2013
31 Suter B, Fontaine JF, Yildirimman R, Rasko T, Schaefer MH, Rasche A, Porras P, Vazquez-Alvarez BM, Russ J, Rau K, Foulle R, Zenkner M, Saar K, Herwig R, Andrade-Navarro MA, Wanker EE.
2012
30 Dreher, F.; Kreitler, T.; Hardt, C.; Kamburov, A.; Yildirimman, R.; Schellander, K.; Lehrach, H.; Lange, B.M.H.; Herwig, R. DIPSBC - Data Integration Platform for Systems Biology Collaborations BMC Bioinformatics. 2012 May 8;13:85. doi: 10.1186/1471-2105-13-85.
29 Farrall AL, Riemer P, Leushacke M, Sreekumar A, Grimm C, Herrmann BG, Morkel M. Wnt and BMP signals control intestinal adenoma cell fates. Int J Cancer. 2012 Feb 18. doi: 10.1002/ijc.27500.
28 Habermann K. and B.M.H. Lange. New insights into subcomplex assembly and modifications of centrosomal proteins. Cell Div. 2012 Jul 16;7(1):17. doi: 10.1186/1747-1028-7-17.
27 Haupt A, G. Joberty, M. Bantscheff, H. Fröhlich, H. Stehr, M. R. Schweiger, A. Fischer, M. Kerick, S.T. Boerno, A. Dahl, M. Lappe, H. Lehrach, C. Gonzalez, G. Drewes and B.M.H. Lange. Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics. BMC Cancer. 2012 Jan 25;12:38. doi: 10.1186/1471-2407-12-38.
26 Li J, Pandey V, Kessler T, Lehrach H, and Wierling C. Modeling of miRNA and Drug Action in the EGFR-Signaling Pathway PLoS ONE. 2012; 7(1):e30140. doi:10.1371/journal.pone.0030140.
25 Schaefer MH, Fontaine JF, Vinayagam A, Porras P, Wanker EE, Andrade-Navarro MA. HIPPIE: Integrating protein interaction networks with experiment based quality scores. PLoS One. 2012;7(2):e31826.
24 Schaefer MH, Wanker EE, Andrade-Navarro MA. Evolution and function of CAG/polyglutamine repeats in protein-protein interaction networks. Nucleic Acids Res. 2012 Jan 28.
23 Stefan T. Börno, Axel Fischer, Martin Kerick, Maria Fälth, Mark Laible, Jan C. Brase, Ruprecht Kuner, Andreas Dahl, Christina Grimm, Melanie Isau, Christina Röhr, Andrea Wunderlich, Bernd Timmermann, Rainer Claus, Christoph Plass, Markus Graefen, Ronald Simon, Francesca Demichelis, Mark A. Rubin, Guido Sauter, Thorsten Schlomm, Holger Sültmann, Hans Lehrach and Michal R. Schweiger. Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation. Cancer Discov. 2012 Nov;2(11):1024-35. doi: 10.1158/2159-8290.CD-12-0041. Epub 2012 Aug 28.
22 Suter B and Wanker EE. The investigation of binary PPIs with the classical yeast two-hybrid (Y2H) approach, Y2H variants, and other in vivo methods for PPI mapping. Methods Mol Biol. 2012;812:v-vi.
21 Wierling C, Kühn A, Hache H, Daskalaki A, Maschke-Dutz E, Peycheva S, Li J, Herwig R, and Lehrach H. Prediction in the face of uncertainty: a Monte Carlo-based approach for systems biology of cancer treatment. Mutat Res. 2012 Aug 15;746(2):163-70. doi: 10.1016/j.mrgentox.2012.01.005. Epub 2012 Jan 23.
2011
20 Becla, L., Lunshof, J.E., Gurwitz, D., Schulte in den Bäumen, T., Westerhoff, H.V.,Lange, B.M.H., Brand, A. Health Technology Assessment in the era of personalized healthcare. Int. J. Technol. Assess. Health Care, in press (2011).
19 Kerick M, Isau M, Timmermann B, Sültmann H, Herwig R, Krobitsch S, Schaefer G, Verdorfer I, Bartsch G, Klocker H, Lehrach H, Schweiger MR. Targeted high throughput sequencing in clinical cancer settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity. BMC Med Genomics. 2011 Sep 29;4:68.
18 Leushacke M, Spörle R, Bernemann C, Brouwer-Lehmitz A, Fritzmann J, Theis M, Buchholz F, Herrmann BG, Morkel M. An RNA interference phenotypic screen identifies a role for FGF signals in colon cancer progression. PLoS One. 2011;6(8):e23381.
17 Lidia Becla, Jeantine E. Lunshof, David Gurwitz, Tobias Schulte in den Bäumena, Hans V. Westerhoff, Bodo M. H. Lange and Angela Brand. Health technology assessment in the era of personalized health care. International Journal of Technology Assessment in Health Care (2011), 27: 118-126
16 Schweiger M.R., Kerick M., Timmermann B. and M.Isau. The power of NGS technologies to delineate the genome organization in cancer: From mutations to structural variations and epigenetic alterations. Cancer Metastasis Rev. 2011 Jan 27.
15 Stehr H.; Jang, S.-H.J.; Duarte, J.M.; Wierling, C.; Lehrach, H.; Lappe, M.; Lange, B.M.H. The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors. Molecular Cancer, 10:54. (2011).
