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34 Copanaki, E., Chang, S., Vlachos, A., Tschäpe, J.-A., Müller, U. C., Kögel, D., Deller, T. sAPP? antagonizes dendritic degeneration and neuron death triggered by proteasomal stress. Mol Cell Neurosci 44:386-393
33 Endres, K and Fahrenholz, F. Upregulation of the alpha-secretase ADAM10 - risk or reason for hope?. FEBS J 2010; 277: 1585-1596
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31 Feulner TM, Laws SM, Friedrich P, Wagenpfeil S, Wurst SH, Riehle C, Kuhn KA, Krawczak M, Schreiber S, Nikolaus S, Förstl H, Kurz A, Riemenschneider M. Examination of the current top candidate genes for AD in a genome-wideassociation study. Mol Psychiatry. 2010;15(7):756-66. [Epub ahead of print]
30 Grösgen, S., M.O. Grimm, P. Friess, T. Hartmann T. Role of amyloid beta inlipid homeostasis. Biochim Biophys Acta 1801: 966-974.
29 Laws SM, Eckart K, Friedrich P, Eisele T, Kurz A, Förstl H, Riemenschneider M. No association of lipase C polymorphisms with Alzheimer´s disease. Neurobiol Aging. 2010;31(12):2192-3. [Epub ahead of print 2009]
28 Schebelle L, Wolf C, Stribl C, Javaheri T, Schnütgen F, Ettinger A, Ivics Z, Hansen J, Ruiz P, von Melchner H, Wurst W, Floss T. Efficient conditional and promoter-specific in vivo expression of cDNAs of choice by taking advantage of recombinase-mediated cassette exchange using FlEx gene traps. Nucleic Acids Res. 2010 May 38 (9): e106.
27 Timmermann B, Kerick M, Roehr C, Fischer A, Isau M, Boerno ST, Wunderlich A, Barmeyer C, Seemann P, Koenig J, Lappe M, Kuss AW, Garshasbi M, Bertram L, Trappe K, Werber M, Herrmann BG, Zatloukal K, Lehrach H, Schweiger MR. Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. PLoS One. 2010 Dec 22;5(12):e15661.
26 Vinayagam A, Stelzl U, Wanker EE. Repeated two-hybrid screening detects transient protein-protein
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25 Chaurasia G, Malhotra S, Russ J, Schnoegl S, Hänig C, Wanker EE, Futschik Me. UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome. Nucl. Acids Res. 2009 Jan; 37 (suppl_1):D657-660. doi 10.1093/nar/gkn841
24 Diehl-Schmid J, Grimmer T, Laws SM, Neumann M, Perneczky R,Riemenschneider M, Kurz A, Förstl H. [Frontotemporal lobar degeneration. Part 1: diagnosis and treatment]. Fortschr Neurol Psychiatr. 2009 Mar;77(3):169-76; quiz 177-9. Epub 2009 Mar 12. Review. German.
23 Diehl-Schmid J, Neumann M, Laws SM, Perneczky R, Grimmer T, Danek A, Kurz A, Riemenschneider M, Förstl H. [Frontotemporal lobar degeneration]. Fortschr Neurol Psychiatr. 2009 May;77(5):295-304. Epub 2009 Apr 1. Review. German.
22 Drzezga A, Grimmer T, Henriksen G, Mühlau M, Perneczky R, Miederer I, Praus C, Sorg C, Wohlschläger A, Riemenschneider M, Wester HJ, Foerstl H, Schwaiger M, Kurz A. Effect of APOE genotype on amyloid plaque load and gray matter volume in Alzheimer disease. Neurology. 2009 Apr 28;72(17):1487-94. Epub 2009 Apr 1.
21 Endres K, Mitteregger G, Kojro E, Kretzschmar H, Fahrenholz F.Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo. Neurobiol Dis. 2009 Nov;36(2):233-41. Epub 2009 Jul 24.
