2013

97 Hoffmann S, Berger IM, Glaser A, Bacon C, Li L, Gretz N, Steinbeisser H, Rottbauer W, Just S, Rappold G (2013)  Islet1 is a direct transcriptional target of the homeodomain transcription factor Shox2 and rescues the Shox2-mediated bradycardia.  Basic Res Cardiol 108:339 doi:10.1007/s00395-013-0339-z

96 Dudek J, Cheng I-F, Balleininger M, Vaz FM, Streckfuss-Bömeke K, Hübscher D, Vukotic M, Wanders RJA, Rehling P, Guan K.  Cardolipin deficiency affects respiratory chain function and organization in an induced pluripotent stem cell model of Barth syndrome.  Stem Cell Res. 2013; doi.10.1016/j.scr.2013.05.005.

2012

95 Bisping E, Ikeda S, Sedej M, Wakula P, McMullen JR, Tarnavski O, Sedej S, Izumo S, Pu WT, Pieske B.  Transcription factor GATA4 is activated but not required for insulin like growth factor 1-induced cardiac hypertrophy. J Biol Chem. 2012 Jan 6. [Epub ahead of print].

94 Donlin LT, Andresen C, Just S, Rudensky E, Pappas CT, Kruger M, Jacobs EY, Unger A, Zieseniss A, Dobenecker MW, Voelkel T, Chait BT, Gregorio CC, Rottbauer W, Tarakhovsky A, Linke WA.  Smyd2 controls cytoplasmic lysine methylation of hsp90 and myofilament organization.  Genes Dev. 2012;26:114-119.
 
93 Guan K, Cheng IF, Baazm M.  Human spermatagonial stem cells: a novel therapeutic hope for cardiac regeneration and repair?. Future Cardiol. 2012;8(1):39-51.

92 Guo W, Schafer S, Greaser ML, Radke MH, Liss M, Govindarajan T, Maatz H,Schulz H, Li S, Parrish AM, Dauksaite V, Vakeel P, Klaassen S, Gerull B,Thierfelder L, Regitz-Zagrosek V, Hacker TA, Saupe KW, Dec GW, Ellinor PT, Macrae CA, Spallek B, Fischer R, Perrot A, Ozcelik C, Saar K, Hubner N, Gotthardt M.  RBM20, a gene for hereditary cardiomyopathy, regulates titin splicing.  Nat Med. [Epub ahead of print] PubMed PMID: 2466703.

91 Ivandic BT, Mastitsky SE, Schönsiegel F, Bekeredjian R, Eils R, Frey N, Katus HA, Brors B.  Whole-genome analysis of gene expression associates the ubiquitin-proteasome system with the cardiomyopathy phenotype in disease-sensitized congenic mouse strains. Cardiovasc Res. 2012 Apr 1;94(1):87-95.

90 Keßler M, Just S, Rottbauer W.  Ion flux dependent and independent functions of ion channels in the vertebrate heart: lessons learned from zebrafish.  Stem Cells Int. 2012;2012:462161.

89 Spaich S, Will RD, Just S, Spaich S, Kuhn C, Frank D, Berger IM, Wiemann S, Korn B, Koegl M,Backs J, Katus HA, Rottbauer W, Frey N.  F-box and leucine-rich repeat protein 22 is a cardiac-enriched f-box protein that regulates sarcomeric protein turnover and is essential for maintenance of contractile function in vivo. Circ Res. 2012 Dec 7;111(12):1504-16.

88 Spomer W, Pfriem A, Alshut R, Just S, Pylatiuk C.  High-throughput screening of zebrafish embryos using automated heart detection and imaging.  Journal of laboratory automation 2012 17:435-442..
 
87 Stäehler CF, Keller A, Leidinger P, Backes C, Chandran A, Wischhusen J, Meder B, Meese E.  Whole miRNome-wide Differential Co-expression of MicroRNAs.  Genomics Proteomics Bioinformatics. 2012 Oct;10(5):285-94. doi: 10.1016/j.gpb.2012.08.003. Epub 2012 Aug 23.

86 Streckfuss-Bömeke K, Wolf F, Azizian A, Stauske M, Tiburcy M, Wagner S, Hübscher D, Dressel R, Chen S, Jende J, Wulf G, Lorenz V, Schön MP, Maier LS, Zimmermann WH, Hasenfuss G, Guan K.  Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts. (2012)  Eur Heart J,  doi:10.1093/eurheartj/ehs203 [Epub ahead of print].