14 Vinayagam A, Stelzl U, Foulle R, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro MA, Wanker EE. A directed protein interaction network for investigating intracellular signal transduction. Sci Signaling, 4(189):rs8 (2011)
13 Wittig-Blaich SM, Kacprzyk LA, Eismann T, Bewerunge-Hudler M, Kruse P, Winkler E, Strauss WSL, Hibst R, Steiner R, Schrader M, Mertens D, Sültmann H, Wittig R. Matrix-dependent regulation of AKT in hepsin-overexpressing PC3 prostate cancer cells. Neoplasia, Jul;13(7):579-89, 2011
2010
12 Arunachalam V, Stelzl U, Foulle F, Plassmann S, Zenkner M, Timm J, Assmus HE, Andrade-Navarro M, Wanker EE. Constructing directed protein interaction networks for activated EGF/Erk signaling. Molecular Systems Biology. Submitted. 2010
11 Brase JC, Mannsperger H, Frohlich H, Gade S, Schmidt C, Wiemann S, Beissbarth T, Schlomm T, Sültmann H, Korf U. Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification. Proteome Science 2010 June; 8:36 doi:10.1186/1477-5956-8-36
10 Jürchott K, Kuban RJ, Krech T, Blüthgen N, Stein U, Walther W, Friese C, Kie?basa SM, Ungethüm U, Lund P, Knösel T, Kemmner W, Morkel M, Fritzmann J, Schlag PM, Birchmeier W, Krueger T, Sperling S, Sers C, Royer HD, Herzel H, Schäfer R. Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells. PLoS Genet. 2010 Dec 2;6(12):e1001231.
9 Müller, H.; Mirgorodskaya, E.; Steinbrink, S.; Schmidt, D.; Lehmann, V.; Habermann, K.; Gustavsson, N.; Kessler, T.; Ploubidou, A.; Lehrach, H.; Gobom, J.; Boutros, M.; Lange, B.M.H. Proteomic and functional analysis of the Drosophila centrosome. EMBO Journal, 29:3344-3357 (2010)
8 Scholz AK, Klebl BM, Morkel M, Lehrach H, Dahl A, Lange BMH. A flexible multi-well format for immunofluorescence screening microscopy of small molecule inhibitors. Assay Drug Dev Technol. 2010 Sep 13. [Epub ahead of print].
7 Timmermann B. ?, Kerick M. ?, Röhr C., Fischer A., Isau M., Boerno S., Wunderlich A., Barmeyer C., Seemann P., Koenig J., Lappe M., Kuss A.W., Garshasbi M., Bertram L., Trappe K., Werber M., Herrmann B.G., Zatloukal K., Lehrach H. and Michal R. Schweiger. Somatic mutation profiles of MSI and MSS colorectal cancer identified by whole exome next generation sequencing and bioinformatics analysis. PLoS One 2010 Dec 22;5(12):e15661.
6 Vidigal JA, Morkel M, Wittler L, Brouwer-Lehmitz A, Grote P, Macura K, Herrmann BG. An inducible RNA interference system for the functional dissection of mouse embryogenesis. Nucleic Acids Res. 2010 Mar 28. [Epub ahead of print]
5 Vinayagam A; Stelzl U; Wanker EE. Repeated two-hybrid screening detects transient protein-protein interactions. Theoretical Chemistry Accounts 125:613-619
2009
4 Chaurasia G, Malhotra S, Russ J, Schnoegl S, Hänig C, Wanker EE, Futschik Me. UniHI 4: new tools for query, analysis and visualization of the human protein-protein interactome. Nucl. Acids Res. 2009 Jan; 37 (suppl_1):D657-660. doi 10.1093/nar/gkn841
3 Hache H, Wierling C, Lehrach H, and Herwig R.GeNGe: Systematic Generation of Gene Regulatory Networks.Bioinformatics. 2009; 25(9):1205-1207. doi 10.1093/bioinformatics/btp115
2 Müller, H.; Mirgorodskaya, E.; Steinbrink, S.; Schmidt, D.; Lehmann, V.; Habermann, K.; Gustavsson, N.; Kessler, T.; Ploubidou, A.; Lehrach, H.; Gobom, J.; Boutros, M.; Lange, B.M.H. Proteomic and functional analysis of the Drosophila centrosome. The EMBO Journal advance online publication 3 September 2010; doi:10.1038/emboj.2010.210
1 Venkatesan K, Rual JF, Vazquez A, Stelzl U, Lemmens I, Hirozane-Kishikawa T, Hao T, Zenkner M, Xin X, Goh KI, Yildirim MA, Simonis N, Heinzmann K, Gebreab F, Sahalie JM, Cevik S, Simon C, de Smet AS, Dann E, SmolyarA, Vinayagam A, Yu H, Szeto D, Borick H, Dricot A, Klitgord N, Murray RR, Lin C, Lalowski M, Timm J, Rau K, Boone C, Braun P, Cusick ME, Roth FP, Hill DE, Tavernier J, Wanker EE, Barabási AL, Vidal M. An empiricalframework for binary interactome mapping. Nature Methods. 2009 Jan; 6 (1):83-90. doi 10.1038/nmeth.1280
