weiss J, Sos ML, Koker M, Heynck S, Netzer C, Fischer S, Rode H, Rauh D, Rahnenführer J, Thomas RK. Analysis of compound synergy in high-throughput cellular screens by population-based lifetime modeling. PLoS One. 2010 Jan 27;5(1):e8919

732    Pelz O, Gilsdorf M, Boutros M. web cellHTS: A web-application for the analysis of high-throughput screening data. BMC Bioinformatics. 2010 Apr 12;11(1):185.

731    Perlis RH, Huang J, Purcell S, Fava M, Rush AJ, Sullivan PF, Hamilton SP, McMahon FJ, Schulze T, Potash JB, Zandi PP, Willour VL, Penninx BW, Boomsma DI, Vogelzangs N, Middeldorp CM, Rietschel M, Nöthen M, Cichon S, Gurling H, Bass N, McQuillin A, Hamshere M; Wellcome Trust Case Control Consortium Bipolar Disorder Group, Craddock N, Sklar P, Smoller JW. Genome-wide association study of suicide attempts in mood disorder patients. American Journal of Psychiatry 167:1499-1507. doi: 10.1176/appi.ajp.2010.10040541

730    Perlis RH, Smoller JW, Mysore J, Sun M, Gillis T, Purcell S, Rietschel M, Nöthen MM, Witt S, Maier W, Iosifescu DV, Sullivan P, Rush AJ, Fava M, Breiter H, Macdonald M, Gusella J. Prevalence of incompletely penetrant Huntington's disease alleles among individuals with major depressive disorder. American Journal of Psychiatry 167:574-579. doi: 10.1176/appi.ajp.2009.09070973

729    Perreau-Lenz S, Sanchis-Segura C, Leonardi-Essmann F, Zghoul T, Schneider M,  Spanagel R. Development of morphine-induced tolerance and withdrawal: Involvement of the clock gene mPer2. Eur Neuro

728 Perry JR, Weedon MN, Langenberg C, Jackson AU, Lyssenko V, Sparsø T, Thorleifsson G, Grallert H, Ferrucci L, Maggio M, Paolisso G, Walker M, Palmer CN, Payne F, Young E, Herder C, Narisu N, Morken MA, Bonnycastle LL, Owen KR, Shields B, Knight B, Bennett A, Groves CJ, Ruokonen A, Jarvelin MR, Pearson E, Pascoe L, Ferrannini E, Bornstein SR, Stringham HM, Scott LJ, Kuusisto J, Nilsson P, Neptin M, Gjesing AP, Pisinger C, Lauritzen T, Sandbaek A, Sampson M, Zeggini ME, Lindgren CM, Steinthorsdottir V, Thorsteinsdottir U, Hansen T, Schwarz P, Illig T, Laakso M, Stefansson K, Morris AD, Groop L, Pedersen O, Boehnke M, Barroso I, Wareham NJ, Hattersley AT, McCarthy MI, Frayling TM. "Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes." Hum Mol Genet. 2010 Feb 1;19(3):535-44. Epub 2009 Nov 18.

727 Petry IB, Fieber E, Schmidt M, Gehrmann M, Gebhard S, Hermes H, Schormann W, Selinski S, Freis E, Schwender H, Brulport M, Ickstadt K, Rahnenführer J, Maccoux L, West J, Kölbl H, Schuler M, Hengstler JG. ERBB2 induces an antiapoptotic expression pattern of Bcl-2 family members in node-negative breast cancer. Clin Cancer Res. 2010 Jan 15;16(2):451-60.doi: 10.1158/1078-0432.CCR-09-1617

726 Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, So-toodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Müller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Elli-nor PT, Sanna S, Kääb S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR. Genome-wide association study of PR interval. Nat Genet. 2010 Feb;42(2):153-9. Epub 2010 Jan 10

725 Pham TT, Giesert F, Röthig A, Floss T, Kallnik M, Weindl K, Hölter SM, Ahting U, Prokisch H, Becker L, Klopstock T, Hrabé de Angelis M, Beyer K, Görner K, Kahle PJ, Vogt Weisenhorn DM, and Wurst W. DJ-1-deficient mice show less TH-positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments.Genes Brain Behav. 2010 Apr;9(3):305-17

724 Pinto LA, Depner M, Klopp N, Illig T, Vogelberg C, von Mutius E, Kabesch M. MMP-9 gene variants increase the risk for non-atopic asthma in children. Respir Res. 2010 Feb 24;11:23. PubMed PMID: 20181264;

723 Pinto, L., Efferth, T., Torres, A., Hoheisel, J.D. & Youns, M. Berberine selectively inhibits cell growth and mediates caspase-independent cell death in human pancreatic cancer cells. Planta Med. 76, 1155-1161.

722 Preuss M, König IR, Thompson JR, Erdmann J, Absher D, Assimes TL, Blankenberg S, Boerwinkle E, Chen L, Cupples LA, Hall AS, Halperin E, Hengstenberg C, Holm H, Laaksonen R, Li M, März W, McPherson R, Musunuru K, Nelson CP, Burnett MS, Epstein SE, O'Donnell CJ, Quertermous T, Rader DJ, Roberts R, Schillert A, Stefansson K, Stewart AF, Thorleifsson G, Voight BF, Wells GA, Ziegler A, Kathiresan S, Reilly MP, Samani NJ, Schunkert H; CARDIoGRAM Consortium. Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet. 2010 Oct 1;3(5):475-83

721 Raabe CA, Sanchez CP, Randau G, Robeck T, Skryabin BV, Chinni SV, Kube M, Reinhardt R, Ng GH, Manickam R, Kuryshev VY, Lanzer M, Brosius J, Tang TH, Rozhdestvensky TS. A global view of the non protein-coding transcriptome in Plasmodium falciparum. Nucleic Acids Res 38:608-617. Epub 2009 Oct 28.

720 Rabiller M., M. Getlik, S. Klüter, S. Tückmantel, A. Richters, J.R. Simard, D. Rauh. Proteus in the World of Proteins: Conformational Changes in Protein Kinases, Arch Pharm (Weinheim), 2010, 343(4):193-206

719 Rakovic A, Grünewald A, Seibler P, Ramirez A, Kock N, Orolicki S, Lohmann K, Klein C. Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients. Hum Mol Genet 2010;19:3124-3137.

718 Ramírez F, Albrecht M. Finding scaffold proteins in interactomes. Trends Cell Biol. 2010 Jan;20(1):2-4.

717 Rauh D. Inaktive Kinasekonformationen stabilisieren. Nachrichten aus der Chemie, Gesellschaft Deutscher Chemiker, 2010, 58(2)

716 Rawat VP, Arseni N, Ahmed F, Mulaw MA, Thoene S, Heilmeier B, Sadlon T, D'Andrea RJ, Hiddemann W, Bohlander SK, Buske C, Feuring-Buske M. The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia. Proc Natl Acad Sci U S A. 2010;107:16946-16951

715 Rhein P, Mitlohner R, Basso G, Gaipa G, Dworzak MN, Kirschner-Schwabe R, Hagemeier C, Stanulla M, Schrappe M, Ludwig WD, Karawajew L, Ratei R. CD11b is a therapy-resistance and minimal residual disease-specific marker in precursor B-cell acute lymphoblastic leukemia. Blood. 2010 Mar 12; [Epub ahead of print]. doi 10.1182/blood-2009-10-247585

714 Riehl A, Bauer T, Brors B, Busch H, Mark R, Németh J, Gebhardt C, Bierhaus A, Nawroth P, Eils R, König R, Angel P, Hess J. Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation. BMC Genomics. 2010 Oct 5;11:537.

713 Rietschel M, Mattheisen M, Frank J, Treutlein J, Degenhardt F, Breuer R, Steffens M, Mier D, Esslinger C, Walter H, Kirsch P, Erk S, Schnell K, Herms S, Wichmann HE, Schreiber S, Jöckel KH, Strohmaier J, Roeske D, Haenisch B, Gross M, Hoefels S, Lucae S, Binder EB, Wienker TF, Schulze TG, Schmäl C, Zimmer A, Juraeva D, Brors B, Bettecken T, Meyer-Lindenberg A, Müller-Myhsok B, Maier W, Nöthen MM, Cichon S. Genome-Wide Association-, Replication-, and Neuroimaging Study Implicates HOMER1 in the Etiology of Major Depression. Biol Psychiatry 2010;68(6):578-585.

712 Robubi, A., H. Waldmann, D. Rauh. RAF kinase inhibitors in cancer treatment: like a bull in a china shop?, ChemBioChem, 2010, 11(12):1645-8

711 Rodriguez Parkitna J, Bilbao A, Rieker C, Engblom D, Peichota M, Nordheim A, Spanagel R*, Schütz G*. Loss of the Serum Response Factor in the dopamine system leads to hyperactivity. FASEB J Mar 11 [Epub ahead of print]

710 Romanowski CP, Fenzl T, Flachskamm C, Wurst W, Holsboer F, Deussing JM, Kimura M. Central deficiency of corticotropin-releasing hormone receptor type 1 (CRH-R1) abolishes effects of CRH on NREM but not on REM sleep in mice. Sleep. 2010 Apr 1;33(4):427-436

709 Ropers HH. Genetics of early onset cognitive impairment. Annu Rev Genomics Hum Genet. 2010 Sep 22;11:161-87. Review.

708 Rosemann M, Ivashkevich A, Favor J, Dalke C, Hölter SM, Becker L, Racz I, Bolle I, Klempt M, Rathkolb B, Kalaydjiev S, Adler T, Aguilar A, Hans W, Horsch M, Rozman J, Calzada-Wack J, Kunder S, Gailus-Durner V, Fuchs H, Naton B, Schulz H, Beckers J, Busch DH, Burbach JPH, Smidt MP, Quintanilla-Martinez L, Esposito I, Klopstock T, Klingenspor M, Ollert M, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M, Atkinson M, Heinzmann U, Graw J. Microphthalmia, parkinsonism and enhanced nociception in Pitx3416insG mice. Mamm Genome 21:13-27. doi:10.1007/s00335-009-9235-0 ( Published online: 22 December 2009)

707 Roth CL, Enriori PJ, Gebhardt U, Hinney A, Müller HL, Hebebrand J, Reinehr T, Cowley MA. Changes of peripheral alpha-melanocyte-stimulating hormone inchildhood obesity. Metabolism. 2010 Feb;59(2):186-94. Epub 2009 Sep 18. PubMed PMID: 19766264.

706 Rubin D, Helwig U, Nothnagel M, Fölsch UR, Schreiber S, Schrezenmeir J. Association of postprandial and fasting triglycerides with traits of the metabolic syndrome in the Metabolic Intervention Cohort Kiel. Eur J Endocrinol. 2010 Apr;162(4):719-27. Epub 2010 Jan 14.

705 Rzehak P, Scherag A, Grallert H, Sausenthaler S, Koletzko S, Bauer CP, Schaaf B, von Berg A, Berdel D, Borte M, Herbarth O, Krämer U, Illig T, Wichmann HE, Hebebrand J, Heinrich J. GINI and LISA Study Group. Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years. Obes Facts. 2010 Jun;3(3):173-80

704 Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ. Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet. 2010 Aug 5;6(8). pii: e1001053.

703 Sauber J, Grothe J, Behm M, Scherag A, Grallert H, Illig T, Hinney A, Hebebrand J, Wiegand S, Grüters A, Krude H, Biebermann H. Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin. Eur J Endocrinol. 2010 Aug;163(2):259-64. Epub 2010 Jun 1.

702 Sauer S, Kliem M. Mass spectrometry tools for the classification and identification of bacteria. Nature Rev Microbiol. 2010 Jan;8(1):74-82.

701 Saxena R, Hivert MF, Langenberg C, Tanaka T, Pankow JS, Vollenweider P,Lyssenko V, Bouatia-Naji N, Dupuis J, Jackson AU, Kao WH, Li M, Glazer NL,Manning AK, Luan J, Stringham HM, Prokopenko I, Johnson T, Grarup N, BoesgaardTW, Lecoeur C, Shrader P, O'Connell J, Ingelsson E, Couper DJ, Rice K, Song K,Andreasen CH, Dina C, Köttgen A, Le Bacquer O, Pattou F, Taneera J,Steinthorsdottir V, Rybin D, Ardlie K, Sampson M, Qi L, van Hoek M, Weedon MN,Aulchenko YS, Voight BF, Grallert H, Balkau B, Bergman RN, Bielinski SJ,Bonnefond A, Bonnycastle LL, Borch-Johnsen K, Böttcher Y, Brunner E, Buchanan TA,Bumpstead SJ, Cavalcanti-Proença C, Charpentier G, Chen YD, Chines PS, CollinsFS, Cornelis M, J Crawford G, Delplanque J, Doney A, Egan JM, Erdos MR, FirmannM, Forouhi NG, Fox CS, Goodarzi MO, Graessler J, Hingorani A, Isomaa B, JørgensenT, Kivimaki M, Kovacs P, Krohn K, Kumari M, Lauritzen T, Lévy-Marchal C, Mayor V,McAteer JB, Meyre D, Mitchell BD, Mohlke KL, Morken MA, Narisu N, Palmer CN,Pakyz R, Pascoe L, Payne F, Pearson D, Rathmann W, Sandbaek A, Sayer AA, ScottLJ, Sharp SJ, Sijbrands E, Singleton A, Siscovick DS, Smith NL, Sparsø T, SwiftAJ, Syddall H, Thorleifsson G, Tönjes A, Tuomi T, Tuomilehto J, Valle TT, Waeber G, Walley A, Waterworth DM, Zeggini E, Zhao JH; GIANT consortium; MAGICinvestigators, Illig T, Wichmann HE, Wilson JF, van Duijn C, Hu FB, Morris AD,Frayling TM, Hattersley AT, Thorsteinsdottir U, Stefansson K, Nilsson P, Syvänen AC, Shuldiner AR, Walker M, Bornstein SR, Schwarz P, Williams GH, Nathan DM,Kuusisto J, Laakso M, Cooper C, Marmot M, Ferrucci L, Mooser V, Stumvoll M, Loos RJ, Altshuler D, Psaty BM, Rotter JI, Boerwinkle E, Hansen T, Pedersen O, Florez JC, McCarthy MI, Boehnke M, Barroso I, Sladek R, Froguel P, Meigs JB, Groop L,Wareham NJ, Watanabe RM. Genetic variation in GIPR influences the glucose andinsulin responses to an oral glucose challenge. Nat Genet. 2010 Feb;42(2):142-8.


700    Sayk F, Heutling D, Dodt C, Iwen KA, Wellhoner JP, Scherag S, Hinney A,Hebebrand J, Lehnert H. Sympathetic Function in Human Carriers of Melanocortin-4 Receptor Gene Mutations. J Clin Endocrinol Metab. 2010 Feb 10. [Epub ahead of print] PubMed PMID: 20147580.

699    Schaefer AS, Richter GM, Nothnagel M, Laine ML, Noack B, Glas J, Schrezenmeir J, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S. COX-2 is associated with periodontitis in Europeans. J Dent Res. 2010 Apr;89(4):384-8. Epub 2010 Feb 22.

698    Schaefer AS, Richter GM, Nothnagel M, Manke T, Dommisch H, Jacobs G, Arlt A, Rosenstiel P, Noack B, Groessner-Schreiber B, Jepsen S, Loos BG, Schreiber S. A genome-wide association study identifies GLT6D1 as a susceptibility locus for periodontitis. Hum Mol Genet. 2010 Feb 1;19(3):553-62. Epub 2009 Nov 6.

697    Schardt DM, Erk S, Nüsser C, Nöthen MM, Cichon S, Rietschel M, Treutlein J, Goschke T, Walter H. Volition diminishes genetically mediated amygdala hyperreactivity. Neuroimage. 2010 Nov 15;53(3):943-51. Epub 2009 Dec 5. pmid 19969089.

696    Schebelle L, Wolf C, Stribl C, Javaheri T, Schnütgen F, Ettinger A, Ivics Z, Hansen J, Ruiz P, von Melchner H, Wurst W, Floss T. Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps. Nucleic Acids Res. 2010 May 38 (9): e106.

695    Schepers E, Glorieux G, Dou L, Cerini C, Gayrard N, Louvet L, Maugard C, Preus P, Rodriguez-Ortiz M, Argiles A, Brunet P, Cohen G, Jankowski J, Jankowski V, Massy Z, Rodriguez M, Vanholder R. Guanidino compounds as cause of cardiovascular damage in chronic kidney disease: an in vitro evaluation.; Blood Purif. 2010;30(4):277-87.

694    Schepers E, Glorieux G, Jankowski V, Dhondt A, Jankowski J, Vanholder R. Dinucleoside polyphosphates: newly detected uraemic compounds with an impact on leucocyte oxidative burst. Nephrol Dial Transplant. 2010 Aug;25(8):2636-44. Epub 2010 Feb 26.

693    Scherag A, Hebebrand J, Wichmann HE, Jöckel KH. Evaluating Strategies for Marker Ranking in Genome-wide Association Studies of Complex Traits. Methods Inf Med. 2010 Dec 8;49(6):632-40.

692    Scherag A, Jarick I, Grothe J, Biebermann H, Scherag S, Volckmar AL, Vogel CIG, Greene B, Hebebrand J, Hinney A. "Investigation of a Genome Wide Association Signal for Obesity: Synthetic Association and Haplotype Analyses at the Melanocortin 4 Receptor gene Locus." PLoS ONE 2010; 5(11):e13967

691    Scherag S, Hebebrand J, Hinney A. Eating disorders: the current status ofmolecular genetic research. Eur Child Adolesc Psychiatry. 2010 Mar;19(3):211-26. Epub 2009 Dec 24. PubMed PMID: 20033240; PubMed Central PMCID: PMC2839487.

690    Schlicker A, Albrecht M. FunSimMat update: new features for exploringfunctional similarity. Nucleic Acids Res. 2010 Jan;38(Database issue):D244-8.

689    Schlicker F, Lengauer T, Albrecht M. Improving disease gene prioritization using the semantic similarity of Gene Ontology terms. Bioinformatics. 2010 Sep 15;26(18):i561-7

688    Schmidt M, Petry IB, Böhm D, Lebrecht A, von Törne C, Gebhard S, Gerhold-Ay a, Cotarelo C, Battista M, Schormann W, Freis E, Selinski S, Ickstadt K, Rahnenführer J, Sebastian M, Schuler M, Koelbl H, Gehrmann M, Hengstler JG. Ep-Cam RNA expression predicts metastasis-free survival in three cohorts of untreated node-negative breast cancer. Breast Cancer Res Treat. 2010 Mar 30. [Epub ahead of print]. doi:10.1007/s10549-010-0856-5

687    Schmidt MV, Trümbach D, Weber P, Wagner K, Scharf SH, Liebl C, Datson N, Namendorf C, Gerlach T, Kühne C, Uhr M, Deussing JM, Wurst W, Binder EB, Holsboer F, Müller MB. Individual stress vulnerability is predicted by short-term memory and AMPA receptor subunit ratio in the hippocampus. J Neurosci. 2010 Dec 15;30(50):16949-58.

686    Schmidt S, Schneider L, Essmann F, Cirstea IC, Kuck F, Kletke A, Jänicke RU, Wiek C, Hanenberg H, Ahmadian MR, Schulze-Osthoff K, Nürnberg B, Piekorz RP. The centrosomal protein TACC3 controls paclitaxel sensitivity by modulating a premature senescence program. Oncogene 29, 6184-92. PMID: 20729911

685    Schmitt AO, Aßmus J, Bortfeldt RH, Brockmann GA. CandiSNPer: a web-tool for the identification of candidate SNPs for causal variants. Bioinformatics. 2010;26(7):969-970

684    Schnabel RB, Baumert J, Barbalic M, Dupuis J, Ellinor PT, Durda P, Dehghan A, Bis JC, Illig T, Morrison AC, Jenny NS, Keaney JF Jr, Gieger C, Tilley C, Yamamoto JF, Khuseyinova N, Heiss G, Doyle M, Blankenberg S, Herder C, Walston JD, Zhu Y, Vasan RS, Klopp N, Boerwinkle E, Larson MG, Psaty BM, Peters A, Ballantyne CM, Witteman JC, Hoogeveen RC, Benjamin EJ, Koenig W, Tracy RP. Duffy antigen receptor for chemokines polymorphism regulates circulating concentrations of MCP-1. Blood 2010;115:5289-99.

683    Schoensiegel F, Ivandic B, Geis NA, Schrewe A, Katus HA, Bekeredjian R. High Throughput Echocardiography in Conscious Mice: Training and Primary Screens. Ultraschall Med. 2010 Feb 24. [Epub ahead of print]

682    Scholz AK, Klebl BM, Morkel M, Lehrach H, Dahl A, Lange BMH. A flexible multi-well format for immunofluorescence screening microscopy of small molecule inhibitors. Assay Drug Dev Technol. 2010 Sep 13. [Epub ahead of print].

681    Scholze A, Katharina Krueger, Madeleine Diedrich, Christine Rath, Anja Torges, Vera Jankowski, Alexandra Maier, Florian Thilo, Walter Zidek,  Martin Tepel: Superoxide dismutase type 1 in monocytes of chronic kidney disease patients. Amino Acids. 2010 Oct 8. [Epub ahead of print]

680    Schramm, G., Kannabiran, N. & König, R. Regulation patterns in signaling networks of cancer, BMC Systems Biology, 4, 162.

679    Schramm, G., Surmann, E.M., Wiesberg, S., Oswald, M., Reinelt, G., Eils, R. & König, R. Analyzing the regulation of metabolic pathways in human breast cancer, BMC Medical Genomics, 3:39.

678    Schramm, G., Wiesberg, S., Diessl, N., Kranz, A.L., Sagulenko, V., Oswald, M., Reinelt, G., Westermann, F., Eils, R. & König, R. PathWave: Discovering patterns of differentially regulated enzymes in metabolic pathways, Bioinformatics, 2010 Mar 24. [Epub ahead of print]

677    Schröder, C., Jacob, A., Tonack, S., Radon, T., Sill, M., Zucknick, M., Rüffer, S., Costello, E., Neoptolemos, J., Crnogorac-Jurcevic, T., Bauer, A., Fellenberg, K. & Hoheisel, J.D. Dual-color proteomic profiling of complex samples with a microarray of 810 cancer-specific antibodies. Mol. Cell. Prot. 9, 1271-1280.

676    Schubert W. On the origin of cell functions encoded in the toponome. Journal of Biotechnology, Volume 149, Issue 4, 15 September 2010, Pages 252-259, doi:10.1016/j.jbiotec.2010.03.0099

675    Schulte JH, Marschall T, Martin M, Rosenstiel P, Mestdagh P, Schlierf S, Thor T, Vandesompele J, Eggert A, Schreiber S, Rahmann S, Schramm A. Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorableneuroblastoma. Nucleic Acids Res. 2010 Sep 1;38(17):5919-28. Epub 2010 May 13.PubMed PMID: 20466808; PubMed Central PMCID: PMC2943620.

674    Schulte, J, Schowe, B, Mestdagh, P, Kaderali, L, Kalaghatgi, P, Schlierf, S, Vermeulen, J, Brockmeyer, B, Pajtler, K, Thor, T, de Preter, K, Speleman, F, Morik, K, Eggert, A, Vandesompele, J, Schramm, A. Accurate Prediction of Neuroblastoma Outcome based on miRNA Expression Profiles.  International Journal of Cancer, 27:2374-85

673    Schulte, JH, Marschall T, Martin M, Rosenstiel P, Mestdagh P, Schlierf S, Thor T, Vandesompele J, Eggert A, Schreiber S, Rahmann S, and Schramm A. Deep sequencing reveals differential expression of microRNAs in favourable versus unfavourable neuroblastoma.  Nucleic Acids Research, 38:5919-28

672    Schulze TG, Alda M, Adli M, Akula N, Ardau R, Bui ET, Chillotti C, Cichon S, Czerski P, Del Zompo M, Detera-Wadleigh SD, Grof P, Gruber O, Hashimoto R, Hauser J, Hoban R, Iwata N, Kassem L, Kato T, Kittel-Schneider S, Kliwicki S, Kelsoe JR, Kusumi I, Laje G, Leckband SG, Manchia M, Macqueen G, Masui T, Ozaki N, Perlis RH, Pfennig A, Piccardi P, Richardson S, Rouleau G, Reif A, Rybakowski JK, Sasse J, Schumacher J, Severino G, Smoller JW, Squassina A, Turecki G, Young LT, Yoshikawa T, Bauer M, McMahon FJ. The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment. Neuropsychobiology 62:72-78. DOI: 10.1159/000314708

671    Schumann G, Loth E, Banaschewski T, Barker G, Buechel C, Conrod PJ, Dalley, JW, Flor H, Gallinat J, Garavan H, Heinz A, Itterman B, Lathrop M, Martinot JL, Mann K, Poline JB, Robbins TW, Rietschel M, Reed L, Smolka M, Spanagel R, Stephens DN, Stroehle A, Paus T, and the IMAGEN consortium. The IMAGEN study: Reinforcement-related behaviour in normal brain function and psychopathology. Mol Psychiatry, 15:1128-39 (15.049)

670    Schwarz DF, König IR, Ziegler A. On safari to Random Jungle: a fast implementation of Random Forests for high dimensional data. Bioinformatics 2010 26: 1752-8

669    Seeger TS, Frank D, Rohr C, Will R, Just S, Grund C, Lyon R, Luedde M, Koegl M, Sheikh F, Rottbauer W, Franke WW, Katus HA, Olson EN, Frey N. Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo. Circ Res. 106(5):880-90

668    Seidel K, Schöls L, Nuber S, Petrasch-Parwez E, Gierga K, Wszolek Z, Dickson D, Gai WP, Bornemann A, Riess O, Rami A, den Dunnen WFA, Deller T, Rüb U, Krüger R. First appraisal of brain pathology owing to A30P mutant alpha-synuclein. Ann Neurol (published online 20.01.2010); DOI: 10.1002/ana.21966

667    Seidel S, Garvalov BK, Wirta V, von Stechow L, Schänzer A, Meletis K, Wolter M, Sommerlad D, Henze AT, Nistér M, Reifenberger G, Lundeberg J, Frisén J, Acker T. A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha.  Brain. 2010 Apr;133(Pt 4):983-95.

666    Shan J, Kushnir A, Betzenhauser MJ, Reiken S, Li J, Lehnart SE, Lindegger N, Mongillo M, Mohler PJ, Marks AR. Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice.  J Clin Invest  2010; 120, 4388-98

665    Sharma CM, Hoffmann S, Darfeuille F, Reignier J, Findeiß S, Sittka A, Chabas S, Reiche K, Hackermüller J, Reinhardt R, Stadler PF, Vogel J. The primary transcriptome of the major human pathogen Helicobacter pylori. Nature. 2010 Mar 11; 464(7286):250-5. PMID: 20164839.

664    Shi L, Campbell G, Jones WD, Campagne F, Wen Z, Walker SJ, Su Z, Chu TM, Goodsaid FM, Pusztai L, Shaughnessy JD Jr, Oberthuer A, Thomas RS, Paules RS, Fielden M, Barlogie B, Chen W, Du P, Fischer M, Furlanello C et al. The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models.. Nat Biotechnol, 2010, 28(8):827-838.

663    Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schulz C, Rozman J, Höller D, Qiu CH, Londono MB, Jedlicka P, Schwarzacher SW, Wolfer DP, Ehrhardt N, Heuchel R, Nezis I, Brech A, Schmidt MHH, Fuchs H, Gailus-Durner V, Klingenspor M, Bogler O, Wurst W, Deller T, Hrab? de Angelis M, Dikic I. CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice. EMBO J 29(14):2421-32 doi:10.1038/emboj.2010.120

662    Sill, M., Schröder, C., Hoheisel, J.D., Benner, A. & Zucknick, M. Assessment and optimisation of normalisation methods for dual-colour antibody microarrays. BMC Bioinformatics 11, 556.

661    Simard, J.R., M. Getlik, C. Grütter, R. Schneider, S. Wulfert, D. Rauh. Fluorophore-labeling of the glycine-rich loop as a method of identifying inhibitors which bind to active and inactive kinase conformations. J Am Chem Soc, 2010, 132(12):4152-60

660    Sina C, Arlt A, Gavrilova O, Midtling E, Kruse ML, Müerköster SS, Kumar R, Fölsch UR, Schreiber S, Rosenstiel P, Schäfer H. Ablation of gly96/immediate early gene-X1 (gly96/iex-1) aggravates DSS-induced colitis in mice: role for gly96/iex-1 in the regulation of NF-kappaB. Inflamm
Bowel Dis. 2010 Feb;16(2):320-31.

659    Sinha R, Lenser T, Jahn N, Gausmann U, Friedel S, Szafranski K, Huse K, Rosenstiel P, Hampe J, Schuster S, Hiller M, Backofen R, Platzer M. TassDB2 - A comprehensive database of subtle alternative splicing events. BMC Bioinformatics. 2010 Apr 29;11:216.

658    Sinha R, Thorsten Lenser, Niels Jahn, Ulrike Gausmann, Swetlana Friedel, Karol Szafranski, Klaus Huse, Philip Rosenstiel, Jochen Hampe, Stefan Schuster, Michael Hiller, Rolf Backofen and Matthias Platzer. TassDB2 - A comprehensive database of subtle alternative splicing events  BMC Bioinformatics 2010, 11:216doi:10.1186/1471-2105-11-216

657    Slabicki M, Theis M, Krastev DB, Samsonov S, Mundwiller E, Junqueira M, Paszkowski-Rogacz M, Teyra J, Heninger AK, Poser I, Prieur F, Truchetto J, Confavreux C, Marelli C, Durr A, Camdessanche JP, Brice A, Shevchenko A, Pisabarro MT, Stevanin G, Buchholz F. A genome-scale DNA repair RNAi screen identifies SPG48 as a novel gene associated with hereditary spastic paraplegia. PLoS Biol. 2010 Jun 29;8(6)

656    Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, Vitart V, Campbell H, Mälarstig A, Wiggins KL, Van Duijn CM, McArdle WL, Pankow JS, Johnson AD, Silveira A, McKnight B, Uitterlinden AG, Aleksic N, Meigs JB, Peters A, Koenig W et al.  Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor. Circulation 2010;121:1382-1392.

655    Soehn AS, Franck T, Biskup S, Giaime E, Melle C, Rott R, Cebo D, Kalbacher H, Ott E, Pahnke J, Meitinger T, Krüger R, Gasser T, Berg D, von Eggeling F, Engelender S, Alves da Costa C, Riess O. Periphilin is a novel interactor of synphilin-1, a protein implicated in Parkinson's disease. Neurogenetics 11:203-215

654    Soler-Lopez M, Zanzoni A, Lluis R, Stelzl U, Aloy P. Interactome mapping suggests new mechanistic details underlying Alzheimer's disease. Genome Res. 2011 Mar;21(3):364-76.

653    Song Z, von Figura G, Liu Y, Kraus JM, Torrice C, Dillon P, Rudolph-Watabe M, Ju Z, Kestler HA, Sanoff H, Rudolph KL. Lifestyle impacts on the aging-associated expression of biomarkers of DNA damage and telomere dysfunction in human blood. Aging Cell. 2010; in press.

652    Soranzo N, Sanna S, Wheeler E, Gieger C, Radke D, Dupuis J, Bouatia-Naji N,Langenberg C, Prokopenko I, Stolerman E, Sandhu MS, Heeney MM, Devaney JM, ReillyMP, Ricketts SL, Stewart AF, Voight BF, Willenborg C, Wright B, Altshuler D,Arking D, Balkau B, Barnes D, Boerwinkle E, Böhm B, Bonnefond A, Bonnycastle LL, Boomsma DI, Bornstein SR, Böttcher Y, Bumpstead S, Burnett-Miller MS, Campbell H,Cao A, Chambers J, Clark R, Collins FS, Coresh J, de Geus EJ, Dei M, Deloukas P, Döring A, Egan JM, Elosua R, Ferrucci L, Forouhi N, Fox CS, Franklin C, Franzosi MG, Gallina S, Goel A, Graessler J, Grallert H, Greinacher A, Hadley D, Hall A,Hamsten A; on behalf of Procardis Consortium, Hayward C, Heath S, Herder C,Homuth G, Hottenga JJ, Hunter-Merrill R, Illig T, Jackson AU, Jula A, Kleber M,Knouff CW, Kong A, Kooner J, Köttgen A, Kovacs P, Krohn K, Kühnel B, Kuusisto J, Laakso M, Lathrop M, Lecoeur C, Li M, Li M, Loos RJ, Luan J, Lyssenko V, Mägi R, Magnusson PK, Mälarstig A, Mangino M, Martínez-Larrad MT, März W, McArdle WL,McPherson R, Meisinger C, Meitinger T, Melander O, Mohlke KL, Mooser VE, MorkenMA, Narisu N, Nathan DM, Nauck M, O'Donnell C, Oexle K, Olla N, Pankow JS, Payne F, Peden JF, Pedersen NL, Peltonen L, Perola M, Polasek O, Porcu E, Rader DJ,Rathmann W, Ripatti S, Rocheleau G, Roden M, Rudan I, Salomaa V, Saxena R,Schlessinger D, Schunkert H, Schwarz P, Seedorf U, Selvin E, Serrano-Ríos M,Shrader P, Silveira A, Siscovick D, Song K, Spector TD, Stefansson K,Steinthorsdottir V, Strachan DP, Strawbridge R, Stumvoll M, Surakka I, Swift AJ, Tanaka T, Teumer A, Thorleifsson G, Thorsteinsdottir U, Tönjes A, Usala G, VitartV, Völzke H, Wallaschofski H, Waterworth DM, Watkins H, Wichmann HE, Wild SH,Willemsen G, Williams GH, Wilson JF, Winkelmann J, Wright AF; WTCCC, Zabena C,Zhao JH, Epstein SE, Erdmann J, Hakonarson HH, Kathiresan S, Khaw KT, Roberts R, Samani NJ, Fleming MD, Sladek R, Abecasis G, Boehnke M, Froguel P, Groop L,McCarthy MI, Kao WH, Florez JC, Uda M, Wareham NJ, Barroso I, Meigs JB. Common variants at ten genomic loci influence hemoglobin A1C levels via glycemic andnon-glycemic pathways. Diabetes. 2010 Sep 21.

651    Sos ML, Rode HB, Heynck S, Peifer M, Fischer F, Klüter S, Pawar VG, Reuter C, Heuckmann JM, Weiss J, Ruddigkeit L, Rabiller M, Koker M, Simard JR, Getlik M, Yuza Y, Chen TH, Greulich H, Thomas RK, Rauh D. Chemogenomic profiling provides insights into the limited activity of irreversible EGFR Inhibitors in tumor cells expressing the T790M EGFR resistance mutation. Cancer Res. 2010 Feb 1;70(3):868-74.

650    Sotoodehnia N, Isaacs A, de Bakker PI, Dörr M, Newton-Cheh C, Nolte IM, van der Harst P, Müller M, Eijgelsheim M, Alonso A, Hicks AA, Padmanabhan S, Hayward C, Smith AV, Polasek O, Giovannone S, Fu J, Magnani JW, Marciante KD, Pfeufer A, .., Kääb S, Arking DE. Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet. 2010 Dec;42(12):1068-76. Epub 2010 Nov 14.

649    Spanagel R, Bartsch D, Brors B, Dahmen N, Deussing J, Eils R, Ende G, Gallinat J, Gebicke-Haerter P, Heinz A, Kiefer F, Jager W, Mann K, Matthaus F, Nothen M, Rietschel M, Sartorius A, Schutz G, Sommer WH, Sprengel R, Walter H, Wichmann E, Wienker T, Wurst W, Zimmer A. An integrated genome research network for studying the genetics of alcohol addiction. Addict Biol 15:369-379.

648    Spanagel R. Are metabotropic glutamate receptors promising targets for the treatment of alcoholism? Biol Psychiatry, 67:798-9 (8.926)

647    Speliotes EK, Willer CJ, Berndt SI, Monda KL, Thorleifsson G, Jackson AU, Allen HL, Lindgren CM, Luan Ja, Mägi R, Randall JC, Vedantam S, Winkler TW, Qi L, Workalemahu T, Heid IM, Steinthorsdottir V, Weedon MN, Wheeler E, Wood AR, Ferreira T, Weyant RJ, Segrè AV, Estrada K, Liang L, Nemesh J, Park J-H, Gustafsson S, Kilpeläinen TO, Yang J, Bouatia-Naji N, Esko T, Feitosa MF, Kutalik Z, Mangino M, Raychaudhuri S, Scherag A, Smith AV, Welch R, Zhao JH, Aben KK, Absher DM, Amin N, Dixon AL, Fisher E, Glazer NL, Goddard ME, Heard-Costa NL, Hoesel V, Hottenga J-J, Johansson Å, Johnson T, Ketkar S, Lamina C, Li S, Moffatt MF, Myers RH, Narisu N, Perry JRB, Peters MJ, Preuss M, Ripatti S, Rivadeneira F, Sandholt C, Scott LJ, Timpson NJ, Tyrer JP, Wingerden Sv, Watanabe RM, White CC, Wiklund F, Barlassina C, Chasman DI, Cooper MN, Jansson J-O, Lawrence RW, Pellikka N, Prokopenko I, Shi J, Thiering E, Alavere H, Alibrandi MTS, Almgren P, Arnold AM, Aspelund T, Atwood LD, Balkau B, Balmforth AJ, Bennett AJ, Ben-Shlomo Y, Bergman RN, Bergmann S, Biebermann H, Blakemore AIF, Boes T, Bonnycastle LL, Bornstein SR, Brown MJ, Buchanan TA, Busonero F, Campbell H, Cappuccio FP, Cavalcanti-Proença C, Chen Y-DI, Chen C-M, Chines PS, Clarke R, Coin L, Connell J, Day INM, Heijer Md, Duan J, Ebrahim S, Elliott P, Elosua R, Eiriksdottir G, Erdos MR, Eriksson JG, Facheris MF, Felix SB, Fischer-Posovszky P, Folsom AR, Friedrich N, Freimer NB, Fu M, Gaget S, Gejman PV, Geus EJC, Gieger C, Gjesing AP, Goel A, Goyette P, Grallert H, Gräßler J, Greenawalt DM, Groves CJ, Gudnason V, Guiducci C, Hartikainen A-L, Hassanali N, Hall AS, Havulinna AS, Hayward C, Heath AC, Hengstenberg C, Hicks AA, Hinney A, Hofman A, Homuth G, Hui J, Igl W, Iribarren C, Isomaa B, Jacobs KB, Jarick I, Jewell E, John U, Jørgensen T, Jousilahti P, Jula A, Kaakinen M, Kajantie E, Kaplan LM, Kathiresan S, Kettunen J, Kinnunen L, Knowles JW, Kolcic I, König IR, Koskinen S, Kovacs P, Kuusisto J, Kraft P, Kvaløy K, Laitinen J, Lantieri O, Lanzani C, Launer LJ, Lecoeur C, Lehtimäki T, Lettre G, Liu J, Lokki M-L, Lorentzon M, Luben RN, Ludwig B, MAGIC, Manunta P, Marek D, Marre M, McArdle WL, McCarthy A, McKnight B, Meitinger T, Melander O, Meyre D, Midthjell K, Montgomery GW, Morken MA, Morris AP, Mulic R, Ngwa JS, Nelis M, Neville MJ, Nyholt DR, O'Donnell CJ, O?Rahilly S, Ong KK, Oostra B, Paré G, Parker AN, Perola M, Pichler I, Pietiläinen KH, Platou CGP, Polasek O, Pouta A, Rafelt S, Raitakari O, Rayner NW, Ridderstråle M, Rief W, Ruokonen A, Robertson NR, Rzehak P, Salomaa V, Sanders AR, Sandhu MS, Sanna S, Saramies J, Savolainen MJ, Scherag S, Schipf S, Schreiber S, Schunkert H, Silander K, Sinisalo J, Siscovick DS, Smit JH, Soranzo N, Sovio U, Stephens J, Stringham HM, Surakka I, Swift AJ, Tammesoo M-L, Tardif J-C, Teder-Laving M, Teslovich TM, Thompson JR, Thomson B, Tönjes A, Tuomi T, Meurs JBJv, Ommen G-Jv, Vatin V, Viikari J, Visvikis-Siest S, Vitart V, Vogel CIG, Voight BF, Waite LL, Wallaschofski H, Walters GB, Widen E, Wiegand S, Wild SH, Willemsen G, Witte DR, Witteman JC, Xu J, Zhang Q, Zgaga L, Ziegler A, Zitting P, Beilby JP, Farooqi IS, Hebebrand J, Huikuri HV, James AL, Kähönen M, Levinson DF, Macciardi F, Nieminen MS, Ohlsson C, Palmer LJ, Ridker PM, Stumvoll M, Beckmann JS, Boeing H, Boerwinkle E, Boomsma DI, Caulfield MJ, Chanock SJ, Collins FS, Cupples LA, Smith GD, Erdmann J, Froguel P, Grönberg H, Gyllensten U, Hall P, Hansen T, Harris TB, Hattersley AT, Hayes RB, Heinrich J, Hu FB, Hveem K, Illig T, Jarvelin M-R, Kaprio J, Karpe F, Khaw K-T, Kiemeney LA, Krude H, Laakso M, Lawlor DA, Metspalu A, Munroe PB, Ouwehand WH, Pedersen O, Penninx BW, Peters A, Pramstaller PP, Quertermous T, Reinehr T, Rissanen A, Rudan I, Samani NJ, Schwarz PEH, Shuldiner AR, Spector TD, Tuomilehto J, Uda M, Uitterlinden A, Valle TT, Wabitsch M, Waeber G, Wareham NJ, Watkins H, Wilson JF, Wright AF, Zillikens MC, Chatterjee N, McCarroll SA, Purcell S, Schadt EE, Visscher PM, Assimes TL, Borecki IB, Deloukas P, Fox CS, Groop LC, Haritunians T, Hunter DJ, Kaplan RC, Mohlke KL, O'Connell JR, Peltonen L, Schlessinger D, Strachan DP, Duijn CMv, Wichmann H-E, Frayling TM, Thorsteinsdottir U, Abecasis GR, Barroso I, Boehnke M, Stefansson K, North KE, McCarthy MI, Hirschhorn JN, Ingelsson E, Loos RJF. Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index. Nat Genet 42: 937-48

646    Stamelou M, de Silva R, Arias-Carrion O, Boura E, Höllerhage M, Oertel WH, Müller U, Höglinger GU. Rational therapeutic approaches to progressive supranuclear palsy. Brain. 2010;133:1578-90.