85 Unsöld B, Schotola H, Jacobshagen C, Seidler T, Sossalla S, Emons J, Klede S, Knöll R, Guan K, El-Armouche A, Linke WA, Kögler H, Hasenfuss G.  Age-dependent changes in contractile function and passive elastic properties of myocardium from mice lacking muscle LIM protein (MLP). (2012)  European J Heart Fail, 14:430-437.

84 Voelkel T, Andresen C, Unger A, Just S, Rottbauer W, Linke WA.  Lysine methyltransferase Smyd2 regulates Hsp90-mediated protection of the sarcomeric titin springs and cardiac function.  Biochim Biophys Acta. 2012 Oct 6. S0167-4889(12)00281-9.

83 Vogel B, Keller A, Frese K, Kloos W, Kayvanpour E, Sedaghat-Hamedani F, Hassel S, Marquart S, Beier M, Giannitis E, Hardt S, Katus HA, Meder B.  Refining Diagnostic MicroRNA Signatures by Whole-miRNome Kinetic Analysis in Acute Myocardial Infarction.  Clin Chem. 2012 Dec 19. [Epub ahead of print].

2011

82 Buyandelger B, Ng KE, Miocic S, Piotrowska I, Gunkel S, Ku CH, Knöll R. MLP (muscle LIM protein) as a stress sensor in the heart. Pflugers Arch. 2011; 462:135-42.

81 Ehlermann P, Lehrke S, Papavassiliu T, Meder B, Borggrefe M, Katus HA, Schimpf R. Sudden cardiac death in a patient with lamin A/C mutation in the absence of dilated cardiomyopathy or conduction disease. Clin Res Cardiol. 2011 Feb 16. (epub ahead of print)

80 Haas J, Katus HA, Meder B. Next-generation sequencing entering the clinical arena. Mol Cell Probes. 2011 Sep 8. [Epub ahead of print].

79 Hippe HJ, Wolf NM, Abu-Taha HI, Lutz S, Le Lay S, Just S, Rottbauer W, Katus HA, Wieland T. Nucleoside diphosphate kinase b is required for the formation of heterotrimeric g protein containing caveolae. Naunyn Schmiedebergs Arch Pharmacol. 2011

78 Just S, Berger IM, Meder B, Backs J, Marquart S, Eva Patzel, Gerd-Jörg Rauch; Tübingen 2000 Screen Consortium; Hugo A. Katus; Wolfgang Rottbauer. Protein kinase D2 controls cardiac valve formation in zebrafish by regulating HDAC5 activity. Circulation 2011 (epub ahead of print).

77 Just S, Meder B, Berger IM, Etard C, Trano N, Patzel E, Hassel D, Marquart S, Dahme T, Vogel B, Fishman MC, Katus HA, Strahle U, Rottbauer W. The myosin-interacting protein smyd1 is essential for sarcomere organization. Journal of Cell Science 2011;124:3127-3136

76  Keller A, Harz C, Matzas M, Meder B, Katus HA, Ludwig N, Fischer U, Meese E. Identification of novel SNPs in glioblastoma using targeted resequencing. PLoS One. 2011;6(6):e18158. Epub 2011 Jun 10.

75  Keller A, Leidinger P, Bauer A, ElSharawy A, Haas J, Backes C, Wendschlag A, Giese N, Tjaden C, Ott K, Werner J, Hackert T, Ruprecht K, Huwer H, Huebers J, Jacobs G, Rosenstiel P, Dommisch H, Schaefer A, Müller-Quernheim J, Wullich B, Keck B, Graf N, Reichrath J, Vogel B, Nebel A, Jager S, Staehler P, Amarantos I, Boisguerin V, Staehler C, Beier M, Scheffler M, Büchler MW, Wischhusen J, Haeusler S, Dietl J, Hofmann S, Lenhof HP, Schreiber S, Katus HA, Rottbauer W, Meder B, Hoheisel J, Franke A, Meese E. Toward the blood-borne miRNome of human diseases. Nature Methods 2011.

