NGFN Facts and Figures

4. Patents from NGFN-1, NGFN-2, NGFN-Plus and NGFN-Transfer

Taking the fast lane from research to utilization

The application of research results from NGFN-Plus and NGFN-Transfer is an important aim of the Program of Medical Genome Research. A crucial step for the practical application is the filing of patents for protectable inventions and developments. Therefore the number of patents is a measure for the utilization of NGFN research.
The diagram shows the number of patents granted in the respective funding periods of NGFN. For the current reporting period all 43 filed patents were counted.





Patents of NGFN-Plus und NGFN-Transfer 2008 - 2013

Genome Network Obesity
Patent number: EP09014856.0
    Title: A method for diagnosing metabolic syndrome, obesity and/or diabetes
    Inventor: Schürmann-Bartsch, Scherneck, Vogel, Joost
    Applicant: Deutsches Institut für Ernährungsforschung
    State: withdrawn; Priority date: 30.11.2009
Patent number: EP12161060.4/ US 61/814,758 (Together with Genome Network
    DiGtoP)
    Title: A novel method of producing an oocyte carrying a modified target sequence in
    its genome    
    Inventor: Kühn, Wurst, Meyer
    Applicant: Helmholtz Zentrum München
    State: Patent application filed and technology in commercial exploitation;
    Priority date: 23.03.2012
Patent number: EP13153142.8
    Title: Foam cell specific Liver X Receptor (LXR) alpha agonist, SIRT1 inhibitors as well
    as p300 inhibitors as pharmaceutically active agents
    Inventor: S. Sauer, S. Holzhauser, R. Feldmann, A. Geikowski
    Applicant: Max-Planck-Gesellschaft;
    Priority date: 29.1.2013
Patent number: EP13165716.5
    Title: PPARgamma Modulators
    Inventor: S. Sauer. C. Weidner, M. Kliem
    Applicant: Max-Planck-Gesellschaft, Priority date: 29.4.2013

Genome Network Heart Failure
Patent number: US61/219,125
    Title: Polynucleotides for diagnostic and prognostic of a cardiac disease
    Inventor: Gotthardt, Hübner, Graeser, Guo
    Applicant: MDC Berlin
    State: Patent application filed and technology in commercial exploitation;
    Priority date: 22.06.2009

Genome Network Herpes virus infection
Patent number: EP11002480
    Title: Micro RNA Inhibiting Nucleic Acid Molecule
    Inventor: Lars Dölken, Ulrich Koszinowski, Sebastien Pfeffer
    Applicant: Lars Dölken, LMU München
    State: Released to the inventor; Priority date: 24.03.2011
Patent number: EP11306102.2
    Title: MicroRNAs from human herpesvirus 6
    Inventor: Lars Dölken, Sebastien Pfeffer, Lee Tuddenham, Jette Jung
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    State: Pending; Priority date: 06.09.2011

Genome Network Pancreatic Cancer
Patent number: EP10001596.5
    Title: Means and methods for diagnosing pancreatic cancer
    Inventor: Christoph Schröder, Jörg Hoheisel, Tatjana Crnogorac-Jurcevic
    Applicant: DKFZ Heidelberg
    State: Pending; Priority date: 17.02.2010
Patent number: EP11169588.8
    Title: Prediction of recurrence for superficial bladder cancer by protein signature in
    tissue samples
    Inventor: Hoheisel, Radvanyi, Srinivasan, Schröder
    Applicant: DKFZ und Institut Curie
    State: Pending; Priority date: 10.06.2011
Patent number: US61/536,486   
    Title: Methods and composition involving miR-135b for distinguishing pancreatic
    cancer from  benign pancreatic disease   
    Inventor: Alex Adai, Anna Szafranska-Schwarzbach, Bernard Andruss, Stephan
    Albrecht Hahn Applicant: Universität Bochum, ASURAGEN
    State: Released; Priority date: 19.09.2011
Patent number: DE102011108254.2; DE102012005153.0   
    Title: Pantumormarker II (snRNA RNU2-1 as a tumor marker)
    Inventor: A. Baraniskin, S. Hahn, W. Schmiegel
    Applicant: Universität Bochum
    State: Patent application filed and technology in commercial exploitation;
    Priority date: 16.03.2012
   