20 Frank S, Copanaki E, Burbach G, Müller UC, Deller T (2009) Differential regulation of toll-like receptor mRNAs in amyloid plaque-associated brain tissue of aged APP23 transgenic mice. Neurosci Lett 2009; 453: 41-4
19 Freese C, Garratt AN, Fahrenholz F, Endres K. The effects of alpha-secretase ADAM10 on the proteolysis of neuregulin-1. FEBS J. 2009 Mar; 276(6): 1568-1580. (doi 10.1111/j.1742-4658.2009.06889.x)
18 Friedrich P, Feulner TM, Laws SM, Eckart K, Perneczky R, Kurz A, Förstl H, Riemenschneider M. No association of Tachykinin receptor 2 (TACR2) polymorphisms with Alzheimer´s disease. Neurobiol Aging. 2009. [Epub ahead of print]
17 Grimmer T, Riemenschneider M, Förstl H, Henriksen G, Klunk WE, Mathis CA, Shiga T, Wester HJ, Kurz A, Drzezga A. Beta amyloid in Alzheimer´s disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid. Biol Psychiatry. 2009;65(11):927-34. [Epub 2009 Mar 6]
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15 Laws SM, Eckart K, Friedrich P, Eisele T, Kurz A, Förstl H, Riemenschneider M. No association of lipase C polymorphisms with Alzheimer´s disease. Neurobiol Aging. 2009. [Epub ahead of print]
14 Laws SM, Eckart K, Friedrich P, Kurz A, Förstl H, Riemenschneider M. Lack of evidence to support the association of polymorphisms within the alpha- and beta-secretase genes (ADAM10/BACE1) with Alzheimer´s disease. Neurobiol Aging. 2009 [Epub ahead of print]
13 Lourenço FC, GalvanV, Fombonne J, Corset V, Llambi F, Müller U, Bredesen DE, Mehlen P (2009) Netrin-1 interacts with amyloid precursor protein and regulates amyloid-production. Cell Death Diff 2009; 16:655-663
12 Mallm, J.-P., Jakob-Andreas Tschäpe, J. A., Hick, M., Filippov, M. A. and C. Müller, U. C. (2009). Generation of conditional null alleles for APP and APLP2. Genesis 48: 200. (DOI: 10.1002/dvg.20601)
11 Prinzen C, Trümbach D, Wurst W, Endres K, Postina R, Fahrenholz F. Differential gene expression in ADAM10 and mutant ADAM10 transgenic mice. BMC Genomics. 2009 Feb 5;10:66.
10 Schumacher A, Friedrich P, Diehl-Schmid J, Ibach B, Perneczky R, Eisele T, Vukovich R, Foerstl H, Riemenschneider M. No association of TDP-43 with sporadic frontotemporal dementia. Neurobiol Aging. 2009;30(1):157-9.
9 Szodorai A, KuanY-H, Hunzelmann S, Engel U, Sakane A, Sasaki T, Takai Y, Kirsch J, Müller U, Beyreuther K, Brady S, Morfini G, Kins S (2009) APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. J Neurosci 2009; 29: 14534-44
8 Uhrig M, Ittrich C, Wiedmann V, Knyazev Y, Weninger A, Riemenschneider M,Hartmann T. New Alzheimer amyloid beta responsive genes identified in human neuroblastoma cells by hierarchical clustering. PLoS One. 2009 Aug 26; 4(8):e6779.
7 Uhrig, M., P. Brechlin, O. Jahn, Y. Knyazev, A. Weninger, L. Busia, M. Otto, and T. Hartmann, (2008). Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Abeta42 reduces the differentiation potential. BMC Medicine 6:38 (available 2009)
6 Venkatesan K, Rual JF, Vazquez A, Stelzl U, Lemmens I, Hirozane-Kishikawa T, Hao T, Zenkner M, Xin X, Goh KI, Yildirim MA, Simonis N, Heinzmann K, Gebreab F, Sahalie JM, Cevik S, Simon C, de Smet AS, Dann E, SmolyarA, Vinayagam A, Yu H, Szeto D, Borick H, Dricot A, Klitgord N, Murray RR, Lin C, Lalowski M, Timm J, Rau K, Boone C, Braun P, Cusick ME, Roth FP, Hill DE, Tavernier J, Wanker EE, Barabási AL, Vidal M. An empiricalframework for binary interactome mapping. Nature Methods. 2009 Jan; 6 (1):83-90. doi 10.1038/nmeth.1280
5 Vukovich R, Perneczky R, Drzezga A, Förstl H, Kurz A, Riemenschneider M. Brain metabolic correlates of cerebrospinal fluid beta-amyloid 42 and tau in Alzheimer´s disease. Dement Geriatr Cogn Disord. 2009;27(5):474-80. [Epub 2009 May 12]
4 Wegenast-Braun BM, Fulgencio Maisch A, Eicke D, Radde R, Herzig MC, Staufenbiel M, Jucker M, Calhoun ME (2009) Independent effects of intra- and extracellular A on learning-related gene expression. American Journal of Pathology 2009; 175: 271-282
3 Willem M, Lammich S, Haass C. 1. Function, regulation and therapeutic properties of beta-secretase (BACE1). Semin Cell Dev Biol. 2009 Apr;20(2):175-82.
2008
2 Gakhar-Koppole N, Hundeshagen P, Mandl C, Weyer SW, Alliquant B, Müller U, Ciccolini F (2008) Activity requires soluble amyloid precursor protein to promote neurite outgrowth in neural stem cell-derived neurons via activation of MAPK pathway. Eur J Neurosci 28:871-882
1 Gross E, Busse B, Riemenschneider M, Neubauer S, Seck K, Klein HG, Kiechle M, Lordick F, Meindl A. Strong association of a common dihydropyrimidine dehydrogenase gene polymorphism with fluoropyrimidine-related toxicity in cancer patients. PLoS One. 2008;3(12):e4003. Epub 2008 Dec 23.