645    Stange DE, Engel F, Longerich T, Koo BK, Koch M, Delhomme N, Aigner M, Toedt G, Schirmacher P, Lichter P, Weitz J, Radlwimmer B. Expression of an ASCL2 related stem cell signature and IGF2 in colorectal cancer liver metastases with 11p15.5 gain. Gut. 2010 Sep;59(9):1236-44. Epub 2010 May 17.

644    Stark K, Esslinger UB, Reinhard W, Petrov G, Winkler T, Komajda M, Isnard R, Charron P, Villard E, Cambien F, Tiret L, Aumont MC, Dubourg O, Trochu JN, Fauchier L, Degroote P, Richter A, Maisch B, Wichter T, Zollbrecht C, Grassl M, Schunkert H, Linsel-Nitschke P, Erdmann J, Baumert J, Illig T, Klopp N, Wichmann HE, Meisinger C, Koenig W, Lichtner P, Meitinger T, Schillert A, König IR, Hetzer R, Heid IM, Regitz-Zagrosek V, Hengstenberg C. Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy. PLoS Genet 2010;6:e1001167

643    Steer, B. Adler, S. Jonjic, J. P. Stewart, and H. Adler. A gammaherpesvirus complement regulatory protein promotes initiation of infection by activation of protein kinase Akt/PKB (PLoS ONE, 5 (7) (2010): e11672).

642    Steffens M, Becker T, Sander T, Fimmers R, Herold C, Holler DA, Leu C, Herms S, Cichon S, Bohn B, Gerstner T, Griebel M, Markus M. Nöthen MM, Wienker TF, Baur MP. Feasible and successful: Genome-wide Interaction Analysis (GWIA) involving all 1.9 x 10E11 pair-wise interaction tests. Hum Hered. 2010 Mar 31;69(4):268-284.

641    Steinberg S, Mors O, Børglum AD, Gustafsson O, Werge T, Mortensen PB, Andreassen OA, Sigurdsson E, Thorgeirsson TE, Böttcher Y, Olason P, Ophoff RA, Cichon S, Gudjonsdottir IH, Pietiläinen OP, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Athanasiu L, Suvisaari J, Lonnqvist J, Paunio T, Hartmann A, Jürgens G, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Breuer R, Möller HJ, Giegling I, Glenthøj B, Rasmussen HB, Mattheisen M, Bitter I, Réthelyi JM, Sigmundsson T, Fossdal R, Thorsteinsdottir U, Ruggeri M, Tosato S, Strengman E; GROUP, Kiemeney LA, Melle I, Djurovic S, Abramova L, Kaleda V, Walshe M, Bramon E, Vassos E, Li T, Fraser G, Walker N, Toulopoulou T, Yoon J, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Jönsson EG, Terenius L, Agartz I, Petursson H, Nöthen MM, Rietschel M, Peltonen L, Rujescu D, Collier DA, Stefansson H, St Clair D, Stefansson K. Expanding the range of ZNF804A variants conferring risk of psychosis. Mol Psychiatry. 2010 Jan 5. Stefansson K. Expanding the range of ZNF804A variants conferring risk of psychosis. Mol Psychiatry. 2011 Jan;16(1):59-66. doi:10.1038/mp.2009.149

640    Strohmaier J, Frank J, Wendland JR, Schumacher J, Jamra RA, Treutlein J, Nieratschker V, Breuer R, Mattheisen M, Herms S, Mühleisen TW, Maier W, Nöthen MM, Cichon S, Rietschel M, Schulze TG. A reappraisal of the association between Dysbindin (DTNBP1) and schizophrenia in a large combined case-control and family-based sample of German ancestry. Schizophr Res. 2010 May;118(1-3):98-105. Epub 2010 Jan 18.

639    Stuart PE, Nair RP, Ellinghaus E, Ding J, Tejasvi T, Gudjonsson JE, Li Y, Weidinger S, Eberlein B, Gieger C, Wichmann HE, Kunz M, Ike R, Krueger GG, Bowcock AM, Mrowietz U, Lim HW, Voorhees JJ, Abecasis GR, Weichenthal M, Franke A, Rahman P, Gladman DD, Elder JT. Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat Genet. 2010 Nov;42(11):1000-4

638    Subramanian D, Laketa V, Muller R, Tischer C, Zarbakhsh S, Pepperkok R, Schultz C. Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells. Nat Chem Biol 6: 324-326.

637    Suliman H, Schumacher J, Becker T, Cichon S, Schulze TG, Propping P, Rietschel M, Nöthen MM, Jamra RA. Association study of 20 genetic variants at the (D)-amino acid oxidase gene in schizophrenia. Psychiatr Genet. 2010 Apr;20(2):82-3.

636    Sun LD, Cheng H, Wang ZX, Zhang AP, Wang PG, Xu JH, Zhu QX, Zhou HS, Ellinghaus E, Zhang FR, Pu XM, Yang XQ, Zhang JZ, Xu AE, Wu RN, Xu LM, Peng L, Helms CA, Ren YQ, Zhang C, Zhang SM, Nair RP, Wang HY, Lin GS, Stuart PE, Fan X, Chen G, Tejasvi T, Li P, Zhu J, Li ZM, Ge HM, Weichenthal M, Ye WZ, Zhang C, Shen SK, Yang BQ, Sun YY, Li SS, Lin Y, Jiang JH, Li CT, Chen RX, Cheng J, Jiang X, Zhang P, Song WM, Tang J, Zhang HQ, Sun L, Cui J, Zhang LJ, Tang B, Huang F, Qin Q, Pei XP, Zhou AM, Shao LM, Liu JL, Zhang FY, Du WD, Franke A, Bowcock AM, Elder JT, Liu JJ, Yang S, Zhang XJ.  Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet 2010;42(11):1005-9.

635    Suratanee, A., Rebhan, I., Matula, P., Kaderali, L., Rohr, K., Bartenschlager, R., Eils, R. & König, R. Detecting host factors involved in virus infection by observing the clustering of infected cells in siRNA screening images, Bioinformatics, 26 ECCB 2010, i1-i6

634    Sury MD; Chen JX; Selbach M. The SILAC fly allows for accurate protein quantification in vivo Molecular & Cellular Proteomics 9 (10): 2173-2183 (2010-10)

633    Suttner K, Depner M, Wetzke M, Klopp N, von Mutius E, Illig T, Sparwasser T, Kabesch M. Genetic variants harbored in the forkhead box protein 3 locus increase hay fever risk. J Allergy Clin Immunol. 2010 Jun;125(6):1395-9. Epub 2010 Apr 15

632    Sventoraityte J, Zvirbliene A, Franke A, Kwiatkowski R, Kiudelis G, Kupcinskas L, Schreiber S. NOD2, IL23R and ATG16L1 polymorphisms in Lithuanian patients with inflammatory bowel disease.  World J Gastroenterol. 2010 Jan 21;16(3):359-64.

631    Sylvester M, Kliche S, Lange S, Geithner S, Klemm C, Schlosser A, Grossmann A, Stelzl U, Schraven B, Krause E, Freund C. Adhesion and degranulation promoting adapter protein (ADAP) is a central hub for phosphotyrosine-mediated interactions in T cells. PLoS One. 2010 Jul 22;5(7):e11708.

630    Szczyrba, J., Loprich, E., Wach, S., Jung, V., Unteregger, G., Barth, S., Grobholz, R., Wieland, W., Stohr, R., Hartmann, A., Wullich, B., and Grässer, F. The MicroRNA Profile of Prostate Carcinoma Obtained by Deep Sequencing. Mol Cancer Res 8(4), 529-38.

629    Tan, S., Scherag, A., Janssen, O.E., Hahn, S., Lahner, H., Dietz, T., Scherag, S., Grallert, H., Ganz Vogel, C.I., Kimmig, R., Illig, T., Mann, K., Hebebrand, J., Hinney, A."Large effects on body mass index and insulin resistance of fat mass and obesity associated gene (FTO) variants in patients with polycystic ovary syndrome (PCOS)." BMC Med Genet 11:12, 1-9 (2010)

628    Taudien S, Groth M, Huse K, Petzold A, Szafranski K, Hampe J, Rosenstiel P, Schreiber S, Platzer M. Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing. BMC Genomics. 2010 Apr 19;11(1):252

627    Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ, Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J, Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Cho YS, Go MJ, Kim YJ, Lee J-Y, Park T, Kim KJ, Sim X, Ong RT-H, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Zhao JH, Yuan X, Luan Ja, Lamina C, CARDIoGRAM Consortium, ENGAGE Consortium, Candidate Gene Association Resource (CARe) Lipids Working Group, Ziegler A, Zhang W, Zee RYL, Wright AF, Witteman JCM, Wilson JF, Willemsen G, Wichmann H-E, Whitfiel JB, Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF, Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH, Sinisalo J, Silander K, Sijbrands EJG, Scuteri A, Scott J, Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C, Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM, Pramstaller PP, Pichler I, Perola M, Penninx BWJH, Pedersen NL, Pattaro C, Parker AN, Pare G, Oostra BA, O?Donnell CJ, Nieminen MS, Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI, McArdle W, Masson D, Martin NG, Marroni F, Mangino M, Magnusson P, Lucas G, Luben R, Loos RJF, Lokki M, Lettre G, Langenberg C, Launer LJ, Lakatta EG, Laaksonen R, Kyvik KO, Kronenberg F, König IR, Khaw K-T, Kaprio J, Kaplan LM, Johansson Å, Jarvelin M-R, Janssens ACJW, Ingelsson E, Igl W, Hovingh GK, Hottenga J-J, Hofman A, Hicks AA, Hengstenberg C, Heid IM, Hayward C, Havulinna AS, Hastie ND, Harris TB, Haritunians T, Hall AS, Gyllensten U, Guiducci C, Groop LC, Gonzalez E, Gieger C, Freimer NB, Ferrucci L, Erdmann J, Elliott P, Ejebe KG, Döring A, Dominiczak AF, Demissie S, Deloukas P, Geus EJCd, Faire Ud, Crawford G, Collins FS, Chen Y-dI, Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI, Boekholdt SM, Bergman RN, Barroso I, Bandinelli S, Ballantyne CM, Assimes TL, Quertermous T, Altshuler D, Seielstad M, Wong TY, Tai E-S, Feranil AB, Kuzawa CW, Adair LS, Herman A. Taylor J, Borecki IB, Gabriel SB, Wilson JG, Stefansson K, Thorsteinsdottir U, Gudnason V, Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall AR, Hegele RA, Kastelein JJP, Schadt EE, Rotter JI, Boerwinkle E, Strachan DP, Mooser V, Holm H, Reilly MP, Samani NJ, Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, Duijn CMv, Peltonen L, Abecasis GR, Boehnke M, Kathiresan S. Biological, clinical, and population relevance of 95 loci mapped for serum lipid concentrations. Nature. 466: 707-13

626    Teupser D, Baber R, Ceglarek U, Scholz M, Illig T, Gieger C, Holdt LM, Leichtler A, Greiser KH, Huster D, Linsel-Nitschke P, Schäfer A, Braund PS, Tiret L, Stark K, Raaz-Schrauder D, Fiedler GM, Wilfert W, Beutner F, Gielen S, Großhennig A, König IR, Lichtner P, Heid IM, Kluttig A, El Mokhtari NE, Rubin D, Ekici AB, Reis A, Garlichs C, Hall AS, Matthes G, Wittekind C, Hengstenberg C, Cambien F, Schreiber S, Werdan K, Meitinger T, Löffler M, Samani NJ, Erdmann J, Wichmann HE, Schunkert H, Thiery J. Genetic Regulation of Serum Phytosterol Levels and Risk of Coronary Artery Disease.  Circ Cardiovasc Genet. 2010 Aug;3(4):331-9. Epub 2010 Jun 7

625    Tews D, Fischer-Posovszky P, Wabitsch M. FTO - Friend or foe? Horm Metab Res. 2010 Feb;42(2):75-80.

624    The GABRIEL consortium (incl. Lee YA, Esparza-Gordillo J, Marenholz I). A GABRIEL Consortium Large-Scale Genome-Wide Association Study of Asthma. N Engl J Med. 2010.

623    Thier S, Lorenz D, Nothnagel M, Stevanin G, Dürr A, Nebel A, Schreiber S, Kuhlenbäumer G, Deuschl G, Klebe S. LINGO1 polymorphisms are associated with essential tremor in Europeans. Mov Disord. 2010 Mar 22. [Epub ahead of print]

622    Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, MägiR, Keskitalo K, Gudjonsdottir IH, Gretarsdottir S, Stefansson H, Thompson JR, Aulchenko YS, Nelis M, Aben KK, den Heijer M, Dirksen A, Ashraf H, Soranzo N, Valdes AM, Steves C, Uitterlinden AG, Hofman A, Tönjes A, Kovacs P, Hottenga JJ, Willemsen G, Vogelzangs N, Döring A, Dahmen N, Nitz B, Pergadia ML, Saez B, De Diego V, Lezcano V, Garcia-Prats MD, Ripatti S, Perola M, Kettunen J, Hartikainen AL, Pouta A, Laitinen J, Isohanni M, Huei-Yi S, Allen M, Krestyaninova M, Hall AS, Jones GT, van Rij AM, Mueller T, Dieplinger B, Haltmayer M, Jonsson S,Matthiasson SE, Oskarsson H, Tyrfingsson T, Kiemeney LA, Mayordomo JI, Lindholt JS, Pedersen JH, Franklin WA, Wolf H, Montgomery GW, Heath AC, Martin NG, Madden PA, Giegling I, Rujescu D, Järvelin MR, Salomaa V, Stumvoll M, Spector TD, Wichmann HE, Metspalu A, Samani NJ, Penninx BW, Oostra BA, Boomsma DI, Tiemeier H, van Duijn CM, Kaprio J, Gulcher JR; ENGAGE Consortium, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K. Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet. 2010 May;42(5):448-53. Epub 2010 Apr25. PubMed PMID: 20418888.

621    Thye T, Ehmen C, Intemann CD, Chinbuah MA, Ziegler A, Horstmann RD, Meyer CG. Rare human IFNG variants. J Interferon Cytokine Res. 2010 Apr;30(4):219-22.

620    Thye T, Vannberg FO, Wong SH, Owusu-Dabo E, Osei I, Gyapong J, Sirugo G, Sisay-Joof F, Enimil A, Chinbuah MA, Floyd S, Warndorff DK, Sichali L, Malema S, Crampin AC, Ngwira B, Teo YY, Small K, Rockett K, Kwiatkowski D, Fine PE, Hill PC, Newport M, Lienhardt C, Adegbola RA, Corrah T, Ziegler A; African TB Genetics Consortium; Wellcome Trust Case Control Consortium, Morris AP, Meyer CG, Horstmann RD, Hill AV. Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2.Nat Genet. 2010 Sep;42(9):739-41.

619    Timmermann B, Kerick M, Roehr C, Fischer A, Isau M, Boerno ST, Wunderlich A, Barmeyer C, Seemann P, Koenig J, Lappe M, Kuss AW, Garshasbi M, Bertram L, Trappe K, Werber M, Herrmann BG, Zatloukal K, Lehrach H, Schweiger MR. Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. PLoS One. 2010 Dec 22;5(12):e15661.

618    Tocchetti A, Soppo CB, Zani F, Bianchi F, Gagliani MC, Pozzi B, Rozman J, Elvert R, Ehrhardt N, Rathkolb B, Moerth C, Horsch M, Fuchs H, Gailus-Durner V, Beckers J, Klingenspor M, Wolf E, Hrabé de Angelis M, Scanziani E, Tacchetti C, Scita G, Di Fiore PP, Offenhäuser N. Loss of the actin remodeler Eps8 causes intestinal defects and improved metabolic status in mice. PLoS One. 2010 Mar 2;5(3):e9468. PMID: 20209148

617    Tölle M, Schuchardt M, Wiedon A, Huang T, Klöckel L, Jankowski J, Jankowski V, Zidek W, van der Giet M. Differential effects of uridine adenosine tetraphosphate on purinoceptors in the rat isolated perfused kidney.Br J Pharmacol. 2010 Oct;161(3):530-40

616    Tomlinson IP, Dunlop M, Campbell H, Zanke B, Gallinger S, Hudson T, Koessler T, Pharoah PD, Niittymäki I, Tuupanen S, Aaltonen LA, Hemminki K, Lindblom A, Försti A, Sieber O, Lipton L, van Wezel T, Morreau H, Wijnen JT, Devilee P, Matsuda K, Nakamura Y, Castellví-Bel S, Ruiz-Ponte C, Castells A, Carracedo A, Ho JW, Sham P, Hofstra RM, Vodicka P, Brenner H, Hampe J, Schafmayer C, Tepel J, Schreiber S, Völzke H, Lerch MM, Schmidt CA, Buch S, Moreno V, Villanueva CM, Peterlongo P, Radice P, Echeverry MM, Velez A, Carvajal-Carmona L, Scott R, Penegar S, Broderick P, Tenesa A, Houlston RS. COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. Br J Cancer. 2010 Jan 19;102(2):447-54. doi 10.1038/sj.bjc.6605338.

615    Trümbach D, Graf C, Pütz B, Kühne C, Panhuysen M, Weber P, Holsboer F, Wurst W, Welzl G, Deussing JM. Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models. BMC Syst Biol. 2010 Nov 19;4:159.

614    Truong T, Hung RJ, Amos CI, Wu X, Bickeböller H, Rosenberger A, Sauter W, Illig T, Wichmann HE, Risch A, Dienemann H, Kaaks R, Yang P, Jiang R, Wiencke JK, Wrensch M, Hansen H, Kelsey KT, Matsuo K, Tajima K, Schwartz AG, Wenzlaff A, Seow A, Ying C, Staratschek-Jox A, Nürnberg P, Stoelben E, Wolf J, Lazarus P, Muscat JE, Gallagher CJ, Zienolddiny S, Haugen A, van der Heijden HF, Kiemeney LA, Isla D, Mayordomo JI, Rafnar T, Stefansson K, Zhang ZF, Chang SC, Kim JH, Hong YC, Duell EJ, Andrew AS, Lejbkowicz F, Rennert G, Müller H, Brenner H, Le Marchand L, Benhamou S, Bouchardy C, Teare MD, Xue X, McLaughlin J, Liu G, McKay JD, Brennan P, Spitz MR. Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.. J Natl Cancer Inst. 2010 Jul 7;102(13):959-71. Epub 2010 Jun 14.

613    Tsolakidou A, Czibere L, Putz B, Trumbach D, Panhuysen M, Deussing JM, Wurst W, Sillaber I, Landgraf R, Holsboer F, Rein T. Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including Amyloid beta Precursor Protein. BMC Genomics. 2010 Oct 8;11:546.

612    Uebachs, M., Opitz, T., Royeck, M., Dickhof, G., Horstmann, M.-T., Isom, L., Beck, H. Efficacy loss of the anticonvulsant carbamazepine in mice lacking sodium channel accessory subunits via paradoxical effects on persistent sodium currents. J. Neurosci., 30: 8489-501

611    Uhlmann S, Zhang JD, Mannsperger H, Schwäger A, Ward A, Burmester S, Riazalhosseini Y, Korf U, Wiemann S, Sahin Ö. miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer. Oncogene 29: 4297-4306.

610    Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L, Adams LJ, Vengeliene V, Spanagel R, George DT, Hommer D, Heilig M. Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry, 67:1069-77 (14.273)

609    Unschuld PG, Ising M, Roeske D, Erhardt A, Specht M, Kloiber S, Uhr M, Müller-Myhsok B, Holsboer F, Binder EB. Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response. Neuropsychopharmacology. 2010 Jun;35(7):1583-92. doi:10.1038/npp.2010.30

608    van Bürck L, Blutke A, Kautz S, Rathkolb B, Klaften M, Wagner S, Kemter E, Hrabé de Angelis M, Wolf E, Aigner B, Wanke R, Herbach N. Phenotypic and pathomorphological characteristics of a novel mutant mouse model for maturity-onset diabetes of the young type 2 (MODY 2). Am J Physiol Endocrinol Metab. 298(3):E512-23. doi:10.1152/ajpendo.00465.2009

607    Vassos E, Collier DA, Holden S, Patch C, Rujescu D, St Clair D, Lewis CM. Penetrance for copy number variants associated with schizophrenia. Hum Mol Genet. Sep 1;19(17):3477-81.

606    Vegiopoulos A, Müller-Decker K, Strzoda D, Schmitt I, Chichelnitskiy E, Ostertag A, Berriel Diaz M, Rozman J, Hrabe de Angelis M, Nüsing RM, Meyer CW, Wahli W, Klingenspor M, Herzig S. Cyclooxygenase-2 controls energy homeostasis in mice by de novo recruitment of brown adipocytes. Science. 2010 May 28;328(5982):1158-61.

605    Vengeliene V, Leonardi-Essmann F, Marston H, Sommer W, Spanagel R. Glycine Transporter-1 Blockade Leads to Persistently Reduced Relapse-Like Alcohol Drinking in Rats. Biol Psychiatry, 68:704-11 (8.926)

604    Vermeulen M*, H. Christian Eberl*, Filomena Materese*, Hendrik Marks, Sergei Denissov, Falk Butter, Kenneth K Lee, Jesper V Olsen, Anthony A Hyman, Henk G Stunnenberg and Matthias Mann. Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers. Cell. 2010 Sep 17;142(6):967-80. doi:10.1016/j.cell.2010.08.020

603    Versini A, Ramoz N, Le Strat Y, Scherag S, Ehrlich S, Boni C, Hinney A,Hebebrand J, Romo L, Guelfi JD, Gorwood P. Estrogen receptor 1 gene (ESR1) is associated with restrictive anorexia nervosa. Neuropsychopharmacology. 2010 Jul;35(8):1818-25. Epub 2010 Apr 7. PubMed PMID: 20375995.

602    Vidigal JA, Morkel M, Wittler L, Brouwer-Lehmitz A, Grote P, Macura K, Herrmann BG. An inducible RNA interference system for the functional dissection of mouse embryogenesis. Nucleic Acids Res. 2010 Mar 28. [Epub ahead of print]

601    Vinayagam A, Stelzl U, Wanker EE. Repeated two-hybrid screening detects transient protein-protein interactions. Theoretical Chemistry Accounts 125 (3-6): 613-619 (2010-03).

600    Vintonyak, V.V., K. Warburg, H. Kruse, S. Grimme, K. Hübel, D. Rauh and H. Waldmann. Identification of Spiro-fused Indolin-2-one-thiazolidinones as Potent and Selective Inhibitors of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B, Angew Chem Int Ed Engl, 2010, 49(34):5902-5

599    Voight BF, Scott LJ, Steinthorsdottir V, Morris AP, Dina C, Welch RP, Zeggini E, Huth C, Aulchenko YS, Thorleifsson G, McCulloch LJ, Ferreira T, Grallert H, Amin N, Wu G, Willer CJ, Raychaudhuri S, McCarroll SA, Langenberg C, Hofmann OM, Dupuis J, Qi L, Segrè AV, van Hoek M, Navarro P, Ardlie K, Balkau B, Benediktsson R, Bennett AJ, Blagieva R, Boerwinkle E, Bonnycastle LL, Bengtsson Boström K, Bravenboer B, Bumpstead S, Burtt NP, Charpentier G, Chines PS, Cornelis M, Couper DJ, Crawford G, Doney AS, Elliott KS, Elliott AL, Erdos MR, Fox CS, Franklin CS, Ganser M, Gieger C, Grarup N, Green T, Griffin S, Groves CJ, Guiducci C, Hadjadj S, Hassanali N, Herder C, Isomaa B, Jackson AU, Johnson PR, Jørgensen T, Kao WH, Klopp N, Kong A, Kraft P, Kuusisto J, Lauritzen T, Li M, Lieverse A, Lindgren CM, Lyssenko V, Marre M, Meitinger T, Midthjell K, Morken MA, Narisu N, Nilsson P, Owen KR, Payne F, Perry JR, Petersen AK, Platou C, Proença C, Prokopenko I, Rathmann W, Rayner NW, Robertson NR, Rocheleau G, Roden M, Sampson MJ, Saxena R, Shields BM, Shrader P, Sigurdsson G, Sparsø T, Strassburger K, Stringham HM, Sun Q, Swift AJ, Thorand B, Tichet J, Tuomi T, van Dam RM, van Haeften TW, van Herpt T, van Vliet-Ostaptchouk JV, Walters GB, Weedon MN, Wijmenga C, Witteman J, Bergman RN, Cauchi S, Collins FS, Gloyn AL, Gyllensten U, Hansen T, Hide WA, Hitman GA, Hofman A, Hunter DJ, Hveem K, Laakso M, Mohlke KL, Morris AD, Palmer CN, Pramstaller PP, Rudan I, Sijbrands E, Stein LD, Tuomilehto J, Uitterlinden A, Walker M, Wareham NJ, Watanabe RM, Abecasis GR, Boehm BO, Campbell H, Daly MJ, Hattersley AT, Hu FB, Meigs JB, Pankow JS, Pedersen O, Wichmann HE, Barroso I, Florez JC, Frayling TM, Groop L, Sladek R, Thorsteinsdottir U, Wilson JF, Illig T, Froguel P, van Duijn CM, Stefansson K, Altshuler D, Boehnke M, McCarthy MI; MAGIC investigators; GIANT Consortium. "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis." Nat Genet. 2010 Jul;42(7):579-89.

598    Von Bubnoff N, Duyster J. Chronic myelogenous leukemia: treatment and monitoring. Dtsch Arztebl Int. 2010 Feb;107(7):114-21.

597    von Engelhardt J, Mack V, Sprengel R, Kavenstock N, Li KW, Stern-Bach Y, Smit AB, Seeburg PH, Monyer H. CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus. Science 327:1518-1522.

596    von Kampen O, Lipinski S, Till A, Martin SJ, Nietfeld W, Lehrach H, Schreiber S, Rosenstiel P. The caspase recruitment domain-containing protein 8 (CARD8) negatively regulates NOD2-mediated signaling. J Biol Chem. 2010 Apr 12. [Epub ahead of print]

595    Von Spiczak S, Muhle H, Helbig I, de Kovel CG, Hampe J, Gaus V, Koeleman BP, Lindhout D, Schreiber S, Sander T, Stephani U. Association Study of TRPC4 as a Candidate Gene for Generalized Epilepsy with Photosensitivity. Neuromolecular Med. 2010 Sep;12(3):292-9. Epub 2010 Jun 24

594    Wagener A, Goessling HF, Schmitt AO, Mauel S, Gruber AD, Reinhardt R, Brockmann GA. Genetic and diet effects on Ppar-alpha and Ppar-gamma signaling pathways in the Berlin Fat Mouse Inbred line with genetic predisposition for obesity. Lipids. Health. Dis. 2010; 9(1):99

593    Wagner S, Calzada-Wack J, Rosemann M, Becker L, Tost M, Silva-Buttkus P, Klein-Rodewald T, Fuchs H, Neff F, Hrabé de Angelis M, Esposito I. Characterization of ENU-mutant mice. Animal models for human diseases using morphological and molecular methods. Pathologe. 2010 Oct;31 Suppl 2:147-52. German. doi 10.1007/s00292-010-1347-5

592    Waha A, Felsberg J, Hartmann W, von dem Knesebeck A, Mikeska T, Joos S, Wolter M, Koch A, Yan PS, Endl E, Wiestler OD, Reifenberger G, Pietsch T, Waha A. Epigenetic Downregulation of Mitogen-Activated Protein Kinase Phosphatase MKP-2 Relieves Its Growth Suppressive Activity in Glioma Cells. Cancer Res. 2010 Feb 15;70(4):1689-1699. Epub 2010 Feb 2.

591    Walker RM, Christoforou A, Thomson PA, McGhee KA, Maclean A, Mühleisen TW, Strohmaier J, Nieratschker V, Nöthen MM, Rietschel M, Cichon S, Morris SW, Jilani O, Stclair D, Blackwood DH, Muir WJ, Porteous DJ, Evans KL. Association analysis of Neuregulin 1 candidate regions in schizophrenia and bipolar disorder. Neurosci Lett. 2010 Jun 30;478(1):9-13. Epub 2010 May 7.

590    Walter T, Held M, Neumann B, Heriche JK, Conrad C, Pepperkok R, Ellenberg J. Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imaging. J Struct Biol 170: 1-9.

589    Walters JT, Corvin A, Owen MJ, Williams H, Dragovic M, Quinn EM, Judge R, Smith DJ, Norton N, Giegling I, Hartmann AM, Möller HJ, Muglia P, Moskvina V, Dwyer S, O'Donoghue T, Morar B, Cooper M, Chandler D, Jablensky A, Gill M, Kaladjieva L, Morris DW, O'Donovan MC, Rujescu D, Donohoe G. Psychosis susceptibility gene ZNF804A and cognitive performance in schizophrenia. Arch Gen Psychiatry. Jul;67(7):692-700.

588    Wang Y; Liska F; Gosele C; Sedova L; Kren V; Krenova D; Ivics Z; Huebner N; Izsvak Z. A novel active endogenous retrovirus family contributes to genome variability in rat inbred strains. Genome Research 20 (1): 19-27 (2010) 

587    Weber YG, Lerche H. Genetische Befunde bei Epilepsien und ihre Konsequenzen für die Behandlung. Nervenheilkunde 2010

586    Weidinger S, Baurecht H, Naumann A, Novak N. Genome-wide association studies on IgE regulation: are genetics of IgE also genetics of atopic disease? Curr Opin Allergy Clin Immunol. 2010 Oct;10(5):408-17

585    Weintz G, Olsen JV, Frühauf K, Niedzielska M, Amit I,Jantsch J, Mages J, Frech C, Dölken L, Mann M, Lang R. The Phosphoproteome of Toll-like Receptor (TLR)-Activated Macrophages, Molecular Systemsbiology,accepted 4/2010

584    Weiss, J., M. Sos*, D. Seidel, M. Peifer, T. Zander, J. Heuckmann, R. Ullrich, R. Menon, S. Maier, A. Soltermann, H. Moch, P. Wagener, F. Fischer, S. Heynck, M. Koker, J. Schöttle, F. Leenders, F. Gabler, I. Dabow, S. Querings, L. Heukamp, H. Balke-Want, S. Ansén, D. Rauh, I. Baessmann, J. Altmüller, Z.Wainer, M. Conron, G. Wright, B. Solomon, E. Brambilla, C. Brambilla, P. Lorimier, S. Solberg, O. T. Brustgun, W. Engel-Riedel, C. Ludwig, I. Petersen, J. Sänger, J. Clement, H. Groen, W. Timens, H. Sietsma, E. Thunnissen, E. Smit, D. Heideman, F. Cappuzzo, C. Ligorio, S. Damiani, R. Beroukhim, W. Pao, B. Klebl, M. Baumann, R. Buettner, K. Ernestus, E. Stoelben, J. Wolf, P. Nürnberg, S. Perner, R. Thomas. Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous-cell lung cancer, Sci Transl Med, 2010, 2(62):62-9

583    Wellmann S, Truss M, Bruder E, Tornillo L, Zelmer A, Seeger K, Bührer C. The RNA-binding protein RBM3 is required for cell proliferation and protects against serum deprivation-induced cell death.  Pediatr Res. 2010 Jan;67(1):35-41.

582    Wendt N, Schulz A, Qadri F, Bolbrinker J, Kossmehl P, Winkler K, Stoll M, Vetter R, Kreutz R. Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol.Cardiovasc Res 2009;15;81:618-626

581    Wetzel, S., W. Wilk, S. Chammaa, B. Sperl, A. Roth, A. Yektaoglu, S. Renner, T. Berg, C. Arenz, A. Giannis, T.I. Oprea, D. Rauh, M. Kaiser, H. Waldmann, A. Scaffold-Tree-Merging Strategy for Prospective Bioactivity Annotation of gamma-Pyrones, Angew Chem Int Ed Engl, 2010, 49(21):3666-70

580    Wichmann C, Becker Y, Chen-Wichmann L, Vogel V, Vojtkova A, Herglotz J, Moore S, Koch J, Lausen J, Mäntele W, Gohlke H, Grez M. Dimer-tetramer transition controls RUNX1/ETO leukemogenic activity. Blood. 2010 Jul 29;116(4):603-13.

579    Wichmann C, Grez M, Lausen J. Molecular targeting of leukemic transcription factors: Strate-gies for RUNX1/ETO. Curr Drug Targets. 2010 Sep;11(9):1181-91. Review.

578    Widiker S, Kärst S, Wagener A, Brockmann GA. High-fat diet feeding leads to a decreased methylation of Mc4r gene in the obese BFMI and the lean B6 mouse lines. J. Appl. Genet. 2010; 51(2): 193-197

577    Wiebusch L and Hagemeier C. p53- and p21-dependent premature APC/C-Cdh1 activation in G2 is part of the long-term response to genotoxic stress. Oncogene 2010 Apr 12. [Epub ahead of print]

576    Will R, Eden M, Just S, Hansen A, Eder A, Frank D, Kuhn C, Seeger TS, Oehl U, Wiemann S, Korn B, Koegl M, Rottbauer W, Eschenhagen T, Katus HA, Frey N. Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing. Circ Res. 2010 Sep 16. [Epub ahead of print]

575    Williams HJ, Norton N, Dwyer S, Moskvina V, Nikolov I, Carroll L, Georgieva L, Williams NM, Morris DW, Quinn EM, Giegling I, Ikeda M, Wood J, Lencz T, Hultman C, Lichtenstein P, Thiselton D, Maher BS; Molecular Genetics of Schizophrenia Collaboration (MGS) International Schizophrenia Consortium (ISC), SGENE-plus, GROUP, Malhotra AK, Riley B, Kendler KS, Gill M, Sullivan P, Sklar P, Purcell S, Nimgaonkar VL, Kirov G, Holmans P, Corvin A, Rujescu D, Craddock N, Owen MJ, O'Donovan MC. Fine mapping of ZNF804A and genome-wide significant evidence for its involvement in schizophrenia and bipolar disorder. Mol Psychiatry. Apr 6

574    Wimmer VC, Reid CA, Mitchell S, Richards KL, Scaf BB, Leaw BT, Hill EL, Royeck M, Horstmann MT, Cromer BA, Davies PJ, Xu R, Lerche H, Berkovic SF, Beck H, Petrou S. Axon initial segment dysfunction in a mouse model of human geneticepilepsy with febrile seizures plus. J Clin Invest 2010 Aug 2;120(8):2661-71. doi: 10.1172/JCI42219. Epub 2010 Jul 12.

573    Winklhofer, K.F. and Haass, C. Mitochondrial dysfunction in Parkinson's disease. Biochim Biophys Acta, 1802, 29-44.

572    Wittig M, Helbig I, Schreiber S, Franke A. CNVineta: a data mining tool for large case-control copy number variation datasets. Bioinformatics. 2010 Sep 1;26(17):2208-9. Epub 2010 Jul 6.

571    Wittkop T, Emig D, Lange S, Rahmann S, Albrecht M, Morris JH, Böcker S, Stoye J, Baumbach J. Partitioning biological data with transitivity clustering. Nat Methods. 2010 Jun;7(6):419-20.