Genome Network Brain Tumor
Patent number: EP09006620.0
    Title: Diagnostic methods for the prognosis of a brain tumor
    Inventor: von Deimling, Hartmann, Zentgraf, Reifenberger, Capper, Weller, Wick
    Applicant: DKFZ, Ruprecht-Karls-Universität Heidelberg
    State: Pending; Priority date: 15.05.2009
Patent number: US61/334,812
    Title: Methods for the diagnosis and prognosis of a tumor using BCAT1 protein
    Inventor: Radlwimmer, Barbus, Tönjes, Tödt, Lichter, Reifenberger
    Applicant: DKFZ Heidelberg
    State: Pending; Priority date: 14.05.2010
Patent number: EP11000720.0
    Title: Inhibitors of branched-chain-aminotransferase-1 (BCAT1) for the treatment of
    neoplasia   
    Inventor: Bernhard Radlwimmer, Sebastian Barbus, Martje Tönjes, Peter Lichter
    Applicant: DKFZ
    State: Pending; Priority date: 28.01.2011
Patent number: US61/388,158; US61/503,950
    Title: Means and methods for diagnosing cancer using an antibody which specifically
    binds to BRAF V600E
    Inventor: von Deimling, Capper
    Applicant: DKFZ, Ruprecht-Karls-Universität Heidelberg   
    State: Patent application filed and technology in commercial exploitation;
    Priority date: 30.09.2010; 01.07.2011

Genome Network Leukemia
Patent number: EP10004898.2
    Title: Risk prognosis method for chronic lymphocytic leukemia
    Inventor: Herold, Jurinovic, Buske, Bohlander
    Applicant: Ludwig-Maximilians-Universität München
    State: Pending; Priority date: 07.05.2010

Genome Network Mutanom
Patent number: EP09158709.7
    Title: Use of MLKL in cancer therapy
    Inventor: Mollenhauer, Hudler, Blaich, Wittig
    Applicant: DKFZ
    State: Pending; Priority date: 24.04.2009

Genome Network Neuroblastoma
Patent number: DE102010024300.0 / DE102010024512.7
    Title: Neue Ansätze für die Tumortherapie-Histondemethylasen
    Inventor: PD Dr. Alexander Schramm, Dr. Johannes Schulte, Prof. Dr. Angelika Eggert
    Applicant: Universität Duisburg-Essen
    State: Released by ProVendis: Priority date: 21.06.2010

Genome Network Cancer Genes
Patent number: EP09005492.5; US61/170,375
    Title: Development of fluorescently P-loop labeled kinases for screening of inhibitors
    Inventor: Rauh, Daniel; Simard, Jeffrey
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.,
    Hofgartenstr. 8, 80539 München
    State: Pending; Priority date: 17.04.2009
Patent number: EP08013340.8; US61/083,335; EP08020331.7; EP09005493.3
    Title: Fluorescently or spin-labeled kinases for rapid screening and identification of
    novel kinase inhibitor scaffolds
    Inventor: Rauh, Daniel; Simard, Jeffrey; Getlik, Matthäus;
    Applicant: Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V.,
    Hofgartenstr. 8, 80539 München;
    State: Pending; Priority date: 17.04.2009
Patent number: EP09177117.0
    Title: Pyrosequencing method for predicting the response of a patient towards anti
    cancer treatment, European Patent application
    Inventor: Altmüller, Nürnberg, Querings
    Applicant: Universität zu Köln
    State: Pending; Priority date: 25.11.2009
Patent number: EP11164480.3
    Title: Blood-based gene detection of non-small cell lung cancer
    Inventor: Hofmann, Schultze, Staratschek-Jox, Wolf, Zander
    Applicant: Rheinische Friedrich-Wilhelms-Universität Bonn, Universität zu Köln
    State: Pending; Priority date: 02.05.2011
Patent number: US 61/529,476; EP11007082.8
    Title: Labeled phosphatases for the screening of inhibitors
    Inventor: Rauh, Daniel; Simard, Jeffrey; Waldmann, Herbert
    Applicant: Max-Planck-Gesellschaft
    Priority date: 31.08.2011
Patent number: EP12153907.6
    Title: Novel fusion genes in lung cancer
    Inventor: Thomas, Roman; Heuckmann, Johannes; Fischer, Florian; Fernandez-
    Cuesta, Lynnette
    Applicant: Max-Planck-Gesellschaft
    State: Patent application filed and technology in commercial exploitation;
    Priority date: 03.02.2012
 