74  Knöll R, Buyandelger B, Lab M. The sarcomeric Z-disc and Z-discopathies. J Biomed Biotechnol. 2011; 2011:569628.
 
73  Knöll R, Linke WA, Zou P, Miocic S, Kostin S, Buyandelger B, Ku CH, Neef S, Bug M, Schäfer K, Knöll G, Felkin LE, Wessels J, Toischer K, Hagn F, Kessler H, Didié M, Quentin T, Maier LS, Teucher N, Unsöld B, Schmidt A, Birks EJ, Gunkel S, Lang P, Granzier H, Zimmermann WH, Field LJ, Faulkner G, Dobbelstein M, Barton PJ, Sattler M, Wilmanns M, Chien KR. Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart. Circ Res. 2011; 109:758-69.

72  Meder B, Bergmann CE, Keller A, Just S, Katus HA, Hoefer IE, Buschmann IR. Quantification of Collateral Artery Growth by Automated Fluorescent Microsphere Perfusion. Int J Cardiol. 2011 May 20. [Epub ahead of print]

71  Meder B, Haas J, Keller A, Heid C, Just S, Borries A, Boisguerin V, Scharfenberger-Schmeer M, Stähler P, Beier M, Weichenhan D, Strom T, Pfeufer A, Korn B, Katus HA, Rottbauer W. Targeted Next-Generation Sequencing for the Molecular Genetic Diagnostics of Cardiomyopathies. Circulation Cardiovascular Genetics 2011 (epub ahead of print)

70  Meder B, Huttner IG, Sedaghat-Hamedani F, Just S, Dahme T, Frese KS, Vogel B, Köhler D, Kloos W, Rudloff J, Marquart S, Katus HA, Rottbauer W. PINCH proteins regulate cardiac contractility by modulating ILK-PKB signaling. Mol Cell Biol. 2011 Aug;31(16):3424-35. Epub 2011 Jun 13.

69  Meder B, Keller A, Vogel B, Haas J, Sedaghat-Hamedani F, Kayvanpour E, Just S, Borries A, Rudloff J, Leidinger P, Meese E, Katus HA, Rottbauer W. Microrna signatures in total peripheral blood as novel biomarkers for acute myocardial infarction. Basic Res Cardiol. 106:13-23 (2011)

68  Meder B, Scholz EP, Hassel D, Wolff C, Just S, Berger IM, Patzel E, Karle C, Katus HA, Rottbauer W. Reconstitution of Defective Protein Trafficking Rescues Long-QT Syndrome in Zebrafish. Biochem Biophys Res Commun. 2011 May 6;408(2):218-24. Epub 2011 Mar 31.

2010

67  Atanur SS; Birol I; Guryev V; Hirst M; Hummel O; Morrissey C; Behmoaras J; Fernandez-Suarez XM; Johnson MD; McLaren WM; Patone G; Petretto E; Plessy C; Rockland KS; Rockland C; Saar K; Zhao Y; Carninci P; Flicek P; Kurtz T; Cuppen E; Pravenec M; Huebner N; Jones SJ; Birney E; Aitman TJ. The genome sequence of the spontaneously hypertensive rat: analysis and functional significance. Genome Research 20 (6): 791-803 (2010)

66 Beckmann BM, Holinski-Feder E, Walter MC, Haserück N, Reithmann C, Hinterseer M, Wilde AA, Kääb S. Laminopathy presenting as familial atrial fibrillation. Int J Cardiol. 2010 May 14

65 Ciraolo E, Morello F, Hobbs RM, Wolf F, Marone R, Iezzi M, Lu X, Mengozzi G, Altruda F, Sorba G, Guan K, Wymann MP, Hirsch E. Essential role of the p110beta subunit of phosphoinositide 3-OH kinase in male fertility. Mol Biol Cell. 2010;21:704-711.

64 Dressel R, Nolte J, Elsner L, Novota P, Guan K, Streckfuss-Bömeke K, Hasenfuss G, Jaenisch R, Engel W. Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells. FASEB J, 2010; 24:2164-2177.

