NGFN-TRANSFER

Decoy oligodeoxynucleotide drug targets in heart failure

Coordinator:    Dr. Beate Berghöfer
Institution: AVONTEC GmbH, Martinsried
Homepage: www.avontec.com/
Primary objective of subproject 1 was the optimization of already developed decoy ODNs against the transcription factors AP-1 and NF-IL6, including the development of appropriate control oligonucleotides. After the withdrawal of the industrial partner AVONTEC GmbH effective on 31.12.2009 the subproject was gradually integrated into subproject 2 under the direction of Prof. Hecker.

Additional relevant Internet-links:
Institut für Physiologie und Pathophysiologie, Universität Heidelberg
Abt. Innere Medizin III: Kardiologie, Angiologie und Pneumologie

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