Publikationen

2013

43 Lascorz J, Bevier M, V Schönfels W, Kalthoff H, Aselmann H, Beckmann J, Egberts J, Buch S, Becker T, Schreiber S, Hampe J, Hemminki K, Schafmayer C, Försti A.  Association study identifying polymorphisms in CD47 and other extracellular matrix pathway genes as putative prognostic markers for colorectal cancer.  Int J Colorectal Dis 2013;28(2):173-81. doi: 10.1007/s00384-012-1541-4.

2012

42 Ammerpohl, O., Pratschke, J., Schafmayer, C., Haake, A., Faber, W., von Kampen, O., Brosch, M., Sipos, B., von Schönfels, W., Balschun, K., Röcken, C., Arlt, A., Schniewind, B., Grauholm, J., Kalthoff, H., Neuhaus, P., Stickel, F., Schreiber, S., Becker, T., Siebert, R. und Hampe, J.  Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma. Int J Cancer 130, 1319-1328. Epub 2011-07-21.
 
41 Huhn S, Bevier M, Rudolph A, Pardini B, Naccarati A, Hein R, Hoffmeister M, Vodickova L, Novotny J, Brenner H, Chang-Claude J, Vodicka P, Hemminki K, Försti A.  Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.  BMC Med Genet 2012;13:94. doi: 10.1186/1471-2350-13-94.

40 Huhn S, Pardini B, Naccarati A, Vodicka P, Hemminki K, Försti A.  Ancestral susceptibility to colorectal cancer.  Mutagenesis 2012:27(2)197-204. doi: 10.1093/mutage/ger061.

39 Lascorz J, Bevier M, Schönfels WV, Kalthoff H, Aselmann H, Beckmann J, Egberts J, Buch S, Becker T, Schreiber S, Hampe J, Hemminki K, Försti A, Schafmayer C.  Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer. BMC Med Genet 2012;13:31. doi: 10.1186/1471-2350-13-31.

2011

38 Castro, F.A., Försti, A., Buch, S., Kalthoff, H., Krauss, C., Bauer, M., Egberts, J., Schniewind, B., Broering, D.C., Schreiber, S., Schmitt, M., Hampe, J., Hemminki, K. und Schafmayer, C. TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer. Eur J Cancer 47, 1203-1210.

37 Herrmann A, Haake A, Ammerpohl O, Martin-Guerrero I, Szafranski K, Stemshorn K, Nothnagel M, Kotsopoulos SK, Richter J, Warner J, Olson J, Link DR, Schreiber S, Krawczak M, Platzer M, Nürnberg P, Siebert R, Hampe J. Pipeline for large-scale microdroplet bisulfite PCR-based sequencing allows the tracking of hepitype evolution in tumors. PLoS One. 2011;6(7):e21332. Epub 2011 Jul 5.

36 Nothnagel M, Herrmann A, Wolf A, Schreiber S, Platzer M, Siebert R, Krawczak M, Hampe J. Technology-specific error signatures in the 1000 Genomes Project data. Hum Genet. 2011 Oct;130(4):505-16. Epub 2011 Feb 23.

35 Nothnagel M, Wolf A, Herrmann A, Szafranski K, Vater I, Brosch M, Huse K, Siebert R, Platzer M, Hampe J, Krawczak M. Statistical inference of allelic imbalance from transcriptome data. Hum Mutat. 2011 Jan;32(1):98-106.

34 Rudolph A, Sainz J, Hein R, Hoffmeister M, Frank B, Försti A, Brenner H, Hemminki K, Chang-Claude J.Modification of menopausal hormone therapy associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes. Endocr Relat Cancer 2011;18:371-384. doi 10.4103/1477-3163.78268

33 Sainz J, Rudolph A, Hein R, Hoffmeister M, Buch S, von Schönfels W, Hampe J, Schafmayer C, Völzke H, Frank B, Brenner H, Försti A, Hemminki K, Chang-Claude J. Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk. Endocr Relat Cancer. 2011 Mar 9;18(2):265-76. Print 2011 Apr.