570    Wolff C, Malinowsky K, Berg D, Schragner K, Schuster T, Walch A, Bronger H, Höfler H, Becker KF. Signalling networks associated with urokinase-type plasminogen activator (uPA) and its inhibitor PAI-1 in breast cancer tissues: new insights from protein microarray analysis. J Pathol. 2010 Sep 27. [Epub ahead of print]

569    Wrzodek C, Schröder A, Dräger A, Wanke D, Berendzen KW, Kronfeld M, Harter K, and Zell A. ModuleMaster: a new tool to decipher transcriptional regulatory networks. Biosystems. 2010 Jan; 99(1):79-81. doi 10.1016/j.biosystems.2009.09.005

568    Wu H, Haist V, Baumgärtner W, Schughart K. Sustained viral load and late death in Rag2-/- mice after influenza A virus infection. Virol J. 2010 Jul 28;7:172-77. PMID: 20667098

567    Wurst W, Hrabe de Angelis M. Systematic phenotyping of mouse mutants. Nat Biotechnol. 28(7):684-5. doi:10.1038/nbt0710-684

566    Yasuno K, Bilguvar K, Bijlenga P, Low SK, Krischek B, Auburger G, Simon M,Krex D, Arlier Z, Nayak N, Ruigrok YM, Niemelä M, Tajima A, von Und Zu Fraunberg M, Dóczi T, Wirjatijasa F, Hata A, Blasco J, Oszvald A, Kasuya H, Zilani G,Schoch B, Singh P, Stüer C, Risselada R, Beck J, Sola T, Ricciardi F, Aromaa A,Illig T, Schreiber S, van Duijn CM, van den Berg LH, Perret C, Proust C, Roder C,Ozturk AK, Gaál E, Berg D, Geisen C, Friedrich CM, Summers P, Frangi AF, StateMW, Wichmann HE, Breteler MM, Wijmenga C, Mane S, Peltonen L, Elio V, SturkenboomMC, Lawford P, Byrne J, Macho J, Sandalcioglu EI, Meyer B, Raabe A, Steinmetz H, Rüfenacht D, Jääskeläinen JE, Hernesniemi J, Rinkel GJ, Zembutsu H, Inoue I,Palotie A, Cambien F, Nakamura Y, Lifton RP, Günel M. Genome-wide associationstudy of intracranial aneurysm identifies three new risk loci. Nat Genet. 2010 Apr 4.

565    Yin R, Tian F, Frankenberger B, de Angelis MH, Stoeger T. Selection and evaluation of stable housekeeping genes for gene expression normalization in carbon nanoparticle-induced acute pulmonary inflammation in mice. Biochem Biophys Res Commun. 2010 Sep 3;399(4):531-6. Epub 2010 Aug 1.

564    Zeller T, Wild P, Szymczak S, Rotival M, Schillert A, Castagne R, Maouche S, Germain M, Lackner K, Rossmann H, Eleftheriadis M, Sinning CR, Schnabel RB, Lubos E, Mennerich D, Rust W, Perret C, Proust C, Nicaud V, Loscalzo J, Hübner N, Tregouet D, Münzel T, Ziegler A, Tiret L, Blankenberg S, Cambien F. Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.PLoS One. 2010 May 18;5(5):e10693.

563    Zhu J.Y., Strehle M., Frohn A., Kremmer E., Höfig K.P., Meister G. & Adler H. Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68. J. Virol., 84(19): 10266-75.

562    Zweier M, Gregor A, Zweier C, Engels H, Sticht H, Wohlleber E, Bijlsma EK, Holder SE, Zenker M, Rossier E, Grasshoff U, Johnson DS, Robertson L, Firth HV, Kraus C, Ekici AB, Reis A, Rauch A. Mutations in MEF2C from the 5q14.3q15 microdeletion syndrome region are a frequent cause of severe mental retardation and diminish MECP2 expression. Hum Mutat. 2010 Jun;31(6):722-33.

2009

561    Abe K, Klaften M, Narita A, Kimura T, Imai K, Kimura M, Rubio-Aliaga I, Wagner S, Jakob T, Hrabé de Angelis M. Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice. Mamm Genome. 2009 Mar;20(3):152-61. DOI 10.1007/s00335-009-9170-0

560    Abou Jamra R, Georgi A, Suliman H, Klein K, Wolf Villela A, Schulze TG, Propping P, Cichon S, Rietschel M, Nöthen MM, Schumacher J. No association between the D-aspartate oxidase locus and schizophrenia. Psychiatr Genet. 2009 Feb;19. doi: 10.1097/YPG.0b013e328

559    Adler H., S. El-Gogo, K. Freimüller, S. Guggemoos, W. Zimmermann, N. Beauchemin and Kammerer, R.: Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1. PLoS One, 4 (7) (2009): e6317. doi:10.1371/ journal.pone.0006317

558    Ahting U, Floss T, Uez N, Schneider-Lohmar I, Becker L, Kling E, Iuso A, Bender A, Hrabé de Angelis M, Gailus-Durner V, Fuchs H, Meitinger T, Wurst W, Prokisch H, Klopstock T. Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import. Biochim Biophys Acta. 2009 May;1787(5):371-6. DOI:10.1016/j.bbabio.2008.12.001

557    Aigner B, Rathkolb B, Klaften M, Sedlmeier R, Klempt M, Wagner S, Michel D, Mayer U, Klopstock T, Hrabé de Angelis M, Wolf E. Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models. Exp Physiol. 2009 Apr;94(4):412-21. DOI: 10.1113/expphysiol.2008.045864

556    Aigner B, Rathkolb B, Klempt M, Wagner S, Michel D, Hrabé de Angelis M, Wolf E. N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels. J Biomed Sci. 2009 Jun 8;16:53. doi:10.1186/1423-0127-16-53

555    Ammerpohl O, Martín-Subero JI, Richter J, Vater I, Siebert R. Hunting for the 5th base: Techniques for analyzing DNA methylation. Biochim Biophys Acta. 2009 Sep;1790(9):847-62.

554    Arlt A, Bauer I, Schafmayer C, Tepel J, Sebens-Müerköster S, Brosch M, Röder C, Kalthoff H, Hampe J, Moyer MP, Fölsch UR, Schäfer H. Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of Nuclear factor E2-related factor 2 (Nrf2). Oncogene 2009; 28(45):3983-96

553    Bacon C, Endris V, Rappold G. Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system. Jouranl of Comparative Neurology. 2009 Mar 10;513(2):224-36.

552    Baek YS, Haas S, Hackstein H, Bein G, Hernandez-Santana M, Lehrach H, Sauer S, Seitz H. BMC Immunol. 2009 Apr 2;10:18.

551    Bandi SR, Brandts C, Rensinghoff M, Grundler R, Tickenbrock L, Köhler G, Duyster J, Berdel WE, Müller-Tidow C, Serve H, Sargin B; Study Alliance Leukemias. E3 ligase-defective Cbl mutants lead to a generalized mastocytosis and myeloproliferative disease. Blood. 2009 Nov 5;114(19):4197-208.

550    Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature. 2009 Nov 5;462(7269):108-12

549    Bartz F, Kern L, Erz D, Zhu M, Gilbert D, Meinhof T, Wirkner U, Erfle H, Muckenthaler M, Pepperkok R, Runz H (2009) Identification of cholesterol-regulating genes by targeted RNAi screening. Cell Metab 2009 10: 63-75.

548    Bauer, A., Kleeff, J., Bier, M., Wirtz, M., Kayed, H., Esposito, I., Korc, M., Hafner, M., Hoheisel, J.D. & Friess, H. (2009). Identification of malignancy factors by analysing cystic tumours of the pancreas. Pancreatology 9, 34-44.

547    Bazhin AV, Dalke C, Willner N, Abschütz O, Wildberger HGH, Philippov PP, Dummer R, Graw J, Hrabé de Angelis M, Schadendorf D, Umansky V, Eichmüller SB. Cancer-retina antigens as potential paraneoplastic antigens in melanoma-associated retinopathy. Int. J. Cancer. 2009 Jan; 124(1):140-49. PMID: 18814277

546    Beck A, Heinz A. Biologie der Alkoholabhängigkeit. Spectrum Psychiatrie 2009, 4: 10-13.

545    Becker T, Flaquer A, Brockschmidt FF, Herold C, Steffens M. Evaluation of potential power gain with imputed genotypes in genome-wide association studies. Hum Hered. 2009;68(1):23-34.

544    Beckers J, Wurst W, Hrabé de Angelis M. Towards better mouse models: enhanced genotypes, systemic phenotyping and envirotype modelling. Nat Rev Genet. 2009 Jun;10(6):371-80. doi:10.1038/nrg2578

543    Begus-Nahrmann Y, Lechel A, Obenauf AC, Nalapareddy K, Peit E, Hoffmann E, Schlaudraff F, Liss B, Schirmacher P, Kestler H,Danenberg E, Barker N, Clevers H, Speicher MR, Rudolph KL. p53 deletion impairs clearance of chromosomal-instable stemcells in aging telomere-dysfunctional mice. Nature genetics. 2009 Oct; 41(10):1138-43. doi:10.1038/ng.426

542    Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB Sr, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, Rivadeneira F, Wang TJ, Eiríksdottir G, Levy D, Psaty BM, Li M, Chamberlain AM, Hofman A, Vasan RS, Harris TB, Rotter JI, Kao WH, Agarwal SK, Stricker BH, Wang K, Launer LJ, Smith NL, Chakravarti A, Uitterlinden AG, Wolf PA, Sotoodehnia N,Köttgen A, van Duijn CM, Meitinger T, Mueller M, Perz S, Steinbeck G, Wichmann HE, Lunetta KL, Heckbert SR, Gudnason V, Alonso A, Kääb S, Ellinor PT, Witteman JC. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009 Aug;41(8):879-81. Epub 2009 Jul 13

541    Birnbaum S, Ludwig KU, Reutter H, Herms S, Steffens M, Rubini M, Baluardo C, Ferrian M, Almeida de Assis N, Alblas MA, Barth S, Freudenberg J, Lauster C, Schmidt G, Scheer M, Braumann B, Bergé SJ, Reich RH, Schiefke F, Hemprich A, Pötzsch S, Steegers-Theunissen RP, Pötzsch B, Moebus S, Horsthemke B, Kramer FJ, Wienker TF, Mossey PA, Propping P, Cichon S, Hoffmann P, Knapp M, Nöthen MM, Mangold E. Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. Nat Genet. 2009 Apr;41(4):473-7.

540    Blankenburg H, Finn RD, Prli A, Jenkinson AM, Ramírez F, Emig D, SchelhornSE, Büch J, Lengauer T, Albrecht M. DASMI: exchanging, annotating and assessing molecular interaction data. Bioinformatics. 2009 May 15;25(10):1321-8.

539    Blankenburg H, Ramírez F, Büch J, Albrecht M. DASMIweb: online integration,analysis and assessment of distributed protein interaction data. Nucleic AcidsRes. 2009 Jul 1;37(Web Server issue):W122-8.

538    Bleeke M, Festa S, Huebener N, Landgraf C, Schraven B, Gerhard Gaedicke, Rudolf Volkmer, Holger N. LodeSystematic amino acid substitutions improved efficiency of GD2-peptide mimotope vaccination against neuroblastoma. EUROPEAN JOURNAL OF CANCER 4 5, 2009, 2915-2921.

537    Blüher M, Bashan N, Shai I, Harman-Boehm I, Tarnovscki T, Avinaoch E, Stumvoll M, Dietrich A, Klöting N, Rudich A. Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity. J Clin Endocrinol Metab. 2009 Jul;94(7):2507-15.

536    Blüher M. Fat Tissue and Long Life. Obes Facts. 2008;1(4):176-182.Blüher M. Adipose tissue dysfunction in obesity. Exp Clin Endocrinol Diabetes. 2009 Jun;117(6):241-50.

535    Böhme M, Grallert H, Klapper M, Gieger C, Fischer A, Heid I, Wichmann HE, Döring F, Illig T. Association between functional FABP2 promoter haplotypes and body mass index: Analyses of 8072 participants of the KORA cohort study.  Mol Nutr Food Res. 2009 Jan 20.

534    Bolze F, Klingenspor M. Mouse models for the central melanocortin system. Genes Nutr, 2009,  March 6, 2009.

533    Böttcher Y, Unbehauen H, Klöting N, Ruschke K, Körner A, Schleinitz D, Tönjes A, Enigk B, Wolf S, Dietrich K, Koriath M, Scholz GH, Tseng YH, Dietrich A, Schön MR, Kiess W, Stumvoll M, Blüher M, Kovacs P. Adipose tissue expression and genetic variants of the bone morphogenetic protein receptor 1A gene (BMPR1A) are associated with human obesity. Diabetes. 2009 Sep;58(9):2119-28.

532    Breitenbuecher F, Schnittger S, Grundler R, Markova B, Carius B, Brecht A, Duyster J, Haferlach T, Huber C, Fischer T. Identification of a novel type of ITD mutations located in nonjuxtamembrane domains of the FLT3 tyrosine kinase receptor. Blood. 2009 Apr 23;113(17):3889-90.

531    Brockmann GA, Tsaih S, Neuschl C, Churchill GA, Li R. Genetic factors contributing to obesity and body weight can act through mechanisms affecting muscle weight, fat weight or both. Physiol. Genomics. 2009; 36:114-126

530    Brosbøl-Ravnborg A, Hvas CL, Agnholt J, Dahlerup JF, Vind I, Till A, Rosenstiel P, Höllsberg P. Toll-like receptor-induced granulocyte-macrophage colony-stimulating factor secretion is impaired in Crohn's disease by nucleotide oligomerization domain 2-dependent and -independent pathways. Clin Exp Immunol. 2009 Mar;155(3):487-95.

529    Bubnoff N, Engh RA, Aberg E, Sänger J, Peschel C, Duyster J. FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro. Cancer Res. 2009 Apr 1;69(7):3032-41.

528    Bunck M, Czibere L, Horvath C, Graf C, Frank E, Kessler MS, Murgatroyd C, Müller-Myhsok B, Gonik M, Weber P, Pütz B, Muigg P, Panhuysen M, Singewald N, Bettecken T, Deussing JM, Holsboer F, Spengler D, Landgraf R. A hypomorphic vasopressin allele prevents anxiety-related behavior. PLoS One. 2009;4(4):e5129.  Epub 2009 Apr 9. PubMed PMID: 19357765; PubMed Central PMCID: PMC2663030.

527    Bundesministerium für Bildung und Forschung, ed. Was Alzheimer und Parkinson verbindet. In: Impulsgeber Lebenswissenschaften. Forschung für die Innovationen der Zukunft. Bielefeld: Bertelsmann 2009, p. 54.

526    Calabro A, Beissbarth T, Kuner R, Stojanov M, Benner A, Asslaber M, Ploner F, Zatloukal K, Samonigg H, Poustka A, Sültmann H. Effects of infiltrating lymphocytes and estrogen receptor on gene expression and prognosis in breast cancer. Breast Cancer Res Treat. 2009 Jul;116(1):69-77.

525    Capper D, Gaiser T, Hartmann C, Habel A, Mueller W, Herold-Mende C, von Deimling A, Siegelin MD; Stem-cell like glioma cells are resistant to TRAIL/Apo2L and exhibit silenced expression of caspase-8. Acta Neuropathol. 2009 Apr;117(4):445-56.

524    Capper D, Weißert S, Balss J, Habel A, Meyer J, Jäger D, Ackermann U, Tessmer C, Korshunov A, Zentgraf H, Hartmann C, von Deimling A. Characterization of R132H Mutation Specific IDH1 Antibody Binding in Brain Tumors. Brain Pathol. 2009 Oct 27 [Epub ahead of print].

523    Capper D, Zentgraf H, Balss J, Hartmann C, von Deimling A. Monoclonal antibody specific for IDH1 R132H mutation. Acta Neuropathol. 2009 Oct 2. [Epub ahead of print].

522    Chan S, Romieu G, Huober J, Delozier T, Tubiana-Hulin M, Schneeweiss A, Lluch A, Llombart A, du Bois A, Kreienberg R, Mayordomo JI, Antón A, Harrison M, Jones A, Carrasco E, Vaury AT, Frimodt-Moller B, Fumoleau P. Phase III study of gemcitabine plus docetaxel compared with capecitabine plus docetaxel for anthracycline-pretreated patients with metastatic breast cancer. J Clin Oncol. 2009 Apr 10;27(11):1753-60. Epub 2009 Mar 9.

521    Chaurasia G, Malhotra S, Russ J, Schnoegl S, Hänig C, Wanker EE, Futschik Me. UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome. Nucl. Acids Res. 2009 Jan; 37 (suppl_1):D657-660. doi 10.1093/nar/gkn841

520    Chavez L, Bais AS, Vingron M, Lehrach H, Adjaye J, Herwig R. In silicoidentification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach. BMC Genomics. 2009 Jul 15; 10: 314.

519    Chioza BA, Aicardi J, Aschauer H, Brouwer O, Callenbach P, Covanis A, Dooley JM, Dulac O, Durner M, Eeg-Olofsson O, Feucht M, Friis ML, Guerrini R, Kjeldsen MJ, Nabbout R, Nashef L, Sander T, Sirén A, Wirrell E, McKeigue P, Robinson R, Gardiner RM, Everett KV. Genome wide high density SNP-based linkage analysis of childhood absence epilepsy identifies a susceptibility locus on chromosome 3p23-p14. Epilepsy Res. 2009 Dec;87(2-3):247-55. Epub 2009 Oct 17.

518    Chirasani SR, Markovic DS, Synowitz M, Eichler SA, Wisniewski P, Kaminska B, Otto A, Wanker E, Schäfer M, Chiarugi P, Meier JC, Kettenmann H, Glass R. Transferrin-receptor-mediated iron accumulation controls proliferation and glutamate release in glioma cells. Journal of Molecular Medicine (Berlin, Germany). 2009 Feb; 87 (2):153-167. doi 10.1007/s00109-008-0414-3

517    Cichon S, Craddock N, Daly M, Faraone SV, Gejman PV, Kelsoe J, Lehner T, Levinson DF, Moran A, Sklar P, Sullivan PF. Psychiatric GWAS Consortium Steering Committee, A framework for interpreting genome-wide association studies of psychiatric disorders. Mol Psychiatry. 2009 Jan;14(1):10-7. doi:10.1038/mp.2008.126

516    Cox A, Dumont BL, Ding Y, Bell JT, Brockmann GA, Bult C, Paigen B, Flint J, Churchill GA, Broman KW. A new standard genetic map for the laboratory mouse. Genetics. 2009; 182:1335-1344

515    Cox J, Matic I, Hilger M, Nagaraj N, Selbach M, Olsen JV, Mann M. A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics. Nature Protocols. 2009 Apr; 4(5):698-705. doi 10.1038/nprot.2009.36

514    Dahme, T., H.A. Katus, and W. Rottbauer. (2009). Fishing for the genetic basis of cardiovascular disease. Dis Model Mech 2:18-22.

513    Darvas M, Morsch M, Racz I, Ahmadi S, Swandulla D, Zimmer A (2009) Modulation of the Ca2+ conductance of nicotinic acetylcholine receptors by Lypd6. Eur Neuropsychopharmacol 19:670-681 doi:10.1016/j.euroneuro.2009.03.007

512    Dehghan A, Bis JC, Dupuis J, Barbalic M, Baumert J, Smith AV, Witteman JC, Harris T, Rotter JI, Nambi V, Koenig W, Benjamin EJ. Meta-analysis of Genome-wide Association Study in 26,967 Subjects of 6 Population-Based Studies Identifies 6 Loci for C-Reactive Protein Serum Levels: The Charge Consortium. doi:10.1161/CIRCULATIONAHA.109.191960

511    Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GD, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, McArdle WL, Lumley T, Pankow JS, Hofman A, Massaro JM, Rivadeneira F, Kolz M, Taylor KD, van Duijn CM, Kathiresan S, Illig T, Aulchenko YS, ..., Johnson AD, Uitterlinden AG, Tofler GH, Gieger C, Psaty BM, Boerwinkle E, Koenig W et al. Association of novel genetic loci with circulating fibrinogen levels. Circ Cardiovasc Genet 2009;2:125-133.

510    Di Benedetto B, Kallnik M, Vogt Weisenhorn DM, Falls WA, Wurst W, Hölter SM. (2009) Activation of ERK/MAPK in the lateral amygdala of the mouse is required for acquisition of a fear potentiated startle response. Neuropsychopharmacology 34:356-366

509    Di Benedetto B, Wefers B, Wurst W, Kühn R. Local knockdown of ERK2 in the adult mouse brain via adeno-associated virus-mediated RNA interference. Mol Biotechnol. 2009 Mar;41(3):263-9. Epub 2008 Dec 4. Erratum in: Mol Biotechnol. 2009 Mar;41(3):308. Benedetto, Barbara Di [corrected to Di Benedetto, Barbara]. PMID: 19052925 [PubMed - in process]

508    Dibbens LM, Mullen S, Helbig I, Mefford HC, Bayly MA, Bellows S, Leu C, Trucks H, Obermeier T, Wittig M, Franke A, Caglayan H, Yapici Z; EPICURE Consortium, Sander T, Eichler EE, Scheffer IE, Mulley JC, Berkovic SF. Familial and sporadic 15q13.3 microdeletions in idiopathic generalized epilepsy: precedent for disorders with complex inheritance. Hum Mol Genet. 2009 Oct 1;18(19):3626-31. Epub 2009 Jul 10. PMID: 19592580

507    Diehl-Schmid J, Grimmer T, Laws SM, Neumann M, Perneczky R,Riemenschneider M, Kurz A, Förstl H. [Frontotemporal lobar degeneration. Part 1: diagnosis and treatment]. Fortschr Neurol Psychiatr. 2009 Mar;77(3):169-76; quiz 177-9. Epub 2009 Mar 12. Review. German.

506    Diehl-Schmid J, Neumann M, Laws SM, Perneczky R, Grimmer T, Danek A, Kurz A, Riemenschneider M, Förstl H. [Frontotemporal lobar degeneration]. Fortschr Neurol Psychiatr. 2009 May;77(5):295-304. Epub 2009 Apr 1. Review. German.

505    Ditzen C, Varadarajulu J, Czibere L, Gonik M, Targosz BS, Hambsch B, Bettecken T, KeÃ?ler MS, Frank E, Bunck M, Teplytska L, Erhardt A, Holsboer F, Müller-Myhsok B, Landgraf R, Turck CW. Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways. Mol Psychiatry. 2009 Jan 13. [Epub ahead of print] PubMed PMID: 19139748.

504    Djarmati A, Hagenah J, Reetz K, Winkler S, Behrens MI, Pawlack H, Lohmann K, Ramirez A, Tadic V, Brüggemann N, Berg D, Siebner HR, Lang AE, Pramstaller PP, Binkofski F, Kostic VS, Volkmann J, Gasser T, Klein C. ATP13A2 variants in early-onset Parkinson?s disease patients and controls. Mov Disord 2009;24:2104-2111.

503    Dölken L, Jonjic S. All for one and one for all: herpesviral microRNAs closein on their prey. Cell Host Microbe. 2009 Apr 23;5(4):315-7. PubMed PMID:19380110.

502    Dölken L, Pfeffer S, Koszinowski UH. Cytomegalovirus microRNAs. Virus Genes.2009 Jun;38(3):355-64. Epub 2009 Mar 17. Review. PubMed PMID: 19291384.

501    Domschke C, Schuetz F, Ge Y, Seibel T, Falk C, Brors B, Vlodavsky I, Sommerfeldt N, Sinn HP, Kühnle MC, Schneeweiss A, Scharf A, Sohn C, Schirrmacher V, Moldenhauer G, Momburg F, Beckhove P. Intratumoral cytokines and tumor cell biology determine spontaneous breast cancer-specific immune responses and their correlation to prognosis. Cancer Res. 2009 Nov 1;69(21):8420-8. Epub 2009 Oct 20.

500    Dräger A, Planatscher H, Wouamba DM, Schröder A, Hucka M, Endler L, Golebiewski M, Müller W, and Zell A: SBML2LaTeX: Conversion of SBML files into human-readable reports, Bioinformatics 2009, (23 March 2009). doi:10.1186/1752-0509-3-67

499    Dressel R, Guan K, Nolte J, Elsner L, Monecke S, Nayernia K, Hasenfuss G, Engel W. Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules. Biol Direct 2009;4:31.

498    Drews E, Racz I, Lacava AD, Barth A, Bilkei-Gorzo A, Wienker TF, Zimmer A (2009) Quantitative trait loci contributing to physiological and behavioural ethanol responses after acute and chronic treatment. Int J Neuropsychopharmacol 13:155-169.

497    Drzezga A, Grimmer T, Henriksen G, Mühlau M, Perneczky R, Miederer I, Praus C, Sorg C, Wohlschläger A, Riemenschneider M, Wester HJ, Foerstl H, Schwaiger M, Kurz A. Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. Neurology. 2009 Apr 28;72(17):1487-94. Epub 2009 Apr 1.

496    Eckerle I, Muth D, Batzler J, Henrich KO, Lutz W, Fischer M, Witt O, Schwab M, Westermann F.Regulation of BIRC5 and ist isoform BIRC5-2B in neuroblastoma. Cancer Lett. 2009 Nov 18;285(1):99-107. Epub 2009 Jun 3

495    Eichbaum M, Bischofs E, Nehls K, Schneeweiss A, Sohn C. Bendamustine hydrochloride ? A renaissance of alkylating strategies in anticancer medicine. Drugs Today (Barc) 45:431-444, 2009.

494    Eichbaum MH, Weiss LM, Bruckner T, Schneeweiss A, Sinn HP, Gebauer G, Fersis N, Kussmaul
J, Sohn C. Prognostic impact of hemoglobin levels before and during carboplatin/taxane-based chemotherapy in patients with primary invasive epithelial ovarian cancer. Med Sci Monit 15:CR156-63, 2009.

493    El Sharawy A, Hundrieser B, Brosch M, Wittig M, Huse K, Platzer M, Becker A, Simon M, Rosenstiel P, Schreiber S, Krawczak M, Hampe J. Systematic evaluation of the effect of common SNPs on pre-mRNA splicing. Hum Mutat. 2009 Apr;30(4):625-32.

492    Elefsinioti A, Ackermann M, Beyer A. Accounting for redundancy when integrating gene interaction databases. PLoS One. 2009 Oct 22;4(10):e7492.

491    Ellinghaus D, Schreiber S, Franke A, Nothnagel M. Current software for genotype imputation. Hum Genomics. 2009 Jul;3(4):371-80

490    El-Maarri O, Kareta MS, Mikeska T, Becker T, Diaz-Lacava A, Junen J, Nüsgen N, Behne F, Wienker T, Waha A, Oldenburg J, Chédin F. A systematic search for DNA methyltransferase polymorphisms reveals a rare DNMT3L variant associated with subtelomeric hypomethylation. Hum Mol Genet. 2009 May 15;18(10):1755-68.

489    Elstner M, Morris CM, Heim K, Lichtner P, Bender A, Mehta D, Schulte C, Sharma M, Hudson G, Goldwurm S, Giovanetti A, Zeviani M, Burn DJ, McKeith IG, Perry RH, Jaros E, Kruger R, Wichmann HE, Schreiber S, Campbell H, Wilson JF, Wright AF, Dunlop M, Pistis G, Toniolo D, Chinnery PF, Gasser T, Klopstock T, Meitinger T, Prokisch H, Turnbull DM. Single-cell expression profiling of dopaminergic neurons combined with association analysis identifies pyridoxal kinase as Parkinson's disease gene. Ann Neurol. 2009 Jun 18;66(6):792-8.

488    Enard W, Gehre S, Hammerschmidt K, Hölter SM, Blass T, Somel M, Brückner MK, Schreiweis C, Winter C, Sohr R, Becker L, Wiebe V, Nickel B, Giger T, Müller U, Groszer M, Adler T, Aguilar Pimentel JA, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Favor J, Fuchs H, Gailus-Durner V, Hans W, Hölzlwimmer G, Javaheri A, Kalaydjiev S, Kallnik M, Kling E, Kunder S, Mossbrugger I, Naton B, Racz I, Rathkolb B, Rozman J, Schrewe A, Busch DH, Graw J, Ivandic B, Klingenspor M, Klopstock T, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, Zimmer A, Fisher SE, Morgenstern R, Arendt T, Hrabé de Angelis M, Fischer J, Schwarz J, Pääbo S. A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell. 2009 May 29;137(5):961-71. DOI 10.1016/j.cell.2009.03.041

487    End C, Bikker F, Renner M, Bergmann G, Lyer S, Blaich S, Hudler M, Helmke B, Gassler N, Autschbach F, Ligtenberg AJ, Benner A, Holmskov U, Schirmacher P, Nieuw Amerongen AV, Rosenstiel P, Sina C, Franke A, Hafner M, Kioschis P, Schreiber S, Poustka A, Mollenhauer J. DMBT1 functions as pattern-recognition molecule for poly-sulfated and poly-phosphorylated ligands. Eur J Immunol. 2009 Mar;39(3):833-42.

486    Endres K, Mitteregger G, Kojro E, Kretzschmar H, Fahrenholz F.Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo. Neurobiol Dis. 2009 Nov;36(2):233-41. Epub 2009 Jul 24.

485    Engels H, Wohlleber E, Zink A, Hoyer J, Ludwig KU, Brockschmidt FF, Wieczorek D, Moog U, Hellmann-Mersch B, Weber RG, Willatt L, Kreiss-Nachtsheim M, Firth HV, Rauch A. A novel microdeletion syndrome involving 5q14.3-q15: clinical and molecular cytogenetic characterization of three patients. Eur J Hum Genet. 2009 Dec;17(12):1592-1599. Epub 2009 May 27. PMID: 19471318 doi:10.1038/ejhg.2009.90

484    Erdmann J, Grosshennig A, Braund PS, König IR, Hengstenberg C, Hall AS, Linsel-Nitschke P, Kathiresan S, Wright B, Trégouët DA, Cambien F, Bruse P, Aherrahrou Z, Wagner AK, Stark K, Schwartz SM, Salomaa V, Elosua R, Melander O, Voight BF, O'Donnell CJ, Peltonen L, Siscovick DS, Altshuler D, Merlini PA, Peyvandi F, Bernardinelli L, Ardissino D, Schillert A, Blankenberg S, Zeller T, Wild P, Schwarz DF, Tiret L, Perret C, Schreiber S, El Mokhtari NE, Schäfer A, März W, Renner W, Bugert P, Klüter H, Schrezenmeir J, Rubin D, Ball SG, Balmforth AJ, Wichmann HE, Meitinger T, Fischer M, Meisinger C, Baumert J, Peters A, Ouwehand WH; Italian Atherosclerosis, Thrombosis, and Vascular Biology Working Group; Myocardial Infarction Genetics Consortium; Wellcome Trust Case Control Consortium; Cardiogenics Consortium, Deloukas P, Thompson JR, Ziegler A, Samani NJ, Schunkert H. New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet. 2009 Mar; 41(3):280-2.

483    Ernst A, Hofmann S, Ahmadi R, Becker N, Korshunov A, Engel F, Hartmann C, Felsberg J, Sabel M, Peterziel H, Durchdewald M, Hess J, Barbus S, Campos B, Starzinski-Powitz A, Unterberg A, Reifenberger G, Lichter P, Herold-Mende C, Radlwimmer B. Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival. Clin Cancer Res. 2009 Nov 1;15(21):6541-50. Epub 2009 Oct 27.

482    Esparza-Gordillo J, Weidinger S, Fölster-Holst R, Bauerfeind A, Ruschendorf F, Patone G, Rohde K, Marenholz I, Schulz F, Kerscher T, Hubner N, Wahn U, Schreiber S, Franke A, Vogler R, Heath S, Baurecht H, Novak N, Rodriguez E, Illig T, Lee-Kirsch MA, Ciechanowicz A, Kurek M, Piskackova T, Macek M, Lee YA, Ruether A. A common variant on chromosome 11q13 is associated with atopic dermatitis. Nat Genet. 2009 May;41(5):596-601. Epub 2009 Apr 6.

481    Esslinger C, Walter H, Kirsch P, Erk S, Schnell K, Arnold C, Haddad L, Mier D, Opitz von Boberfeld C, Raab K, Witt SH, Rietschel M, Cichon S, Meyer-Lindenberg A (2009) Neural mechanisms of a genome-wide significant psychosis variant. Science. 2009 May 1;324(5927):605. doi: 10.1126/science.1167768

480    Feil R, Hölter SM, Weindl K, Wurst W, Langmesser S, Gerling A, Feil S, Albrecht U. (2009) cGMP-dependent protein kinase I, the circadian clock, sleep, and learning. Commun Integr Biol 2:298-301

479    Feltrin E, Campanaro S, Diehl AD, Ehler E, Faulkner G, Fordham J, Gardin C, Harris M, Hill D, Knöll R, Laveder P, Mittempergher L, Nori A, Reggiani C, Sorrentino V, Volpe P, Zara I, Valle G, Deegan JNC. Muscle Research and Gene Ontology: New standards for improved data integration. BMC medical genomics. 2009 2(1):6.

478    Fenzl T, Flachskamm C, Rossbauer M, Deussing JM, Kimura M. Circadian rhythms of basal orexin levels in the hypothalamus are not influenced by an impaired corticotropin-releasing hormone receptor type 1 system. Behav Brain Res. 2009 Oct 12;203(1):143-135.

477    Filosa A, Paixão S, Honsek SD, Carmona MA, Becker L, Feddersen B, Gaitanos L, Rudhard Y, Schoepfer R, Klopstock T, Kullander K, Rose CR, Pasquale EB, Klein R. Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. Nat Neurosci. 2009 Oct;12(10):1285-92. Epub 2009 Sep 6.PMID: 19734893

476    Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U. Inactivation of the Fto gene protects from obesity. Nature. 2009 Apr 16;458(7240):894-8.

475    Flach B., B. Steer, N. N. Thakur, J. Haas and Adler, H.: The M10 locus of murine gammaherpesvirus 68 contributes to both the lytic and latent phases of infection. J. of Virology 83 (2009): 8163-8172

474    Flaquer A, Fischer C, Wienker TF (2009) A new sex-specific genetic map of the human pseudoautosomal regions (PAR1 and PAR2). Hum Hered 3:192-200

473    Fontaine J, Barbosa-Silva A, Schaefer M, Huska MR, Muro EM, Andrade-Navarro MA. MedlineRanker: flexible ranking of biomedical literature. Nucleic Acids Research 2009; 37:W141-W146. doi 10.1093/nar/gkp353

472    Fournier M, Vitte J, Garrigue J, Langui D, Dullin JP, Saurini F, Hanoun N, Perez-Diaz F, Cornilleau F, Joubert C, Ardila-Osorio H, Traver S, Duchateau R, Goujet-Zalc C, Paleologou K, Lashuel HA, Haass C, Duyckaerts C, Cohen-Salmon C, Kahle PJ, Hamon M, Brice A, Corti O. Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy. PLoS One. 2009 Aug 14;4(8):e6629.

471    Frank S, Copanaki E, Burbach G, Müller UC, Deller T (2009) Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice. Neurosci Lett 2009; 453: 41-4

470    Freese C, Garratt AN, Fahrenholz F, Endres K. The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1. FEBS  J. 2009 Mar; 276(6): 1568-1580. (doi 10.1111/j.1742-4658.2009.06889.x)

469    Freiwald A, Sauer S. Nature Protoc. 2009;4(5):732-42.

468    Friedel CC, Dölken L, Ruzsics Z, Koszinowski UH, Zimmer R. Conservedprinciples of mammalian transcriptional regulation revealed by RNA half-life. Nucleic Acids Res. 2009 Sep;37(17):e115. Epub 2009 Jun 26. PubMed PMID: 19561200;PubMed Central PMCID: PMC2761256.

467    Friedel CC, Dölken L. Metabolic tagging and purification of nascent RNA:implications for transcriptomics. Mol Biosyst. 2009 Nov;5(11):1271-8. Epub 2009Aug 26. Review. PubMed PMID: 19823741.

466    Friedrich P, Feulner TM, Laws SM, Eckart K, Perneczky R, Kurz A, Förstl H, Riemenschneider M. No association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer´s disease. Neurobiol Aging. 2009. [Epub ahead of print]

465    Friedrichs F, Zugck C, Rauch GJ, Ivandic B, Weichenhan D, Müller-Bardorff M, Meder B, El Mokhtari NE, Regitz-Zagrosek V, Hetzer R, Schäfer A, Schreiber S, Chen J, Neuhaus I, Ji R, Siemers NO, Frey N, Rottbauer W, Katus HA, Stoll M. HBEGF, SRA1, and IK: Three co-segregating genes as determinants of cardiomyopathy. Genome Res. 2009 Mar;19(3):395-403

464    Froehlich H, Sahin Ö, Arlt D, Bender C, Beissbarth T. Deterministic Effects Propagation Networks for Reconstructing Protein Signaling Networks from Multiple Interventions. BMC Bioinformatics, 2009, 10(10):R104.

463    Froehlich H, Tresch A, Beissbarth T. Nested Effects Models for Learning Signaling Networks from Perturbation Data. Biometrical Journal, 2009, 51(2):304-23.

462    Fromme T, Hoffmann C, Nau K, Rozman J, Reichwald K, Utting M, Platzer M, Klingenspor M. An intronic single base exchange leads to a brown adipose tissue specific loss of Ucp3 expression and an altered body mass trajectory. Physiol Genomics. 2009 Jun 10;38(1):54-62. doi:10.1152/physiolgenomics.00249.2007

461    Fuchs H, Gailus-Durner V, Adler T, Aguilar Pimentel JA, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Dalke C, Ehrhardt N, Fasnacht N, Ferwagner B, Frischmann U, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Maier H, Moßbrugger I, Mörth C, Naton B, Nöth U, Pasche B, Prehn C, Przemeck G, Puk O, Racz I, Rathkolb B, Rozman J, Schäble K, Schreiner R, Schrewe A, Sina C, Steinkamp R, Thiele F, Willershäuser M, Zeh R, Adamski J, Busch DH, Beckers J, Behrendt H, Daniel H, Esposito I, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Klingenspor M, Klopstock T, Lengeling A, Mempel M, Müller W, Neschen S, Ollert M, Quintanilla-Martinez L, Rosenstiel P, Schmidt J, Schreiber S, Schughart K, Schulz H, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M. The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. Curr Pharm Biotechnol. 2009 Feb;10(2):236-43. PMID: 19199957

460    Funke C, Soehn AS, Tomiuk J, Riess O, Berg D (2009) Genetic analysis of coding SNPs in blood-brain barrier transporter MDR1 in European Parkinson's disease patients. J Neural Transm 116(4):443-50

459    Funke C, Tomiuk J, Riess O, Berg D, Soehn AS (2009) Genetic analysis of heme oxygenase-1 (HO-1) in German Parkinson's disease patients.  J Neural Transm 116(7):853-9

458    Gaedcke J, Grade M, Jung K, Schirmer M, Jo P, Obermeyer C, Wolff HA, Herrmann MK, Beissbarth T, Becker H, Ried T, Ghadimi M. KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy. Radiother Oncol. 2009.

457    Galiveti CR, Rozhdestvensky TS, Brosius J, Lehrach H, Konthur Z (2010) Application of housekeeping npcRNAs for quantitative expression analysis of human transcriptome by real-time PCR. RNA 16:450-461. Epub 2009 Dec 29.

456    Gallinat J, Schubert F, Brühl R, Hellweg R, Klär AA, Kehrer C, Wirth C, Sander T, Lang UE (2010) Met carriers of BDNF Val66Met genotype show increased N-acetylaspartateconcentration in the anterior cingulate cortex. Neuroimage. 2010 Jan 1;49(1):767-71. Epub 2009 Aug 13.

455    Ganguly K, Depner M, Fattman C, Bein K, Oury TD, Wesselkamper SC, Borchers MT, Schreiber M, Gao F, von Mutius E, Kabesch M, Leikauf GD, Schulz H. Superoxide dismutase 3, extracellular (SOD3) variants and lung function. Physiological Genomics. 2009 May 13;37(3):260-7. Epub 2009 Mar 24. doi:10.1152/physiolgenomics.90363.2008.