63 Ellinor PT, Lunetta KL, Glazer NL, Pfeufer A, Alonso A, Chung MK, Sinner MF, de Bakker PI, Mueller M, Lubitz SA, Fox E, Darbar D, Smith NL, Smith JD, Schnabel RB, Soliman EZ, Rice KM, Van Wagoner DR, Beckmann BM, van Noord C, Wang K, Ehret GB, Rotter JI, Hazen SL, Steinbeck G, Smith AV, Launer LJ, Harris TB, Makino S, Nelis M, Milan DJ, Perz S, Esko T, Köttgen A, Moebus S, Newton-Cheh C, Li M, Möhlenkamp S, Wang TJ, Kao WH, Vasan RS, Nöthen MM, MacRae CA, Stricker BH, Hofman A, Uitterlinden AG, Levy D, Boerwinkle E, Metspalu A, Topol EJ, Chakravarti A, Gudnason V, Psaty BM, Roden DM, Meitinger T, Wichmann HE, Witteman JC, Barnard J, Arking DE, Benjamin EJ, Heckbert SR, Kääb S. Common variants in KCNN3 are associated with lone atrial fibrillation. Nat Genet. 2010 Mar;42(3):240-4. Epub 2010 Feb 21

62 Frank D, Frauen R, Hanselmann C, Kuhn C, Will D, Gantenberg J, Füzesi L, Katus HA, Frey N. Lmcd1/Dyxin, a novel Z-disc associated LIM protein, mediates cardiac hypertrophy in vitro and in vivo. (2010) in revision.

61 Heinig M, Petretto E, Wallace C, Bottolo L, Rotival M, Lu H, Li Y, Sarwar R, Langley SR, Bauerfeind A, Hummel O, Lee YA, Paskas S, Rintisch C, Saar K, Cooper J, Buchan R, Gray EE, Cyster JG; Cardiogenics Consortium, Erdmann J, Hengstenberg C, Maouche S, Ouwehand WH, Rice CM, Samani NJ, Schunkert H, Goodall AH, Schulz H, Roider HG, Vingron M, Blankenberg S, Münzel T, Zeller T, Szymczak S, Ziegler A, Tiret L, Smyth DJ, Pravenec M, Aitman TJ, Cambien F, Clayton D, Todd JA, Hubner N, Cook SA. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature. 2010 Sep 23;467(7314):460-4.

60 Huber M, Völler H, Jakob S, Reibisa R, Do V, Bolbrinker J, Schmieder RE, Wegscheider K, Kreutz R. Role of the angiotensin II type 2-receptor gene (+1675G/A) polymorphism on left ventricular hypertrophy and geometry in treated hypertensive patients. J Hypertens. 2010 Jun;28(6):1221-9

59 Joutel A; Monet-Lepretre M; Gosele C; Baron-Menguy C; Hammes A; Schmidt S; Lemaire-Carrette B; Domenga V; Schedl A; Lacombe P; Huebner N. Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease. Journal of Clinical Investigation 120 (2): 433-445 (2010)

58 Knöll R, Kostin S, Klede S, Savvatis K, Klinge L, Stehle I, Gunkel S, Kotter S, Babicz K, Sohns M, Miocic S, Didie M, Knöll G, Zimmermann WH, Thelen P, Bickeboller H, Maier L, Schaper W, Schaper J, Kraft T, Tschope C, Linke WA, Chien KR. A Common MLP (Muscle LIM Protein) Variant Is Associated With Cardiomyopathy. Circ Res. 2010;106(4):695-704

57 Lehnart SE, Lederer WJ. An antidote for calcium leak: targeting molecular arrhythmia mechanisms. J Mol Cell Cardiol. 2010 Feb;48(2):279-82. Epub 2009 Nov 26. PMID: 19931542

56 Luedde M, Ehlermann P, Weichenhan D, Will R, Zeller R, Rupp S, Muller A, Steen H, Ivandic BT, Ulmer HE, Kern M, Katus HA, Frey N. Severe familial left ventricular non-compaction cardiomyopathy due to a novel troponin T (TNNT2) mutation. (2010) Cardiovasc Res 86(3):452-60.

55 Meder B, Keller A, Vogel B, Haas J, Sedaghat F, Kayvanpour E, Just S, Borries A, Rudloff J, Leidinger P, Meese E, Katus HA, Rottbauer W. MicroRNA Signatures in Total Peripheral Blood as Novel Biomarkers for Acute Myocardial Infarction. Basic Res Cardiol. 2010 (online first, DOI 10.1007/s00395-010-0123-2)

54 Meder, B., S. Just, B. Vogel, J. Rudloff, L. Gärtner, T. Dahme, I. Huttner, A. Zankl, H.A. Katus, W. Rottbauer. JunB-CBFß Signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure. JCS in press