2010

32 Ammerpohl O., Pratschke J., Schafmayer C.,  Faber W., van Kampen O., Brosch M., Sipos B., Balschun K., Röcken C., Arlt A., Schniewind B., Grauholm J., Kalthoff H., Neuhaus P., Stickel F., Schreiber S., Bröring D., Siebert R., Hampe J. Distinct DNA methylation patterns in cirrhotic liver and hepatocellular carcinoma, Hepatology 2010

31 Buch S, Schafmayer C, Völzke H, Seeger M, Miquel JF, Sookoian SC, Egberts JH, Arlt A, Pirola CJ, Lerch MM, John U, Franke A, von Kampen O, Brosch M, Nothnagel M, Kratzer W, Boehm BO, Bröring DC, Schreiber S, Krawczak M, Hampe J. Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition. Gastroenterology. 2010 Dec;139(6):1942-1951.e2. Epub 2010 Sep 15.

30 Buechling T, Bartscherer K, Ohkawara B, Chaudhary V, Spirohn K, Niehrs C, Boutros M. Wnt/Frizzled signaling requires dPRR, the Drosophila homolog of the prorenin receptor. Curr Biol. 2010 Jul 27;20(14):1263-8.

29 Försti A, Li X, Wagner K, Tavelin B, Enquist K, Palmqvist R, Altieri A, Hallmans G, Hemminki K, Lenner P. Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression. Genes Chromosomes Cancer. 2010 Mar;49(3):270-81. doi 10.1002/gcc.20738

28 Frank B, Hoffmeister M, Klopp N, Illig T, Chang-Claude J, Brenner H. Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk. Int J Cancer 2010 Dec;127(12):2822-30.doi 10.1002/ijc.25299

27 Frank B, Hoffmeister M, Klopp N, Illig T, Chang-Claude J, Brenner H. Colorectal cancer and polymorphisms in DNA repair genes WRN, RMI1 and BLM. Carcinogenesis. 2010 Mar;31(3):442-5. doi 10.1093/carcin/bgp293

26 Frank B, Hoffmeister M, Klopp N, Illig T, Chang-Claude J, Brenner H. Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancer. Carcinogenesis. 2010 Aug;31(8):1381-6. doi 10.1093/carcin/bgq082

25 Hemminki K, Li X, Sundquist K, Sundquist J. Familial association of inflammatory bowel diseases with other autoimmune and related diseases. Am J Gastroenterol. 2010 Jan;105(1):139-47. doi 10.1038/ajg.2009.496

24 Kramer M, Backhaus O, Rosenstiel P, Horn D, Klopocki E, Birkenmeier G, Schreiber S, Platzer M, Hampe J, Huse K. Analysis of relative gene dosage and expression differences of the paralogs RABL2A and RABL2B by Pyrosequencing. Gene. 2010;455(1-2):1-7.

23 Lascorz J, Försti A, Chen B, Buch S, Steinke V, Rahner N, Holinski-Feder E, Morak M, Schackert HK, Görgens H, Schulmann K, Goecke T, Kloor M, Engel C, Büttner R, Kunkel N, Weires M, Hoffmeister M, Pardini B, Naccarati A, Vodickova L, Novotny J, Schreiber S, Krawczak M, Bröring CD, Völzke H, Schafmayer C, Vodicka P, Chang-Claude J, Brenner H, Burwinkel B, Propping P, Hampe J, Hemminki K. Chromosomal damage in peripheral blood lymphocytes of newly diagnosed cancer patients and healthy controls. Carcinogenesis 31(7): 1238-1241

22 Lascorz J, Försti A, Chen B, Buch S, Steinke V, Rahner N, Holinski-Feder E, Morak M, Schackert HK, Görgens H, Schulmann K, Goecke T, Kloor M, Engel C, Büttner R, Kunkel N, Weires M, Hoffmeister M, Pardini B, Naccarati A, Vodickova L, Novotny J, Schreiber S, Krawczak M, Bröring CD, Völzke H, Schafmayer C, Vodicka P, Chang-Claude J, Brenner H, Burwinkel B, Propping P, Hampe J, Hemminki K. Genome-wide association study for colorectal cancer identifies risk polymorphisms in German familial cases and implicates MAPK signalling pathways in disease susceptibility. Carcinogenesis 2010 Sep;31:1612-9. doi 10.1093/carcin/bgq146

21 Pelz O, Gilsdorf M, Boutros M. web cellHTS: A web-application for the analysis of high-throughput screening data. BMC Bioinformatics. 2010 Apr 12;11(1):185.