454    Ganguly K, Upadhyay S, Irmler M, Takenaka S, Pukelsheim K, Beckers J, Hamelmann E, Schulz H, Stoeger T. Pathway focused protein profiling indicates differential function for IL-1B, -18 and VEGF during initiation and resolution of lung inflammation evoked by carbon nanoparticle exposure in mice. Particl and Fibre Toxicology 2009 Dec 2;6:31. doi:10.1186/1743-8977-6-31

453    García-Cazorla A, Wolf NI, Serrano M, Moog U, Pérez-Dueñas B, Póo P, Pineda M, Campistol J, Hoffmann GF. Mental retardation and inborn errors of metabolism. Journal of Inherited Metabolic Disease . 2009 Oct;32(5):597-608. Epub 2009 Aug 14.

452    Gasser T (2009) Molecular pathogenesis of Parkinson disease: insights from genetic studies. Expert Rev Mol Med 11:e22

451    George AJ, Gordon L, Beissbarth T, Koukoulas I, Holsinger DRM, Perreau V, Cappai R, Tan SS, Masters CL, Scott HS, Li QX. A Serial Analysis of Gene Expression (SAGE) profile of the Alzheimer's disease Tg2576 mouse model.  Neurotoxicity Research, Volume 17, Number 4, 360-379, DOI: 10.1007/s12640-009-9112-3.

450    Georgi A, Schumacher J, Leon CA, Wolf Villela A, Klein K, Böhenz KV, Schirmbeck F, Strohmaier J, Propping P, Schulze TG, Rietschel M, Nöthen MM, Cichon S, Abou Jamra R. No association between genetic variants at the DGCR2 gene and schizophrenia in a German sample. Psychiatr Genet. 2009 Apr;19(2):104. doi: 10.1097/YPG.0b013e328311874a

449    Getlik, M., Grutter, C., Simard, J.R., Kluter, S., Rabiller, M., Rode, H.B., Robubi, A., and Rauh, D. (2009). Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc. J Med Chem, 2009, 52, 3915-3926.

448    Gibson TJ. Cell regulation: determined to signal discrete cooperation. Trends Biochem Sci. 2009 Oct;34(10):471-82. Epub 2009 Sep 8.

447    Gipp, M., Marcus, G., Harder, N., Suratanee, A., Rohr, K., König, R. & Männer, R. (2009). Haralick's Texture Features Computed by GPUs for Biological Applications, IAENG International Journal of Computer Science, 2009, 36:1, IJCS_36_1_09.

446    Gispert S, Ricciardi F, Kurz A, Azizov M, Hoepken HH, Becker D, Voos W, Leuner K, Müller WE, Kudin AP, Kunz WS, Zimmermann A, Roeper J, Wenzel D, Jendrach M, García-Arencíbia M, Fernández-Ruiz J, Huber L, Rohrer H, Barrera M, Reichert AS, Rüb U, Chen A, Nussbaum RL, Auburger G.Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration. PLoS One. 2009 Jun 3;4(6):e5777.

445    Gloeckner CJ, Schumacher A, Boldt K, Ueffing M: The Parkinson disease-associated protein kinase LRRK2 exhibits MAPKKK activity and phosphorylates MKK3/6 and MKK4/7, in vitro.  J Neurochem. 2009 May;109(4):959-68.  doi 10.1111/j.1471-4159.2009.06024.x

444    Goehringer C, Rutschow D, Bauer R, Schinkel S, Weichenhan D, Bekeredjian R, Straub V, Kleinschmidt JA, Katus HA, Müller OJ. Prevention of cardiomyopathy in delta-sarcoglycan knockout mice after systemic transfer of targeted adeno-associated viral vectors. Cardiovasc Res. 2009 Jun 1;82(3):404-10. Epub 2009 Feb 13.

443    Gong Y, Yao E, Shen R, Goel A, Arcila M, Teruya-Feldstein J, Zakowski MF, Frankel S, Peifer M, Thomas RK, Ladanyi M, Pao W. High expression levels of total IGF-1R and sensitivity of NSCLC cells in vitro to an anti-IGF-1R antibody (R1507). PLoS One. 2009 Oct 6;4(10):e7273.

442    Grigoroiu-Serbanescu M, Herms S, Muhleisen TW, Georgi A, Diaconu CC, Strohmaier J, Czerski P, Hauser J, Leszczynska-Rodziewicz A, Jamra RA, Babadjanova G, Tiganov A, Krasnov V, Kapiletti S, Neagu AL, Vollmer J, Breuer R, Rietschel M, Propping P, Noethen MM, Cichon S.  Variation in P2RX7 candidate gene (rs2230912) is not associated with bipolar I disorder and unipolar major depression in four European samples. Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):1017-21. doi 10.1002/ajmg.b.30952

441    Grimmer T, Riemenschneider M, Förstl H, Henriksen G, Klunk WE, Mathis CA, Shiga T, Wester HJ, Kurz A, Drzezga A. Beta amyloid in Alzheimer´s disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid. Biol Psychiatry. 2009;65(11):927-34. [Epub 2009 Mar 6]

440    Grundler R, Brault L, Gasser C, Bullock AN, Dechow T, Woetzel S, Pogacic V, Villa A, Ehret S, Berridge G, Spoo A, Dierks C, Biondi A, Knapp S, Duyster J, Schwaller J. Dissection of PIM serine/threonine kinases in FLT3-ITD-induced leukemogenesis reveals PIM1 as regulator of CXCL12-CXCR4-mediated homing and migration. J Exp Med. 2009 Aug 31;206(9):1957-70.

439    Grzmil P, Konietzko J, Boehm D, Hölter SM, Aguilar-Pimentel JA, Javaheri A, Kalaydjiev S, Adler T, Bolle I, Adham I, Dixkens C, Wolf S, Fuchs H, Gailus-Durner V, Wurst W, Ollert M, Busch DH, Schulz H, Hrabé de Angelis M, Burfeind P. Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function. Cytogenet Genome Res. 2009;125(3):186-200. DOI: 10.1159/000230003

438    Guan K, Wolf F, Becker A, Engel W, Nayernia K, Hasenfuss G. Isolation and cultivation of stem cells from adult mouse testes. Nat Protocols. 2009;4:143-54

437    Guenthner T, Jankowski V, Kretschmer A, Nierhaus M, van der Giet M, Zidek W, Jankowski J. Endothelium and vascular smooth muscle cells in the context of uremia. Semin Dial. 2009;22(4):428-432.

436    Gueorguiev M, Lecoeur C, Meyre D, Benzinou M, Mein CA, Hinney A, Vatin V,Weill J, Heude B, Hebebrand J, Grossman AB, Korbonits M, Froguel P. Associationstudies on ghrelin and ghrelin receptor gene polymorphisms with obesity. Obesity (Silver Spring). 2009 Apr;17(4):745-54. Epub 2009 Jan 22. PubMed PMID: 19165163.

435    Guipponi M, Li QX, Hyde L, Beissbarth T, Smyth GK, Masters CL, Scott HS. SAGE Analysis of Genes Differentially Expressed in Presymptomatic TgSOD1(G93A) Transgenic Mice Identified Cellular Processes Involved in Early Stage of ALS Pathology. J Mol Neurosci. 2010 May;41(1):172-82. Epub 2009 Dec 2.

434    Gunkel S, Heineke J, Hilfiker-Kleiner D, Knöll R. MLP: a stress sensor goes nuclear. J Mol Cell Cardiol. 2009 47(4):423-425.

433    Gunkel S, Linke WA, Heineke J, Hilfiker-Kleiner D, Knöll R. Response to Gehmlich et al. Letter to the Editor of the Journal of Molecular and Cellular Cardiology Regarding MLP: A Stress Sensor Goes Nuclear". J Mol Cell Cardiol. 2009.

432    Haas SC, Huber R, Gutsch R, Kandemir JD, Cappello C, Krauter J, Duyster J, Ganser A, Brand K. ITD- and FL-induced FLT3 signal transduction leads to increased C/EBPbeta-LIP expression and LIP/LAP ratio by different signalling modules. Br J Haematol. 2009 ; 148(5):777 - 790

431    Hache H, Wierling C, Lehrach H, and Herwig R.GeNGe: Systematic Generation of Gene Regulatory Networks.Bioinformatics. 2009; 25(9):1205-1207. doi 10.1093/bioinformatics/btp115

430    Hamshere ML, Schulze TG, Schumacher J, Corvin A, Owen MJ, Abou Jamra R, Propping P, Maier W, Diaz GOY, Moyoral F, Rivas F, Jones I, Jones L, Kirov G, Gill M, Holmans PA, Nothen MM, Cichon S, Rietschel M, Craddock N.  Mood-incongruent psychosis in bipolar disorder: conditional linkage analysis shows genome-wide suggestive linkage at 1q32.3, 7p13 and 20q13.31. Bipolar Disord. 2009 Sep;11(6):610-20. doi 10.1111/j.1399-5618.2009.00736.

429    Harder N, Mora-Bermúdez F, Godinez WJ, Wünsche A, Eils R, Ellenberg J, Rohr K. Automatic analysis of dividing cells in live cell movies to detect mitotic delays and correlate phenotypes in time. Genome Res, (2009), 19, 2113-24.

428    Harel L, Tcherpakov M, Costa B, Zapatka M, Oberthuer A, Hansford LM, Levy Z, Avigad S, Yaniv I, Shi L, Eils R, Fischer M, Brors B, Kaplan DR, Fainzilber M.CCM2 mediates death signalling by the TrkA receptor tyrosine kinase. Neuron. 2009 Sep 10; 63(5):585-91

427    Hartmann C, Meyer J, Balss J, Capper D, Mueller W, Christians A, Felsberg J, Wolter M, Mawrin C, Wick W, Weller M, Herold-Mende C, Unterberg A, Jeuken JWM, Wesseling P, Reifenberger G, von Deimling A; Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas. Acta Neuropathol. 2009 Jun 25. [Epub ahead of print].

426    Hartmann C, von Deimling A; Molecular Pathology of Oligodendroglial Tumors. Recent Results Cancer Res. 2009;171:25-49.

425    Hartmann M, Jackisch C, Raab G, Schneeweiss A, Possinger K, Oyee J, Harbeck N. Cost-utility analysis for advanced breast cancer therapy in Germany: results of the fulvestrant sequencing model. Breast Cancer Res Treat. 2009 Sep;117(2):305-17. Epub 2009 Jan 8.

424    Hassel D, Dahme T, Erdmann J, Meder B, Huge A, Stoll M, Just S, Hess A, Ehlermann P, Weichenhan D, Grimmler M, Liptau H, Hetzer R, Regitz-Zagrosek V, Fischer C, Nürnberg P, Schunkert H, Katus HA, Rottbauer W. Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. Nat Med. 2009 Nov;15(11):1281-8. Epub 2009 Nov 1

423    Heath JH,  SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F,Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, van der Harst P,Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott KS, Teumer A, Luan J, Lucas G, Kuusisto J, Burton PR, Hadley D, McArdle WL; Wellcome Trust CaseControl Consortium, Brown M, Dominiczak A, Newhouse SJ, Samani NJ, Webster J,Zeggini E, Beckmann JS, Bergmann S, Lim N, Song K, Vollenweider P, Waeber G,Waterworth DM, Yuan X, Groop L, Orho-Melander M, Allione A, Di Gregorio A,Guarrera S, Panico S, Ricceri F, Romanazzi V, Sacerdote C, Vineis P, Barroso I,Sandhu MS, Luben RN, Crawford GJ, Jousilahti P, Perola M, Boehnke M, Bonnycastle LL, Collins FS, Jackson AU, Mohlke KL, Stringham HM, Valle TT, Willer CJ, BergmanRN, Morken MA, Döring A, Gieger C, Illig T, Meitinger T, Org E, Pfeufer A,Wichmann HE, Kathiresan S, Marrugat J, O'Donnell CJ, Schwartz SM, Siscovick DS,Subirana I, Freimer NB, Hartikainen AL, McCarthy MI, O'Reilly PF, Peltonen L,Pouta A, de Jong PE, Snieder H, van Gilst WH, Clarke R, Goel A, Hamsten A, Peden JF, Seedorf U, Syvänen AC, Tognoni G, Lakatta EG, Sanna S, Scheet P, SchlessingerD, Scuteri A, Dörr M, Ernst F, Felix SB, Homuth G, Lorbeer R, Reffelmann T,Rettig R, Völker U, Galan P, Gut IG, Hercberg S, Lathrop GM, Zelenika D, DeloukasP, Soranzo N, Williams FM, Zhai G, Salomaa V, Laakso M, Elosua R, Forouhi NG,Völzke H, Uiterwaal CS, van der Schouw YT, Numans ME, Matullo G, Navis G,Berglund G, Bingham SA, Kooner JS, Connell JM, Bandinelli S, Ferrucci L, Watkins H, Spector TD, Tuomilehto J, Altshuler D, Strachan DP, Laan M, Meneton P, WarehamNJ, Uda M, Jarvelin MR, Mooser V, Melander O, Loos RJ, Elliott P, Abecasis GR,Caulfield M, Munroe PB. Genome-wide association study identifies eight lociassociated with blood pressure. Nat Genet. 2009 Jun;41(6):666-76. Epub 2009 May 10.

422    Heck A, Lieb R, Ellgas A, Pfister H, Lucae S, Erhardt A, Himmerich H, Horstmann S, Kloiber S, Ripke S, Müller-Myhsok B, Bettecken T, Uhr M, Holsboer F, Ising M. Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients. Am J Med Genet B Neuropsychiatr Genet. 2009 Jan 5;150B(1):104-14. PubMed PMID: 18484085.

421    Heck A, Lieb R, Ellgas A, Pfister H, Lucae S, Roeske D, Pütz B, Müller-Myhsok  B, Uhr M, Holsboer F, Ising M. Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking. Genes Brain Behav. 2009 Jun;8(4):464-72. PubMed PMID: 19566713.

420    Heck S, Rom J, Thewes V, Becker N, Blume B, Sinn HP, Deuschle U, Sohn C, Schneeweiss A, Lichter P. Estrogen-related receptor alpha expression and function is associated with the transcriptional coregulator AIB1 in breast carcinoma. Cancer Res. 2009 Jun 15;69(12):5186-93. Epub 2009 Jun 2.

419    Heid IM, Huth C, Loos RJ, Kronenberg F, Adamkova V, Anand SS, Ardlie K, Biebermann H, Bjerregaard P, Boeing H, Bouchard C, Ciullo M, Cooper JA, Corella D, Dina C, Engert JC, Fisher E, Francès F, Froguel P, Hebebrand J, Hegele RA, Hinney A, Hoehe MR, Hu FB, Hubacek JA, Humphries SE, Hunt SC, Illig T, Järvelin MR, Kaakinen M, Kollerits B, Krude H, Kumar J, Lange LA, Langer B, Li S, Luchner A, Lyon HN, Meyre D, Mohlke KL, Mooser V, Nebel A, Nguyen TT, Paulweber B, Perusse L, Qi L, Rankinen T, Rosskopf D, Schreiber S, Sengupta S, Sorice R, Suk A, Thorleifsson G, Thorsteinsdottir U, Völzke H, Vimaleswaran KS, Wareham NJ, Waterworth D, Yusuf S, Lindgren C, McCarthy MI, Lange C, Hirschhorn JN, Laird N, Wichmann HE. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: does heterogeneity of estimates relate to study design? PLoS Genet. 2009 Oct;5(10):e1000694. Epub 2009 Oct 23.

418    Heidel F, Lipka DB, Mirea FK, Mahboobi S, Grundler R, Kancha RK, Duyster J, Naumann M, Huber C, Böhmer FD, Fischer T. Bis(1H-indol-2-yl)methanones are effective inhibitors of FLT3-ITD tyrosine kinase and partially overcome resistance to PKC412A in vitro. Br J Haematol. 2009 Mar;144(6):865-74.

417    Helander A, Böttcher M, Fehr C, Dahmen N, Beck O. Detection times for urinary ethyl glucuronide and ethyl sulfate in heavy drinkers during alcohol detoxification. Alcohol Alcohol. 2009 Jan-Feb;44(1):55-61. Epub 2008 Oct 29.PubMed PMID: 18971292.

416    Helbig I, Mefford HC, Sharp AJ, Guipponi M, Fichera M, Franke A, Muhle H, de Kovel C, Baker C, von Spiczak S, Kron KL, Steinich I, Kleefuß-Lie AA, Leu C, Gaus V, Schmitz B, Kein KM, Reif PS, Rosenow F, Weber Y, Lerche H, Zimprich F, Urak L, Fuchs K, Feucht M, Genton P, Thomas P, Visscher1 F, de Haan GJ, Møller RS, Hjalgrim H, Luciano D, Wittig M, Nothnagel M, Elger CE, Nürnberg P, Romano C, Malafosse A, Koeleman BP, Lindhout D, Stephani U, Schreiber S, Eichler EE, Sander T. 15q13.3 microdeletions increase risk of idiopathic generalized epilepsy. Nat Genet. 2009 Feb;41(2):160-2. Epub 2009 Jan 11.

415    Helwig M, Archer ZA, Heldmaier G, Tups A, Mercer JG, Klingenspor M. Photoperiodic regulation of satiety mediating neuropeptides in the brainstem of the seasonal Siberian hamster (Phodopus sungorus). J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2009 Jul;195(7):631-42. doi 10.1007/s00359-009-0438-3

414    Hemminki K, Försti A, Lorenzo Bermejo J. Surveying the genomic landscape of colorectal cancer. Am J Gastroenterol 2009;104:789-90. doi 10.1038/ajg.2008.100

413    Hemminki K, Li X, Sundquist J, Sundquist K. Cancer risks in Crohn disease patients. Ann Oncol 2009;20:574-80. doi 10.1093/annonc/mdn595

412    Hempel M, Rivera Brugués N, Wagenstaller J, Lederer G, Weitensteiner A, SeidelH, Meitinger T, Strom TM. Microdeletion syndrome 16p11.2-p12.2: clinical andmolecular characterization. Am J Med Genet A. 2009 Oct;149A(10):2106-12.

411    Herder C, Lankisch M, Ziegler D, Rathmann W, Koenig W, Illig T, Döring A, Thorand B, Holle R, Giani G, Martin S, Meisinger C. Subclinical inflammation and diabetic polyneuropathy: MONICA/KORA Survey F3 (Augsburg, Germany). Diabetes Care. 2009 Apr;32(4):680-2. Epub 2009 Jan 8.

410    Herget-Rosenthal S, Glorieux G, Jankowski J, Jankowski V. Uremic toxins in acute kidney injury. Semin Dial. 2009;22(4):445-448.

409    Herold C, Steffens M, Brockschmidt FF, Baur MP, Becker T. INTERSNP: genome-wide interaction analysis guided by a priori information. Bioinformatics. 2009 Dec 15;25(24):3275-81.

408    Hippe, H.J., N.M. Wolf, I. Abu-Taha, R. Mehringer, S. Just, S. Lutz, F. Niroomand, E.H. Postel, H.A. Katus, W. Rottbauer, and T. Wieland. (2009). The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function. Proc Natl Acad Sci U S A 2009 106:16269-16274.

407    Hirrlinger J, Scheller A, Hirrlinger PG, Kellert B, Tang W, Wehr MC, Goebbels S, Reichenbach A, Sprengel R, Rossner MJ, Kirchhoff F. Split-cre complementation indicates coincident activity of different genes in vivo. PLoS One. 2009;4(1):e4286. Epub 2009 Jan 27.

406    Hoene V, Fischer M, Ivanova A, Wallach T, Berthold F, Dame C. GATA factors in human neuroblastoma: distinctive expression patterns in clinical subtypes. Br J Cancer. 2009 Oct 20;101(8):1481-9. Epub 2009 Aug 25

405    Hoffmann S, Otto C, Kurtz S, Sharma CM, Khaitovich P, Vogel J, Stadler PF, Hackermüller J. Fast mapping of short sequences with mismatches, insertions and deletions using index structures. PLoS Comput Biol. 2009 Sep;5(9):e1000502.

404    Horsch M, Recktenwald CV, Schädler S, Hrabé de Angelis M, Seliger B, Beckers J. Overexpressed vs mutated Kras in murine fibroblasts: a molecular phenotyping study. Br J Cancer. 2009 Feb 24;100(4):656-62. doi:10.1038/sj.bjc.6604882

403    Hu H, Wrogemann K, Kalscheuer V, Tzschach A, Richard H, Haas SA, Menzel C, Bienek M, Froyen G, Raynaud M, Bokhoven H, Chelly J, Ropers HH, Chen W.  Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing. HUGO J; 2009; Volume 3, Numbers 1-4 / Dezember 2009 DOI: 10.1007/s11568-010-9137-y Erratum to: Mutation screening in 86 known X-linked mental retardation genes by droplet-based multiplex PCR and massive parallel sequencing.Hu H, Wrogemann K, Kalscheuer V, Tzschach A, Richard H, Haas SA, Menzel C, Bienek M, Froyen G, Raynaud M, Van Bokhoven H, Chelly J, Ropers H, Chen W. Hugo J. 2009 Dec;3(1-4):83. Epub 2010 Apr 11.  DOI: 10.1007/s11568-010-9137

402    Hughes DA, Hinney A, Brumm H, Wermter AK, Biebermann H, Hebebrand J, Stoneking M. Increased constraints on MC4R during primate and human evolution. Hum Genet 124(6): 633-47, 2009

401    Ingason A, Rujescu D, Cichon S, Sigurdsson E, Sigmundsson T, Pietiläinen OPH, Buizer J,  Francks C, Muglia P, Gylfason A, Gustafsson O, Olason PI, Steinberg S, Hansen T, Giegling I, Möller HJ, Hartmann AM, Shianna KV, Ge D, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Picchioni M, Kiemeney LA, Franke B, Murray R, Vassos E, Ettinger U, Mühleisen TW, Tosato S, Ruggeri M, Djurovic S, Andreasson OA, GROUP, Werge T, Ophoff R, Rietschel M, Goldstein D, Noethen M, Petursson H, Stefansson K, Peltonen L, Collier DA, Stefansson H, St Clair D. (2009) Copy number variations of chromosome 16p13.1 region associated with schizophrenia. Molecular Psychiatry. 2009 Sep 29. [Epub ahead of print]. (impact factor: 2008: 12,5)

400    Isensee J, Meoli L, Zazzu V, Nabzdyk C, Witt H, Soewarto D, Effertz K, Fuchs H, Gailus-Durner V, Busch D, Adler T, Hrabé de Angelis M, Irgang M, Otto C, Ruiz-Noppinger P. Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice. Endocrinology. 2009 Apr;150(4):1722-30. doi: 10.1210/en.2008-1488

399    Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, Kohli MA, Hennings JM, Horstmann S, Kloiber S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune BT,  Arolt V, Rush AJ, Holsboer F, Müller-Myhsok B. A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression. Arch Gen Psychiatry. 2009 Sep;66(9):966-75. PubMed PMID: 19736353.

398    Itoh N, Okochi M, Tagami S, Nishitomi K, Nakayama T, Yanagida K, Fukumori A, Jiang J, Mori K, Hosono M, Kikuchi J, Nakano Y, Takinami Y, Dohi K, Nishigaki A, Takemoto H, Minagawa K, Katoh T, Willem M, Haass C, Morihara T, Tanaka T, Kudo T, Hasegawa H, Nishimura M, Sakaguchi G, Kato A, Takeda M. 1.1.Destruxin E decreases Beta-amyloid generation by reducing colocalization of beta-amyloid-cleaving enzyme 1 and beta-amyloid protein precursor. Neurodegener Dis. 2009; 6(5-6): 230-9.

397    Jankowski V, Gunthner T, Herget-Rosenthal S, Zidek W, Jankowski J. Dinucleoside polyphosphates and uremia. Semin Dial. 2009;22(4):396-399.

396    Jankowski V, van der Giet M, Mischak H, Morgan M, Zidek W, Jankowski J. Dinucleoside polyphosphates: strong endogenous agonists of the purinergic system. Br J Pharmacol. 2009;157(7):1142-1153.

395    Jendrach M, Gispert S, Ricciardi F, Klinkenberg M, Schemm R, Auburger G.The mitochondrial kinase PINK1, stress response and Parkinsons disease. J Bioenerg Biomembr. 2009 Dec;41(6):481-6.

394    Jones AR, Lister AL, Hermida L, Wilkinson P, Eisenacher M, Belhajjame K, Gibson F, Lord P, Pocock M, Rosenfelder H, Santoyo-Lopez J, Wipat A, Paton NW (2009) Modeling and managing experimental data using FuGE. OMICS 2009 13: 239-251.

393    Kahle PJ, Waak J, Gasser T. DJ-1 and prevention of oxidative stress in Parkinson's disease and other age-related disorders. Free Radic Biol Med. 2009 Nov 15;47(10):1354-61.

392    Karpinar DP, Balija MB, Kügler S, Opazo F, Rezaei-Ghaleh N, Wender N, Kim HY, Taschenberger G, Falkenburger BH, Heise H, Kumar A, Riedel D, Fichtner L, Voigt A, Braus GH, Giller K, Becker S, Herzig A, Baldus M, Jäckle H, Eimer S, Schulz JB, Griesinger C, Zweckstetter M.Pre-fibrillar alpha-synuclein variants with impaired beta-structure increase neurotoxicity in Parkinson's disease models.EMBO J. 2009 Oct 21;28(20):3256-68. doi:10.1038/emboj.2009.257 PMID: 19745811

391    Kawamata N, Ogawa S, Seeger K, Kirschner-Schwabe R, Huynh T, Chen J, Megrabian N, Harbott J, Zimmermann M, Martin Schrappe M, Bartram CR, Koeffler HP. Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia. Int J Oncol. 2009 Jun; 34(6):1603-1612. doi 10.3892/ijo_00000290

390    Kegel KB, Schewkunow V, Sapp E, Masso N, Wanker EE, DiFiglia M, Goldmann WH. Polyglutamine expansion in huntingtin increases its insertion into lipid bilayers. Biochemical and Biophysical Research Communications. 2009 Sep;  387 (3):472-475. doi 10.1016/j.bbrc.2009.07.039

389    Kemter E, Rathkolb B, Rozman J, Hans W, Schrewe A, Landbrecht C, Klaften M, Ivandic B, Fuchs H, Gailus-Durner V, Klingenspor M, Hrabé de Angelis M, Wolf E, Wanke R, Aigner B. Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism. Am J Physiol Renal Physiol. 2009 Nov;297(5):F1391-8. doi:10.1152/ajprenal.00261.2009

388    Ketterer, K., Kong, B., Frank, D., Giese, N., Bauer, A., Hoheisel, J.D., Korc, M., Kleeff, J., Michalski, C. & Friess, H. (2009). Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathway. Cancer Lett. 277, 72-81.

387    Khasawneh J, Schulz MD, Walch A, Rozman J, Hrabe de Angelis M, Klingenspor M, Buck A, Schwaiger M, Saur D, Schmid RM, Klöppel G, Sipos B, Greten FR, Arkan MC. Inflammation and mitochondrial fatty acid ?-oxidation link obesity to early tumor promotion. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3354-9. doi: 10.1073/pnas.0802864106

386    Kim HY, Cho MK, Kumar A, Maier E, Siebenhaar C, Becker S, Fernandez CO, Lashuel HA, Benz R, Lange A, Zweckstetter M. Structural properties of pore-forming oligomers of alpha-synuclein. J Am Chem Soc. 2009 Dec 2;131(47):17482-9.

385    Kirov G, Zaharieva I, Georgieva L, Moskvina V, Nikolov I, Cichon S, Hillmer A, Toncheva D, Owen MJ, O´Donovan MC.  A genome-wide association study in 574 schizophrenia trios using DNA pooling. Mol Psychiatry. 2009 Aug;14(8):796-803. doi:10.1038/mp.2008.33

384    Kleefuss-Lie A, Friedl W, Cichon S, Haug K, Warnstedt M, Alekov A, Sander T, Ramirez A, Poser B, Maljevic S, Hebeisen S, Kubisch C, Rebstock J, Horvath S, Hallmann K, Dullinger JS, Rau B, Haverkamp F, Beyenburg S, Schulz H, Janz D, Giese B, Müller-Newen G, Propping P, Elger CE, Fahlke C, Lerche H. CLCN2 variants in idiopathic generalized epilepsy. Nat Genet. 2009 Sep;41(9):954-5. PMID: 19710712

383    Kloiber S, Kohli MA, Brueckl T, Ripke S, Ising M, Uhr M, Menke A, Unschuld PG, Horstmann S, Salyakina D, Muller-Myhsok B, Binder EB, Holsboer F, Lucae S. Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Mol Psychiatry. 2010 Jul;15(7):736-47. Epub 2009 Jan 6.

382    Klonisch T, Glogowska A, Gratao AA, Grzech M, Nistor A, Torchia M, Weber E, Hrabé de Angelis M, Rathkolb B, Cuong HV, Wolf E, Schneider MR. The C-terminal cytoplasmic domain of human proEGF is a negative modulator of body and organ weights in transgenic mice. FEBS Lett. 2009 Apr 17;583(8):1349-57. doi:10.1016/j.febslet.2009.03.051

381    Klöting N, Berthold S, Kovacs P, Schön MR, Fasshauer M, Ruschke K, Stumvoll M, Blüher M. MicroRNA expression in human omental and subcutaneous adipose tissue. PLoS One. 2009;4(3):e4699.

380    Knöll R. Dilatative Kardiomyopathie - eine aktuelle Bestandsaufnahme. Med Report. 2009(9):2.
379    Knöll R. Molekulargenetische Grundlagen der dilatativen Kardiomyopathie. Der Kardiologe. 2009:3:443-452

378    Koch A, Lehmann-Horn K, Dächsel JC, Gasser T, Kahle PJ, Lücking CB. Proteasomal inhibition reduces parkin mRNA in PC12 and SH-SY5Y cells. Parkinsonism Relat Disord. 2009 Mar;15(3):220-5.

377    Kocks J.R., H. Adler, H. Danzer, K. Hoffmann, D. Jonigk, U. Lehmann and Förster R.: Chemokine receptor CCR7 contributes to a rapid and efficient clearance of lytic MHV-68 from the lung while bronchus-associated lymphoid tissue harbours virus during latency. J. of Immunology 182 (2009): 6861-6869

376    Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt DR, Aulchenko Y, Beckmann JS, Bergmann S, Bochud M, Brown M, Campbell H; EUROSPAN Consortium, Connell J, Dominiczak A, Homuth G, Lamina C, McCarthy MI; ENGAGE Consortium, Meitinger T, Mooser V, Munroe P, Nauck M, Peden J, Prokisch H, Salo P, Salomaa V, Samani NJ, Schlessinger D, Uda M, Völker U, Waeber G, Waterworth D, Wang-Sattler R, Wright AF, Adamski J, Whitfield JB, Gyllensten U, Wilson JF, Rudan I, Pramstaller P, Watkins H; PROCARDIS Consortium, Doering A, Wichmann HE; KORA Study, Spector TD, Peltonen L, Völzke H, Nagaraja R, Vollenweider P, Caulfield M; WTCCC, Illig T, Gieger C. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet. 2009 Jun;5(6):e1000504. Epub 2009 Jun 5.

375    Kong A, Steinthorsdottir V, Masson G, Thorleifsson G, Sulem P, Besenbacher S, Jonasdottir A, Sigurdsson A, Kristinsson KT, Jonasdottir A, Frigge ML, Gylfason A, Olason PI, Gudjonsson SA, Sverrisson S, Stacey SN, Sigurgeirsson B, Benediktsdottir KR, Sigurdsson H, Jonsson T, Benediktsson R, Olafsson JH, Johannsson OT, Hreidarsson AB, Sigurdsson G; DIAGRAM Consortium, Ferguson-Smith AC, Gudbjartsson DF, Thorsteinsdottir U, Stefansson K. Parental origin of sequence variants associated with complex diseases. Nature. 2009 Dec 17;462(7275):868-74.

374    Korf U, Lobke C, Sahin O, Haller F, Sultmann H, Arlt D, Poustka A. Reverse-phase protein arrays for application-orientated cancer research. Proteomics Clinical Applications. 2009. 3(10):1140-1150. DOI: 10.1002/prca.200780035

373    Korshunov A, Meyer J, Capper D, Christians A, Remke M, Witt H, Pfister S, von Deimling A, Hartmann C; Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma. Acta Acta Neuropathol. 2009 Jun 19. [Epub ahead of print].

372    Kruger R, Sharma M, Riess O, Gasser T, Van Broeckhoven C, Theuns J, Aasly J, Annesi G, Bentivoglio AR, Brice A, Djarmati A, Elbaz A, Farrer M, Ferrarese C, Gibson JM, Hadjigeorgiou GM, Hattori N, Ioannidis JP, Jasinska-Myga B, Klein C, Lambert JC, Lesage S, Lin JJ, Lynch T, Mellick GD, de Nigris F, Opala G, Prigione A, Quattrone A, Ross OA, Satake W, Silburn PA, Tan EK, Toda T, Tomiyama H, Wirdefeldt K, Wszolek Z, Xiromerisiou G, Maraganore DM, for the Genetic Epidemiology of Parkinson's disease c. A large-scale genetic association study to evaluate the contribution of Omi/HtrA2 (PARK13) to Parkinson's disease. Neurobiol Aging. 2009 Dec 23.

371    Kuhn C, Frank D, Will R, Jaschinski C, Frauen R, Katus HA, Frey N. DYRK1A is a novel negative regulator of cardiomyocyte hypertrophy. (2009) J Biol Chem 284(25): 17320-17327.

370    Kuhner S, van Noort V, Betts MJ, Leo-Macias A, Batisse C, Rode M, Yamada T, Maier T, Bader S, Beltran-Alvarez P, Castano-Diez D, Chen WH, Devos D, Guell M, Norambuena T, Racke I, Rybin V, Schmidt A, Yus E, Aebersold R, Herrmann R, Bottcher B, Frangakis AS, Russell RB, Serrano L, Bork P, Gavin AC (2009) Proteome organization in a genome-reduced bacterium. Science 2009 326: 1235-1240.

369    Kurzwelly D, Glas M, Roth P, Weimann E, Lohner H, Waha A, Schabet M, Reifenberger G, Weller M, Herrlinger U. Primary CNS lymphoma in the elderly: temozolomide therapy and MGMT status. J Neurooncol. 2009 Oct 20.

368    LaFramboise T, Winckler W, Thomas RK. A flexible rank-based framework for detecting copy number aberrations from array data. Bioinformatics.  2009 Mar 15;25(6):722-8

367    Laumen H, Saningong AD, Heid IM, Hess J, Herder C, Claussnitzer M, Baumert J, Lamina C, Rathmann W, Sedlmeier EM, Klopp N, Thorand B, Wichmann HE, Illig T, Hauner H. Functional characterization of promoter variants of the adiponectin gene complemented by epidemiological data. Diabetes. 2009 Apr;58(4):984-91. Epub 2008 Dec 15.

366    Laws SM, Eckart K, Friedrich P, Eisele T, Kurz A, Förstl H, Riemenschneider M. No association of lipase C polymorphisms with Alzheimer´s disease. Neurobiol Aging. 2009. [Epub ahead of print]

365    Laws SM, Eckart K, Friedrich P, Kurz A, Förstl H, Riemenschneider M. Lack of evidence to support the association of polymorphisms within the alpha- and beta-secretase genes (ADAM10/BACE1) with Alzheimer´s disease. Neurobiol Aging. 2009 [Epub ahead of print]

364    Lehmann LH, Schaeufele T, Buss SJ, Balanova M, Hartschuh W, Ehlermann P, Katus IMAGE CARDIO MED. A patient with LEOPARD syndrome and PTPN11 mutation. Circulation. 2009 Mar 10;119(9):1328-9

363    Lewis MA, Quint E, Glazier AM, Fuchs H, Hrabé de Angelis M, Langford C, van Dongen S, Abreu-Goodger C, Piipari M, Redshaw N, Dalmay T, Moreno-Pelayo MA, Enright AJ, Steel KP. An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet. 2009 May;41(5):614-8. doi:10.1038/ng.369

362    Lin YH, Kakadia PM, Chen Y, Li YQ, Deshpande AJ, Buske C, Zhang KL, Zhang Y, Xu GL, Bohlander SK. Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias. Blood. 2009 Jul 16;114(3):651-8. Epub 2009 May 14.

361    Lin Z, Poritz L, Franke A, Li TY, Ruether A, Byrnes KA, Wang Y, Gebhard AW, MacNeill C, Thomas NJ, Wu R, Schreiber S, Koltun WA. Genetic association of DLG5 R30Q with familial and sporadic inflammatory bowel disease in men. Dis Markers. 2009;27(5):193-201.

360    Lindgren CM, Heid IM, Randall JC, Lamina C, Steinthorsdottir V, Qi L, Speliotes EK, Thorleifsson G, Willer CJ, Herrera BM, Jackson AU, Lim N, Scheet P, Soranzo N, Amin N, Aulchenko YS, Chambers JC, Drong A, Luan J, Lyon HN, Rivadeneira F, Sanna S, Timpson NJ, Zillikens MC, Zhao JH, Almgren P, Bandinelli S, Bennett AJ, Bergman RN, Bonnycastle LL, Bumpstead SJ, Chanock SJ, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Doney AS, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Forouhi NG, Gieger C, Grallert H, Groves CJ, Grundy S, Guiducci C, Hadley D, Hamsten A, Havulinna AS, Hofman A, Holle R, Holloway JW, Illig T, Isomaa B, Jacobs LC, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Lathrop GM, Lawlor DA, Mangino M, McArdle WL, Meitinger T, Morken MA, Morris AP, Munroe P, Narisu N, Nordström A, Nordström P, Oostra BA, Palmer CN, Payne F, Peden JF, Prokopenko I, Renström F, Ruokonen A, Salomaa V, Sandhu MS, Scott LJ, Scuteri A, Silander K, Song K, Yuan X, Stringham HM, Swift AJ, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Walters GB, Weedon MN; Wellcome Trust Case Control Consortium, Witteman JC, Zhang C, Zhang W, Caulfield MJ, Collins FS, Davey Smith G, Day IN, Franks PW, Hattersley AT, Hu FB, Jarvelin MR, Kong A, Kooner JS, Laakso M, Lakatta E, Mooser V, Morris AD, Peltonen L, Samani NJ, Spector TD, Strachan DP, Tanaka T, Tuomilehto J, Uitterlinden AG, van Duijn CM, Wareham NJ, Hugh Watkins; Procardis Consortia, Waterworth DM, Boehnke M, Deloukas P, Groop L, Hunter DJ, Thorsteinsdottir U, Schlessinger D, Wichmann HE, Frayling TM, Abecasis GR, Hirschhorn JN, Loos RJ, Stefansson K, Mohlke KL, Barroso I, McCarthy MI; Giant Consortium. Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet. 2009 Jun;5(6):e1000508. Epub 2009 Jun 26. Erratum in: PLoS Genet. 2009 Jul;5(7). doi: 10.1371/annotation/b6e8f9f6-2496-4a40-b0e3-e1d1390c1928.

