In a NGFN-Transfer funded study scientists from Heidelberg have developed an analytical method allowing a rapid and efficient search for genetic defects. So far, mutations in more than 30 different genes have been found to cause inherited cardiomyopathies or have an unfavorable influence on their course. For the first time it is now possible to check simultaneously and cost-efficiently all of the yet known genetic catalysts for the myocardial insufficiency. For patients and their relatives this means a more certain diagnosis and, thus, a more selective consultation, treatment and attendance.

Publikation:
Meder et al.: Targeted next-generation sequencing for the molecular genetic diagnostics of cardiomyopathies. Circ Cardiovasc Genet., 2011 Apr 1;4(2):110-22
doi: 10.1161/CIRCGENETICS.110.958322