20 Sinha R, Thorsten Lenser, Niels Jahn, Ulrike Gausmann, Swetlana Friedel, Karol Szafranski, Klaus Huse, Philip Rosenstiel, Jochen Hampe, Stefan Schuster, Michael Hiller, Rolf Backofen and Matthias Platzer. TassDB2 - A comprehensive database of subtle alternative splicing events  BMC Bioinformatics 2010, 11:216doi:10.1186/1471-2105-11-216

19 Taudien S, Groth M, Huse K, Petzold A, Szafranski K, Hampe J, Rosenstiel P, Schreiber S, Platzer M. Haplotyping and copy number estimation of the highly polymorphic human beta-defensin locus on 8p23 by 454 amplicon sequencing. BMC Genomics. 2010 Apr 19;11(1):252

18 Tomlinson IP, Dunlop M, Campbell H, Zanke B, Gallinger S, Hudson T, Koessler T, Pharoah PD, Niittymäki I, Tuupanen S, Aaltonen LA, Hemminki K, Lindblom A, Försti A, Sieber O, Lipton L, van Wezel T, Morreau H, Wijnen JT, Devilee P, Matsuda K, Nakamura Y, Castellví-Bel S, Ruiz-Ponte C, Castells A, Carracedo A, Ho JW, Sham P, Hofstra RM, Vodicka P, Brenner H, Hampe J, Schafmayer C, Tepel J, Schreiber S, Völzke H, Lerch MM, Schmidt CA, Buch S, Moreno V, Villanueva CM, Peterlongo P, Radice P, Echeverry MM, Velez A, Carvajal-Carmona L, Scott R, Penegar S, Broderick P, Tenesa A, Houlston RS. COGENT (COlorectal cancer GENeTics): an international consortium to study the role of polymorphic variation on the risk of colorectal cancer. Br J Cancer. 2010 Jan 19;102(2):447-54. doi 10.1038/sj.bjc.6605338.

2009

17 Ammerpohl O, Martín-Subero JI, Richter J, Vater I, Siebert R. Hunting for the 5th base: Techniques for analyzing DNA methylation. Biochim Biophys Acta. 2009 Sep;1790(9):847-62.

16 Arlt A, Bauer I, Schafmayer C, Tepel J, Sebens-Müerköster S, Brosch M, Röder C, Kalthoff H, Hampe J, Moyer MP, Fölsch UR, Schäfer H. Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of Nuclear factor E2-related factor 2 (Nrf2). Oncogene 2009; 28(45):3983-96

15 Hemminki K, Försti A, Lorenzo Bermejo J. Surveying the genomic landscape of colorectal cancer. Am J Gastroenterol 2009;104:789-90. doi 10.1038/ajg.2008.100

14 Hemminki K, Li X, Sundquist J, Sundquist K. Cancer risks in Crohn disease patients. Ann Oncol 2009;20:574-80. doi 10.1093/annonc/mdn595

13 Möckelmann N, von Schönfels W, Buch S, von Kampen O, Sipos B, Egberts JH, Rosenstiel P, Franke A, Brosch M, Hinz S, Röder C, Kalthoff H, Fölsch UR, Krawczak M, Schreiber S, Bröring CD, Tepel J, Schafmayer C, Hampe J. Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer. BMC Gastroenterol. 2009 20;9:79.

12 Pechlivanis S, Lorenzo Bermejo J, Pardini B, Naccarati A, Vodickova L, Novotny J, Hemminki K, Vodicka P, Försti A. Genetic variation in adipokine genes and risk of colorectal cancer. Eur J Endocrinol 2009 Jun;160(6):933-40. doi 10.1530/EJE-09-0039

11 Schafmayer C, Buch S, Völzke H, von Schönfels W, Egberts JH, Schniewind B, Brosch M, Ruether A, Franke A, Mathiak M, Sipos B, Henopp T, Catalcali J, Hellmig S, Elsharawy A, Katalinic A, Lerch MM, John U, Fölsch UR, Fändrich F, Kalthoff H, Schreiber S, Krawczak M, Tepel J, Hampe J. Investigation of the colorectal cancer susceptibility region on chromosome 8q24.21 in a large German case-control sample. Int J Cancer. 2009 Jan 1;124(1):75-80.