Genome Network Prostate Cancer
Patent number: DE202009008601.1 (Together with Genome Network Cellular Systems
    Genomics)
    Title: Inkubationsschale für Hochdurchsatzverfahren bei Protein-Array-Inkubationen
    (Gebrauchsmuster)
    Inventor: Mannsperger, Schmidt, Korf, Fink, Kameke
    Applicant: DKFZ; Metecon GmbH
    State: Published; Priority date: 19.06.2009
Patent number: EP09174455.7
    Title: Circulating miRNAs as non-invasive markers for diagnosis and staging in
    prostate cancer
    Inventor: Jan C. Brase, Marc Johannes, Thorsten Schlomm, Maria Fälth, Alexander
    Haese, Thomas Steuber, Tim Beissbarth, Ruprecht Kuner, Holger Sültmann
    Applicant: DKFZ und Uni Göttingen und Uniklinikum HH-Eppendorf
    State: Pending; Priority date: 29.10.2009
Patent number: EP 11162979.6
    Title: Epigenetische Marker zur Prostata-Tumor-Diagnostik (Prostate cancer markers)
    Inventor: R. Schweiger, H. Lehrach, S. Börno, H. Sültmann, T. Schlomm, G. Sauter
    Applicant: Max-Planck-Gesellschaft und DKFZ
    State: Submitted; Priority date: 19.04.2011

Genome Network Colon Cancer
Patent number: EP12180459.5
    Title: : Biomarkers for colon cancer
    Inventor: Schweiger, Michal-Ruth; Grimm, Christina; Herwig, Ralf; Lehrach, Hans
    Applicant: Max-Planck-Gesellschaft
    Priority date: 14.08.2012

Genome Network Neurodegeneration
Patent number: EP11161325.3
    Title: Phenoxazinones or phenothiazones as inhibitors of amyloid formation
    Inventor: Wanker, Herbst, Bieschke, Wagner, Wiglenda, Schmidt, Böddrich
    Applicant: MDC Berlin
    State: Pending; Priority date: 06.04.2011

Genome Network Cellular Systems Genomics
Patent number: DE202009008601.1 (Together with Genome Network Prostate Cancer)
    Title: Inkubationsschale für Hochdurchsatzverfahren bei Protein-Array-
    Inkubationen (Gebrauchsmuster)
    Inventor: Mannsperger, Schmidt, Korf, Fink, Kameke
    Applicant: DKFZ; Metecon GmbH
    State: Published; Priority date: 19.06.2009
Patent number: EP12154916.6
    Title: Biomarker set for identifying a severe form of cancer
    Inventor: Korf, Ulrike; Wiemann, Stefan; Bender, Christian; Sonntag, Johanna
    Applicant: DKFZ; Priority date: 10.02.2012