359    Ling KH, Hewitt CA, Beissbarth T, Hyde L, Banerjee K, Cheah PS, Cannon PZ, Hahn CN, Thomas PQ, Smyth GK, Tan SS, Thomas S, Scott HS. Transcriptome profiling of the developing mouse cerebral cortex reveals spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts. Genom Biol, 2009, 10(10):R104.

358    Lipinski S, Till A, Sina C, Arlt A, Grasberger H, Schreiber S, Rosenstiel P. DUOX2-derived reactive oxygen species are effectors of NOD2-mediated antibacterial responses. J Cell Sci. 2009 Oct 1;122(Pt 19):3522-30.

357    Liu S, Breit S, Danckwardt S, Muckenthaler MU, Kulozik AE:Downregulation of Notch signalling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines. Ann Hematol 88: 613 - 621, 2009 Epub 2008 Dec 5.

356    Loos BG, Fiebig A, Nothnagel M, Jepsen S, Groessner-Schreiber B, Franke A, Jervøe-Storm PM, Schenck K, van der Velden U, Schreiber S. NOD1 gene polymorphisms in relation to aggressive periodontitis. Innate Immun. 2009 Aug;15(4):225-32

355    Lourenço FC, GalvanV, Fombonne J, Corset V, Llambi F, Müller U, Bredesen DE, Mehlen P (2009) Netrin-1 interacts with amyloid precursor protein and regulates amyloid-production. Cell Death Diff 2009; 16:655-663

354    Lu TT, Lao O, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Nielsen F, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Ruether A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Kayser M, Krawczak M. An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population. Eur J Hum Genet. 2009 Jul;17(7):967-75

353    Ludwig KU, Mattheisen M, Mühleisen TW, Roeske D, Schmäl C, Breuer R, Schulte-Körne G, Müller-Myhsok B, Nöthen MM, Hoffmann P, Rietschel M, Supporting evidence for LRRTM1 imprinting effects in schizophrenia. Cichon S. Mol Psychiatry. 2009 Aug;14(8):743-5.

352    Luedde M, Flögel U, Knorr M, Grundt C, Hippe HJ, Brors B, Frank D, HaselmannU, Antony C, Voelkers M, Schrader J, Most P, Lemmer B, Katus HA, Frey N.Decreased contractility due to energy deprivation in a transgenic rat model ofhypertrophic cardiomyopathy. J Mol Med. 2009 Apr;87(4):411-22.

351    Lueth M, Wronski L, Giese A, Kirschner-Schwabe R, Pietsch T, von Deimling A, Henze G, Kurtz A, Driever PH. Somatic mitochondrial mutations in pilocytic astrocytoma. Cancer Genet Cytogenet. 2009 Jul; 192(1):30-35.

350    Lugnier C, Majores M, Fassunke J, Pernhorst K, Niehusmann P, Simon M,Nellist M, Schoch S, Becker A. Hamartin variants frequent in focaldysplasias and cortical tubers reveal reduced tuberin binding and aberrantsubcellular distribution in vitro. J Neuropathol Exp Neurol,68(10):1136-1146, 2009.

349    Lutz AK, Exner N, Fett ME, Schlehe JS, Kloos K, Lämmermann K, Brunner B, Kurz-Drexler A, Vogel F, Reichert AS, Bouman L, Vogt-Weisenhorn D, Wurst W, Tatzelt J, Haass C, Winklhofer KF.Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation. J Biol Chem. 2009 Aug 21;284(34):22938-51. Epub 2009 Jun 22.

348    Madzar D, Schulte C, Gasser T. Screening for LRRK2 R1441 mutations in a cohort of PSP patients from Germany. Eur J Neurol. 2009 Nov;16(11):1230-2.

347    Mahachie JJM, Baurecht H, Rodríguez E, Naumann A, Wagenpfeil S, Klopp N, Mempel M, Novak N, Bieber T, Wichmann HE, Ring J, Illig T, Cattaert T, Van Steen K, Weidinger S. Analysis of the high affinity IgE receptor genes reveals epistatic effects of FCER1A variants on eczema risk. Allergy. 2009 Dec 21.

346    Mallm, J.-P., Jakob-Andreas Tschäpe, J. A., Hick, M., Filippov, M. A. and C. Müller, U. C. (2009). Generation of conditional null alleles for APP and APLP2. Genesis 48: 200. (DOI: 10.1002/dvg.20601)

345    Malzkorn B, Wolter M, Liesenberg F, Grzendowski M, Stühler K, Meyer HE, Reifenberger G. Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas. Brain Pathol. 2009 Aug 19. [Epub ahead of print]

344    Mameli M, Halbout B, Creton C, Spanagel R, Lüscher C Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the nucleus accumbens. Nat Neurosci 12 (2009), 1036-1041

343    Manickam R, Kuryshev VY, Lanzer M, Brosius J, Tang TH, Rozhdestvensky TS (2010) A global view of the nonprotein-coding transcriptome in Plasmodium falciparum. Nucleic Acids Res 38:608-617. Epub 2009 Oct 28.

342    Marenholz I, Kerscher T, Bauerfeind A, Esparza-Gordillo J, Nickel R, Keil T, Lau S, Rohde K, Wahn U, Lee YA. An interaction between filaggrin mutations and early food sensitization improves the prediction of childhood asthma. J Allergy Clin Immunol 123, 911-916. 2009.

341    Marenholz I, Lee YA. Die Genetik des atopischen Ekzems ? Neue Gene und Pathomechanismen. Med Genetik 21, 493-497. 2009.

340    Markoullis K, Bulian D, Hölzlwimmer G, Quintanilla-Martinez L, Heiliger KJ, Zitzelsberger H, Scherb H, Mysliwietz J, Uphoff CC, Drexler HG, Adler T, Busch DH, Schmidt J, Mahabir E. Mycoplasma contamination of murine embryonic stem cells affects cell parameters, germline transmission and chimeric progeny.Transgenic research 2009 Feb; 18(1):71-87. PMID: 18819014

339    Matthäus F., Smith V.A., Fogtman A., Sommer W.H., Leonardi-Essmann F., Lourdusamy A., Reimers M.A., Spanagel R., Gebicke-Haerter P.J., Interactive molecular networks obtained by computer-aided conversion of microarray data from brains of alcohol-drinking rats. Pharmacopsychiatry. 2009; 42(Suppl. 1): S118-S128.

338    McCarthy SE, Makarov V, Kirov G, Addington AM, McClellan J, Yoon S, Perkins DO, Dickel DE, Kusenda M, Krastoshevsky O, Krause V, Kumar RA, Grozeva D, Malhotra D, Walsh T, Zackai EH, Kaplan P, Ganesh J, Krantz ID, Spinner NB, Roccanova P, Bhandari A, Pavon K, Lakshmi B, Leotta A, Kendall J, Lee YH, Vacic V, Gary S, Iakoucheva LM, Crow TJ, Christian SL, Lieberman JA, Stroup TS, Lehtimäki T, Puura K, Haldeman-Englert C, Pearl J, Goodell M, Willour VL, Derosse P, Steele J, Kassem L, Wolff J, Chitkara N, McMahon FJ, Malhotra AK, Potash JB, Schulze TG, Nöthen MM, Cichon S, Rietschel M, Leibenluft E, Kustanovich V, Lajonchere CM, Sutcliffe JS, Skuse D, Gill M, Gallagher L, Mendell NR; Wellcome Trust Case Control Consortium, Craddock N, Owen MJ, O'Donovan MC, Shaikh TH, Susser E, Delisi LE, Sullivan PF, Deutsch CK, Rapoport J, Levy DL, King MC, Sebat J. Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet. 2009 Nov;41(11):1223-7. doi:10.1038/ng.474

337    Meder B, Katus HA, Rottbauer W. Genetik der hypertrophischen Kardiomyopathie. Journal für Kardiologie 2009

336    Meder B, Katus HA, Rottbauer W. Leichte Kette mit schweren Folgen - Der Zebrafish als Modell genetischer Herzschwäche. GenomXpress 2009; 3.09

335    Meder, B., C. Laufer, D. Hassel, S. Just, S. Marquart, B. Vogel, A. Hess, M.C. Fishman, H.A. Katus, and W. Rottbauer. (2009). A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivo. Circ Res 104:650-659

334    Meisinger C, Prokisch H, Gieger C, Soranzo N, Mehta D, Rosskopf D, LichtnerP, Klopp N, Stephens J, Watkins NA, Deloukas P, Greinacher A, Koenig W, Nauck M, Rimmbach C, Völzke H, Peters A, Illig T, Ouwehand WH, Meitinger T, Wichmann HE,Döring A. A genome-wide association study identifies three loci associated withmean platelet volume. Am J Hum Genet. 2009 Jan;84(1):66-71.

333    Melum E, Franke A, Karlsen TH. Genome-wide association studies--a summary for the clinical gastroenterologist. World J Gastroenterol. 2009 Nov 21;15(43):5377-96.

332    Mestdagh, P., P. Van Vlierberghe, A. De Weer, D. Muth, F. Westermann, F. Speleman, and J. Vandesompele, A novel and universal method for microRNA RT-qPCR data normalization. Genome Biol, 2009. 10(6): p. R64, IF 6.589.

331    Metzeler KH, Dufour A, Benthaus T, Hummel M, Sauerland MC, Heinecke A, Berdel WE, Büchner T, Wörmann B, Mansmann U, Braess J, Spiekermann K, Hiddemann W, Buske C, Bohlander SK. ERG expression is an independent prognostic factor and allows refined risk stratification in cytogenetically normal acute myeloid leukemia: a comprehensive analysis of ERG, MN1, and BAALC transcript levels using oligonucleotide microarrays. J Clin Oncol. 2009 Oct 20;27(30):5031-8. Epub 2009 Sep 14.

330    Meyer CW, Wagener A, Rink N, Hantschel C, Heldmaier G, Klingenspor M, Brockmann BA. High energy digestion efficiency and altered lipid metabolism contribute to obesity in BFMI mice. Obesity (2009) 17 11, 1988–1993. doi:10.1038/oby.2009.124

329    Meyer J, Pusch S, Balss J, Capper C, Mueller W, Christians A, Hartmann C,  von Deimling A; PCR and Restriction Endonuclease based Detection of IDH1 Mutations. Brain Pathology, Brain Pathol. 2009 Aug 18.

328    Mier D, Kirsch P, Meyer-Lindenberg A. Neural substrates of pleiotropic action of genetic variation in COMT: a meta-analysis. Mol Psychiatry. 2009 May 5. [Epub ahead of print]

327    Mittelstaedt T, Seifert G, Alvarez-Barón E, Steinhäuser C, Becker AJ, SchochS. Differential mRNA expression patterns of the synaptotagmin gene family inthe rodent brain. J Comp Neurol, 512(4):514-528, 2009.

326    Möckelmann N, von Schönfels W, Buch S, von Kampen O, Sipos B, Egberts JH, Rosenstiel P, Franke A, Brosch M, Hinz S, Röder C, Kalthoff H, Fölsch UR, Krawczak M, Schreiber S, Bröring CD, Tepel J, Schafmayer C, Hampe J. Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer. BMC Gastroenterol. 2009 20;9:79.

325    Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, and De Strooper B.Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. EMBO Mol Med. 2009 May;1(2):99-111.

324    Muller S, Marenholz I, Lee YA, Sengler C, Zitnik SE, Griffioen RW, Meglio P, Wahn U, Nickel R. Association of Filaggrin loss-of-function-mutations with atopic dermatitis and asthma in the Early Treatment of the Atopic Child (ETAC) population. Pediatr Allergy Immunol 20, 358-361. 2009.

323    Nagane M, Nozue K, Shimizu S, Waha A, Miyazaki H, Kurita H, Homori M, Fujioka Y, Shiokawa Y. Prolonged and severe thrombocytopenia with pancytopenia induced by radiation-combined temozolomide therapy in a patient with newly diagnosed glioblastoma--analysis of O6-methylguanine-DNA methyltransferase status.  J Neurooncol. 2009 Apr;92(2):227-32. Epub 2008 Nov 27.

322    Nair RP, Duffin KC, Helms C, Ding J, Stuart PE, Goldgar D, Gudjonsson JE, Li Y, Tejasvi T, Feng BJ, Ruether A, Schreiber S, Weichenthal M, Gladman D, Rahman P, Schrodi SJ, Prahalad S, Guthery SL, Fischer J, Liao W, Kwok PY, Menter A, Lathrop GM, Wise CA, Begovich AB, Voorhees JJ, Elder JT, Krueger GG, Bowcock AM, Abecasis GR.  Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet 2009; 41(2):199-204. doi:10.1038/ng.311 PMCID: PMC2745122

321    Nord H, Hartmann C, Andersson R, Menzel U, Pfeifer S, Piotrowski A, Bogdan A, Läkare A, Olofsson O, Hesselager G, Blomquist E, Komorowski J, von Deimling A, Bruder CEG, Dumanski JP, de Stahl TD; Multiple and complex aberrations characterize the genome of glioblastoma tumors - Novel loci identified using a human 32K BAC array. Neuro Oncol. 2009 Dec; 11(6): 803-18

320    Nothnagel M, Ellinghaus D, Schreiber S, Krawczak M, Franke A. Acomprehensive evaluation of SNP genotype imputation. Hum Genet. 2009Mar;125(2):163-71. Epub 2008 Dec 17.

319    Noyes HA, Alimohammadian MH, Agaba M, Brass A, Fuchs H, Gailus-Durner V, Hulme H, Iraqi F, Kemp S, Rathkolb B, Wolf E, Hrabé de Angelis M, Roshandel D, Naessens J. Mechanisms controlling anaemia in Trypanosoma congolense infected mice. PLoS One. 2009;4(4):e5170. doi:10.1371/journal.pone.0005170

318    Oberthuer A, Theissen J, Westermann F, Hero B, Fischer M.Molecular characterization and classification of neuroblastoma. Future Oncol, 2009, 5(5): 625-639.

317    O'Donovan MC, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, Leung HT, Giegling I, Hartmann AM, Möller HJ, Morris DW, Shi Y, Feng G, Hoffmann P, Propping P, Vasilescu C, Maier W, Rietschel M, Zammit S, Schumacher J, Quinn EM, Schulze TG, Iwata N, Ikeda M, Darvasi A, Shifman S, He L, Duan J, Sanders AR, Levinson DF, Adolfsson R, Osby U, Terenius L, Jönsson EG, Cichon S, Nöthen MM, Gill M, Corvin AP, Rujescu D, Gejman PV, Kirov G, Craddock N, Williams NM, Owen MJ; Molecular Genetics of Schizophrenia Collaboration. Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroplast growth factor receptor 2.  Mol Psychiatry. 2009 Jan;14(1):30-6. doi:10.1038/mp.2008.108

316    Oehme I, Deubzer HE, Lodrini M, Milde T, Witt O.Targeting of HDAC8 and investigational inhibitors in neuroblastoma. Expert Opin Investig Drugs. 2009 Nov; 18(11):1605-17.

315    Oehme I, Deubzer HE, Wegener D, Pickert D, Linke JP, Hero B, Kopp-Schneider A, Westermann F, Ulrich S, Fischer M, Witt O.Histone deacetylase 8 in neuroblastoma tumorigenesis. Clin Cancer Res, 2009, 15(1): 91-99.

314    Otte DM, Bilkei-Gorzó A, Filiou MD, Turck CW, Yilmaz Ö, Holst MI, Schilling K, Abou-Jamra R, Schumacher J, Benzel I, Kunz WS, Beck H, Zimmer A.:Behavioral changes in G72/G30 transgenic mice. European Neuropsychopharmacology - May 2009 Vol. 19, Issue 5, Pages 339-348, DOI: 10.1016/j.euroneuro.2008.12.009

313    Palidwor GA, Shcherbinin S, Huska MR, Rasko T, Stelzl U, Arumughan A, Foulle R, Porras P, Sanchez-Pulido L, Wanker EE, Andrade-Navarro MA. Detection of alpha-rod protein repeats using a neural network and application to huntingtin. PLoS Comput Biol. 2009 5: e1000304. doi 110.1371/journal.pcbi.1000304

312   Palumbo V, Segat L, Padovan L, Amoroso A, Trimarco B, Izzo R, Lembo G, Zagrosek VR, Knöll R, Brancaccio M, Tarone G, Crovella S. Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients. BMC Med Genet. 2009;10:140.

311   Papenfort K, Said N, Welsink T, Lucchini S, Hinton JC, Vogel J.  Specific and pleiotropic patterns of mRNA regulation by ArcZ, a conserved, Hfq-dependent small RNA. Mol Microbiol. 2009 Oct;74(1):139-58.

310   Paquet D, Bhat R, Sydow A, Mandelkow EM, Berg S, Hellberg S, Fälting J, Distel M, Köster RW, Schmid B, Haass C. A zebrafish model of tauopathy allows in vivo imaging of neuronal cell de


309  Parlato R, Otto C, Tuckerman J, Stotz S, Kaden S, Gröne H-J, Unsicker K, Schütz G. Conditional inactivation of the glucocorticoid receptor gene in dopamin-?-hydroxylase cells impairs chromaffin cell survival. Endocrinology. 2009; 150:1775-1718. (2008 Nov 26 Epub ahead of print).

308  Pechlivanis S, Lorenzo Bermejo J, Pardini B, Naccarati A, Vodickova L, Novotny J, Hemminki K, Vodicka P, Försti A. Genetic variation in adipokine genes and risk of colorectal cancer. Eur J Endocrinol 2009 Jun;160(6):933-40. doi 10.1530/EJE-09-0039

307  Perreau-Lenz S, Zghoul T, Rodriguez de Fonseca F, Spanagel R, Bilbao A (2009) Circadian regulation of ethanol sensitivity by the mPer2 gene. Addict Biol 14, 253-9

306  Perry JR, Weedon MN, Langenberg C, Jackson AU, Lyssenko V, Sparsø T, Thorleifsson G, Grallert H, Ferrucci L, Maggio M, Paolisso G, Walker M, Palmer CN, Payne F, Young E, Herder C, Narisu N, Morken MA, Bonnycastle LL, Owen KR, Shields B, Knight B, Bennett A, Groves CJ, Ruokonen A, Jarvelin MR, Pearson E, Pascoe L, Ferrannini E, Bornstein SR, Stringham HM, Scott LJ, Kuusisto J, Nilsson P, Neptin M, Gjesing AP, Pisinger C, Lauritzen T, Sandbaek A, Sampson M, Zeggini ME, Lindgren CM, Steinthorsdottir V, Thorsteinsdottir U, Hansen T, Schwarz P, Illig T, Laakso M, Stefansson K, Morris AD, Groop L, Pedersen O, Boehnke M, Barroso I, Wareham NJ, Hattersley AT, McCarthy MI, Frayling TM. Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet. 2010 Feb 1;19(3):535-44. Epub 2009 Nov 18.

305  Peters DD, Lepikhov K, Rodenacker K, Marschall S, Boersma A, Hutzler P, Scherb H, Walter J, Hrabé de Angelis M. Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes. Mamm Genome. 2009 Sep-Oct;20(9-10):664-73. DOI 10.1007/s00335-009-9227-0

304  Pfeiffer V, Papenfort K, Lucchini S, Hinton JC, Vogel J. Coding sequence targeting by MicC RNA reveals bacterial mRNA silencing downstream of translational initiation. Nat Struct Mol Biol. 2009 Aug;16(8):840-6.

303  Pfeufer A, Sanna S, Arking DE, Müller M, Gateva V, Fuchsberger C, Ehret GB, Orrú M, Pattaro C, Köttgen A, Perz S, Usala G, Barbalic M, Li M, Pütz B, Scuteri A, Prineas RJ, Sinner MF, Gieger C, Najjar SS, Kao WH, Mühleisen TW, Dei M, Happle C, Möhlenkamp S, Crisponi L, Erbel R, Jöckel KH, NaitzaS, Steinbeck G, Marroni F, Hicks AA, Lakatta E, Müller-Myhsok B, Pramstaller PP, Wichmann HE, Schlessinger D, Boerwinkle E, Meitinger T, Uda M, Coresh J, Kääb S, Abecasis GR, Chakravarti A. Common variants at ten loci modulate the QT interval duration in the QTSCD Study Nat Genet. 2009Apr;41(4):407-14. Epub 2009 Mar 22

302  Pfister S, Hartmann C, Korshunov A; Histology and molecular pathology of pediatric brain tumors. J Child Neurol. 2009 Nov;24(11):1375-86

301  Pham TT, Giesert F, Röthig A, Floss T, Kallnik M, Weindl K, Hölter SM, Ahting U, Prokisch H, Becker L, Klopstock T, Hrabé de Angelis M, Beyer K, Görner K, Kahle PJ, Vogt Weisenhorn DM, Wurst W. DJ-1-deficient mice show less TH-positive neurons in the ventral tegmental area and exhibit non-motoric behavioural impairments. Genes Brain Behav. 2010 Apr;9(3):305-17. doi: 10.1111/j.1601-183X.2009.00559.x


300    Prinzen C, Trümbach D, Wurst W, Endres K, Postina R, Fahrenholz F. Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice. BMC Genomics. 2009 Feb 5;10:66.

299    Prokopenko I, Langenberg C, Florez JC, Saxena R, Soranzo N, Thorleifsson G, Loos RJ, Manning AK, Jackson AU, Aulchenko Y, Potter SC, Erdos MR, Sanna S, Hottenga JJ, Wheeler E, Kaakinen M, Lyssenko V, Chen WM, Ahmadi K, Beckmann JS, Bergman RN, Bochud M, Bonnycastle LL, Buchanan TA, Cao A, Cervino A, Coin L, Collins FS, Crisponi L, de Geus EJ, Dehghan A, Deloukas P, Doney AS, Elliott P, Freimer N, Gateva V, Herder C, Hofman A, Hughes TE, Hunt S, Illig T, Inouye M, Isomaa B, Johnson T, Kong A, Krestyaninova M, Kuusisto J, Laakso M, Lim N, Lindblad U, Lindgren CM, McCann OT, Mohlke KL, Morris AD, Naitza S, Orrù M, Palmer CN, Pouta A, Randall J, Rathmann W, Saramies J, Scheet P, Scott LJ, Scuteri A, Sharp S, Sijbrands E, Smit JH, Song K, Steinthorsdottir V, Stringham HM, Tuomi T, Tuomilehto J, Uitterlinden AG, Voight BF, Waterworth D, Wichmann HE, Willemsen G, Witteman JC, Yuan X, Zhao JH, Zeggini E, Schlessinger D, Sandhu M, Boomsma DI, Uda M, Spector TD, Penninx BW, Altshuler D, Vollenweider P, Jarvelin MR, Lakatta E, Waeber G, Fox CS, Peltonen L, Groop LC, Mooser V, Cupples LA, Thorsteinsdottir U, Boehnke M, Barroso I, Van Duijn C, Dupuis J, Watanabe RM, Stefansson K, McCarthy MI, Wareham NJ, Meigs JB, Abecasis GR. Variants in MTNR1B influence fasting glucose levels. Nat Genet. 2009 Jan;41(1):77-81. Epub 2008 Dec 7.

298    Puk O, Dalke C, Calzada-Wack J, Ahmad N, Klaften M, Wagner S, Hrabé de Angelis M, Graw J. Reduced corneal thickness and enlarged anterior chamber in a novel ColVIIIa2G257D mutant mouse. Invest Ophthalmol Vis Sci. 2009 Dec;50(12):5653-61. PMID: 19578028

297    Puk O, Esposito I, Söker T, Löster J, Budde B, Nürnberg P, Michel-Soewarto D, Fuchs H, Wolf E, Hrabé de Angelis M, Graw J. A new Fgf10 mutation in the mouse leads to atrophy of the harderian gland and slit-eye phenotype in heterozygotes: a novel model for dry-eye disease? Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4311-8. PMID: 19407009

296    Rakovic A, Stiller B, Djarmati A, Flaquer A, Freudenberg J, Toliat M-R, Linnebank M, Kostic V, Lohmann K, Paus S, Nürnberg P, Kubisch C, Klein C, Wüllner U, Ramirez A. Genetic association study of the P-type ATPase ATP13A2 in late onset Parkinson disease. Mov Disord 2009;24:429-433.

295    Ramm P, Couillard-Despres S, Plötz S, Rivera FJ, Krampert M, Lehner B, Kremer  W, Bogdahn U, Kalbitzer HR, Aigner L. A nuclear magnetic resonance biomarker for neural progenitor cells: is it all neurogenesis? Stem Cells. 2009 Feb;27(2):420-3. PubMed PMID: 18988707.

294    Rao AV, Valk PJ, Metzeler KH, Acharya CR, Tuchman SA, Stevenson MM, Rizzieri DA, Delwel R, Buske C, Bohlander SK, Potti A, Löwenberg B. Age-specific differences in oncogenic pathway dysregulation and anthracycline sensitivity in patients with acute myeloid leukemia. J Clin Oncol. 2009 Nov 20;27(33):5580-6. Epub 2009 Oct 26.

293    Rathkolb B, Noyes HA, Brass A, Dark P, Fuchs H, Gailus-Durner V, Gibson J, Hrabé de Angelis M, Ogugo M, Iraqi F, Kemp SJ, Naessens J, Pope ME, Wolf E, Agaba M. Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection. Infect Immun. 2009 Sep;77(9):3948-57. doi:10.1128/IAI.00658-09

292    Rediger A, Tarnow P, Bickenbach A, Schaefer M, Krude H, Gruters A, Biebermann H. Heterodimerization of Hypothalamic G-Protein-Coupled Receptors Involved in Weight Regulation. Obes Facts 2(2): 80-86, 2009.

291    Reindl C, Quentmeier H, Petropoulos K, Greif PA, Benthaus T, Argiropoulos B, Mellert G, Vempati S, Duyster J, Buske C, Bohlander SK, Humphries KR, Hiddemann W, Spiekermann K. CBL exon 8/9 mutants activate the FLT3 pathway and cluster in core binding factor/11q deletion acute myeloid leukemia/myelodysplastic syndrome subtypes. Clin Cancer Res. 2009 Apr 1;15(7):2238-47. Epub 2009 Mar 10.

290    Reinehr T, Hebebrand J, Friedel S, Toschke AM, Brumm H, Biebermann H, Hinney A. Lifestyle intervention in obese children with variations in the melanocortin 4 receptor gene. Obesity (Silver Spring). 17(2): 382-9, 2009

289    Reinehr T, Hinney A, Toschke AM, Hebebrand J. Aggravating effect of INSIG2 andFTO on overweight reduction in a one-year lifestyle intervention. Arch Dis Child.2009 Dec;94(12):965-7. Epub 2009 Feb 17. PubMed PMID: 19224890.

288    Remke M, Pfister S, Kox C, Toedt G, Becker N, Benner A, Werft W, Breit S, Liu S, Engel F, Wittmann A, Zimmermann M, Stanulla M, Schrappe M, Ludwig WD, Bartram CR, Radlwimmer B, Muckenthaler MU, Lichter P, Kulozik AE:High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response. Blood, 2009; 114: 1053-1062.

287    Renner S., W. van Otterlo, M. Dominguez Seoane, S. Möcklinghoff, B. Hofmann, S. Wetzel, A. Schuffenhauer, P. Ertl, T. Oprea, D. Steinhilber, L. Brunsveld, D. Rauh, H. Waldmann. (2009). Bioactivity-Guided Mapping of and Navigation in Chemical Space. Nat Chem Biol, 2009, 5(8):585-92

286    Ridder DA, Bulashevska S, Chaitanya GV, Babu PP, Brors B, Eils R, Schneider A,Schwaninger M. Discovery of transcriptional programs in cerebral ischemia by insilico promoter analysis. Brain Res. 2009 May 26;1272:3-13.

285    Rivera FJ, Siebzehnrubl FA, Kandasamy M, Couillard-Despres S, Caioni M, Poehler AM, Berninger B, Sandner B, Bogdahn U, Goetz M, Bluemcke I, Weidner N, Aigner L. Mesenchymal stem cells promote oligodendroglial differentiation in hippocampal slice cultures. Cell Physiol Biochem. 2009;24(3-4):317-24. Epub 2009  Aug 3. PubMed PMID: 19710546.

284    Rochet N, Sterzing F, Jensen AD, Dinkel J, Herfarth KK, Schubert K, Eichbaum MH, Schneeweiss A, Sohn C, Debus J, Harms W. Intensity-modulated whole abdominal radiotherapy after surgery and carboplatin/taxane chemotherapy for advanced ovarian cancer: phase I study. Int J Radiat Oncol Biol Phys 2009 [Epub ahead of print].

283    Rodríguez E, Baurecht H, Herberich E, Wagenpfeil S, Brown SJ, Cordell HJ, Irvine AD, Weidinger S. Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease. J Allergy Clin Immunol. 2009 Jun;123(6):1361-70.e7.

282    Rom J, von Minckwitz G, Marmé F, Ataseven B, Kozian D, Sievert M, Schlehe B, Schuetz F, Scharf A, Kaufmann M, Sohn C, Schneeweiss A. Phase I study of apoptosis gene modulation with oblimersen within preoperative chemotherapy in patients with primary breast cancer. Ann Oncol. 2009 Nov;20(11):1829-35. Epub 2009 Jul 15.

281    Rosenstiel P, Schreiber S. NOD-like receptors--pivotal guardians of the immunological integrity of barrier organs. Adv Exp Med Biol. 2009;653:35-47. Review.

280    Rosenstiel P, Sina C, Franke A, Schreiber S. Towards a molecular risk map--recent advances on the etiology of inflammatory bowel disease. Semin Immunol. 2009 Dec;21(6):334-45. Epub 2009 Nov 17. Review

279    Rubio-Aliaga I, Przemeck GK, Fuchs H, Gailus-Durner V, Adler T, Hans W, Horsch M, Rathkolb B, Rozman J, Schrewe A, Wagner S, Hölter SM, Becker L, Klopstock T, Wurst W, Wolf E, Klingenspor M, Ivandic BT, Busch DH, Beckers J, Hrabé de Angelis M. Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. PLoS One. 2009 Jun 29;4(6):e6054. doi:10.1371/journal.pone.0006054

278    Rujescu D, Ingason A, Cichon S, Pietiläinen OP, Barnes MR, Toulopoulou T, Picchioni M, Vassos E, Ettinger U, Bramon E, Murray R, Ruggeri M, Tosato S, Bonetto C, Steinberg S, Sigurdsson E, Sigmundsson T, Petursson H, Gylfason A, Olason PI, Hardarsson G, Jonsdottir GA, Gustafsson O, Fossdal R, Giegling I, Möller HJ, Hartmann AM, Hoffmann P, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Djurovic S, Melle I, Andreassen OA, Hansen T, Werge T, Kiemeney LA, Franke B, Veltman J, Buizer-Voskamp JE; GROUP Investigators, Sabatti C, Ophoff RA, Rietschel M, Nöthen MM, Stefansson K, Peltonen L, St Clair D, Stefansson H, Collier DA. Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet. 2009 Mar 1;18(5):988-96. doi: 10.1093/hmg/ddn351

277    Ruschke K, Ebelt H, Klöting N, Boettger T, Raum K, Blüher M, Braun T.Defective peripheral nerve development is linked to abnormal architecture and metabolic activity of adipose tissue in Nscl-2 mutant mice. PLoS One. 2009;4(5):e5516.

276    Sahin O, Froehlich H, Löbke C, Korf U, Burmester S, Majety M, Mattern J, Schupp I, Chaouiya C, Thieffry D, Poustka A, Wiemann S, Beissbarth T, Arlt D. Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance. BMC Syst Biol. 2009 Jan 1;3:1.

275    Sahin O, Wiemann S. Functional genomics and proteomics approaches to study the ERBB network in cancer. FEBS Lett. 2009 Jun 5;583(11):1766-71. Epub 2009 Mar 20.

274    Sahin, O. et al. (2009). Modeling of ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance. BMC Systems Biology 2009, 3, 1.

273    Saint-Martin C, Gauvain G, Teodorescu G, Gourfinkel-An I, Fedirko E, Weber YG, Maljevic S, Ernst JP, Garcia-Olivares J, Fahlke Ch, Nabbout R, LeGuern E, Lerche H, Poncer JC, Depienne C. Two novel CLCN2 mutations accelerating Cl- channel deactivation are associated with idiopathic generalized epilepsy. Hum Mut 2009;30:397-405

272    Salanti G, Southam L, Altshuler D, Ardlie K, Barroso I, Boehnke M, Cornelis MC, Frayling TM, Grallert H, Grarup N, Groop L, Hansen T, Hattersley AT, Hu FB, Hveem K, Illig T, Kuusisto J, Laakso M, Langenberg C, Lyssenko V, McCarthy MI, Morris A, Morris AD, Palmer CN, Payne F, Platou CG, Scott LJ, Voight BF, Wareham NJ, Zeggini E, Ioannidis JP. Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol. 2009 Sep 1;170(5):537-45. Epub 2009 Jul 14.

271    Samani NJ, Deloukas P, Erdmann J, Hengstenberg C, Kuulasmaa K, McGinnis R, Schunkert H, Soranzo N, Thompson J, Tiret L, Ziegler A. Large scale association analysis of novelgenetic loci for coronary artery disease. Coronary Artery Disease Consortium

270    Schaefer AS, Richter GM, Groessner-Schreiber B, Noack B, Nothnagel M, El Mokhtari NE, Loos BG, Jepsen S, Schreiber S. Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis. PLoS Genet. 2009 Feb;5(2):e1000378

269    Schafmayer C, Buch S, Völzke H, von Schönfels W, Egberts JH, Schniewind B, Brosch M, Ruether A, Franke A, Mathiak M, Sipos B, Henopp T, Catalcali J, Hellmig S, Elsharawy A, Katalinic A, Lerch MM, John U, Fölsch UR, Fändrich F, Kalthoff H, Schreiber S, Krawczak M, Tepel J, Hampe J. Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample. Int J Cancer. 2009 Jan 1;124(1):75-80.

268    Schardt DM, Erk S, Nüsser C, Nöthen MM, Cichon S, Rietschel M, Treutlein J, Goschke T, Walter H. Volition diminishes genetically mediated amygdala hyperreactivity. NeuroImage Volume 53, Issue 3, 15 November 2010, Pages 943-951

267    Schedel M, Frei R, Bieli C, Cameron L, Adamski J, Lauener R, Kabesch M. AnIgE-associated polymorphism in STAT6 alters NF-kappaB binding, STAT6 romoter activity, and mRNA expression. J Allergy Clin Immunol. 2009 Sep;124(3):583-9, 589.e1-6. Epub 2009 Aug 8. PubMed PMID: 19665768.

266    Scherag A, Hebebrand J, Schäfer H, Müller HH. Flexible designs for genomewide association studies. Biometrics. 2009; 65:815-21.

265    Scherer, D., D. Hassel, R. Bloehs, E. Zitron, K. von Lowenstern, C. Seyler, D. Thomas, F. Konrad, H.F. Burgers, G. Seemann, W. Rottbauer, H.A. Katus, C.A. Karle, and E.P. Scholz.Selective noradrenaline reuptake inhibitor atomoxetine directly blocks hERG currents. Br J Pharmacol 156:226-236. 2009.

264    Scherneck S, Nestler M, Vogel H, Blüher M, Block MD, Mauricio MB, Herzig S, Schulz N, Teichert M, Tischer M, Al-Hasani H, Kluge R, Schürmann A, and Joost HG. Positional cloning of zinc finger domain transcription factor Zfp69, a candidate gene for obesity-associated diabetes contributed by mouse locus Nidd/SJL. PLoS Genetics  5:e1000541 (2009).

263    Schimmelmann BG, Friedel S, Nguyen TT, Sauer S, Ganz Vogel CI, Konrad K, Wilhelm C, Sinzig J, Renner TJ, Romanos M, Palmason H, Dempfle A, Walitza S, Freitag C, Meyer J, Linder M, Schäfer H, Warnke A, Lesch KP, Herpertz-Dahlman B, Hinney A, Hebebrand J. J Psychiatr Res. 2009 Jul;43(10):941-5. Epub 2009 Feb 14.

262    Schleinitz D, Klöting N, Körner A, Berndt J, Reichenbächer M, Tönjes A, Ruschke K, Böttcher Y, Dietrich K, Enigk B, Filz M, Schön MR, Jenkner J, Kiess W, Stumvoll M, Blüher M, Kovacs P. Effect of Genetic Variation in the Human Fatty Acid Synthase Gene (FASN) on Obesity and Fat Depot-Specific mRNA Expression. Obesity (Silver Spring). 2009 Oct 29.

261    Schmitt AO, Bortfeld R, Neuschl C, Brockmann GA. RandoMate - a program for the generation of random mating schemes for small laboratory animals.  Mamm. Genome 2009; 20(5):321-325

260    Schmitt AO, Schuchhardt J, Brockmann GA. The action of key factors in protein evolution at high temporal resolution. PLoS ONE. 2009; 4(3):e4821. doi:10.1371/journal.pone.0004821

259    Schnabel RB, Baumert J, Barbalic M, Dupuis J, Ellinor PT, Durda P, Dehghan A, Bis JC, Illig T, Morrison AC, Jenny NS, Keaney JF Jr, Gieger C, Tilley C, Yamamoto JF, Khuseyinova N, Heiss G, Doyle M, Blankenberg S, Herder C, Walston JD, Zhu Y, Vasan RS, Klopp N, Boerwinkle E, Larson MG, Psaty BM, Peters A, Ballantyne CM, Witteman JC, Hoogeveen RC, Benjamin EJ, Koenig W, Tracy RP. Duffy antigen receptor for chemokines polymorphism regulates circulating concentrations of MCP-1.

258    Scholz SW, Houlden H, Schulte C, Sharma M, Li A, Berg D, Melchers A, Paudel R, Gibbs JR, Simon-Sanchez J, Paisan-Ruiz C, Bras J, Ding J, Chen H, Traynor BJ, Arepalli S, Zonozi RR, Revesz T, Holton J, Wood N, Lees A, Oertel W, Wullner U, Goldwurm S, Pellecchia MT, Illig T, Riess O, Fernandez HH, Rodriguez RL, Okun MS, Poewe W, Wenning GK, Hardy JA, Singleton AB, Gasser T. SNCA variants are associated with increased risk for multiple system atrophy. Ann Neurol. 2009 Mar 18;65(5):610-4.

257    Scholz, E.P., N. Niemer, D. Hassel, E. Zitron, H.F. Burgers, R. Bloehs, C. Seyler, D. Scherer, D. Thomas, S. Kathofer, H.A. Katus, W. Rottbauer, and C.A. Karle. (2009). Biophysical properties of zebrafish ether-a-go-go related gene potassium channels. Biochem Biophys Res Commun 381:159-164.

256    Schubert W, Gieseler A, Krusche A, Hillert R. Toponome mapping in prostate cancer: detection of 2000 cell surface protein clusters in a single tissue section and cell type specific annotation by using a three symbol code. J Proteome Res. 2009 Jun;8(6):2696-707. doi:10.1021/pr800944f

255    Schuetz F, Ehlert K, Ge Y, Schneeweiss A, Rom J, Inzkirweli N, Sohn C, Schirrmacher V, Beckhove P. Treatment of advanced metastasized breast cancer with bone marrow-derived tumour-reactive memory T cells: a pilot clinical study. Cancer Immunol Immunother. 2009 Jun;58(6):887-900. Epub 2008 Nov 8.