53 Pfeufer A, van Noord C, Marciante KD, Arking DE, Larson MG, Smith AV, Tarasov KV, Müller M, So-toodehnia N, Sinner MF, Verwoert GC, Li M, Kao WH, Köttgen A, Coresh J, Bis JC, Psaty BM, Rice K, Rotter JI, Rivadeneira F, Hofman A, Kors JA, Stricker BH, Uitterlinden AG, van Duijn CM, Beckmann BM, Sauter W, Gieger C, Lubitz SA, Newton-Cheh C, Wang TJ, Magnani JW, Schnabel RB, Chung MK, Barnard J, Smith JD, Van Wagoner DR, Vasan RS, Aspelund T, Eiriksdottir G, Harris TB, Launer LJ, Najjar SS, Lakatta E, Schlessinger D, Uda M, Abecasis GR, Müller-Myhsok B, Ehret GB, Boerwinkle E, Chakravarti A, Soliman EZ, Lunetta KL, Perz S, Wichmann HE, Meitinger T, Levy D, Gudnason V, Elli-nor PT, Sanna S, Kääb S, Witteman JC, Alonso A, Benjamin EJ, Heckbert SR. Genome-wide association study of PR interval. Nat Genet. 2010 Feb;42(2):153-9. Epub 2010 Jan 10

52 Schoensiegel F, Ivandic B, Geis NA, Schrewe A, Katus HA, Bekeredjian R. High Throughput Echocardiography in Conscious Mice: Training and Primary Screens. Ultraschall Med. 2010 Feb 24. [Epub ahead of print]

51 Seeger TS, Frank D, Rohr C, Will R, Just S, Grund C, Lyon R, Luedde M, Koegl M, Sheikh F, Rottbauer W, Franke WW, Katus HA, Olson EN, Frey N. Myozap, a novel intercalated disc protein, activates serum response factor-dependent signaling and is required to maintain cardiac function in vivo. Circ Res. 106(5):880-90

50 Shan J, Kushnir A, Betzenhauser MJ, Reiken S, Li J, Lehnart SE, Lindegger N, Mongillo M, Mohler PJ, Marks AR. Phosphorylation of the ryanodine receptor mediates the cardiac fight or flight response in mice.  J Clin Invest  2010; 120, 4388-98

49 Wang Y; Liska F; Gosele C; Sedova L; Kren V; Krenova D; Ivics Z; Huebner N; Izsvak Z. A novel active endogenous retrovirus family contributes to genome variability in rat inbred strains. Genome Research 20 (1): 19-27 (2010) 

48 Wendt N, Schulz A, Qadri F, Bolbrinker J, Kossmehl P, Winkler K, Stoll M, Vetter R, Kreutz R. Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol.Cardiovasc Res 2009;15;81:618-626

47 Will R, Eden M, Just S, Hansen A, Eder A, Frank D, Kuhn C, Seeger TS, Oehl U, Wiemann S, Korn B, Koegl M, Rottbauer W, Eschenhagen T, Katus HA, Frey N. Myomasp/LRRC39, a heart- and muscle-specific protein, is a novel component of the sarcomeric M-band and is involved in stretch sensing. Circ Res. 2010 Sep 16. [Epub ahead of print]

2009

46 Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino RB Sr, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, Rivadeneira F, Wang TJ, Eiríksdottir G, Levy D, Psaty BM, Li M, Chamberlain AM, Hofman A, Vasan RS, Harris TB, Rotter JI, Kao WH, Agarwal SK, Stricker BH, Wang K, Launer LJ, Smith NL, Chakravarti A, Uitterlinden AG, Wolf PA, Sotoodehnia N,Köttgen A, van Duijn CM, Meitinger T, Mueller M, Perz S, Steinbeck G, Wichmann HE, Lunetta KL, Heckbert SR, Gudnason V, Alonso A, Kääb S, Ellinor PT, Witteman JC. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat Genet. 2009 Aug;41(8):879-81. Epub 2009 Jul 13

45 Dahme, T., H.A. Katus, and W. Rottbauer. (2009). Fishing for the genetic basis of cardiovascular disease. Dis Model Mech 2:18-22.

44 Dressel R, Guan K, Nolte J, Elsner L, Monecke S, Nayernia K, Hasenfuss G, Engel W. Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules. Biol Direct 2009;4:31.

43 Feltrin E, Campanaro S, Diehl AD, Ehler E, Faulkner G, Fordham J, Gardin C, Harris M, Hill D, Knöll R, Laveder P, Mittempergher L, Nori A, Reggiani C, Sorrentino V, Volpe P, Zara I, Valle G, Deegan JNC. Muscle Research and Gene Ontology: New standards for improved data integration. BMC medical genomics. 2009 2(1):6.