Genome Network DiGtoP
Patent number: EP09014709.1, EP09014889.1, US61/264,514, US 61/265,296
    Title: Conditional expression of transgenes in vivo
    Inventor: L. Schebelle (HMGU), F. Schnütgen (Uni Frankfurt), T. Floss (HMGU)
    Applicant: Helmholtz Zentrum München, Uni Frankfurt
    State: Pending; Priority date: 25.11.2009; 30.11.2009; 01.12.2009
Patent number: US61/255,621
    Title: Homologous recombination in the oocyte
    Inventor: Ralf Kühn, Melanie Meyer, Wolfgang Wurst
    Applicant: Ralf Kühn, Melanie Meyer, Wolfgang Wurst; Helmholtz Zentrum München   
    State: Pending; Priority date: 28.10.2009
Patent number: EP10005863.5/ US61/352,103
    Title: Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a
    nonspecific cleavage domain of a restriction nuclease and their use
    Inventor: Kühn, Wurst, Meyer
    Applicant: Helmholtz Zentrum München
    State: Pending; Priority date: 07.06.2010
Patent number: EP11004637.2
    Title: Improved Recombination Efficiency by Inhibition of NHEJ DNA Repair
    Inventor: Kühn, Wurst
    Applicant: Helmholtz Zentrum München
    State: Pending, Priority date: 07.06.2011
Patent number: EP11004635.6
    Title: Protein having nuclease activity, fusion proteins and uses thereof
    Inventor: Kühn
    Applicant: Helmholtz Zentrum München
    State: Pending, Priority date: 07.06.2011
Patent number: EP10009584.3; 13/823,431 / 10 009 584.3
    Title: HOT1 and uses thereof
    Inventor: Dr. D. Kappei, Prof. Dr. F. Buchholz, Prof. Dr. M. Mann, Dr. F. Butter
    Applicant: Max-Planck-Innovation GmbH
    State: Pending; Priority date: 14.09.2010
Patent number: EP12161060.4/ US 61/814,758 (Together with Genome Network
    Obesity)
    Title: A novel method of producing an oocyte carrying a modified target sequence in
    its genome    
    Inventor: Kühn, Wurst, Meyer
    Applicant: Helmholz Zentrum München
    State: Patent application filed and technology in commercial exploitation;
    Priority date: 23.03.2012
Patent number: EP131507063.2
    Title: Gene editing in the oocyte by Crispr-Cas9 nucleases
    Inventor: Kühn, Wurst, Ortiz
    Applicant: Helmholtz Zentrum München
    State: Pending; Priority date: 15.02.2013

Genome Network Environment-related Diseases
Patent number: PCT/EP2008/008491
    Title: Method for identifying an increased susceptibility to ulcerative colitis
    Inventor: Schreiber, Franke
    Applicant: Universität Kiel
    State: Pending, Priority date: 08.10.2008
Patent number: US61/113,342; EP09006623.4-2403
    Title: X-chromosomal variation as a diagnostic and therapeutic marker for the
    progression to AIDS
    Inventor: Siddiqui, Roman; Sauermann, Ulrike; Altmüller, Janine; Nürnberg, Peter;
    Fritzer, Elfriede; Nothnagel, Michael; Krawczak, Michael; Platzer, Mathias
    Applicant: Deutsches Primatenzentrum GmbH; Leibniz-Institut für Altersforschung
    Fritz-Lipmann-Institut e.V.; Universität zu Köln; Christian-Albrechts-Univ. zu Kiel
    State: Pending; Priority date: 11.11.2008, 15.05.2009

Innovation Alliance Anti-malarial Agents
Patent number: US61/110,217
    Title: Use of inhibitors of host kinases for the treatment of infectious diseases
    Inventor: Hannus, Martin, Mota, Prudencio, Rodrigues
    Applicant: Cenix BioScience GmbH, Instituto de Medicina Molecular, Faculdade de
    Medicina da Universidade de Lisboa
    State: Pending; Priority date: 31.10.2008

Innovation Alliance Metabolomic Signatures of Heart Failure
Patent number: US61/299,360; EP10000915.8
    Title: Means and methods for diagnosing heart failure in a subject
    Inventor: Fuhrmann, Reszka, Kastler, Busch, Leibold, Katus, Frey, Weis, Wolf
    Applicant: Metanomics GmbH und Universität Heidelberg
    State: Pending; Priority date: 29.01.2010

Innovation Alliance New Tools CVD
Patent number: EP09171773.6
    Title: Vasoactive peptide and derivatives thereof
    Inventor: Prof. Dr. J. Jankowski, Dr. V. Jankowski, Prof. Dr. W. Zidek, Dr. A. Kretschmer,
    Prof. Dr. R. Santos, Prof. Dr. M. van der Giet
    Applicant: Bayer Schering Pharma AG, Charité Universitätsmedizin Berlin
    State: Pending; Priority date: 30.09.2009

Innovation Alliance WTA Amplification Methods for Biobanks
Patent number: DE102009024143.4
    Title: Amplifikation komplexer Nukleinsäuren
    Inventor: Korfhage, Fisch
    Applicant: Qiagen GmbH
    State: Pending; Priority date: 04.06.2009

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