The clinical pictures are as divers as stroke, neurodegenerative disorders like Alzheimer's disease and Parkinson's disease, tumors or injury of neuronal tissue, multiple sclerosis, addiction, migraine and epilepsy.
Some of the neurological disorders like Alzheimer's disease, stroke and Parkinson's disease primarily affect older persons. For example about 5% of men and 6% of women over 60 years of age are affected with Alzheimer's. According to the WHO, an estimated 37 million people worldwide live with dementia - with Alzheimer's disease causing the majority of cases. With the ageing of populations, this figure is projected to increase rapidly over the next 20 years.
Amongst others, genetic factors play a role for many of the diseases of the nervous system. That is why they are subject of the human genome research. Various research groups in the NGFN work intensively to identify the alterations in genes and reveal the molecular mechanisms that underlie the onset and process of the respective disorders. This knowledge generates the basis for the effective improvement of diagnosis and therapy prospects.