42 Friedrichs F, Zugck C, Rauch GJ, Ivandic B, Weichenhan D, Müller-Bardorff M, Meder B, El Mokhtari NE, Regitz-Zagrosek V, Hetzer R, Schäfer A, Schreiber S, Chen J, Neuhaus I, Ji R, Siemers NO, Frey N, Rottbauer W, Katus HA, Stoll M. HBEGF, SRA1, and IK: Three co-segregating genes as determinants of cardiomyopathy. Genome Res. 2009 Mar;19(3):395-403

41 Fuchs H, Gailus-Durner V, Adler T, Aguilar Pimentel JA, Becker L, Bolle I, Brielmeier M, Calzada-Wack J, Dalke C, Ehrhardt N, Fasnacht N, Ferwagner B, Frischmann U, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, Kallnik M, Kling E, Lengger C, Maier H, Moßbrugger I, Mörth C, Naton B, Nöth U, Pasche B, Prehn C, Przemeck G, Puk O, Racz I, Rathkolb B, Rozman J, Schäble K, Schreiner R, Schrewe A, Sina C, Steinkamp R, Thiele F, Willershäuser M, Zeh R, Adamski J, Busch DH, Beckers J, Behrendt H, Daniel H, Esposito I, Favor J, Graw J, Heldmaier G, Höfler H, Ivandic B, Katus H, Klingenspor M, Klopstock T, Lengeling A, Mempel M, Müller W, Neschen S, Ollert M, Quintanilla-Martinez L, Rosenstiel P, Schmidt J, Schreiber S, Schughart K, Schulz H, Wolf E, Wurst W, Zimmer A, Hrabé de Angelis M. The German Mouse Clinic: a platform for systemic phenotype analysis of mouse models. Curr Pharm Biotechnol. 2009 Feb;10(2):236-43. PMID: 19199957

40 Goehringer C, Rutschow D, Bauer R, Schinkel S, Weichenhan D, Bekeredjian R, Straub V, Kleinschmidt JA, Katus HA, Müller OJ. Prevention of cardiomyopathy in delta-sarcoglycan knockout mice after systemic transfer of targeted adeno-associated viral vectors. Cardiovasc Res. 2009 Jun 1;82(3):404-10. Epub 2009 Feb 13.

39 Guan K, Wolf F, Becker A, Engel W, Nayernia K, Hasenfuss G. Isolation and cultivation of stem cells from adult mouse testes. Nat Protocols. 2009;4:143-54

38 Gunkel S, Heineke J, Hilfiker-Kleiner D, Knöll R. MLP: a stress sensor goes nuclear. J Mol Cell Cardiol. 2009 47(4):423-425.

37 Gunkel S, Linke WA, Heineke J, Hilfiker-Kleiner D, Knöll R. Response to Gehmlich et al. Letter to the Editor of the Journal of Molecular and Cellular Cardiology Regarding MLP: A Stress Sensor Goes Nuclear. J Mol Cell Cardiol. 2009.

36 Hassel D, Dahme T, Erdmann J, Meder B, Huge A, Stoll M, Just S, Hess A, Ehlermann P, Weichenhan D, Grimmler M, Liptau H, Hetzer R, Regitz-Zagrosek V, Fischer C, Nürnberg P, Schunkert H, Katus HA, Rottbauer W. Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy. Nat Med. 2009 Nov;15(11):1281-8. Epub 2009 Nov 1

35 Hippe, H.J., N.M. Wolf, I. Abu-Taha, R. Mehringer, S. Just, S. Lutz, F. Niroomand, E.H. Postel, H.A. Katus, W. Rottbauer, and T. Wieland. (2009). The interaction of nucleoside diphosphate kinase B with Gbetagamma dimers controls heterotrimeric G protein function. Proc Natl Acad Sci U S A 2009 106:16269-16274.

34 Knöll R. Dilatative Kardiomyopathie - eine aktuelle Bestandsaufnahme. Med Report. 2009(9):2.

33 Knöll R. Molekulargenetische Grundlagen der dilatativen Kardiomyopathie. Der Kardiologe. 2009:3:443-452

32 Kuhn C, Frank D, Will R, Jaschinski C, Frauen R, Katus HA, Frey N. DYRK1A is a novel negative regulator of cardiomyocyte hypertrophy. (2009) J Biol Chem 284(25): 17320-17327.

