Genetic Causes of Heart Attack are Deeply Ingrained

An international consortium has defined more precisely the impact of the congenital factor on cardiac infarction. The international team headed by NGFN scientists Prof. Dr. Jeanette Erdmann, Lübeck, and Prof. Dr. Heribert Schunkert, Munich, identified 104 genetic loci, strongly associated with the risk of developing a cardiac infarction. In total, 46 chromosomal sections are now identified, that  are confirmed to cause this threatening disease with genome wide significance. Thus the risk of a heart attack is much deeper ingrained than assumed so far.

Publikation:
The CARDIoGRAMplusC4D Consortium (2012) ‘Large-scale association analysis identifies new risk loci for coronary artery disease’ Published online in Nature Genetics on 02 December 2012 Doi: 10.1038/ng.2480

Contact:
Prof. Dr. rer. nat. Jeanette Erdmann
Institut für Integrative und Experimentelle Genomik
Universität zu Lübeck
Ratzeburger Allee 160
D-23538 Lübeck
Phone: +49-451-500-4857
Fax: +49-451-500-6437
E-mail: jeanette.erdmann@uksh.de

Prof. Dr. med. Heribert Schunkert
Deutsches Herzzentrum München
Klinik für Herz- und Kreislauferkrankungen
Technische Universität München
Lazarettstraße 36
D-80636 München
Phone: +49-89-1218-4073
Fax: +49-89-1218-4013
E-mail: schunkert@dhm.mhn.de