254    Schüffler P, Mikeska T, Waha A, Lengauer T, Bock C. MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays. Genome Biol. 2009;10(10):R105. Epub 2009 Oct 5

253    Schulte C, Synofzik M, Gasser T, Schols L. Ataxia with ophthalmoplegia or sensory neuropathy is frequently caused by POLG mutations. Neurology. 2009 Sep 15;73(11):898-900.

252    Schulze TG, Detera-Wadleigh SD, Akula N, Gupta A, Kassem L, Steele J, Pearl J, Strohmaier J, Breuer R, Schwarz M, Propping P, Nöthen MM, Cichon S, Schumacher J; NIMH Genetics Initiative Bipolar Disorder Consortium, Rietschel M, McMahon FJ. Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder. Mol Psychiatry. 2009 May;14(5):487-91. doi:10.1038/mp.2008.134

251    Schumacher A, Friedrich P, Diehl-Schmid J, Ibach B, Perneczky R, Eisele T, Vukovich R, Foerstl H, Riemenschneider M. No association of TDP-43 with sporadic frontotemporal dementia. Neurobiol Aging. 2009;30(1):157-9.

250    Schumacher J, Laje G, Abou Jamra R, Becker T, Muhleisen TW, Vasilescu C, Mattheisen M, Herms S, Hoffmann P, Hillmer AM, Georgi A, Herold C, Schulze TG, Propping P, Rietschel M, McMahon FJ, Nothen MM, Cichon S. The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations. Hum Mol Genet. 2009 Jul 15;18(14):2719-27. doi:10.1093/hmg/ddp204

249    Schwanhäusser B, Gossen M, Dittmar G, Selbach M. Global analysis of cellular protein translation by pulsed SILAC. Proteomics. 2009 Jan; 9(1):205-209. doi 10.1002/pmic.200800275

248    Sharma CM, Vogel J. Experimental approaches for the discovery and characterization of regulatory small RNA. Curr Opin Microbiol. 2009 Oct;12(5):536-46.

247    Sharma M, Lichtner P,  Krüger R, Berg D, Schulte C,  Illig T, Riess O, Gasser T. Further delineation of the association signal on chromosome 5 from the first whole genome association study in Parkinson's disease. Neurobiol Aging. 2009;30:706-9.

246    Siddiqui RA, Sauermann U, Altmüller J, Fritzer E, Nothnagel M, Dalibor N, Fellay J, Kaup FJ, Stahl-Hennig C, Nürnberg P, Krawczak M, Platzer M. X chromosomal variation is associated with slow progression to AIDS in HIV-1-infected women. Am J Hum Genet. 2009 Aug;85(2):228-39.

245    Sidransky E, Nalls MA, Aasly JO, Aharon-Peretz J, Annesi G, Barbosa ER, Bar-Shira A, Berg D, Bras J, Brice A, Chen CM, Clark LN, Condroyer C, De Marco EV, Durr A, Eblan MJ, Fahn S, Farrer MJ, Fung HC, Gan-Or Z, Gasser T, Gershoni-Baruch R, Giladi N, Griffith A, Gurevich T, Januario C, Kropp P, Lang AE, Lee-Chen GJ, Lesage S, Marder K, Mata IF, Mirelman A, Mitsui J, Mizuta I, Nicoletti G, Oliveira C, Ottman R, Orr-Urtreger A, Pereira LV, Quattrone A, Rogaeva E, Rolfs A, Rosenbaum H, Rozenberg R, Samii A, Samaddar T, Schulte C, Sharma M, Singleton A, Spitz M, Tan EK, Tayebi N, Toda T, Troiano AR, Tsuji S, Wittstock M, Wolfsberg TG, Wu YR, Zabetian CP, Zhao Y, Ziegler SG. Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease. N Engl J Med. 2009 Oct 22;361(17):1651-61.

244    Silberstein S, Vogl AM, Refojo D, Senin SA, Wurst W, Holsboer F, Deussing JM, Arzt E. Amygdaloid pERK1/2 in corticotropin-releasing hormone overexpressing mice under basal and acute stress conditions. Neuroscience. 2009 Mar 17;159(2):610-617.

243    Simard, J.R., and Rauh, D. (2009). Chemical and structural biology to direct the repurposing of sulindac. ChemMedChem 4, 2009, 1793-1795.

242    Simard, J.R., Getlik, M., Grutter, C., Pawar, V., Wulfert, S., Rabiller, M., and Rauh, D. (2009). Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors. J Am Chem Soc 131, 2009, 13286-13296.

241    Simard, J.R., Grutter, C., Pawar, V., Aust, B., Wolf, A., Rabiller, M., Wulfert, S., Robubi, A., Kluter, S., Ottmann, C., et al. (2009). High-throughput screening to identify inhibitors which stabilize inactive kinase conformations in p38alpha. J Am Chem Soc 131, 2009, 18478-18488.

240    Simard, J.R., S. Klüter, C. Grütter, M. Rabiller, H.B. Rode, D. Rauh. (2009). A new screening assay for allosteric inhibitors of cSrc. Nat Chem Biol, 2009, 5(6):394-6

239    Simon-Sanchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, Berg D, Paisan-Ruiz C, Lichtner P, Scholz SW, Hernandez DG, Kruger R, Federoff M, Klein C, Goate A, Perlmutter J, Bonin M, Nalls MA, Illig T, Gieger C, Houlden H, Steffens M, Okun MS, Racette BA, Cookson MR, Foote KD, Fernandez HH, Traynor BJ, Schreiber S, Arepalli S, Zonozi R, Gwinn K, van der Brug M, Lopez G, Chanock SJ, Schatzkin A, Park Y, Hollenbeck A, Gao J, Huang X, Wood NW, Lorenz D, Deuschl G, Chen H, Riess O, Hardy JA, Singleton AB, Gasser T. Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet. 2009 Dec;41(12):1308-12.

238    Sina C, Gavrilova O, Förster M, Till A, Derer S, Hildebrand F, Raabe B, Chalaris A, Scheller J, Rehmann A, Franke A, Ott S, Häsler R, Nikolaus S, Fölsch UR, Rose-John S, Jiang HP, Li J, Schreiber S, Rosenstiel P. G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation. J Immunol. 2009 Dec 1;183(11):7514-22. Epub 2009 Nov 16.

237    Sinha R, Nikolajewa S, Szafranski K, Hiller M, Jahn N, Huse K, Platzer M, Backofen R. Accurate prediction of NAGNAG alternative splicing. Nucleic Acids Res. 2009 ,37:3569.

236    Sipos B, Frank S, Gress T, Hahn S, Klöppel G. Pancreatic intraepithelial neoplasia revisited and updated. Pancreatology. 2009;9(1-2):45-54.

235    Sittka A, Sharma CM, Rolle K, Vogel J. Deep sequencing of Salmonella RNA associated with heterologous Hfq proteins in vivo reveals small RNAs as a major target class and identifies RNA processing phenotypes. RNA Biol. 2009 Jul;6(3):266-75.

234    Soehn AS, Pham TT, Schaeferhoff K, Floss T, Vogt-Weisenhorn DM, Wurst W, Bonin M, and Riess O. Periphilin Is Strongly Expressed in the Murine Nervous System and Is Indispensable for Murine Development. Genesis. 2009 Oct;47(10):697-707.

233    Sohns M, Rosenberger A, Bickeböller. Integration of a priori gene set information into genome-wide association studies. H. BMC Proc. 2009 Dec 15;3 Suppl 7:S95. PMID: 20018092

232    Soranzo N, Rendon A, Gieger C, Jones CI, Watkins NA, Menzel S, Döring A, Stephens J, Prokisch H, Erber W, Potter SC, Bray SL, Burns P, Jolley J, Falchi M, Kühnel B, Erdmann J, Schunkert H, Samani NJ, Illig T, Garner SF, Rankin A, Meisinger C, Bradley JR, Thein SL, Goodall AH, Spector TD, Deloukas P, Ouwehand WH. A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function.

231    Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, Menzel S, Altshuler D, Bradley JR, Bumpstead S, Burnett MS, Devaney J, Döring A, Elosua R, Epstein SE, Erber W, Falchi M, Garner SF, Ghori MJ, Goodall AH, Gwilliam R, Hakonarson HH, Hall AS, Hammond N, Hengstenberg C, Illig T, König IR, Knouff CW, McPherson R, Melander O, Mooser V, Nauck M, Nieminen MS, O'Donnell CJ, Peltonen L, Potter SC, Prokisch H, Rader DJ, Rice CM, Roberts R, Salomaa V, Sambrook J, Schreiber S, Schunkert H, Schwartz SM, Serbanovic-Canic J, Sinisalo J, Siscovick DS, Stark K, Surakka I, Stephens J, Thompson JR, Völker U, Völzke H, Watkins NA, Wells GA, Wichmann HE, Van Heel DA, Tyler-Smith C, Thein SL, Kathiresan S, Perola M, Reilly MP, Stewart AF, Erdmann J, Samani NJ, Meisinger C, Greinacher A, Deloukas P, Ouwehand WH, Gieger C. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet. 2009 Nov; 41(11):1182-90.

230    Soria JC, Shepherd FA, Douillard JY, Wolf J, Giaccone G, Crino L, Cappuzzo F, Sharma S, Gross SH, Dimitrijevic S, Di Scala L, Gardner H, Nogova L, Papadimitrakopoulou V. Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors. Ann Oncol. 2009 Oct;20(10):1674-81. Epub 2009 Jun 23.

229    Sos ML, Fischer S, Ullrich R, Peifer M, Heuckmann JM, Koker M, Heynck S, Stückrath I, Weiss J, Fischer F, Michel K, Goel A, Regales L, Politi KA, Perera S, Getlik M, Heukamp LC, Ansén S, Zander T, Beroukhim R, Kashkar H, Shokat KM, Sellers WR, Rauh D, Orr C, Hoeflich KP, Friedman L, Wong KK, Pao W, Thomas RK.Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer. Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43):18351-6

228    Sos ML, Koker M, Weir BA, Heynck S, Rabinovsky R, Zander T, Seeger JM, Weiss J, Fischer F, Frommolt P, Michel K, Peifer M, Mermel C, Girard L, Peyton M, Gazdar AF, Minna JD, Garraway LA, Kashkar H, Pao W, Meyerson M, Thomas RK. PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR. Cancer Res. 2009 Apr 15; 69(8):3256-61.

227    Sos ML, Michel K, Zander T, Weiss J, Frommolt P, Peifer M, Li D, Ullrich R, Koker M, Fischer F, Shimamura T, Rauh D, Mermel C, Fischer S, Stückrath I, Heynck S, Beroukhim R, Lin W, Winckler W, Shah K, LaFramboise T, Moriarty WF, Hanna M, Tolosi L, Rahnenführer J, Verhaak R, Chiang D, Getz G, Hellmich M, Wolf J, Girard L, Peyton M, Weir BA, Chen TH, Greulich H, Barretina J, Shapiro GI, Garraway LA, Gazdar AF, Minna JD, Meyerson M, Wong KK, Thomas RK. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest. 2009 Jun; 119(6): 1727-40. doi: 10.1172/JCI37127. Epub 2009 May 18.

226    Spanagel R; Alcoholism ? a systems approach from molecular physiology to behavior. Physiol Rev (2009) 89, 649-705

225    Sprenger T, Rothe H, Homayounfar K, Beissbarth T, Ghadimi BM, Becker H, Liersch T. Preoperative Chemoradiotherapy Does Not Necessarily Reduce Lymph Node Retrieval in Rectal Cancer Specimens-Results from a Prospective Evaluation with Extensive Pathological Work-up. J Gastrointest Surg. 2009.

224    Srivastava B, P.Blazejewska, M. Heßmann, D. Bruder, R. Geffers, S. Mauel, A. D. Gruber, K. Schughart. (2009) Host genetic background strongly influences the response to influenza A virus infections. PLoSONE, 4, e4857.

223    Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Böttcher Y, Olesen J, Breuer R, Möller HJ, Giegling I, Rasmussen HB, Timm S, Mattheisen M, Bitter I, Réthelyi JM, Magnusdottir BB, Sigmundsson T, Olason P, Masson G, Gulcher JR, Haraldsson M, Fossdal R, Thorgeirsson TE, Thorsteinsdottir U, Ruggeri M, Tosato S, Franke B, Strengman E, Kiemeney LA; Genetic Risk and Outcome in Psychosis (GROUP), Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, Ge D, Yoon JL, Shianna KV, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Carracedo A, Arango C, Costas J, Jönsson EG, Terenius L, Agartz I, Petursson H, Nöthen MM, Rietschel M, Matthews PM, Muglia P, Peltonen L, St Clair D, Goldstein DB, Stefansson K, Collier DA. Common variants conferring risk of schizophrenia. Nature.  2009 Aug 6;460(7256):744-7. doi:10.1038/nature08186

222    Steubesand N, Kiehne K, Brunke G, Pahl R, Reiss K, Herzig KH, Schubert S, Schreiber S, Fölsch UR, Rosenstiel P, Arlt A. The expression of the beta-defensins hBD-2 and hBD-3 is differentially regulated by NF-kappaB and MAPK/AP-1 pathways in an in vitro model of Candida esophagitis. BMC Immunol. 2009 Jun 12;10:36.

221    Streckfuss-Bömeke K, Vlasov A, Yin D, Hülsmann S, Nayernia K, Engel W, Hasenfuss G, Guan K. Generation of functional neurons and glia from multipotent adult mouse germline stem cells. Stem Cell Res. 2009;2:139-154

220    Stritzke J, Linsel-Nitschke P, Markus MR, Mayer B, Lieb W, Luchner A, Döring A, Koenig W, Keil U, Hense HW, Schunkert H; MONICA/KORA Investigators. Association between degenerative aortic valve disease and long-term exposure to cardiovascular risk factors: results of the longitudinal population-based KORA/MONICA survey. Eur Heart J. 2009 Aug;30(16):2044-53. Epub 2009 Jul 16.

219    Sullivan PF, de Geus EJ, Willemsen G, James MR, Smit JH, Zandbelt T, Arolt V, Baune BT, Blackwood D, Cichon S, Coventry WL, Domschke K, Farmer A, Fava M, Gordon SD, He Q, Heath AC, Heutink P, Holsboer F, Hoogendijk WJ, Hottenga JJ, Hu Y, Kohli M, Lin D, Lucae S, Macintyre DJ, Maier W, McGhee KA, McGuffin P, Montgomery GW, Muir WJ, Nolen WA, Nöthen MM, Perlis RH, Pirlo K, Posthuma D, Rietschel M, Rizzu P, Schosser A, Smit AB, Smoller JW, Tzeng JY, van Dyck R, Verhage M, Zitman FG, Martin NG, Wray NR, Boomsma DI, Penninx BW. Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo. Mol Psychiatry. 2009 Apr;14(4):359-75. doi:10.1038/mp.2008.125

218    Suls A*, Mullen SA*, Weber YG*, K Verhaert K, Ceulemans B, R Guerrini R, Wuttke TV, Salvo-Vargas A, Deprez L, Claes LRF, Jordanova A, Berkovic SF, Lerche H, De Jonghe P, Scheffer IE. Early onset absence epilepsy due to mutations in the glucose transporter GLUT1. Ann Neurol 2009; 66:415-9, *contributed equally

217    Supper J, Spangenberg L, Planatscher H, Dräger A, Schröder A, and Zell A: BowTieBuilder: modeling signal transduction pathways, BMC Systems Biology 2009, (30 June 2009). doi:10.1186/1752-0509-3-67

216    Suttner K, Rosenstiel P, Depner M, Schedel M, Pinto LA, Ruether A, Adamski J, Klopp N, Illig T, Vogelberg C, Schreiber S, von Mutius E, Kabesch M. TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants. J Allergy Clin Immunol. 2009 May;123(5):1062-8, 1068.e1-8. Epub 2009 Apr 10.

215    Suttner K, Ruoss I, Rosenstiel P, Depner M, Pinto LA, Schedel M, Adamski J, Illig T, Schreiber S, von Mutius E, Kabesch M. HLX1 gene variants influence the development of childhood asthma. J Allergy Clin Immunol. 2009 Jan;123(1):82-88.e6.

214    Szodorai A, KuanY-H, Hunzelmann S, Engel U, Sakane A, Sasaki T, Takai Y, Kirsch J, Müller U, Beyreuther K, Brady S, Morfini G, Kins S (2009) APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. J Neurosci 2009; 29: 14534-44

213    Tamura T, Sone M, Yamashita M, Wanker EE, Okazawa H. Glial cell lineage expression of mutant ataxin-1 and huntingtin induces developmental and late-onset neuronal pathologies in Drosophila models. PLoS ONE. 2009 Jan; 4 (1):e4262. doi 10.1371/journal.pone.0004262

212    Tang W, Ehrlich I, Wolff SB, Michalski AM, Wölfl S, Hasan MT, Lüthi A, Sprengel R. Faithful expression of multiple proteins via 2A-peptide self-processing: a versatile and reliable method for manipulating brain circuits. J Neurosci. 2009 Jul 8;29(27):8621-9. No abstract available

211    Temple G, Gerhard DS, Rasooly R, Feingold EA, Good PJ, Robinson C, Mandich A, Derge JG, Lewis J, Shoaf D, Collins FS, Jang W, Wagner L, Shenmen CM, Misquitta L, Schaefer CF, Buetow KH, Bonner TI, Yankie L, Ward M, Phan L, Astashyn A, Brown G, Farrell C, Hart J, Landrum M, Maidak BL, Murphy M, Murphy T, Rajput B, Riddick L, Webb D, Weber J, Wu W, Pruitt KD, Maglott D, Siepel A, Brejova B, Diekhans M, Harte R, Baertsch R, Kent J, Haussler D, Brent M, Langton L, Comstock CL, Stevens M, Wei C, van Baren MJ, Salehi-Ashtiani K, Murray RR, Ghamsari L, Mello E, Lin C, Pennacchio C, Schreiber K, Shapiro N, Marsh A, Pardes E, Moore T, Lebeau A, Muratet M, Simmons B, Kloske D, Sieja S, Hudson J, Sethupathy P, Brownstein M, Bhat N, Lazar J, Jacob H, Gruber CE, Smith MR, McPherson J, Garcia AM, Gunaratne PH, Wu J, Muzny D, Gibbs RA, Young AC, Bouffard GG, Blakesley RW, Mullikin J, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Hirst M, Zeng T, Tse K, Moksa M, Deng M, Ma K, Mah D, Pang J, Taylor G, Chuah E, Deng A, Fichter K, Go A, Lee S, Wang J, Griffith M, Morin R, Moore RA, Mayo M, Munro S, Wagner S, Jones SJ, Holt RA, Marra MA, Lu S, Yang S, Hartigan J, Graf M, Wagner R, Letovksy S, Pulido JC, Robison K, Esposito D, Hartley J, Wall VE, Hopkins RF, Ohara O, Wiemann S. MGC Project Team.  The completion of the Mammalian Gene Collection (MGC). Genome Res. 2009 Dec;19(12):2324-33. Epub 2009 Sep 18.

210    Theis M, Slabicki M, Junqueira M, Paszkowski-Rogacz M, Sontheimer J, Kittler R, Heninger AK, Glatter T, Kruusmaa K, Poser I, Hyman AA, Pisabarro MT, Gstaiger M, Aebersold R, Shevchenko A, Buchholz F.Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division. EMBO J. 2009 May 20;28(10):1453-65. Epub 2009 Apr 23.

209    Theis, M; Paszkowski-Rogacz, M; Buchholz, FSKAnking with Ska3 Essential role of Ska3 in cell division revealed by combined phenotypic profiling. Cell Cycle. 2009 Nov 1;8(21):3435-7. Epub 2009 Nov 16.

208    Theissen J, Boensch M, Spitz R, Betts D, Stegmaier S, Christiansen H, Niggli F, Schilling F, Schwab M, Simon T, Westermann F, Berthold F, Hero B. Heterogeneity of the MYCN oncogene in neuroblastoma. Clin Cancer Res, 2009. 15(6): p. 2085-90. IF 6.25.

207    Thoene S, Rawat VP, Heilmeier B, Hoster E, Metzeler KH, Herold T, Hiddemann W, Gökbuget N, Hoelzer D, Bohlander SK, Feuring-Buske M, Buske C. The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia. Leukemia. 2009 Apr;23(4):649-55. Epub 2009 Jan 22.

206    Thoeringer CK, Ripke S, Unschuld PG, Lucae S, Ising M, Bettecken T, Uhr M,Keck ME, Mueller-Myhsok B, Holsboer F, Binder EB, Erhardt A. The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders. J Neural Transm. 2009 Jun;116(6):649-57. PMID: 18607529

205    Tikka-Kleemola P, Kaunisto MA, Hämäläinen E, Todt U, Göbel H, Kaprio J, Kubisch C, Färkkilä M, Palotie A, Wessman M, Kallela M. Genetic association study of endothelin-1 and its receptors EDNRA and EDNRB in migraine with aura. Cephalalgia. 2009 Nov;29(11):1224-31. PMID: 19558538

204    Tintle N, Lantieri F, Lebrec J, Sohns M, Ballard D, Bickeböller H. Inclusion of a priori information in genome-wide association analysis. Genet Epidemiol. 2009;33 Suppl 1:S74-80. PMID: 19924705

203    Todt U, Netzer C, Toliat M, Heinze A, Goebel I, Nürnberg P, Göbel H, Freudenberg J, Kubisch C. New genetic evidence for involvement of the dopamine system in migraine with aura. Hum Genet. 2009 Apr;125(3):265-79. Epub 2009 Jan 17. PMID: 19152006

202    Trégouët DA, König IR, Erdmann J, Munteanu A, Braund PS, Hall AS, Grosshennig A, Linsel-Nitschke P, Perret C, DeSuremain M, Meitinger T, Wright BJ, Preuss M, Balmforth AJ, Ball SG, Meisinger C, Germain C, Evans A, Arveiler D, Luc G, Ruidavets JB, Morrison C, van der Harst P, Schreiber S, Neureuther K, Schäfer A, Bugert P, El Mokhtari NE, Schrezenmeir J, Stark K, Rubin D, Wichmann HE, Hengstenberg C, Ouwehand W; Wellcome TrustCase Control Consortium; Cardiogenics Consortium, Ziegler A, Tiret L, Thompson JR, Cambien F, Schunkert H, Samani NJ. Genome-wide haplotype association study identifies the SLC22A3-LPAL2-LPA gene cluster as a risklocus for coronary artery disease. Nat Genet. 2009 Mar;41(3):283-5. Epub 2009 Feb 10

201    Trentin L, Girodan M, Dingermann T, Basso G, te Kronnie G, Marschalek R (2009). Two independent gene signatures in pediatric t(4;11) acute lymphoblastic leukemia patients. Eur J Haematol 83, 406-419.

200    Treutlein J, Cichon S, Ridinger M, Wodarz N, Soyka M, Maier W, Dahmen N, Scherbaum N, Nöthen MM, Steffens M, Wienker TF, Frank J, Wichmann HE, Schreiber S, Jöckel KH,  Sommer W, Gebicke-Haerter P, Kiefer F, Spanagel R, Mann K, Rietschel M (2009) Genome-wide association study of alcohol dependence. Arch Gen Psychiatry. 2009 Jul;66(7):773-84.

199    Treutlein J, Mühleisen TW, Frank J, Mattheisen M, Herms S, Ludwig KU, Treutlein T, Schmael C, Strohmaier J, Bösshenz KV, Breuer R, Paul T, Witt SH, Schulze TG, Schlösser RG, Nenadic I, Sauer H, Becker T, Maier W, Cichon S, Nöthen MM, Rietschel M. Dissection of phenotype reveals possible association between schizophrenia and Glutamate Receptor Delta 1 (GRID1) gene promoter. Schizophr Res. 2009 Jun;111(1-3):123-30. Epub 2009 Apr 5.

198    Tribl F, Asan E, Arzberger T, Tatschner T, Langenfeld E, Meyer HE, Bringmann G, Riederer P, Gerlach M, Marcus K.Identification of L-ferritin in neuromelanin granules of the human substantia nigra - a targeted proteomics approach. Mol Cell Proteomics. 2009 Aug;8(8):1832-8. doi:10.1074/mcp.M900006-MCP200

197    Triola, G., Wetzel, S., Ellinger, B., Koch, M.A., Hubel, K., Rauh, D., and Waldmann, H. ATP competitive inhibitors of D-alanine-D-alanine ligase based on protein kinase inhibitor scaffolds. Bioorg Med Chem 2009, 17, 1079-1087.

196    Tyshchenko N, Hackmann K, Gerlach EM, Neuhann T, Schrock E, Tinschert S. 1.6Mb deletion in chromosome band 3q29 associated with eye abnormalities. Eur J Med Genet. 2009 Mar-Jun;52(2-3):128-130. PMID: 19298871

195    Uhrig M, Ittrich C, Wiedmann V, Knyazev Y, Weninger A, Riemenschneider M,Hartmann T. New Alzheimer amyloid beta responsive genes identified in human neuroblastoma cells by hierarchical clustering. PLoS One. 2009 Aug 26; 4(8):e6779.

194    Uhrig, M., P. Brechlin, O. Jahn, Y. Knyazev, A. Weninger, L. Busia, M. Otto, and T. Hartmann, (2008). Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Abeta42 reduces the differentiation potential. BMC Medicine 6:38 (available 2009)

193    Unschuld PG, Ising M, Specht M, Erhardt A, Ripke S, Heck A, Kloiber S, Straub  V, Brueckl T, Müller-Myhsok B, Holsboer F, Binder EB. Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders. Am J Med Genet B Neuropsychiatr Genet. 2009 Dec 5;150B(8):1100-9. PubMed PMID: 19229853.

192    Untch M, Möbus V, Kuhn W, Muck BR, Thomssen C, Bauerfeind I, Harbeck N, Werner C, Lebeau A, Schneeweiss A, Kahlert S, von Koch F, Petry KU, Wallwiener D, Kreienberg R, Albert US, Lück HJ, Hinke A, Jänicke F, Konecny GE. Intensive dose-dense compared with conventionally scheduled preoperative chemotherapy for high-risk primary breast cancer. J Clin Oncol. 2009 Jun 20;27(18):2938-45. Epub 2009 Apr 13.

191    van Bürck L, Blutke A, Kautz S, Rathkolb B, Klaften M, Wagner S, Kemter E, Hrabé de Angelis M, Wolf E, Aigner B, Wanke R, Herbach N. Phenotypic and pathomorphological characteristics of a novel mutant mouse model for maturity-onset diabetes of the young type 2 (MODY 2). Am J Physiol Endocrinol Metab. Epub 2009 Dec 1. doi:10.1152/ajpendo.00465.2009

190    Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009 Jul 8;302(2):168-78.

189    Vengeliene V, Celerier E, Chaskiel L, Penzo F, Spanagel R  Compulsive drug and food taking behaviour in rodents. Addict Biol (2009) 14:384-96

188    Venkatesan K, Rual JF, Vazquez A, Stelzl U, Lemmens I, Hirozane-Kishikawa T, Hao T, Zenkner M, Xin X, Goh KI, Yildirim MA, Simonis N, Heinzmann K, Gebreab F, Sahalie JM, Cevik S, Simon C, de Smet AS, Dann E, SmolyarA, Vinayagam A, Yu H, Szeto D, Borick H, Dricot A, Klitgord N, Murray RR, Lin C, Lalowski M, Timm J, Rau K, Boone C, Braun P, Cusick ME, Roth FP, Hill DE, Tavernier J, Wanker EE, Barabási AL, Vidal M. An empiricalframework for binary interactome mapping. Nature Methods. 2009 Jan; 6 (1):83-90. doi 10.1038/nmeth.1280

187    Vermeulen J, De Preter K, Naranjo A, Vercruysse L, Van Roy N, Hellemans J, Swerts K, Bravo S, Scaruffi P, Tonini GP, De Bernardi B, Noguera R, Piqueras M, Canete A, Castel V, Janoueix-Lerosey I, Delattre O, Schleiermacher G, Michon J, Combaret V, Fischer M, Oberthuer A, Ambros P, Beiske K, Benard J, Marques B, Rubie H, Kohler J, Pötschger U, Ladenstein R, Hogarty MD, McGrady P, London WB, Laureys G, Speleman F, Vandesompele J.Predicting outcomes for children with neuroblastoma using a multigene-expression signature, a retrospective SIOPEN/COG/GPOH study. Lancet Oncol, 2009, 10(7): 663-671.

186    Vermeulen M, Selbach M. Quantitative proteomics: a tool to assess cell differentiation. Current Opinion in Cell Biology. 2009 Dec; 21(6):761-766. doi 10.1016/j.ceb.2009.09.003

185    Vintonyak, V.V., Antonchick, A.P., Rauh, D., and Waldmann, H. (2009). The therapeutic potential of phosphatase inhibitors. Curr Opin Chem Biol, 2009, 13, 272-283.

184    Vladimirova V, Mikeska T, Waha A, Soerensen N, Xu J, Reynolds PC, Pietsch T. Aberrant methylation and reduced expression of LHX9 in malignant gliomas of childhood. Neoplasia. 2009 Jul;11(7):700-11.

183    Vogel CI, Greene B, Scherag A, Muller TD, Friedel S, Grallert H, Heid IM, Illig T, Wichmann HE, Schafer H, Hebebrand J, Hinney A. Non-replication of an association of CTNNBL1 polymorphisms and obesity in a population of Central European ancestry. BMC Med Genet. 2009 Feb 19;10(1):14.

182    Vogel CI, Scherag A, Brönner G, Nguyen TT, Wang HJ, Grallert H, Bornhorst A,Rosskopf D, Völzke H, Reinehr T, Rief W, Illig T, Wichmann HE, Schäfer H,Hebebrand J, Hinney A. Gastric inhibitory polypeptide receptor: associationanalyses for obesity of several polymorphisms in large study groups. BMC MedGenet. 2009 Mar 2;10:19. PubMed PMID: 19254363; PubMed Central PMCID: PMC2654891.

181    Vogel H, Nestler M, Rüschendorf F, Block MD, Tischer S, Kluge R, Schurmann A, Joost HG, Scherneck S. Characterisation of Nob3, a major quantitative trait locus for obesity and hyperglycaemia on mouse Chromosome 1. Physiol Genomics. 38:226-232 (2009)

180    Vogel J. A rough guide to the non-coding RNA world of Salmonella. Mol Microbiol. 2009 Jan;71(1):1-11.

179    Vogel, B., B. Meder, S. Just, C. Laufer, I. Berger, S. Weber, H.A. Katus, and W. Rottbauer. (2009). In-vivo characterization of human dilated cardiomyopathy genes in zebrafish. Biochem Biophys Res Commun 2009; 390:516-522.

178    von der Goltz C, Vengeliene V, Bilbao A, Perreau-Lenz S, Pawlak C, Mann K, Kiefer F, Spanagel R (2009) Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories. Psychopharmacology 205, 389-97

177    Voth H, Oberthuer A, Simon T, Kahlert Y, Berthold F, Fischer M. Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma. BMC Mol Biol. 2009 Apr 6;10:28

176    Vukovich R, Perneczky R, Drzezga A, Förstl H, Kurz A, Riemenschneider M. Brain metabolic correlates of cerebrospinal fluid beta-amyloid 42 and tau in Alzheimer´s disease. Dement Geriatr Cogn Disord. 2009;27(5):474-80. [Epub 2009 May 12]

175    Waak J, Weber SS, Görner K, Schall C, Ichijo H, Stehle T, Kahle PJ. Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1. J Biol Chem. 2009 May 22;284(21):14245-57.

174    Waak J, Weber SS, Waldenmaier A, Görner K, Alunni-Fabbroni M, Schell H, Vogt-Weisenhorn D, Pham TT, Reumers V, Baekelandt V, Wurst W, Kahle PJ. Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1. FASEB J. 2009 Aug;23(8):2478-89. Epub 2009 Mar 10.

173    Wachter T, Weiss D, Breit S, Gasser T, Kruger R, Gharabaghi A (2009) Severe muscular fasciculations as an uncommon side-effect due to microdefect ofan extension wire in deep brain stimulation. Movement Disord 24(14):2161-2

172    Weber YG, Lerche H. Genetics of paroxysmal dyskinesias. Curr Neurol Neurosci Rep 2009;9:206-11

171    Wegenast-Braun BM, Fulgencio Maisch A, Eicke D, Radde R, Herzig MC, Staufenbiel M, Jucker M, Calhoun ME (2009) Independent effects of intra- and extracellular A on learning-related gene expression. American Journal of Pathology 2009; 175: 271-282

170    Wendt N, Schulz A, Qadri F, Bolbrinker J, Kossmehl P, Winkler K, Stoll M, Vetter R, Kreutz R. Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol. Cardiovasc Res 2009;15;81:618-626

169    Wermter AK, Scherag A, Hölter K, Reichwald K, Lichtner P, Siegfried W, Blundell J, Lawton C, Whybrow S, Stubbs J, Arch JR, Meitinger T, Platzer M, Hinney A, Hebebrand J. Procolipase gene: no association with early-onset obesity or fat intake. Obes Facts. 2009 ;2:40-4.

168    Wetzel S., K. Klein, S. Renner, D. Rauh, T. Oprea, P. Mutzel, H. Waldmann. (2009). Interactive Exploration of Chemical Space with Scaffold Hunter. Nat Chem Biol; 2009; 5(8):581-3

167    Willem M, Lammich S, Haass C. 1. Function, regulation and therapeutic properties of beta-secretase (BACE1). Semin Cell Dev Biol. 2009 Apr;20(2):175-82.

166    Willer CJ, ..., Heid IM,... Wichman HE,... Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet. 2009 Jan;41(1):25-34. Epub 2008 Dec 14.

165    Winkler C, Illig T, Koczwara K, Bonifacio E, Ziegler AG. HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes. J Clin Endocrinol Metab. 2009 Oct;94(10):4113-5. Epub 2009 Jul 21.

164    Wirth EK, Roth S, Blechschmidt C, Hölter SM, Becker L, Racz I, Zimmer A, Klopstock T, Gailus-Durner V, Fuchs H, Wurst W, Naumann T, Bräuer A, de Angelis MH, Köhrle J, Grüters A, Schweizer U. Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome. J Neurosci. 2009 Jul 29;29(30):9439-49.

163    Witt O, Deubzer HE, Lodrini M, Milde T, Oehme I.Targeting histone deacetylases in neuroblastoma. Curr Pharm Des. 2009;15(4):436-47.

162    Witt O, Deubzer HE, Milde T, Oehme I.HDAC family: What are the cancer relevant targets. Cancer Lett. 2009 May 8;277(1):8-21. Epub 2008 Sep 27.

161    Witt O, Lindemann R.HDAC inhibitors: magic bullets, dirty drugs or just another targeted therapy. Cancer Lett. 2009 Aug 8;280(2):123-4. Epub 2009 Mar 19

160    Yehuda R, Cai G, Golier JA, Sarapas C, Galea S, Ising M, Rein T, Schmeidler J, Müller-Myhsok B, Holsboer F, Buxbaum JD. Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks. Biol Psychiatry. 2009 Oct 1;66(7):708-11. Epub 2009 Apr 25. PubMed PMID: 19393990.

159    Youn BS, Bang SI, Klöting N, Park JW, Lee N, Oh JE, Pi KB, Lee TH, Ruschke K, Fasshauer M, Stumvoll M, Blüher M.Serum progranulin concentrations may be associated with macrophage infiltration into omental adipose tissue. Diabetes. 2009 Mar;58(3):627-36

158    Youns, M., Efferth, T., Reichling, J., Fellenberg, K., Bauer, A. & Hoheisel, J.D. (2009). Gene expression profiling identifies novel key players involved in the cytotoxic effect of Artesunate on pancreatic cancer cells. Biochem. Pharmacol. 2009; 78, 273-283.

157    Yu X, Wieczorek S, Franke A, Yin H, Pierer M, Sina C, Karlsen TH, Boberg KM, Bergquist A, Kunz M, Witte T, Gross WL, Epplen JT, Alarcón-Riquelme ME, Schreiber S, Ibrahim SM. Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases. Genes Immun. 2009 Sep;10(6):601-5. Epub 2009 Apr 23.

156    Zeilinger S, Pinto LA, Nockher WA, Depner M, Klopp N, Illig T, von Mutius E,Renz H, Kabesch M. The effect of BDNF gene variants on asthma in German children. Allergy. 2009 Dec;64(12):1790-4. PubMed PMID: 19895626.

155    Zhang, J. D. & Wiemann, S. KEGGgraph: a graph approach to KEGG PATHWAY in R and Bioconductor. Bioinformatics. 2009 Jun; 25(11):1470-1.

154    Zhang, JD., Duda, A., Schmidt, C., Irsigler, A., Wiemann, S. and Tschulena, U. (2009). Analyzing the Effect of Gene Knock-Down in Real-Time Using Roche?s xCELLigence System. Biochemica, 09/02.

153    Zhang, JD., Ernst, U., Irsigler, A., Wiemann, S. and Tschulena, U. (2009). qPCR Identification of Genes Involved in Apoptosis and Cell Cycle Regulation. Biochemica, 09/02.

152    Zhu J.Y., Pfuhl T., Motsch N., Barth S., Nicholls J., Grässer F. & Meister G. (2009) Identification of novel Epstein-Barr Virus microRNA genes from Nasopharyngeal Carcinomas. Journal of Virology, 83(7):3333-41.

151    Zimprich A, Schulte C, Reinthaler E, Haubenberger D, Balzar J, Lichtner P, El Tawil S, Edris S, Foki T, Pirker W, Katzenschlager R, Daniel G, Brucke T, Auff E, Gasser T. PARK11 gene (GIGYF2) variants Asn56Ser and Asn457Thr are not pathogenic for Parkinson's disease. Parkinsonism Relat Disord. 2009 Aug;15(7):532-4.

150    Zolles G, Wenzel D, Bildl W, Schulte U, Hofmann A, Mu?ller CS, Thumfart JO, Vlachos A, Deller T, Pfeifer A, Fleischmann BK,Roeper J, Fakler B, Klöcker N. Association with the auxiliary subunit PEX5R/Trip8b controls responsiveness of HCN channels tocAMP and adrenergic stimulation. Neuron. 2009 Jun 25; 62(6):814-25. doi:10.1016/j.neuron.2009.05.008

149    Zürner M, Schoch S. The mouse and human Liprin-alpha family of scaffolding proteins: genomic organization, expression profiling and regulation by alternative splicing. Genomics. 2009 Mar;93(3):243-53. Epub 2008 Dec 13.PMID: 19013515

148    Zweier C, de Jong EK, Zweier M, Orrico A, Ousager LB, Collins AL, Bijlsma EK, Oortveld MA, Ekici AB, Reis A, Schenck A, Rauch A. CNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in Drosophila. Am J Hum Genet. 2009 Nov;85(5):655-66. Epub 2009 Nov 5. PMID: 19896112.