31 Lehmann LH, Schaeufele T, Buss SJ, Balanova M, Hartschuh W, Ehlermann P, Katus IMAGE CARDIO MED. A patient with LEOPARD syndrome and PTPN11 mutation. Circulation. 2009 Mar 10;119(9):1328-9

30 Luedde M, Flögel U, Knorr M, Grundt C, Hippe HJ, Brors B, Frank D, HaselmannU, Antony C, Voelkers M, Schrader J, Most P, Lemmer B, Katus HA, Frey N.Decreased contractility due to energy deprivation in a transgenic rat model ofhypertrophic cardiomyopathy. J Mol Med. 2009 Apr;87(4):411-22.

29 Meder B, Katus HA, Rottbauer W. Genetik der hypertrophischen Kardiomyopathie. Journal für Kardiologie 2009

28 Meder B, Katus HA, Rottbauer W. Leichte Kette mit schweren Folgen - Der Zebrafish als Modell genetischer Herzschwäche. GenomXpress 2009; 3.09

27 Meder, B., C. Laufer, D. Hassel, S. Just, S. Marquart, B. Vogel, A. Hess, M.C. Fishman, H.A. Katus, and W. Rottbauer. (2009). A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivo. Circ Res 104:650-659

26 Morgan H, Beck T, Blake A, Gates H, Adams N, Debouzy G, Leblanc S, Lengger C, Maier H, Melvin D, Meziane H, Richardson D, Wells S, White J,Wood J, The EUMODIC Consortiumy, Hrabé de Angelis M, Brown SDM,Hancock JM and Mallon A-M. EuroPhenome: a repository for high-throughputmouse phenotyping data. Nucleic Acids Res. 2010 Jan;38 (Database issue):D577-85. doi:10.1093/nar/gkp1007 Epub 2009 Nov 23

25 Palumbo V, Segat L, Padovan L, Amoroso A, Trimarco B, Izzo R, Lembo G, Zagrosek VR, Knöll R, Brancaccio M, Tarone G, Crovella S. Melusin gene (ITGB1BP2) nucleotide variations study in hypertensive and cardiopathic patients. BMC Med Genet. 2009;10:140.

24 Pfeufer A, Sanna S, Arking DE, Müller M, Gateva V, Fuchsberger C, Ehret GB, Orrú M, Pattaro C, Köttgen A, Perz S, Usala G, Barbalic M, Li M, Pütz B, Scuteri A, Prineas RJ, Sinner MF, Gieger C, Najjar SS, Kao WH, Mühleisen TW, Dei M, Happle C, Möhlenkamp S, Crisponi L, Erbel R, Jöckel KH, NaitzaS, Steinbeck G, Marroni F, Hicks AA, Lakatta E, Müller-Myhsok B, Pramstaller PP, Wichmann HE, Schlessinger D, Boerwinkle E, Meitinger T, Uda M, Coresh J, Kääb S, Abecasis GR, Chakravarti A. Common variants at ten loci modulate the QT interval duration in the QTSCD Study Nat Genet. 2009Apr;41(4):407-14. Epub 2009 Mar 22

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22 Scholz, E.P., N. Niemer, D. Hassel, E. Zitron, H.F. Burgers, R. Bloehs, C. Seyler, D. Scherer, D. Thomas, S. Kathofer, H.A. Katus, W. Rottbauer, and C.A. Karle. (2009). Biophysical properties of zebrafish ether-a-go-go related gene potassium channels. Biochem Biophys Res Commun 381:159-164.

21 Sohns M, Rosenberger A, Bickeböller. Integration of a priori gene set information into genome-wide association studies. H. BMC Proc. 2009 Dec 15;3 Suppl 7:S95. PMID: 20018092

20 Streckfuss-Bömeke K, Vlasov A, Yin D, Hülsmann S, Nayernia K, Engel W, Hasenfuss G, Guan K. Generation of functional neurons and glia from multipotent adult mouse germline stem cells. Stem Cell Res. 2009;2:139-154

19 Tintle N, Lantieri F, Lebrec J, Sohns M, Ballard D, Bickeböller H. Inclusion of a priori information in genome-wide association analysis. Genet Epidemiol. 2009;33 Suppl 1:S74-80. PMID: 19924705

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17 Wendt N, Schulz A, Qadri F, Bolbrinker J, Kossmehl P, Winkler K, Stoll M, Vetter R, Kreutz R. Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol. Cardiovasc Res 2009;15;81:618-626

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15 Ehlermann P, Weichenhan D, Zehelein J, Steen H, Pribe R, Zeller R, Lehrke S, Zugck C, Ivandic BT, Katus HA. Adverse events in families with hypertrophic or dilated cardiomyopathy and mutations in the MYBPC3 gene. BMC Med Genet. 2008 Oct 28;9:95.

