Breakthrough in the Research of Rare Neurodegenerative Diseases

The tauopathy progressive supranuclear palsy (PSP) is a neurodegenerative disease occurring mostly at advanced age and counting among the atypical Parkinson syndromes. Up to now PSP is irremediable and always terminal. To date, the molecular causes of the disease were unknown. Now an international consortium under the guidance of PD Dr. Günter Höglinger at the Neurology Clinics in Marburg and Prof. Dr. Ulrich Müller, Director at the Institute for Human Genetics at the University Gießen, identified genes, whose dysfunction contribute to the development of PSP.

Publication:
Höglinger et al.: Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. Nature Genetics 2011 Jun 19, doi: 10.1038/ng.859