Infections and Inflammations
Infection means the entry, colonization and multiplication of microorganisms (bacteria, viruses, fungi, parasites) in a host organism. In an infection, the infecting organism seeks to utilize the host's resources to multiply, usually at the expense of the host.
An inflammation is the response of the host’s immune system to internal or external stimuli (microorganisms, pressure, radiation). Induced by the actions of various inflammatory mediators, the blood supply increase induces the recruitment of leukocytes, which then start the elimination of the contaminants and the damaged tissue.

Along with cardiovascular diseases, infectious diseases are the most common cause of death worldwide, many infectious diseases such as AIDS, hepatitis, BSE or avian flu cannot be healed. Thus, there is a great demand for research into the causes, progress and treatment of infections, especially because of increasing resistance of pathogens against known drugs.

Scientists of the NGFN investigate the molecular principles of the addressed infections to provide novel and efficient strategies in the fight against these diseases. Using functional genomics they investigate the reactions of the human organism to infections with different pathogens to develop new strategies for therapy.
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