14 Geiger SK, Bär H, Ehlermann P, Wälde S, Rutschow D, Zeller R, Ivandic BT, Zentgraf H, Katus HA, Herrmann H, Weichenhan D. Incomplete nonsense-mediated decay of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardia. J Mol Med. 2008 Mar;86(3):281-9. Epub 2007 Nov 7.

13 Hassel, D., E.P. Scholz, N. Trano, O. Friedrich, S. Just, B. Meder, D.L. Weiss, E. Zitron, S. Marquart, B. Vogel, C.A. Karle, G. Seemann, M.C. Fishman, H.A. Katus, and W. Rottbauer. Deficient zebrafish ether-a-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants. Circulation. 117:866-875. 2008.

12 Hilfiker-Kleiner D, Knöll R. Disease-modifying mutations in familial hypertrophic cardiomyopathy: complexity from simplicity. Circulation. 2008 117(14):1775-1777.

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10 Lange, M., B. Kaynak, U.B. Forster, M. Tonjes, J.J. Fischer, C. Grimm, J. Schlesinger, S. Just, I. Dunkel, T. Krueger, S. Mebus, H. Lehrach, R. Lurz, J. Gobom, W. Rottbauer, S. Abdelilah-Seyfried, and S. Sperling. (2008). Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev 22:2370-2384.

9 Lehnart SE, Mongillo M, Bellinger A, Lindegger N, Chen BX, Hsueh W, Reiken S, Wronska A, Drew LJ, Ward CW, Lederer WJ, Kass RS, Morley G, Marks AR. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. J Clin Invest. 2008;118(6):2230-45

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7 Monti J; Fischer J; Paskas S; Heinig M; Schulz H; Gösele C; Heuser A; Fischer R; Schmidt C; Schirdewan A; Gross V; Hummel O; Maatz H; Patone G; Saar K; Vingron M; Weldon SM; Lindpaintner K; Hammock BD; Rohde K; Dietz R; Cook SA; Schunck WH; Luft FC; Hubner N. Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease. Nature Genetics 40 (5): 529-537 (2008).

6 Nicolaou P, Knöll R, Haghighi K, Fan GC, Dorn GW, 2nd, Hasenfub G, Kranias EG. Human mutation in the anti-apoptotic heat shock protein 20 abrogates its cardioprotective effects. The Journal of biological chemistry. 2008 283(48):33465-33471.

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4 Postel R, Vakeel P, Topczewski J, Knöll R, Bakkers J. Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex. Dev Biol. 2008 318(1):92-101.

3 Pravenec M, Churchill PC, Churchill MC, Viklicky O, Kazdova L, Aitman TJ, Petretto E, Hubner N, Wallace CA, Zimdahl H, Zidek V, Landa V, Dunbar J, Bidani A, Griffin K, Qi N, Maxova M, Kren V, Mlejnek P, Wang J, Kurtz TW. (2008) Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension. Nat Genet. 40(8):952-4

2 Thum, T., C. Gross, J. Fiedler, T. Fischer, S. Kissler, M. Bussen, P. Galuppo, S. Just, W. Rottbauer, S. Frantz, M. Castoldi, J. Soutschek, V. Koteliansky, A. Rosenwald, M.A. Basson, J.D. Licht, J.T. Pena, S.H. Rouhanifard, M.U. Muckenthaler, T. Tuschl, G.R. Martin, J. Bauersachs, and S. Engelhardt. (2008). MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 456:980-984.

1 Toischer K, Kögler H, Tenderich G, Grebe C, Seidler T, N. N, Jung K, Knöll R, Körfer R, Hasenfuss G. Elevated Afterload, Neuroendocrine Stimulation, and Human Heart Failure Increase BNP Levels and Inhibit Preload-Dependent SERCA Upregulation. Circulation Heart Failure. 2008; 1:265-271.