2008

10 Hemminki K, Försti A, Bermejo JL. New cancer susceptibility loci: population and familial risks. Int J Cancer 2008;123:1726-29. doi 10.1002/ijc.23702

9 Hemminki K, Försti A, Bermelo JL. The ?common disease-common variant? hypothesis and familial risks. Plos ONE 2008;3:e2504 doi 10.1371/journal.pone.0002504

8 Hemminki K, Li X, Sundquist J, Sundquist K. Cancer risks in ulcerative colitis patients. Int J Cancer 2008;123:1417-21. doi 10.1002/ijc.23666

7 Hemminki K, Li X, Sundquist K, Sundquist J. Do inflammatory bowel disease and cancer share sus-ceptibility: A family study. Inflamm Bowel Dis 2008;14:1167-8. doi 10.1002/ibd.20427

6 Houlston RS, Webb E, ... Hampe J, Buch S, Schafmayer C, ? Dunlop MG. Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat Genet. 2008 Dec;40(12):1426-35

5 Melum E, Buch S, Schafmayer C, Kalthoff H, Tepel J, Schreiber S, Karlsen TH, Hampe J. Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma. Intl. J. Cancer 2008, 123(1):241-2.

4 Pittman AM, Webb E, Carvajal-Carmona L, Howarth K, Di-Bernardo M, Broderick P, Spain S, Walther A, Price A, Sullivan K, Twiss P, Fielding S, Rowan A, Jaeger E, Vijayakrishnan J, Chandler I, Penegar S, Qureshi M, Lubbe S, Domingo E, Kemp Z, Barclay E, Wood W, Martin L, Gorman M, Thomas H, Peto J, Bishop T, Gray R, Maher ER, Lucassen A, Kerr D, Evans GR; The CORGI Consortium, van Wezel T, Morreau H, Wijnen JT, Hopper JL, Southey MC, Giles GG, Severi G, Castellví-Bel S, Ruiz-Ponte C, Carracedo A, Castells A; The EPICOLON Consortium, Försti A, Hemminki K, Vodicka P, Naccarati A, Lipton L, Ho JW, Cheng KK, Sham PC, Luk J, Agúndez JA, Ladero JM, de la Hoya M, Caldés T, Niittymäki I, Tuupanen S, Karhu A, Aaltonen L, Cazier JB, Tomlinson IP, Houlston RS. Refinement of the basis and impact of common 11q23.1 variation to the risk of developing colo-rectal cancer. Hum Mol Genet 2008;17:3720-7. doi 10.1093/hmg/ddn267

3 Tenesa A, Farrington SM, ? Schafmayer C, Tepel J, Schreiber S, Völzke H, Schmidt CO, Hampe J, ? Campbell H, Dunlop MG. Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21. Nature Genetics 2008, 40(5):631-7

2 Tomlinson IP, Webb E, Carvajal-Carmona L, Broderick P, Howarth K, Pittman AM, Spain S, Lubbe S, Walther A, Sullivan K, Jaeger E, Fielding S, Rowan A, Vijayakrishnan J, Domingo E, Chandler I, Kemp Z, Qureshi M, Farrington SM, Tenesa A, Prendergast JG, Barnetson RA, Penegar S, Barclay E, Wood W, Martin L, Gorman M, Thomas H, Peto J, Bishop DT, Gray R, Maher ER, Lucassen A, Kerr D, Evans DG; The CORGI Consortium, Schafmayer C, Buch S, Völzke H, Hampe J, Schreiber S, John U, Koessler T, Pharoah P, van Wezel T, Morreau H, Wijnen JT, Hopper JL, Southey MC, Giles GG, Severi G, Castellví-Bel S, Ruiz-Ponte C, Carracedo A, Castells A; The EPICOLON Consortium, Försti A, Hemminki K, Vodicka P, Naccarati A, Lipton L, Ho JW, Cheng KK, Sham PC, Luk J, Agúndez JA, Ladero JM, de la Hoya M, Caldés T, Niittymäki I, Tuupanene S, Karhu A, Aaltonen L, Cazier JB, Campbell H, Dunlop MG, Houlston RS. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 2008;40:623-30.

1 Tulupova E, Kumar R, Hanova M, Slyskova J, Pardini B, Polakova V, Naccarati A, Vodickova L, No-votny J, Halamkova J, Hemminki K, Vodicka P. Do polymorphisms and haplotypes of mismatch re-pair genes modulate risk of sporadic colorectal cancer? Mutat Res 2008;648:40-5. doi 10.1016/j.mrfmmm.2008.09.005