2008


147    Abe K, Wechs S, Kalaydjiev S, Franz TJ, Busch DH, Fuchs H, Soewarto D, Behrendt H, Wagner S, Jakob T, Hrabé de Angelis M.: Novel lymphocyte-independent mechanisms to initiate inflammatory arthritis via bone marrow-derived cells of Ali18 mutant mice. Rheumatology 2008 47(3):292-300 doi:10.1093/rheumatology/kem358

146    Aguado C, Colón J, Ciruela F, Schlaudraff F, Cabañero MJ, Perry C, Watanabe M, Liss B, Wickman K, Luján R. Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum. J Neurochem. 2008 Apr;105(2):497-511. doi:10.1111/j.1471-4159.2007.05153.

145    Aigner, B., Rathkolb, B., Herbach, N., Hrabé de Angelis, M., Wanke, R., Wolf, E.: Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects. Am. J. Physiol. Endocrinol. Metab. 2008 294(2):E232-40 doi:10.1152/ajpendo.00592.2007

144    Andersson ER, Prakash N, Cajanek L, Minina E, Bryja V, Bryjova L, Yamaguchi TP, Hall AC, Wurst W, Arenas E. Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. PLoS ONE. 2008;3(10):e3517. Epub 2008 Oct 27

143    Balss J, Meyer J, Mueller W, Korshunov A, Hartmann C, von Deimling A; Analysis of the IDH1 codon 132 mutation in brain tumors. Acta Neuropathol. 2008 Dec;116(6):597-602

142    Becker AJ, Pitsch J, Sochivko D, Opitz T, Staniek M, Chen CC, Campbell KP, Schoch S, Yaari Y, Beck H.Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsy. J Neurosci.2008 Dec 3;28(49):13341-13353. doi:10.1523 PMID: 19052226

141    Bénard J, Raguénez G, Kauffmann A, Valent A, Ripoche H, Joulin V, Job B, Danglot G, Cantais S, Robert T, Terrier-Lacombe MJ, Chassevent A, Koscielny S, Fischer M, Berthold F, Lipinski M, Tursz T, Dessen P, Lazar V, Valteau-Couanet D.MYCN-non-amplified metastatic neuroblastoma with good prognosis and spontaneous regression: A molecular portrait of stage 4S. Mol Onc, 2008, 2(3): 261-271.

140    Bender A, Beckers J, Schneider I, Hölter SM, Haack T, Ruthsatz T, Vogt-Weisenhorn DM, Becker L, Genius J, Rujescu D, Irmler M, Mijalski T, Mader M, Quintanilla-Martinez L, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Wurst W, Schmidt J, Klopstock T.: Creatine improves health and survival of mice. Neurobiol Aging 2008 Sep;29(9):1404-11.  doi:10.1016/j.neurobiolaging.2007.03.001

139    Bender C, Froehlich H, Johannes M, Beissbarth T. Extending pathways with inferred regulatory interactions from microarray data and protein domain signatures. Proceedings of CAMDA, 2008.

138    Bode M, Irmler M, Friedenberger M, May C, Jung K, Stephan C, Meyer HE,Lach C, Hillert R, Krusche A, Beckers J, Marcus K, Schubert W. Interlocking transcriptomics, proteomics and toponomics technologies for brain tissue analysis in murine hippocampus. Proteomics 2008; 8(6):1170-8; doi 10.1002/pmic.200700742

137    Böhme M, Grallert H, Fischer A, Gieger C, Nitz I, Heid I, Kohl C, Wichmann HE, Illig T, Döring F; KORA Study Cohort, MTTP variants and body mass index, waist circumference and serum cholesterol level: Association analyses in 7582 participants of the KORA study cohort. Mol Genet Metab. 2008 Dec;95(4):229-32.

136    Bouatia-Naji N, De Graeve F, Brönner G, Lecoeur C, Vatin V, Durand E, LichtnerP, Nguyen TT, Heude B, Weill J, Lévy-Marchal C, Hebebrand J, Froguel P, Meyre D. INS VNTR is not associated with childhood obesity in 1,023 families: afamily-based study. Obesity (Silver Spring). 2008 Jun;16(6):1471-5. Epub 2008 Apr3. PubMed PMID: 18388898.

135    Bouvier M, Sharma CM, Mika F, Nierhaus KH, Vogel J. Small RNA binding to 5' mRNA coding region inhibits translational initiation. Mol Cell. 2008 Dec 26;32(6):827-37.

134    Buchholz M, Kestler H, Gress TM. Differential diagnosis of pancreatic tumors by molecular analysis of clinical specimens. Pancreatology. 2008;8(6):551-7.

133    Chen, Z., W. Huang, T. Dahme, W. Rottbauer, M.J. Ackerman, and X. Xu. (2008). Depletion of zebrafish essential and regulatory myosin light chains reduces cardiac function through distinct mechanisms. Cardiovasc Res 79:97-108.

132    Delic S, Streif S, Deussing JM, Weber P, Üffing M, Hölter SM, Wurst W, Kühn R. (2008) Genetic mouse models for behavioural analysis through transgenic RNAi technology. Genes Brain Behav 7(7):821-830

131    Deubzer HE, Ehemann V, Kulozik AE, Westermann F, Savelyeva L, Kopp-Schneider A, Riester D, Schwab M, Witt O. Anti-neuroblastoma activity of Helminthosporium carbonum (HC)-toxin is superior to that of other differentiating compounds in vitro. Cancer Lett. 2008 Jun 8;264(1):21-8. Epub 2008 Feb 8.

130    Deubzer HE, Ehemann V, Westermann F, Heinrich R, Mechtersheimer G, Kulozik AE, Schwab M, Witt O. Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells. Int J Cancer. 2008 Apr 15;122(8):1891-900.

129    Dölken L, Haas J. Small noncoding RNA: novel targets for antiviral therapy. Future Microbiol. 2008 Dec;3(6):585-8. PubMed PMID: 19072174.

128    Dölken L., Z. Ruzsics, B. Radle, C. C. Friedel, R. Zimmer, J. Mages, R. Hoffmann, P. Dickinson, T. Forster, P. Ghazal and U. H. Koszinowski (2008). "High-resolution gene expression profiling for simultaneous kinetic parameter analysis of RNA synthesis and decay." RNA 14(9): 1959-72.

127    Ehlermann P, Weichenhan D, Zehelein J, Steen H, Pribe R, Zeller R, Lehrke S, Zugck C, Ivandic BT, Katus HA. Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene. BMC Med Genet. 2008 Oct 28;9:95.

126    El-Gogo  S., B. Flach, C. Staib, G. Sutter and Adler, H.: In vivo attenuation of recombinant murine gammaherpesvirus 68 (MHV-68) is due to the expression and immunogenicity but not to the insertion of foreign sequences. Virology 380 (2008): 322-327

125    Engblom D, Bilbao-Leis A, Sanchis-Segura C, Dahan L, Perreau-Lenz S, Balland M, Rodriguez Parkitna J, Lujan R, Halbout B, Mameli M, Parlato R, Sprengel R, Lüscher C, Schütz G, Spanagel R. Glutamate receptors on dopamine neurons control the persistence of cocaine-seeking. Neuron. 2008; 59:497-508

124    Erhard, F., C. C. Friedel and R. Zimmer (2008). "FERN - a Java framework for stochastic simulation and evaluation of reaction networks." BMC Bioinformatics 9: 356.

123    Fanta S, Sonnenberg M, Skorta I, Duyster J, Miething C, Aulitzky WE, van der Kuip H. Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr-Abl-negative cells. Oncogene. 2008 Jul 17;27(31):4380-4.

122    Fassunke J, Majores M, Tresch A, Niehusmann P, Grote A, Schoch S, Becker AJ. Array analysis of epilepsyassociatedgangliogliomas reveals expression patterns related to aberrant development of neuronal precursors. Brain. 2008 Nov;131(Pt 11):3034-3050. doi:10.1093 PMID: 18819986

121    Fiebig A, Jepsen S, Loos BG, Scholz C, Schäfer C, Rühling A, Nothnagel M, Eickholz P, van der Velden U, Schenck K, Schreiber S, Grössner-Schreiber B. Polymorphisms in the interleukin-1 (IL1) gene cluster are not associated with aggressive periodontitis in a large Caucasian population. Genomics. 2008 Nov;92(5):309-15. Epub 2008 Sep 18.PMID: 18723088

120    Fischer A, Grallert H, Böhme M, Gieger C, Boomgaarden I, Heid IM, Wichmann HE, Döring F, Illig I. Association analysis between the PTGES2 R298H polymorphism and body mass index in 8079 participants of the KORA study cohort. Genetic Testing 2008

119    Fischer J, Emmerling C, Ruther U. On the history of Fto. Obes Facts. 2008;1(1):43-4.

118    Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G,Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM,Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL,Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH; IBSEN studygroup, Mathew CG, Schreiber S. Sequence variants in IL10, ARPC2 andmultiple other loci contribute to ulcerative colitis susceptibility. Nat Genet. 2008 Nov;40(11):1319-23. Epub 2008 Oct 5.

117    Froehlich H, Beissbarth T, Tresch A, Kostka D, Jacob J, Spang R, Markowetz F. Analyzing Gene Perturbation Screens With Nested Effects Models in R and Bioconductor. Bioinformatics, 2008, 24(21):2549-50.

116    Froehlich H, Fellmann M, Sueltmann H, Poustka A, Beissbarth T. Estimating Large Scale Signaling Networks through Nested Effects Models from Intervention Effects in Microarray Data. Bioinformatics, 2008, 24(22):2650-6

115    Frühwald MC, Witt O.The epigenetics of cancer in children. Klin Padiatr. 2008 Nov-Dec;220(6):333-41. Epub 2008 Oct 23.

114    Fuchs H., Lisse, T., Hans, W., Abe, K., Thiele, F., Gailus-Durner, V., Hrabé de Angelis, M.: Phenotypic characterization of mouse models for bone-related diseases in the German Mouse Clinic. J. Musculoskelet. Neuronal. Interact. 2008 Jan-Mar;8(1):13-4. PMID: 18398253

113    Gakhar-Koppole N, Hundeshagen P, Mandl C, Weyer SW, Alliquant B, Müller U, Ciccolini F (2008) Activity requires soluble amyloid precursor protein to promote neurite outgrowth in neural stem cell-derived neurons via activation of MAPK pathway. Eur J Neurosci 28:871-882

112    Geiger SK, Bär H, Ehlermann P, Wälde S, Rutschow D, Zeller R, Ivandic BT, Zentgraf H, Katus HA, Herrmann H, Weichenhan D. Incomplete nonsense-mediated decay of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardia. J Mol Med. 2008 Mar;86(3):281-9. Epub 2007 Nov 7.

111    Gross E, Busse B, Riemenschneider M, Neubauer S, Seck K, Klein HG, Kiechle M, Lordick F, Meindl A. Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS One. 2008;3(12):e4003. Epub 2008 Dec 23.

110    Gründemann J, Schlaudraff F, Haeckel O, Liss B. Elevated alpha-synuclein mRNA levels in individual UV-laser-microdissected dopaminergic substantia nigra neurons in idiopathic Parkinson's disease. Nucleic Acids Res. 2008 Apr;36(7):e38. doi:10.1093/nar/gkn084

109    Hahne F, Mehrle A, Arlt D, Poustka A, Wiemann S, Beissbarth T. Extending pathways based on gene list signatures using InterPro domains. BMC Bioinformatics 2008; 4;9(1):3

108    Hartl D, Irmler M, Romer I, Mader MT, Mao L, Zabel C, Hrabe de Angelis M,Beckers J, Klose J. Transcriptome and proteome analysis of early embryonic mouse brain development. Proteomics 2008;8(6):1257-65. doi 10.1002/pmic.200700724

107    Hartmann C, Wiestler O.D. Die neue WHO-Hirntumor-Klassifikation aus dem Jahr 2007, Brainstorm. 2008 Ausgabe 1: 22-25

106    Hasegawa T, Treis A, Patenge N, Fiesel FC, Springer W, Kahle PJ. Parkin protects against tyrosinase-mediated dopamine neurotoxicity by suppressing stress-activated protein kinase pathways. J Neurochem. 2008 Jun;105(5):1700-1715

105    Hassel, D., E.P. Scholz, N. Trano, O. Friedrich, S. Just, B. Meder, D.L. Weiss, E. Zitron, S. Marquart, B. Vogel, C.A. Karle, G. Seemann, M.C. Fishman, H.A. Katus, and W. Rottbauer. Deficient zebrafish ether-a-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants. Circulation. 117:866-875. 2008.

104    Hemminki K, Försti A, Bermejo JL. New cancer susceptibility loci: population and familial risks. Int J Cancer 2008;123:1726-29. doi 10.1002/ijc.23702

103    Hemminki K, Försti A, Bermelo JL. The ?common disease-common variant? hypothesis and familial risks. Plos ONE 2008;3:e2504 doi 10.1371/journal.pone.0002504

102    Hemminki K, Li X, Sundquist J, Sundquist K. Cancer risks in ulcerative colitis patients. Int J Cancer 2008;123:1417-21. doi 10.1002/ijc.23666

101    Hemminki K, Li X, Sundquist K, Sundquist J. Do inflammatory bowel disease and cancer share sus-ceptibility: A family study. Inflamm Bowel Dis 2008;14:1167-8. doi 10.1002/ibd.20427

100    Herder C, Rathmann W, Strassburger K, Finner H, Grallert H, Huth C, Meisinger C, Gieger C, Martin S, Giani G, Scherbaum WA, Wichmann HE, Illig T. Variants of the PPARG, IGF2BP2, CDKAL1, HHEX, and TCF7L2 genes confer risk of type 2 diabetes independently of BMI in the German KORA studies. Horm Metab Res. 2008 Oct;40(10):722-6. Epub 2008 Jul 2.

99    Hilfiker-Kleiner D, Knöll R. Disease-modifying mutations in familial hypertrophic cardiomyopathy: complexity from simplicity. Circulation. 2008 117(14):1775-1777.

98    Hoepken HH, Gispert S, Azizov M, Klinkenberg M, Ricciardi F, Kurz A, Morales-Gordo B, Bonin M, Riess O, Gasser T, Kögel D, Steinmetz H, Auburger G.Parkinson patient fibroblasts show increased alpha-synuclein expression. Exp Neurol. 2008 Aug;212(2):307-13.

97    Hofmann S, Franke A, Fischer A, Jacobs G, Nothnagel M, Gaede KI, Schürmann M, Müller-Quernheim J, Krawczak M, Rosenstiel P, Schreiber S. Genome-wide association study identifies ANXA11 as a new susceptibility locus for sarcoidosis. Nat Genet. 2008 Sep;40(9):1103-6. PMID: 19165924

96    Hölter SM, Dalke C, Kallnik M, Becker L, Horsch M, Schrewe A, Favor J, Klopstock T, Beckers J, Ivandic B, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Graw J, Wurst W.: 'Sighted C3H' mice - a tool for analysing the influence of vision on mouse behaviour? Front. Biosci. 2008;13:5810-23. doi:10.2741/3118

95    Holtkamp K, Bühren K, Ponath G, von Eiff C, Herpertz-Dahlmann B, Hebebrand J, Rothermundt M. Serum levels of S100B are decreased in chronic starvation andnormalize with weight gain. J Neural Transm. 2008 Jun;115(6):937-40. Epub 2008Apr 2. PubMed PMID: 18385926.

94    Horsch M., Schädler, S., Gailus-Durner, V., Fuchs, H., Meyer, H., Hrabé de Angelis, M., Beckers, J.: Systematic gene expression profiling of mouse model series reveals coexpressed genes. Proteomics 2008 Mar;8(6):1248-56 doi:10.1002/pmic.200700725

93    Houlston RS, Webb E, ... Hampe J, Buch S, Schafmayer C, ? Dunlop MG. Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet. 2008 Dec;40(12):1426-35

92    Hübner MP, Pasche B, Kalaydjiev S, Soboslay PT, Lengeling A, Schulz-Key H, Mitre E, Hoffmann WH. Microfilariae of the filarial nematode Litomosoides sigmodontis exacerbate the course of LPS-induced sepsis in mice. Infect. Immun. 2008 Apr;76(4):1668-1677. doi:10.1128/IAI.01042-07

91    Hubner N. The STAR Consortium, (2008) SNP and haplotype mapping for genetic analysis in the rat. Nat Genet. 40(5):560-566

90    Irmler M, Hartl D, Schmidt T, Schuchhardt J, Lach C, Meyer HE, Hrabe de Angelis M, Klose J, Beckers J. An approach to handling and interpretation of ambiguous data in transcriptome and proteome comparisons. Proteomics 2008;8(6):1165-9. doi10.1002/pmic.200700741

89    Kancha RK, von Bubnoff N, Miething C, Peschel C, Götze KS, Duyster J. Imatinib and leptomycin B are effective in overcoming imatinib-resistance due to Bcr-Abl amplification and clonal evolution but not due to Bcr-Abl kinase domain mutation. Haematologica. 2008 Nov;93(11):1718-22.

88    Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Ouwehand W, Price AL, Munroe P, Caulfield M, Drake T, Boerwinkle E, Reich D, Whitehead AS, Cappola TP, Samani NJ, Lusis AJ, Schadt E, Wilson JG, Koenig W et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies.

87    Kissling C, Retz W, Wiemann S, Coogan AN, Clement RM, Hunnerkopf R, Conner AC, Freitag CM, Rosler M, Thome J (2008) A polymorphism at the 3'-untranslated region of the CLOCK gene is associated with adult attention-deficit hyperactivity disorder. Am J Med Genet B Neuropsychiatr Genet 2008 147: 333-338.

86    Klein KM, Theisen F, Knake S, Oertel WH, Hebebrand J, Rosenow F, Hamer HM.Topiramate, nutrition and weight change: a prospective study. J Neurol Neurosurg Psychiatry. 2008 May;79(5):590-3. Epub 2007 Dec 12. PubMed PMID: 18077476.

85    Klöting N, Schleinitz D, Ruschke K, Berndt J, Fasshauer M, Tönjes A, Schön MR, Kovacs P, Stumvoll M, Blüher M. Inverse relationship between obesity and FTO gene expression in visceral adipose tissue in humans. Diabetologia. 2008 Apr;51(4):641-7.

84    Kohl T, Schmidt C, Wiemann S, Poustka A, Korf U (2008) Automated production of recombinant human proteins as resource for proteome research. Proteome Science 2008 6: 4.7.

83    Korf U, Derdak S, Tresch A, Henjes F, Schumacher S, Schmidt C, Hahn B, Lehmann WD, Poustka A, Beissbarth T, Klingmuller U (2008a) Quantitative protein microarrays for time-resolved measurements of protein phosphorylation. Proteomics 2008 8: 4603-4612.8.

82    Korf U, Henjes F, Schmidt C, Tresch A, Mannsperger H, Lobke C, Beissbarth T, Poustka A (2008b) Antibody microarrays as an experimental platform for the analysis of signal transduction networks. Adv Biochem Eng Biotechnol 2008 110: 153-175.9.

81    Kovacs P, Berndt J, Ruschke K, Klöting N, Schön MR, Körner A, Stumvoll M, Blüher M.TCF7L2 gene expression in human visceral and subcutaneous adipose tissue is differentially regulated but not associated with type 2 diabetes mellitus. Metabolism. 2008 Sep;57(9):1227-31.

80    Kruger R. (2008) LRRK2 in Parkinson?s disease ? drawing the curtain of penetrance. BMC Medicine 6: 30

79    Lammel S, Hetzel A, Häckel O, Jones I, Liss B, Roeper J. Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron. 2008 Mar 13;57(5):760-73.
doi:10.1016/j.neuron.2008.01.022

78    Lange, M., B. Kaynak, U.B. Forster, M. Tonjes, J.J. Fischer, C. Grimm, J. Schlesinger, S. Just, I. Dunkel, T. Krueger, S. Mebus, H. Lehrach, R. Lurz, J. Gobom, W. Rottbauer, S. Abdelilah-Seyfried, and S. Sperling. (2008). Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev 22:2370-2384.

77    Lao O, Lu TT, Nothnagel M, Junge O, Freitag-Wolf S, Caliebe A, Balascakova M, Bertranpetit J, Bindoff LA, Comas D, Holmlund G, Kouvatsi A, Macek M, Mollet I, Parson W, Palo J, Ploski R, Sajantila A, Tagliabracci A, Gether U, Werge T, Rivadeneira F, Hofman A, Uitterlinden AG, Gieger C, Wichmann HE, Rüther A, Schreiber S, Becker C, Nürnberg P, Nelson MR, Krawczak M, Kayser M. Correlation between genetic and geographic structure in Europe. Curr Biol. 2008 Aug 26;18(16):1241-8. Epub 2008 Aug 7.

76    Lehnart SE, Mongillo M, Bellinger A, Lindegger N, Chen BX, Hsueh W, Reiken S, Wronska A, Drew LJ, Ward CW, Lederer WJ, Kass RS, Morley G, Marks AR. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. J Clin Invest. 2008;118(6):2230-45

75    Linsel-Nitschke P, Götz A, Erdmann J, Braenne I, Braund P, Hengstenberg C,Stark K, Fischer M, Schreiber S, El Mokhtari NE, Schaefer A, Schrezenmeir J,Rubin D, Hinney A, Reinehr T, Roth C, Ortlepp J, Hanrath P, Hall AS, Mangino M,Lieb W, Lamina C, Heid IM, Doering A, Gieger C, Peters A, Meitinger T, WichmannHE, König IR, Ziegler A, Kronenberg F, Samani NJ, Schunkert H; Wellcome TrustCase Control Consortium (WTCCC); Cardiogenics Consortium. Lifelong reduction ofLDL-cholesterol related to a common variant in the LDL-receptor gene decreasesthe risk of coronary artery disease--a Mendelian Randomisation study. PLoS One.2008 Aug 0;3(8):e2986. Erratum in: PLoS ONE. 2008;3(9). doi:10.1371/annotation/9f64c41a-8cf6-40f2-8988-0d48b04dd8cb. Schrezenmeier, Jürgen[corrected to Schrezenmeir, Jürgen]. PubMed PMID: 18714375; PubMed Central PMCID:PMC2500189.

74    Liss B, Roeper J. Individual dopamine midbrain neurons: functional diversity and flexibility in health and disease. Brain Res Rev. 2008 Aug;58(2):314-21. doi:10.1016/j.brainresrev.2007.10.004

73    Lisse TS, Thiele F, Fuchs H, Hans W, Przemeck GK, Abe K, Rathkolb B, Quintanilla-Martinez L, Hoelzlwimmer G, Helfrich M, Wolf E, Ralston SH, Hrabé de Angelis M.: ER Stress-Mediated Apoptosis in a New Mouse Model of Osteogenesis imperfecta. PLoS Genet. 2008 4(2):e7 doi:10.1371/journal.pgen.0040007

72    Lobke C, Laible M, Rappl C, Ruschhaupt M, Sahin O, Arlt D, Wiemann S, Poustka A, Sultmann H, Korf U (2008) Contact spotting of protein microarrays coupled with spike-in of normalizer protein permits time-resolved analysis of ERBB receptor signaling. Proteomics 2008 8: 1586-1594.10.

71    Loos RJ, Lindgren CM, Li S, Wheeler E, Zhao JH, Prokopenko I, Inouye M, Freathy RM, Attwood AP, Beckmann JS, Berndt SI; Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial, Jacobs KB, Chanock SJ, Hayes RB, Bergmann S, Bennett AJ, Bingham SA, Bochud M, Brown M, Cauchi S, Connell JM, Cooper C, Smith GD, Day I, Dina C, De S, Dermitzakis ET, Doney AS, Elliott KS, Elliott P, Evans DM, Sadaf Farooqi I, Froguel P, Ghori J, Groves CJ, Gwilliam R, Hadley D, Hall AS, Hattersley AT, Hebebrand J, Heid IM; KORA, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Herrera B, Hinney A, Hunt SE, Jarvelin MR, Johnson T, Jolley JD, Karpe F, Keniry A, Khaw KT, Luben RN, Mangino M, Marchini J, McArdle WL, McGinnis R, Meyre D, Munroe PB, Morris AD, Ness AR, Neville MJ, Nica AC, Ong KK, O'Rahilly S, Owen KR, Palmer CN, Papadakis K, Potter S, Pouta A, Qi L; Nurses' Health Study, Randall JC, Rayner NW, Ring SM, Sandhu MS, Scherag A, Sims MA, Song K, Soranzo N, Speliotes EK; Diabetes Genetics Initiative, Syddall HE, Teichmann SA, Timpson NJ, Tobias JH, Uda M; SardiNIA Study, Vogel CI, Wallace C, Waterworth DM, Weedon MN; Wellcome Trust Case Control Consortium, Willer CJ; FUSION, Wraight, Yuan X, Zeggini E, Hirschhorn JN, Strachan DP, Ouwehand WH, Caulfield MJ, Samani NJ, Frayling TM, Vollenweider P, Waeber G, Mooser V, Deloukas P, McCarthy MI, Wareham NJ, Barroso I, Jacobs KB, Chanock SJ, Hayes RB, Lamina C, Gieger C, Illig T, Meitinger T, Wichmann HE, Kraft P, Hankinson SE, Hunter DJ, Hu FB, Lyon HN, Voight BF, Ridderstrale M, Groop L, Scheet P, Sanna S, Abecasis GR, Albai G, Nagaraja R, Schlessinger D, Jackson AU, Tuomilehto J, Collins FS, Boehnke M, Mohlke KL. Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet. 2008; 40:768-75.

70    Maier H., Lengger, C., Simic, B., Fuchs, H., Gailus-Durner, V., Hrabé de Angelis, M.: MausDB: an open source application for phenotype data and mouse colony management in large-scale mouse phenotyping projects. BMC Bioinformatics 2008 26;9:169 doi: 10.1186/1471-2105-9-169

69    Mathivanan, S. et al. (2008). Human Proteinpedia enables sharing of human protein data. Nat Biotechnol 26, 164-7.

68    McGowan KA, Li JZ, Park CY, Beaudry V, Tabor HK, Sabnis AJ, Zhang W, Fuchs H, Hrabé de Angelis M, Myers RM, Attardi LD, Barsh GS.: Ribosomal mutations cause p53-mediated dark skin and pleiotropic effects. Nat. Genet. 2008 Aug;40(8):963-70. Epub 2008 Jul 20; doi:10.1038/ng.188

67    Meder, B., H.A. Katus, and W. Rottbauer. (2008). Right into the heart of microRNA-133a. Genes Dev 22:3227-3231.

66    Melum E, Buch S, Schafmayer C, Kalthoff H, Tepel J, Schreiber S, Karlsen TH, Hampe J. Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma. Intl. J. Cancer 2008, 123(1):241-2.

65    Menke A, Lucae S, Kloiber S, Horstmann S, Bettecken T, Uhr M, Ripke S, IsingM, Müller-Myhsok B, Holsboer F, Binder EB. Genetic markers within glutamatereceptors associated with antidepressant treatment-emergent suicidal ideation. Am J Psychiatry. 2008 Jul;165(7):917-8.

64    Mercader JM, Saus E, Agüera Z, Bayés M, Boni C, Carreras A, Cellini E, de Cid R, Dierssen M, Escaramís G, Fernández-Aranda F, Forcano L, Gallego X, GonzálezJR, Gorwood P, Hebebrand J, Hinney A, Nacmias B, Puig A, Ribasés M, Ricca V, RomoL, Sorbi S, Versini A, Gratacòs M, Estivill X. Association of NTRK3 and itsinteraction with NGF suggest an altered cross-regulation of the neurotrophinsignaling pathway in eating disorders. Hum Mol Genet. 2008 May 1;17(9):1234-44.Epub 2008 Jan 18. PubMed PMID: 18203754.

63    Metzeler KH, Hummel M, Bloomfield CD, Spiekermann K, Braess J, Sauerland M-C, Heinecke A, Radmacher M, Marcucci G, Whitman SP, Maharry K, Paschka P, Larson RA, Berdel WE, Büchner T, Wörmann B, Mansmann U, Hiddemann W, Bohlander SK*, Buske C*. An 86 probe set gene expression signature predicts survival in cytogenetically normal acute myeloid leukemia. Blood. 2008;112(10):4193-201. (*Both authors contributed equally.)

62    Michaelis M, Bliss J, Arnold SC, Hinsch N, Rothweiler F, Deubzer HE, Witt O, Langer K, Doerr HW, Wels WS, Cinatl J Jr. Cisplatin-resistant neuroblastoma cells express enhanced levels of epidermal growth factor receptor (EGFR) and are sensitive to treatment with EGFR-specific toxins. Clin Cancer Res. 2008 Oct 15;14(20):6531-7.

61    Michaud J, Simpson KM, Escher R, Buchet-Poyau K, Beissbarth T, Carmichael C, Ritschie ME, Schutz F, Cannon P, Liu M, Shen X, Ito Y, Raskind WH, Horwitz MS, Sato M, Urner DR, Speed TP, Kavallaris M, Smyth GK, Scott HS. Integrative analysis of RUNX1 downstream pathways and target genes. BMC Genomics, 2008, 9:363

60    Monti J; Fischer J; Paskas S; Heinig M; Schulz H; Gösele C; Heuser A; Fischer R; Schmidt C; Schirdewan A; Gross V; Hummel O; Maatz H; Patone G; Saar K; Vingron M; Weldon SM; Lindpaintner K; Hammock BD; Rohde K; Dietz R; Cook SA; Schunck WH; Luft FC; Hubner N. Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. Nature Genetics 40 (5): 529-537 (2008).

59    Müller T., A. Hinney, C. Roth, J. Hebebrand,  F. Schreiner, A. Scherag, T. Nugyen, T. Reinehr: Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents. BMC Medical Genetics 2008, 9:85

58    Müller TD, Reichwald K, Brönner G, Kirschner J, Nguyen TT, Scherag A, Herzog W, Herpertz-Dahlmann B, Lichtner P, Meitinger T, Platzer M, Schäfer H, Hebebrand J, Hinney A. Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa. Child Adolesc Psychiatry Ment Health. 2008; 2:33.

57    Nair RP, Ruether A, Stuart PE, Jenisch S, Tejasvi T, Hiremagalore R, Schreiber S, Kabelitz D, Lim HW, Voorhees JJ, Christophers E, Elder JT, Weichenthal M. Polymorphisms of the IL12B and IL23R genes are associated with psoriasis. J Invest Dermatol 2008;128(7):1653-61. PMID: 18219280

56    Nicolaou P, Knöll R, Haghighi K, Fan GC, Dorn GW, 2nd, Hasenfub G, Kranias EG. Human mutation in the anti-apoptotic heat shock protein 20 abrogates its cardioprotective effects. The Journal of biological chemistry. 2008 283(48):33465-33471.

55    Nothnagel M, Lu TT, Krawczak M. Hypotheses in genome-wide association scans. Eur J Hum Genet. 2008 Oct;16(10):1174-5; author reply 1175. Epub 2008 May 14. PMID: 18478034

54    Nyholt DR, LaForge KS, Kallela M, Alakurtti K, Anttila V, Färkkilä M, Hämaläinen E, Kaprio J, Kaunisto MA, Heath AC, Montgomery GW, Göbel H, Todt U, ..., Brand J, Freilinger T, Pfaffenrath V, Straube A, Ballinger DG, Zhan Y, Daly MJ, Cox DR, Dichgans M, van den Maagdenberg AM, Kubisch C, Martin NG, Wessman M, Peltonen L, Palotie A. A high-density association screen of 155 ion transport genes for involvement with common migraine. Hum Mol Genet. 2008 Nov 1;17(21):3318-31. PMID: 18676988

53    Oberthuer A, Kaderali L, Kahlert Y, Hero B, Westermann F, Berthold F, Brors B, Eils R, Fischer M.Sub-classification and individual survival time prediction from gene-expression data of neuroblastoma patients using CASPAR. Clin Cancer Res, 2008, 14(20): 6590-6601.

52    O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer C, Howie B, Leung HT, Hartmann AM, Möller HJ, Morris DW, Shi Y, Feng G, Hoffmann P, Propping P,  Vasilescu C, Rieschel M, Zammit S, Schumacher J, Quinn EM, Schulze TG, Williams NM,  Giegling I, Iwata N, Ikeda M, Darvasi A, Shifman S, He L, Molecular Genetics of Schizophrenia Collaboration, Cichon S, Nöthen MM, Gill M, Corvin A, Rujescu D, Kirov G, Owen MJ. (2008) Identification of novel schizophrenia loci by genome-wide association and follow-up. Nature Genetics. Sep;40(9):1053-5. (impact factor: 30,3)

51    Pandey P, Brors B, Srivastava PK, Bott A, Boehn SN, Groene HJ, Gretz N.Microarray-based approach identifies microRNAs and their target functionalpatterns in polycystic kidney disease. BMC Genomics. 2008 Dec 23;9:624.

50    Pepperkok, R. and Wiemann, S. (2008). Integrating systems biology with clinical research. Genome Biol 9, 314.

49    Petretto E, Sarwar R, Grieve I, Lu H, Kumaran MK, Muckett PJ, Mangion J, Schroen B, Benson M, Punjabi PP, Prasad SK, Pennell DJ, Kiesewetter C, Tasheva ES, Corpuz LM, Webb MD, Conrad GW, Kurtz TW, Kren V, Fischer J, Hubner N, Pinto YM, Pravenec M, Aitman TJ, Cook SA. (2008) Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass. Nat Genet. 40(5):546-52.

48    Petropoulos K, Arseni N, Schessl C, Stadler CR, Rawat VP, Deshpande AJ, Heilmeier B, Hiddemann W, Quintanilla-Martinez L, Bohlander SK, Feuring-Buske M, Buske C. A novel role for Lef-1, a central transcription mediator of Wnt signaling in leukemogenesis. J Exp Med. 2008 Mar; 205(3):515-522. doi 10.1084/jem.20071875

47    Pfister S, Janzarik WG, Remke M, Ernst A, Werft W, Becker N, Toedt G, Wittmann A, Kratz C, Olbrich H, Ahmadi R, Thieme B, Joos S, Radlwimmer B, Kulozik A, Pietsch T, Herold-Mende C, Gnekow A, Reifenberger G, Korshunov A, Scheurlen W, Omran H, Lichter P. BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas. J Clin Invest. 2008 May;118(5):1739-49.

46    Pittman AM, Webb E, Carvajal-Carmona L, Howarth K, Di-Bernardo M, Broderick P, Spain S, Walther A, Price A, Sullivan K, Twiss P, Fielding S, Rowan A, Jaeger E, Vijayakrishnan J, Chandler I, Penegar S, Qureshi M, Lubbe S, Domingo E, Kemp Z, Barclay E, Wood W, Martin L, Gorman M, Thomas H, Peto J, Bishop T, Gray R, Maher ER, Lucassen A, Kerr D, Evans GR; The CORGI Consortium, van Wezel T, Morreau H, Wijnen JT, Hopper JL, Southey MC, Giles GG, Severi G, Castellví-Bel S, Ruiz-Ponte C, Carracedo A, Castells A; The EPICOLON Consortium, Försti A, Hemminki K, Vodicka P, Naccarati A, Lipton L, Ho JW, Cheng KK, Sham PC, Luk J, Agúndez JA, Ladero JM, de la Hoya M, Caldés T, Niittymäki I, Tuupanen S, Karhu A, Aaltonen L, Cazier JB, Tomlinson IP, Houlston RS. Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colo-rectal cancer. Hum Mol Genet 2008;17:3720-7. doi 10.1093/hmg/ddn267

45    Poser I, Sarov M, Hutchins JR, Hériché JK, Toyoda Y, Pozniakovsky A, Weigl D, Nitzsche A, Hegemann B, Bird AW, Pelletier L, Kittler R, Hua S, Naumann R, Augsburg M, Sykora MM, Hofemeister H, Zhang Y, Nasmyth K, White KP, Dietzel S, Mechtler K, Durbin R, Stewart AF, Peters JM, Buchholz F, Hyman AA.BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.Nat Methods. 2008 May;5(5):409-15. Epub 2008 Apr 6.

44    Postel R, Vakeel P, Topczewski J, Knöll R, Bakkers J. Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex. Dev Biol. 2008 318(1):92-101.

43    Pravenec M, Churchill PC, Churchill MC, Viklicky O, Kazdova L, Aitman TJ, Petretto E, Hubner N, Wallace CA, Zimdahl H, Zidek V, Landa V, Dunbar J, Bidani A, Griffin K, Qi N, Maxova M, Kren V, Mlejnek P, Wang J, Kurtz TW. (2008) Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nat Genet. 40(8):952-4

42    Prudencio M, Rodrigues CD, Hannus M, Martin C, Real E, Gonçalves LA, Carret C, Dorkin R, Röhl I, Jahn-Hoffmann K, Luty AJ, Sauerwein R, Echeverri CJ, Mota MM. Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection. 2008. PLoS Pathog 4(11): e1000201.

41    Puk O., Dalke, C., Hrabé de Angelis, M., Graw, J.: Variation of the response to the optokinetic drum among various strains of mice. Front. Biosci. 2008 May 1;13:6269-75 PMID: 18508659

40    Racz I, Bilkei-Gorzo A, Markert A, Stamer F, Gothert M, Zimmer A (2008) Anandamide effects on 5-HT(3) receptors in vivo. Eur J Pharmacol 2008; 596:98-101. doi:10.1016/j.ejphar.2008.08.012

39    Racz I, Nadal X, Alferink J, Banos JE, Rehnelt J, Martin M, Pintado B, Gutierrez-Adan A, Sanguino E, Manzanares J, Zimmer A, Maldonado R (2008) Crucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain. J Neurosci 2008; 28:12125-12135. DOI:10.1523/JNEUROSCI.3400-08.2008

38    Racz I, Schurmann B, Karpushova A, Reuter M, Cichon S, Montag C, Furst R, Schutz C, Franke PE, Strohmaier J, Wienker TF, Terenius L, Osby U, Gunnar A, Maier W, Bilkei-Gorzo A, Nothen M, Zimmer A (2008) The opioid peptides enkephalin and beta-endorphin in alcohol dependence. Biol Psychiatry 2008; 64: 989-997.

37    Racz I., X. Nadal, J. Alferink, J. E. Baños, J. Rehnelt, M. Martín, B. Pintado, A. Gutierrez-Adan, E. Sanguino, N. Bellora, J. Manzanares, A. Zimmer, R. Maldonado, Interferon-? is a critical modulator of CB2 cannabinoid receptor signaling during neuropathic pain. J of Neuroscience (2008) 28(46): 12136-45 DOI:10.1523/JNEUROSCI.3402-08.2008

36    Radke S, Chander H, Schäfer P, Meiss G, Krüger R, Schulz JB, Germain D. (2008) Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi. J Biol Chem 283: 12681-12685

35    Rawat VP, Thoene S, Naidu VM, Arseni N, Heilmeier B, Metzeler K, Petropoulos K, Deshpande A, Quintanilla-Martinez L, Bohlander SK, Speikermann K, Hiddemannn W, Feuring-Buske M, Buske C. Overexpression of CDX2 perturbs HOX gene expression in murine progenitors deoending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia. Blood. 2008 Jan; 111(1):309-319. doi 10.1182/blood.200704085407

34    Reinehr T, Friedel S, Mueller TD, Toschke AM, Hebebrand J, Hinney A. Evidence for an influence of TCF7L2 polymorphism rs7903146 on insulin resistance andsensitivity indices in overweight children and adolescents during a lifestyleintervention. Int J Obes (Lond). 2008 Oct;32(10):1521-4. Epub 2008 Sep 2. PubMed PMID: 18762805.

33    Reinehr T, Hinney A., TT. Nguyen, J. Hebebrand: Evidence for an influence of a polymorphism near the INSIG2 on weight loss during a lifestyle intervention in obese children and adolescents. Diabetes 2008;57 623-626

32    Roth CL, Hinney A, Reinehr T, Schreiner F, Nguyen TT, Müller T, Scholl C, Woelfle J, Karpushova A, Schäfer H, Nöthen MM, Hebebrand J. TCF7L2 polymorphism rs7903146 and predisposition for type 2 diabetes mellitus in obese children. Horm Metab Res. 2008 Oct;40(10):713-7. Epub 2008 Jun 10.

31    Royeck, M., Remy, S., Reitze, M., Yaari, Y., and Beck, H. (2008) The role of axonal Nav1.6 in action potential initiation of CA1 neurons. J. Neurophysiol. 2008, 100: 2361-80.

30    Sansone, S.A. et al. (2008). The first RSBI (ISA-TAB) workshop: "can a simple format work for complex studies?" Omics 12, 143-9.

29    Sauermann M, Sahin Ö, Sültmann H, Hahne F, Blaszkiewicz S, Majety M, Füzesi L, Poustka A, Wiemann S, Arlt D. Reduced expression of the Vacuole membrane protein 1 (Vmp1) affects the invasion capacity of tumor cells. Oncogene 2008; 27:1320-6.

28    Schmidt S, Gawlik V, Hölter SM, Augustin R, Scheepers A, Behrens M, Wurst W, Gailus-Durner V, Fuchs H, Hrabé de Angelis M, Kluge R, Joost HG, Schürmann A.: Deletion of glucose transporter GLUT8 in mice increases locomotor activity. Behav. Genet. 2008 Jul;38(4):396-406. doi:10.1007/s10519-008-9208-1

27    Schnütgen F, Hansen J, De-Zolt S, Horn C, Lutz M, Floss T, Wurst W, Noppinger PR, von Melchner H. Enhanced gene trapping in mouse embryonic stem cells. Nucleic Acids Res. 2008 Nov;36(20):e133. Epub 2008 Sep 23.PMID: 18812397 [PubMed - indexed for MEDLINE]

26    Schubert W, Bode M, Hillert R, Krusche A, Friedenberger M. Toponomics and neurotoponomics: a new way to medical systems biology. Expert Rev Proteomics. 2008 Apr;5(2):361-9. Review. doi:10.1586/14789450.5.2.361

25    Schubert W, Friedenberger M, Bode M, Krusche A, Hillert R. Functional architecture of the cell nucleus: towards comprehensive toponome reference maps of apoptosis. Biochim Biophys Acta. 2008 Nov;1783(11):2080-8. Epub 2008 Jul 31. doi:10.1016/j.bbamcr.2008.07.019

24    Schuchhardt J, Glintschert A, Hartl D, Irmler M, Beckers J, Stephan C, Marcus K, Klose J, Meyer HE, Malik A. BrainProfileDB - a platform for integration of functional genomics data. Proteomics 2008;8(6):1162-4. doi 10.1002/pmic.200700743

23    Schulte JH, Kirfel J, Lim S, Schramm A, Friedrichs N, Deubzer HE, Witt O, Eggert A, Buettner R.Transcription factor AP2alpha (TFAP2a) regulates differentiation and proliferation of neuroblastoma cells. Cancer Lett. 2008 Nov 18;271(1):56-63. Epub 2008 Jul 11.

22    Schumann G, Johann M, Frank J, Preuss U, Dahmen N, Laucht M, Rietschel M,Rujescu D,
Lourdusamy A, Clarke TK, Krause K, Dyer A, Depner M, Wellek S,Treutlein J, Szegedi A, Giegling I, Cichon S, Blomeyer D, Heinz A, Heath S,Lathrop M, Wodarz N, Soyka M, Spanagel R, Mann K. Systematic analysis ofglutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior. Arch Gen Psychiatry. 2008 Jul;65(7):826-38. PubMed PMID:18606955.

21    Schunkert H, Götz A, Braund P, McGinnis R, Tregouet DA, Mangino M, Linsel-Nitschke P, Cambien F, Hengstenberg C, Stark K, Blankenberg S, Tiret L, Ducimetiere P, Keniry A, Ghori MJ, Schreiber S, El Mokhtari NE, Hall AS, Dixon RJ, Goodall AH, Liptau H, Pollard H, Schwarz DF, Hothorn LA, Wichmann HE, König IR, Fischer M, Meisinger C, Ouwehand W, Deloukas P, Thompson JR, Erdmann J, Ziegler A, Samani NJ; Cardiogenics Consortium. Repeated replication and a prospective meta-analysis of the association between chromosome 9p21.3 and coronary artery disease.

20    Söker T, Dalke C, Puk O, Floss T, Becker L, Bolle I, Favor J, Hans W, Hölter SM, Horsch M, Kallnik M, Kling E, Moerth C, Schrewe A, Stigloher C, Topp S, Gailus-Durner V, Naton B, Beckers J, Fuchs H, Ivandic B, Klopstock T, Schulz H, Wolf E, Wurst W, Bally-Cuif L, Hrabé de Angelis M, Graw J.: Pleiotropic effects in Eya3 knockout mice. BMC Dev. Biol. 2008 Dec 22;8:118; doi: 10.1186/1471-213X-8-118.

19    Stefansson H, Rujescu D, Cichon S, Pietiläinen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal T, Haraldsson M, Magnusdottir BB, Giegling I, Möller HJ, Hartmann A, Shianna KV, Ge D, Need AC, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Paunio T, Toulopoulou T, Bramon E, Di Forti M, Murray R, Ruggeri M, Vassos E, Tosato S, Walshe M, Li T, Vasilescu C, Mühleisen TW, Wang AG, Ullum H, Djurovic S, Melle I, Olesen J, Kiemeney LA, Franke B, Kahn RS, Linszen DH, van Os J, Wiersma D, Bruggeman R, Cahn W, de Haan L, Krabbendam L, Myin-Germeys I, Sabatti C, Freimer NB, Gulcher JR, Thorsteinsdottir U, Kong A, Andreassen OA, Ophoff RA, Georgi A, Rietschel M, Werge T, Petursson H, Goldstein DB, Nöthen MM, Peltonen L, Collier DA, St Clair D, Stefansson K. (2008) Large recurrent microdeletions associated with schizophrenia. Nature. Sep 11 2008 ;455(7210):232-6 (impact factor: 31,4)

18    Taylor, C.F. et al. (2008). Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project. Nat Biotechnol 26, 889-96.

17    Teichler S, Schlenk RF, Strauch K, Hagner NM, Ritter M, Neubauer A. Expression of the nuclear oncogene Ski in patients with acute myeloid leukemia treated with all-trans retinoic acid. Haematologica. 2008 Jul; 93(7):1105-7.

16    Tenesa A, Farrington SM, ? Schafmayer C, Tepel J, Schreiber S, Völzke H, Schmidt CO, Hampe J, ? Campbell H, Dunlop MG. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nature Genetics 2008, 40(5):631-7

15    Thum, T., C. Gross, J. Fiedler, T. Fischer, S. Kissler, M. Bussen, P. Galuppo, S. Just, W. Rottbauer, S. Frantz, M. Castoldi, J. Soutschek, V. Koteliansky, A. Rosenwald, M.A. Basson, J.D. Licht, J.T. Pena, S.H. Rouhanifard, M.U. Muckenthaler, T. Tuschl, G.R. Martin, J. Bauersachs, and S. Engelhardt. (2008). MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456:980-984.

14    Toischer K, Kögler H, Tenderich G, Grebe C, Seidler T, N. N, Jung K, Knöll R, Körfer R, Hasenfuss G. Elevated Afterload, Neuroendocrine Stimulation, and Human Heart Failure Increase BNP Levels and Inhibit Preload-Dependent SERCA Upregulation. Circulation Heart Failure. 2008; 1:265-271.

13    Tomlinson IP, Webb E, Carvajal-Carmona L, Broderick P, Howarth K, Pittman AM, Spain S, Lubbe S, Walther A, Sullivan K, Jaeger E, Fielding S, Rowan A, Vijayakrishnan J, Domingo E, Chandler I, Kemp Z, Qureshi M, Farrington SM, Tenesa A, Prendergast JG, Barnetson RA, Penegar S, Barclay E, Wood W, Martin L, Gorman M, Thomas H, Peto J, Bishop DT, Gray R, Maher ER, Lucassen A, Kerr D, Evans DG; The CORGI Consortium, Schafmayer C, Buch S, Völzke H, Hampe J, Schreiber S, John U, Koessler T, Pharoah P, van Wezel T, Morreau H, Wijnen JT, Hopper JL, Southey MC, Giles GG, Severi G, Castellví-Bel S, Ruiz-Ponte C, Carracedo A, Castells A; The EPICOLON Consortium, Försti A, Hemminki K, Vodicka P, Naccarati A, Lipton L, Ho JW, Cheng KK, Sham PC, Luk J, Agúndez JA, Ladero JM, de la Hoya M, Caldés T, Niittymäki I, Tuupanene S, Karhu A, Aaltonen L, Cazier JB, Campbell H, Dunlop MG, Houlston RS. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 2008;40:623-30.

12    Tribl F, Meyer HE, Marcus K. Analysis of organelles within the nervous system: impact on brain and organelle functions. Expert Rev Proteomics. 2008 Apr;5(2):333-51. Review. PMID: 18466061

11    Tricarico D, Mele A, Liss B, Ashcroft FM, Lundquist AL, Desai RR, George AL Jr, Conte Camerino D. Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats. Neuromuscul Disord. 2008 Jan; 18(1):74-80. doi:10.1016/j.nmd.2007.07.009

10    Tuin I, Voss U, Kessler K, Krakow K, Hilker R, Morales B, Steinmetz H, Auburger G.Sleep quality in a family with hereditary parkinsonism (PARK6). Sleep Med. 2008 Aug;9(6):684-8.

9    Tulupova E, Kumar R, Hanova M, Slyskova J, Pardini B, Polakova V, Naccarati A, Vodickova L, No-votny J, Halamkova J, Hemminki K, Vodicka P. Do polymorphisms and haplotypes of mismatch re-pair genes modulate risk of sporadic colorectal cancer? Mutat Res 2008;648:40-5. doi 10.1016/j.mrfmmm.2008.09.005

8    Van Laere S, Beissbarth T, Auwera VI, Eynden VG, Trinh XB, Elst H, Hummelen P, Dam P, Marck E, Vermeulen P, Dirix L. Relapse-free survival in breast cancer patients is associated with a gene expression signature characteristic for inflammatory breast cancer. Clin Cancer Res, 2008, 14(22):7452-60.

7    Veenstra T, Marcus K. Multidimensional advancement of neuroproteomics. Expert Rev Proteomics. 2008 Apr;5(2):149-51. PMID: 18466109

6    Walitza S, Scherag A, Renner TJ, Hinney A, Remschmidt H, Herpertz-Dahlmann B, Schulz E, Schäfer H, Lange KW, Wewetzer C, Gerlach M. Transmission disequilibrium studies in early onset of obsessive-compulsive disorder for polymorphisms in genes of the dopaminergic system. J Neural Transm. 2008; 115:1071-8.

5    Wegener D, Deubzer HE, Oehme I, Milde T, Hildmann C, Schwienhorst A, Witt O.HKI 46F08, a novel potent histone deacetylase inhibitor, exhibits antitumoral activity against embryonic childhood cancer cells. Anticancer Drugs. 2008 Oct;19(9):849-57.

4    Weidinger S, O'Sullivan M, Illig T, Baurecht H, Depner M, Rodriguez E, Ruether A, Klopp N, Vogelberg C, Weiland SK, McLean WH, von Mutius E, Irvine AD, Kabesch M. Filaggrin mutations, atopic eczema, hay fever, and asthma in children. J Allergy Clin Immunol. 2008 May;121(5):1203-1209.e1. Epub 2008 Apr 8.

3    Wermter AK, Scherag A, Meyre D, Reichwald K, Durand E, Nguyen TT, Koberwitz K, Lichtner P, Meitinger T, Schäfer H, Hinney A, Froguel P, Hebebrand J, Brönner G. Preferential reciprocal transfer of paternal/maternal DLK1 alleles to obese children: first evidence of polar overdominance in humans. Eur J Hum Genet. 2008; 16:1126-34.

2    Westermann F, Muth D, Benner A, Bauer T, Henrich KO, Oberthuer A, Brors B, Beissbarth T, Vandesompele J, Pattyn F, Hero B, König R, Fischer M, Schwab M.Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblasotmas. Genome Biol, 2008, 9(10): R150.

1    Yamasaki C, Murakami K, Fujii Y, Sato Y, Harada E, Takeda J, Taniya T, Sakate R, Kikugawa S, Shimada M, Tanino M, Koyanagi KO, Barrero RA, Gough C, Chun HW, Habara T, Hanaoka H, Hayakawa Y, Hilton PB, Kaneko Y, Kanno M, Kawahara Y, Kawamura T, Matsuya A, Nagata N, Nishikata K, Noda AO, Nurimoto S, Saichi N, Sakai H, Sanbonmatsu R, Shiba R, Suzuki M, Takabayashi K, Takahashi A, Tamura T, Tanaka M, Tanaka S, Todokoro F, Yamaguchi K, Yamamoto N, Okido T, Mashima J, Hashizume A, Jin L, Lee KB, Lin YC, Nozaki A, Sakai K, Tada M, Miyazaki S, Makino T, Ohyanagi H, Osato N, Tanaka N, Suzuki Y, Ikeo K, Saitou N, Sugawara H, O'Donovan C, Kulikova T, Whitfield E, Halligan B, Shimoyama M, Twigger S, Yura K, Kimura K, Yasuda T, Nishikawa T, Akiyama Y, Motono C, Mukai Y, Nagasaki H, Suwa M, Horton P, Kikuno R, Ohara O, Lancet D, Eveno E, Graudens E, Imbeaud S, Debily MA, Hayashizaki Y, Amid C, Han M, Osanger A, Endo T, Thomas MA, Hirakawa M, Makalowski W, Nakao M, Kim NS, Yoo HS, De Souza SJ, Bonaldo Mde F, Niimura Y, Kuryshev V, Schupp I, Wiemann S, Bellgard M, Shionyu M, Jia L, Thierry-Mieg D, Thierry-Mieg J, Wagner L, Zhang Q, Go M, Minoshima S, Ohtsubo M, Hanada K, Tonellato P, Isogai T, Zhang J, Lenhard B, Kim S, Chen Z, Hinz U, Estreicher A, Nakai K, Makalowska I, Hide W, Tiffin N, Wilming L, Chakraborty R, Soares MB, Chiusano ML, Suzuki Y, Auffray C, Yamaguchi-Kabata Y, Itoh T, Hishiki T, Fukuchi S, Nishikawa K, Sugano S, Nomura N, Tateno Y, Imanishi T, Gojobori T (2008) The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts. Nucleic Acids Res 2008 36: D793-799.


Buchbeiträge 2008 bis 2013


2013

116 Charlet K, Beck A, Heinz A Drug Addiction (Chapter III.7) In: MRI in Psychiatry. Shenton M, and Mulert C (Editors). Springer-Verlag. Heidelberg, Germany. (in press).

115 Charlet K, Beck A, Heinz A The Dopamine System in Mediating Alcohol Effects in Humans. In: Current Topics in Behavioral Neuroscience (CTBN) - Behavioral Neurobiology of Alcohol Addiction. Spanagel R, and Sommer WH (Editors). Springer-Verlag. Heidelberg, Germany. Curr Top Behav Neurosci. 13:461-488.

114 Dubitzky W., Wolkenhauer O., Cho K., Yokota H. (eds) Gieseler A. Synaptic proteins. In Encyclopedia of Systems Biology Springer Science+Business Media: Berlin, Heidelberg (in press).

113 Dubitzky W., Wolkenhauer O., Cho K., Yokota H. (eds) Gieseler A. Synaptic toponome. In Encyclopedia of Systems Biology Springer Science+Business Media: Berlin, Heidelberg (in press)

112 Dubitzky W., Wolkenhauer O., Cho K., Yokota H. (eds) Hillert R. Toponome Analysis. In Encyclopedia of Systems Biology Springer Science+Business Media: Berlin, Heidelberg (in press)

111 Dubitzky W., Wolkenhauer O., Cho K., Yokota H. (eds) Hillert R. Combinatorial Molecular Phenotype. In Encyclopedia of Systems Biology Springer Science+Business Media: Berlin, Heidelberg (in press).

110 Dubitzky W., Wolkenhauer O., Cho K., Yokota H. (eds) Krusche A. TIS robot. In Encyclopedia of Systems Biology Springer Science+Business Media: Berlin, Heidelberg (in press).

109 Dubitzky W., Wolkenhauer O., Cho K., Yokota H. (eds) Schubert W. Toponomics. In Encyclopedia of Systems Biology Springer Science+Business Media: Berlin, Heidelberg (in press).

108 Hinney A, Volckmar AL, Knoll N. Melanocortin-4 receptor in energy homeostasis and obesity pathogenesis. Prog Mol Biol Transl Sci. 2013;114:147-91. doi: 10.1016/B978-0-12-386933-3.00005-4. PubMed PMID: 23317785.

107 Müller, U. and Wild, K. Structure and Function of the APP Intracellular Domain in Health and Disease. InTech, Understanding Alzheimer's Disease, ISBN 978-953-51-1009-5.

106 Petri S. & Meister G. siRNA design principles and off-target effects. Methods Mol Biol., 986:59-71.

105 Rodriguez E, Weidinger S (2013). Genetics of atopic dermatitis. In: Bieber T. Advances in Atopic Dermatitis. Future Science Group E-Book Series, in press.

104 Sprengel, R. Ionotropic Glutamate Receptors. Neuroscience in the 21st Century - From Basic to Clinical. D. W. Pfaff. Ney York, Springer. 1: 59-80.

2012

103 Antel J, Hebebrand J. Weight-reducing side effects of the antiepileptic agentstopiramate and zonisamide. Handb Exp Pharmacol. 2012;209:433-66. PubMed PMID: 22249827.

102 Artati A, Prehn C, Möller G, Adamski J: Assay Tools for Metabolomics. In: Genetics meets metabolomics: from experiment to systems biology. In K. Suhre (ed.), Genetics Meets Metabolomics: from Experiment to Systems Biology, Springer Science+Business Media, pp. 13-38 (2012).

101 Beck A, Grace AA, Heinz A Reward Processing (Chapter 5). In: Neuroimaging in the addictions. Adinoff B, and Stein EA, editors. Wiley-Blackwell.

100 Brosius, J. RNAissance. In: From Nucleic Acids Sequences to Molecular Medicine, RNA Technologies (V.A. Erdmann, J. Barciszewski, eds.). Springer-Verlag Berlin Heidelberg, pp. 1-18.

99 Burbulla L, Krüger R. Loss of mortalin function in Parkinson's disease ? supporting the mitochondrial pathway of neurodegeneration. In: Kaul SC and Wadhwa R (eds) Mortalin ? Life, Stress, Death. Springer Verlag, New York, pp 159-178.

98 Fuchs H, Neschen S, Rozman J, Rathkolb B, Wagner S, Adler T, Afonso L, Aguilar-Pimentel JA, Becker L, Bohla A, Calzada-Wack J, Cohrs C, Franko A, Garrett L, Glasl L, Götz A, Hagn M, Hans W, Hölter SM, Horsch M, Kahle M, Kistler M, Klein-Rodewald T, Lengger C, Ludwig T, Maier H, Marschall S, Miklich K, Möller G, Naton B, Neff F, Prehn C, Puk O, Rácz I, Räß M, Scheerer M, Schiller E, Schöfl F, Schrewe A, Steinkamp R, Stöger C, Treise I, Willerhäuser M, Wolff-Muscate A, Zeh R, Adamski J, Beckers J, Bekeredjian R, Busch DH, Esposito I, Favor J, Graw J, Katus H, Klopstock T, Ollert M, Schulz H, Stöger T, Wurst W, Yildirim AÖ, Zimmer A, Wolf E, Klingenspor M, Gailus-Durner V, Hrabé de Angelis M. (2012) . Mouse genetics and metabolic mouse phenotyping In: Genetics meets metabolomics: from experiment to systems biology. Ed. by Karsten Suhre. Springer Heidelberg-New York, in press.

97 Grimm C, Adjaye J. Analysis of the methylome of human embryonic stem cells employing methylated DNA immunoprecipitation coupled to next-generation sequencing. In Methods Mol Biol 873, Human Embryonic Stem Cell Handbook. Turksen K. editor. Springer Science and Business Media. 2012:281-95.

96 Harder, N., Batra, R., Gogolin, S., Diessl, N., Eils, R., Westermann, F., König, R., Rohr, K. Cell Tracking for Automatic Migration and Proliferation Analysis in High-Throughput Screens. Bildverarbeitung für die Medizin 2012 (BVM 2012), Informatik aktuell, Editor(s): Handels H; Ehrhardt J; Deserno TM; Meinzer H-P; Tolxdorff T. Springer-Verlag, 2012.

95 Hoheisel, J.D. Funktionelle Genom- und Proteomforschung in der Krebsforschung. Bioelektronische Diagnose- und Therapiesysteme; m3: microelectronics meets medicine (Wolf, B., eds.) Shaker Verlag, Aachen, 57-60.

94 Kluge R, Scherneck S, Schürmann A, Joost HG. Pathophysiology and genetics of obesity and diabetes in the New Zealand obese mouse: a model of the human metabolic syndrome. Methods Mol Biol. 933, 59-73 (2012).

93 May C., Brosseron F., Chartowski P., Meyer H.E., Marcus K. Differential Proteome Analysis using 2D-DIGE Methods Mol Biol., In: Quantitaive Methods in Proteomics, Humana Press, Editor: Katrin Marcus, 893:75-82.

92 May C., Brosseron F., Pfeiffer K., Meyer H.E., Marcus K. Proteome Analysis with classical 2D PAGE. Methods Mol Biol., In: Quantitaive Methods in Proteomics, Humana Press, Editor: Katrin Marcus, 893:37-46.

91 Rabiller, M., D. Rauh Chemische Biologie ? innovative chemische Ansätze zum Studium biologischer Fragestellungen, Bioanalytik, (F. Lottspeich, J. Engels) Spektrum Akademischer Verlag, 2012, 3., aktualisierte und erweiterte Auflage.

90 Schubert W. Toponomanalyse. In: Lottspeich F., Engels J.W. (Eds.) 3nd edn. Springer Spektrum, Berlin, Heidelberg: 1140-1151. 2012.

89 Spanagel R. Pharmakologische Aspekte des Alkohols. Alkohol u. Tabak, Thieme Verlag.

88 Spanagel R, Bachteler D. Tiermodelle zur Alkoholabhängigkeit. Alkohol u. Tabak, Thieme Verlag.

87 Wabitsch M, Tews D, Denzer C, Moss A, Lennerz B, von Schnurbein J, Fischer-Posovszky P: Obesity and weight regulation Yearbook in Pediatric Endocrinology 2012Herausgeber: Carel, Hochberg.

86 Willershäuser M, Ehrhardt N, Elvert R, Wirth EK, Schweizer U, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Rozman J, Klingenspor M. Systematic Screening forMutant Mouse Lines with Defects in Body Temperature Regulation. In: Ruf T et al. (eds) Living in a Seasonal World. Springer-Verlag Berlin Heidelberg, in press.

85 Worseck JM, Grossmann A, Weimann M, Hegele A, Stelzl U. A stringent yeast two-hybrid matrix screening approach for protein-protein interaction discovery. Methods Mol Biol. 2012;812:63-87.

2011

84 Becker KF, Schott C. Protein extraction from formalin-fixed, paraffin-embedded Tissues. Stanta, G; editors(s). Guidelines for Molecular Analysis in Archive Tissues. Berlin Heidelberg: Springer; 2011. p. pp245-pp248. (ISBN: 978-3-642-17889-4)

83 Beitzinger M. & Meister G. Experimental Identification of MicroRNA Targets by Immunoprecipitation of Argonaute Protein Complexes. Methods Mol Biol, 732: 153-167.

82 Berg D, Malinowsky K, Reischauer B, Wolff C, Becker KF. Use of formalin-fixed and paraffin-embedded tissues for diagnosis and therapy in routine clinical settings. Methods Mol Biol. 2011;785:109-22.

81 Brase JC, Mannsperger H, Sültmann H, Korf U. Antibody-mediated signal amplification for reverse phase protein array-based protein quantification. Methods Mol Biol 785: 55-64, 2011

80 Charlet K, Beck A, Heinz A. The Dopamine System in Mediating Alcohol Effects in Humans. Current Topics in Behavioral Neuroscience (CTBN) 2011 Jul 7. [Epub ahead of print] - Behavioral Neurobiology of Alcohol Addiction. Spanagel R, and Sommer WH, editors. Springer-Verlag. Heidelberg, Germany. [Epub ahead of print]

79 Faoro V, Becker KF, Stanta G. One dimensional Sodium dodecyl sulfate (SDS) polyarcylamide gel electrophoresis. Stanta, G; editors(s). Guidelines for Molecular Analysis in Archive Tissues. Berlin Heidelberg: Springer; 2011. p. pp261-pp264. (ISBN: 978-3-642-17889-4)

78 Faoro V, Becker KF, Stanta G. Visualization of proteins. Stanta, G; editors(s). Guidelines for Molecular Analysis in Archive Tissues. Berlin Heidelberg: Springer; 2011. p. pp265-pp270. (ISBN: 978-3-642-17889-4)

77 Faoro V, Becker KF, Stanta G. Western blotting. Stanta, G; editors(s). Guidelines for Molecular Analysis in Archive Tissues. Berlin Heidelberg: Springer; 2011. p. pp271-pp274. (ISBN: 978-3-642-17889-4)

76 Gailus-Durner V, Naton B, Adler T, Afonso L, Aguilar-Pimentel J, Becker L, Calzada-Wack J, Cohrs C, da Silva-Buttkus P, Hans W, Horsch M, Kahle M, Lengger C, Ludwig T, Maier H, Micklich K, Möller G, Neff F, Neschen S, Prehn C, Rathkolb B, Rozman J, Schiller E, Schrewe A, Scheerer M, Schöfer F, Steinkamp R, Stöger C, Thiele F, Tost M, Treise I, Willershäuser M, Zeh R, Adamski J, Bekeredjian R, Beckers J, Esposito I, Höfler H, Katus H, Klingenspor M, Klopstock T, Ollert M, Wolf E, Busch DH, Fuchs H, and M Hrabé de Angelis. The German Mouse Clinic – Running an Open Access Platform. Mouse as a Model Organism, Chapter 2. 11pp, Springer Science+Business Media B.V. DOI 10.1007/978-94-007-0750-4_2 C. Brakebusch, T. Pihlajaniemi (eds.),

75 Gründemann J, Schlaudraff F, Liss B. UV-laser microdissection and mRNA expression analysis of individual neurons from postmortem Parkinson's disease brains. Methods Mol Biol. 2011;755:363-
74. doi:10.1007/978-1-61779-163-5

74 Grünewald A, Klein C. Parkin-associated Parkinson's disease. Parkinson?s Disease, Chapter 14, 2nd Edition, R. Pfeifer (Hrsg.), im Druck.

73 Hamacher M, Gröttrup B, Eisenacher M, Marcus K, Park YM, Meyer HE, Kwon KH, Stephan C. Inter-lab proteomics: data mining in collaborative projects on the basis of the HUPO brain proteome project's pilot studies. Methods Mol Biol. 2011;696:235-46. PMID: 21063951

72 Henjes F, Götschel F, Jöcker A, Korf U. Quantitative analysis of phosphoproteins using microspot immunoassays. Methods Mol Biol. 785, 191-201.PIMD: 21901601

71 Hölter SM, Glasl L. High throughput mouse phenotyping. Animal models of movement disorders: Vol. I, Neuromethods, vol. 61, Humana Press DOI:10.1007/978-1-61779-298-4_7, Dunnett SB, Lane E (eds)

70 Kabesch M, Weidinger S. Clinical implications of genetic findings. In: Atopic dermatitis in childhood and adolescence. Kiess W, Branski D, editors. Karger, Basel 2011

69 Lange, B.M.H.; Schweiger, R.M.; Lehrach, H. Global molecular and cellular measurement technologies. book chapter in: Cesario A and Marcus F B (editors) Springer Dordrecht Heidelberg London New York, Cancer Systems Biology: Bioinformatics and Medicine: Research and Clinical Applications, (2011).

68 Maljevic S, Lerche H. Epileptogenesis in idiopathic epilepsy. The Causes of Epilepsy. Common and Uncommon Causes in Adults and Children. Edited by: Simon D. Shorvon, Frederick Andermann, RenzoGuerrini. Cambridge University Press, Cambridge. 2011. ISBN 978-1-4051-8383-3

67 Mannsperger HM, Uhlmann S, Korf U, Sahin Ö. Utilization of RNAi to validate antibodies for reverse phase protein arrays (2011). Methods Mol Biol. 785, 45-54. PIMD: 21901592

66 May C, Brosseron F, Chartowski P, Schumbrutzki C, Schoenebeck B, Marcus K. Instruments and Methods in Proteomics. Methods Mol Biol. 2011;696:3-26. PMID: 21063938

65 Pechlivanis S, Scherag A, Pütter C, Moebus S. Metabochip ? a next generation genotyping platform. In: Biometrische Aspekte der Genomanalyse V - Schwerpunkt: Next Generation Sequencing Data Analysis. Hemmelmann C, Ahnert P, Foraita R, Großhennig A, Scherag A, Biebler KE (Ed.), pages 47-55. Shaker, Aachen, 2011

64 Rabiller, M., J.R. Simard, D. Rauh. Dissecting Phosphorylation Networks: The Use of Analogue-Sensitive Kinases and More Specific Kinase Inhibitors as Tools. Protein Kinases as Drug Targets (B. Klebl, G. Müller and M. Hamacher) Wiley VCH, 2011.

63 Ralph Rapley, Stuart Harbron, Mohamed Saiel Saeed, Alhamdani, Jörg D. Hoheisel. Antibody microarrays in proteome profiling. Molecular Analysis and Genome Discovery. Wiley, 219-243.

62 Schanda J, Henschler R, Grez M, Wichmann C. Analysis of leukemogenic gene products in hematopoietic progenitor cells. In: Acute Leukemia: Basic Mechanisms of Leukemogenesis. Koschmieder S & Krug U, ed. (InTech Verlag) p339-362.

61 Scherag A. Editorial. In: Biometrische Aspekte der Genomanalyse V - Schwerpunkt: Next Generation Sequencing Data Analysis. Hemmelmann C, Ahnert P, Foraita R, Großhennig A, Scherag A, Biebler KE (Ed.), pages 1-4. Shaker, Aachen, 2011.

60 Schott C, Becker KF. Reverse phase protein microarrays. Stanta, G; editors(s). Guidelines for Molecular Analysis in Archive Tissues. Berlin Heidelberg: Springer; 2011. p. pp279-pp284. (ISBN: 978-3-642-17889-4)

59 Schröder, C., Alhamdani, M.S.S., Fellenberg, K., Bauer, A., Jacob, A. & Hoheisel, J.D. Robust protein profiling with complex antibody microarrays in a dual-colour mode. Protein Microarrays ? Meth. Mol. Biol. (Korf, U., ed.), Humana/Springer, 203-221.

58 Sonntag J, Mannsperger HM, Jöcker A, Korf U. Microspot immunoassay-based analysis of plasma protein profiles for biomarker discovery strategies. Methods Mol Biol. 2011;785:237-45.

57 Stoehr J. & Meister G. In Vitro RISC Cleavage Assay. Methods Mol Biol, 725: 77-90.

56 Thormann A, Rasche A. Functional Context Network of T2DM. Medical Complications of Type 2 Diabetes. C. Croniger, editor. In Tech Publishing. 2011:213-230

55 Wabitsch M, Tews D, Keuper M, Posovszky C, Denzer C, Kotnik P, Moss A, von Schnurbein J, Fischer-Posovszky P. Obesity and weight regulation. Yearbook in Pediatric Endocrinology 2011Herausgeber: Carel, Hochberg

54 Weidinger S, Irvine AD (2011). Genetics of atopic dermatitis. In: Irvine AD, Oranje A, Prose N. Textbook of Pediatric Dermatology (Third Edition). Blackwell Science, London

53 Weidinger S, Irvine AD. Genetics of atopic eczema. In: Text Book of Pediatric Dermatology, X. Edition. Irvine AD, Hoeger PH, Yan AC, editors. Wiley-Blackwell, Oxford, 2011.

52 Wolff C, Schott C, Malinowsky K, Berg D, Becker KF. Producing reverse phase protein microarrays from formalin-fixed tissues. Methods Mol Biol. 2011;785:123-40.

2010

51 Alberts R and K. Schughart. High throughput gene expression analysis and the identification of expression QTLs. Chapter in: Gene Discovery for Disease Models: John Wiley & Sons, Inc., Hoboken, New Jersey, U.S.A., in press.

50 Beck A, Grace AA, Heinz A. Reward Processing. In Neuroimaging in the addictions. Adinoff B, and Stein EA, editors. Wiley-Blackwell. (in press)

49 Brase JC, Mannsperger H, Sültmann H and Korf U. Antibody-mediated signal amplification for RPPA-based protein quantification. In Methods in Molecular Biology, U Korf (volume editor) and J Walker (series editor). Humana Press/Springer, New York. in press.

48 Charlet K, Beck A, Heinz A. The Dopamine System in Mediating Alcohol Effects in Humans. In: Current Topics in Behavioral Neuroscience (CTBN) - Behavioral Neurobiology of Alcohol Addiction. Spanagel R, and Sommer W.H., editors. Springer-Verlag. Heidelberg, Germany.

47 Daskalaki A, Wierling C, Herwig R. Computational tools and resources for systems biology approaches in cancer. In Computational Biology - Issues and Applications in Oncology, Series: Applied Bioinformatics and Biostatistics in Cancer Research. T. Pham, editor. Springer, New York. 2009:227-242

46 De-Zolt, S., Ruiz, P., Altschmied, J., von Melchner, H., and Schnütgen, F. Gene Trap Vectors and Mutagenesis. Meth. Mol. Biol. 2009, 530, 1-19

45 Dräger, A, Schröder, A and Zell, A: Systems Biology for Signaling Networks Automating mathematical modeling of biochemical reaction networks, pages 159-205. Springer-Verlag, 2010, 2 , July 2010.

44 Duitama, J., Huebsch, T., McEwen, G., Suk, E., and Hoehe, M. R. 2010. ReFHap: a reliable and fast algorithm for single individual haplotyping. In Proceedings of the First ACM international Conference on Bioinformatics and Computational Biology (Niagara Falls, New York, August 02 - 04, 2010). BCB '10. ACM, New York, NY, 160-169.

43 Emig D, Kacprowski T, Albrecht M. Measuring and analyzing tissue specificity of human genes and protein complexes. In Proceedings of the 7th International Workshop on Computational Systems Biology (WCSB), Tampere International Center for Signal Processing (TICSP series), Tampere University of Technology, Tampere, Finland, ISBN 978-952-15-2384-7. 2010 Jun;51:27-30.

42 Erhard, F., C. C. Friedel and R. Zimmer (2009). FERN - Stochastic Simulation and Evaluation of Reaction Networks. in Systems Biology for Signaling Networks. S. Choi (Ed.), Springer.

41 Gailus-Durner V, Fuchs H, Adler T, Aguilar Pimentel A, Becker L, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Ferwagner B, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Mörth C, Moßbrugger I, Naton B, Prehn C, Puk O, Rathkolb B, Rozman J, Schrewe A, Thiele F, Adamski J, Aigner B, Behrendt H, Busch DH, Favor J, Graw J, Heldmaier G, Ivandic B, Katus H, Klingenspor M, Klopstock T, Ollert M, Quintanilla-Martinez L, Schulz H, Wolf E, Wurst W, Hrabé de Angelis M (2009) Systemic first-line phenotyping. In: Kühn R, Wurst W (eds). Gene Knockout Protocols: Second Edition, Humana Press; Methods Mol Biol vol. 530, pp. 463-509.

40 Heinz A, Beck A, Mir J, Grüsser SM, Grace AA & Wrase J. Alcohol craving and relapse prediction ? imaging studies. In Advances in the Neuroscience of Addiction. Koob GF, and Kuhn C, editors. Taylor & Francis Group.

39 Henjes F, Götschel F, Jöcker A, Korf U. Quantitative analysis of protein phosphorylation using microspot immunoassays. In Methods in Molecular Biology, U Korf (volume editor) and J Walker (series editor). Humana Press/Springer, New York. Submitted.

38 Hölter SM, Cryan JF. Phenotyping of Behavioural Characteristics. In: Encyclopedia of Psychopharmacology, Ian P. Stolerman (ed.), Springer-Verlag (2010); DOI 10.1007/978-3-540-68706-1

37 Hubner, Nina C. and Mann, Matthias: Extracting gene function from protein-protein interactions using Quantitative BAC InteraCtomics (QUBIC)?. Invited manuscript for Methods for extracting function from mammalian genomes?, Elsevier Methods, Dec 2010, doi:10.1016/j.ymeth.2010.12.016

36 Ildiko Racz, Daniela Mauer, Andras Bilkei-Gorzo. Alkohol, Tabak und Folgeerkrankungen Singer, Batra, Mann, Georg Thieme Verlag KG. geplante Erscheinung 2010 September Kapitel 3.4 Tiermodelle zur Nikotinabhängigkeit

35 Kabsch M, Weidinger S. Clinical implications of genetic findings. In: Atopic dermatitis in childhood and adolescence. Kiess W, Branski D, editors. Karger, Basel 2010

34 Lange BM, Schweiger MR, Lehrach H. Cancer Systems Biology, Bioinformatics and Medicine: Research and Clinical Applications. F.Marcus and A.Cesario, editors. Springer 2010

33 Lange BM, Schweiger, R.M.; Lehrach, H. Global molecular and cellular measurement technologies.book chapter in: Cancer Systems Biology, Bioinformatics and Medicine: Research and Clinical Applications A. Cesario; F.B. Marcus (editors); Springer Verlag, (2010).

32 Lerche H, Petrou S. Genetic animal models (chapter 39). In: Atlas of epilepsies. Editor: Panayiotopoulos CP, 2010, pp 295-306

31 Liss B, Roeper J. Ion channels and regulation of dopamine neuron activity. In The Dopamine Handbook; A. Bjorklund, S. Dunnett,L. Iversen, S. Iversen, editors. Oxford University Press/UK, Oxford. 2009:118-138

30 Malzkorn B, Wolter M, Reifenberger G. MicroRNA: Biogenesis, regulation, and role in primary brain tumors. In: Therapeutic RNAs in brain tumors. Erdman V, Reifenberger G, Barciszewski J, editors. Springer Verlag, Heidelberg, 2009.

29 Mannsperger H, Uhlmann S, Sahin Ö and Korf U.